Department of Biochemistry and Molecular Cell Biology
Publications
- 2012
Nicotinic Acid Adenine Dinucleotide 2'-Phosphate (NAADP) Binding Proteins in T-Lymphocytes
Walseth, T. F., Lin-Moshier, Y., Weber, K., Marchant, J. S., Slama, J. T. & Guse, A. H., 01.06.2012, In: Messenger (Los Angel). 1, 1, p. 86-94 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite
Cabrera, A., Herrmann, S., Warszta, D., Santos, J. M., John Peter, A. T., Kono, M., Debrouver, S., Jacobs, T., Spielmann, T., Ungermann, C., Soldati-Favre, D. & Gilberger, T. W., 01.10.2012, In: TRAFFIC. 13, 10, p. 1335-50 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Assessing language indicators across the lifespan within the German National Educational Panel Study (NEPS)
Berendes, K., Weinert, S., Zimmermann, S. & Artelt, C., 2013, In: J EDUC RES ONLINE-JE. 5, 2, p. 15-49Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Eisenmessung mittels MRT-R2* und Kalibrierung in der Milz
Yamamura, J., Schönnagel, B., Brehmer, M., Berliner, C., Nielsen, P., Adam, G. & Fischer, R., 2013, In: ROFO-FORTSCHR RONTG. 185, S 01, p. VO307_6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo.
Dieckmann, M., Beil, F. T., Müller, B., Bartelt, A., Marshall, R. P., Köhne, T., Amling, M., Ruether, W., Cooper, J. A., Humphries, S. E., Herz, J. & Niemeier, A., 2013, In: J BONE MINER RES. 28, 2, p. 236-245 10 p., 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased expression of transthyretin in leptin-deficient ob/ob mice is not causative for their major phenotypic abnormalities.
Rendenbach, C., Ganswindt, S., Seitz, S., Barvencik, F., Hübner, A. K., Baranowsky, A., Streichert, T., Niemeier, A., Heeren, J., Amling, M., Bartelt, A. & Schinke, T., 2013, In: J NEUROENDOCRINOL. 25, 1, p. 14-22 9 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Kardiale, pankreatische und hepatische Eisenmessung bei Patienten mit hereditärer Hämochromatose
Yamamura, J., Schönnagel, B., Brehmer, M., Berliner, C., Nielsen, P., Adam, G. & Fischer, R., 2013, In: ROFO-FORTSCHR RONTG. 185, S 01, p. VO402_3Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Leber- und Milzvolumenmessung in Patienten mit Eisenüberladung im Vergleich zu Lebereisen mit quantitativer MRT und biomagnetischer Suszeptometrie
Yamamura, J., Schönnagel, B., Berliner, C., Brehmer, M., Nielsen, P., Adam, G. & Fischer, R., 2013, In: ROFO-FORTSCHR RONTG. 185, S 01, p. VO211_2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling
Wolf, I., Fliegert, R. & Guse, A. H., 01.01.2013, In: FRONT IMMUNOL. 4, p. 259Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A mathematical model of T lymphocyte calcium dynamics derived from single transmembrane protein properties
Schmeitz, C., Hernandez-Vargas, E. A., Fliegert, R., Guse, A. H. & Meyer-Hermann, M., 01.01.2013, In: FRONT IMMUNOL. 4, p. 277Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Audio podcasts in practical courses in biochemistry - cost-efficient e-learning in a well-proven format from radio broadcasting
Münch-Harrach, D., Kothe, C. & Hampe, W., 01.01.2013, In: GMS Z Med Ausbild. 30, 4, p. Doc44Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health
Eissing, L., Scherer, T., Tödter, K., Knippschild, U., Greve, J. W., Buurman, W. A., Pinnschmidt, H. O., Rensen, S. S., Wolf, A. M., Bartelt, A., Heeren, J., Buettner, C. & Scheja, L., 01.01.2013, In: NAT COMMUN. 4, p. 1528Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells
Mulay, V., Wood, P., Manetsch, M., Darabi, M., Cairns, R., Hoque, M., Chan, K. C., Reverter, M., Alvarez-Guaita, A., Rye, K-A., Rentero, C., Heeren, J., Enrich, C. & Grewal, T., 01.01.2013, In: PLOS ONE. 8, 4, p. e62667Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Malignant H1299 tumour cells preferentially internalize iron-bound inositol hexakisphosphate
Helmis, C., Blechner, C., Lin, H., Schweizer, M., Mayr, G. W., Nielsen, P. & Windhorst, S., 01.01.2013, In: BIOSCIENCE REP. 33, 5Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NAADP signaling revisited
Guse, A. H., Wolf, I. & Fliegert, R., 01.01.2013, In: CURR TOP MED CHEM. 13, 23, p. 2978-90 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Hamburg selection procedure for dental students - introduction of the HAM-Nat as subject-specific test for study aptitude
Kothe, C., Hissbach, J. & Hampe, W., 01.01.2013, In: GMS Z Med Ausbild. 30, 4, p. Doc46Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TNFα-mediated liver destruction by Kupffer cells and Ly6Chi monocytes during Entamoeba histolytica infection
Helk, E., Bernin, H., Ernst, T., Ittrich, H., Jacobs, T., Heeren, J., Tacke, F., Tannich, E. & Lotter, H., 01.01.2013, In: PLOS PATHOG. 9, 1, p. e1003096Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain
Carlo, A-S., Gustafsen, C., Mastrobuoni, G., Nielsen, M. S., Burgert, T., Hartl, D., Rohe, M., Nykjaer, A., Herz, J., Heeren, J., Kempa, S., Petersen, C. M. & Willnow, T. E., 02.01.2013, In: J NEUROSCI. 33, 1, p. 358-70 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pharmacological characterization of 1-nitrosocyclohexyl acetate, a long-acting nitroxyl donor that shows vasorelaxant and antiaggregatory effects
Donzelli, S., Fischer, G., King, B. S., Niemann, C., DuMond, J. F., Heeren, J., Wieboldt, H., Baldus, S., Gerloff, C., Eschenhagen, T., Carrier, L., Böger, R. H. & Espey, M. G., 01.02.2013, In: J PHARMACOL EXP THER. 344, 2, p. 339-47 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
Kornfeld, J-W., Baitzel, C., Könner, A. C., Nicholls, H. T., Vogt, M. C., Herrmanns, K., Scheja, L., Haumaitre, C., Wolf, A. M., Knippschild, U., Seibler, J., Cereghini, S., Heeren, J., Stoffel, M. & Brüning, J. C., 07.02.2013, In: NATURE. 494, 7435, p. 111-5 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Novel aspects of brown adipose tissue biology
Heeren, J. & Münzberg, H., 01.03.2013, In: ENDOCRIN METAB CLIN. 42, 1, p. 89-107 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effects of adipocyte lipoprotein lipase on de novo lipogenesis and white adipose tissue browning
Bartelt, A., John, C., Cherradi, M. L., Niemeier, A., Tödter, K., Heeren, J. & Scheja, L., 01.05.2013, In: BBA-MOL CELL BIOL L. 1831, 5, p. 934-42 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
On health literacy and health outcomes: background, impact, and future directions
Rudd, R. E., Groene, O. R. & Navarro-Rubio, M. D., 21.05.2013, In: Revista de calidad asistencial : organo de la Sociedad Espanola de Calidad Asistencial. 28, 3, p. 188-92 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by β-adrenergic stimulation
Nebel, M., Schwoerer, A. P., Warszta, D., Siebrands, C. C., Limbrock, A-C., Swarbrick, J. M., Fliegert, R., Weber, K., Bruhn, S., Hohenegger, M., Geisler, A., Herich, L., Schlegel, S., Carrier, L., Eschenhagen, T., Potter, B. V. L., Ehmke, H. & Guse, A. H., 31.05.2013, In: J BIOL CHEM. 288, 22, p. 16017-30 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cycling assay for determining intracellular cyclic adp-ribose levels
Bruzzone, S. & Guse, A. H., 01.06.2013, In: Cold Spring Harbor protocols. 2013, 6, p. 564-8 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Measuring Ca2+ release evoked by cyclic adp-ribose
Guse, A. H., 01.06.2013, In: Cold Spring Harbor protocols. 2013, 6, p. 574-8 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Measuring CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) activity by reverse-phase HPLC
Kirchberger, T. & Guse, A. H., 01.06.2013, In: Cold Spring Harbor protocols. 2013, 6, p. 569-73 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Design and synthesis of cyclic ADP-4-thioribose as a stable equivalent of cyclic ADP-ribose, a calcium ion-mobilizing second messenger
Tsuzuki, T., Sakaguchi, N., Kudoh, T., Takano, S., Uehara, M., Murayama, T., Sakurai, T., Hashii, M., Higashida, H., Weber, K., Guse, A. H., Kameda, T., Hirokawa, T., Kumaki, Y., Potter, B. V. L., Fukuda, H., Arisawa, M. & Shuto, S., 24.06.2013, In: ANGEW CHEM INT EDIT. 52, 26, p. 6633-7 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Eisenquantifizierung mittels MRT bei Eisenüberladung
Schönnagel, B. P., Fischer, R., Nielsen, P., Grosse, R., Adam, G. & Yamamura, J., 01.07.2013, In: ROFO-FORTSCHR RONTG. 185, 7, p. 621-7 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
N-terminal tagging of two-pore channels interferes with NAADP action
Guse, A. H., 01.07.2013, In: BIOCHEM J. 453, 1, p. e1-2Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists
Moreau, C., Kirchberger, T., Swarbrick, J. M., Bartlett, S. J., Fliegert, R., Yorgan, T., Bauche, A., Harneit, A., Guse, A. H. & Potter, B. V. L., 27.12.2013, In: J MED CHEM. 56, 24, p. 10079-102 24 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Gadospin f-enhanced magnetic resonance imaging for diagnosis and monitoring of atherosclerosis: validation with transmission electron microscopy and x-ray fluorescence imaging in the apolipoprotein e-deficient mouse
Jung, C., Dučić, T., Reimer, R., Koziolek, E., Kording, F., Heine, M., Adam, G., Ittrich, H. & Kaul, M. G., 2014, In: MOL IMAGING. 13, p. 1-10 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adipose tissue browning and metabolic health
Bartelt, A. & Heeren, J., 01.01.2014, In: NAT REV ENDOCRINOL. 10, 1, p. 24-36 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cutting costs of multiple mini-interviews - changes in reliability and efficiency of the Hamburg medical school admission test between two applications
Hissbach, J. C., Sehner, S., Harendza, S. & Hampe, W., 01.01.2014, In: BMC MED EDUC. 14, p. 54Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selectins mediate small cell lung cancer systemic metastasis
Heidemann, F., Schildt, A., Schmid, K., Bruns, O. T., Riecken, K., Jung, C., Ittrich, H., Wicklein, D., Reimer, R., Fehse, B., Heeren, J., Lüers, G., Schumacher, U. & Heine, M., 01.01.2014, In: PLOS ONE. 9, 4, p. e92327Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The cell-type specific uptake of polymer-coated or micelle-embedded QDs and SPIOs does not provoke an acute pro-inflammatory response in the liver
Heine, M., Bartelt, A., Bruns, O. T., Bargheer, D., Giemsa, A., Freund, B., Scheja, L., Waurisch, C., Eychmüller, A., Reimer, R., Weller, H., Nielsen, P. & Heeren, J., 01.01.2014, In: BEILSTEIN J NANOTECH. 5, p. 1432-1440 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homozygosity for a partial deletion of apoprotein A-V signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant
Albers, K., Schlein, C., Wenner, K., Lohse, P., Bartelt, A., Heeren, J., Santer, R. & Merkel, M., 01.03.2014, In: ATHEROSCLEROSIS. 233, 1, p. 97-103 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intraperitoneal Injection Improves the Uptake of Nanoparticle-Labeled High-Density Lipoprotein to Atherosclerotic Plaques Compared With Intravenous Injection: A Multimodal Imaging Study in ApoE Knockout Mice
Jung, C., Kaul, M. G., Bruns, O. T., Dučić, T., Freund, B., Heine, M., Reimer, R., Meents, A., Salmen, S. C., Weller, H., Nielsen, P., Adam, G., Heeren, J. & Ittrich, H., 01.03.2014, In: CIRC-CARDIOVASC IMAG. 7, 2, p. 303-11 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism
Oehler, N., Volz, T., Bhadra, O. D., Kah, J., Allweiss, L., Giersch, K., Bierwolf, J., Riecken, K., Pollok, J. M., Lohse, A. W., Fehse, B., Petersen, J., Urban, S., Lütgehetmann, M., Heeren, J. & Dandri, M., 08.04.2014, In: HEPATOLOGY.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity
Bartelt, A., Beil, T., Müller, B., Koehne, T., Yorgan, T. A., Heine, M., Yilmaz, T., Ruether, W., Heeren, J., Schinke, T. & Niemeier, A., 01.05.2014, In: BONE. 62, p. 90-98 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cholesterol Regulates Syntaxin 6 Trafficking at trans-Golgi Network Endosomal Boundaries
Reverter, M., Rentero, C., Garcia-Melero, A., Hoque, M., Vilà de Muga, S., Alvarez-Guaita, A., Conway, J. R. W., Wood, P., Cairns, R., Lykopoulou, L., Grinberg, D., Vilageliu, L., Bosch, M., Heeren, J., Blasi, J., Timpson, P., Pol, A., Tebar, F., Murray, R. Z., Grewal, T. & Enrich, C., 08.05.2014, In: CELL REP. 7, 3, p. 883-897 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
GMA-Jahrestagung 2014 in Hamburg - Ankündigung
Hampe, W. & Kuhnigk, O., 15.05.2014, In: GMS Z Med Ausbild. 31, 2 Doc13, p. 1-4Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Transfer
Prediction of practical performance in preclinical laboratory courses - the return of wire bending for admission of dental students in Hamburg
Kothe, C., Hissbach, J. & Hampe, W., 15.05.2014, In: GMS Z Med Ausbild. 31, 2, p. Doc22Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dichloroacetate prevents restenosis in preclinical animal models of vessel injury
Deuse, T., Hua, X., Wang, D., Maegdefessel, L., Heeren, J., Scheja, L., Bolaños, J. P., Rakovic, A., Spin, J. M., Stubbendorff, M., Ikeno, F., Länger, F., Zeller, T., Schulte-Uentrop, L., Stoehr, A., Itagaki, R., Haddad, F., Eschenhagen, T., Blankenberg, S., Kiefmann, R., Reichenspurner, H., Velden, J., Klein, C., Yeung, A., Robbins, R. C., Tsao, P. S. & Schrepfer, S., 29.05.2014, In: NATURE. 509, 7502, p. 641-644 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Design, Synthesis, and Chemical and Biological Properties of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose
Tsuzuki, T., Takano, S., Sakaguchi, N., Kudoh, T., Murayama, T., Sakurai, T., Hashii, M., Higashida, H., Weber, K., Guse, A. H., Kameda, T., Hirokawa, T., Kumaki, Y., Arisawa, M., Potter, B. V. L. & Shuto, S., 01.06.2014, In: Messenger (Los Angel). 3, 1-2, p. 35-51 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice
Rinninger, F., Heine, M., Singaraja, R., Hayden, M., Brundert, M., Ramakrishnan, R. & Heeren, J., 01.09.2014, In: J LIPID RES. 55, 9, p. 1914-1924 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TGF-β-dependent induction of CD4⁺CD25⁺Foxp3⁺ Tregs by liver sinusoidal endothelial cells
Carambia, A., Freund, B., Schwinge, D., Heine, M., Laschtowitz, A., Huber, S., Wraith, D. C., Korn, T., Schramm, C., Lohse, A. W., Heeren, J. & Herkel, J., 01.09.2014, In: J HEPATOL. 61, 3, p. 594-9 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NAD derived second messengers: Role in spontaneous diastolic Ca(2+) transients
Warszta, D., Nebel, M., Fliegert, R. & Guse, A. H., 01.11.2014, In: DNA REPAIR. 23, p. 69-78Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Speed mentoring: establishing successful mentoring relationships
Kurré, J., Schweigert, E., Kulms, G. & Guse, A. H., 01.11.2014, In: MED EDUC. 48, 11, p. 1131Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism
Shin, A. C., Fasshauer, M., Filatova, N., Grundell, L. A., Zielinski, E., Zhou, J-Y., Scherer, T., Lindtner, C., White, P. J., Lapworth, A. L., Ilkayeva, O., Knippschild, U., Wolf, A. M., Scheja, L., Grove, K. L., Smith, R. D., Qian, W-J., Lynch, C. J., Newgard, C. B. & Buettner, C., 04.11.2014, In: CELL METAB. 20, 5, p. 898-909 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients
Porter, J. B., Walter, P. B., Neumayr, L. D., Evans, P., Bansal, S., Garbowski, M., Weyhmiller, M. G., Harmatz, P. R., Wood, J. C., Miller, J. L., Byrnes, C., Weiss, G., Seifert, M., Grosse, R., Grabowski, D., Schmidt, A., Fischer, R., Nielsen, P., Niemeyer, C. & Vichinsky, E., 12.2014, In: BRIT J HAEMATOL. 167, 5, p. 692-6 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiple mini-interviews: same concept, different approaches
Knorr, M. & Hissbach, J., 01.12.2014, In: MED EDUC. 48, 12, p. 1157-1175 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids
John, C., Werner, P., Worthmann, A., Wegner, K., Tödter, K., Scheja, L., Rohn, S., Heeren, J. & Fischer, M., 05.12.2014, In: J CHROMATOGR A. 1371, p. 184-195 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Synthesis of radioactively labelled CdSe/CdS/ZnS quantum dots for in vivo experiments
Stachowski, G. M., Bauer, C., Waurisch, C., Bargheer, D., Nielsen, P., Heeren, J., Hickey, S. G. & Eychmüller, A., 10.12.2014, In: BEILSTEIN J NANOTECH. 5, p. 2383-2387 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
A Modular Framework for Post-Processing and Analysis of Fluorescence Microscopy Image Sequences of Subcellular Calcium Dynamics
Schetelig, D., Wolf, I., Diercks, B-P., Fliegert, R., Guse, A., Schlaefer, A. & Werner, R., 2015, Bildverarbeitung für die Medizin 2015. Handels, H., Deserno, T. M., Meinzer, H-P. & Tolxdorff, T. (eds.). 1 ed. Berlin Heidelberg: Springer, p. 401-406 6 p. (Informatik Aktuell).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Annual conference of the GMA, Hamburg
Hampe, W. & Kuhnigk, O., 2015, In: GMS Z Med Ausbild. 32, 2, p. Doc16Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Transfer
Bestimmung des hypophysären Eisengehaltes mittels Multi-Echo-MRT-R2 Messungen
Berliner, C., Brehmer, M., Fischer, R., Grosse, R., Karul, M., Keller, S., Schönnagel, B., Wang, J., Adam, G. & Yamamura, J., 2015, In: ROFO-FORTSCHR RONTG. 187, S 01, p. WISS105_1Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
Berbée, J. F. P., Boon, M. R., Khedoe, P. P. S. J., Bartelt, A., Schlein, C., Worthmann, A., Kooijman, S., Hoeke, G., Mol, I. M., John, C., Jung, C., Vazirpanah, N., Brouwers, L. P. J., Gordts, P. L. S. M., Esko, J. D., Hiemstra, P. S., Havekes, L. M., Scheja, L., Heeren, J. & Rensen, P. C. N., 2015, In: NAT COMMUN. 6, p. 6356Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cooperative Feature Selection in Personalized Medicine
Zühlke, D., Grunst, G. & Röser, K., 2015, Decision Making: Uncertainty, Imperfection, Deliberation and Scalability. Guy, T. V., Kárný, M. & Wolpert, D. H. (eds.). 1 ed. Springer International Publishing, p. 119-144 26 p. (Studies in Computational Intelligence; vol. 538).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Determination of liver-specific r2 * of a highly monodisperse USPIO by (59) Fe iron core-labeling in mice at 3 T MRI
Raabe, N., Forberich, E., Freund, B., Bruns, O. T., Heine, M., Kaul, M. G., Tromsdorf, U., Herich, L., Nielsen, P., Reimer, R., Hohenberg, H., Weller, H., Schumacher, U., Adam, G. & Ittrich, H., 2015, In: CONTRAST MEDIA MOL I. 10, p. 153-62Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic Dissection of Tissue-Specific Apolipoprotein E Function for Hypercholesterolemia and Diet-Induced Obesity
Wagner, T., Bartelt, A., Schlein, C. & Heeren, J., 2015, In: PLOS ONE. 10, 12, e0145102.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Introduction of the HAM-Nat examination – applicants and students admitted to the Medical Faculty in 2012-2014.
Werwick, K., Winkler-Stuck, K., Hampe, W., Albrecht, P. & Robra, B-P., 2015, In: GMS Z Med Ausbild. 32, 5, p. Doc53Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The fate of a designed protein corona on nanoparticles in vitro and in vivo
Bargheer, D., Nielsen, J., Gébel, G., Heine, M., Salmen, S. C., Stauber, R., Weller, H., Heeren, J. & Nielsen, P., 06.01.2015, In: BEILSTEIN J NANOTECH. 6, p. 36-46 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The distribution and degradation of radiolabeled superparamagnetic iron oxide nanoparticles and quantum dots in mice
Bargheer, D., Giemsa, A., Freund, B., Heine, M., Waurisch, C., Stachowski, G. M., Hickey, S. G., Eychmüller, A., Heeren, J. & Nielsen, P., 09.01.2015, In: BEILSTEIN J NANOTECH. 6, p. 111-23 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice
Carambia, A., Freund, B., Schwinge, D., Bruns, O. T., Salmen, S. C., Ittrich, H., Reimer, R., Heine, M., Huber, S., Waurisch, C., Eychmüller, A., Wraith, D. C., Korn, T., Nielsen, P., Weller, H., Schramm, C., Lüth, S., Lohse, A. W., Heeren, J. & Herkel, J., 21.01.2015, In: J HEPATOL. 62, 6, p. 1349-1356Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Determining the association between adipokine expression in multiple tissues and phenotypic features of non-alcoholic fatty liver disease in obesity
Wolfs, M. G. M., Gruben, N., Rensen, S. S., Verdam, F. J., Greve, J. W., Driessen, A., Wijmenga, C., Buurman, W. A., Franke, L., Scheja, L., Koonen, D. P. Y., Shiri-Sverdlov, R., van Haeften, T. W., Hofker, M. H. & Fu, J., 02.2015, In: NUTR DIABETES. 5, p. Art. e146Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Arginine and NASH--do macrophages deliver the first hit?
Scheja, L. & Kluwe, J., 01.02.2015, In: J HEPATOL. 62, 2, p. 260-1 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Lrp1/LDL receptor play critical roles in mannose 6-phosphate-independent lysosomal enzyme targeting
Markmann, S., Thelen, M., Cornils, K., Schweizer, M., Brocke-Ahmadinejad, N., Willnow, T., Heeren, J., Gieselmann, V., Braulke, T. & Kollmann, K., 18.03.2015, In: TRAFFIC.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice
Baumeier, C., Kaiser, D., Heeren, J., Scheja, L., John, C., Weise, C., Eravci, M., Lagerpusch, M., Schulze, G., Joost, H-G., Schwenk, R. W. & Schürmann, A., 05.2015, In: Biochim Biophys Acta. 1851, 5, p. 566-76 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissue
Hoffmann, L. S., Etzrodt, J., Willkomm, L., Sanyal, A., Scheja, L., Fischer, A. W. C., Stasch, J-P., Bloch, W., Friebe, A., Heeren, J. & Pfeifer, A., 05.2015, In: NAT COMMUN. 6, p. Art. 7235Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation
Nebel, M., Zhang, B., Odoardi, F., Flügel, A., Potter, B. V. L. & Guse, A. H., 06.2015, In: Messenger (Los Angel). 4, 1, p. 104-111 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cidea improves the metabolic profile through expansion of adipose tissue
Abreu-Vieira, G., Fischer, A. W., Mattsson, C., de Jong, J. M. A., Shabalina, I. G., Rydén, M., Laurencikiene, J., Arner, P., Cannon, B., Nedergaard, J. & Petrovic, N., 06.2015, In: NAT COMMUN. 6, p. Art. 7433Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The trouble with validity: what is part of it and what is not?
Knorr, M. & Klusmann, D., 06.2015, In: MED EDUC. 49, 6, p. 550-2 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Prevalence of non-alcoholic fatty liver disease in four different weight related patient Groups: association with small bowel length and risk factors
Hillenbrand, A., Kiebler, B., Schwab, C., Scheja, L., Xu, P., Henne-Bruns, D., Wolf, A. M. & Knippschild, U., 03.07.2015, In: BMC RES NOTES. 8, p. 290Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The new InsP3Kinase inhibitor BIP-4 is competitive to InsP3 and blocks proliferation and adhesion of lung cancer cells
Schröder, D., Tödter, K., Gonzalez, B., Franco-Echevarría, E., Rohaly, G., Blechner, C., Lin, H., Mayr, G. W. & Windhorst, S., 15.07.2015, In: BIOCHEM PHARMACOL. 96, 2, p. 143-50 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Site-1 protease-activated formation of lysosomal targeting motifs is independent of the lipogenic transcription control
Klünder, S., Heeren, J., Markmann, S., Santer, R., Braulke, T. & Pohl, S., 08.2015, In: J LIPID RES. 56, 8, p. 1625-32 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Calcium mobilizing second messengers derived from NAD
Guse, A. H., 01.09.2015, In: BBA-PROTEINS PROTEOM. 1854, 9, p. 1132-1137Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Apolipoprotein E promotes lipid accumulation and differentiation in human adipocytes
Lasrich, D., Bartelt, A., Grewal, T. & Heeren, J., 10.09.2015, In: EXP CELL RES. 337, 1, p. 94-102 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Frontrunners of T cell activation: Initial, localized Ca2+ signals mediated by NAADP and the type 1 ryanodine receptor
Wolf, I. M. A., Diercks, B-P., Gattkowski, E., Czarniak, F., Kempski, J., Werner, R., Schetelig, D., Mittrücker, H-W., Schumacher, V., von Osten, M., Lodygin, D., Flügel, A., Fliegert, R. & Guse, A. H., 13.10.2015, In: SCI SIGNAL. 8, 398, p. Art. ra102 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure
Dijk, W., Heine, M., Vergnes, L., Boon, M. R., Schaart, G., Hesselink, M. K., Reue, K., van Marken Lichtenbelt, W. D., Olivecrona, G., Rensen, P. C., Heeren, J. & Kersten, S., 17.10.2015, In: ELIFE. 4Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diabetes prevalence in NZO females depends on estrogen action on liver fat content
Lubura, M., Hesse, D., Krämer, M., Hallahan, N., Schupp, M., Loeffelholz, C. V., Kriebel, J., Rudovich, N. N., Pfeiffer, A. F., John, C., Scheja, L., Heeren, J., Koliaki, C., Roden, M. & Schürmann, A., 15.12.2015, In: AM J PHYSIOL-ENDOC M. 309, 12, p. E968-E980Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Are Exam Questions Known in Advance? Using Local Dependence to Detect Cheating
Zimmermann, S., Klusmann, D. & Hampe, W., 2016, In: PLOS ONE. 11, 12, p. e0167545Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Attenuated viral hepatitis in Trem1-/- mice is associated with reduced inflammatory activity of neutrophils
Kozik, J-H., Trautmann, T., Carambia, A., Preti, M., Lütgehetmann, M., Krech, T., Wiegard, C., Heeren, J. & Herkel, J., 2016, In: SCI REP-UK. 6, p. 28556Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Entwicklung einer computerbasierten Schwierigkeitsabschätzung von Leseverstehensaufgaben
Zimmermann, S., 2016.Research output: Working paper › Working papers
Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
Chen, Y., Buyel, J. J., Hanssen, M. J. W., Siegel, F., Pan, R., Naumann, J., Schell, M., van der Lans, A., Schlein, C., Froehlich, H., Heeren, J., Virtanen, K. A., van Marken Lichtenbelt, W. & Pfeifer, A., 2016, In: NAT COMMUN. 7, p. 11420Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Health Literacy: Literature review for the German National Health Literacy Action Plan
Groene, O., 2016.Research output: Working paper › Research communication reports
Magnetic Particle / Magnetic Resonance Imaging: In-Vitro MPI-Guided Real Time Catheter Tracking and 4D Angioplasty Using a Road Map and Blood Pool Tracer Approach
Salamon, J., Hofmann, M., Jung, C., Kaul, M. G., Werner, F., Them, K., Reimer, R., Nielsen, P., Vom Scheidt, A., Adam, G., Knopp, T. & Ittrich, H., 2016, In: PLOS ONE. 11, 6, p. e0156899Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Resveratrol and Lifespan in Model Organisms
Pallauf, K., Rimbach, G., Rupp, P. M., Chin, D. & Wolf, I., 2016, In: CURR MED CHEM. 23, 41, p. 4641-4682Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effects of Mentoring Speed Dating as an Innovative Matching Tool in Undergraduate Medical Education: A Mixed Methods Study
Guse, J., Schweigert, E., Kulms, G., Heinen, I., Martens, C. & Guse, A., 09.02.2016, In: PLOS ONE. 11, 2, p. e0147444Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Leptin Raises Defended Body Temperature without Activating Thermogenesis
Fischer, A. W., Hoefig, C. S., Abreu-Vieira, G., de Jong, J. M. A., Petrovic, N., Mittag, J., Cannon, B. & Nedergaard, J., 23.02.2016, In: CELL REP. 14, 7, p. 1621-31 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dicer1-miR-328-Bace1 signalling controls brown adipose tissue differentiation and function
Oliverio, M., Schmidt, E., Mauer, J., Baitzel, C., Hansmeier, N., Khani, S., Konieczka, S., Pradas-Juni, M., Brodesser, S., Van, T-M., Bartsch, D., Brönneke, H. S., Heine, M., Hilpert, H., Tarcitano, E., Garinis, G. A., Frommolt, P., Heeren, J., Mori, M. A., Brüning, J. C. & Kornfeld, J-W., 03.2016, In: NAT CELL BIOL. 18, 3, p. 328-36 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation
Krott, L. M., Piscitelli, F., Heine, M., Borrino, S., Scheja, L., Silvestri, C., Heeren, J. & Di Marzo, V., 03.2016, In: J LIPID RES. 57, 3, p. 464-73 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative Activity Measurements of Brown Adipose Tissue at 7 T Magnetic Resonance Imaging After Application of Triglyceride-Rich Lipoprotein 59Fe-Superparamagnetic Iron Oxide Nanoparticle: Intravenous Versus Intraperitoneal Approach
Jung, C. S. L., Heine, M., Freund, B., Reimer, R., Koziolek, E. J., Kaul, M. G., Kording, F., Schumacher, U., Weller, H., Nielsen, P., Adam, G., Heeren, J. & Ittrich, H., 03.2016, In: INVEST RADIOL. 51, 3, p. 194-202 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues
Schlein, C., Talukdar, S., Heine, M., Fischer, A. W., Krott, L. M., Nilsson, S. K., Brenner, M. B., Heeren, J. & Scheja, L., 08.03.2016, In: CELL METAB. 23, 3, p. 441-53 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis
Schröder, T., Kucharczyk, D., Bär, F., Pagel, R., Derer, S., Jendrek, S. T., Sünderhauf, A., Brethack, A-K., Hirose, M., Möller, S., Künstner, A., Bischof, J., Weyers, I., Heeren, J., Koczan, D., Schmid, S. M., Divanovic, S., Giles, D. A., Adamski, J., Fellermann, K., Lehnert, H., Köhl, J., Ibrahim, S. & Sina, C., 04.2016, In: CELL METAB. 5, 4, p. 283-95 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Exploring the value and role of integrated supportive science courses in the reformed medical curriculum iMED: a mixed methods study
Eisenbarth, S., Tilling, T., Lueerss, E., Meyer, J., Sehner, S., Guse, A. & Guse, J., 29.04.2016, In: BMC MED EDUC. 16, p. 132Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Metabolic interplay between white, beige, brown adipocytes and the liver
Scheja, L. & Heeren, J., 05.2016, In: J HEPATOL. 64, 5, p. 1176-86 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Basic Principles of Science in Medical Education - Development and Implementation of a Two Week Introductory Track
Vonneilich, N., Dubben, H-H., Kriston, L., Guse, A. H. & von dem Knesebeck, O., 01.05.2016, In: Creat Educ. 7, 6, p. 831-837Research output: SCORING: Contribution to journal › SCORING: Journal article › Education › peer-review
In vivo degeneration and the fate of inorganic nanoparticles
Feliu, N., Docter, D., Heine, M., Del Pino, P., Ashraf, S., Kolosnjaj-Tabi, J., Macchiarini, P., Nielsen, P., Alloyeau, D., Gazeau, F., Stauber, R. H. & Parak, W. J., 03.05.2016, In: CHEM SENSES. 45, 9, p. 2440-57 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Utilizing immunoaffinity chromatography (IAC) cross-reactivity in GC-MS/MS exemplified at the measurement of prostaglandin E1 in human plasma using prostaglandin E2-specific IAC columns
Tsikas, D., Suchy, M-T., Tödter, K., Heeren, J. & Scheja, L., 15.05.2016, In: J CHROMATOGR B. 1021, p. 101-7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review