Department of Pediatric Hematology and Oncology

Publications

  1. 2024
  2. Reintegration into school, kindergarten and work in families of childhood cancer survivors after a family-oriented rehabilitation program

    Inhestern, L., Nasse, M. L., Krauth, K. A., Kandels, D., Rutkowski, S., Escherich, G. & Bergelt, C., 07.03.2024, In: FRONT PEDIATR. 12, p. 1288567

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. A Multimodal Lifestyle Psychosocial Survivorship Program in Young Cancer Survivors: The CARE for CAYA Program-A Randomized Clinical Trial Embedded in a Longitudinal Cohort Study

    von Grundherr, J., Elmers, S., Koch, B., Hail, L-A., Mann, J., Escherich, G., Bergelt, C., Samland, L., Jensen, W., Vettorazzi, E., Stark, M., Valentini, L., Baumann, F. T., Singer, S., Reer, R., Beller, R., Calaminus, G., Faber, J., Classen, C. F., Gebauer, J., Hilgendorf, I., Koehler, M., Puzik, A., Salzmann, N., Sander, A., Schiffmann, L., Sokalska-Duhme, M., Schuster, S., Kock-Schoppenhauer, A-K., Bokemeyer, C., Sinn, M., Stein, A., Dwinger, S. & Salchow, J., 04.03.2024, In: JAMA NETW OPEN. 7, 3, p. e242375

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Molecular refinement of pilocytic astrocytoma in adult patients

    Bode, H., Kresbach, C., Holdhof, D., Dorostkar, M. M., Harter, P. N., Hench, J., Frank, S., Suwala, A. K., Schweizer, L., Eckhardt, A., Neyazi, S., Bockmayr, M., Wefers, A. K. & Schüller, U., 02.2024, In: NEUROPATH APPL NEURO. 50, 1, p. e12949

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation

    Neyazi, S., Yamazawa, E., Hack, K., Tanaka, S., Nagae, G., Kresbach, C., Umeda, T., Eckhardt, A., Tatsuno, K., Pohl, L., Hana, T., Bockmayr, M., Kim, P., Dorostkar, M. M., Takami, T., Obrecht, D., Takai, K., Suwala, A. K., Komori, T., Godbole, S., Wefers, A. K., Otani, R., Neumann, J. E., Higuchi, F., Schweizer, L., Nakanishi, Y., Monoranu, C-M., Takami, H., Engertsberger, L., Yamada, K., Ruf, V., Nomura, M., Mohme, T., Mukasa, A., Herms, J., Takayanagi, S., Mynarek, M., Matsuura, R., Lamszus, K., Ishii, K., Kluwe, L., Imai, H., von Deimling, A., Koike, T., Benesch, M., Kushihara, Y., Snuderl, M., Nambu, S., Frank, S., Omura, T., Hagel, C., Kugasawa, K., Mautner, V. F., Ichimura, K., Rutkowski, S., Aburatani, H., Saito, N. & Schüller, U., 24.01.2024, In: ACTA NEUROPATHOL. 147, 1, p. 22

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma

    Drexler, R., Khatri, R., Schüller, U., Eckhardt, A., Ryba, A., Sauvigny, T., Dührsen, L., Mohme, M., Ricklefs, T., Bode, H., Hausmann, F., Huber, T. B., Bonn, S., Voß, H., Neumann, J. E., Silverbush, D., Hovestadt, V., Suvà, M. L., Lamszus, K., Gempt, J., Westphal, M., Heiland, D. H., Hänzelmann, S. & Ricklefs, F. L., 20.01.2024, In: ACTA NEUROPATHOL. 147, 1, p. 21

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct clinicopathological and molecular features

    Dottermusch, M., Ryba, A., Ricklefs, F. L., Flitsch, J., Schmid, S., Glatzel, M., Saeger, W., Neumann, J. E. & Schüller, U., 16.01.2024, In: ACTA NEUROPATHOL. 147, 1, p. 16

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Unclassifiable CNS tumors in DNA methylation-based classification: clinical challenges and prognostic impact

    Drexler, R., Brembach, F., Sauvigny, J., Ricklefs, F. L., Eckhardt, A., Bode, H., Gempt, J., Lamszus, K., Westphal, M., Schüller, U. & Mohme, M., 16.01.2024, In: ACTA NEUROPATHOL COM. 12, 1, p. 9

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. And what about today? Burden and support needs of adolescent childhood cancer survivors in long-term follow-up care-A qualitative content analysis

    Winzig, J., Inhestern, L., Sigmund, D., Paul, V., Hail, L-A., Rutkowski, S., Escherich, G. & Bergelt, C., 01.2024, In: CHILD CARE HLTH DEV. 50, 1, p. e13207

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Child-centredness in paediatric magnetic resonance imaging: Information needs and experiences of children requiring magnetic resonance imaging and their parents

    Inhestern, L., Herrmann, J., Schürmann, J., Meister, R. L., Nawka, M. T., Mynarek, M., Linhart, D. & Bergelt, C., 01.2024, In: CHILD CARE HLTH DEV. 50, 1, p. e13157

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. 2023
  12. Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome

    Kolodziejczak, A. S., Guerrini-Rousseau, L., Planchon, J. M., Ecker, J., Selt, F., Mynarek, M., Obrecht, D., Sill, M., Autry, R. J., Zhao, E., Hirsch, S., Amouyal, E., Dufour, C., Ayrault, O., Torrejon, J., Waszak, S. M., Ramaswamy, V., Pentikainen, V., Demir, H. A., Clifford, S. C., Schwalbe, E. C., Massimi, L., Snuderl, M., Galbraith, K., Karajannis, M. A., Hill, K., Li, B. K., Walsh, M., White, C. L., Redmond, S., Loizos, L., Jakob, M., Kordes, U. R., Schmid, I., Hauer, J., Blattmann, C., Filippidou, M., Piccolo, G., Scheurlen, W., Farrag, A., Grund, K., Sutter, C., Pietsch, T., Frank, S., Schewe, D. M., Malkin, D., Ben-Arush, M., Sehested, A., Wong, T-T., Wu, K-S., Liu, Y-L., Carceller, F., Mueller, S., Stoller, S., Taylor, M. D., Tabori, U., Bouffet, E., Kool, M., Sahm, F., von Deimling, A., Korshunov, A., von Hoff, K., Kratz, C. P., Sturm, D., Jones, D. T. W., Rutkowski, S., van Tilburg, C. M., Witt, O., Bougeard, G., Pajtler, K. W., Pfister, S. M., Bourdeaut, F. & Milde, T., 08.12.2023, In: NEURO-ONCOLOGY. 25, 12, p. 2273-2286 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Development of a centralised triage centre for children with cancer and blood disorders in response to the humanitarian crisis in Ukraine

    Salek, M., Mueller, A., Alanbousi, I., Cepowska, Z., Dutkiewicz, M., Earl, J., Evseev, D., Kizyma, R., Kliuchkivska, K., Kolodrubiec, J., Matczak, K., Nogovitsyna, Y., Oszer, A., Pogorelyy, M., Raciborska, A., Rasul, S., Sokolowski, I., Sopilnyak, A., Vinitsky, A., Wlodarski, M. W., Wobst, N., Yakimkova, T., Rodriguez-Galindo, C., Wise, P. H., Mlynarski, W., Agulnik, A. & SAFER Ukraine Collaborative, 12.2023, In: LANCET ONCOL. 24, 12, p. 1315-1318 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  14. Solid pseudopapillary neoplasms of the pancreas in childhood and adolescence-an analysis of the German Registry for Rare Pediatric Tumors (STEP)

    Jentzsch, C., Fuchs, J., Agaimy, A., Vokuhl, C., Escherich, G., Blattmann, C., Warmann, S. W., Schmidt, A., Schäfer, J., Brecht, I. B., Schneider, D. T. & Abele, M., 12.2023, In: EUR J PEDIATR. 182, 12, p. 5341-5352 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures

    Schoof, M., Godbole, S., Albert, T. K., Dottermusch, M., Walter, C., Ballast, A., Qin, N., Olivera, M. B., Göbel, C., Neyazi, S., Holdhof, D., Kresbach, C., Peter, L-S., Epplen, G. D., Thaden, V., Spohn, M., Blattner-Johnson, M., Modemann, F., Mynarek, M., Rutkowski, S., Sill, M., Varghese, J., Afflerbach, A-K., Eckhardt, A., Münter, D., Verma, A., Struve, N., Jones, D. T. W., Remke, M., Neumann, J. E., Kerl, K. & Schüller, U., 24.11.2023, In: NAT COMMUN. 14, 1, p. 7717

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Phase II Trial of Dabrafenib Plus Trametinib in Relapsed/Refractory BRAF V600–Mutant Pediatric High-Grade Glioma

    Hargrave, D. R., Terashima, K., Hara, J., Kordes, U., Upadhyaya, S., Sahm, F., Bouffet, E., Packer, R. J., Witt, O., Sandalic, L., Kieloch, A., Russo, M. & Cohen, K., 20.11.2023, In: J CLIN ONCOL. 41, 33, p. 5174-5183 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Outcome for Children and Young Adults With T-Cell ALL and Induction Failure in Contemporary Trials

    Raetz, E. A., Rebora, P., Conter, V., Schrappe, M., Devidas, M., Escherich, G., Imai, C., De Moerloose, B., Schmiegelow, K., Burns, M. A., Elitzur, S., Pieters, R., Attarbaschi, A., Yeoh, A., Pui, C-H., Stary, J., Cario, G., Bodmer, N., Moorman, A. V., Buldini, B., Vora, A. & Valsecchi, M. G., 10.11.2023, In: J CLIN ONCOL. 41, 32, p. 5025-5034 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice

    Göbel, C., Godbole, S., Schoof, M., Holdhof, D., Kresbach, C., Loose, C., Neumann, J. & Schüller, U., 02.11.2023, In: ACTA NEUROPATHOL COM. 11, 1, p. 174

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Th1 cytokines in pediatric acute lymphoblastic leukemia

    Schober, S., Rottenberger, J. M., Hilz, J., Schmid, E., Ebinger, M., Feuchtinger, T., Handgretinger, R., Lang, P. & Queudeville, M., 11.2023, In: CANCER IMMUNOL IMMUN. 72, 11, p. 3621-3634 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Health-Related Quality of Life and Mental Health of Children with Embryonal Abdominal Tumors

    Behrendt, P., Boettcher, M., Zierke, K. T., Najem, S., Zapf, H., Reinshagen, K., Wößmann, W. & Boettcher, J., 23.10.2023, In: CHILDREN-BASEL. 10, 10, 1720.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Multimodal cartography of human lymphopoiesis reveals B and T/NK/ILC lineages are subjected to differential regulation

    Alhaj Hussen, K., Chabaane, E., Nelson, E., Lekiashvili, S., Diop, S., Keita, S., Evrard, B., Lardenois, A., Delord, M., Verhoeyen, E., Cornils, K., Kasraian, Z., Macintyre, E. A., Cumano, A., Garrick, D., Goodhardt, M., Andrieu, G. P., Asnafi, V., Chalmel, F. & Canque, B., 20.10.2023, In: ISCIENCE. 26, 10, 107890.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Rhabdoid tumors in patients conceived following ART: is there an association?

    Nemes, K., Benesch, M., Kolarova, J., Johann, P., Hasselblatt, M., Thomas, C., Bens, S., Glaser, S., Ammerpohl, O., Liaugaudiene, O., Sadeghipour, A., von der Weid, N., Schmid, I., Gidding, C., Erdreich-Epstein, A., Khurana, C., Ebetsberger-Dachs, G., Lemmer, A., Khatib, Z., Hernández Marqués, C., Pears, J., Quehenberger, F., Kordes, U., Vokuhl, C., Gerss, J., Schwarz, H., Bison, B., Biegel, J. A., Siebert, R. & Frühwald, M. C., 03.10.2023, In: HUM REPROD. 38, 10, p. 2028-2038 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. ABL-class Genomic Breakpoint Q-PCR: A Patient-specific Approach for MRD Monitoring in Acute Lymphoblastic Leukemia

    van Outersterp, I., van der Velden, V. H. J., Hoogeveen, P. G., Vaitkevičienė, G. E., Sonneveld, E., van Haaften, G., Kuiper, R. P., Zur Stadt, U., Escherich, G., Boer, J. M. & den Boer, M. L., 10.2023, In: HEMASPHERE. 7, 10, p. e967

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  24. Activated phosphoinositide 3-kinase δ syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity

    Maccari, M. E., Wolkewitz, M., Schwab, C., Lorenzini, T., Leiding, J. W., Aladjdi, N., Abolhassani, H., Abou-Chahla, W., Aiuti, A., Azarnoush, S., Baris, S., Barlogis, V., Barzaghi, F., Baumann, U., Bloomfield, M., Bohynikova, N., Bodet, D., Boutboul, D., Bucciol, G., Buckland, M. S., Burns, S. O., Cancrini, C., Cathébras, P., Cavazzana, M., Cheminant, M., Chinello, M., Ciznar, P., Coulter, T. I., D'Aveni, M., Ekwall, O., Eric, Z., Eren, E., Fasth, A., Frange, P., Fournier, B., Garcia-Prat, M., Gardembas, M., Geier, C., Ghosh, S., Goda, V., Hammarström, L., Hauck, F., Heeg, M., Heropolitanska-Pliszka, E., Hilfanova, A., Jolles, S., Karakoc-Aydiner, E., Kindle, G. R., Kiykim, A., Klemann, C., Koletsi, P., Koltan, S., Kondratenko, I., Körholz, J., Krüger, R., Jeziorski, E., Levy, R., Le Guenno, G., Lefevre, G., Lougaris, V., Marzollo, A., Mahlaoui, N., Malphettes, M., Meinhardt, A., Merlin, E., Meyts, I., Milota, T., Moreira, F., Moshous, D., Mukhina, A., Neth, O., Neubert, J., Neven, B., Nieters, A., Nove-Josserand, R., Oksenhendler, E., Ozen, A., Olbrich, P., Perlat, A., Pac, M., Schmid, J. P., Pacillo, L., Parra-Martinez, A., Paschenko, O., Pellier, I., Sefer, A. P., Plebani, A., Plantaz, D., Prader, S., Raffray, L., Ritterbusch, H., Riviere, J. G., Rivalta, B., Rusch, S., Sakovich, I., Savic, S., Scheible, R., Schleinitz, N., Schuetz, C., Schulz, A., Sediva, A., Semeraro, M., Sharapova, S. O., Shcherbina, A., Slatter, M. A., Sogkas, G., Soler-Palacin, P., Speckmann, C., Stephan, J-L., Suarez, F., Tommasini, A., Trück, J., Uhlmann, A., van Aerde, K. J., van Montfrans, J., von Bernuth, H., Warnatz, K., Williams, T., Worth, A. J. J., Ip, W., Picard, C., Catherinot, E., Nademi, Z., Grimbacher, B., Forbes Satter, L. R., Kracker, S., Chandra, A., Condliffe, A. M., Ehl, S. & European Society for Immunodeficiencies Registry Working Party, 10.2023, In: J ALLERGY CLIN IMMUN. 152, 4, p. 984-996.e10

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Epigenetic profiling reveals a strong association between lack of 5-ALA fluorescence and EGFR amplification in IDH-wildtype glioblastoma

    Drexler, R., Sauvigny, T., Schüller, U., Eckhardt, A., Maire, C. L., Khatri, R., Hausmann, F., Hänzelmann, S., Huber, T. B., Bonn, S., Bode, H., Lamszus, K., Westphal, M., Dührsen, L. & Ricklefs, F. L., 10.2023, In: NEURO-ONCOL PRACT. 10, 5, p. 462-471 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Parent-reported health-related quality of life in pediatric childhood cancer survivors and factors associated with poor health-related quality of life in aftercare

    Winzig, J., Inhestern, L., Paul, V., Nasse, M. L., Krauth, K. A., Kandels, D., Rutkowski, S., Escherich, G. & Bergelt, C., 10.2023, In: QUAL LIFE RES. 32, 10, p. 2965-2974 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. hGFAP-mediated GLI2 overexpression leads to early death and severe cerebellar malformations with rare tumor formation

    Niesen, J., Hermans-Borgmeyer, I., Krüger, C., Schoof, M., Modemann, F. & Schüller, U., 15.09.2023, In: ISCIENCE. 26, 9, p. 107501

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Atypical Neurofibromas reveal distinct epigenetic features with proximity to benign peripheral nerve sheath tumor entities

    Kresbach, C., Dottermusch, M., Eckhardt, A., Ristow, I., Paplomatas, P., Altendorf, L., Wefers, A. K., Bockmayr, M., Belakhoua, S., Tran, I., Pohl, L., Neyazi, S., Bode, H., Farschtschi, S., Well, L., Friedrich, R. E., Reuss, D., Snuderl, M., Hagel, C., Mautner, V-F. & Schüller, U., 05.09.2023, In: NEURO-ONCOLOGY. 25, 9, p. 1644-1655 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics

    Johann, P. D., Altendorf, L., Efremova, E-M., Holsten, T., Steinbügl, M., Nemes, K., Eckhardt, A., Kresbach, C., Bockmayr, M., Koch, A., Haberler, C., Antonelli, M., DeSisto, J., Schuhmann, M. U., Hauser, P., Siebert, R., Bens, S., Kool, M., Green, A. L., Hasselblatt, M., Frühwald, M. C. & Schüller, U., 09.2023, In: ACTA NEUROPATHOL. 146, 3, p. 527-541 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability

    Drexler, R., Khatri, R., Sauvigny, T., Mohme, M., Maire, C. L., Ryba, A., Zghaibeh, Y., Dührsen, L., Salviano-Silva, A., Lamszus, K., Westphal, M., Gempt, J., Wefers, A. K., Neumann, J., Bode, H., Hausmann, F., Huber, T. B., Bonn, S., Jütten, K., Delev, D., Weber, K. J., Harter, P. N., Onken, J., Vajkoczy, P., Capper, D., Wiestler, B., Weller, M., Snijder, B., Buck, A., Weiss, T., Keough, M. B., Ni, L., Monje, M., Silverbush, D., Hovestadt, V., Suvà, M. L., Krishna, S., Hervey-Jumper, S. L., Schüller, U., Heiland, D. H., Hänzelmann, S. & Ricklefs, F. L., 07.08.2023, In: bioRxiv.

    Research output: SCORING: Contribution to journalPreprintResearch

  31. Risk prediction in early childhood sonic hedgehog medulloblastoma treated with radiation-avoiding chemotherapy

    Tonn, S., Korshunov, A., Obrecht, D., Sill, M., Spohn, M., von Hoff, K., Milde, T., Pietsch, T., Goschzik, T., Bison, B., Juhnke, B-O., Struve, N., Sturm, D., Sahm, F., Bockmayr, M., Friedrich, C., von Bueren, A. O., Gerber, N. U., Benesch, M., Jones, D. T. W., Kool, M., Wefers, A. K., Schüller, U., Pfister, S. M., Rutkowski, S. & Mynarek, M., 03.08.2023, In: NEURO-ONCOLOGY. 25, 8, p. 1518-1529 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Rapid Determination of Nutmeg Shell Content in Ground Nutmeg Using FT-NIR Spectroscopy and Machine Learning

    Drees, A., Bockmayr, B., Bockmayr, M. & Fischer, M., 02.08.2023, In: FOODS. 12, 15, 2939.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Emotional and behavioral problems of pediatric cancer survivors and their siblings: Concordance of child self-report and parent proxy-report

    Paul, V., Inhestern, L., Winzig, J., Nasse, M. L., Krauth, K. A., Rutkowski, S., Escherich, G. & Bergelt, C., 08.2023, In: PSYCHO-ONCOLOGY. 32, 8, p. 1248-1256 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Glyco-binding domain chimeric antigen receptors as a new option for cancer immunotherapy

    Franke, A-K., Wessolowski, C., Thaden, V., Müller, I. & Cornils, K., 08.2023, In: GENE THER. 30, 7-8, p. 603-611 9 p.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  35. Mitochondrial DNA mutations in Medulloblastoma

    Funke, V. L. E., Sandmann, S., Melcher, V., Seggewiss, J., Horvath, J., Jäger, N., Kool, M., Jones, D. T. W., Pfister, S. M., Milde, T., Rutkowski, S., Mynarek, M., Varghese, J., Sträter, R., Rust, S., Seelhöfer, A., Reunert, J., Fiedler, B., Schüller, U., Marquardt, T. & Kerl, K., 27.07.2023, In: ACTA NEUROPATHOL COM. 11, 1, p. 124

    Research output: SCORING: Contribution to journalCase reportResearchpeer-review

  36. Reduced Humoral and Cellular Immune Response to Primary COVID-19 mRNA Vaccination in Kidney Transplanted Children Aged 5–11 Years

    Lalia, J. K., Schild, R-S., Lütgehetmann, M., Dunay, G. A., Kallinich, T., Kobbe, R., Massoud, M., Oh, J., Pietzsch, L., Schulze-Sturm, U., Schuetz, C., Sibbertsen, F., Speth, F., Thieme, S., Witkowski, M., Berner, R., Muntau, A. C., Gersting, S. W., Toepfner, N., Pagel, J. & Paul, K., 14.07.2023, In: VIRUSES-BASEL. 15, 7, p. 1553

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Adult intracranial ependymoma-relevance of DNA methylation profiling for diagnosis, prognosis, and treatment

    Träger, M., Schweizer, L., Pérez, E., Schmid, S., Hain, E. G., Dittmayer, C., Onken, J., Fukuoka, K., Ichimura, K., Schüller, U., Dührsen, L., Müther, M., Paulus, W., Thomas, C., Gutt-Will, M., Schucht, P., Maragkou, T., Schittenhelm, J., Eckert, F., Niyazi, M., Fleischmann, D. F., Dorostkar, M. M., Feyer, P., May, S-A., Moskopp, D., Badakhshi, H., Radke, C., Walter, J., Ehret, F., Capper, D. & Kaul, D., 06.07.2023, In: NEURO-ONCOLOGY. 25, 7, p. 1286-1298 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model

    Ehm, P., Rietow, R., Wegner, W., Bußmann, L., Kriegs, M., Dierck, K., Horn, S., Streichert, T., Horstmann, M. & Jücker, M., 06.07.2023, In: CELLS-BASEL. 12, 13, p. 1798

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. The tumor suppressor CREBBP and the oncogene MYCN cooperate to induce malignant brain tumors in mice

    Schoof, M., Epplen, G. D., Walter, C., Ballast, A., Holdhof, D., Göbel, C., Neyazi, S., Varghese, J., Albert, T. K., Kerl, K. & Schüller, U., 05.07.2023, In: ONCOGENESIS. 12, 1, p. 36

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Prospective Newborn Screening for SCID in Germany: A First Analysis by the Pediatric Immunology Working Group (API)

    Speckmann, C., Nennstiel, U., Hönig, M., Albert, M. H., Ghosh, S., Schuetz, C., Brockow, I., Hörster, F., Niehues, T., Ehl, S., Wahn, V., Borte, S., Lehmberg, K., Baumann, U., Beier, R., Krüger, R., Bakhtiar, S., Kuehl, J-S., Klemann, C., Kontny, U., Holzer, U., Meinhardt, A., Morbach, H., Naumann-Bartsch, N., Rothoeft, T., Kreins, A. Y., Davies, E. G., Schneider, D. T., Bernuth, H. V., Klingebiel, T., Hoffmann, G. F., Schulz, A. & Hauck, F., 07.2023, In: J CLIN IMMUNOL. 43, 5, p. 965-978 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Group-specific cellular metabolism in Medulloblastoma

    Funke, V. L. E., Walter, C., Melcher, V., Wei, L., Sandmann, S., Hotfilder, M., Varghese, J., Jäger, N., Kool, M., Jones, D. T. W., Pfister, S. M., Milde, T., Mynarek, M., Rutkowski, S., Seggewiss, J., Jeising, D., de Faria, F. W., Marquardt, T., Albert, T. K., Schüller, U. & Kerl, K., 05.06.2023, In: J TRANSL MED. 21, 1, p. 363

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Generalized Infantile Myofibromatosis with Extensive Small Bowel Involvement in a Neonate

    Schubert, J. P., Wößmann, W., Königs, I., Clauditz, T., Kordes, U. & Reinshagen, K., 06.2023, In: Z GEBURTSH NEONATOL. 227, 3, p. 231-235 5 p.

    Research output: SCORING: Contribution to journalCase reportResearchpeer-review

  43. Long-term sequelae after immunotherapeutic approaches in haematological malignancies-what do we know?

    Escherich, G. & Hough, R., 06.2023, In: LANCET HAEMATOL. 10, 6, p. e395-e396

    Research output: SCORING: Contribution to journalComment/debateResearch

  44. Preclinical patient-derived modeling of castration-resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease

    Elsesy, M. E., Oh-Hohenhorst, S. J., Oing, C., Eckhardt, A., Burdak-Rothkamm, S., Alawi, M., Müller, C., Schüller, U., Maurer, T., von Amsberg, G., Petersen, C., Rothkamm, K. & Mansour, W. Y., 06.2023, In: MOL ONCOL. 17, 6, p. 1129-1147 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes

    Korshunov, A., Okonechnikov, K., Schrimpf, D., Tonn, S., Mynarek, M., Koster, J., Sievers, P., Milde, T., Sahm, F., Jones, D. T. W., von Deimling, A., Pfister, S. M. & Kool, M., 06.2023, In: ACTA NEUROPATHOL. 145, 6, p. 829-842 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Kinder und Jugendliche mit intrakraniellem Ependymom – Empfehlungen der HIT-MED-Studiengruppe der GPOH zur Erstlinientherapie

    Obrecht, D., Mynarek, M., Stickan-Verfürth, M., Bison, B., Schüller, U., Pajtler, K., Hagel, C., Thomale, U-W., Fleischhack, G., Timmermann, B. & Rutkowski, S., 12.05.2023, In: KLIN PADIATR. 235, 3, p. 167-177 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Targeted anticonvulsive treatment of IDH-wildtype glioblastoma based on DNA methylation subclasses

    Drexler, R., Göttsche, J., Sauvigny, T., Schüller, U., Khatri, R., Hausmann, F., Hänzelmann, S., Huber, T. B., Bonn, S., Heiland, D. H., Delev, D., Venkataramani, V., Winkler, F., Weller, J., Zeyen, T., Herrlinger, U., Gempt, J., Ricklefs, F. L. & Dührsen, L., 04.05.2023, In: NEURO-ONCOLOGY. 25, 5, p. 1006-1008 3 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  48. Combination therapy with crizotinib and vinblastine for relapsed or refractory pediatric ALK-positive anaplastic large cell lymphoma

    Knörr, F., Schellekens, K. P. J., Schoot, R. A., Landman-Parker, J., Teltschik, H-M., Förster, J., Riquelme, A., Huitema, A. D. R., Van Eijkelenburg, N. K. A., Beishuizen, A., Zwaan, C. M., Woessmann, W. & Van der Lugt, J., 01.05.2023, In: HAEMATOLOGICA. 108, 5, p. 1442-1446 5 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  49. Evaluating the safety of perioperative dexamethasone treatment: A retrospective analysis of a single center pediatric low-grade glioma cohort

    Gorodezki, D., Zipfel, J., Queudeville, M., Holzer, U., Bevot, A., Schittenhelm, J., Nägele, T., Schuhmann, M. U. & Ebinger, M., 01.05.2023, In: INT J CANCER. 152, 9, p. 1875-1883 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Antimicrobial use in pediatric oncology and hematology in Germany and Austria, 2020/2021: a cross-sectional, multi-center point-prevalence study with a multi-step qualitative adjudication process

    Papan, C., Reifenrath, K., Last, K., Attarbaschi, A., Graf, N., Groll, A. H., Hübner, J., Laws, H-J., Lehrnbecher, T., Liese, J. G., Martin, L., Tenenbaum, T., Vieth, S., von Both, U., Wagenpfeil, G., Weichert, S., Hufnagel, M., Simon, A. & AB-PPS PedOnc Study Group, 05.2023, In: LANCET REG HEALTH-EU. 28, p. 100599

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Correction: Impact of COVID-19 Related Restrictions on Infections in Children with Cancer or after Hematopoietic SCT

    Hauch, R., Hinrichs, M., Ruhwald, R., Schrum, J., Rutkowski, S., Woessmann, W. & Winkler, B., 05.2023, In: KLIN PADIATR. 235, 3, p. e1-e2

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  52. Generation of new transgenic SMARCA4-deficient mouse models results in neuromuscular weakness and paralysis of limbs

    Neyazi, S., Altendorf, L., Schwetje, D., Göbel, C., Schoof, M., Holdhof, D. & Schüller, U., 05.2023, In: BRAIN PATHOL. 33, 3, p. e13146

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  53. Impact of COVID-19 Related Restrictions on Infections in Children with Cancer or after Hematopoietic SCT: A Monocentric, Retrospective Study

    Hauch, R., Hinrichs, M., Ruhwald, R., Schrum, J., Rutkowski, S., Woessmann, W. & Winkler, B., 05.2023, In: KLIN PADIATR. 235, 3, p. 159-166 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. Isolated extradural sacrococcygeal ependymoma mimicking teratoma in a 5-year-old boy

    Claviez, A., Moritz, J. D., Yuan, M., Vieth, S., Bergholz, R., Ahmeti, H. & Schüller, U., 05.2023, In: KLIN PADIATR. 235, 3, p. 185-187 3 p.

    Research output: SCORING: Contribution to journalCase reportResearchpeer-review

  55. Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification

    Goddard, J., Castle, J., Southworth, E., Fletcher, A., Crosier, S., Martin-Guerrero, I., García-Ariza, M., Navajas, A., Masliah-Planchon, J., Bourdeaut, F., Dufour, C., Ayrault, O., Goschzik, T., Pietsch, T., Sill, M., Pfister, S. M., Rutkowski, S., Richardson, S., Hill, R. M., Williamson, D., Bailey, S., Schwalbe, E. C., Clifford, S. C. & Hicks, D., 05.2023, In: ACTA NEUROPATHOL. 145, 5, p. 651-666 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  56. Multiple sclerosis, disease-modifying drugs and risk for adverse perinatal and pregnancy outcomes: Results from a population-based cohort study

    Fink, K., Gorczyca, A., Alping, P., Englund, S., Farmand, S., Langer-Gould, A. M., Piehl, F., McKay, K., Frisell, T. & Razaz, N., 05.2023, In: MULT SCLER J. 29, 6, p. 731-740 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  57. The Prognostic Effect of IKZF1 Deletions in ETV6::RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

    Østergaard, A., Enshaei, A., Pieters, R., Vora, A., Horstmann, M. A., Escherich, G., Johansson, B., Heyman, M., Schmiegelow, K., Hoogerbrugge, P. M., den Boer, M. L., Kuiper, R. P., Moorman, A. V., Boer, J. M. & van Leeuwen, F. N., 05.2023, In: HEMASPHERE. 7, 5, p. e875

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  58. Blinatumomab Added to Chemotherapy in Infant Lymphoblastic Leukemia

    van der Sluis, I. M., de Lorenzo, P., Kotecha, R. S., Attarbaschi, A., Escherich, G., Nysom, K., Stary, J., Ferster, A., Brethon, B., Locatelli, F., Schrappe, M., Scholte-van Houtem, P. E., Valsecchi, M. G. & Pieters, R., 27.04.2023, In: NEW ENGL J MED. 388, 17, p. 1572-1581 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  59. MAP kinase activating death domain deficiency is a novel cause of impaired lymphocyte cytotoxicity

    Schütze, K., Groß, M., Cornils, K., Wustrau, K., Schneppenheim, S., Lenhartz, H., Korenke, G-C., Janka, G., Ledig, S., Müller, I., Ehl, S. & Lehmberg, K., 25.04.2023, In: BLOOD ADV. 7, 8, p. 1531-1535 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  60. Elevated RIPK3 correlates with disease burden in myelofibrosis

    Dill, V., Wagner, C. V., Keller, E. C., Fernandez-Hernandez, F. J., Shoumariyeh, K., Odinius, T. O., Buschhorn, L., Hauch, R. T., Suren, C., Hecker, J. S., Herhaus, P., Sandherr, M., Schmidt, B., Slotta-Huspenina, J., Bassermann, F., Höckendorf, U., Jilg, S., Branca, C., Vosberg, S. & Jost, P. J., 11.04.2023, In: BLOOD ADV. 7, 7, p. 1219-1224 6 p.

    Research output: SCORING: Contribution to journalLetterResearch

  61. Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study

    Erker, C., Mynarek, M., Bailey, S., Mazewski, C. M., Baroni, L., Massimino, M., Hukin, J., Aguilera, D., Cappellano, A. M., Ramaswamy, V., Lassaletta, A., Perreault, S., Kline, C. N., Rajagopal, R., Michaiel, G., Zapotocky, M., Santa-Maria Lopez, V., La Madrid, A. M., Cacciotti, C., Sandler, E. S., Hoffman, L. M., Klawinski, D., Khan, S., Salloum, R., Hoppmann, A. L., Larouche, V., Dorris, K., Toledano, H., Gilheeney, S. W., Abdelbaki, M. S., Wilson, B., Tsang, D. S., Knipstein, J., Oren, M. Y., Shah, S., Murray, J. C., Ginn, K. F., Wang, Z. J., Fleischhack, G., Obrecht, D., Tonn, S., Harrod, V. L., Matheson, K., Crooks, B., Strother, D. R., Cohen, K. J., Hansford, J. R., Mueller, S., Margol, A., Gajjar, A., Dhall, G., Finlay, J. L., Northcott, P. A., Rutkowski, S., Clifford, S. C., Robinson, G., Bouffet, E. & Lafay-Cousin, L., 01.04.2023, In: J CLIN ONCOL. 41, 10, p. 1921-1932 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  62. Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology

    Sturm, D., Capper, D., Andreiuolo, F., Gessi, M., Kölsche, C., Reinhardt, A., Sievers, P., Wefers, A. K., Ebrahimi, A., Suwala, A. K., Gielen, G. H., Sill, M., Schrimpf, D., Stichel, D., Hovestadt, V., Daenekas, B., Rode, A., Hamelmann, S., Previti, C., Jäger, N., Buchhalter, I., Blattner-Johnson, M., Jones, B. C., Warmuth-Metz, M., Bison, B., Grund, K., Sutter, C., Hirsch, S., Dikow, N., Hasselblatt, M., Schüller, U., Gerber, N. U., White, C. L., Buntine, M. K., Kinross, K., Algar, E. M., Hansford, J. R., Gottardo, N. G., Hernáiz Driever, P., Gnekow, A., Witt, O., Müller, H. L., Calaminus, G., Fleischhack, G., Kordes, U., Mynarek, M., Rutkowski, S., Frühwald, M. C., Kramm, C. M., von Deimling, A., Pietsch, T., Sahm, F., Pfister, S. M. & Jones, D. T. W., 04.2023, In: NAT MED. 29, 4, p. 917-926 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  63. Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo

    Genduso, S., Freytag, V., Schetler, D., Kirchner, L., Schiecke, A., Maar, H., Wicklein, D., Gebauer, F., Bröker, K., Stürken, C., Milde-Langosch, K., Oliveira-Ferrer, L., Ricklefs, F. L., Ewald, F., Wolters-Eisfeld, G., Riecken, K., Unrau, L., Krause, L., Bohnenberger, H., Offermann, A., Perner, S., Sebens, S., Lamszus, K., Diehl, L., Linder, S., Jücker, M., Schumacher, U. & Lange, T., 17.03.2023, In: J HEMATOL ONCOL. 16, 1, 23.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  64. Epigenetic Modification of Mesenchymal Stromal Cells Derived from Bone Marrow and Embryonal Tumors to Facilitate Immunotherapeutic Approaches in Pediatric Malignancies

    Kruchen, A., Johann, P-D., Rekowski, L. & Müller, I., 03.03.2023, In: CURR ISSUES MOL BIOL. 45, 3, p. 2121-2135 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  65. Outcomes of Childhood Noninfant Acute Lymphoblastic Leukemia With 11q23/KMT2A Rearrangements in a Modern Therapy Era: A Retrospective International Study

    Attarbaschi, A., Möricke, A., Harrison, C. J., Mann, G., Baruchel, A., De Moerloose, B., Conter, V., Devidas, M., Elitzur, S., Escherich, G., Hunger, S. P., Horibe, K., Manabe, A., Loh, M. L., Pieters, R., Schmiegelow, K., Silverman, L. B., Stary, J., Vora, A., Pui, C-H., Schrappe, M. & Zimmermann, M., 01.03.2023, In: J CLIN ONCOL. 41, 7, p. 1404-1422 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  66. Surgical Experience Affects the Outcome of Central Venous Access Catheter Implantation in Children: A Retrospective Cohort Study

    Fritsch, L-M., Le, M., Elrod, J., Wössmann, W., Vincent, D., Reinshagen, K. & Boettcher, M., 01.03.2023, In: J PEDIAT HEMATOL ONC. 45, 2, p. 57-62 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  67. Diagnosis and management of ALK-positive anaplastic large cell lymphoma in children and adolescents

    Rigaud, C., Knörr, F., Brugières, L. & Woessmann, W., 03.2023, In: BEST PRACT RES CL HA. 36, 1, p. 101444

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  68. Improving outcomes of childhood and young adult non-Hodgkin lymphoma: 25 years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma

    Beishuizen, A., Mellgren, K., Andrés, M., Auperin, A., Bacon, C. M., Bomken, S., Burke, G. A. A., Burkhardt, B., Brugieres, L., Chiang, A. K. S., Damm-Welk, C., d'Amore, E., Horibe, K., Kabickova, E., Khanam, T., Kontny, U., Klapper, W., Lamant, L., Le Deley, M-C., Loeffen, J., Macintyre, E., Mann, G., Meyer-Wentrup, F., Michgehl, U., Minard-Colin, V., Mussolin, L., Oschlies, I., Patte, C., Pillon, M., Reiter, A., Rigaud, C., Roncery, L., Salaverria, I., Simonitsch-Klupp, I., Uyttebroeck, A., Verdu-Amoros, J., Williams, D., Woessmann, W., Wotherspoon, A., Wrobel, G., Zimmermann, M., Attarbaschi, A., Turner, S. D. & European Intergroup for Childhood Non-Hodgkin Lymphoma, 03.2023, In: LANCET HAEMATOL. 10, 3, p. e213-e224 12 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  69. Single-cell gene regulatory network prediction by explainable AI

    Keyl, P., Bischoff, P., Dernbach, G., Bockmayr, M., Fritz, R., Horst, D., Blüthgen, N., Montavon, G., Müller, K-R. & Klauschen, F., 28.02.2023, In: NUCLEIC ACIDS RES. 51, 4, p. e20

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  70. EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy

    Elitzur, S., Vora, A., Burkhardt, B., Inaba, H., Attarbaschi, A., Baruchel, A., Escherich, G., Gibson, B. E., Liu, H-C., Loh, M. L., Moorman, A. V., Möricke, A., Pieters, R., Uyttebroeck, A., Baird, S., Bartram, J., Barzilai-Birenboim, S., Batra, S., Ben-Harosh, M., Bertrand, Y., Buitenkamp, T., Caldwell, K., Drut, R., Geerlinks, A. V., Gilad, G., Grainger, J., Haouy, S., Heaney, N. B., Huang, M., Ingham, D., Krenova, Z., Kuhlen, M., Lehrnbecher, T., Manabe, A., Niggli, F., Paris, C., Revel-Vilk, S., Rohrlich, P., Sinno, M. G., Szczepanski, T., Tamesberger, M., Warrier, R., Wolfl, M., Nirel, R., Izraeli, S., Borkhardt, A. & Schmiegelow, K., 16.02.2023, In: BLOOD. 141, 7, p. 743-755 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  71. DNA methylation subclasses predict the benefit from gross total tumor resection in IDH-wildtype glioblastoma patients

    Drexler, R., Schüller, U., Eckhardt, A., Filipski, K., Hartung, T. I., Harter, P. N., Divé, I., Forster, M-T., Czabanka, M., Jelgersma, C., Onken, J., Vajkoczy, P., Capper, D., Siewert, C., Sauvigny, T., Lamszus, K., Westphal, M., Dührsen, L. & Ricklefs, F. L., 14.02.2023, In: NEURO-ONCOLOGY. 25, 2, p. 315-325 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  72. Frequency and prognostic implications of KMT2A rearrangements in children with precursor B-cell lymphoma

    Au-Yeung, R. K. H., Padilla, L. A., Zimmermann, M., Reinke, S., Oschlies, I., Escherich, G., Woessmann, W., Burkhardt, B. & Klapper, W., 02.2023, In: LEUKEMIA. 37, 2, p. 488-491 4 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  73. Unveiling the identities of null cell tumours: Epigenomics corroborate subtle histological cues in pituitary neuroendocrine tumour/adenoma classification

    Dottermusch, M., Schüller, U., Hagel, C. & Saeger, W., 02.2023, In: NEUROPATH APPL NEURO. 49, 1, p. e12870

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  74. G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells

    Cetin, M. H., Rieckmann, T., Hoffer, K., Riepen, B., Christiansen, S., Gatzemeier, F., Feyerabend, S., Schoof, M., Schüller, U., Petersen, C., Mynarek, M., Rothkamm, K., Kriegs, M. & Struve, N., 29.01.2023, In: RADIAT ONCOL. 18, 1, 19.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  75. Germ Cell Maintenance and Sustained Testosterone and Precursor Hormone Production in Human Prepubertal Testis Organ Culture with Tissues from Boys 7 Years+ under Conditions from Adult Testicular Tissue

    Aden, N. L., Bleeke, M., Kordes, U., Brunne, B., Holstermann, B., Biemann, R., Ceglarek, U., Soave, A., Salzbrunn, A., Schneider, S. & Kopylow, K. V., 26.01.2023, In: CELLS-BASEL. 12, 3, 415.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  76. Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level

    Voß, H., Godbole, S., Schlumbohm, S., Schumann, Y., Peng, B., Mynarek, M., Rutkowski, S. J., Dottermusch, M., Dorostkar, M. M., Koshunov, A., Mair, T., Pfister, S. M., Neumann, P., Hartmann, C., Weis, J., Liesche-Starnecker, F., Guan, Y., Schlüter, H., Schüller, U., Krisp, C. & Neumann, J., 09.01.2023, In: bioRxiv. 2023

    Research output: SCORING: Contribution to journalPreprintResearch

  77. Allogeneic haematopoietic cell transplant in patients with relapsed/refractory anaplastic large cell lymphoma - Response

    Knörr, F. & Woessmann, W., 01.2023, In: BRIT J HAEMATOL. 200, 1, p. 107-108 2 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  78. Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification

    Keck, M-K., Sill, M., Wittmann, A., Joshi, P., Stichel, D., Beck, P., Okonechnikow, K., Sievers, P., Wefers, A. K., Roncaroli, F., Avula, S., McCabe, M. G., Hayden, J. T., Wesseling, P., Øra, I., Nistér, M., Kranendonk, M. E. G., Tops, B. B. J., Zapotocky, M., Zamecnik, J., Vasiljevic, A., Fenouil, T., Meyronet, D., von Hoff, K., Schüller, U., Loiseau, H., Figarella-Branger, D., Kramm, C. M., Sturm, D., Scheie, D., Rauramaa, T., Pesola, J., Gojo, J., Haberler, C., Brandner, S., Jacques, T., Sexton Oates, A., Saffery, R., Koscielniak, E., Baker, S. J., Yip, S., Snuderl, M., Ud Din, N., Samuel, D., Schramm, K., Blattner-Johnson, M., Selt, F., Ecker, J., Milde, T., von Deimling, A., Korshunov, A., Perry, A., Pfister, S. M., Sahm, F., Solomon, D. A. & Jones, D. T. W., 01.2023, In: ACTA NEUROPATHOL. 145, 1, p. 49-69 21 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  79. Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts

    Mynarek, M., Obrecht, D., Sill, M., Sturm, D., Kloth-Stachnau, K., Selt, F., Ecker, J., von Hoff, K., Juhnke, B-O., Goschzik, T., Pietsch, T., Bockmayr, M., Kool, M., von Deimling, A., Witt, O., Schüller, U., Benesch, M., Gerber, N. U., Sahm, F., Jones, D. T. W., Korshunov, A., Pfister, S. M., Rutkowski, S. & Milde, T., 01.2023, In: ACTA NEUROPATHOL. 145, 1, p. 97-112 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  80. Left ventricular diastolic filling patterns in competitive triathletes with and without myocardial fibrosis by cardiac magnetic resonance time-volume analysis

    Chen, H., Jungesblut, J., Saering, D., Muellerleile, K., Beitzen-Heineke, A., Harms, P., Erley, J., Schoennagel, B., Schneider, J. N., Cavus, E., Fischer, R., Lund, G. K., Adam, G. & Tahir, E., 01.2023, In: EUR J RADIOL. 158, 110615.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  81. Long-Term Antibody Response to SARS-CoV-2 in Children

    Dunay, G. A., Barroso, M., Woidy, M., Danecka, M. K., Engels, G., Hermann, K., Neumann, F. S., Paul, K., Beime, J., Escherich, G., Fehse, K., Grinstein, L., Haniel, F., Haupt, L. J., Hecher, L., Kehl, T., Kemen, C., Kemper, M. J., Kobbe, R., Kohl, A., Klokow, T., Nörz, D., Olfe, J., Schlenker, F., Schmiesing, J., Schrum, J., Sibbertsen, F., Stock, P., Tiede, S., Vettorazzi, E., Zazara, D. E., Zapf, A., Lütgehetmann, M., Oh, J., Mir, T. S., Muntau, A. C., Gersting, S. W. & C19.CHILD Study Group, 01.2023, In: J CLIN IMMUNOL. 43, 1, p. 46-56 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  82. A multi-institutional retrospective pooled outcome analysis of molecularly annotated pediatric supratentorial ZFTA-fused ependymoma

    Ng, C. H., Obrecht, D., Wells, O., Zapotocky, M., Sumerauer, D., Coltin, H., Khuong-Quang, D-A., Eisenstat, D. D., Kinross, K. M., White, C. L., Algar, E. M., Luck, A., Witt, H., Schüller, U., Mynarek, M., Pietsch, T., Gerber, N. U., Benesch, M., Warmuth-Metz, M., Kortmann, R., Bison, B., Taylor, M. D., Rutkowski, S., Pfister, S. M., Jones, D. T., Gottardo, N. G., von Hoff, K., Pajtler, K. W., Ramaswamy, V. & Hansford, J. R., 2023, In: NEURO-ONCOL ADV. 5, 1, p. vdad057

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  83. Effects of a Pretend Play Intervention on Health-Related Quality of Life in Children With Cancer: A Swedish-German Study

    Witt, S., Quitmann, J., Höglund, A. T., Russ, S., Kaman, A., Escherich, G. & Frygner-Holm, S., 2023, In: J PEDIAT HEMAT ONC N. 40, 3, p. 158-169 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  84. Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A)

    Brauer, N., Maruta, Y., Lisci, M., Strege, K., Oschlies, I., Nakamura, H., Böhm, S., Lehmberg, K., Brandhoff, L., Ehl, S., Parvaneh, N., Klapper, W., Fukuda, M., Griffiths, G. M., Hennies, H. C., Niehues, T. & Ammann, S., 2023, In: FRONT IMMUNOL. 14, p. 1151166

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  85. Integrating copy number data of 64 iAMP21 BCP-ALL patients narrows the common region of amplification to 1.57 Mb

    Hormann, F. M., Hoogkamer, A. Q., Boeree, A., Sonneveld, E., Escherich, G., den Boer, M. L. & Boer, J. M., 2023, In: FRONT ONCOL. 13, p. 1128560

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  86. 2022
  87. Differential Diagnosis of Hyperferritinemia in Critically Ill Patients

    Schuster, F. S., Nyvlt, P., Heeren, P., Spies, C., Adam, M. F., Schenk, T., Brunkhorst, F. M., Janka, G., La Rosée, P., Lachmann, C. & Lachmann, G., 27.12.2022, In: J CLIN MED. 12, 1, 192.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  88. Dormant SOX9-positive cells facilitate MYC-driven recurrence of medulloblastoma

    Borgenvik, A., Holmberg, K. O., Bolin, S., Zhao, M., Savov, V., Rosén, G., Hutter, S., Garancher, A., Suryo Rahmanto, A., Bergström, T., Olsen, T. K., Mainwaring, O. J., Sattanino, D., Verbaan, A. D., Rusert, J. M., Sundstrom, A., Ballester Bravo, M., Dang, Y., Wenz, A. S., Richardson, S., Fotaki, G., Hill, R. M., Dubuc, A. M., Kalushkova, A., Remke, M., Cancer, M., Jernberg-Wiklund, H., Giraud, G., Chen, X., Taylor, M. D., Sangfelt, O., Clifford, S. C., Schüller, U., Wechsler-Reya, R. J., Weishaupt, H. & Swartling, F. J., 16.12.2022, In: CANCER RES. 82, 24, p. 4586-4603 18 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  89. Laparoscopic Subtotal Splenectomy in Children and Adolescents With Spherocytosis

    Le, M., Grosse, R., Elrod, J., Klinke, M., Reinshagen, K. & Boettcher, M., 09.12.2022, In: DTSCH ARZTEBL INT. 119, 49, p. 848-849 2 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  90. Immune Ablation and Stem Cell Rescue in Two Pediatric Patients with Progressive Severe Chronic Graft-Versus-Host Disease

    Kloehn, J., Kruchen, A., Schütze, K., Wustrau, K., Schrum, J. & Müller, I., 06.12.2022, In: INT J MOL SCI. 23, 23, 15403.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  91. Amsacrine combined with etoposide and methylprednisolone is a feasible and safe component in first-line intensified treatment of pediatric patients with high-risk acute lymphoblastic leukemia in CoALL08-09 trial

    Mezger, K., Ebert, S., Muhle, H. E., Stadt, U. Z., Borkhardt, A., Dilloo, D., Faber, J., Feuchtinger, T., Imschweiler, T., Jorch, N., Pekrun, A., Schmid, I., Schramm, F., Zimmermann, M., Horstmann, M. A. & Escherich, G., 12.2022, In: PEDIATR BLOOD CANCER. 69, 12, e29997.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  92. Essential medicines for childhood cancer in Europe: a pan-European, systematic analysis by SIOPE

    Otth, M., Brack, E., Kearns, P. R., Kozhaeva, O., Ocokoljic, M., Schoot, R. A., Vassal, G. & Essential Medicines Group, 12.2022, In: LANCET ONCOL. 23, 12, p. 1537-1546 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  93. Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas

    Goschzik, T., Mynarek, M., Doerner, E., Schenk, A., Spier, I., Warmuth-Metz, M., Bison, B., Obrecht, D., Struve, N., Kortmann, R-D., Schmid, M., Aretz, S., Rutkowski, S. & Pietsch, T., 12.2022, In: ACTA NEUROPATHOL. 144, 6, p. 1143-1156 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  94. Structure and dynamics of the von Willebrand Factor C6 domain

    Chen, P-C., Kutzki, F., Mojzisch, A., Simon, B., Xu, E-R., Aponte-Santamaría, C., Horny, K., Jeffries, C., Schneppenheim, R., Wilmanns, M., Brehm, M. A., Gräter, F. & Hennig, J., 12.2022, In: J STRUCT BIOL. 214, 4, 107923.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  95. DNA methylation-based classification of sinonasal tumors

    Jurmeister, P., Glöß, S., Roller, R., Leitheiser, M., Schmid, S., Mochmann, L. H., Payá Capilla, E., Fritz, R., Dittmayer, C., Friedrich, C., Thieme, A., Keyl, P., Jarosch, A., Schallenberg, S., Bläker, H., Hoffmann, I., Vollbrecht, C., Lehmann, A., Hummel, M., Heim, D., Haji, M., Harter, P., Englert, B., Frank, S., Hench, J., Paulus, W., Hasselblatt, M., Hartmann, W., Dohmen, H., Keber, U., Jank, P., Denkert, C., Stadelmann, C., Bremmer, F., Richter, A., Wefers, A., Ribbat-Idel, J., Perner, S., Idel, C., Chiariotti, L., Della Monica, R., Marinelli, A., Schüller, U., Bockmayr, M., Liu, J., Lund, V. J., Forster, M., Lechner, M., Lorenzo-Guerra, S. L., Hermsen, M., Johann, P. D., Agaimy, A., Seegerer, P., Koch, A., Heppner, F., Pfister, S. M., Jones, D. T. W., Sill, M., von Deimling, A., Snuderl, M., Müller, K-R., Forgó, E., Howitt, B. E., Mertins, P., Klauschen, F. & Capper, D., 28.11.2022, In: NAT COMMUN. 13, 1, 7148.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  96. Proton Beam Therapy for Pediatric Tumors of the Central Nervous System-Experiences of Clinical Outcome and Feasibility from the KiProReg Study

    Peters, S., Frisch, S., Stock, A., Merta, J., Bäumer, C., Blase, C., Schuermann, E., Tippelt, S., Bison, B., Frühwald, M., Rutkowski, S., Fleischhack, G. & Timmermann, B., 28.11.2022, In: CANCERS. 14, 23, 5863.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  97. DNA Methylation subclass Receptor Tyrosine Kinase II (RTK II) is predictive for seizure development in glioblastoma patients

    Ricklefs, F. L., Drexler, R., Wollmann, K., Eckhardt, A., Heiland, D. H., Sauvigny, T., Maire, C., Lamszus, K., Westphal, M., Schüller, U. & Dührsen, L., 02.11.2022, In: NEURO-ONCOLOGY. 24, 11, p. 1886-1897 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  98. Aktualisierte AWMF Leitlinie über die Diagnostik und Therapie der akuten lymphoblastische Leukämie im Kindesalter

    Escherich, G. & Schrappe, M., 11.2022, In: KLIN PADIATR. 234, 6, p. 363-367 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  99. Coping with Diffuse Intrinsic Pontine Glioma in Children - Findings from an Interview Study on Bereaved Parents

    Radlanski, K., Hartwig, M. & Kordes, U., 11.2022, In: KLIN PADIATR. 234, 6, p. 374-381 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  100. Genetic and epigenetic profiling identifies two distinct classes of spinal meningiomas

    Ricklefs, F. L., Fita, K., Mohme, M., Mawrin, C., Rahmanzade, R., Sahm, F., Dührsen, L., Göbel, C., Lamszus, K., Westphal, M., Schüller, U. & Eicker, S-O., 11.2022, In: ACTA NEUROPATHOL. 144, 5, p. 1057-1059 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  101. Incidence of subsequent malignancies after total body irradiation-based allogeneic HSCT in children with ALL - long-term follow-up from the prospective ALL-SCT 2003 trial

    Eichinger, A., Poetschger, U., Glogova, E., Bader, P., Basu, O., Beier, R., Burkhardt, B., Classen, C-F., Claviez, A., Corbacioglu, S., Deubzer, H. E., Greil, J., Gruhn, B., Güngör, T., Kafa, K., Kühl, J-S., Lang, P., Lange, B. S., Meisel, R., Müller, I., Sauer, M. G., Schlegel, P-G., Schulz, A., Stachel, D., Strahm, B., Wawer, A., Peters, C. & Albert, M. H., 11.2022, In: LEUKEMIA. 36, 11, p. 2567-2576 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  102. Thirteen-month-old girl with hyporegenerative macrocytic anemia due to Brown-Vialetto-Van Laere syndrome 2

    Naami, N., Borkhardt, A., Yoshimi, A., Grinstein, L. & Escherich, G., 11.2022, In: AM J HEMATOL. 97, 11, p. 1495-1496 2 p.

    Research output: SCORING: Contribution to journalEditorialResearch

  103. Comprehensive profiling of myxopapillary ependymomas identifies a distinct molecular subtype with relapsing disease

    Bockmayr, M., Harnisch, K., Pohl, L. C., Schweizer, L., Mohme, T., Körner, M., Alawi, M., Suwala, A. K., Dorostkar, M. M., Monoranu, C. M., Hasselblatt, M., Wefers, A. K., Capper, D., Hench, J., Frank, S., Richardson, T. E., Tran, I., Liu, E., Snuderl, M., Engertsberger, L., Benesch, M., von Deimling, A., Obrecht, D., Mynarek, M., Rutkowski, S., Glatzel, M., Neumann, J. E. & Schüller, U., 03.10.2022, In: NEURO-ONCOLOGY. 24, 10, p. 1689-1699 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  104. MR Imaging and Clinical Characteristics of Diffuse Glioneuronal Tumor with Oligodendroglioma-like Features and Nuclear Clusters

    Benesch, M., Perwein, T., Apfaltrer, G., Langer, T., Neumann, A., Brecht, I. B., Schuhmann, M. U., Cario, H., Frühwald, M. C., Vollert, K., van Buiren, M., Deng, M. Y., Seitz, A., Haberler, C., Mynarek, M., Kramm, C., Sahm, F., Robe, P. A., Dankbaar, J. W., Hoff, K. V., Warmuth-Metz, M. & Bison, B., 10.2022, In: AM J NEURORADIOL. 43, 10, p. 1523-1529 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  105. Osteonekrosen – gravierende Therapiefolge bei akuter lymphoblastischer Leukämie

    Kuhlen, M., Kunstreich, M., Gökbuget, N. & Escherich, G., 10.2022, In: ORTHOPADIE. 51, 10, p. 792-799 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  106. A conformational transition of the D'D3 domain primes von Willebrand factor for multimerization

    Gruber, S., Löf, A., Hausch, A., Kutzki, F., Jöhr, R., Obser, T., König, G., Schneppenheim, R., Aponte-Santamaría, C., Gräter, F., Brehm, M. A., Benoit, M. & Lipfert, J., 13.09.2022, In: BLOOD ADV. 6, 17, p. 5198-5209 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  107. SMARCB1-deficient and SMARCA4-deficient Malignant Brain Tumors With Complex Copy Number Alterations and TP53 Mutations May Represent the First Clinical Manifestation of Li-Fraumeni Syndrome

    Hasselblatt, M., Thomas, C., Federico, A., Nemes, K., Johann, P. D., Bison, B., Bens, S., Dahlum, S., Kordes, U., Redlich, A., Lessel, L., Pajtler, K. W., Mawrin, C., Schüller, U., Nolte, K., Kramm, C. M., Hinz, F., Sahm, F., Giannini, C., Penkert, J., Kratz, C. P., Pfister, S. M., Siebert, R., Paulus, W., Kool, M. & Frühwald, M. C., 01.09.2022, In: AM J SURG PATHOL. 46, 9, p. 1277-1283 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  108. Artificial intelligence and pathology: From principles to practice and future applications in histomorphology and molecular profiling

    Stenzinger, A., Alber, M., Allgäuer, M., Jurmeister, P., Bockmayr, M., Budczies, J., Lennerz, J., Eschrich, J., Kazdal, D., Schirmacher, P., Wagner, A. H., Tacke, F., Capper, D., Müller, K-R. & Klauschen, F., 09.2022, In: SEMIN CANCER BIOL. 84, p. 129-143 15 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  109. Characterization of IG-MYC-breakpoints and their application for quantitative minimal disease monitoring in high-risk pediatric Burkitt-lymphoma and -leukemia

    Möker, P., Zur Stadt, U., Zimmermann, M., Alawi, M., Mueller, S., Finger, J., Knörr, F., Riquelme, A., Oschlies, I., Klapper, W., Bradtke, J., Burkhardt, B., Woessmann, W. & Damm-Welk, C., 09.2022, In: LEUKEMIA. 36, 9, p. 2343-2346 4 p.

    Research output: SCORING: Contribution to journalLetterResearch

  110. Global effort to evacuate Ukrainian children with cancer and blood disorders who have been affected by war

    Agulnik, A., Kizyma, R., Salek, M., Wlodarski, M. W., Pogorelyy, M., Oszer, A., Yakimkova, T., Nogovitsyna, Y., Dutkiewicz, M., Dalle, J-H., Dirksen, U., Eggert, A., Fernández-Teijeiro, A., Greiner, J., Kraal, K., Mueller, A., Sramkova, L., Zecca, M., Wise, P. H., Mlynarski, W. & SAFER Ukraine Collaborative, 09.2022, In: LANCET HAEMATOL. 9, 9, p. e645-e647

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  111. PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma

    Garces de Los Fayos Alonso, I., Zujo, L., Wiest, I., Kodajova, P., Timelthaler, G., Edtmayer, S., Zrimšek, M., Kollmann, S., Giordano, C., Kothmayer, M., Neubauer, H. A., Dey, S., Schlederer, M., Schmalzbauer, B. S., Limberger, T., Probst, C., Pusch, O., Högler, S., Tangermann, S., Merkel, O., Schiefer, A. I., Kornauth, C., Prutsch, N., Zimmerman, M., Abraham, B., Anagnostopoulos, J., Quintanilla-Martinez, L., Mathas, S., Wolf, P., Stoiber, D., Staber, P. B., Egger, G., Klapper, W., Woessmann, W., Look, T. A., Gunning, P., Turner, S. D., Moriggl, R., Lagger, S. & Kenner, L., 31.08.2022, In: MOL CANCER. 21, 1, p. 172

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  112. Genotype-phenotype associations within the Li-Fraumeni spectrum: a report from the German Registry

    Penkert, J., Strüwe, F. J., Dutzmann, C. M., Doergeloh, B. B., Montellier, E., Freycon, C., Keymling, M., Schlemmer, H-P., Sänger, B., Hoffmann, B., Gerasimov, T., Blattmann, C., Fetscher, S., Frühwald, M., Hettmer, S., Kordes, U., Ridola, V., Kroiss Benninger, S., Mastronuzzi, A., Schott, S., Nees, J., Prokop, A., Redlich, A., Seidel, M. G., Zimmermann, S., Pajtler, K. W., Pfister, S. M., Hainaut, P. & Kratz, C. P., 16.08.2022, In: J HEMATOL ONCOL. 15, 1, 107.

    Research output: SCORING: Contribution to journalLetterResearch

  113. ALK inhibition as a salvage therapy for a relapsed unclassifiable sarcomatous CNS tumor with EML4/ALK fusion in an infant

    Holsten, T., Bronsema, A., Sturm, D., Sahm, F., Rutkowski, S., Ulrich, S., Wößmann, W. & Kordes, U. R., 08.2022, In: PEDIATR BLOOD CANCER. 69, 8, e29594.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  114. Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high-hyperdiploid B-cell acute lymphoblastic leukemia

    Ramos-Muntada, M., Trincado, J. L., Blanco, J., Bueno, C., Rodríguez-Cortez, V. C., Bataller, A., López-Millán, B., Schwab, C., Ortega, M., Velasco, P., Blanco, M. L., Nomdedeu, J., Ramírez-Orellana, M., Minguela, A., Fuster, J. L., Cuatrecasas, E., Camós, M., Ballerini, P., Escherich, G., Boer, J., DenBoer, M., Hernández-Rivas, J. M., Calasanz, M. J., Cazzaniga, G., Harrison, C. J., Menéndez, P. & Molina, O., 08.2022, In: MOL ONCOL. 16, 16, p. 2899-2919 21 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  115. Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development

    Li, Q., Han, Z., Singh, N., Terré, B., Fame, R. M., Arif, U., Page, T. D., Zahran, T., Abdeltawab, A., Huang, Y., Cao, P., Wang, J., Lu, H., Lidov, H. G. W., Surendran, K., Wu, L., Virga, J. Q., Zhao, Y-T., Ulrich, S., Wechsler-Reya, R. J., Lehtinen, M. K., Roy, S., Liu, Z., Stracker, T. H. & Zhao, H., 08.2022, In: CELL DEATH DIFFER. 29, 8, p. 1596-1610 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  116. Fear of progression in parents of childhood cancer survivors: prevalence and associated factors

    Peikert, M. L., Inhestern, L., Krauth, K. A., Escherich, G., Rutkowski, S., Kandels, D., Schiekiera, L. J. & Bergelt, C., 08.2022, In: J CANCER SURVIV. 16, 4, p. 823-833 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  117. Gene expression profiling of Group 3 medulloblastomas defines a clinically tractable stratification based on KIRREL2 expression

    Korshunov, A., Okonechnikov, K., Stichel, D., Schrimpf, D., Delaidelli, A., Tonn, S., Mynarek, M., Sievers, P., Sahm, F., Jones, D. T. W., von Deimling, A., Pfister, S. M. & Kool, M., 08.2022, In: ACTA NEUROPATHOL. 144, 2, p. 339-352 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  118. Reduced adhesion of aged intestinal stem cells contributes to an accelerated clonal drift

    Hageb, A., Thalheim, T., Nattamai, K. J., Möhrle, B., Saçma, M., Sakk, V., Thielecke, L., Kerstin, C., Grandy, C., Port, F., Gottschalk, K-E., Mallm, J-P., Glauche, I., Galle, J., Mulaw, M. A. & Geiger, H., 08.2022, In: LIFE SCI ALLIANCE. 5, 8, e202201408.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  119. Persistence of MERS-CoV-spike-specific B cells and antibodies after late third immunization with the MVA-MERS-S vaccine

    Weskamm, L. M., Fathi, A., Raadsen, M. P., Mykytyn, A. Z., Koch, T., Spohn, M., Friedrich, M., MVA-MERS-S Study Group, Haagmans, B. L., Becker, S., Sutter, G., Dahlke, C. & Addo, M. M., 19.07.2022, In: CELL REP MED. 3, 7, 100685.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  120. Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age

    Burkhardt, B., Michgehl, U., Rohde, J., Erdmann, T., Berning, P., Reutter, K., Rohde, M., Borkhardt, A., Burmeister, T., Dave, S., Tzankov, A., Dugas, M., Sandmann, S., Fend, F., Finger, J., Mueller, S., Gökbuget, N., Haferlach, T., Kern, W., Hartmann, W., Klapper, W., Oschlies, I., Richter, J., Kontny, U., Lutz, M., Maecker-Kolhoff, B., Ott, G., Rosenwald, A., Siebert, R., von Stackelberg, A., Strahm, B., Woessmann, W., Zimmermann, M., Zapukhlyak, M., Grau, M. & Lenz, G., 06.07.2022, In: NAT COMMUN. 13, 1, 3881.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  121. Evaluation of dose, volume and outcome in children with localized, intracranial ependymoma treated with proton therapy within the prospective KiProReg Study

    Peters, S., Merta, J., Schmidt, L., Jazmati, D., Kramer, P. H., Blase, C., Tippelt, S., Fleischhack, G., Stock, A., Bison, B., Rutkowski, S., Pietsch, T., Kortmann, R. D. & Timmermann, B., 01.07.2022, In: NEURO-ONCOLOGY. 24, 7, p. 1193-1202 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  122. Pediatric T-ALL type-1 and type-2 relapses develop along distinct pathways of clonal evolution

    Richter-Pechańska, P., Kunz, J. B., Rausch, T., Erarslan-Uysal, B., Bornhauser, B., Frismantas, V., Assenov, Y., Zimmermann, M., Happich, M., von Knebel-Doeberitz, C., von Neuhoff, N., Köhler, R., Stanulla, M., Schrappe, M., Cario, G., Escherich, G., Kirschner-Schwabe, R., Eckert, C., Avigad, S., Pfister, S. M., Muckenthaler, M. U., Bourquin, J-P., Korbel, J. O. & Kulozik, A. E., 07.2022, In: LEUKEMIA. 36, 7, p. 1759-1768 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  123. Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond

    Kresbach, C., Neyazi, S. & Schüller, U., 07.2022, In: BRAIN PATHOL. 32, 4, e13068.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  124. Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma

    Ravi, V. M., Will, P., Kueckelhaus, J., Sun, N., Joseph, K., Salié, H., Vollmer, L., Kuliesiute, U., von Ehr, J., Benotmane, J. K., Neidert, N., Follo, M., Scherer, F., Goeldner, J. M., Behringer, S. P., Franco, P., Khiat, M., Zhang, J., Hofmann, U. G., Fung, C., Ricklefs, F. L., Lamszus, K., Boerries, M., Ku, M., Beck, J., Sankowski, R., Schwabenland, M., Prinz, M., Schüller, U., Killmer, S., Bengsch, B., Walch, A. K., Delev, D., Schnell, O. & Heiland, D. H., 13.06.2022, In: CANCER CELL. 40, 6, p. 639-655.e13

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  125. Patient-level proteomic network prediction by explainable artificial intelligence

    Keyl, P., Michael, B., Heim, D., Dernbach, G., Montavon, G., Müller, K-R. & Klauschen, F., 07.06.2022, In: NPJ PRECIS ONCOL. 6, 1, 35.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  126. ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance

    Federico, A., Thomas, C., Miskiewicz, K., Woltering, N., Zin, F., Nemes, K., Bison, B., Johann, P. D., Hawes, D., Bens, S., Kordes, U., Albrecht, S., Dohmen, H., Hauser, P., Keyvani, K., van Landeghem, F. K. H., Lund, E. L., Scheie, D., Mawrin, C., Monoranu, C-M., Parm Ulhøi, B., Pietsch, T., Reinhard, H., Riemenschneider, M. J., Sehested, A., Sumerauer, D., Siebert, R., Paulus, W., Frühwald, M. C., Kool, M. & Hasselblatt, M., 06.2022, In: ACTA NEUROPATHOL. 143, 6, p. 697-711 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  127. Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC

    Hasselblatt, M., Thomas, C., Federico, A., Bens, S., Hellström, M., Casar-Borota, O., Kordes, U., Neumann, J. E., Dottermusch, M., Rodriguez, F. J., Lo, A. C., Cheng, S., Hendson, G., Hukin, J., Hartmann, C., Koch, A., Capper, D., Siebert, R., Paulus, W., Nemes, K., Johann, P. D., Frühwald, M. C. & Kool, M., 06.2022, In: NEUROPATH APPL NEURO. 48, 4, p. e12797 e12797.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  128. MODL-03. Establishment of intraventricular Shh inhibition as a therapeutic option for young patients with medulloblastoma

    Kresbach, C., Schoof, M., Holst, L., Leven, T., Yorgan, T. A., Wrzeszcz, A., Rutkowski, S. J. & Schüller, U., 06.2022, In: NEURO-ONCOLOGY. 24, S1, p. i168

    Research output: SCORING: Contribution to journalConference abstract in journalResearchpeer-review

  129. Long noncoding RNAs as regulators of pediatric acute myeloid leukemia

    Neyazi, S., Ng, M., Heckl, D. & Klusmann, J-H., 20.05.2022, In: Molecular and cellular pediatrics. 9, 1, 10.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  130. Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol

    Toksvang, L. N., Als-Nielsen, B., Bacon, C., Bertasiute, R., Duarte, X., Escherich, G., Helgadottir, E. A., Johannsdottir, I. R., Jónsson, Ó. G., Kozlowski, P., Langenskjöld, C., Lepik, K., Niinimäki, R., Overgaard, U. M., Punab, M., Räty, R., Segers, H., van der Sluis, I., Smith, O. P., Strullu, M., Vaitkevičienė, G., Wik, H. S., Heyman, M. & Schmiegelow, K., 02.05.2022, In: BMC CANCER. 22, 1, 483.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  131. Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acute Lymphoblastic Leukemia Study Group

    Escherich, G., Zur Stadt, U., Borkhardt, A., Dilloo, D., Faber, J., Feuchtinger, T., Imschweiler, T., Jorch, N., Pekrun, A., Schmid, I., Schramm, F., Spohn, M., Zimmermann, M. & Horstmann, M. A., 01.05.2022, In: HAEMATOLOGICA. 107, 5, p. 1026-1033 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  132. Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults

    Hines, M. R., von Bahr Greenwood, T., Beutel, G., Beutel, K., Hays, J. A., Horne, A., Janka, G., Jordan, M. B., van Laar, J. A. M., Lachmann, G., Lehmberg, K., Machowicz, R., Miettunen, P., La Rosée, P., Shakoory, B., Zinter, M. S. & Henter, J-I., 01.05.2022, In: CRIT CARE MED. 50, 5, p. 860-872 13 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  133. Does the Y chromosome play a role for outcome in childhood acute lymphoblastic leukemia?

    Conter, V., Schrappe, M. & Escherich, G., 01.05.2022, In: CANCER-AM CANCER SOC. 128, 9, p. 1727-1729 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  134. Allogeneic hematopoietic stem cell transplantation for adult HLH: a retrospective study by the chronic malignancies and inborn errors working parties of EBMT

    Machowicz, R., Suarez, F., Wiktor-Jedrzejczak, W., Eikema, D-J., de Wreede, L. C., Blok, H-J., Isaksson, C., Einsele, H., Poiré, X., van Dorp, S., Nikolousis, E., Johansson, J-E., Kobbe, G., Zecca, M., Arnold, R., Gerbitz, A., Finke, J., Díez-Martín, J. L., Bonifazi, F., McQuaker, G., Lenhoff, S., Rohrlich, P-S., Theobald, M., Ljungman, P., Collin, M., Albert, M. H., Ehninger, G., Carlson, K., Halaburda, K., Lehmberg, K., Schönland, S., Yakoub-Agha, I., Gennery, A. R., Lankester, A. C. & Kröger, N., 05.2022, In: BONE MARROW TRANSPL. 57, 5, p. 817-823 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  135. Comparison of single copy gene‑based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19‑directed CAR T cells in treated patients

    Schubert, M-L., Berger, C., Kunz, A., Schmitt, A., Badbaran, A., Neuber, B., Zeschke, S., Wang, L., Riecken, K., Hückelhoven-Krauss, A., Müller, I., Müller-Tidow, C., Dreger, P., Kröger, N., Ayuk, F. A., Schmitt, M. & Fehse, B., 05.2022, In: INT J ONCOL. 60, 5, 48.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  136. Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population

    Nemes, K., Johann, P. D., Steinbügl, M., Gruhle, M., Bens, S., Kachanov, D., Teleshova, M., Hauser, P., Simon, T., Tippelt, S., Eberl, W., Chada, M., Lopez, V. S-M., Grigull, L., Hernáiz-Driever, P., Eyrich, M., Pears, J., Milde, T., Reinhard, H., Leipold, A., van de Wetering, M., Gil-da-Costa, M. J., Ebetsberger-Dachs, G., Kerl, K., Lemmer, A., Boztug, H., Furtwängler, R., Kordes, U., Vokuhl, C., Hasselblatt, M., Bison, B., Kröncke, T., Melchior, P., Timmermann, B., Gerss, J., Siebert, R. & Frühwald, M. C., 27.04.2022, In: CANCERS. 14, 9, 2185.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  137. Children with cancer and their families after active treatment: analyses of biopsychosocial needs and implications for healthcare - a study protocol

    Inhestern, L., Paul, V., Winzig, J., Rutkowski, S., Escherich, G. & Bergelt, C., 05.04.2022, In: BMJ OPEN. 12, 4, p. e055633

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  138. Can Machine Learning Models Predict Asparaginase-associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia

    Nielsen, R. L., Wolthers, B. O., Helenius, M., Albertsen, B. K., Clemmensen, L., Nielsen, K., Kanerva, J., Niinimäki, R., Frandsen, T. L., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Aytan-Aktug, D., Liu, H-C., Möricke, A., Samarasinghe, S., van der Sluis, I. M., Stanulla, M., Tulstrup, M., Yadav, R., Zapotocka, E., Schmiegelow, K. & Gupta, R., 01.04.2022, In: J PEDIAT HEMATOL ONC. 44, 3, p. e628-e636

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  139. Hematopoietic Stem Cell Transplantation with Mesenchymal Stromal Cells in Children with Metachromatic Leukodystrophy

    Cabanillas Stanchi, K. M., Böhringer, J., Strölin, M., Groeschel, S., Lenglinger, K., Treuner, C., Kehrer, C., Laugwitz, L., Bevot, A., Kaiser, N., Schumm, M., Lang, P., Handgretinger, R., Krägeloh-Mann, I., Müller, I. & Döring, M., 04.2022, In: STEM CELLS DEV. 31, 7-8, p. 163-175 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  140. Machine Learning Models Predict the Primary Sites of Head and Neck Squamous Cell Carcinoma Metastases Based on DNA Methylation

    Leitheiser, M., Capper, D., Seegerer, P., Lehmann, A., Schüller, U., Müller, K-R., Klauschen, F., Jurmeister, P. & Michael, B., 04.2022, In: J PATHOL. 256, 4, p. 378-387 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  141. Mucha-Habermann disease: a pediatric case report and proposal of a risk score

    Blohm, M. E., Ebenebe, C. U., Rau, C., Escherich, C., Johannsen, J., Escherich, G., Driemeyer, J., Nagel, P. D., Kobbe, R., Lütgehetmann, M., Lennartz, M., Booken, N., Schneider, S. W. & Singer, D., 04.2022, In: INT J DERMATOL. 61, 4, p. 401-409 9 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  142. Spatial molecular profiling of a central nervous system low-grade diffusely infiltrative tumour with INI1 deficiency featuring a high-grade atypical teratoid/rhabdoid tumour component

    Dottermusch, M., Schumann, Y., Kordes, U., Hasselblatt, M. & Neumann, J. E., 04.2022, In: NEUROPATH APPL NEURO. 48, 3, p. e12777 e12777.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  143. Quantification of Minimal Disease by Digital PCR in ALK-Positive Anaplastic Large Cell Lymphoma: A Step towards Risk Stratification in International Trials?

    Damm-Welk, C., Lovisa, F., Contarini, G., Lüdersen, J., Carraro, E., Knörr, F., Förster, J., Zimmermann, M., Sala, A., Vinti, L., Tondo, A., Pillon, M., Woessmann, W. & Mussolin, L., 27.03.2022, In: CANCERS. 14, 7, 1703.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  144. Remission, treatment failure, and relapse in pediatric ALL: An international consensus of the Ponte-di-Legno Consortium

    Buchmann, S., Schrappe, M., Baruchel, A., Biondi, A., Borowitz, M. J., Campbell, M., Cario, G., Cazzaniga, G., Escherich, G., Harrison, C. J., Heyman, M., Hunger, S. P., Kiss, C., Liu, H-C., Locatelli, F., Loh, M. L., Manabe, A., Mann, G., Pieters, R., Pui, C-H., Rives, S., Schmiegelow, K., Silverman, L. B., Stary, J., Vora, A., Brown, P. A. & Ponte-di-Legno Consortium, 24.03.2022, In: BLOOD. 139, 12, p. 1785-1793 9 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  145. Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors

    Graf, M., Interlandi, M., Moreno, N., Holdhof, D., Göbel, C., Melcher, V., Mertins, J., Albert, T. K., Kastrati, D., Alfert, A., Holsten, T., de Faria, F., Meisterernst, M., Rossig, C., Warmuth-Metz, M., Nowak, J., Meyer Zu Hörste, G., Mayère, C., Nef, S., Johann, P., Frühwald, M. C., Dugas, M., Schüller, U. & Kerl, K., 22.03.2022, In: NAT COMMUN. 13, 1, 1544.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  146. The Reconstitution Dynamics of Cultivated Hematopoietic Stem Cells and Progenitors Is Independent of Age

    Gotzhein, F., Aranyossy, T., Thielecke, L., Sonntag, T., Thaden, V., Fehse, B., Müller, I., Glauche, I. & Cornils, K., 15.03.2022, In: INT J MOL SCI. 23, 6, 3160.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  147. Increased replication stress and R-loop accumulation in EGFRvIII expressing glioblastoma present new therapeutic opportunities

    Struve, N., Hoffer, K., Weik, A-S., Riepen, B., Krug, L., Cetin, M. H., Burmester, J., Ott, L., Liebing, J., Gatzemeier, F., Müller-Goebel, J., Bußmann, L., Parplys, A. C., Unger, K., Mansour, W. Y., Schüller, U., Rieckmann, T., Petersen, C., Rothkamm, K., Short, S. C. & Kriegs, M., 12.03.2022, In: NEURO-ONCOL ADV. 4, 1, p. vdab180 vdab180.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  148. Influence of Fetomaternal Microchimerism on Maternal NK Cell Reactivity against the Child's Leukemic Blasts

    Martin, L-M., Kruchen, A., Fehse, B. & Müller, I., 04.03.2022, In: BIOMEDICINES. 10, 3, 603.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  149. A new amplicon-based gene panel for next generation sequencing characterization of meningiomas

    Mawrin, C., Koch, R., Waldt, N., Sandalcioglu, I. E., Braunsdorf, W. K., Warnke, J-P., Goehre, F., Meisel, H-J., Ewald, C., Neyazi, S., Schüller, U. & Kirches, E., 03.2022, In: BRAIN PATHOL. 32, 2, e13046.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  150. Clinical and molecular characterization of isolated M1 disease in pediatric medulloblastoma: experience from the German HIT-MED studies

    Obrecht, D., Mynarek, M., Hagel, C., Kwiecien, R., Spohn, M., Bockmayr, M., Bison, B., Pfister, S. M., Jones, D. T. W., Sturm, D., von Deimling, A., Sahm, F., von Hoff, K., Juhnke, B-O., Benesch, M., Gerber, N. U., Friedrich, C., von Bueren, A. O., Kortmann, R-D., Schwarz, R., Pietsch, T., Fleischhack, G., Schüller, U. & Rutkowski, S., 03.2022, In: J NEURO-ONCOL. 157, 1, p. 37-48 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  151. Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma

    Hohm, A., Karremann, M., Gielen, G. H., Pietsch, T., Warmuth-Metz, M., Vandergrift, L. A., Bison, B., Stock, A., Hoffmann, M., Pham, M., Kramm, C. M. & Nowak, J., 03.2022, In: CLIN NEURORADIOL. 32, 1, p. 249-258 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  152. Refining M1 stage in medulloblastoma: criteria for cerebrospinal fluid cytology and implications for improved risk stratification from the HIT-2000 trial

    Hagel, C., Sloman, V., Mynarek, M., Petrasch, K., Obrecht, D., Kühl, J., Deinlein, F., Schmid, R., von Bueren, A. O., Friedrich, C., Juhnke, B. O., Gerber, N. U., Kwiecien, R., Girschick, H., Höller, A., Zapf, A., von Hoff, K. & Rutkowski, S., 03.2022, In: EUR J CANCER. 164, p. 30-38

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  153. Types of deviation and review criteria in pretreatment central quality control of tumor bed boost in medulloblastoma-an analysis of the German Radiotherapy Quality Control Panel in the SIOP PNET5 MB trial

    Dietzsch, S., Braesigk, A., Seidel, C., Remmele, J., Kitzing, R., Schlender, T., Mynarek, M., Geismar, D., Jablonska, K., Schwarz, R., Pazos, M., Weber, D. C., Frick, S., Gurtner, K., Matuschek, C., Harrabi, S. B., Glück, A., Lewitzki, V., Dieckmann, K., Benesch, M., Gerber, N. U., Obrecht, D., Rutkowski, S., Timmermann, B. & Kortmann, R-D., 03.2022, In: STRAHLENTHER ONKOL. 198, 3, p. 282-290 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  154. Multimodal Treatment of Nasopharyngeal Carcinoma in Children, Adolescents and Young Adults-Extended Follow-Up of the NPC-2003-GPOH Study Cohort and Patients of the Interim Cohort

    Römer, T., Franzen, S., Kravets, H., Farrag, A., Makowska, A., Christiansen, H., Eble, M. J., Timmermann, B., Staatz, G., Mottaghy, F. M., Bührlen, M., Hagenah, U., Puzik, A., Driever, P. H., Greiner, J., Jorch, N., Tippelt, S., Schneider, D. T., Kropshofer, G., Overbeck, T. R., Christiansen, H., Brozou, T., Escherich, G., Becker, M., Friesenbichler, W., Feuchtinger, T., Puppe, W., Heussen, N., Hilgers, R. D. & Kontny, U., 28.02.2022, In: CANCERS. 14, 5, 1261.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  155. Akute lymphoblastische Leukämie

    Escherich, G., Möricke, A., Horstmann, M. & Schrappe, M., 15.02.2022, Kompendium Internistische Onkologie: Standards in Diagnostik und Therapie. Schmoll, H-J. (ed.). 5 ed. Berlin, Heidelberg: Springer, 11 p.

    Research output: SCORING: Contribution to book/anthologyChapterResearchpeer-review

  156. NET Release of Long-Term Surviving Neutrophils

    Kolman, J. P., Pagerols Raluy, L., Müller, I., Nikolaev, V., Trochimiuk, M., Appl, B., Wadehn, H., Dücker, C., Stoll, F., Boettcher, M., Reinshagen, K. & Trah, J., 15.02.2022, In: FRONT IMMUNOL. 13, p. 815412 815412.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  157. Primary central nervous system sarcoma with DICER1 mutation-treatment results of a novel molecular entity in pediatric Peruvian patients

    Diaz Coronado, R. Y., Mynarek, M., Koelsche, C., Mora Alferez, P., Casavilca Zambrano, S., Wachtel Aptowitzer, A., Sahm, F., von Deimling, A., Schüller, U., Spohn, M., Sturm, D., Pfister, S. M., Morales La Madrid, A., Sernaque Quintana, R., Sarria Bardales, G., Negreiros Chinchihuara, T., Ojeda Medina, L., Garcia-Corrochano Medina, P., Campos Sanchez, D. A., Ponce Farfan, J., Rutkowski, S. & Garcia Leon, J. L., 15.02.2022, In: CANCER-AM CANCER SOC. 128, 4, p. 697-707 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  158. Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma

    Lechner, M., Takahashi, Y., Turri-Zanoni, M., Liu, J., Counsell, N., Hermsen, M., Kaur, R. P., Zhao, T., Ramanathan, M., Schartinger, V. H., Emanuel, O., Helman, S., Varghese, J., Dudas, J., Riechelmann, H., Sprung, S., Haybaeck, J., Howard, D., Engel, N. W., Stewart, S., Brooks, L., Pickles, J. C., Jacques, T. S., Fenton, T. R., Williams, L., Vaz, F. M., O'Flynn, P., Stimpson, P., Wang, S., Hannan, S. A., Unadkat, S., Hughes, J., Dwivedi, R., Forde, C. T., Randhawa, P., Gane, S., Joseph, J., Andrews, P. J., Royle, G., Franchi, A., Maragliano, R., Battocchio, S., Bewicke-Copley, H., Pipinikas, C., Webster, A., Thirlwell, C., Ho, D., Teschendorff, A., Zhu, T., Steele, C. D., Pillay, N., Vanhaesebroeck, B., Mohyeldin, A., Fernandez-Miranda, J., Park, K. W., Le, Q-T., West, R. B., Saade, R., Manes, R. P., Omay, S. B., Vining, E. M., Judson, B. L., Yarbrough, W. G., Sansovini, M., Silvia, N., Grassi, I., Bongiovanni, A., Capper, D., Schüller, U., Thavaraj, S., Sandison, A., Surda, P., Hopkins, C., Ferrari, M., Mattavelli, D., Rampinelli, V., Facchetti, F., Nicolai, P., Bossi, P., Henriquez, O. A., Magliocca, K., Solares, C. A., Wise, S. K., Llorente, J. L., Patel, Z. M., Nayak, J. V., Hwang, P. H., Lacy, P. D., Woods, R., O'Neill, J. P., Jay, A., Carnell, D., Forster, M. D., Ishii, M., London, N. R., Bell, D. M., Gallia, G. L., Castelnuovo, P., Severi, S., Lund, V. J. & Hanna, E. Y., 02.2022, In: EUR J CANCER. 162, p. 221-236 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  159. Final results of the Choroid Plexus Tumor study CPT-SIOP-2000

    Wolff, J. E., Van Gool, S. W., Kutluk, T., Diez, B., Kebudi, R., Timmermann, B., Garami, M., Sterba, J., Fuller, G. N., Bison, B. & Kordes, U. R., 02.2022, In: J NEURO-ONCOL. 156, 3, p. 599-613 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  160. Gain-of-function variant p.Pro2555Arg of von Willebrand factor increases aggregate size through altering stem dynamics

    Huck, V., Chen, P-C., Xu, E-R., Tischer, A., Klemm, U., Aponte-Santamaría, C., Mess, C., Obser, T., Kutzki, F., König, G., Denis, C., Gräter, F., Wilmanns, M., Auton, M., Schneider, S. W., Schneppenheim, R., Hennig, J. & Brehm, M. A., 02.2022, In: THROMB HAEMOSTASIS. 122, 2, p. 226-239 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  161. Hypersensitivity to Pegylated E.colia sparaginase as first-line treatment in contemporary paediatric acute lymphoblastic leukaemia protocols: a meta-analysis of the Ponte di Legno Toxicity working group

    Brigitha, L. J., Fiocco, M., Pieters, R., Albertsen, B. K., Escherich, G., Lopez-Lopez, E., Mondelaers, V., Vora, A., Vrooman, L., Schmiegelow, K., van der Sluis, I. M. & Ponte di Legno toxicity working group, 02.2022, In: EUR J CANCER. 162, p. 65-75 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  162. Maternal versus paternal living kidney transplant donation is associated with lower rejection in young pediatric recipients: A Collaborative Transplant Study report

    Engels, G., Döhler, B., Tönshoff, B., Oh, J., Kruchen, A., Müller, I. & Süsal, C., 02.2022, In: PEDIATR TRANSPLANT. 26, 1, e14154.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  163. Local and Systemic Therapy of Recurrent Medulloblastomas in Children and Adolescents: Results of the P-HIT-REZ 2005 Study

    Gaab, C., Adolph, J. E., Tippelt, S., Mikasch, R., Obrecht, D., Mynarek, M., Rutkowski, S., Pfister, S. M., Milde, T., Witt, O., Bison, B., Warmuth-Metz, M., Kortmann, R-D., Dietzsch, S., Pietsch, T., Timmermann, B., Sträter, R., Bode, U., Faldum, A., Kwiecien, R. & Fleischhack, G., 18.01.2022, In: CANCERS. 14, 3, 471.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  164. Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial

    Bailey, S., André, N., Gandola, L., Massimino, M., Rutkowski, S. & Clifford, S. C., 13.01.2022, In: CANCERS. 14, 2, 374.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  165. Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and high-dose chemotherapy within the prospective P-HIT trial

    Juhnke, B-O., Gessi, M., Gerber, N. U., Friedrich, C., Mynarek, M., von Bueren, A. O., Haberler, C., Schüller, U., Kortmann, R-D., Timmermann, B., Bison, B., Warmuth-Metz, M., Kwiecien, R., Pfister, S. M., Spix, C., Pietsch, T., Kool, M., Rutkowski, S. & von Hoff, K., 05.01.2022, In: NEURO-ONCOLOGY. 24, 1, p. 127-137 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  166. Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

    Das, A., Sudhaman, S., Morgenstern, D., Coblentz, A., Chung, J., Stone, S. C., Alsafwani, N., Liu, Z. A., Karsaneh, O. A. A., Soleimani, S., Ladany, H., Chen, D., Zatzman, M., Cabric, V., Nobre, L., Bianchi, V., Edwards, M., Sambira Nahum, L. C., Ercan, A. B., Nabbi, A., Constantini, S., Dvir, R., Yalon-Oren, M., Campino, G. A., Caspi, S., Larouche, V., Reddy, A., Osborn, M., Mason, G., Lindhorst, S., Bronsema, A., Magimairajan, V., Opocher, E., De Mola, R. L., Sabel, M., Frojd, C., Sumerauer, D., Samuel, D., Cole, K., Chiaravalli, S., Massimino, M., Tomboc, P., Ziegler, D. S., George, B., Van Damme, A., Hijiya, N., Gass, D., McGee, R. B., Mordechai, O., Bowers, D. C., Laetsch, T. W., Lossos, A., Blumenthal, D. T., Sarosiek, T., Yen, L. Y., Knipstein, J., Bendel, A., Hoffman, L. M., Luna-Fineman, S., Zimmermann, S., Scheers, I., Nichols, K. E., Zapotocky, M., Hansford, J. R., Maris, J. M., Dirks, P., Taylor, M. D., Kulkarni, A. V., Shroff, M., Tsang, D. S., Villani, A., Xu, W., Aronson, M., Durno, C., Shlien, A., Malkin, D., Getz, G., Maruvka, Y. E., Ohashi, P. S., Hawkins, C., Pugh, T. J., Bouffet, E. & Tabori, U., 01.2022, In: NAT MED. 28, 1, p. 125-135 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  167. Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD

    Arnold, D. E., Nofal, R., Wakefield, C., Lehmberg, K., Wustrau, K., Albert, M. H., Morris, E. C., Heimall, J. R., Bunin, N. J., Kumar, A., Jordan, M. B., Cole, T., Choo, S., Brettig, T., Speckmann, C., Ehl, S., Salamonowicz, M., Wahlstrom, J., Rao, K., Booth, C., Worth, A. & Marsh, R. A., 01.2022, In: J CLIN IMMUNOL. 42, 1, p. 36-45 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  168. Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity

    Groß, M., Speckmann, C., May, A., Gajardo-Carrasco, T., Wustrau, K., Maier, S. L., Panning, M., Huzly, D., Agaimy, A., Bryceson, Y. T., Choo, S., Chow, C. W., Dückers, G., Fasth, A., Fraitag, S., Gräwe, K., Haxelmans, S., Holzinger, D., Hudowenz, O., Hübschen, J. M., Khurana, C., Kienle, K., Klifa, R., Korn, K., Kutzner, H., Lämmermann, T., Ledig, S., Lipsker, D., Meeths, M., Naumann-Bartsch, N., Rascon, J., Schänzer, A., Seidl, M., Tesi, B., Vauloup-Fellous, C., Vollmer-Kary, B., Warnatz, K., Wehr, C., Neven, B., Vargas, P., Sepulveda, F. E., Lehmberg, K., Schmitt-Graeff, A. & Ehl, S., 01.2022, In: J ALLERGY CLIN IMMUN. 149, 1, p. 388-399.e4

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  169. 2021
  170. Relapsed Medulloblastoma in Pre-Irradiated Patients: Current Practice for Diagnostics and Treatment

    Hill, R. M., Plasschaert, S. L. A., Timmermann, B., Dufour, C., Aquilina, K., Avula, S., Donovan, L., Lequin, M., Pietsch, T., Thomale, U., Tippelt, S., Wesseling, P., Rutkowski, S., Clifford, S. C., Pfister, S. M., Bailey, S. & Fleischhack, G., 28.12.2021, In: CANCERS. 14, 1, 126.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  171. Ex vivo testis explant culture of human testicular tissue

    Aden, N. L., Soave, A., Kordes, U., Bleeke, M., Salzbrunn, A. & von Kopylow, K., 05.12.2021, In: J Reprodmed Endokrinol. 2020, 17 (Supplementum 1), 39-40

    Research output: SCORING: Contribution to journalConference abstract in journalResearch

  172. SIOP PNET5 MB Trial: History and Concept of a Molecularly Stratified Clinical Trial of Risk-Adapted Therapies for Standard-Risk Medulloblastoma

    Mynarek, M., Milde, T., Padovani, L., Janssens, G. O., Kwiecien, R., Mosseri, V., Clifford, S. C., Doz, F. & Rutkowski, S., 02.12.2021, In: CANCERS. 13, 23, 1677.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  173. Dose-adjusted EPOCH-rituximab or intensified B-NHL therapy for pediatric primary mediastinal large B-cell lymphoma

    Knörr, F., Zimmermann, M., Attarbaschi, A., Kabickova, E., Maecker-Kolhoff, B., Ruf, S., Kühnle, I., Ebinger, M., Garthe, A-K., Simonitsch-Klupp, I., Oschlies, I., Klapper, W., Burkhardt, B. & Wößmann, W., 01.12.2021, In: HAEMATOLOGICA. 106, 12, p. 3232-3235 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  174. Clinical evidence for a biological effect of epigenetically active decitabine in relapsed or progressive rhabdoid tumors

    Steinbügl, M., Nemes, K., Johann, P., Kröncke, T., Tüchert, S., da Costa, M. J. G., Ebinger, M., Schüller, U., Sehested, A., Hauser, P., Reinhard, H., Sumerauer, D., Hettmer, S., Jakob, M., Hasselblatt, M., Siebert, R., Witt, O., Gerss, J., Kerl, K. & Frühwald, M. C., 12.2021, In: PEDIATR BLOOD CANCER. 68, 12, e29267.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  175. Double adenomas of the pituitary reveal distinct lineage markers, copy number alterations, and epigenetic profiles

    Hagel, C., Schüller, U., Flitsch, J., Knappe, U. J., Kellner, U., Bergmann, M., Buslei, R., Buchfelder, M., Rüdiger, T., Herms, J. & Saeger, W., 12.2021, In: PITUITARY. 24, 6, p. 904-913 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  176. Co-activation of Sonic hedgehog and Wnt signaling in murine retinal precursor cells drives ocular lesions with features of intraocular medulloepithelioma

    Dottermusch, M., Sumisławski, P., Krevet, J., Middelkamp, M., Voß, H., Siebels, B., Bartsch, H., Sotlar, K., Meyer, P., Frank, S., Korshunov, A., Glatzel, M., Schüller, U. & Neumann, J. E., 16.11.2021, In: ONCOGENESIS. 10, 11, p. 78

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  177. Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles

    Schoennagel, B. P., Müllerleile, K., Tahir, E., Starekova, J., Grosse, R., Yamamura, J., Bannas, P., Adam, G. & Fischer, R., 03.11.2021, In: INSIGHTS IMAGING. 12, 1, 159.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  178. EXTH-70. ESTABLISHMENT OF INTRAVENTRICULAR SHH INHIBITION AS A THERAPEUTIC OPTION IN YOUNG PATIENTS WITH MEDULLOBLASTOMA

    Kresbach, C., Schoof, M., Leven, T., Holst, L., Yorgan, T. A., Wrzeszcz, A., Rutkowski, S. J. & Schüller, U., 11.2021, In: NEURO-ONCOLOGY. 23, Supplement_6, p. vi179

    Research output: SCORING: Contribution to journalConference abstract in journalResearchpeer-review

  179. Hematopoietic stem cell transplantation in children and adolescents with GATA2-related myelodysplastic syndrome

    Bortnick, R., Wlodarski, M., de Haas, V., De Moerloose, B., Dworzak, M., Hasle, H., Masetti, R., Starý, J., Turkiewicz, D., Ussowicz, M., Kozyra, E., Albert, M., Bader, P., Bordon, V., Cario, G., Beier, R., Schulte, J., Bresters, D., Müller, I., Pichler, H., Sedlacek, P., Sauer, M. G., Zecca, M., Göhring, G., Yoshimi, A., Noellke, P., Erlacher, M., Locatelli, F., Niemeyer, C. M. & Strahm, B., 11.2021, In: BONE MARROW TRANSPL. 56, 11, p. 2732-2741 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  180. Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations

    Thalhammer, J., Kindle, G., Nieters, A., Rusch, S., Seppänen, M. R. J., Fischer, A., Grimbacher, B., Edgar, D., Buckland, M., Mahlaoui, N., Ehl, S. & European Society for Immunodeficiencies Registry Working Party, 11.2021, In: J ALLERGY CLIN IMMUN. 148, 5, p. 1332-1341.e5 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  181. Molecular features of non-anaplastic peripheral T-cell lymphoma in children and adolescents

    Au-Yeung, R. K. H., Richter, J., Iaccarino, I., Abramov, D., Bacon, C. M., Balagué, O., d'Amore, E. S. G., Simonitsch-Klupp, I., Hebeda, K., Nakazawa, A., Oschlies, I., Kontny, U., Woessmann, W., Burkhardt, B. & Klapper, W., 11.2021, In: PEDIATR BLOOD CANCER. 68, 11, e29285.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  182. Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas

    Kirches, E., Sahm, F., Korshunov, A., Bluecher, C., Waldt, N., Kropf, S., Schrimpf, D., Sievers, P., Stichel, D., Schüller, U., Schittenhelm, J., Riemenschneider, M. J., Karajannis, M. A., Perry, A., Pietsch, T., Boekhoff, S., Capper, D., Beck, K., Paramasivam, N., Schlesner, M., Brastianos, P. K., Müller, H. L., Pfister, S. M. & Mawrin, C., 11.2021, In: ACTA NEUROPATHOL. 142, 5, p. 873-886 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  183. Recommendations for Diagnosis and Treatment of Children with Transient Abnormal Myelopoiesis (TAM) and Myeloid Leukemia in Down Syndrome (ML-DS)

    Al-Kershi, S., Golnik, R., Flasinski, M., Waack, K., Rasche, M., Creutzig, U., Dworzak, M., Reinhardt, D. & Klusmann, J-H., 11.2021, In: KLIN PADIATR. 233, 6, p. 267-277 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  184. Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

    Sievers, P., Henneken, S. C., Blume, C., Sill, M., Schrimpf, D., Stichel, D., Okonechnikov, K., Reuss, D. E., Benzel, J., Maaß, K. K., Kool, M., Sturm, D., Zheng, T., Ghasemi, D. R., Kohlhof-Meinecke, P., Cruz, O., Suñol, M., Lavarino, C., Ruf, V., Boldt, H. B., Pagès, M., Pouget, C., Schweizer, L., Kranendonk, M. E. G., Akhtar, N., Bunkowski, S., Stadelmann, C., Schüller, U., Mueller, W. C., Dohmen, H., Acker, T., Harter, P. N., Mawrin, C., Beschorner, R., Brandner, S., Snuderl, M., Abdullaev, Z., Aldape, K., Gilbert, M. R., Armstrong, T. S., Ellison, D. W., Capper, D., Ichimura, K., Reifenberger, G., Grundy, R. G., Jabado, N., Krskova, L., Zapotocky, M., Vicha, A., Varlet, P., Wesseling, P., Rutkowski, S., Korshunov, A., Wick, W., Pfister, S. M., Jones, D. T. W., von Deimling, A., Pajtler, K. W. & Sahm, F., 11.2021, In: ACTA NEUROPATHOL. 142, 5, p. 827-839 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  185. Second Paediatric Strategy Forum for anaplastic lymphoma kinase (ALK) inhibition in paediatric malignancies: ACCELERATE in collaboration with the European Medicines Agency with the participation of the Food and Drug Administration

    Pearson, A. D. J., Barry, E., Mossé, Y. P., Ligas, F., Bird, N., de Rojas, T., Zimmerman, Z. F., Wilner, K., Woessmann, W., Weiner, S., Weigel, B., Venkatramani, R., Valteau, D., Trahair, T., Smith, M., Singh, S., Selvaggi, G., Scobie, N., Schleiermacher, G., Richardson, N., Park, J., Nysom, K., Norga, K., Merino, M., McDonough, J., Matloub, Y., Marshall, L. V., Lowe, E., Lesa, G., Irwin, M., Karres, D., Gajjar, A., Doz, F., Fox, E., DuBois, S. G., Donoghue, M., Casanova, M., Caron, H., Buenger, V., Bradford, D., Blanc, P., Barone, A., Reaman, G. & Vassal, G., 11.2021, In: EUR J CANCER. 157, p. 198-213 16 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  186. Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia

    Zielen, S., Duecker, R. P., Woelke, S., Donath, H., Bakhtiar, S., Buecker, A., Kreyenberg, H., Huenecke, S., Bader, P., Mahlaoui, N., Ehl, S., El-Helou, S. M., Pietrucha, B., Plebani, A., van der Flier, M., van Aerde, K., Kilic, S. S., Reda, S. M., Kostyuchenko, L., McDermott, E., Galal, N., Pignata, C., Pérez, J. L. S., Laws, H-J., Niehues, T., Kutukculer, N., Seidel, M. G., Marques, L., Ciznar, P., Edgar, J. D. M., Soler-Palacín, P., von Bernuth, H., Krueger, R., Meyts, I., Baumann, U., Kanariou, M., Grimbacher, B., Hauck, F., Graf, D., Granado, L. I. G., Prader, S., Reisli, I., Slatter, M., Rodríguez-Gallego, C., Arkwright, P. D., Bethune, C., Deripapa, E., Sharapova, S. O., Lehmberg, K., Davies, E. G., Schuetz, C., Kindle, G. & Schubert, R., 11.2021, In: J CLIN IMMUNOL. 41, 8, p. 1878-1892 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  187. Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies

    Adolph, J. E., Fleischhack, G., Gaab, C., Mikasch, R., Mynarek, M., Rutkowski, S., Schüller, U., Pfister, S. M., Pajtler, K. W., Milde, T., Witt, O., Bison, B., Warmuth-Metz, M., Kortmann, R-D., Dietzsch, S., Pietsch, T., Timmermann, B., Tippelt, S. & German GPOH HIT-Network, 11.2021, In: J NEURO-ONCOL. 155, 2, p. 193-202 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  188. The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma

    Bočkaj, I., Martini, T. E. I., de Camargo Magalhães, E. S., Bakker, P. L., Meeuwsen-de Boer, T. G. J., Armandari, I., Meuleman, S. L., Mondria, M. T., Stok, C., Kok, Y. P., Bakker, B., Wardenaar, R., Seiler, J., Broekhuis, M. J. C., van den Bos, H., Spierings, D. C. J., Ringnalda, F. C. A., Clevers, H., Schüller, U., van Vugt, M. A. T. M., Foijer, F. & Bruggeman, S. W. M., 11.2021, In: PLOS GENET. 17, 11, e1009868.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  189. The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets

    van Tilburg, C. M., Pfaff, E., Pajtler, K. W., Langenberg, K. P. S., Fiesel, P., Jones, B. C., Balasubramanian, G. P., Stark, S., Johann, P. D., Blattner-Johnson, M., Schramm, K., Dikow, N., Hirsch, S., Sutter, C., Grund, K., von Stackelberg, A., Kulozik, A. E., Lissat, A., Borkhardt, A., Meisel, R., Reinhardt, D., Klusmann, J-H., Fleischhack, G., Tippelt, S., von Schweinitz, D., Schmid, I., Kramm, C. M., von Bueren, A. O., Calaminus, G., Vorwerk, P., Graf, N., Westermann, F., Fischer, M., Eggert, A., Burkhardt, B., Wößmann, W., Nathrath, M., Hecker-Nolting, S., Frühwald, M. C., Schneider, D. T., Brecht, I. B., Ketteler, P., Fulda, S., Koscielniak, E., Meister, M. T., Scheer, M., Hettmer, S., Schwab, M., Tremmel, R., Øra, I., Hutter, C., Gerber, N. U., Lohi, O., Kazanowska, B., Kattamis, A., Filippidou, M., Goemans, B., Zwaan, C. M., Milde, T., Jäger, N., Wolf, S., Reuss, D., Sahm, F., von Deimling, A., Dirksen, U., Freitag, A., Witt, R., Lichter, P., Kopp-Schneider, A., Jones, D. T. W., Molenaar, J. J., Capper, D., Pfister, S. M. & Witt, O., 11.2021, In: CANCER DISCOV. 11, 11, p. 2764-2779 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  190. Recommendations for Age-Appropriate Testing, Timing, and Frequency of Audiologic Monitoring During Childhood Cancer Treatment: An International Society of Paediatric Oncology Supportive Care Consensus Report

    Meijer, A. J. M., van den Heuvel-Eibrink, M. M., Brooks, B., Am Zehnhoff-Dinnesen, A. G., Knight, K. R., Freyer, D. R., Chang, K. W., Hero, B., Papadakis, V., Frazier, A. L., Blattmann, C., Windsor, R., Morland, B., Bouffet, E., Rutkowski, S., Tytgat, G. A. M., Geller, J. I., Hunter, L. L., Sung, L., Calaminus, G., Carleton, B. C., Helleman, H. W., Foster, J. H., Kruger, M., Cohn, R. J., Landier, W., van Grotel, M., Brock, P. R., Hoetink, A. E., Rajput, K. M. & Society of Paediatric Oncology Supportive Care Committee, 01.10.2021, In: JAMA ONCOL. 7, 10, p. 1550-1558 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  191. Cauda equina paragangliomas express HOXB13

    Bockmayr, M., Körner, M., Schweizer, L. & Schüller, U., 10.2021, In: NEUROPATH APPL NEURO. 47, 6, p. 889-890 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  192. Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes

    Sahoo, S. S., Pastor, V. B., Goodings, C., Voss, R. K., Kozyra, E. J., Szvetnik, A., Noellke, P., Dworzak, M., Starý, J., Locatelli, F., Masetti, R., Schmugge, M., De Moerloose, B., Catala, A., Kállay, K., Turkiewicz, D., Hasle, H., Buechner, J., Jahnukainen, K., Ussowicz, M., Polychronopoulou, S., Smith, O. P., Fabri, O., Barzilai, S., de Haas, V., Baumann, I., Schwarz-Furlan, S., Niewisch, M. R., Sauer, M. G., Burkhardt, B., Lang, P., Bader, P., Beier, R., Müller, I., Albert, M. H., Meisel, R., Schulz, A., Cario, G., Panda, P. K., Wehrle, J., Hirabayashi, S., Derecka, M., Durruthy-Durruthy, R., Göhring, G., Yoshimi-Noellke, A., Ku, M., Lebrecht, D., Erlacher, M., Flotho, C., Strahm, B., Niemeyer, C. M., Wlodarski, M. W. & European Working Group of MDS in Children (EWOG-MDS), 10.2021, In: NAT MED. 27, 10, p. 1806-1817 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  193. Current recommendations for clinical surveillance and genetic testing in rhabdoid tumor predisposition: a report from the SIOPE Host Genome Working Group

    Frühwald, M. C., Nemes, K., Boztug, H., Cornips, M. C. A., Evans, D. G., Farah, R., Glentis, S., Jorgensen, M., Katsibardi, K., Hirsch, S., Jahnukainen, K., Kventsel, I., Kerl, K., Kratz, C. P., Pajtler, K. W., Kordes, U., Ridola, V., Stutz, E. & Bourdeaut, F., 10.2021, In: FAM CANCER. 20, 4, p. 305-316 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  194. Evidence for a low-penetrant extended phenotype of rhabdoid tumor predisposition syndrome type 1 from a kindred with gain of SMARCB1 exon 6

    Kordes, U., Mautner, V-F., Oyen, F., Hagel, C., Hartmann, C., Heuser, M., Frühwald, M., Hasselblatt, M., Oehl-Huber, K., Siebert, R., Schneppenheim, R. & Schüller, U., 10.2021, In: PEDIATR BLOOD CANCER. 68, 10, p. e29185

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  195. Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

    Boer, J. M., Valsecchi, M. G., Hormann, F. M., Antić, Ž., Zaliova, M., Schwab, C., Cazzaniga, G., Arfeuille, C., Cavé, H., Attarbaschi, A., Strehl, S., Escherich, G., Imamura, T., Ohki, K., Grüber, T. A., Sutton, R., Pastorczak, A., Lammens, T., Lambert, F., Li, C. K., Carrillo de Santa Pau, E., Hoffmann, S., Möricke, A., Harrison, C. J., Den Boer, M. L., De Lorenzo, P., Stam, R. W., Bergmann, A. K. & Pieters, R., 10.2021, In: LEUKEMIA. 35, 10, p. 2978-2982 5 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  196. Genetic testing and surveillance in infantile myofibromatosis: a report from the SIOPE Host Genome Working Group

    Hettmer, S., Dachy, G., Seitz, G., Agaimy, A., Duncan, C., Jongmans, M., Hirsch, S., Kventsel, I., Kordes, U., de Krijger, R. R., Metzler, M., Michaeli, O., Nemes, K., Poluha, A., Ripperger, T., Russo, A., Smetsers, S., Sparber-Sauer, M., Stutz, E., Bourdeaut, F., Kratz, C. P. & Demoulin, J-B., 10.2021, In: FAM CANCER. 20, 4, p. 327-336 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  197. Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients

    Hashem, H., Bucciol, G., Ozen, S., Unal, S., Bozkaya, I. O., Akarsu, N., Taskinen, M., Koskenvuo, M., Saarela, J., Dimitrova, D., Hickstein, D. D., Hsu, A. P., Holland, S. M., Krance, R., Sasa, G., Kumar, A. R., Müller, I., Abreu de Sousa, M., Delafontaine, S., Moens, L., Babor, F., Barzaghi, F., Cicalese, M. P., Bredius, R., van Montfrans, J., Baretta, V., Cesaro, S., Stepensky, P., Benedicte, N., Moshous, D., Le Guenno, G., Boutboul, D., Dalal, J., Brooks, J. P., Dokmeci, E., Dara, J., Lucas, C. L., Hambleton, S., Wilson, K., Jolles, S., Koc, Y., Güngör, T., Schnider, C., Candotti, F., Steinmann, S., Schulz, A., Chambers, C., Hershfield, M., Ombrello, A., Kanakry, J. A. & Meyts, I., 10.2021, In: J CLIN IMMUNOL. 41, 7, p. 1633-1647 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  198. Minimal residual disease, long-term outcome, and IKZF1 deletions in children and adolescents with Down syndrome and acute lymphocytic leukaemia: a matched cohort study

    Michels, N., Boer, J. M., Enshaei, A., Sutton, R., Heyman, M., Ebert, S., Fiocco, M., de Groot-Kruseman, H. A., van der Velden, V. H. J., Barbany, G., Escherich, G., Vora, A., Trahair, T., Dalla-Pozza, L., Pieters, R., Zur Stadt, U., Schmiegelow, K., Moorman, A. V., Zwaan, C. M. & den Boer, M. L., 10.2021, In: LANCET HAEMATOL. 8, 10, p. e700-e710

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  199. Primary haemophagocytic lymphohistiocytosis (Chédiak-Higashi Syndrome) triggered by acute SARS-CoV-2 infection in a six-week-old infant

    Lange, M., Linden, T., Müller, H. L., Flasskuehler, M. A., Koester, H., Lehmberg, K., Ledig, S., Ehl, S., Heep, A. & Beske, F., 10.2021, In: BRIT J HAEMATOL. 195, 2, p. 198-200 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  200. Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma

    Liang, H-C., Costanza, M., Prutsch, N., Zimmerman, M. W., Gurnhofer, E., Montes-Mojarro, I. A., Abraham, B. J., Prokoph, N., Stoiber, S., Tangermann, S., Lobello, C., Oppelt, J., Anagnostopoulos, I., Hielscher, T., Pervez, S., Klapper, W., Zammarchi, F., Silva, D-A., Garcia, K. C., Baker, D., Janz, M., Schleussner, N., Fend, F., Pospíšilová, Š., Janiková, A., Wallwitz, J., Stoiber, D., Simonitsch-Klupp, I., Cerroni, L., Pileri, S., de Leval, L., Sibon, D., Fataccioli, V., Gaulard, P., Assaf, C., Knörr, F., Damm-Welk, C., Woessmann, W., Turner, S. D., Look, A. T., Mathas, S., Kenner, L. & Merkel, O., 22.09.2021, In: NAT COMMUN. 12, 1, 5577.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  201. Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma

    DeSisto, J., Lucas Jr, J. T., Xu, K., Donson, A., Lin, T., Sanford, B., Wu, G., Tran, Q. T., Hedges, D., Hsu, C-Y., Armstrong, G. T., Arnold, M., Bhatia, S., Flannery, P., Lemma, R., Hardie, L., Schüller, U., Venkataraman, S., Hoffman, L. M., Dorris, K., Mulcahy Levy, J. M., Hankinson, T. C., Handler, M., Liu, A. K., Foreman, N., Vibhakar, R., Jones, K., Allen, S., Zhang, J., Baker, S. J., Merchant, T. E., Orr, B. A. & Green, A. L., 20.09.2021, In: NAT COMMUN. 12, 1, 5531.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  202. Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src-family kinases as prognostic markers and potential targets

    Bußmann, L., Hoffer, K., von Bargen, C. M., Droste, C., Lange, T., Kemmling, J., Schröder-Schwarz, J., Vu, A. T., Akingunsade, L., Nollau, P., Rangarajan, S., de Wijn, R., Oetting, A., Müller, C., Böckelmann, L. C., Zech, H. B., Berger, J. C., Möckelmann, N., Busch, C-J., Böttcher, A., Gatzemeier, F., Klinghammer, K., Simnica, D., Binder, M., Struve, N., Rieckmann, T., Schumacher, U., Clauditz, T. S., Betz, C. S., Petersen, C., Rothkamm, K., Münscher, A. & Kriegs, M., 01.09.2021, In: INT J CANCER. 149, 5, p. 1166 - 1180 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  203. Atypical Teratoid/Rhabdoid Tumor (AT/RT) With Molecular Features of Pleomorphic Xanthoastrocytoma

    Thomas, C., Federico, A., Sill, M., Bens, S., Oyen, F., Nemes, K., Johann, P. D., Hartmann, C., Hartmann, W., Sumerauer, D., Paterno, V., Samii, A., Kordes, U., Siebert, R., Frühwald, M. C., Paulus, W., Kool, M. & Hasselblatt, M., 01.09.2021, In: AM J SURG PATHOL. 45, 9, p. 1228-1234 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  204. IDH2 R172 Mutations Across Poorly Differentiated Sinonasal Tract Malignancies: Forty Molecularly Homogenous and Histologically Variable Cases With Favorable Outcome

    Glöss, S., Jurmeister, P., Thieme, A., Schmid, S., Cai, W. Y., Serrette, R. N., Perner, S., Ribbat-Idel, J., Pagenstecher, A., Bläker, H., Keber, U., Stadelmann, C., Zechel, S., Johann, P. D., Hasselblatt, M., Paulus, W., Thomas, C., Dohmen, H., Baumhoer, D., Frank, S., Agaimy, A., Schüller, U., Vasudevaraja, V., Snuderl, M., Liu, C. Z., Pfister, D. G., Jungbluth, A. A., Ghossein, R. A., Xu, B., Capper, D. & Dogan, S., 01.09.2021, In: AM J SURG PATHOL. 45, 9, p. 1190-1204 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  205. Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing Surveillance

    Durno, C., Ercan, A. B., Bianchi, V., Edwards, M., Aronson, M., Galati, M., Atenafu, E. G., Abebe-Campino, G., Al-Battashi, A., Alharbi, M., Azad, V. F., Baris, H. N., Basel, D., Bedgood, R., Bendel, A., Ben-Shachar, S., Blumenthal, D. T., Blundell, M., Bornhorst, M., Bronsema, A., Cairney, E., Rhode, S., Caspi, S., Chamdin, A., Chiaravalli, S., Constantini, S., Crooks, B., Das, A., Dvir, R., Farah, R., Foulkes, W. D., Frenkel, Z., Gallinger, B., Gardner, S., Gass, D., Ghalibafian, M., Gilpin, C., Goldberg, Y., Goudie, C., Hamid, S. A., Hampel, H., Hansford, J. R., Harlos, C., Hijiya, N., Hsu, S., Kamihara, J., Kebudi, R., Knipstein, J., Koschmann, C., Kratz, C., Larouche, V., Lassaletta, A., Lindhorst, S., Ling, S. C., Link, M. P., Loret De Mola, R., Luiten, R., Lurye, M., Maciaszek, J. L., MagimairajanIssai, V., Maher, O. M., Massimino, M., McGee, R. B., Mushtaq, N., Mason, G., Newmark, M., Nicholas, G., Nichols, K. E., Nicolaides, T., Opocher, E., Osborn, M., Oshrine, B., Pearlman, R., Pettee, D., Rapp, J., Rashid, M., Reddy, A., Reichman, L., Remke, M., Robbins, G., Roy, S., Sabel, M., Samuel, D., Scheers, I., Schneider, K. W., Sen, S., Stearns, D., Sumerauer, D., Swallow, C., Taylor, L., Thomas, G., Toledano, H., Tomboc, P., Van Damme, A., Winer, I., Yalon, M., Yen, L. Y., Zapotocky, M., Zelcer, S., Ziegler, D. S., Zimmermann, S., Hawkins, C., Malkin, D., Bouffet, E., Villani, A. & Tabori, U., 01.09.2021, In: J CLIN ONCOL. 39, 25, p. 2779-2790 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  206. Therapeutic implications of improved molecular diagnostics for rare CNS-embryonal tumor entities: results of an international, retrospective study

    von Hoff, K., Haberler, C., Schmitt-Hoffner, F., Schepke, E., de Rojas, T., Jacobs, S., Zapotocky, M., Sumerauer, D., Perek-Polnik, M., Dufour, C., van Vuurden, D., Slavc, I., Gojo, J., Pickles, J. C., Gerber, N. U., Massimino, M., Gil-da-Costa, M. J., Garami, M., Kumirova, E., Sehested, A., Scheie, D., Cruz, O., Moreno, L., Cho, J., Zeller, B., Bovenschen, N., Grotzer, M., Alderete, D., Snuderl, M., Zheludkova, O., Golanov, A., Okonechnikov, K., Mynarek, M., Juhnke, B. O., Rutkowski, S., Schüller, U., Pizer, B., Zezschwitz, B. V., Kwiecien, R., Wechsung, M., Konietschke, F., Hwang, E. I., Sturm, D., Pfister, S. M., von Deimling, A., Rushing, E. J., Ryzhova, M., Hauser, P., Łastowska, M., Wesseling, P., Giangaspero, F., Hawkins, C., Figarella-Branger, D., Eberhart, C., Burger, P., Gessi, M., Korshunov, A., Jacques, T. S., Capper, D., Pietsch, T. & Kool, M., 01.09.2021, In: NEURO-ONCOLOGY. 23, 9, p. 1597-1611 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  207. Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion-Positive Supratentorial Ependymomas

    Zheng, T., Ghasemi, D. R., Okonechnikov, K., Korshunov, A., Sill, M., Maass, K. K., Benites Goncalves da Silva, P., Ryzhova, M., Gojo, J., Stichel, D., Arabzade, A., Kupp, R., Benzel, J., Taya, S., Adachi, T., Shiraishi, R., Gerber, N. U., Sturm, D., Ecker, J., Sievers, P., Selt, F., Chapman, R., Haberler, C., Figarella-Branger, D., Reifenberger, G., Fleischhack, G., Rutkowski, S., Donson, A. M., Ramaswamy, V., Capper, D., Ellison, D. W., Herold-Mende, C. C., Schüller, U., Brandner, S., Driever, P. H., Kros, J. M., Snuderl, M., Milde, T., Grundy, R. G., Hoshino, M., Mack, S. C., Gilbertson, R. J., Jones, D. T. W., Kool, M., von Deimling, A., Pfister, S. M., Sahm, F., Kawauchi, D. & Pajtler, K. W., 09.2021, In: CANCER DISCOV. 11, 9, p. 2230-2247 18 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  208. Follow-up evaluation of a web-based pediatric brain tumor board in Latin America

    Rosabal-Obando, M., Osorio, D. S., Lassaletta, A., La Madrid, A. M., Bartels, U., Finlay, J. L., Qaddoumi, I., Rutkowski, S. & Mynarek, M., 09.2021, In: PEDIATR BLOOD CANCER. 68, 9, p. e29073

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  209. Histopathological patterns in atypical teratoid/rhabdoid tumors are related to molecular subgroup.

    Zin, F., Cotter, J. A., Haberler, C., Dottermusch, M., Neumann, J., Schüller, U., Schweizer, L., Thomas, C., Nemes, K., Johann, P-D., Kool, M., Frühwald, M. C., Paulus, W., Judkins, A. R. & Hasselblatt, M., 09.2021, In: BRAIN PATHOL. 31, 5, p. e12967 e12967.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  210. Malignant gliomas with H3F3A G34R mutation or MYCN amplification in pediatric patients with Li Fraumeni syndrome

    Schoof, M., Kordes, U., Volk, A. E., Al-Kershi, S., Kresbach, C. & Schüller, U., 09.2021, In: ACTA NEUROPATHOL. 142, 3, p. 591-593 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  211. SMARCA4-deficient rhabdoid tumours show intermediate molecular features between SMARCB1-deficient rhabdoid tumours and small cell carcinomas of the ovary, hypercalcaemic type

    Andrianteranagna, M., Cyrta, J., Masliah-Planchon, J., Nemes, K., Corsia, A., Leruste, A., Holdhof, D., Kordes, U., Orbach, D., Corradini, N., Entz-Werle, N., Pierron, G., Castex, M-P., Brouchet, A., Weingertner, N., Ranchère, D., Fréneaux, P., Delattre, O., Bush, J., Leary, A., Frühwald, M. C., Schüller, U., Servant, N. & Bourdeaut, F., 09.2021, In: J PATHOL. 255, 1, p. 1-15 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  212. Genotypes of European and Iranian patients with type 3 von Willebrand disease enrolled in 3WINTERS-IPS

    Baronciani, L., Peake, I., Schneppenheim, R., Goodeve, A., Ahmadinejad, M., Badiee, Z., Baghaipour, M-R., Benitez, O., Bodó, I., Budde, U., Cairo, A., Castaman, G., Eshghi, P., Goudemand, J., Hassenpflug, W., Hoorfar, H., Karimi, M., Keikhaei, B., Lassila, R., Leebeek, F. W. G., Lopez Fernandez, M. F., Mannucci, P. M., Marino, R., Nikšić, N., Oyen, F., Santoro, C., Tiede, A., Toogeh, G., Tosetto, A., Trossaert, M., Zetterberg, E. M. K., Eikenboom, J., Federici, A. B. & Peyvandi, F., 10.08.2021, In: BLOOD ADV. 5, 15, p. 2987-3001 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  213. Multi-Scale Input Strategies for Medulloblastoma Tumor Classification using Deep Transfer Learning

    Bengs, M., Pant, S., Bockmayr, M., Schüller, U. & Schlaefer, A., 01.08.2021, In: Current Directions in Biomedical Engineering. 7, 1, 20211115.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  214. Effects of a structured counselling-based intervention to improve physical activity behaviour of adolescents and young adult cancer survivors - the randomized phase II Motivate AYA - MAYA trial

    Salchow, J., Koch, B., Mann, J., von Grundherr, J., Elmers, S., Dwinger, S., Escherich, G., Vettorazzi, E., Reer, R., Sinn, M., Baumann, F., Bokemeyer, C., Stein, A. & Jensen, W., 08.2021, In: CLIN REHABIL. 35, 8, p. 1164-1174 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  215. Inhibition of nuclear export restores nuclear localization and residual tumor suppressor function of truncated SMARCB1/INI1 protein in a molecular subset of atypical teratoid/rhabdoid tumors

    Pathak, R., Zin, F., Thomas, C., Bens, S., Gayden, T., Karamchandani, J., Dudley, R. W., Nemes, K., Johann, P. D., Oyen, F., Kordes, U., Jabado, N., Siebert, R., Paulus, W., Kool, M., Frühwald, M. C., Albrecht, S., Kalpana, G. V. & Hasselblatt, M., 08.2021, In: ACTA NEUROPATHOL. 142, 2, p. 361-374 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  216. Pretreatment central quality control for craniospinal irradiation in non-metastatic medulloblastoma: First experiences of the German radiotherapy quality control panel in the SIOP PNET5 MB trial

    Dietzsch, S., Braesigk, A., Seidel, C., Remmele, J., Kitzing, R., Schlender, T., Mynarek, M., Geismar, D., Jablonska, K., Schwarz, R., Pazos, M., Walser, M., Frick, S., Gurtner, K., Matuschek, C., Harrabi, S. B., Glück, A., Lewitzki, V., Dieckmann, K., Benesch, M., Gerber, N. U., Rutkowski, S., Timmermann, B. & Kortmann, R-D., 08.2021, In: STRAHLENTHER ONKOL. 197, 8, p. 674-682 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  217. Transposable element insertion as a mechanism of SMARCB1 inactivation in atypical teratoid/rhabdoid tumor

    Thomas, C., Oehl-Huber, K., Bens, S., Soschinski, P., Koch, A., Nemes, K., Oyen, F., Kordes, U., Kool, M., Frühwald, M. C., Hasselblatt, M. & Siebert, R., 08.2021, In: GENE CHROMOSOME CANC. 60, 8, p. 586-590 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  218. A "Goldilocks" approach to CNS leukemia is needed

    Halsey, C. & Escherich, G., 29.07.2021, In: BLOOD. 138, 4, p. 288-289 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  219. Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification

    Maire, C. L., Fuh, M. M., Kaulich, K., Fita, K. D., Stevic, I., Heiland, D. H., Welsh, J. A., Jones, J. C., Görgens, A., Ricklefs, T., Dührsen, L., Sauvigny, T., Joosse, S. A., Reifenberger, G., Pantel, K., Glatzel, M., Miklosi, A. G., Felce, J. H., Caselli, M., Pereno, V., Reimer, R., Schlüter, H., Westphal, M., Schüller, U., Lamszus, K. & Ricklefs, F. L., 01.07.2021, In: NEURO-ONCOLOGY. 23, 7, p. 1087-1099 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  220. 68Ga-FAPI-PET/CT improves diagnostic staging and radiotherapy planning of adenoid cystic carcinomas – Imaging analysis and histological validation

    Röhrich, M., Syed, M., Liew, D. P., Giesel, F. L., Liermann, J., Choyke, P. L., Wefers, A. K., Ritz, T., Szymbara, M., Schillings, L., Heger, U., Rathke, H., Kratochwil, C., Huber, P. E., Deimling, A. V., Debus, J., Kauczor, H-U., Haberkorn, U. & Adeberg, S., 07.2021, In: RADIOTHER ONCOL. 160, p. 192-201 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  221. Feasibility of Proton Beam Therapy for Infants with Brain Tumours: Experiences from the Prospective KiProReg Registry Study

    Jazmati, D., Steinmeier, T., Ahamd Khalil, D., Frisch, S., Peters, S., Schulze Schleithoff, S., Bäumer, C., Rutkowski, S., Frühwald, M. C., Blase, C., Tippelt, S. & Timmermann, B., 07.2021, In: CLIN ONCOL-UK. 33, 7, p. e295-e304

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  222. HSCT is effective in patients with PSTPIP1-associated myeloid-related proteinemia inflammatory (PAMI) syndrome

    Laberko, A., Burlakov, V., Maier, S., Abinun, M., Skinner, R., Kozlova, A., Suri, D., Lehmberg, K., Müller, I., Balashov, D., Novichkova, G., Holzinger, D., Gennery, A. R. & Shcherbina, A., 07.2021, In: J ALLERGY CLIN IMMUN. 148, 1, p. 250-255.e1

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  223. Multicentric dermatofibrosarcoma protuberans in a child with severe combined immunodeficiency due to adenosine deaminase deficiency

    Wahjudi, T. D., Kutzner, H., Bleeke, M. & Hoeger, P. H., 07.2021, In: PEDIATR DERMATOL. 38, 4, p. 875-878 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  224. Severe toxicity free survival: physician-derived definitions of unacceptable long-term toxicities following acute lymphocytic leukaemia

    Andrés-Jensen, L., Attarbaschi, A., Bardi, E., Barzilai-Birenboim, S., Bhojwani, D., Hagleitner, M. M., Halsey, C., Harila-Saari, A., van Litsenburg, R. R. L., Hudson, M. M., Jeha, S., Kato, M., Kremer, L., Mlynarski, W., Möricke, A., Pieters, R., Piette, C., Raetz, E., Ronceray, L., Toro, C., Grazia Valsecchi, M., Vrooman, L. M., Weinreb, S., Winick, N., Schmiegelow, K. & Ponte di Legno Severe Toxicity Working Group, 07.2021, In: LANCET HAEMATOL. 8, 7, p. e513-e523 11 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  225. Genetic and Clinical Predictors of Left Atrial Thrombus: A Single Center Case-Control Study

    Springer, A., Schleberger, R., Oyen, F., Hoffmann, B. A., Willems, S., Meyer, C., Langer, F., Schnabel, R. B., Kirchhof, P., Schneppenheim, R. & Lemoine, M. D., 30.06.2021, In: CLIN APPL THROMB-HEM. 27, p. 10760296211021171

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  226. Local and Systemic Therapy of Recurrent Ependymoma in Children and Adolescents: Short- and Long-term Results of the E-HIT-REZ 2005 Study

    Adolph, J. E., Fleischhack, G., Mikasch, R., Zeller, J., Warmuth-Metz, M., Bison, B., Mynarek, M., Rutkowski, S., Schüller, U., von Hoff, K., Obrecht, D., Pietsch, T., Pfister, S. M., Pajtler, K. W., Witt, O., Witt, H., Kortmann, R-D., Timmermann, B., Krauß, J., Frühwald, M. C., Faldum, A., Kwiecien, R., Bode, U., Tippelt, S. & German GPOH HIT-Network, 01.06.2021, In: NEURO-ONCOLOGY. 23, 6, p. 1012-1023 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  227. Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target

    Larose, H., Prokoph, N., Matthews, J. D., Schlederer, M., Högler, S., Alsulami, A. F., Ducray, S. P., Nuglozeh, E., Fazaludeen, F. M. S., Elmouna, A., Ceccon, M., Mologni, L., Gambacorti-Passerini, C., Hoefler, G., Lobello, C., Pospisilova, S., Janikova, A., Woessmann, W., Damm-Welk, C., Zimmermann, M., Federova, A., Malone, A., Smith, O., Wasik, M., Inghirami, G., Lamant, L., Blundell, T. L., Klapper, W., Merkel, O., Burke, G. A. A., Mian, S., Ashankyty, I., Kenner, L. & Turner, S. D., 01.06.2021, In: HAEMATOLOGICA. 106, 6, p. 1693-1704 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  228. Irradiation-free re-conditioning in children following graft failure of a T cell-depleted graft from a haploidentical parent

    Aydin, S., Kruchen, A., Wustrau, K., Doering, M., Schrum, J. & Müller, I., 06.2021, In: BONE MARROW TRANSPL. 56, 6, p. 1452-1454 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  229. Neurofibromatosis type 2 predisposes to ependymomas of various localization, histology, and molecular subtype

    Kresbach, C., Dorostkar, M. M., Suwala, A. K., Wefers, A. K., Schweizer, L., Engertsberger, L., Bison, B., Mynarek, M., Kloth-Stachnau, K., Spohn, M., von Deimling, A., Benesch, M., Hagel, C., Mautner, V-F., Rutkowski, S. & Schüller, U., 06.2021, In: ACTA NEUROPATHOL. 141, 6, p. 971-974 4 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  230. Simultaneous Brg1 Knockout and MYCN Overexpression in Cerebellar Granule Neuron Precursors Is Insufficient to Drive Tumor Formation but Temporarily Enhances their Proliferation and Delays their Migration

    Holdhof, D., On, J. H., Schoof, M., Göbel, C. & Schüller, U., 06.2021, In: CEREBELLUM. 20, 3, p. 410-419 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  231. TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma

    Thomas, C., Thierfelder, F., Träger, M., Soschinski, P., Müther, M., Edelmann, D., Förster, A., Geiler, C., Kim, H-Y., Filipski, K., Harter, P. N., Schittenhelm, J., Eckert, F., Ntoulias, G., May, S-A., Stummer, W., Onken, J., Vajkoczy, P., Schüller, U., Heppner, F. L., Capper, D., Koch, A., Kaul, D., Paulus, W., Hasselblatt, M. & Schweizer, L., 06.2021, In: ACTA NEUROPATHOL. 141, 6, p. 959-970 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  232. Brahma-related gene 1 has time-specific roles during brain and eye development

    Holdhof, D., Schoof, M., Neyazi, S., Spohn, M., Kresbach, C., Göbel, C., Hellwig, M., Indenbirken, D., Moreno, N., Kerl, K. & Schüller, U., 21.05.2021, In: DEVELOPMENT. 148, 10, dev196147.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  233. Second malignancies after treatment of childhood non-Hodgkin lymphoma: a report of the Berlin-Frankfurt-Muenster study group

    Moser, O., Zimmermann, M., Meyer, U., Klapper, W., Oschlies, I., Schrappe, M., Attarbaschi, A., Mann, G., Niggli, F., Spix, C., Kontny, U., Klingebiel, T., Reiter, A., Burkhardt, B. & Woessmann, W., 01.05.2021, In: HAEMATOLOGICA. 106, 5, p. 1390-1400 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  234. Clinical and genetic characteristics of children with acute lymphoblastic leukemia and Li-Fraumeni syndrome

    Winter, G., Kirschner-Schwabe, R., Groeneveld-Krentz, S., Escherich, G., Möricke, A., von Stackelberg, A., Stanulla, M., Bailey, S., Richter, L., Steinemann, D., Ripperger, T., Escudero, A., Farah, R., Lohi, O., Wadt, K., Jongmans, M., van Engelen, N., Eckert, C. & Kratz, C. P., 05.2021, In: LEUKEMIA. 35, 5, p. 1475-1479 5 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  235. Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study

    Liu, A. P. Y., Li, B. K., Pfaff, E., Gudenas, B., Vasiljevic, A., Orr, B. A., Dufour, C., Snuderl, M., Karajannis, M. A., Rosenblum, M. K., Hwang, E. I., Ng, H-K., Hansford, J. R., Szathmari, A., Faure-Conter, C., Merchant, T. E., Levine, M., Bouvier, N., von Hoff, K., Mynarek, M., Rutkowski, S., Sahm, F., Kool, M., Hawkins, C., Onar-Thomas, A., Robinson, G. W., Gajjar, A., Pfister, S. M., Bouffet, E., Northcott, P. A., Jones, D. T. W. & Huang, A., 05.2021, In: ACTA NEUROPATHOL. 141, 5, p. 771-785 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  236. DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells

    Chung, J., Maruvka, Y. E., Sudhaman, S., Kelly, J., Haradhvala, N. J., Bianchi, V., Edwards, M., Forster, V. J., Nunes, N. M., Galati, M. A., Komosa, M., Deshmukh, S., Cabric, V., Davidson, S., Zatzman, M., Light, N., Hayes, R., Brunga, L., Anderson, N. D., Ho, B., Hodel, K. P., Siddaway, R., Morrissy, A. S., Bowers, D. C., Larouche, V., Bronsema, A., Osborn, M., Cole, K. A., Opocher, E., Mason, G., Thomas, G. A., George, B., Ziegler, D. S., Lindhorst, S., Vanan, M., Yalon-Oren, M., Reddy, A. T., Massimino, M., Tomboc, P., Van Damme, A., Lossos, A., Durno, C., Aronson, M., Morgenstern, D. A., Bouffet, E., Huang, A., Taylor, M. D., Villani, A., Malkin, D., Hawkins, C. E., Pursell, Z. F., Shlien, A., Kunkel, T. A., Getz, G. & Tabori, U., 05.2021, In: CANCER DISCOV. 11, 5, p. 1176-1191 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  237. Integrative genomic analysis of pediatric T- cell lymphoblastic lymphoma reveals candidates of clinical significance

    Khanam, T., Sandmann, S., Seggewiss, J., Ruether, C. M., Zimmermann, M., Norvil, A. B., Bartenhagen, C., Randau, G., Mueller, S., Herbrüggen, H., Hoffmann, P., Herms, S., Wei, L., Wöste, M., Wünsch, C., Gowher, H., Oschlies, I., Klapper, W., Woessmann, W., Dugas, M. & Burkhardt, B., 29.04.2021, In: BLOOD. 137, 17, p. 2347-2359 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  238. Treatment and Outcome Analysis of 639 Relapsed Non-Hodgkin Lymphomas in Children and Adolescents and Resulting Treatment Recommendations

    Burkhardt, B., Taj, M., Garnier, N., Minard-Colin, V., Hazar, V., Mellgren, K., Osumi, T., Fedorova, A., Myakova, N., Verdu-Amoros, J., Andres, M., Kabickova, E., Attarbaschi, A., Chiang, A. K. S., Bubanska, E., Donska, S., Hjalgrim, L. L., Wachowiak, J., Pieczonka, A., Uyttebroeck, A., Lazic, J., Loeffen, J., Buechner, J., Niggli, F., Csoka, M., Krivan, G., Palma, J., Burke, G. A. A., Beishuizen, A., Koeppen, K., Mueller, S., Herbrueggen, H., Woessmann, W., Zimmermann, M., Balduzzi, A. & Pillon, M., 25.04.2021, In: CANCERS. 13, 9, 2075.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  239. Minimal Disease Monitoring in Pediatric Non-Hodgkin's Lymphoma: Current Clinical Application and Future Challenges

    Mussolin, L., Damm-Welk, C., Pillon, M. & Woessmann, W., 15.04.2021, In: CANCERS. 13, 8, 1907.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  240. An extracellular vesicle-related gene expression signature identifies high-risk patients in medulloblastoma

    Albert, T. K., Interlandi, M., Sill, M., Graf, M., Moreno, N., Menck, K., Rohlmann, A., Melcher, V., Korbanka, S., Meyer Zu Hörste, G., Lautwein, T., Frühwald, M. C., Krebs, C. F., Holdhof, D., Schoof, M., Bleckmann, A., Missler, M., Dugas, M., Schüller, U., Jäger, N., Pfister, S. M. & Kerl, K., 12.04.2021, In: NEURO-ONCOLOGY. 23, 4, p. 586-598 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  241. The genetic landscape of choroid plexus tumors in children and adults

    Thomas, C., Soschinski, P., Zwaig, M., Oikonomopoulos, S., Okonechnikov, K., Pajtler, K. W., Sill, M., Schweizer, L., Koch, A., Neumann, J., Schüller, U., Sahm, F., Rauschenbach, L., Keyvani, K., Proescholdt, M., Riemenschneider, M. J., Segewiß, J., Ruckert, C., Grauer, O., Monoranu, C-M., Lamszus, K., Patrizi, A., Kordes, U., Siebert, R., Kool, M., Ragoussis, J., Foulkes, W. D., Paulus, W., Rivera, B. & Hasselblatt, M., 12.04.2021, In: NEURO-ONCOLOGY. 23, 4, p. 650-660 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  242. SSBP2-CSF1R is a recurrent fusion in B-lineage acute lymphoblastic leukemia with diverse genetic presentation and variable outcome

    Schwab, C. J., Roberts, K. G., Boer, J. M., Gohring, G., Steinemann, D., Vora, A., Macartney, C., Hough, R. E., Thorn, Z., Dillon, R., Escherich, G., Cazzaniga, G., Schlegelberger, B., Loh, M. L., Den Boer, M. L., Moorman, A. V. & Harrison, C. J., 01.04.2021, In: BLOOD. 137, 13, p. 1835-1838 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  243. Accurate calling of KIAA1549-BRAF fusions from DNA of human brain tumours using methylation array-based copy number and gene panel sequencing data

    Stichel, D., Schrimpf, D., Sievers, P., Reinhardt, A., Suwala, A. K., Sill, M., Reuss, D. E., Korshunov, A., Casalini, B. M., Sommerkamp, A. C., Ecker, J., Selt, F., Sturm, D., Gnekow, A., Koch, A., Simon, M., Hernáiz Driever, P., Schüller, U., Capper, D., van Tilburg, C. M., Witt, O., Milde, T., Pfister, S. M., Jones, D. T. W., von Deimling, A., Sahm, F. & Wefers, A. K., 04.2021, In: NEUROPATH APPL NEURO. 47, 3, p. 406-414 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  244. Auswirkungen der COVID-19 Pandemie auf die medizinische Versorgung von Patienten mit angeborenen Blutungsneigungen

    Olivieri, M., Halimeh, S., Wermes, C., Hassenpflug, W., Holstein, K. & von Mackensen, S., 04.2021, In: GESUNDHEITSWESEN. 83, 4, p. 282-290 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  245. Correction to: Mutations within FGFR1 are associated with superior outcome in a series of 83 diffuse midline gliomas with H3F3A K27M mutations

    Schüller, U., Iglauer, P., Dorostkar, M. M., Mawrin, C., Herms, J., Giese, A., Glatzel, M. & Neumann, J. E., 04.2021, In: ACTA NEUROPATHOL. 141, 4, p. 627

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  246. Morphological and molecular breast cancer profiling through explainable machine learning

    Binder, A., Bockmayr, M., Hägele, M., Wienert, S., Heim, D., Hellweg, K., Ishii, M., Stenzinger, A., Hocke, A., Denkert, C., Müller, K. R. & Klauschen, F., 04.2021, In: NAT MACH INTELL. 3, 4, p. 355-366 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  247. SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2

    von Wenserski, L., Schultheiß, C., Bolz, S., Schliffke, S., Simnica, D., Willscher, E., Gerull, H., Wolters-Eisfeld, G., Riecken, K., Fehse, B., Altfeld, M., Nollau, P. & Binder, M., 04.2021, In: LEUKEMIA. 35, 4, p. 1073-1086 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  248. The transcriptional landscape of Shh medulloblastoma

    Skowron, P., Farooq, H., Cavalli, F. M. G., Morrissy, A. S., Ly, M., Hendrikse, L. D., Wang, E. Y., Djambazian, H., Zhu, H., Mungall, K. L., Trinh, Q. M., Zheng, T., Dai, S., Stucklin, A. S. G., Vladoiu, M. C., Fong, V., Holgado, B. L., Nor, C., Wu, X., Abd-Rabbo, D., Bérubé, P., Wang, Y. C., Luu, B., Suarez, R. A., Rastan, A., Gillmor, A. H., Lee, J. J. Y., Zhang, X. Y., Daniels, C., Dirks, P., Malkin, D., Bouffet, E., Tabori, U., Loukides, J., Doz, F. P., Bourdeaut, F., Delattre, O. O., Masliah-Planchon, J., Ayrault, O., Kim, S-K., Meyronet, D., Grajkowska, W. A., Carlotti, C. G., de Torres, C., Mora, J., Eberhart, C. G., Van Meir, E. G., Kumabe, T., French, P. J., Kros, J. M., Jabado, N., Lach, B., Pollack, I. F., Hamilton, R. L., Rao, A. A. N., Giannini, C., Olson, J. M., Bognár, L., Klekner, A., Zitterbart, K., Phillips, J. J., Thompson, R. C., Cooper, M. K., Rubin, J. B., Liau, L. M., Garami, M., Hauser, P., Li, K. K. W., Ng, H-K., Poon, W. S., Yancey Gillespie, G., Chan, J. A., Jung, S., McLendon, R. E., Thompson, E. M., Zagzag, D., Vibhakar, R., Ra, Y. S., Garre, M. L., Schüller, U., Shofuda, T., Faria, C. C., López-Aguilar, E., Zadeh, G., Hui, C-C., Ramaswamy, V., Bailey, S. D., Jones, S. J., Mungall, A. J., Moore, R. A., Calarco, J. A., Stein, L. D., Bader, G. D., Reimand, J., Ragoussis, J., Weiss, W. A., Marra, M. A., Suzuki, H. & Taylor, M. D., 19.03.2021, In: NAT COMMUN. 12, 1, p. 1749

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  249. Genome-wide interference of ZNF423 with B-lineage transcriptional circuitries in acute lymphoblastic leukemia

    Iglesias, P., Puller, A-C., Seoane, M., Spohn, M., Raasch, S., Klokow, M., Müller, J., Burkhardt, L., Indenbirken, D. & Horstmann, M. A., 09.03.2021, In: BLOOD ADV. 5, 5, p. 1209-1223 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  250. Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma

    Kumar, R., Smith, K. S., Deng, M., Terhune, C., Robinson, G. W., Orr, B. A., Liu, A. P. Y., Lin, T., Billups, C. A., Chintagumpala, M., Bowers, D. C., Hassall, T. E., Hansford, J. R., Khuong-Quang, D. A., Crawford, J. R., Bendel, A. E., Gururangan, S., Schroeder, K., Bouffet, E., Bartels, U., Fisher, M. J., Cohn, R., Partap, S., Kellie, S. J., McCowage, G., Paulino, A. C., Rutkowski, S., Fleischhack, G., Dhall, G., Klesse, L. J., Leary, S., Nazarian, J., Kool, M., Wesseling, P., Ryzhova, M., Zheludkova, O., Golanov, A. V., McLendon, R. E., Packer, R. J., Dunham, C., Hukin, J., Fouladi, M., Faria, C. C., Pimentel, J., Walter, A. W., Jabado, N., Cho, Y-J., Perreault, S., Croul, S. E., Zapotocky, M., Hawkins, C., Tabori, U., Taylor, M. D., Pfister, S. M., Klimo, P., Boop, F. A., Ellison, D. W., Merchant, T. E., Onar-Thomas, A., Korshunov, A., Jones, D. T. W., Gajjar, A., Ramaswamy, V. & Northcott, P. A., 01.03.2021, In: J CLIN ONCOL. 39, 7, p. 807-821 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  251. Is hematopoietic stem cell transplantation a therapeutic option for mucolipidosis type II?

    Ammer, L. S., Pohl, S., Breyer, S. R., Aries, C., Denecke, J., Perez, A., Petzoldt, M., Schrum, J., Müller, I. & Muschol, N. M., 03.2021, In: MOL GENET METAB REP. 26, 100704.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  252. Is neutralization of IFN-γ sufficient to control inflammation in HLH?

    Ehl, S., von Bahr Greenwood, T., Bergsten, E., Fischer, A., Henter, J-I., Hines, M., Lehmberg, K., Janka, G., Moshous, D. & Nichols, K. E., 03.2021, In: PEDIATR BLOOD CANCER. 68, 3, p. e28886

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  253. Long-term follow-up after the application of mesenchymal stromal cells in children and adolescents with steroid-refractory graft-versus-host disease

    Döring, M., Cabanillas Stanchi, K. M., Lenglinger, K., Treuner, C., Gieseke, F., Erbacher, A., Mezger, M., Vaegler, M., Schlegel, P-G., Greil, J., Bettoni da Cunha Riehm, C., Faul, C., Schumm, M., Lang, P., Handgretinger, R. & Müller, I., 03.2021, In: STEM CELLS DEV. 30, 5, p. 234-246 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  254. Neuro-meningeal relapse in anaplastic large-cell lymphoma: incidence, risk factors and prognosis - a report from the European intergroup for childhood non-Hodgkin lymphoma

    Del Baldo, G., Abbas, R., Woessmann, W., Horibe, K., Pillon, M., Burke, A., Beishuizen, A., Rigaud, C., Le Deley, M-C., Lamant, L. & Brugières, L., 03.2021, In: BRIT J HAEMATOL. 192, 6, p. 1039-1048 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  255. Supratentorial ependymoma in childhood: more than just RELA or YAP

    Zschernack, V., Jünger, S. T., Mynarek, M., Rutkowski, S., Garre, M. L., Ebinger, M., Neu, M., Faber, J., Erdlenbruch, B., Claviez, A., Bielack, S., Brozou, T., Frühwald, M. C., Dörner, E., Dreschmann, V., Stock, A., Solymosi, L., Hench, J., Frank, S., Vokuhl, C., Waha, A., Andreiuolo, F. & Pietsch, T., 03.2021, In: ACTA NEUROPATHOL. 141, 3, p. 455-466 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  256. Atypical teratoid/rhabdoid tumors (ATRTs) with SMARCA4 mutation are molecularly distinct from SMARCB1-deficient cases

    Holdhof, D., Johann, P. D., Spohn, M., Bockmayr, M., Safaei, S., Joshi, P., Masliah-Planchon, J., Ho, B., Andrianteranagna, M., Bourdeaut, F., Huang, A., Kool, M., Upadhyaya, S. A., Bendel, A. E., Indenbirken, D., Foulkes, W. D., Bush, J. W., Creytens, D., Kordes, U., Frühwald, M. C., Hasselblatt, M. & Schüller, U., 02.2021, In: ACTA NEUROPATHOL. 141, 2, p. 291-301 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  257. Evidence for a low-penetrant extended phenotype of RTPS1 from a kindred with gain of SMARCB1 exon 6

    Kordes, U., Mautner, V., Oyen, F., Hagel, C., Hartmann, C., Heuser, M., Frühwald, M., Hasselblatt, M., Oehl-Huber, K., Siebert, R., Schneppenheim, R. & Schüller, U., 02.2021

    Research output: Other contributionOtherResearch

  258. Mutations within FGFR1 are associated with superior outcome in a series of 83 diffuse midline gliomas with H3F3A K27M mutations

    Schüller, U., Iglauer, P., Dorostkar, M. M., Mawrin, C., Herms, J., Giese, A., Glatzel, M. & Neumann, J. E., 02.2021, In: ACTA NEUROPATHOL. 141, 2, p. 323-325 3 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  259. Reconstructing clonal evolution in relapsed and non-relapsed Burkitt lymphoma

    Reutter, K., Sandmann, S., Rohde, J., Müller, S., Wöste, M., Khanam, T., Michgehl, U., Klapper, W., Wößmann, W., Seggewiß, J., Lenz, G., Dugas, M. & Burkhardt, B., 02.2021, In: LEUKEMIA. 35, 2, p. 639-643 5 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  260. Second malignant neoplasms after treatment of non-Hodgkin's lymphoma-a retrospective multinational study of 189 children and adolescents

    Attarbaschi, A., Carraro, E., Ronceray, L., Andrés, M., Barzilai-Birenboim, S., Bomken, S., Brugières, L., Burkhardt, B., Ceppi, F., Chiang, A. K. S., Csoka, M., Fedorova, A., Jazbec, J., Kabickova, E., Loeffen, J., Mellgren, K., Miakova, N., Moser, O., Osumi, T., Pourtsidis, A., Rigaud, C., Uyttebroeck, A., Woessmann, W., Pillon, M. & European Intergroup for Childhood Non-Hodgkin’s Lymphoma (EICNHL) and the International Berlin-Frankfurt-Münster (i-BFM) Study Group, 02.2021, In: LEUKEMIA. 35, 2, p. 534-549 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  261. Sarcoma classification by DNA methylation profiling

    Koelsche, C., Schrimpf, D., Stichel, D., Sill, M., Sahm, F., Reuss, D. E., Blattner, M., Worst, B., Heilig, C. E., Beck, K., Horak, P., Kreutzfeldt, S., Paff, E., Stark, S., Johann, P., Selt, F., Ecker, J., Sturm, D., Pajtler, K. W., Reinhardt, A., Wefers, A. K., Sievers, P., Ebrahimi, A., Suwala, A., Fernández-Klett, F., Casalini, B., Korshunov, A., Hovestadt, V., Kommoss, F. K. F., Kriegsmann, M., Schick, M., Bewerunge-Hudler, M., Milde, T., Witt, O., Kulozik, A. E., Kool, M., Romero-Pérez, L., Grünewald, T. G. P., Kirchner, T., Wick, W., Platten, M., Unterberg, A., Uhl, M., Abdollahi, A., Debus, J., Lehner, B., Thomas, C., Hasselblatt, M., Paulus, W., Hartmann, C., Staszewski, O., Prinz, M., Hench, J., Frank, S., Versleijen-Jonkers, Y. M. H., Weidema, M. E., Mentzel, T., Griewank, K., de Álava, E., Martín, J. D., Gastearena, M. A. I., Chang, K. T-E., Low, S. Y. Y., Cuevas-Bourdier, A., Mittelbronn, M., Mynarek, M., Rutkowski, S., Schüller, U., Mautner, V. F., Schittenhelm, J., Serrano, J., Snuderl, M., Büttner, R., Klingebiel, T., Buslei, R., Gessler, M., Wesseling, P., Dinjens, W. N. M., Brandner, S., Jaunmuktane, Z., Lyskjær, I., Schirmacher, P., Stenzinger, A., Brors, B., Glimm, H., Heining, C., Tirado, O. M., Sáinz-Jaspeado, M., Mora, J., Alonso, J., Del Muro, X. G., Moran, S., Esteller, M., Benhamida, J. K., Ladanyi, M., Wardelmann, E., Antonescu, C., Flanagan, A., Dirksen, U., Hohenberger, P., Baumhoer, D., Hartmann, W., Vokuhl, C., Flucke, U., Petersen, I., Mechtersheimer, G., Capper, D., Jones, D. T. W., Fröhling, S., Pfister, S. M. & von Deimling, A., 21.01.2021, In: NAT COMMUN. 12, 1, p. 498

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  262. Detailed Clinical and Histopathological Description of 8 Cases of Molecularly Defined CNS Neuroblastomas

    Holsten, T., Lubieniecki, F., Spohn, M., Mynarek, M., Bison, B., Löbel, U., Rutkowski, S. & Schüller, U., 01.01.2021, In: J NEUROPATH EXP NEUR. 80, 1, p. 52-59 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  263. Clinical and genetic risk factors define two risk groups of extracranial malignant rhabdoid tumours (eMRT/RTK)

    Nemes, K., Bens, S., Kachanov, D., Teleshova, M., Hauser, P., Simon, T., Tippelt, S., Woessmann, W., Beck, O., Flotho, C., Grigull, L., Driever, P. H., Schlegel, P-G., Khurana, C., Hering, K., Kolb, R., Leipold, A., Abbink, F., Gil-Da-Costa, M. J., Benesch, M., Kerl, K., Lowis, S., Marques, C. H., Graf, N., Nysom, K., Vokuhl, C., Melchior, P., Kröncke, T., Schneppenheim, R., Kordes, U., Gerss, J., Siebert, R., Furtwängler, R. & Frühwald, M. C., 01.2021, In: EUR J CANCER. 142, p. 112-122 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  264. Ependymoma relapse goes along with a relatively stable epigenome, but a severely altered tumor morphology

    Yang, D., Holsten, T., Börnigen, D., Frank, S., Mawrin, C., Glatzel, M. & Schüller, U., 01.2021, In: BRAIN PATHOL. 31, 1, p. 33-44 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  265. Outcomes of paediatric patients with B-cell acute lymphocytic leukaemia with ABL-class fusion in the pre-tyrosine-kinase inhibitor era. a multicentre, retrospective, cohort study

    den Boer, M. L., Cario, G., Moorman, A. V., Boer, J. M., de Groot-Kruseman, H. A., Fiocco, M., Escherich, G., Imamura, T., Yeoh, A., Sutton, R., Dalla-Pozza, L., Kiyokawa, N., Schrappe, M., Roberts, K. G., Mullighan, C. G., Hunger, S. P., Vora, A., Attarbaschi, A., Zaliova, M., Elitzur, S., Cazzaniga, G., Biondi, A., Loh, M. L., Pieters, R. & Ponte di Legno Childhood ALL Working Group, 01.2021, In: LANCET HAEMATOL. 8, 1, p. e55-e66

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  266. Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant

    Mika, T., Vangala, D., Eckhardt, M., La Rosée, P., Lange, C., Lehmberg, K., Wohlschläger, C., Biskup, S., Fuchs, I., Mann, J., Ehl, S., Warnatz, K. & Schroers, R., 2021, In: FRONT IMMUNOL. 12, 682934.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  267. Defining the Spectrum, Treatment and Outcome of Patients With Genetically Confirmed Gorlin Syndrome From the HIT-MED Cohort

    Kloth, K., Obrecht, D., Sturm, D., Pietsch, T., Warmuth-Metz, M., Bison, B., Mynarek, M. & Rutkowski, S., 2021, In: FRONT ONCOL. 11, 756025.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  268. Diagnostics and Diagnosis of Late Effects in Childhood Brain Tumour Survivors

    Tallen, G., Mynarek, M., Tischler, T., Weller, M. & Rutkowski, S. J., 2021, Late Treatment Effects and Cancer Survivor Care in the Young: From Childhood to Early Adulthood. Beck, J. D., Bokemeyer, C. & Langer, T. (eds.). 1 ed. Cham: Springer Nature Switzerland, p. 239-251 13 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesEducationpeer-review

  269. DIMEimmune: Robust estimation of infiltrating lymphocytes in CNS tumors from DNA methylation profiles

    Safaei, S., Mohme, M., Niesen, J., Schüller, U. & Bockmayr, M., 2021, In: ONCOIMMUNOLOGY. 10, 1, 1932365.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  270. Influence of transfusions, hemodialysis and extracorporeal life support on hyperferritinemia in critically ill patients

    Knaak, C., Schuster, F. S., Nyvlt, P., Heeren, P., Spies, C., Schenk, T., La Rosée, P., Janka, G., Brunkhorst, F. M. & Lachmann, G., 2021, In: PLOS ONE. 16, 7, e0254345.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  271. Medulloblastoma tumor classification using deep transfer learning with multi-scale EfficientNets

    Bengs, M., Bockmayr, M., Schüller, U. & Schlaefer, A., 2021, In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE.

    Research output: SCORING: Contribution to journalConference article in journalResearchpeer-review

  272. 2020
  273. Young children with medulloblastoma: Important open questions and the high-risk dilemma

    Mynarek, M. & Rutkowski, S., 18.12.2020, In: NEURO-ONCOLOGY. 22, 12, p. 1723-1724 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  274. Evaluation of Prognostic Factors and Role of Participation in a Randomized Trial or a Prospective Registry in Pediatric and Adolescent Nonmetastatic Medulloblastoma - A Report From the HIT 2000 Trial

    Dietzsch, S., Placzek, F., Pietschmann, K., von Bueren, A. O., Matuschek, C., Glück, A., Guckenberger, M., Budach, V., Welzel, J., Pöttgen, C., Schmidberger, H., Heinzelmann, F., Paulsen, F., Escudero, M. P., Schwarz, R., Hornung, D., Martini, C., Grosu, A. L., Stueben, G., Jablonska, K., Dunst, J., Stranzl-Lawatsch, H., Dieckmann, K., Timmermann, B., Pietsch, T., Warmuth-Metz, M., Bison, B., Kwiecien, R., Benesch, M., Gerber, N. U., Grotzer, M. A., Pfister, S. M., Clifford, S. C., von Hoff, K., Klagges, S., Rutkowski, S., Kortmann, R-D. & Mynarek, M., 12.12.2020, In: ADV RADIAT ONCOL. 5, 6, p. 1158-1169 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  275. Stem Cell Transplantation and Vinblastine Monotherapy for Relapsed Pediatric Anaplastic Large Cell Lymphoma: Results of the International, Prospective ALCL-Relapse Trial

    Knörr, F., Brugières, L., Pillon, M., Zimmermann, M., Ruf, S., Attarbaschi, A., Mellgren, K., Burke, G. A. A., Uyttebroeck, A., Wróbel, G., Beishuizen, A., Aladjidi, N., Reiter, A. & Woessmann, W., 01.12.2020, In: J CLIN ONCOL. 38, 34, p. 3999-4009 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  276. Molecular characterization of CNS paragangliomas identifies cauda equina paragangliomas as a distinct tumor entity

    Schweizer, L., Thierfelder, F., Thomas, C., Soschinski, P., Suwala, A., Stichel, D., Wefers, A. K., Wessels, L., Misch, M., Kim, H-Y., Jödicke, R., Teichmann, D., Kaul, D., Kahn, J., Bockmayr, M., Hasselblatt, M., Younsi, A., Unterberg, A., Knie, B., Walter, J., Al Safatli, D., May, S-A., Jödicke, A., Ntoulias, G., Moskopp, D., Vajkoczy, P., Heppner, F. L., Capper, D., Hartmann, W., Hartmann, C., von Deimling, A., Reuss, D. E., Schöler, A. & Koch, A., 12.2020, In: ACTA NEUROPATHOL. 140, 6, p. 893-906 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  277. Mucopolysaccharidosis type I due to maternal uniparental disomy of chromosome 4 with partial isodisomy of 4p16.3p15.2

    Kloth, K., Vater, I., Lindschau, R., Rau, I., Caliebe, A. & Muschol, N. M., 12.2020, In: MOL GENET METAB REP. 25, 100660.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  278. Treatment response of CNS high-grade neuroepithelial tumors with MN1 alteration

    Baroni, L. V., Rugilo, C., Lubieniecki, F., Sampor, C., Freytes, C., Nobre, L., Hansford, J. R., Malalasekera, V. S., Zapotocky, M., Dodgshun, A., Martinez, O. C., La Madrid, A. M., Lavarino, C., Suñol, M., Rutkowski, S., Schuller, U., Bouffet, E., Ramaswamy, V. & Alderete, D., 12.2020, In: PEDIATR BLOOD CANCER. 67, 12, p. e28627

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  279. Ependymomas in infancy: underlying genetic alterations, histological features, and clinical outcome

    Jünger, S. T., Andreiuolo, F., Mynarek, M., Dörner, E., Zur Mühlen, A., Rutkowski, S., von Bueren, A. O. & Pietsch, T., 11.2020, In: CHILD NERV SYST. 36, 11, p. 2693-2700 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  280. Impact of COVID-19 pandemic on mental health of patients with inherited bleeding disorders in Germany

    von Mackensen, S., Halimeh, S., Siebert, M., Wermes, C., Hassenpflug, W., Holstein, K. & Olivieri, M., 11.2020, In: HAEMOPHILIA. 26, 6, p. e272-e281

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  281. Glioma escape signature and clonal development under immune pressure

    Maire, C. L., Mohme, M., Bockmayr, M., Fita, K. D., Riecken, K., Börnigen, D., Alawi, M., Failla, A. V., Kolbe, K., Zapf, S., Holz, M., Neumann, K., Dührsen, L., Lange, T., Fehse, B., Westphal, M. & Lamszus, K., 01.10.2020, In: J CLIN INVEST. 130, 10, p. 5257-5271 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  282. IL10RA modulates crizotinib sensitivity in NPM1-ALK+ anaplastic large cell lymphoma

    Prokoph, N., Probst, N. A., Lee, L. C., Monahan, J. M., Matthews, J. D., Liang, H-C., Bahnsen, K., Montes-Mojarro, I. A., Karaca Atabay, E., Sharma, G. G., Malik, V., Larose, H., Forde, S. D., Ducray, S. P., Lobello, C., Wang, Q., Luan, S-L., Pospisilova, S., Gambacorti-Passerini, C. B., Burke, A., Pervez, S., Attarbaschi, A., Janikova, A., Pacquement, H., Landman-Parker, J., Lambilliotte, A., Schleiermacher, G., Klapper, W., Jauch, R., Woessmann, W., Vassal, G., Kenner, L., Merkel, O., Mologni, L., Chiarle, R., Brugieres, L., Geoerger, B., Barbieri, I. & Turner, S. D., 01.10.2020, In: BLOOD. 136, 14, p. 1657-1669 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  283. A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome

    Drivas, T. G., Li, D., Nair, D., Alaimo, J. T., Alders, M., Altmüller, J., Barakat, T. S., Bebin, E. M., Bertsch, N. L., Blackburn, P. R., Blesson, A., Bouman, A. M., Brockmann, K., Brunelle, P., Burmeister, M., Cooper, G. M., Denecke, J., Dieux-Coëslier, A., Dubbs, H., Ferrer, A., Gal, D., Bartik, L. E., Gunderson, L. B., Hasadsri, L., Jain, M., Karimov, C., Keena, B., Klee, E. W., Kloth, K., Lace, B., Macchiaiolo, M., Marcadier, J. L., Milunsky, J. M., Napier, M. P., Ortiz-Gonzalez, X. R., Pichurin, P. N., Pinner, J., Powis, Z., Prasad, C., Radio, F. C., Rasmussen, K. J., Renaud, D. L., Rush, E. T., Saunders, C., Selcen, D., Seman, A. R., Shinde, D. N., Smith, E. D., Smol, T., Snijders Blok, L., Stoler, J. M., Tang, S., Tartaglia, M., Thompson, M. L., van de Kamp, J. M., Wang, J., Weise, D., Weiss, K., Woitschach, R., Wollnik, B., Yan, H., Zackai, E. H., Zampino, G., Campeau, P. & Bhoj, E., 10.2020, In: EUR J HUM GENET. 28, 10, p. 1422-1431 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  284. Comparison of von Willebrand factor platelet-binding activity assays: ELISA overreads type 2B with loss of HMW multimers

    Szederjesi, A., Baronciani, L., Budde, U., Castaman, G., Colpani, P., Lawrie, A. S., Liu, Y., Montgomery, R., Peyvandi, F., Schneppenheim, R., Patzke, J. & Bodó, I., 10.2020, In: J THROMB HAEMOST. 18, 10, p. 2513-2523 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  285. Fear of progression in parents of childhood cancer survivors: A Dyadic data analysis

    Peikert, M. L., Inhestern, L., Krauth, K. A., Escherich, G., Rutkowski, S., Kandels, D. & Bergelt, C., 10.2020, In: PSYCHO-ONCOLOGY. 29, 10, p. 1678-1685 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  286. Heterogeneous phenotypes in families with duplications of the paternal allele within the imprinting center 1 (H19/IGF2:TSS-DMR) in 11p15.5

    Eggermann, T., Kraft, F., Kloth, K., Klopocki, E., Hüning, I., Hempel, M. & Kunstmann, E., 10.2020, In: CLIN GENET. 98, 4, p. 418-419 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  287. Leukemia-induced dysfunctional TIM-3+CD4+ bone marrow T cells increase risk of relapse in pediatric B-precursor ALL patients

    Blaeschke, F., Willier, S., Stenger, D., Lepenies, M., Horstmann, M. A., Escherich, G., Zimmermann, M., Rojas Ringeling, F., Canzar, S., Kaeuferle, T., Rohlfs, M., Binder, V., Klein, C. & Feuchtinger, T., 10.2020, In: LEUKEMIA. 34, 10, p. 2607-2620 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  288. Multiclass cancer classification in fresh frozen and formalin-fixed paraffin-embedded tissue by DigiWest multiplex protein analysis

    Bockmayr, T., Erdmann, G., Treue, D., Jurmeister, P., Schneider, J., Arndt, A., Heim, D., Bockmayr, M., Sachse, C. & Klauschen, F., 10.2020, In: LAB INVEST. 100, 10, p. 1288-1299 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  289. Successful Stem Cell Apheresis Using Spectra Optia in a 6 kg Child With Atypical Teratoid/Rhabdoid Tumor

    Brust, P., Schubert, C., Blohm, M. & Winkler, B., 10.2020, In: J PEDIAT HEMATOL ONC. 42, 7, p. e692-e695

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  290. Treosulfan-fludarabine-thiotepa-based conditioning treatment before allogeneic hematopoietic stem cell transplantation for pediatric patients with hematological malignancies

    Kalwak, K., Mielcarek, M., Patrick, K., Styczynski, J., Bader, P., Corbacioglu, S., Burkhardt, B., Sykora, K. W., Drabko, K., Gozdzik, J., Fagioli, F., Greil, J., Gruhn, B., Beier, R., Locatelli, F., Müller, I., Schlegel, P. G., Sedlacek, P., Stachel, K. D., Hemmelmann, C., Möller, A-K., Baumgart, J. & Vora, A., 10.2020, In: BONE MARROW TRANSPL. 55, 10, p. 1996-2007 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  291. Long-term cognitive deficits in pediatric low-grade glioma (LGG) survivors reflect pretreatment conditions-report from the German LGG studies

    Traunwieser, T., Kandels, D., Pauls, F., Pietsch, T., Warmuth-Metz, M., Bison, B., Krauss, J., Kortmann, R-D., Timmermann, B., Thomale, U-W., Luettich, P., Neumann-Holbeck, A., Tischler, T., Hernáiz Driever, P., Witt, O. & Gnekow, A. K., 25.09.2020, In: NEURO-ONCOL ADV. 2, 1, vdaa094.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  292. Prognostic Factors in Childhood Anaplastic Large Cell Lymphoma: Long Term Results of the International ALCL99 Trial

    Mussolin, L., Le Deley, M-C., Carraro, E., Damm-Welk, C., Attarbaschi, A., Williams, D., Burke, A., Horibe, K., Nakazawa, A., Wrobel, G., Mann, G., Csóka, M., Uyttebroeck, A., Fernández-Delgado Cerdá, R. F-D., Beishuizen, A., Mellgren, K., Burkhardt, B., Klapper, W., Turner, S. D., D'Amore, E. S. G., Lamant, L., Reiter, A., Woessmann, W., Brugières, L. & Pillon, M. P. O. B. O. T. E. I-G. F. C. N-H. L., 24.09.2020, In: CANCERS. 12, 10

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  293. Platelet adhesion and aggregate formation controlled by immobilised and soluble VWF

    Schneider, M. F., Fallah, M. A., Mess, C., Obser, T., Schneppenheim, R., Alexander-Katz, A., Schneider, S. W. & Huck, V., 11.09.2020, In: BMC MOL CELL BIOL. 21, 1, p. 64

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  294. Chromatin accessibility landscape of pediatric T-lymphoblastic leukemia and human T-cell precursors

    Erarslan-Uysal, B., Kunz, J. B., Rausch, T., Richter-Pechańska, P., van Belzen, I. A., Frismantas, V., Bornhauser, B., Ordoñez-Rueada, D., Paulsen, M., Benes, V., Stanulla, M., Schrappe, M., Cario, G., Escherich, G., Bakharevich, K., Kirschner-Schwabe, R., Eckert, C., Loukanov, T., Gorenflo, M., Waszak, S. M., Bourquin, J-P., Muckenthaler, M. U., Korbel, J. O. & Kulozik, A. E., 07.09.2020, In: EMBO MOL MED. 12, 9, p. e12104

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  295. Early clinical course after hematopoietic stem cell transplantation in children with juvenile metachromatic leukodystrophy

    Beschle, J., Döring, M., Kehrer, C., Raabe, C., Bayha, U., Strölin, M., Böhringer, J., Bevot, A., Kaiser, N., Bender, B., Grimm, A., Lang, P., Müller, I., Krägeloh-Mann, I. & Groeschel, S., 03.09.2020, In: Molecular and cellular pediatrics. 7, 1, p. 12

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  296. Bleeding symptoms in patients diagnosed as type 3 von Willebrand disease: Results from 3WINTERS-IPS, an international and collaborative cross-sectional study

    Tosetto, A., Badiee, Z., Baghaipour, M-R., Baronciani, L., Battle, J., Berntorp, E., Bodó, I., Budde, U., Castaman, G., Eikenboom, J. C. J., Eshghi, P., Ettorre, C., Goodeve, A., Goudemand, J., Hay, C. R. M., Hoorfar, H., Karimi, M., Keikhaei, B., Lassila, R., Leebeek, F. W. G., Lopez Fernandez, M. F., Mannucci, P. M., Mazzucconi, M. G., Morfini, M., Oldenburg, J., Peake, I., Parra Lòpez, R., Peyvandi, F., Schneppenheim, R., Tiede, A., Toogeh, G., Trossaert, M., Zekavat, O., Zetterberg, E. M. K. & Federici, A. B., 09.2020, In: J THROMB HAEMOST. 18, 9, p. 2145-2154 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  297. CDKN2A deletion in supratentorial ependymoma with RELA alteration indicates a dismal prognosis: a retrospective analysis of the HIT ependymoma trial cohort

    Jünger, S. T., Andreiuolo, F., Mynarek, M., Wohlers, I., Rahmann, S., Klein-Hitpass, L., Dörner, E., Zur Mühlen, A., Velez-Char, N., von Hoff, K., Warmuth-Metz, M., Kortmann, R-D., Timmermann, B., von Bueren, A., Rutkowski, S. & Pietsch, T., 09.2020, In: ACTA NEUROPATHOL. 140, 3, p. 405-407 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  298. Experience with provisional WHO-entities large B-cell lymphoma with IRF4-rearrangement and Burkitt-like lymphoma with 11q aberration in paediatric patients of the NHL-BFM group

    Au-Yeung, R. K. H., Arias Padilla, L., Zimmermann, M., Oschlies, I., Siebert, R., Woessmann, W., Burkhardt, B. & Klapper, W., 09.2020, In: BRIT J HAEMATOL. 190, 5, p. 753-763 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  299. Risk factors for mixed chimerism in children with hemophagocytic lymphohistiocytosis after reduced toxicity conditioning

    Wustrau, K., Greil, J., Sykora, K-W., Albert, M. H., Burkhardt, B., Lang, P., Meisel, R., Wössmann, W., Beier, R., Schulz, A., Bader, P., Chada, M., Kühl, J-S., Schlegel, P-G., Speckmann, C., Gruhn, B., Seidel, M., Wawer, A., Ozga, A-K., Janka, G., Ehl, S., Müller, I. & Lehmberg, K., 09.2020, In: PEDIATR BLOOD CANCER. 67, 9, p. e28523

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  300. Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions

    Starzonek, S., Maar, H., Labitzky, V., Wicklein, D., Rossdam, C., Buettner, F. F. R., Wolters-Eisfeld, G., Guengoer, C., Wagener, C., Schumacher, U. & Lange, T., 20.08.2020, In: GLYCOBIOLOGY. 30, 9, p. 695-709 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  301. Juvenile Blastic Plasmacytoid Dendritic Cell Neoplasm

    Hayani, K. M., Escherich, G., Koch, K., French, L. E. & Wolff, H. H., 18.08.2020, In: ACTA DERM-VENEREOL. 100, 15, p. adv00245

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  302. Stem cell transplantation for children with hemophagocytic lymphohistiocytosis: results from the HLH-2004 study

    Bergsten, E., Horne, A., Hed Myrberg, I., Aricó, M., Astigarraga, I., Ishii, E., Janka, G., Ladisch, S., Lehmberg, K., McClain, K. L., Minkov, M., Nanduri, V., Rosso, D. A., Sieni, E., Winiarski, J. & Henter, J-I., 11.08.2020, In: BLOOD ADV. 4, 15, p. 3754-3766 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  303. Neuroinflammatory Disease as an Isolated Manifestation of Hemophagocytic Lymphohistiocytosis

    Blincoe, A., Heeg, M., Campbell, P. K., Hines, M., Khojah, A., Klein-Gitelman, M., Talano, J-A., Speckmann, C., Touzot, F., Lankester, A., Legger, G. E., Rivière, J. G., Garcia-Prat, M., Alonso, L., Putti, M. C., Lehmberg, K., Maier, S., El Chazli, Y., Elmaksoud, M. A., Astigarraga, I., Kurjane, N., Bulina, I., Kenina, V., Bryceson, Y., Rascon, J., Lortie, A., Goldstein, G., Booth, C., Worth, A., Wassmer, E., Schmitt, E. G., Warren, J. T., Bednarski, J. J., Ali, S., Chiang, K-Y., Krueger, J., Henry, M. M., Holland, S. M., Marsh, R. A., Ehl, S. & Haddad, E., 08.2020, In: J CLIN IMMUNOL. 40, 6, p. 901-916 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  304. Rare non-Hodgkin lymphoma of childhood and adolescence: A consensus diagnostic and therapeutic approach to pediatric-type follicular lymphoma, marginal zone lymphoma, and nonanaplastic peripheral T-cell lymphoma

    Attarbaschi, A., Abla, O., Arias Padilla, L., Beishuizen, A., Burke, G. A. A., Brugières, L., Bruneau, J., Burkhardt, B., d'Amore, E. S. G., Klapper, W., Kontny, U., Pillon, M., Taj, M., Turner, S. D., Uyttebroeck, A., Woessmann, W. & Mellgren, K., 08.2020, In: PEDIATR BLOOD CANCER. 67, 8, p. e28416

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  305. DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions

    Sandoval-Pérez, A., Berger, R. M. L., Garaizar, A., Farr, S. E., Brehm, M. A., König, G., Schneider, S. W., Collepardo-Guevara, R., Huck, V., Rädler, J. O. & Aponte-Santamaría, C., 27.07.2020, In: NUCLEIC ACIDS RES. 48, 13, p. 7333-7344 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  306. Age and DNA-methylation subgroup as potential independent risk factors for treatment stratification in children with Atypical Teratoid/Rhabdoid Tumors (ATRT)

    Frühwald, M. C., Hasselblatt, M., Nemes, K., Bens, S., Steinbügl, M., Johann, P. D., Kerl, K., Hauser, P., Quiroga, E., Solano-Paez, P., Biassoni, V., Gil-da-Costa, M. J., Perek-Polnik, M., van de Wetering, M., Sumerauer, D., Pears, J., Stabell, N., Holm, S., Hengartner, H., Gerber, N. U., Grotzer, M., Boos, J., Ebinger, M., Tippelt, S., Paulus, W., Furtwängler, R., Hernáiz-Driever, P., Reinhard, H., Rutkowski, S., Schlegel, P-G., Schmid, I., Kortmann, R-D., Timmermann, B., Warmuth-Metz, M., Kordes, U., Gerss, J., Nysom, K., Schneppenheim, R., Siebert, R., Kool, M. & Graf, N., 07.07.2020, In: NEURO-ONCOLOGY. 22, 7, p. 1006–1017 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  307. Genome-wide DNA methylation profiles distinguish silent from non-silent ACTH adenomas

    Ricklefs, F. L., Fita, K. D., Rotermund, R., Piffko, A., Schmid, S., Capper, D., Buslei, R., Buchfelder, M., Burkhardt, T., Matschke, J., Lamszus, K., Westphal, M., Schüller, U. & Flitsch, J., 07.2020, In: ACTA NEUROPATHOL. 140, 1, p. 95-97 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  308. Incidence of SCID in Germany from 2014 to 2015 an ESPED* Survey on Behalf of the API*** Erhebungseinheit für Seltene Pädiatrische Erkrankungen in Deutschland (German Paediatric Surveillance Unit) ** Arbeitsgemeinschaft Pädiatrische Immunologie

    Shai, S., Perez-Becker, R., Andres, O., Bakhtiar, S., Bauman, U., von Bernuth, H., Classen, C-F., Dückers, G., El-Helou, S. M., Gangfuß, A., Ghosh, S., Grimbacher, B., Hauck, F., Hoenig, M., Husain, R. A., Kindle, G., Kipfmueller, F., Klemann, C., Krüger, R., Lainka, E., Lehmberg, K., Lohrmann, F., Morbach, H., Naumann-Bartsch, N., Oommen, P. T., Schulz, A., Seidemann, K., Speckmann, C., Sykora, K-W., von Kries, R. & Niehues, T., 07.2020, In: J CLIN IMMUNOL. 40, 5, p. 708-717 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  309. Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

    Clarke, M., Mackay, A., Ismer, B., Pickles, J. C., Tatevossian, R. G., Newman, S., Bale, T. A., Stoler, I., Izquierdo, E., Temelso, S., Carvalho, D. M., Molinari, V., Burford, A., Howell, L., Virasami, A., Fairchild, A. R., Avery, A., Chalker, J., Kristiansen, M., Haupfear, K., Dalton, J. D., Orisme, W., Wen, J., Hubank, M., Kurian, K. M., Rowe, C., Maybury, M., Crosier, S., Knipstein, J., Schuller, U., Kordes, U., Kram, D. E., Snuderl, M., Bridges, L., Martin, A. J., Doey, L. J., Al-Sarraj, S., Chandler, C., Zebian, B., Cairns, C., Natrajan, R., Boult, J. K., Robinson, S. P., Sill, M., Dunkel, I. J., Gilheeney, S. W., Rosenblum, M. K., Hughes, D., Proszek, P. Z., MacDonald, T. J., Preusser, M., Haberler, C., Slavc, I., Packer, R., Ng, H-K., Caspi, S., Popovic, M., Faganel Kotnik, B., Wood, M. D., Baird, L., Davare, M. A., Solomon, D. A., Olsen, T. K., Brandal, P., Farrell, M., Cryan, J. B., Capra, M., Karremann, M., Schittenhelm, J., Schuhmann, M. U., Ebinger, M., Dinjens, W. N. M., Kerl, K., Hettmer, S., Pietsch, T., Andreiuolo, F., Driever, P. H., Korshunov, A., Hiddingh, L., Worst, B. C., Sturm, D., Zuckermann, M., Witt, O., Bloom, T., Mitchell, C., Miele, E., Colafati, G. S., Diomedi-Camassei, F., Bailey, S., Moore, A. S., Hassall, T. E., Lowis, S. P., Tsoli, M., Cowley, M. J., Ziegler, D. S., Karajannis, M. A., Aquilina, K., Hargrave, D. R., Carceller, F., Marshall, L. V., von Deimling, A., Kramm, C. M., Pfister, S. M., Sahm, F., Baker, S. J., Mastronuzzi, A., Carai, A., Vinci, M., Capper, D., Popov, S., Ellison, D. W., Jacques, T. S., Jones, D. T. W. & Jones, C., 07.2020, In: CANCER DISCOV. 10, 7, p. 942-963 22 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  310. Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort

    Mynarek, M., von Hoff, K., Pietsch, T., Ottensmeier, H., Warmuth-Metz, M., Bison, B., Pfister, S., Korshunov, A., Sharma, T., Jaeger, N., Ryzhova, M., Zheludkova, O., Golanov, A., Rushing, E. J., Hasselblatt, M., Koch, A., Schüller, U., von Deimling, A., Sahm, F., Sill, M., Riemenschneider, M. J., Dohmen, H., Monoranu, C. M., Sommer, C., Staszewski, O., Mawrin, C., Schittenhelm, J., Brück, W., Filipski, K., Hartmann, C., Meinhardt, M., Pietschmann, K., Haberler, C., Slavc, I., Gerber, N. U., Grotzer, M., Benesch, M., Schlegel, P. G., Deinlein, F., von Bueren, A. O., Friedrich, C., Juhnke, B-O., Obrecht, D., Fleischhack, G., Kwiecien, R., Faldum, A., Kortmann, R. D., Kool, M. & Rutkowski, S., 20.06.2020, In: J CLIN ONCOL. 38, 18, p. 2028-2040 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  311. Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment

    Hrusak, O., Kalina, T., Wolf, J., Balduzzi, A., Provenzi, M., Rizzari, C., Rives, S., Del Pozo Carlavilla, M., Alonso, M. E. V., Domínguez-Pinilla, N., Bourquin, J-P., Schmiegelow, K., Attarbaschi, A., Grillner, P., Mellgren, K., van der Werff Ten Bosch, J., Pieters, R., Brozou, T., Borkhardt, A., Escherich, G., Lauten, M., Stanulla, M., Smith, O., Yeoh, A. E. J., Elitzur, S., Vora, A., Li, C-K., Ariffin, H., Kolenova, A., Dallapozza, L., Farah, R., Lazic, J., Manabe, A., Styczynski, J., Kovacs, G., Ottoffy, G., Felice, M. S., Buldini, B., Conter, V., Stary, J. & Schrappe, M., 06.2020, In: EUR J CANCER. 132, p. 11-16 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  312. Hemophagocytic Lymphohistiocytosis in Critically Ill Patients

    Knaak, C., Schuster, F. S., Spies, C., Vorderwülbecke, G., Nyvlt, P., Schenk, T., Balzer, F., La Rosée, P., Janka, G., Brunkhorst, F. M., Keh, D. & Lachmann, G., 06.2020, In: SHOCK. 53, 6, p. 701-709 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  313. Influence of anti-thymocyte globulin plasma levels on outcome parameters in stem cell transplanted children

    Vogelsang, V., Kruchen, A., Wustrau, K., Spohn, M. & Müller, I., 06.2020, In: INT IMMUNOPHARMACOL. 83, p. 106371

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  314. The basic helix-loop-helix transcription factor TCF4 impacts brain architecture as well as neuronal morphology and differentiation

    Schoof, M., Hellwig, M., Harrison, L., Holdhof, D., Lauffer, M. C., Niesen, J., Virdi, S., Indenbirken, D. & Schüller, U., 06.2020, In: EUR J NEUROSCI. 51, 11, p. 2219-2235 17 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  315. Can we optimise doxorubicin treatment regimens for children with cancer? Pharmacokinetic simulations and a Delphi consensus procedure

    Siebel, C., Würthwein, G., Lanvers-Kaminsky, C., André, N., Berthold, F., Castelli, I., Chastagner, P., Doz, F., English, M., Escherich, G., Frühwald, M. C., Graf, N., Groll, A. H., Ruggiero, A., Hempel, G. & Boos, J., 28.05.2020, In: BMC PHARMACOL TOXICO. 21, 1, p. 37

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  316. Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore

    Knaak, C., Nyvlt, P., Schuster, F. S., Spies, C., Heeren, P., Schenk, T., Balzer, F., La Rosée, P., Janka, G., Brunkhorst, F. M., Keh, D. & Lachmann, G., 24.05.2020, In: CRIT CARE. 24, 1, p. 244

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  317. Targeted busulfan-based reduced-intensity conditioning and HLA-matched HSCT cure hemophagocytic lymphohistiocytosis

    Felber, M., Steward, C. G., Kentouche, K., Fasth, A., Wynn, R. F., Zeilhofer, U., Haunerdinger, V., Volkmer, B., Prader, S., Gruhn, B., Ehl, S., Lehmberg, K., Müller, D., Gennery, A. R., Albert, M. H., Hauck, F., Rao, K., Veys, P., Hassan, M., Lankester, A. C., Schmid, J. P., Hauri-Hohl, M. M. & Güngör, T., 12.05.2020, In: BLOOD ADV. 4, 9, p. 1998-2010 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  318. Pik3ca mutations significantly enhance the growth of Shh medulloblastoma and lead to metastatic tumour growth in a novel mouse model

    Niesen, J., Ohli, J., Sedlacik, J., Dührsen, L., Hellwig, M., Spohn, M., Holsten, T. & Schüller, U., 01.05.2020, In: CANCER LETT. 477, p. 10-18 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  319. An 8-Year-Old Girl with Posterior Fossa Mass

    Ruf, V. C., Schöler, A., Capper, D., Arzberger, T., Herms, J. & Schüller, U., 05.2020, In: BRAIN PATHOL. 30, 3, p. 713-714 2 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  320. Epigenetics impacts upon prognosis and clinical management of choroid plexus tumors

    Thomas, C., Metrock, K., Kordes, U., Hasselblatt, M. & Dhall, G., 05.2020, In: J NEURO-ONCOL. 148, 1, p. 39-45 7 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  321. Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance

    Melcher, V., Graf, M., Interlandi, M., Moreno, N., de Faria, F. W., Kim, S. N., Kastrati, D., Korbanka, S., Alfert, A., Gerß, J., Meyer Zu Hörste, G., Hartmann, W., Frühwald, M. C., Dugas, M., Schüller, U., Hasselblatt, M., Albert, T. K. & Kerl, K., 05.2020, In: ACTA NEUROPATHOL. 139, 5, p. 913-936 24 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  322. Preferential sensitivity to HDAC inhibitors in tumors with CREBBP mutation

    Hellwig, M., Merk, D. J., Lutz, B. & Schüller, U., 05.2020, In: CANCER GENE THER. 27, 5, p. 294-300 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  323. Register und Studien in der Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH) – Welchen Beitrag leisten sie zum Fortschritt?

    Klingebiel, T., Jürgens, H., Glauche, I., Gnekow, A., Kandels, D., Woessmann, W., Schneider, D. T. & Suttorp, M., 05.2020, In: KLIN PADIATR. 232, 3, p. 124-135 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  324. Favorable outcomes of hematopoietic stem cell transplantation in children and adolescents with Diamond-Blackfan anemia

    Strahm, B., Loewecke, F., Niemeyer, C. M., Albert, M., Ansari, M., Bader, P., Bertrand, Y., Burkhardt, B., Da Costa, L. M., Ferster, A., Fischer, A., Güngör, T., Gruhn, B., Hainmann, I., Kapp, F., Lang, P., Müller, I., Schulz, A., Szvetnik, A., Wlodarski, M., Noellke, P., Leblanc, T. & Dalle, J-H., 28.04.2020, In: BLOOD ADV. 4, 8, p. 1760-1769 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  325. A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia

    Enshaei, A., O'Connor, D., Bartram, J., Hancock, J., Harrison, C. J., Hough, R., Samarasinghe, S., den Boer, M. L., Boer, J. M., de Groot-Kruseman, H. A., Marquart, H. V., Noren-Nystrom, U., Schmiegelow, K., Schwab, C., Horstmann, M. A., Escherich, G., Heyman, M., Pieters, R., Vora, A., Moppett, J. & Moorman, A. V., 23.04.2020, In: BLOOD. 135, 17, p. 1438-1446 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  326. Resolving challenges in deep learning-based analyses of histopathological images using explanation methods

    Hägele, M., Seegerer, P., Lapuschkin, S., Bockmayr, M., Samek, W., Klauschen, F., Müller, K-R. & Binder, A., 14.04.2020, In: SCI REP-UK. 10, 1, p. 6423

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  327. Progressive or relapsed Burkitt lymphoma or leukemia in children and adolescents after BFM-type first-line therapy

    Woessmann, W., Zimmermann, M., Meinhardt, A., Müller, S., Hauch, H., Knörr, F., Oschlies, I., Klapper, W., Niggli, F., Kabickova, E., Attarbaschi, A., Reiter, A. & Burkhardt, B., 02.04.2020, In: BLOOD. 135, 14, p. 1124-1132 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  328. genBaRcode - a comprehensive R package for genetic barcode analysis

    Thielecke, L., Cornils, K. & Glauche, I., 01.04.2020, In: BIOINFORMATICS. 36, 7, p. 2189-2194 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  329. Effects of the growth pattern of medulloblastoma on short-term neurological impairments after surgery: results from the prospective multicenter HIT-SIOP PNET 4 study

    Schepke, E., Tisell, M., Kennedy, C., Puget, S., Ferroli, P., Chevignard, M., Doz, F., Pizer, B., Rutkowski, S., Massimino, M., Navajas, A., Schwalbe, E., Hicks, D., Clifford, S. C., Pietsch, T. & Lannering, B., 04.2020, In: Journal of neurosurgery. Pediatrics. p. 1-9 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  330. EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma

    Struve, N., Binder, Z. A., Stead, L. F., Brend, T., Bagley, S. J., Faulkner, C., Ott, L., Müller-Goebel, J., Weik, A-S., Hoffer, K., Krug, L., Rieckmann, T., Bußmann, L., Henze, M., Morrissette, J. J. D., Kurian, K. M., Schüller, U., Petersen, C., Rothkamm, K., O Rourke, D. M., Short, S. C. & Kriegs, M., 04.2020, In: ONCOGENE. 39, 15, p. 3041-3055 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  331. Germline Elongator mutations in Sonic Hedgehog medulloblastoma

    Waszak, S. M., Robinson, G. W., Gudenas, B. L., Smith, K. S., Forget, A., Kojic, M., Garcia-Lopez, J., Hadley, J., Hamilton, K. V., Indersie, E., Buchhalter, I., Kerssemakers, J., Jäger, N., Sharma, T., Rausch, T., Kool, M., Sturm, D., Jones, D. T. W., Vasilyeva, A., Tatevossian, R. G., Neale, G., Lombard, B., Loew, D., Nakitandwe, J., Rusch, M., Bowers, D. C., Bendel, A., Partap, S., Chintagumpala, M., Crawford, J., Gottardo, N. G., Smith, A., Dufour, C., Rutkowski, S., Eggen, T., Wesenberg, F., Kjaerheim, K., Feychting, M., Lannering, B., Schüz, J., Johansen, C., Andersen, T. V., Röösli, M., Kuehni, C. E., Grotzer, M., Remke, M., Puget, S., Pajtler, K. W., Milde, T., Witt, O., Ryzhova, M., Korshunov, A., Orr, B. A., Ellison, D. W., Brugieres, L., Lichter, P., Nichols, K. E., Gajjar, A., Wainwright, B. J., Ayrault, O., Korbel, J. O., Northcott, P. A. & Pfister, S. M., 04.2020, In: NATURE. 580, 7803, p. 396-401 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  332. Hemophagocytic lymphohistiocytosis in adults: collaborative analysis of 137 cases of a nationwide German registry

    Birndt, S., Schenk, T., Heinevetter, B., Brunkhorst, F. M., Maschmeyer, G., Rothmann, F., Weber, T., Müller, M., Panse, J., Penack, O., Schroers, R., Braess, J., Frickhofen, N., Ehl, S., Janka, G., Lehmberg, K., Pletz, M. W., Hochhaus, A., Ernst, T. & La Rosée, P., 04.2020, In: J CANCER RES CLIN. 146, 4, p. 1065-1077 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  333. Hyperferritinemia in Critically Ill Patients

    Lachmann, G., Knaak, C., Vorderwülbecke, G., La Rosée, P., Balzer, F., Schenk, T., Schuster, F. S., Nyvlt, P., Janka, G., Brunkhorst, F. M., Keh, D. & Spies, C., 04.2020, In: CRIT CARE MED. 48, 4, p. 459-465 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  334. Synovial sarcoma disease characteristics and primary tumor sites differ between patient age groups: a report of the Cooperative Weichteilsarkom Studiengruppe (CWS)

    Scheer, M., Blank, B., Bauer, S., Vokuhl, C., Stegmaier, S., Feuchtgruber, S., Henssen, A., Sparber-Sauer, M., Eggert, A., Handgretinger, R., Pekrun, A., Rossig, C., Rutkowski, S., Schlegel, P-G., Schrappe, M., Simon, T., Kazanowska, B., Niggli, F., Ladenstein, R., Ljungman, G., Jahnukainen, K., Fuchs, J., Bielack, S. S., Koscielniak, E., Klingebiel, T. & Cooperative Weichteilsarkom Studiengruppe [CWS], 04.2020, In: J CANCER RES CLIN. 146, 4, p. 953-960 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  335. hGFAP-Positive Stem Cells Depend on Brg1 for Proper Formation of Cerebral and Cerebellar Structures

    Holdhof, D., Schoof, M., Hellwig, M., Holdhof, N. H., Niesen, J. & Schüller, U., 14.03.2020, In: CEREB CORTEX. 30, 3, p. 1382-1392 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  336. Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape

    Mohme, M., Maire, C. L., Schliffke, S., Joosse, S. A., Alawi, M., Matschke, J., Schüller, U., Dierlamm, J., Martens, T., Pantel, K., Riethdorf, S., Lamszus, K. & Westphal, M., 09.03.2020, In: ACTA NEUROPATHOL COM. 8, 1, 28.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  337. Returning to daily life: a qualitative interview study on parents of childhood cancer survivors in Germany

    Peikert, M. L., Inhestern, L., Krauth, K. A., Escherich, G., Rutkowski, S., Kandels, D. & Bergelt, C., 08.03.2020, In: BMJ OPEN. 10, 3, p. e033730

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  338. A multi-omics approach reveals mechanisms of nanomaterial toxicity and structure-activity relationships in alveolar macrophages

    Bannuscher, A., Karkossa, I., Buhs, S., Nollau, P., Kettler, K., Balas, M., Dinischiotu, A., Hellack, B., Wiemann, M., Luch, A., von Bergen, M., Haase, A. & Schubert, K., 03.2020, In: NANOTOXICOLOGY. 14, 2, p. 181-195 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  339. Cerebrospinal fluid evaluation in adult patients with medulloblastoma

    von Bueren, A. O., Hagel, C. & Rutkowski, S., 03.2020, In: LANCET ONCOL. 21, 3, p. e120

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  340. Treatment and outcome of IG-MYC+ neoplasms with precursor B-cell phenotype in childhood and adolescence

    Herbrueggen, H., Mueller, S., Rohde, J., Arias Padilla, L., Moericke, A., Attarbaschi, A., Zimmermann, M., Ratei, R., Brueggemann, M., Siebert, R., Goehring, G., Schlegelberger, B., Bradtke, J., Klapper, W., Woessmann, W. & Burkhardt, B., 03.2020, In: LEUKEMIA. 34, 3, p. 942-946 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  341. Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults

    Thomas, C., Wefers, A., Bens, S., Nemes, K., Agaimy, A., Oyen, F., Vogelgesang, S., Rodriguez, F. J., Brett, F. M., McLendon, R., Bodi, I., Burel-Vandenbos, F., Keyvani, K., Tippelt, S., Poulsen, F. R., Lipp, E. S., Giannini, C., Reifenberger, G., Kuchelmeister, K., Pietsch, T., Kordes, U., Siebert, R., Frühwald, M. C., Johann, P. D., Sill, M., Kool, M., von Deimling, A., Paulus, W. & Hasselblatt, M., 02.2020, In: ACTA NEUROPATHOL. 139, 2, p. 277-286 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  342. Genome-wide analysis of acute leukemia and clonally related histiocytic sarcoma in a series of three pediatric patients

    Bleeke, M., Johann, P., Gröbner, S., Alten, J., Cario, G., Schäfer, H., Klapper, W., Khoury, J., Pfister, S. & Müller, I., 02.2020, In: PEDIATR BLOOD CANCER. 67, 2, p. e28074

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  343. Hematopoietic stem cell transplantation for children with acute myeloid leukemia-results of the AML SCT-BFM 2007 trial

    Sauer, M. G., Lang, P. J., Albert, M. H., Bader, P., Creutzig, U., Eyrich, M., Greil, J., Gruhn, B., Holter, W., Klingebiel, T., Kremens, B., von der Leyen, H., Mauz-Körholz, C., Meisel, R., Mischke, K., Müller, I., Niemeyer, C. M., Peters, C., Pohler, C., Reinhardt, D., Burkhardt, B., Schlegel, P. G., Schulz, A. S., Schrum, J., Sedlacek, P., Strahm, B., Woessmann, W., Handgretinger, R., Zimmermann, M. & Borkhardt, A., 02.2020, In: LEUKEMIA. 34, 2, p. 613-624 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  344. Molecular characterization of histopathological ependymoma variants

    Neumann, J. E., Spohn, M., Obrecht, D., Mynarek, M., Thomas, C., Hasselblatt, M., Dorostkar, M. M., Wefers, A. K., Frank, S., Monoranu, C-M., Koch, A., Witt, H., Kool, M., Pajtler, K. W., Rutkowski, S., Glatzel, M. & Schüller, U., 02.2020, In: ACTA NEUROPATHOL. 139, 2, p. 305-318 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  345. Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations

    Pfaff, E., Aichmüller, C., Sill, M., Stichel, D., Snuderl, M., Karajannis, M. A., Schuhmann, M. U., Schittenhelm, J., Hasselblatt, M., Thomas, C., Korshunov, A., Rhizova, M., Wittmann, A., Kaufhold, A., Iskar, M., Ketteler, P., Lohmann, D., Orr, B. A., Ellison, D. W., von Hoff, K., Mynarek, M., Rutkowski, S., Sahm, F., von Deimling, A., Lichter, P., Kool, M., Zapatka, M., Pfister, S. M. & Jones, D. T. W., 02.2020, In: ACTA NEUROPATHOL. 139, 2, p. 243-257 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  346. Social inequalities in the participation and activity of children and adolescents with leukemia, brain tumors, and sarcomas (SUPATEEN): a protocol for a multicenter longitudinal prospective observational study

    Roick, J., Berner, R., Bernig, T., Erdlenbruch, B., Escherich, G., Faber, J., Klein, C., Bochennek, K., Kratz, C., Kühr, J., Längler, A., Lode, H. N., Metzler, M., Müller, H., Reinhardt, D., Sauerbrey, A., Schepper, F., Scheurlen, W., Schneider, D., Schwabe, G. C. & Richter, M., 31.01.2020, In: BMC PEDIATR. 20, 1, p. 48

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  347. Evidence for the Misfolding of the A1 Domain within Multimeric von Willebrand Factor in Type 2 von Willebrand Disease

    Tischer, A., Brehm, M. A., Machha, V. R., Moon-Tasson, L., Benson, L. M., Nelton, K. J., Leger, R. R., Obser, T., Martinez-Vargas, M., Whitten, S. T., Chen, D., Pruthi, R. K., Bergen, H. R., Cruz, M. A., Schneppenheim, R. & Auton, M., 17.01.2020, In: J MOL BIOL. 432, 2, p. 305-323 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  348. Ulceration in Prolidase Deficiency: Successful Treatment with Anticoagulants

    Süßmuth, K., Metze, D., Muresan, A-M., Lehmberg, K., Zur Stadt, U., Speckmann, C., Park, J. H., Marquardt, T., Oji, V. & Goerge, T., 07.01.2020, In: ACTA DERM-VENEREOL. 100, 1, p. adv00002

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  349. Comprehensive assessments and related interventions to enhance the long-term outcomes of child, adolescent and young adult cancer survivors - presentation of the CARE for CAYA-Program study protocol and associated literature review

    Salchow, J., Mann, J., Koch, B., von Grundherr, J., Jensen, W., Elmers, S., Straub, L. A., Vettorazzi, E., Escherich, G., Rutkowski, S., Dwinger, S., Bergelt, C., Sokalska-Duhme, M., Bielack, S., Calaminus, G., Baust, K., Classen, C. F., Rössig, C., Faber, J., Faller, H., Hilgendorf, I., Gebauer, J., Langer, T., Metzler, M., Schuster, S., Niemeyer, C., Puzik, A., Reinhardt, D., Dirksen, U., Sander, A., Köhler, M., Habermann, J. K., Bokemeyer, C. & Stein, A., 06.01.2020, In: BMC CANCER. 20, 1, p. 16

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  350. Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma

    Begemann, M., Waszak, S. M., Robinson, G. W., Jäger, N., Sharma, T., Knopp, C., Kraft, F., Moser, O., Mynarek, M., Guerrini-Rousseau, L., Brugieres, L., Varlet, P., Pietsch, T., Bowers, D. C., Chintagumpala, M., Sahm, F., Korbel, J. O., Rutkowski, S., Eggermann, T., Gajjar, A., Northcott, P., Elbracht, M., Pfister, S. M., Kontny, U. & Kurth, I., 01.01.2020, In: J CLIN ONCOL. 38, 1, p. 43-50 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  351. Acute impact of an endurance race on cardiac function and biomarkers of myocardial injury in triathletes with and without myocardial fibrosis

    Tahir, E., Scherz, B., Starekova, J., Muellerleile, K., Fischer, R., Schoennagel, B., Warncke, M., Stehning, C., Cavus, E., Bohnen, S., Radunski, U. K., Blankenberg, S., Simon, P., Pressler, A., Adam, G., Patten, M. & Lund, G. K., 01.2020, In: EUR J PREV CARDIOL. 27, 1, p. 94-104 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  352. Distinct molecular response patterns of activating STAT3 mutations associate with penetrance of lymphoproliferation and autoimmunity

    Jägle, S., Heeg, M., Grün, S., Rensing-Ehl, A., Maccari, M. E., Klemann, C., Jones, N., Lehmberg, K., Bettoni, C., Warnatz, K., Grimbacher, B., Biebl, A., Schauer, U., Hague, R., Neth, O., Mauracher, A., Pachlopnik Schmid, J., Fabre, A., Kostyuchenko, L., Führer, M., Lorenz, M. R., Schwarz, K., Rohr, J. & Ehl, S., 01.2020, In: CLIN IMMUNOL. 210, p. 108316

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  353. Functional flow cytometry of monocytes for routine diagnosis of innate primary immunodeficiencies

    Ammann, S., Fuchs, S., Martin-Martin, L., Castro, C. N., Spielberger, B., Klemann, C., Elling, R., Heeg, M., Speckmann, C., Hainmann, I., Kaiser-Labusch, P., Horneff, G., Thalhammer, J., Bredius, R. G., Stadt, U. Z., Lehmberg, K., Fuchs, I., von Spee-Mayer, C., Henneke, P. & Ehl, S., 01.2020, In: J ALLERGY CLIN IMMUN. 145, 1, p. 434-437.e4

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  354. Spinal cord atypical teratoid/rhabdoid tumors in children: Clinical, genetic, and outcome characteristics in a representative European cohort

    Benesch, M., Nemes, K., Neumayer, P., Hasselblatt, M., Timmermann, B., Bison, B., Ebetsberger-Dachs, G., Bourdeaut, F., Dufour, C., Biassoni, V., Morales La Madrid, A., Entz-Werle, N., Laithier, V., Quehenberger, F., Weis, S., Sumerauer, D., Siebert, R., Bens, S., Schneppenheim, R., Kool, M., Modena, P., Fouyssac, F. & C Frühwald, M., 01.2020, In: PEDIATR BLOOD CANCER. 67, 1, p. e28022

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  355. Cell Versus Cytokine - Directed Therapies for Hemophagocytic Lymphohistiocytosis (HLH) in Inborn Errors of Immunity

    Wegehaupt, O., Wustrau, K., Lehmberg, K. & Ehl, S., 2020, In: FRONT IMMUNOL. 11, 808.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  356. Interpretable Deep Neural Network to Predict Estrogen Receptor Status from Haematoxylin-Eosin Images

    Seegerer, P., Binder, A., Saitenmacher, R., Bockmayr, M., Alber, M., Jurmeister, P., Klauschen, F. & Müller, K. R., 2020, Artificial Intelligence and Machine Learning for Digital Pathology. Holzinger, A., Goebel, R., Mengel, M. & Müller, H. (eds.). 1 ed. Cham: Springer Heidelberg, p. 16-37 22 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 12090 LNCS).

    Research output: SCORING: Contribution to book/anthologyChapterResearchpeer-review

  357. Parents' perception of their children's process of reintegration after childhood cancer treatment

    Inhestern, L., Peikert, M. L., Krauth, K. A., Escherich, G., Rutkowski, S., Kandels, D. & Bergelt, C., 2020, In: PLOS ONE. 15, 10, p. e0239967

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  358. Quantification of minimal disseminated disease by quantitative PCR and digital PCR for NPM-ALK as prognostic factor in children with anaplastic large cell lymphoma

    Damm-Welk, C., Kutscher, N., Zimmermann, M., Attarbaschi, A., Schieferstein, J., Knörr, F., Oschlies, I., Klapper, W. & Woessmann, W., 2020, In: HAEMATOLOGICA. 105, 8, p. 2141-2149

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  359. Treatment of children under 4 years of age with medulloblastoma and ependymoma in the HIT2000/HIT-REZ 2005 trials: Neuropsychological outcome 5 years after treatment

    Ottensmeier, H., Schlegel, P. G., Eyrich, M., Wolff, J. E., Juhnke, B-O., von Hoff, K., Frahsek, S., Schmidt, R., Faldum, A., Fleischhack, G., von Bueren, A., Friedrich, C., Resch, A., Warmuth-Metz, M., Krauss, J., Kortmann, R. D., Bode, U., Kühl, J. & Rutkowski, S., 2020, In: PLOS ONE. 15, 1, p. e0227693

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  360. Tuberculosis-Associated HLH in an 8-Month-Old Infant: A Case Report and Review

    Hauch, H., Skrzypek, S., Woessmann, W., Lehmberg, K., Ehl, S., Speckmann, C., Schneck, E., Koerholz, D., Jux, C. & Neuhäuser, C., 2020, In: FRONT PEDIATR. 8, 556155.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  361. Upshaw-Schulman syndrome-associated ADAMTS13 variants possess proteolytic activity at the surface of endothelial cells and in simulated circulation

    Letzer, A., Lehmann, K., Mess, C., König, G., Obser, T., Peine, S., Schneppenheim, S., Budde, U., Schneider, S. W., Schneppenheim, R. & Brehm, M. A., 2020, In: PLOS ONE. 15, 5, p. e0232637

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  362. Using the SNAP-Tag technology to easily measure and demonstrate apoptotic changes in cancer and blood cells with different dyes

    Woitok, M., Grieger, E., Akinrinmade, O. A., Bethke, S., Pham, A. T., Stein, C., Fendel, R., Fischer, R., Barth, S. & Niesen, J., 2020, In: PLOS ONE. 15, 12, p. e0243286

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  363. 2019
  364. Primary central nervous system lymphoma: initial features, outcome, and late effects in 75 children and adolescents

    Attarbaschi, A., Abla, O., Ronceray, L., Bansil, S., Bomken, S., Burkhardt, B., Ceppi, F., Chiang, A. K. S., Dave, H., Fedorova, A., Henry, M., Jazbec, J., Kabickova, E., Kotecha, R. S., Lazic, J., Loeffen, J., Miakova, N., Osumi, T., Pillon, M., Pourtsidis, A., Rigaud, C., Tamamyan, G., Tandon, S., Uyttebroeck, A., Verdu-Amoros, J., Woessmann, W., Wrobel, G., Giulino-Roth, L., European Intergrp Childhood Non-Ho, Int Berlin-Frankfurt-Munster Study & Selected North Amer Ctr Pediat Hem, 23.12.2019, In: Blood Adv. 3, 24, p. 4291-4297 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  365. Improving Stratification for Children With Late Bone Marrow B-Cell Acute Lymphoblastic Leukemia Relapses With Refined Response Classification and Integration of Genetics

    Eckert, C., Groeneveld-Krentz, S., Kirschner-Schwabe, R., Hagedorn, N., Chen-Santel, C., Bader, P., Borkhardt, A., Cario, G., Escherich, G., Panzer-Grümayer, R., Astrahantseff, K., Eggert, A., Sramkova, L., Attarbaschi, A., Bourquin, J-P., Peters, C., Henze, G., von Stackelberg, A. & ALL-REZ BFM Trial Group, 20.12.2019, In: J CLIN ONCOL. 37, 36, p. 3493-3506 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  366. MRI Phenotype of RELA-fused Pediatric Supratentorial Ependymoma

    Nowak, J., Jünger, S. T., Huflage, H., Seidel, C., Hohm, A., Vandergrift, L. A., von Hoff, K., Rutkowski, S., Pietsch, T. & Warmuth-Metz, M., 19.12.2019, In: CLIN NEURORADIOL. 29, 4, p. 595-604 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  367. Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia

    van Tilburg, C. M., Milde, T., Witt, R., Ecker, J., Hielscher, T., Seitz, A., Schenk, J-P., Buhl, J. L., Riehl, D., Frühwald, M. C., Pekrun, A., Rossig, C., Wieland, R., Flotho, C., Kordes, U., Gruhn, B., Simon, T., Linderkamp, C., Sahm, F., Taylor, L., Freitag, A., Burhenne, J., Foerster, K. I., Meid, A. D., Pfister, S. M., Karapanagiotou-Schenkel, I. & Witt, O., 10.12.2019, In: CLIN EPIGENETICS. 11, 1, p. 188

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  368. The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration

    Schoof, M., Launspach, M., Holdhof, D., Nguyen, L., Engel, V., Filser, S., Peters, F., Immenschuh, J., Hellwig, M., Niesen, J., Mall, V., Ertl-Wagner, B., Hagel, C., Spohn, M., Lutz, B., Sedlacik, J., Indenbirken, D., Merk, D. J. & Schüller, U., 05.12.2019, In: ACTA NEUROPATHOL COM. 7, 1, p. 199

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  369. The molecular landscape of ETMR at diagnosis and relapse

    Lambo, S., Gröbner, S. N., Rausch, T., Waszak, S. M., Schmidt, C., Gorthi, A., Romero, J. C., Mauermann, M., Brabetz, S., Krausert, S., Buchhalter, I., Koster, J., Zwijnenburg, D. A., Sill, M., Hübner, J-M., Mack, N., Schwalm, B., Ryzhova, M., Hovestadt, V., Papillon-Cavanagh, S., Chan, J. A., Landgraf, P., Ho, B., Milde, T., Witt, O., Ecker, J., Sahm, F., Sumerauer, D., Ellison, D. W., Orr, B. A., Darabi, A., Haberler, C., Figarella-Branger, D., Wesseling, P., Schittenhelm, J., Remke, M., Taylor, M. D., Gil-da-Costa, M. J., Łastowska, M., Grajkowska, W., Hasselblatt, M., Hauser, P., Pietsch, T., Uro-Coste, E., Bourdeaut, F., Masliah-Planchon, J., Rigau, V., Alexandrescu, S., Wolf, S., Li, X-N., Schüller, U., Snuderl, M., Karajannis, M. A., Giangaspero, F., Jabado, N., von Deimling, A., Jones, D. T. W., Korbel, J. O., von Hoff, K., Lichter, P., Huang, A., Bishop, A. J. R., Pfister, S. M., Korshunov, A. & Kool, M., 12.2019, In: NATURE. 576, 7786, p. 274-280 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  370. Zinkmangel als Ursache eines „Dekubitus“ beim Frühgeborenen?

    Asselborn, J. R., Thayssen, M., Lehmberg, K., Apostolidou, S. & Singer, D., 12.2019, In: Z GEBURTSH NEONATOL. 223, 6, p. 369-372 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  371. Characterization of novel, recurrent genomic rearrangements as sensitive MRD targets in childhood B-cell precursor ALL

    Zur Stadt, U., Alawi, M., Adao, M., Indenbirken, D., Escherich, G. & Horstmann, M. A., 29.11.2019, In: BLOOD CANCER J. 9, 12, p. 96

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  372. Results of CoALL 07-03 study childhood ALL based on combined risk assessment by in vivo and in vitro pharmacosensitivity

    Schramm, F., Zur Stadt, U., Zimmermann, M., Jorch, N., Pekrun, A., Borkhardt, A., Imschweiler, T., Christiansen, H., Faber, J., Schmid, I., Feuchtinger, T., Beron, G., den Boer, M. L., Pieters, R., Horstmann, M. A., Janka-Schaub, G. E. & Escherich, G., 26.11.2019, In: Blood Adv. 3, 22, p. 3688-3699 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  373. Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features - a retrospective analysis of the HIT ependymoma trial cohort

    Jünger, S. T., Mynarek, M., Wohlers, I., Dörner, E., Mühlen, A. Z., Velez-Char, N., von Hoff, K., Rutkowski, S., Warmuth-Metz, M., Kortmann, R-D., Timmermann, B., Rahmann, S., Klein-Hitpass, L., von Bueren, A. O. & Pietsch, T., 14.11.2019, In: ACTA NEUROPATHOL COM. 7, 1, p. 181

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  374. Comparison of procalcitonin and C-reactive protein as early diagnostic marker for the identification of transplant-related adverse events after allogeneic hematopoietic stem cell transplantation in pediatric patients

    Cabanillas Stanchi, K. M., Queudeville, M., Malaval, C., Feucht, J., Schlegel, P., Dobratz, M., Seitz, C., Müller, I., Lang, P., Handgretinger, R. & Döring, M., 11.2019, In: J CANCER RES CLIN. 145, 11, p. 2779-2791 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  375. Identification of Distant Metastases From Recurrent Gliosarcoma Using Whole-Body 18F-FDG PET/CT

    Unterrainer, M., Ruf, V., Cyran, C. C., Brendel, M., Thon, N., Herms, J., Schüller, U., Tonn, J-C., Bartenstein, P. & Albert, N. L., 11.2019, In: CLIN NUCL MED. 44, 11, p. 923-924 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  376. Imaging Characteristics of Wingless Pathway Subgroup Medulloblastomas: Results from the German HIT/SIOP-Trial Cohort

    Stock, A., Mynarek, M., Pietsch, T., Pfister, S. M., Clifford, S. C., Goschzik, T., Sturm, D., Schwalbe, E. C., Hicks, D., Rutkowski, S., Bison, B., Pham, M. & Warmuth-Metz, M., 11.2019, In: AM J NEURORADIOL. 40, 11, p. 1811-1817 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  377. Presence of centromeric but absence of telomeric group B KIR haplotypes in stem cell donors improve leukaemia control after HSCT for childhood ALL

    Babor, F., Peters, C., Manser, A. R., Glogova, E., Sauer, M., Pötschger, U., Ahlmann, M., Cario, G., Feuchtinger, T., Gruhn, B., Güngör, T., Kremens, B., Lang, P., Mezger, M., Müller, I., Mytilineos, J., Oevermann, L., Pichler, H., Scherenschlich, N., Schuster, F. R., Siepermann, M., Stachel, D., Strahm, B., Wössmann, W., Escherich, G., Zimmermann, M., Schrappe, M., Borkhardt, A., Eckert, C., Bader, P., Uhrberg, M. & Meisel, R., 11.2019, In: BONE MARROW TRANSPL. 54, 11, p. 1847-1858 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  378. The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia

    Velthaus, A., Cornils, K., Hennigs, J. K., Grüb, S., Stamm, H., Wicklein, D., Bokemeyer, C., Heuser, M., Windhorst, S., Fiedler, W. & Wellbrock, J., 26.10.2019, In: CANCERS. 11, 11

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  379. An in-depth multi-omics analysis in RLE-6TN rat alveolar epithelial cells allows for nanomaterial categorization

    Karkossa, I., Bannuscher, A., Hellack, B., Bahl, A., Buhs, S., Nollau, P., Luch, A., Schubert, K., von Bergen, M. & Haase, A., 25.10.2019, In: PART FIBRE TOXICOL. 16, 1, p. 38

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  380. Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets

    Hoell, J. I., Ginzel, S., Kuhlen, M., Kloetgen, A., Gombert, M., Fischer, U., Hein, D., Demir, S., Stanulla, M., Schrappe, M., Zur Stadt, U., Bader, P., Babor, F., Schuster, F., Strahm, B., Alten, J., Moericke, A., Escherich, G., von Stackelberg, A., Thiele, R., McHardy, A. C., Peters, C., Bornhauser, B., Bourquin, J-P., Krause, S., Enczmann, J., Meyer, L. H., Eckert, C., Borkhardt, A. & Meisel, R., 22.10.2019, In: Blood Adv. 3, 20, p. 3143-3156 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  381. Allogeneic hematopoietic stem cell transplantation in two brothers with DNA ligase IV deficiency -a case report and review of the literature

    Schober, S., Schilbach, K., Doering, M., Cabanillas Stanchi, K. M., Holzer, U., Kasteleiner, P., Schittenhelm, J., Schaefer, J. F., Müller, I., Lang, P. & Handgretinger, R., 11.10.2019, In: BMC PEDIATR. 19, 1, p. 346

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  382. NUTM1 is a recurrent fusion gene partner in B cell precursor acute lymphoblastic leukemia associated with increased expression of genes on chromosome band 10p12.31-12.2

    Hormann, F. M., Hoogkamer, A. Q., Beverloo, H. B., Boeree, A., Dingjan, I., Wattel, M. M., Stam, R. W., Escherich, G., Pieters, R., den Boer, M. L. & Boer, J. M., 10.2019, In: HAEMATOLOGICA. 104, 10, p. e455-e459

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  383. The International Hereditary Thrombotic Thrombocytopenic Purpura Registry: key findings at enrollment until 2017

    van Dorland, H. A., Taleghani, M. M., Sakai, K., Friedman, K. D., George, J. N., Hrachovinova, I., Knöbl, P. N., von Krogh, A. S., Schneppenheim, R., Aebi-Huber, I., Bütikofer, L., Largiadèr, C. R., Cermakova, Z., Kokame, K., Miyata, T., Yagi, H., Terrell, D. R., Vesely, S. K., Matsumoto, M., Lämmle, B., Fujimura, Y., Kremer Hovinga, J. A. & Hereditary TTP Registry, 10.2019, In: HAEMATOLOGICA. 104, 10, p. 2107-2115 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  384. Analyzing expression and phosphorylation of the EGF receptor in HNSCC

    Kriegs, M., Clauditz, T. S., Hoffer, K., Bartels, J., Buhs, S., Gerull, H., Zech, H. B., Bußmann, L., Struve, N., Rieckmann, T., Petersen, C., Betz, C. S., Rothkamm, K., Nollau, P. & Münscher, A., 19.09.2019, In: SCI REP-UK. 9, 1, p. 13564

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  385. Multiplexed protein force spectroscopy reveals equilibrium protein folding dynamics and the low-force response of von Willebrand factor

    Löf, A., Walker, P. U., Sedlak, S. M., Gruber, S., Obser, T., Brehm, M. A., Benoit, M. & Lipfert, J., 17.09.2019, In: P NATL ACAD SCI USA. 116, 38, p. 18798-18807 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  386. Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases

    Jurmeister, P., Bockmayr, M., Seegerer, P., Bockmayr, T., Treue, D., Montavon, G., Vollbrecht, C., Arnold, A., Teichmann, D., Bressem, K., Schüller, U., von Laffert, M., Müller, K-R., Capper, D. & Klauschen, F., 11.09.2019, In: SCI TRANSL MED. 11, 509

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  387. Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study

    Pieters, R., De Lorenzo, P., Ancliffe, P., Aversa, L. A., Brethon, B., Biondi, A., Campbell, M., Escherich, G., Ferster, A., Gardner, R. A., Kotecha, R. S., Lausen, B., Li, C. K., Locatelli, F., Attarbaschi, A., Peters, C., Rubnitz, J. E., Silverman, L. B., Stary, J., Szczepanski, T., Vora, A., Schrappe, M. & Valsecchi, M. G., 01.09.2019, In: J CLIN ONCOL. 37, 25, p. 2246-2256 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  388. Effect of renal denervation procedure on left ventricular mass, myocardial strain and diastolic function by CMR on a 12-month follow-up

    Tahir, E., Koops, A., Warncke, M. L., Starekova, J., Neumann, J. T., Waldeyer, C., Avanesov, M., Lund, G. K., Fischer, R., Adam, G., Blankenberg, S., Wenzel, U. O. & Brunner, F. J., 09.2019, In: JPN J RADIOL. 37, 9, p. 642-650 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  389. Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL-USP2 fusions

    Meyer, C., Lopes, B. A., Caye-Eude, A., Cavé, H., Arfeuille, C., Cuccuini, W., Sutton, R., Venn, N. C., Oh, S. H., Tsaur, G., Escherich, G., Feuchtinger, T., Kosasih, H. J., Khaw, S. L., Ekert, P. G., Pombo-de-Oliveira, M. S., Bidet, A., Djahanschiri, B., Ebersberger, I., Zaliova, M., Zuna, J., Zermanova, Z., Juvonen, V., Grümayer, R. P., Fazio, G., Cazzaniga, G., Larghero, P., Emerenciano, M. & Marschalek, R., 09.2019, In: LEUKEMIA. 33, 9, p. 2306-2340 35 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  390. Immunologic Profiling of Mutational and Transcriptional Subgroups in Pediatric and Adult High-Grade Gliomas

    Bockmayr, M., Klauschen, F., Maire, C. L., Rutkowski, S., Westphal, M., Lamszus, K., Schüller, U. & Mohme, M., 09.2019, In: CANCER IMMUNOL RES. 7, 9, p. 1401-1411 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  391. Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series

    Benesch, M., Mynarek, M., Witt, H., Warmuth-Metz, M., Pietsch, T., Bison, B., Pfister, S. M., Pajtler, K. W., Kool, M., Schüller, U., Pietschmann, K., Juhnke, B-O., Tippelt, S., Fleischhack, G., Schmid, I., Kramm, C. M., Vorwerk, P., Beilken, A., Classen, C. F., Hernáiz Driever, P., Kropshofer, G., Imschweiler, T., Lemmer, A., Kortmann, R-D., Rutkowski, S. & von Hoff, K., 09.2019, In: ONCOLOGIST. 24, 9, p. e921-e929

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  392. Immature O-glycans recognized by the macrophage glycoreceptor CLEC10A (MGL) are induced by 4-hydroxy-tamoxifen, oxidative stress and DNA-damage in breast cancer cells

    Kurze, A-K., Buhs, S., Eggert, D., Oliveira-Ferrer, L., Müller, V., Niendorf, A., Wagener, C. & Nollau, P., 27.08.2019, In: CELL COMMUN SIGNAL. 17, 1, p. 107

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  393. Pegvaliase: Immunological profile and recommendations for the clinical management of hypersensitivity reactions in patients with phenylketonuria treated with this enzyme substitution therapy

    Hausmann, O., Daha, M., Longo, N., Knol, E., Müller, I., Northrup, H. & Brockow, K., 04.08.2019, In: MOL GENET METAB. 128, 1-2, p. 84-91 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  394. Allogeneic hematopoietic stem cell transplantation from unrelated donors is associated with higher infection rates in children with acute lymphoblastic leukemia-A prospective international multicenter trial on behalf of the BFM-SG and the EBMT-PDWP

    Pichler, H., Lawitschka, A., Glogova, E., Willasch, A. M., von Luettichau, I., Lehrnbecher, T., Matthes-Martin, S., Lang, P., Bader, P., Sykora, K. W., Schrum, J., Kremens, B., Ehlert, K., Albert, M. H., Kuhlen, M., Meisel, R., Guengoer, T., Strahm, B., Gruhn, B., Schulz, A., Woessmann, W., Poetschger, U. & Peters, C., 08.2019, In: AM J HEMATOL. 94, 8, p. 880-890 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  395. High sensitivity and clonal stability of the genomic fusion as single marker for response monitoring in ETV6-RUNX1-positive acute lymphoblastic leukemia

    Hoffmann, J., Krumbholz, M., Gutiérrez, H. P., Fillies, M., Szymansky, A., Bleckmann, K., Zur Stadt, U., Köhler, R., Kuiper, R. P., Horstmann, M., von Stackelberg, A., Eckert, C. & Metzler, M., 08.2019, In: PEDIATR BLOOD CANCER. 66, 8, p. e27780

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  396. Immunhistochemische Analyse von Bcl-2, nukleärem S100A4, MITF und Ki67 zur Risikostratifizierung von Melanomen im Frühstadium - ein kombinierter immunhistochemischer Score

    Jurmeister, P., Bockmayr, M., Treese, C., Stein, U., Lenze, D., Jöhrens, K., Friedling, F., Dietel, M., Klauschen, F., Marsch, W., Fiedler, E. & von Laffert, M., 08.2019, In: J DTSCH DERMATOL GES. 17, 8, p. 800-809 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  397. Immunohistochemical analysis of Bcl-2, nuclear S100A4, MITF and Ki67 for risk stratification of early-stage melanoma - A combined IHC score for melanoma risk stratification

    Jurmeister, P., Bockmayr, M., Treese, C., Stein, U., Lenze, D., Jöhrens, K., Friedling, F., Dietel, M., Klauschen, F., Marsch, W., Fiedler, E. & von Laffert, M., 08.2019, In: J DTSCH DERMATOL GES. 17, 8, p. 800-808 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  398. PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia

    Bastian, L., Schroeder, M. P., Eckert, C., Schlee, C., Tanchez, J. O., Kämpf, S., Wagner, D. L., Schulze, V., Isaakidis, K., Lázaro-Navarro, J., Hänzelmann, S., James, A. R., Ekici, A., Burmeister, T., Schwartz, S., Schrappe, M., Horstmann, M., Vosberg, S., Krebs, S., Blum, H., Hecht, J., Greif, P. A., Rieger, M. A., Brüggemann, M., Gökbuget, N., Neumann, M. & Baldus, C. D., 08.2019, In: LEUKEMIA. 33, 8, p. 1895-1909 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  399. Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes

    Sharma, T., Schwalbe, E. C., Williamson, D., Sill, M., Hovestadt, V., Mynarek, M., Rutkowski, S., Robinson, G. W., Gajjar, A., Cavalli, F., Ramaswamy, V., Taylor, M. D., Lindsey, J. C., Hill, R. M., Jäger, N., Korshunov, A., Hicks, D., Bailey, S., Kool, M., Chavez, L., Northcott, P. A., Pfister, S. M. & Clifford, S. C., 08.2019, In: ACTA NEUROPATHOL. 138, 2, p. 309-326 18 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  400. Food authentication: Multi-elemental analysis of white asparagus for provenance discrimination

    Richter, B., Gurk, S., Wagner, D., Bockmayr, M. & Fischer, M., 15.07.2019, In: FOOD CHEM. 286, p. 475-482

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  401. Alteration in GPIIb/IIIa Binding of VWD-Associated von Willebrand Factor Variants with C-Terminal Missense Mutations

    König, G., Obser, T., Marggraf, O., Schneppenheim, S., Budde, U., Schneppenheim, R. & Brehm, M. A., 07.2019, In: THROMB HAEMOSTASIS. 119, 7, p. 1102-1111 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  402. Clostridium difficile infection after pediatric solid organ transplantation: a practical single-center experience

    Breuer, C., Döring, S., Rohde, H., Rutkowski, S., Müller, I. & Oh, J., 07.2019, In: PEDIATR NEPHROL. 34, 7, p. 1269-1275 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  403. Comparison of Immune Reconstitution After Allogeneic Versus Autologous Stem Cell Transplantation in 182 Pediatric Recipients

    Wiegering, V., Eyrich, M., Winkler, B. & Schlegel, P. G., 07.2019, In: J PEDIAT HEMATOL ONC. 41, 5, p. e302-e307

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  404. Recommendations for the management of hemophagocytic lymphohistiocytosis in adults

    La Rosée, P., Horne, A., Hines, M., von Bahr Greenwood, T., Machowicz, R., Berliner, N., Birndt, S., Gil-Herrera, J., Girschikofsky, M., Jordan, M. B., Kumar, A., van Laar, J. A. M., Lachmann, G., Nichols, K. E., Ramanan, A. V., Wang, Y., Wang, Z., Janka, G. & Henter, J-I., 06.06.2019, In: BLOOD. 133, 23, p. 2465-2477 13 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  405. Rare mature B-cell lymphomas in children and adolescents

    Woessmann, W. & Quintanilla-Martinez, L., 06.2019, In: HEMATOL ONCOL. 37 Suppl 1, p. 53-61 9 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  406. Relapse of a group 4 medulloblastoma after 18 years as proven by histology and DNA methylation profiling

    Ricklefs, F. L., Fritzsche, F., Winkler, B., Meissner, B., Dührsen, L., Westphal, M., Rutkowski, S., Martens, T. & Schüller, U., 06.2019, In: CHILD NERV SYST. 35, 6, p. 1029-1033 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  407. The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection

    Miarka, L., Hauser, C., Helm, O., Holdhof, D., Beckinger, S., Egberts, J-H., Gundlach, J-P., Lenk, L., Rahn, S., Mikulits, W., Trauzold, A. & Sebens, S., 29.05.2019, In: CANCERS. 11, 6

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  408. EZH2 Inhibition in Ewing Sarcoma Upregulates G Expression for Targeting with Gene-Modified T Cells

    Kailayangiri, S., Altvater, B., Lesch, S., Balbach, S., Göttlich, C., Kühnemundt, J., Mikesch, J-H., Schelhaas, S., Jamitzky, S., Meltzer, J., Farwick, N., Greune, L., Fluegge, M., Kerl, K., Lode, H. N., Siebert, N., Müller, I., Walles, H., Hartmann, W. & Rossig, C., 08.05.2019, In: MOL THER. 27, 5, p. 933-946 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  409. Targeting APLN/APLNR improves anti-angiogenic efficiency and blunts pro-invasive side effects of VEGFA/VEGFR2-blockade in glioblastoma

    Mastrella, G., Hou, M., Li, M., Stoecklein, V. M., Zdouc, N., Volmar, M. N. M., Miletic, H., Reinhard, S., Herold-Mende, C. C., Kleber, S., Eisenhut, K., Gargiulo, G., Synowitz, M., Vescovi, A. L., Harter, P. N., Penninger, J. M., Wagner, E., Mittelbronn, M., Bjerkvig, R., Hambardzumyan, D., Schüller, U., Tonn, J-C., Radke, J., Glass, R. & Kälin, R. E., 01.05.2019, In: CANCER RES. 79, 9, p. 2298-2313 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  410. IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia

    Lopes, B. A., Meyer, C., Barbosa, T. C., Poubel, C. P., Mansur, M. B., Duployez, N., Bashton, M., Harrison, C. J., Zur Stadt, U., Horstmann, M., Pombo-de-Oliveira, M. S., Palmi, C., Cazzaniga, G., Venn, N. C., Sutton, R., Alonso, C. N., Tsaur, G., Gupta, S. K., Bakhshi, S., Marschalek, R. & Emerenciano, M., 05.2019, In: TRANSL ONCOL. 12, 5, p. 726-732 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  411. Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair

    Seoane, M., Buhs, S., Iglesias, P., Strauss, J., Puller, A-C., Müller, J., Gerull, H., Feldhaus, S., Alawi, M., Brandner, J. M., Eggert, D., Du, J., Thomale, J., Wild, P. J., Zimmermann, M., Sternsdorf, T., Schumacher, U., Nollau, P., Fisher, D. E. & Horstmann, M. A., 05.2019, In: ONCOGENE. 38, 19, p. 3616-3635 20 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  412. New options of cancer treatment employing InsP6

    Brehm, M. A. & Windhorst, S., 05.2019, In: BIOCHEM PHARMACOL. 163, p. 206-214 9 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  413. Nimotuzumab and radiotherapy for treatment of newly diagnosed diffuse intrinsic pontine glioma (DIPG): a phase III clinical study

    Fleischhack, G., Massimino, M., Warmuth-Metz, M., Khuhlaeva, E., Janssen, G., Graf, N., Rutkowski, S., Beilken, A., Schmid, I., Biassoni, V., Gorelishev, S. K., Kramm, C., Reinhard, H., Schlegel, P. G., Kortmann, R-D., Reuter, D., Bach, F., Iznaga-Escobar, N. E. & Bode, U., 05.2019, In: J NEURO-ONCOL. 143, 1, p. 107-113 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  414. Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA

    Hou, Y., Pinheiro, J., Sahm, F., Reuss, D. E., Schrimpf, D., Stichel, D., Casalini, B., Koelsche, C., Sievers, P., Wefers, A. K., Reinhardt, A., Ebrahimi, A., Fernández-Klett, F., Pusch, S., Meier, J., Schweizer, L., Paulus, W., Prinz, M., Hartmann, C., Plate, K. H., Reifenberger, G., Pietsch, T., Varlet, P., Pagès, M., Schüller, U., Scheie, D., de Stricker, K., Frank, S., Hench, J., Pollo, B., Brandner, S., Unterberg, A., Pfister, S. M., Jones, D. T. W., Korshunov, A., Wick, W., Capper, D., Blümcke, I., von Deimling, A. & Bertero, L., 05.2019, In: ACTA NEUROPATHOL. 137, 5, p. 837-846 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  415. Predictive factors associated with ventriculoperitoneal shunting after posterior fossa tumor surgery in children

    Helmbold, L. J., Kammler, G., Regelsberger, J., Fritzsche, F. S., Emami, P., Schüller, U. & Krajewski, K., 05.2019, In: CHILD NERV SYST. 35, 5, p. 779-788 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  416. Two molecularly distinct atypical teratoid/rhabdoid tumors (or tumor components) occurring in an infant with rhabdoid tumor predisposition syndrome 1

    Thomas, C., Knerlich-Lukoschus, F., Reinhard, H., Johann, P. D., Sturm, D., Sahm, F., Bens, S., Vogt, J., Nemes, K., Oyen, F., Kordes, U., Siebert, R., Schneppenheim, R., Messing-Jünger, M., Pietsch, T., von Deimling, A., Paulus, W., Pfister, S. M., Kool, M., Frühwald, M. C. & Hasselblatt, M., 05.2019, In: ACTA NEUROPATHOL. 137, 5, p. 847-850 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  417. Nanobody-targeting of epidermal growth factor receptor (EGFR) ectodomain variants overcomes resistance to therapeutic EGFR antibodies

    Tintelnot, J., Baum, N., Schultheiss, C., Braig, F., Trentmann, M., Finter, J., Fumey, W., Bannas, P., Fehse, B., Riecken, K., Schütze, K., Bokemeyer, C., Rösner, T., Valerius, T., Peipp, M., Koch-Nolte, F. & Binder, M., 04.2019, In: MOL CANCER THER. 18, 4, p. 823-833 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  418. TCF4 (E2-2) harbors tumor suppressive functions in SHH medulloblastoma

    Hellwig, M., Lauffer, M. C., Bockmayr, M., Spohn, M., Merk, D. J., Harrison, L., Ahlfeld, J., Kitowski, A., Neumann, J. E., Ohli, J., Holdhof, D., Niesen, J., Schoof, M., Kool, M., Kraus, C., Zweier, C., Holmberg, D. & Schüller, U., 04.2019, In: ACTA NEUROPATHOL. 137, 4, p. 657-673 17 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  419. A multicenter study of patients with multisystem Langerhans cell histiocytosis who develop secondary hemophagocytic lymphohistiocytosis

    Chellapandian, D., Hines, M. R., Zhang, R., Jeng, M., van den Bos, C., Santa-María López, V., Lehmberg, K., Sieni, E., Wang, Y., Nakano, T., Williams, J. A., Fustino, N. J., Astigarraga, I., Dunkel, I. J., Abla, O., van Halteren, A. G. S., Pei, D., Cheng, C., Weitzman, S., Sung, L. & Nichols, K. E., 15.03.2019, In: CANCER-AM CANCER SOC. 125, 6, p. 963-971 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  420. Copy number alterations in B-cell development genes, drug resistance, and clinical outcome in pediatric B-cell precursor acute lymphoblastic leukemia

    Steeghs, E. M. P., Boer, J. M., Hoogkamer, A. Q., Boeree, A., de Haas, V., de Groot-Kruseman, H. A., Horstmann, M. A., Escherich, G., Pieters, R. & den Boer, M. L., 15.03.2019, In: SCI REP-UK. 9, 1, p. 4634

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  421. CD38 is not expressed in pediatric ALK-positive anaplastic large cell lymphoma

    Au-Yeung, R. K. H., Burkhardt, B., Woessmann, W. & Klapper, W., 03.2019, In: PEDIATR BLOOD CANCER. 66, 3, p. e27541

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  422. Characterization of VWF gene conversions causing von Willebrand disease

    Ahmad, F., Kannan, M., Obser, T., Budde, U., Schneppenheim, S., Saxena, R. & Schneppenheim, R., 03.2019, In: BRIT J HAEMATOL. 184, 5, p. 817-825 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  423. Hematopoietic Stem Cell Transplantation as Treatment for Patients with DOCK8 Deficiency

    Aydin, S. E., Freeman, A. F., Al-Herz, W., Al-Mousa, H. A., Arnaout, R. K., Aydin, R. C., Barlogis, V., Belohradsky, B. H., Bonfim, C., Bredius, R. G., Chu, J. I., Ciocarlie, O. C., Doğu, F., Gaspar, H. B., Geha, R. S., Gennery, A. R., Hauck, F., Hawwari, A., Hickstein, D. D., Hoenig, M., Ikinciogullari, A., Klein, C., Kumar, A., Ifversen, M. R. S., Matthes, S., Metin, A., Neven, B., Pai, S-Y., Parikh, S. H., Picard, C., Renner, E. D., Sanal, Ö., Schulz, A. S., Schuster, F., Shah, N. N., Shereck, E. B., Slatter, M. A., Su, H. C., van Montfrans, J., Woessmann, W., Ziegler, J. B., Albert, M. H. & Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation and the European Society for Primary Immunodeficiencies, 03.2019, In: J ALLER CL IMM-PRACT. 7, 3, p. 848-855 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  424. Inositol hexakisphosphate increases the size of platelet aggregates

    Brehm, M. A., Klemm, U., Rehbach, C., Erdmann, N., Kolšek, K., Lin, H., Aponte-Santamaría, C., Gräter, F., Rauch, B. H., Riley, A. M., Mayr, G. W., Potter, B. V. L. & Windhorst, S., 03.2019, In: BIOCHEM PHARMACOL. 161, p. 14-25 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  425. Trypsin-encoding PRSS1-PRSS2 variations influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report

    Wolthers, B. O., Frandsen, T. L., Patel, C. J., Abaji, R., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Grosjean, M., Krajinovic, M., Larsen, E., Liang, D-C., Möricke, A., Rasmussen, K. K., Samarasinghe, S., Silverman, L. B., van der Sluis, I. M., Stanulla, M., Tulstrup, M., Yadav, R., Yang, W., Zapotocka, E., Gupta, R. & Schmiegelow, K., 03.2019, In: HAEMATOLOGICA. 104, 3, p. 556-563 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  426. Gliosarcoma Is Driven by Alterations in PI3K/Akt, RAS/MAPK Pathways and Characterized by Collagen Gene Expression Signature

    Wojtas, B., Gielniewski, B., Wojnicki, K., Maleszewska, M., Mondal, S. S., Nauman, P., Grajkowska, W., Glass, R., Schüller, U., Herold-Mende, C. & Kaminska, B., 27.02.2019, In: CANCERS. 11, 3

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  427. Dynamic 18F-FET PET is a powerful imaging biomarker in gadolinium-negative gliomas

    Kunz, M., Albert, N. L., Unterrainer, M., la Fougere, C., Egensperger, R., Schüller, U., Lutz, J., Kreth, S., Tonn, J-C., Kreth, F-W. & Thon, N., 14.02.2019, In: NEURO-ONCOLOGY. 21, 2, p. 274-284 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  428. Medulloblastoma

    Northcott, P. A., Robinson, G. W., Kratz, C. P., Mabbott, D. J., Pomeroy, S. L., Clifford, S. C., Rutkowski, S., Ellison, D. W., Malkin, D., Taylor, M. D., Gajjar, A. & Pfister, S. M., 14.02.2019, In: NAT REV DIS PRIMERS. 5, 1, p. 11

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  429. Proteogenomic systems analysis identifies targeted therapy resistance mechanisms in EGFR-mutated lung cancer

    Treue, D., Bockmayr, M., Stenzinger, A., Heim, D., Hester, S. & Klauschen, F., 01.02.2019, In: INT J CANCER. 144, 3, p. 545-557 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  430. Manifestations and Treatment of Adult-onset Symptomatic Optic Pathway Glioma in Neurofibromatosis Type 1

    Mehlan, J., Schüttauf, F., Salamon, J. M., Kordes, U., Friedrich, R. E. & Mautner, V-F., 02.2019, In: ANTICANCER RES. 39, 2, p. 827-831 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  431. Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor

    Xu, E-R., von Bülow, S., Chen, P-C., Lenting, P. J., Kolšek, K., Aponte-Santamaría, C., Simon, B., Foot, J., Obser, T., Schneppenheim, R., Gräter, F., Denis, C. V., Wilmanns, M. & Hennig, J., 24.01.2019, In: BLOOD. 133, 4, p. 366-376 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  432. The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

    Schneppenheim, R., Hellermann, N., Brehm, M. A., Klemm, U., Obser, T., Huck, V., Schneider, S. W., Denis, C. V., Tischer, A., Auton, M., März, W., Xu, E-R., Wilmanns, M. & Zotz, R. B., 24.01.2019, In: BLOOD. 133, 4, p. 356-365 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  433. Mutual Regulation of TLR/NLR and CEACAM1 in the Intestinal Microvasculature: Implications for IBD Pathogenesis and Therapy

    Schirbel, A., Rebert, N., Sadler, T., West, G., Rieder, F., Wagener, C., Horst, A., Sturm, A., de la Motte, C. & Fiocchi, C., 10.01.2019, In: INFLAMM BOWEL DIS. 25, 2, p. 294-305 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  434. Contrast enhancement is a prognostic factor in IDH1/2 mutant, but not in wild-type WHO grade II/III glioma as confirmed by machine learning

    Suchorska, B., Schüller, U., Biczok, A., Lenski, M., Albert, N. L., Giese, A., Kreth, F-W., Ertl-Wagner, B., Tonn, J-C. & Ingrisch, M., 01.2019, In: EUR J CANCER. 107, p. 15-27 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  435. Daunorubicin during delayed intensification decreases the incidence of infectious complications - a randomized comparison in trial CoALL 08-09

    Schramm, F., Zimmermann, M., Jorch, N., Pekrun, A., Borkhardt, A., Imschweiler, T., Christiansen, H., Faber, J., Feuchtinger, T., Schmid, I., Beron, G., Horstmann, M. A. & Escherich, G., 01.2019, In: LEUKEMIA LYMPHOMA. 60, 1, p. 60-68 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  436. Gemtuzumab Ozogamicin in children with relapsed or refractory acute myeloid leukemia: a report by Berlin-Frankfurt-Münster study group

    Niktoreh, N., Lerius, B., Zimmermann, M., Gruhn, B., Escherich, G., Bourquin, J-P., Dworzak, M., Sramkova, L., Rossig, C., Creutzig, U., Reinhardt, D. & Rasche, M., 01.2019, In: HAEMATOLOGICA. 104, 1, p. 120-127 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  437. Long-term follow-up of Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor

    Biondi, A., Cario, G., De Lorenzo, P., Castor, A., Conter, V., Leoni, V., Gandemer, V., Pieters, R., Stary, J., Escherich, G., Campbell, M., Attarbaschi, A., Li, C-K., Vora, A., Bradtke, J., Saha, V., Valsecchi, M. G. & Schrappe, M., 01.2019, In: HAEMATOLOGICA. 104, 1, p. e13-e16

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  438. Osteonecrosis in children with acute lymphoblastic leukemia at initial diagnosis and prior to any chemotherapy

    Krull, K., Kunstreich, M., Bronsema, A., Bleckmann, K., Classen, C-F., Erdlenbruch, B., Jorch, N., Kolb, R., Leipold, A., Moser, O., Prokop, A., Scheurlen, W., Steinbach, D., Klasen-Sansone, J., Klee, D., Escherich, G., Moericke, A., Schrappe, M., Borkhardt, A. & Kuhlen, M., 01.2019, In: LEUKEMIA LYMPHOMA. 60, 1, p. 78-84

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  439. Advancing multimer analysis of von Willebrand factor by single-molecule AFM imaging

    Löf, A., König, G., Schneppenheim, S., Schneppenheim, R., Benoit, M., Budde, U., Müller, J. P. & Brehm, M. A., 2019, In: PLOS ONE. 14, 1, p. e0210963

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  440. Haematopoietic Stem Cell Transplantation for Primary Haemophagocytic Lymphohistiocytosis

    Lehmberg, K., Moshous, D. & Booth, C., 2019, In: FRONT PEDIATR. 7, p. 435

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  441. Minimal Disseminated and Minimal Residual Disease in Pediatric Non-Hodgkin Lymphoma

    Mussolin, L., Damm-Welk, C. & Wößmann, W., 2019, Non-Hodgkin´s Lymphoma in Children and Adolescence. Abla, O. & Attarbaschi, A. (eds.). 1 ed. Cham: Springer, p. 119 - 129 11 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesEducation

  442. Risikofaktoren für einen gemischten Chimerismus nach Stammzelltransplantation mit Treosulfan- oder Melphalanbasierter Konditionierung bei Kindern und Jugendlichen mit primärer Hämophagozytischer Lymphohistiozytose

    Wustrau, K., Albert, M. H., Bader, P., Beier, R., Burkhardt, B., Chada, M., Greil, J., Gruhn, B., Kühl, J-S., Lang, P., Meisel, R., Schulz, A., Seidel, M., Speckmann, C., Sykora, K-W., Wawer, A., Wößmann, W., Ozga, A-K., Janka-Schaub, G., Ehl, S., Müller, I. & Lehmberg, K., 2019, Monatsschrift Kinderheilkunde > Ausgabe 7/2018 : Abstracts der 91. Wissenschaftlichen Halbjahrestagung der Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH). Vol. 01.07.2018 | Abstracts | Ausgabe 7/2018 . p. 646-647

    Research output: SCORING: Contribution to book/anthologyConference contribution - Published abstract for conference with selection processResearchpeer-review

  443. The German National Registry of Primary Immunodeficiencies (2012-2017)

    El-Helou, S. M., Biegner, A-K., Bode, S., Ehl, S. R., Heeg, M., Maccari, M. E., Ritterbusch, H., Speckmann, C., Rusch, S., Scheible, R., Warnatz, K., Atschekzei, F., Beider, R., Ernst, D., Gerschmann, S., Jablonka, A., Mielke, G., Schmidt, R. E., Schürmann, G., Sogkas, G., Baumann, U. H., Klemann, C., Viemann, D., von Bernuth, H., Krüger, R., Hanitsch, L. G., Scheibenbogen, C. M., Wittke, K., Albert, M. H., Eichinger, A., Hauck, F., Klein, C., Rack-Hoch, A., Sollinger, F. M., Avila, A., Borte, M., Borte, S., Fasshauer, M., Hauenherm, A., Kellner, N., Müller, A. H., Ülzen, A., Bader, P., Bakhtiar, S., Lee, J-Y., Heß, U., Schubert, R., Wölke, S., Zielen, S., Ghosh, S., Laws, H-J., Neubert, J., Oommen, P. T., Hönig, M., Schulz, A., Steinmann, S., Schwarz, K., Dückers, G., Lamers, B., Langemeyer, V., Niehues, T., Shai, S., Graf, D., Müglich, C., Schmalzing, M. T., Schwaneck, E. C., Tony, H-P., Dirks, J., Haase, G., Liese, J. G., Morbach, H., Foell, D., Hellige, A., Wittkowski, H., Masjosthusmann, K., Geberzahn, L., Hedrich, C. M., Müller, C., Rösen-Wolff, A., Roesler, J., Zimmermann, A., Behrends, U., Rieber, N., Schauer, U., Handgretinger, R., Holzer, U., Henes, J., Kanz, L., Boesecke, C., Rockstroh, J. K., Schwarze-Zander, C., Wasmuth, J-C., Dilloo, D., Hülsmann, B., Schönberger, S., Schreiber, S., Zeuner, R., Ankermann, T., von Bismarck, P., Huppertz, H-I., Kaiser-Labusch, P., Greil, J., Jakoby, D., Kulozik, A. E., Metzler, M., Naumann-Bartsch, N., Sobik, B., Graf, N., Heine, S., Kobbe, R., Lehmberg, K., Müller, I., Herrmann, F., Horneff, G., Klein, A., Peitz, J., Schmidt, N., Bielack, S., Groß-Wieltsch, U., Classen, C. F., Klasen, J., Deutz, P., Kamitz, D., Lassay, L., Tenbrock, K., Wagner, N., Bernbeck, B., Brummel, B., Lara-Villacanas, E., Münstermann, E., Schneider, D. T., Tietsch, N., Westkemper, M., Weiß, M., Kramm, C., Kühnle, I., Kullmann, S., Girschick, H., Specker, C., Vinnemeier-Laubenthal, E., Haenicke, H., Schweigerer, L., Müller, T. G., Stiefel, M., Belohradsky, B. H., Soetedjo, V., Kindle, G. & Grimbacher, B., 2019, In: FRONT IMMUNOL. 10, p. 1272

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  444. Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow

    Jagau, H., Behrens, I-K., Lahme, K., Lorz, G., Köster, R. W., Schneppenheim, R., Obser, T., Brehm, M. A., König, G., Kohler, T. P., Rohde, M., Frank, R., Tegge, W., Fulde, M., Hammerschmidt, S., Steinert, M. & Bergmann, S., 2019, In: FRONT MICROBIOL. 10, p. 511

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  445. 2018
  446. Biology and Treatment of Hemophagocytic Lymphohistiocytosis

    Janka-Schaub, G., 31.12.2018, In: Iran J Blood Cancer. 10, 4, p. 108-113

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  447. Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge

    Shemer, A., Grozovski, J., Tay, T. L., Tao, J., Volaski, A., Süß, P., Ardura-Fabregat, A., Gross-Vered, M., Kim, J-S., David, E., Chappell-Maor, L., Thielecke, L., Glass, C. K., Cornils, K., Prinz, M. & Jung, S., 06.12.2018, In: NAT COMMUN. 9, 1, p. 5206

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  448. A track of the clones: new developments in cellular barcoding

    Lyne, A-M., Kent, D. G., Laurenti, E., Cornils, K., Glauche, I. & Perié, L., 12.2018, In: EXP HEMATOL. 68, p. 15-20 6 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  449. Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface

    Moghaddas, F., Zeng, P., Zhang, Y., Schützle, H., Brenner, S., Hofmann, S. R., Berner, R., Zhao, Y., Lu, B., Chen, X., Zhang, L., Cheng, S., Winkler, S., Lehmberg, K., Canna, S. W., Czabotar, P. E., Wicks, I. P., De Nardo, D., Hedrich, C. M., Zeng, H. & Masters, S. L., 12.2018, In: J ALLERGY CLIN IMMUN. 142, 6, p. 1956-1967.e6

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  450. Characterization of Diffuse Gliomas With Histone H3-G34 Mutation by MRI and Dynamic 18F-FET PET

    Vettermann, F. J., Felsberg, J., Reifenberger, G., Hasselblatt, M., Forbrig, R., Berding, G., la Fougère, C., Galldiks, N., Schittenhelm, J., Weis, J., Albert, N. L. & Schüller, U., 12.2018, In: CLIN NUCL MED. 43, 12, p. 895-898 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  451. Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial

    Biondi, A., Gandemer, V., De Lorenzo, P., Cario, G., Campbell, M., Castor, A., Pieters, R., Baruchel, A., Vora, A., Leoni, V., Stary, J., Escherich, G., Li, C-K., Cazzaniga, G., Cavé, H., Bradtke, J., Conter, V., Saha, V., Schrappe, M. & Grazia Valsecchi, M., 12.2018, In: LANCET HAEMATOL. 5, 12, p. e641-e652

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  452. PDX models recapitulate the genetic and epigenetic landscape of pediatric T-cell leukemia

    Richter-Pechańska, P., Kunz, J. B., Bornhauser, B., von Knebel Doeberitz, C., Rausch, T., Erarslan-Uysal, B., Assenov, Y., Frismantas, V., Marovca, B., Waszak, S. M., Zimmermann, M., Seemann, J., Happich, M., Stanulla, M., Schrappe, M., Cario, G., Escherich, G., Bakharevich, K., Kirschner-Schwabe, R., Eckert, C., Muckenthaler, M. U., Korbel, J. O., Bourquin, J-P. & Kulozik, A. E., 12.2018, In: EMBO MOL MED. 10, 12, p. e9443

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  453. Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial

    Goschzik, T., Schwalbe, E. C., Hicks, D., Smith, A., Zur Muehlen, A., Figarella-Branger, D., Doz, F., Rutkowski, S., Lannering, B., Pietsch, T. & Clifford, S. C., 12.2018, In: LANCET ONCOL. 19, 12, p. 1602-1616 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  454. Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis

    Lucchini, G., Marsh, R., Gilmour, K., Worth, A., Nademi, Z., Rao, A., Booth, C., Amrolia, P., Silva, J., Chiesa, R., Wynn, R., Lehmberg, K., Astigarraga, I., Güngör, T., Stary, J., Moshous, D., Ifversen, M., Zinn, D., Jordan, M., Kumar, A., Yasumi, T., Veys, P. & Rao, K., 08.11.2018, In: BLOOD. 132, 19, p. 2088-2096 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  455. Impact of Whole Lung Irradiation on Survival Outcome in Patients With Lung Relapsed Ewing Sarcoma

    Scobioala, S., Ranft, A., Wolters, H., Jabar, S., Paulussen, M., Timmermann, B., Juergens, H., Hassenpflug, W., Klingebiel, T., Elsayad, K., Eich, H. T. & Dirksen, U., 01.11.2018, In: INT J RADIAT ONCOL. 102, 3, p. 584-592 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  456. Combined inhibition of receptor tyrosine and p21-activated kinases as a therapeutic strategy in childhood ALL

    Siekmann, I-K., Dierck, K., Prall, S., Klokow, M., Strauss, J., Buhs, S., Wrzeszcz, A., Bockmayr, M., Beck, F., Trochimiuk, M., Gottschling, K., Martens, V., Khosh-Naucke, M., Gerull, H., Müller, J., Behrmann, L., Blohm, M., Zahedi, R. P., Jeremias, I., Sickmann, A., Nollau, P. & Horstmann, M. A., 09.10.2018, In: Blood Adv. 2, 19, p. 2554-2567 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  457. Neuroimaging findings in children with hereditary hemophagocytic lymphohistiocytosis – report from the German reference center

    Löbel, U., Wustrau, K., Müller, I., Janka-Schaub, G., Fiehler, J. & Lehmberg, K., 03.10.2018, NeuroRAD 2018 - 53. Jahrestagung der Deutschen Gesellschaft für Neuroradiologe e.V..

    Research output: SCORING: Contribution to book/anthologyConference contribution - PosterResearch

  458. Allogeneic haematopoietic stem cell transplantation eliminates alloreactive inhibitory antibodies after liver transplantation for bile salt export pump deficiency

    Brinkert, F., Pukite, I., Krebs-Schmitt, D., Briem-Richter, A., Stindt, J., Häussinger, D., Keitel, V., Müller, I. & Grabhorn, E., 10.2018, In: J HEPATOL. 69, 4, p. 961-965 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  459. Langzeitbeobachtung ehemaliger krebskranker Kinder und Jugendlicher

    Langer, T., Grabow, D., Kaatsch, P., Creutzig, U., Eggert, A., Escherich, G. & Calaminus, G., 10.2018, In: KLIN PADIATR. 230, 6, p. 291-298 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  460. Low incidence of symptomatic osteonecrosis after allogeneic HSCT in children with high-risk or relapsed ALL - results of the ALL-SCT 2003 trial

    Kuhlen, M., Bader, P., Sauer, M., Albert, M. H., Gruhn, B., Güngör, T., Kropshofer, G., Lang, P., Lawitschka, A., Metzler, M., Pentek, F., Rossig, C., Schlegel, P. G., Schrappe, M., Schrum, J., Schulz, A., Schwinger, W., von Stackelberg, A., Strahm, B., Suttorp, M., Luettichau, I. T., Wößmann, W., Borkhardt, A., Meisel, R., Poetschger, U., Glogova, E. & Peters, C., 10.2018, In: BRIT J HAEMATOL. 183, 1, p. 104-109 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  461. Scoring of tumor-infiltrating lymphocytes: from visual estimation to machine learning

    Klauschen, F., Müller, K-R., Binder, A., Bockmayr, M., Hägele, M., Seegerer, P., Wienert, S., Pruneri, G., de Maria, S., Badve, S., Michiels, S., Nielsen, T. O., Adams, S., Savas, P., Symmans, F., Willis, S., Gruosso, T., Park, M., Haibe-Kains, B., Gallas, B., Thompson, A. M., Cree, I., Sotiriou, C., Solinas, C., Preusser, M., Hewitt, S. M., Rimm, D., Viale, G., Loi, S., Loibl, S., Salgado, R., Denkert, C. & International Immuno-Oncology Biomarker Working Group, 10.2018, In: SEMIN CANCER BIOL. 52, Pt 2, p. 151-157 7 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  462. Risk factors for mixed chimerism after stem cell transplantation with treosulfan or melphalan based conditioning regimens in children and adolescents with primary hemophagocytic lymphohistocytosis

    Wustrau, K., Albert, M. H., Bader, P., Beier, R., Burkhardt, B., Chada, M., Greil, J., Gruhn, B., Kühl, J-S., Lang, P., Meisel, R., Schulz, A., Seidel, M., Speckmann, C., Sykora, K-W., Wawer, A., Wößmann, W., Ozga, A-K., Ehl, S., Müller, I. & Lehmberg, K., 24.09.2018, Bone Marrow Transplantation (2018) Abstracts Collection: The 44th Annual Meeting of the European Society for Blood and Marrow Transplantation:Physicians Oral Session.

    Research output: SCORING: Contribution to book/anthologyConference contribution - Published abstract for conference with selection processResearchpeer-review

  463. Supplementary Therapeutic Recommendations

    Hassenpflug, W-A. & Schneppenheim, R., 14.09.2018, In: DTSCH ARZTEBL INT. 155, 37, p. 608

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  464. Recommendations for the Use of Etoposide-Based Therapy and Bone Marrow Transplantation for the Treatment of HLH: Consensus Statements by the HLH Steering Committee of the Histiocyte Society

    Ehl, S., Astigarraga, I., von Bahr Greenwood, T., Hines, M., Horne, A., Ishii, E., Janka, G., Jordan, M. B., La Rosée, P., Lehmberg, K., Machowicz, R., Nichols, K. E., Sieni, E., Wang, Z. & Henter, J-I., 12.09.2018, In: J ALLER CL IMM-PRACT. 6, 5, p. 1508-1517 10 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  465. Correction to: DNA methylation-based reclassification of olfactory neuroblastoma

    Capper, D., Engel, N. W., Stichel, D., Lechner, M., Glöss, S., Schmid, S., Kölsche, C., Schrimpf, D., Niesen, J., Wefers, A. K., Jones, D. T. W., Sill, M., Weigert, O., Ligon, K. L., Olar, A., Koch, A., Forster, M., Moran, S., Tirado, O. M., Sáinz-Jaspeado, M., Mora, J., Esteller, M., Alonso, J., Del Muro, X. G., Paulus, W., Felsberg, J., Reifenberger, G., Glatzel, M., Frank, S., Monoranu, C. M., Lund, V. J., von Deimling, A., Pfister, S., Buslei, R., Ribbat-Idel, J., Perner, S., Gudziol, V., Meinhardt, M. & Schüller, U., 09.2018, In: ACTA NEUROPATHOL. 136, 3, p. 505

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  466. T-cell gene therapy for perforin deficiency corrects cytotoxicity defects and prevents hemophagocytic lymphohistiocytosis manifestations

    Ghosh, S., Carmo, M., Calero-Garcia, M., Ricciardelli, I., Bustamante Ogando, J. C., Blundell, M. P., Schambach, A., Ashton-Rickardt, P. G., Booth, C., Ehl, S., Lehmberg, K., Thrasher, A. J. & Gaspar, H. B., 09.2018, In: J ALLERGY CLIN IMMUN. 142, 3, p. 904-913

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  467. Autologous Mesenchymal Stroma Cells Are Superior to Allogeneic Ones in Bone Defect Regeneration

    Rapp, A. E., Bindl, R., Erbacher, A., Kruchen, A., Rojewski, M., Schrezenmeier, H., Müller, I. & Ignatius, A., 25.08.2018, In: INT J MOL SCI. 19, 9

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  468. Is an infectious trigger always required for primary hemophagocytic lymphohistiocytosis? Lessons from in utero and neonatal disease

    Heeg, M., Ammann, S., Klemann, C., Panning, M., Falcone, V., Hengel, H., Lehmberg, K., Zur Stadt, U., Wustrau, K., Janka, G. & Ehl, S., 01.08.2018, In: PEDIATR BLOOD CANCER. 65, 11, p. e27344

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  469. Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group

    Rutkowski, S., Modena, P., Williamson, D., Kerl, K., Nysom, K., Pizer, B., Bartels, U., Puget, S., Doz, F., Michalski, A., von Hoff, K., Chevignard, M., Avula, S., Murray, M. J., Schönberger, S., Czech, T., Schouten-van Meeteren, A. Y. N., Kordes, U., Kramm, C. M., van Vuurden, D. G., Hulleman, E., Janssens, G. O., Solanki, G. A., van Veelen, M-L. C., Thomale, U., Schuhmann, M. U., Jones, C., Giangaspero, F., Figarella-Branger, D., Pietsch, T., Clifford, S. C., Pfister, S. M. & Van Gool, S. W., 08.2018, In: LANCET ONCOL. 19, 8, p. e419-e428

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  470. DNA methylation-based reclassification of olfactory neuroblastoma

    Capper, D., Engel, N. W., Stichel, D., Lechner, M., Glöss, S., Schmid, S., Koelsche, C., Schrimpf, D., Niesen, J., Wefers, A. K., Jones, D. T. W., Sill, M., Weigert, O., Ligon, K. L., Olar, A., Koch, A., Forster, M., Moran, S., Tirado, O. M., Sáinz-Japeado, M., Mora, J., Esteller, M., Alonso, J., Del Muro, X. G., Paulus, W., Felsberg, J., Reifenberger, G., Glatzel, M., Frank, S., Monoranu, C. M., Lund, V. J., von Deimling, A., Pfister, S., Buslei, R., Ribbat-Idel, J., Perner, S., Gudziol, V., Meinhardt, M. & Schüller, U., 08.2018, In: ACTA NEUROPATHOL. 136, 2, p. 255-271 17 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  471. Germline variants in SMARCB1 and other members of the BAF chromatin-remodeling complex across human disease entities: a meta-analysis

    Holsten, T., Bens, S., Oyen, F., Nemes, K., Hasselblatt, M., Kordes, U., Siebert, R., Frühwald, M. C., Schneppenheim, R. & Schüller, U., 08.2018, In: EUR J HUM GENET. 26, 8, p. 1083-1093 11 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  472. Heterogeneity within the PF-EPN-B ependymoma subgroup

    Cavalli, F. M. G., Hübner, J-M., Sharma, T., Luu, B., Sill, M., Zapotocky, M., Mack, S. C., Witt, H., Lin, T., Shih, D. J. H., Ho, B., Santi, M., Emery, L., Hukin, J., Dunham, C., McLendon, R. E., Lipp, E. S., Gururangan, S., Grossbach, A., French, P., Kros, J. M., van Veelen, M-L. C., Rao, A. A. N., Giannini, C., Leary, S., Jung, S., Faria, C. C., Mora, J., Schüller, U., Alonso, M. M., Chan, J. A., Klekner, A., Chambless, L. B., Hwang, E. I., Massimino, M., Eberhart, C. G., Karajannis, M. A., Lu, B., Liau, L. M., Zollo, M., Ferrucci, V., Carlotti, C., Tirapelli, D. P. C., Tabori, U., Bouffet, E., Ryzhova, M., Ellison, D. W., Merchant, T. E., Gilbert, M. R., Armstrong, T. S., Korshunov, A., Pfister, S. M., Taylor, M. D., Aldape, K., Pajtler, K. W., Kool, M. & Ramaswamy, V., 08.2018, In: ACTA NEUROPATHOL. 136, 2, p. 227-237 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  473. Pediatric acute lymphoblastic leukemia-Conquering the CNS across the choroid plexus

    März, M., Meyer, S., Erb, U., Georgikou, C., Horstmann, M. A., Hetjens, S., Weiß, C., Fallier-Becker, P., Vandenhaute, E., Ishikawa, H., Schroten, H., Dürken, M. & Karremann, M., 08.2018, In: LEUKEMIA RES. 71, p. 47-54 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  474. Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations

    Koelsche, C., Mynarek, M., Schrimpf, D., Bertero, L., Serrano, J., Sahm, F., Reuss, D. E., Hou, Y., Baumhoer, D., Vokuhl, C., Flucke, U., Petersen, I., Brück, W., Rutkowski, S., Zambrano, S. C., Garcia Leon, J. L., Diaz Coronado, R. Y., Gessler, M., Tirado, O. M., Mora, J., Alonso, J., Garcia Del Muro, X., Esteller, M., Sturm, D., Ecker, J., Milde, T., Pfister, S. M., Korshunov, A., Snuderl, M., Mechtersheimer, G., Schüller, U., Jones, D. T. W. & von Deimling, A., 08.2018, In: ACTA NEUROPATHOL. 136, 2, p. 327-337 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  475. Cellular stress induces erythrocyte assembly on intravascular von Willebrand factor strings and promotes microangiopathy

    Nicolay, J. P., Thorn, V., Daniel, C., Amann, K., Siraskar, B., Lang, F., Hillgruber, C., Goerge, T., Hoffmann, S., Gorzelanny, C., Huck, V., Mess, C., Obser, T., Schneppenheim, R., Fleming, I., Schneider, M. F. & Schneider, S. W., 19.07.2018, In: SCI REP-UK. 8, 1, p. 10945

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  476. Author Correction: The landscape of genomic alterations across childhood cancers

    Gröbner, S. N., Worst, B. C., Weischenfeldt, J., Buchhalter, I., Kleinheinz, K., Rudneva, V. A., Johann, P. D., Balasubramanian, G. P., Segura-Wang, M., Brabetz, S., Bender, S., Hutter, B., Sturm, D., Pfaff, E., Hübschmann, D., Zipprich, G., Heinold, M., Eils, J., Lawerenz, C., Erkek, S., Lambo, S., Waszak, S., Blattmann, C., Borkhardt, A., Kuhlen, M., Eggert, A., Fulda, S., Gessler, M., Wegert, J., Kappler, R., Baumhoer, D., Burdach, S., Kirschner-Schwabe, R., Kontny, U., Kulozik, A. E., Lohmann, D., Hettmer, S., Eckert, C., Bielack, S., Nathrath, M., Niemeyer, C., Richter, G. H., Schulte, J., Siebert, R., Westermann, F., Molenaar, J. J., Vassal, G., Witt, H., Burkhardt, B., Kratz, C. P., Witt, O., van Tilburg, C. M., Kramm, C. M., Fleischhack, G., Dirksen, U., Rutkowski, S., Frühwald, M., von Hoff, K., Wolf, S., Klingebiel, T., Koscielniak, E., Landgraf, P., Koster, J., Resnick, A. C., Zhang, J., Liu, Y., Zhou, X., Waanders, A. J., Zwijnenburg, D. A., Raman, P., Brors, B., Weber, U. D., Northcott, P. A., Pajtler, K. W., Kool, M., Piro, R. M., Korbel, J. O., Schlesner, M., Eils, R., Jones, D. T. W., Lichter, P., Chavez, L., Zapatka, M., Pfister, S. M. & ICGC PedBrain-Seq Project, 07.2018, In: NATURE. 559, 7714, p. E10

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  477. Integrated analysis of dynamic FET PET/CT parameters, histology, and methylation profiling of 44 gliomas

    Röhrich, M., Huang, K., Schrimpf, D., Albert, N. L., Hielscher, T., von Deimling, A., Schüller, U., Dimitrakopoulou-Strauss, A. & Haberkorn, U., 07.2018, In: EUR J NUCL MED MOL I. 45, 9, p. 1573-1584 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  478. Recurrence of Ewing sarcoma: Is detection by imaging follow-up protocol associated with survival advantage?

    Heinemann, M., Ranft, A., Langer, T., Jürgens, H., Kreyer, J., Vieth, V., Schäfers, M., Weckesser, M., Simon, T., Hassenpflug, W., Corbacioglu, S., Bielack, S., Mayer-Steinacker, R., Kühne, T., van den Berg, H., Gelderblom, H., Bauer, S., Stegger, L. & Dirksen, U., 07.2018, In: PEDIATR BLOOD CANCER. 65, 7, p. e27011

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  479. Inflammatory myofibroblastic tumors-A retrospective analysis of the Cooperative Weichteilsarkom Studiengruppe

    Kube, S., Vokuhl, C., Dantonello, T., Scheer, M., Hallmen, E., Feuchtgruber, S., Escherich, G., Niggli, F., Kuehnle, I., von Kalle, T., Bielack, S., Klingebiel, T. & Koscielniak, E., 06.2018, In: PEDIATR BLOOD CANCER. 65, 6, p. e27012

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  480. Reduced circulating B cells and plasma IgM levels are associated with decreased survival in sepsis - A meta-analysis

    Krautz, C., Maier, S. L., Brunner, M., Langheinrich, M., Giamarellos-Bourboulis, E. J., Gogos, C., Armaganidis, A., Kunath, F., Grützmann, R. & Weber, G. F., 06.2018, In: J CRIT CARE. 45, p. 71-75 5 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  481. Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort

    Waszak, S. M., Northcott, P. A., Buchhalter, I., Robinson, G. W., Sutter, C., Groebner, S., Grund, K. B., Brugières, L., Jones, D. T. W., Pajtler, K. W., Morrissy, A. S., Kool, M., Sturm, D., Chavez, L., Ernst, A., Brabetz, S., Hain, M., Zichner, T., Segura-Wang, M., Weischenfeldt, J., Rausch, T., Mardin, B. R., Zhou, X., Baciu, C., Lawerenz, C., Chan, J. A., Varlet, P., Guerrini-Rousseau, L., Fults, D. W., Grajkowska, W., Hauser, P., Jabado, N., Ra, Y-S., Zitterbart, K., Shringarpure, S. S., De La Vega, F. M., Bustamante, C. D., Ng, H-K., Perry, A., MacDonald, T. J., Hernáiz Driever, P., Bendel, A. E., Bowers, D. C., McCowage, G., Chintagumpala, M. M., Cohn, R., Hassall, T., Fleischhack, G., Eggen, T., Wesenberg, F., Feychting, M., Lannering, B., Schüz, J., Johansen, C., Andersen, T. V., Röösli, M., Kuehni, C. E., Grotzer, M., Kjaerheim, K., Monoranu, C. M., Archer, T. C., Duke, E., Pomeroy, S. L., Shelagh, R., Frank, S., Sumerauer, D., Scheurlen, W., Ryzhova, M. V., Milde, T., Kratz, C. P., Samuel, D., Zhang, J., Solomon, D. A., Marra, M., Eils, R., Bartram, C. R., von Hoff, K., Rutkowski, S., Ramaswamy, V., Gilbertson, R. J., Korshunov, A., Taylor, M. D., Lichter, P., Malkin, D., Gajjar, A., Korbel, J. O. & Pfister, S. M., 06.2018, In: LANCET ONCOL. 19, 6, p. 785-798 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  482. The extraordinary challenge of treating patients with congenital rhabdoid tumors-a collaborative European effort

    Nemes, K., Clément, N., Kachanov, D., Bens, S., Hasselblatt, M., Timmermann, B., Schneppenheim, R., Gerss, J., Siebert, R., Furtwängler, R., Bourdeaut, F., Frühwald, M. C. & EU-RHAB consortium, 06.2018, In: PEDIATR BLOOD CANCER. 65, p. e26999

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  483. Comment on: "Successful use of nitrous oxide during lumbar punctures: A call for nitrous oxide in pediatric oncology clinics"

    Forster, V., Escherich, G. & Halsey, C., 05.2018, In: PEDIATR BLOOD CANCER. 65, 5, p. e26930

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  484. The phosphotyrosine phosphatase SHP2 promotes anergy in chronic lymphocytic leukemia

    Schliffke, S., Buhs, S., Bolz, S., Gerull, H., von Wenserski, L., Riecken, K., Fehse, B., Nollau, P. & Binder, M., 12.04.2018, In: BLOOD. 131, 15, p. 1755-1758 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  485. Differences in maxillomandibular morphology among patients with mucopolysaccharidoses I, II, III, IV and VI: a retrospective MRI study

    Koehne, T., Köhn, A., Friedrich, R. E., Kordes, U., Schinke, T., Muschol, N. & Kahl-Nieke, B., 04.2018, In: CLIN ORAL INVEST. 22, 3, p. 1541-1549 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  486. Genetic and Functional Characterization of ADAMTS13 Variants in a Patient Cohort with Upshaw-Schulman Syndrome Investigated in Germany

    Hassenpflug, W. A., Obser, T., Bode, J., Oyen, F., Budde, U., Schneppenheim, S., Schneppenheim, R. & Brehm, M. A., 04.2018, In: THROMB HAEMOSTASIS. 118, 4, p. 709-722 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  487. Hypereosinophilia as Presenting Symptom of a Pre-B-ALL

    Maier, S. L., Zoghbi, A., Escherich, G. & Winkler, B., 04.2018, In: KLIN PADIATR. 230, 3, p. 160-161 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  488. RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia

    Jerchel, I. S., Hoogkamer, A. Q., Ariës, I. M., Steeghs, E. M. P., Boer, J. M., Besselink, N. J. M., Boeree, A., van de Ven, C., de Groot-Kruseman, H. A., de Haas, V., Horstmann, M. A., Escherich, G., Zwaan, C. M., Cuppen, E., Koudijs, M. J., Pieters, R. & den Boer, M. L., 04.2018, In: LEUKEMIA. 32, 4, p. 931-940 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  489. Sellar Region Atypical Teratoid/Rhabdoid Tumors (ATRT) in Adults Display DNA Methylation Profiles of the ATRT-MYC Subgroup

    Johann, P. D., Bens, S., Oyen, F., Wagener, R., Giannini, C., Perry, A., Raisanen, J. M., Reis, G. F., Nobusawa, S., Arita, K., Felsberg, J., Reifenberger, G., Agaimy, A., Buslei, R., Capper, D., Pfister, S. M., Schneppenheim, R., Siebert, R., Frühwald, M. C., Paulus, W., Kool, M. & Hasselblatt, M., 04.2018, In: AM J SURG PATHOL. 42, 4, p. 506-511 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  490. Interaction of von Willebrand factor domains with collagen investigated by single molecule force spectroscopy

    Posch, S., Obser, T., König, G., Schneppenheim, R., Tampé, R. & Hinterdorfer, P., 28.03.2018, In: J CHEM PHYS. 148, 12, p. 123310

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  491. Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma

    Merk, D. J., Ohli, J., Merk, N. D., Thatikonda, V., Morrissy, S., Schoof, M., Schmid, S. N., Harrison, L., Filser, S., Ahlfeld, J., Erkek, S., Raithatha, K., Andreska, T., Weißhaar, M., Launspach, M., Neumann, J. E., Shakarami, M., Plenker, D., Marra, M. A., Li, Y., Mungall, A. J., Moore, R. A., Ma, Y., Jones, S. J. M., Lutz, B., Ertl-Wagner, B., Rossi, A., Wagener, R., Siebert, R., Jung, A., Eberhart, C. G., Lach, B., Sendtner, M., Pfister, S. M., Taylor, M. D., Chavez, L., Kool, M. & Schüller, U., 26.03.2018, In: DEV CELL. 44, 6, p. 709-724.e6

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  492. DNA methylation-based classification of central nervous system tumours

    Capper, D., Jones, D. T. W., Sill, M., Hovestadt, V., Schrimpf, D., Sturm, D., Koelsche, C., Sahm, F., Chavez, L., Reuss, D. E., Kratz, A., Wefers, A. K., Huang, K., Pajtler, K. W., Schweizer, L., Stichel, D., Olar, A., Engel, N. W., Lindenberg, K., Harter, P. N., Braczynski, A. K., Plate, K. H., Dohmen, H., Garvalov, B. K., Coras, R., Hölsken, A., Hewer, E., Bewerunge-Hudler, M., Schick, M., Fischer, R., Beschorner, R., Schittenhelm, J., Staszewski, O., Wani, K., Varlet, P., Pages, M., Temming, P., Lohmann, D., Selt, F., Witt, H., Milde, T., Witt, O., Aronica, E., Giangaspero, F., Rushing, E., Scheurlen, W., Geisenberger, C., Rodriguez, F. J., Becker, A., Preusser, M., Haberler, C., Bjerkvig, R., Cryan, J., Farrell, M., Deckert, M., Hench, J., Frank, S., Serrano, J., Kannan, K., Tsirigos, A., Brück, W., Hofer, S., Brehmer, S., Seiz-Rosenhagen, M., Hänggi, D., Hans, V., Rozsnoki, S., Hansford, J. R., Kohlhof, P., Kristensen, B. W., Lechner, M., Lopes, B., Mawrin, C., Ketter, R., Kulozik, A., Khatib, Z., Heppner, F., Koch, A., Jouvet, A., Keohane, C., Mühleisen, H., Mueller, W., Pohl, U., Prinz, M., Benner, A., Zapatka, M., Gottardo, N. G., Driever, P. H., Kramm, C. M., Müller, H. L., Rutkowski, S., von Hoff, K., Frühwald, M. C., Gnekow, A., Fleischhack, G., Tippelt, S., Calaminus, G., Monoranu, C-M., Perry, A., Jones, C., Jacques, T. S., Radlwimmer, B., Gessi, M., Pietsch, T., Schramm, J., Schackert, G., Westphal, M., Reifenberger, G., Wesseling, P., Weller, M., Collins, V. P., Blümcke, I., Bendszus, M., Debus, J., Huang, A., Jabado, N., Northcott, P. A., Paulus, W., Gajjar, A., Robinson, G. W., Taylor, M. D., Jaunmuktane, Z., Ryzhova, M., Platten, M., Unterberg, A., Wick, W., Karajannis, M. A., Mittelbronn, M., Acker, T., Hartmann, C., Aldape, K., Schüller, U., Buslei, R., Lichter, P., Kool, M., Herold-Mende, C., Ellison, D. W., Hasselblatt, M., Snuderl, M., Brandner, S., Korshunov, A., von Deimling, A. & Pfister, S. M., 22.03.2018, In: NATURE. 555, 7697, p. 469-474 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  493. The landscape of genomic alterations across childhood cancers

    Gröbner, S. N., Worst, B. C., Weischenfeldt, J., Buchhalter, I., Kleinheinz, K., Rudneva, V. A., Johann, P. D., Balasubramanian, G. P., Segura-Wang, M., Brabetz, S., Bender, S., Hutter, B., Sturm, D., Pfaff, E., Hübschmann, D., Zipprich, G., Heinold, M., Eils, J., Lawerenz, C., Erkek, S., Lambo, S., Waszak, S., Blattmann, C., Borkhardt, A., Kuhlen, M., Eggert, A., Fulda, S., Gessler, M., Wegert, J., Kappler, R., Baumhoer, D., Burdach, S., Kirschner-Schwabe, R., Kontny, U., Kulozik, A. E., Lohmann, D., Hettmer, S., Eckert, C., Bielack, S., Nathrath, M., Niemeyer, C., Richter, G. H., Schulte, J., Siebert, R., Westermann, F., Molenaar, J. J., Vassal, G., Witt, H., Burkhardt, B., Kratz, C. P., Witt, O., van Tilburg, C. M., Kramm, C. M., Fleischhack, G., Dirksen, U., Rutkowski, S., Frühwald, M., von Hoff, K., Wolf, S., Klingebiel, T., Koscielniak, E., Landgraf, P., Koster, J., Resnick, A. C., Zhang, J., Liu, Y., Zhou, X., Waanders, A. J., Zwijnenburg, D. A., Raman, P., Brors, B., Weber, U. D., Northcott, P. A., Pajtler, K. W., Kool, M., Piro, R. M., Korbel, J. O., Schlesner, M., Eils, R., Jones, D. T. W., Lichter, P., Chavez, L., Zapatka, M., Pfister, S. M. & ICGC PedBrain-Seq Project, 15.03.2018, In: NATURE. 555, 7696, p. 321-327 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  494. Group 3 medulloblastoma in a patient with a GYS2 germline mutation and glycogen storage disease 0a

    Holsten, T., Tsiakas, K., Kordes, U., Bison, B., Pietsch, T., Rutkowski, S., Santer, R. & Schüller, U., 03.2018, In: CHILD NERV SYST. 34, 3, p. 581-584 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  495. Medulloblastoma in adults: A retrospective single institution analysis

    Hadi, I., Roengvoraphoj, O., Niyazi, M., Roeder, F., Schüller, U., Belka, C. & Nachbichler, S. B., 03.2018, In: STRAHLENTHER ONKOL. 194, 3, p. 225-234 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  496. Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07)

    Beier, D., Proescholdt, M., Reinert, C., Pietsch, T., Jones, D. T. W., Pfister, S. M., Hattingen, E., Seidel, C., Dirven, L., Luerding, R., Reijneveld, J., Warmuth-Metz, M., Bonsanto, M., Bremer, M., Combs, S. E., Rieken, S., Herrlinger, U., Kuntze, H., Mayer-Steinacker, R., Moskopp, D., Schneider, T., Beringer, A., Schlegel, U., Stummer, W., Welker, H., Weyerbrock, A., Paulsen, F., Rutkowski, S., Weller, M., Wick, W., Kortmann, R-D., Bogdahn, U. & Hau, P., 19.02.2018, In: NEURO-ONCOLOGY. 20, 3, p. 400-410 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  497. A biophysical view on von Willebrand factor activation

    Löf, A., Müller, J. P. & Brehm, M. A., 02.2018, In: J CELL PHYSIOL. 233, 2, p. 799-810 12 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  498. Glial papillary tumour of the spinal cord with SMARCB1/INI1-loss and favourable long-term outcome

    Hasselblatt, M., Kurniawan, A. D., Rozsnoki, S., Johann, P. D., Bens, S., Oyen, F., Schneppenheim, R., Siebert, R., Capper, D., Kool, M., Schul, C. & Paulus, W., 02.2018, In: NEUROPATH APPL NEURO. 44, 2, p. 229-232 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  499. Retrospective analysis on thermal injuries in children-Demographic, etiological and clinical data of German and Austrian pediatric hospitals 2006-2015-Approaching the new German burn registry

    Tegtmeyer, L. C., Herrnstadt, G. R., Maier, S. L., Thamm, O. C., Klinke, M., Reinshagen, K. & Koenigs, I., 02.2018, In: BURNS. 44, 1, p. 150-157 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  500. High STAP1 expression in DUX4-rearranged cases is not suitable as therapeutic target in pediatric B-cell precursor acute lymphoblastic leukemia

    Steeghs, E. M. P., Bakker, M., Hoogkamer, A. Q., Boer, J. M., Hartman, Q. J., Stalpers, F., Escherich, G., de Haas, V., de Groot-Kruseman, H. A., Pieters, R. & den Boer, M. L., 12.01.2018, In: SCI REP-UK. 8, 1, p. 693

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  501. Multilayered omics-based analysis of a head and neck cancer model of cisplatin resistance reveals intratumoral heterogeneity and treatment-induced clonal selection

    Niehr, F., Eder, T., Pilz, T., Konschak, R., Treue, D., Klauschen, F., Bockmayr, M., Türkmen, S., Jöhrens, K., Budach, V. & Tinhofer, I., 01.01.2018, In: CLIN CANCER RES. 24, 1, p. 158-168 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  502. CD34+ selected stem cell boosts can improve poor graft function after paediatric allogeneic stem cell transplantation

    Mainardi, C., Ebinger, M., Enkel, S., Feuchtinger, T., Teltschik, H-M., Eyrich, M., Schumm, M., Rabsteyn, A., Schlegel, P., Seitz, C., Schwarze, C-P., Müller, I., Greil, J., Bader, P., Schlegel, P-G., Martin, D., Holzer, U., Döring, M., Handgretinger, R. & Lang, P., 01.2018, In: BRIT J HAEMATOL. 180, 1, p. 90-99 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  503. Postmortem MR diffusion-weighted imaging of the liver: time-behavior of the hepatic apparent diffusion coefficient in the early death interval

    Keller, S., Schmidt, T. M., Kim, A. C., Fischer, R., Heinemann, A., Adam, G. & Yamamura, J., 01.2018, In: INT J LEGAL MED. 132, 1, p. 263-268 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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