Research ExplorerScientific StaffManfred Jücker

Prof.Dr. ID: 59733

Manfred Jücker

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Affiliations

Publications

K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Generating Patient-Derived HCC Cell Lines Suitable for Predictive In Vitro and In Vivo Drug Screening by Orthotopic Transplantation

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Targeted hyperactivation of AKT through inhibition of ectopic expressed SHIP1 induces cell death in colon carcinoma cells and derived metastases

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Impact of AKT1 on cell invasion and radiosensitivity in a triple negative breast cancer cell line developing brain metastasis

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Activated Src kinases downstream of BCR-ABL and Flt3 induces proteasomal degradation of SHIP1 by phosphorylation of tyrosine 1021

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

The Role of PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma Metabolism

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Reduced expression and activity of patient-derived SHIP1 phosphatase domain mutants

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

JAK2-V617F is a negative regulation factor of SHIP1 protein and thus influences the AKT signaling pathway in patients with Myeloproliferative Neoplasm (MPN)

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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projects

031L0226 Alternativmethoden

Project: Research

Characterization of CYTL1

Project: Research

Untersuchung zur Funktion des PI3-Kinase

Project: Research

Stipendium DAAD

Project: Research

Untersuchungen zur Funktion von SHIP1

Project: Research

Untersuchungen zur Funktion von SHIP1 un

Project: Research

20/86 Otto Stiftg. Functional analysis

Project: Research

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