Research ExplorerScientific StaffManfred Jücker

Prof.Dr. ID: 59733

Manfred Jücker

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Affiliations

Publications

Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

The Functional Roles of the Src Homology 2 Domain-Containing Inositol 5-Phosphatases SHIP1 and SHIP2 in the Pathogenesis of Human Diseases

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Generating Patient-Derived HCC Cell Lines Suitable for Predictive In Vitro and In Vivo Drug Screening by Orthotopic Transplantation

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Targeted hyperactivation of AKT through inhibition of ectopic expressed SHIP1 induces cell death in colon carcinoma cells and derived metastases

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Impact of AKT1 on cell invasion and radiosensitivity in a triple negative breast cancer cell line developing brain metastasis

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Activated Src kinases downstream of BCR-ABL and Flt3 induces proteasomal degradation of SHIP1 by phosphorylation of tyrosine 1021

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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projects

031L0226 Alternativmethoden

Project: Research

Characterization of CYTL1

Project: Research

Untersuchung zur Funktion des PI3-Kinase

Project: Research

Stipendium DAAD

Project: Research

Untersuchungen zur Funktion von SHIP1

Project: Research

Untersuchungen zur Funktion von SHIP1 un

Project: Research

20/86 Otto Stiftg. Functional analysis

Project: Research

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