Research ExplorerResearch UnitsDepartment of Biochemistry and Molecular Cell Biology Publications

Department of Biochemistry and Molecular Cell Biology

301 - 350 out of 580Page size: 50

Publications

  1. 2015

  2. ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure

    Dijk, W., Heine, M., Vergnes, L., Boon, M. R., Schaart, G., Hesselink, M. K., Reue, K., van Marken Lichtenbelt, W. D., Olivecrona, G., Rensen, P. C., Heeren, J. & Kersten, S., 17.10.2015, In: ELIFE. 4

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Frontrunners of T cell activation: Initial, localized Ca2+ signals mediated by NAADP and the type 1 ryanodine receptor

    Wolf, I. M. A., Diercks, B-P., Gattkowski, E., Czarniak, F., Kempski, J., Werner, R., Schetelig, D., Mittrücker, H-W., Schumacher, V., von Osten, M., Lodygin, D., Flügel, A., Fliegert, R. & Guse, A. H., 13.10.2015, In: SCI SIGNAL. 8, 398, p. Art. ra102 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Apolipoprotein E promotes lipid accumulation and differentiation in human adipocytes

    Lasrich, D., Bartelt, A., Grewal, T. & Heeren, J., 10.09.2015, In: EXP CELL RES. 337, 1, p. 94-102 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. Calcium mobilizing second messengers derived from NAD

    Guse, A. H., 01.09.2015, In: BBA-PROTEINS PROTEOM. 1854, 9, p. 1132-1137

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Site-1 protease-activated formation of lysosomal targeting motifs is independent of the lipogenic transcription control

    Klünder, S., Heeren, J., Markmann, S., Santer, R., Braulke, T. & Pohl, S., 08.2015, In: J LIPID RES. 56, 8, p. 1625-32 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. The new InsP3Kinase inhibitor BIP-4 is competitive to InsP3 and blocks proliferation and adhesion of lung cancer cells

    Schröder, D., Tödter, K., Gonzalez, B., Franco-Echevarría, E., Rohaly, G., Blechner, C., Lin, H., Mayr, G. W. & Windhorst, S., 15.07.2015, In: BIOCHEM PHARMACOL. 96, 2, p. 143-50 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Prevalence of non-alcoholic fatty liver disease in four different weight related patient Groups: association with small bowel length and risk factors

    Hillenbrand, A., Kiebler, B., Schwab, C., Scheja, L., Xu, P., Henne-Bruns, D., Wolf, A. M. & Knippschild, U., 03.07.2015, In: BMC RES NOTES. 8, p. 290

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation

    Nebel, M., Zhang, B., Odoardi, F., Flügel, A., Potter, B. V. L. & Guse, A. H., 06.2015, In: Messenger (Los Angel). 4, 1, p. 104-111 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Cidea improves the metabolic profile through expansion of adipose tissue

    Abreu-Vieira, G., Fischer, A. W., Mattsson, C., de Jong, J. M. A., Shabalina, I. G., Rydén, M., Laurencikiene, J., Arner, P., Cannon, B., Nedergaard, J. & Petrovic, N., 06.2015, In: NAT COMMUN. 6, p. Art. 7433

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. The trouble with validity: what is part of it and what is not?

    Knorr, M. & Klusmann, D., 06.2015, In: MED EDUC. 49, 6, p. 550-2 3 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  12. Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice

    Baumeier, C., Kaiser, D., Heeren, J., Scheja, L., John, C., Weise, C., Eravci, M., Lagerpusch, M., Schulze, G., Joost, H-G., Schwenk, R. W. & Schürmann, A., 05.2015, In: Biochim Biophys Acta. 1851, 5, p. 566-76 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissue

    Hoffmann, L. S., Etzrodt, J., Willkomm, L., Sanyal, A., Scheja, L., Fischer, A. W. C., Stasch, J-P., Bloch, W., Friebe, A., Heeren, J. & Pfeifer, A., 05.2015, In: NAT COMMUN. 6, p. Art. 7235

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Lrp1/LDL receptor play critical roles in mannose 6-phosphate-independent lysosomal enzyme targeting

    Markmann, S., Thelen, M., Cornils, K., Schweizer, M., Brocke-Ahmadinejad, N., Willnow, T., Heeren, J., Gieselmann, V., Braulke, T. & Kollmann, K., 18.03.2015, In: TRAFFIC.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Arginine and NASH--do macrophages deliver the first hit?

    Scheja, L. & Kluwe, J., 01.02.2015, In: J HEPATOL. 62, 2, p. 260-1 2 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  16. Determining the association between adipokine expression in multiple tissues and phenotypic features of non-alcoholic fatty liver disease in obesity

    Wolfs, M. G. M., Gruben, N., Rensen, S. S., Verdam, F. J., Greve, J. W., Driessen, A., Wijmenga, C., Buurman, W. A., Franke, L., Scheja, L., Koonen, D. P. Y., Shiri-Sverdlov, R., van Haeften, T. W., Hofker, M. H. & Fu, J., 02.2015, In: NUTR DIABETES. 5, p. Art. e146

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice

    Carambia, A., Freund, B., Schwinge, D., Bruns, O. T., Salmen, S. C., Ittrich, H., Reimer, R., Heine, M., Huber, S., Waurisch, C., Eychmüller, A., Wraith, D. C., Korn, T., Nielsen, P., Weller, H., Schramm, C., Lüth, S., Lohse, A. W., Heeren, J. & Herkel, J., 21.01.2015, In: J HEPATOL. 62, 6, p. 1349-1356

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. The distribution and degradation of radiolabeled superparamagnetic iron oxide nanoparticles and quantum dots in mice

    Bargheer, D., Giemsa, A., Freund, B., Heine, M., Waurisch, C., Stachowski, G. M., Hickey, S. G., Eychmüller, A., Heeren, J. & Nielsen, P., 09.01.2015, In: BEILSTEIN J NANOTECH. 6, p. 111-23 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. The fate of a designed protein corona on nanoparticles in vitro and in vivo

    Bargheer, D., Nielsen, J., Gébel, G., Heine, M., Salmen, S. C., Stauber, R., Weller, H., Heeren, J. & Nielsen, P., 06.01.2015, In: BEILSTEIN J NANOTECH. 6, p. 36-46 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. A Modular Framework for Post-Processing and Analysis of Fluorescence Microscopy Image Sequences of Subcellular Calcium Dynamics

    Schetelig, D., Wolf, I., Diercks, B-P., Fliegert, R., Guse, A., Schlaefer, A. & Werner, R., 2015, Bildverarbeitung für die Medizin 2015. Handels, H., Deserno, T. M., Meinzer, H-P. & Tolxdorff, T. (eds.). 1 ed. Berlin Heidelberg: Springer, p. 401-406 6 p. (Informatik Aktuell).

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review

  21. Annual conference of the GMA, Hamburg

    Hampe, W. & Kuhnigk, O., 2015, In: GMS Z Med Ausbild. 32, 2, p. Doc16

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Transfer

  22. Bestimmung des hypophysären Eisengehaltes mittels Multi-Echo-MRT-R2 Messungen

    Berliner, C., Brehmer, M., Fischer, R., Grosse, R., Karul, M., Keller, S., Schönnagel, B., Wang, J., Adam, G. & Yamamura, J., 2015, In: ROFO-FORTSCHR RONTG. 187, S 01, p. WISS105_1

    Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review

  23. Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

    Berbée, J. F. P., Boon, M. R., Khedoe, P. P. S. J., Bartelt, A., Schlein, C., Worthmann, A., Kooijman, S., Hoeke, G., Mol, I. M., John, C., Jung, C., Vazirpanah, N., Brouwers, L. P. J., Gordts, P. L. S. M., Esko, J. D., Hiemstra, P. S., Havekes, L. M., Scheja, L., Heeren, J. & Rensen, P. C. N., 2015, In: NAT COMMUN. 6, p. 6356

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Cooperative Feature Selection in Personalized Medicine

    Zühlke, D., Grunst, G. & Röser, K., 2015, Decision Making: Uncertainty, Imperfection, Deliberation and Scalability. Guy, T. V., Kárný, M. & Wolpert, D. H. (eds.). 1 ed. Springer International Publishing, p. 119-144 26 p. (Studies in Computational Intelligence; vol. 538).

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review

  25. Determination of liver-specific r2 * of a highly monodisperse USPIO by (59) Fe iron core-labeling in mice at 3 T MRI

    Raabe, N., Forberich, E., Freund, B., Bruns, O. T., Heine, M., Kaul, M. G., Tromsdorf, U., Herich, L., Nielsen, P., Reimer, R., Hohenberg, H., Weller, H., Schumacher, U., Adam, G. & Ittrich, H., 2015, In: CONTRAST MEDIA MOL I. 10, p. 153-62

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Genetic Dissection of Tissue-Specific Apolipoprotein E Function for Hypercholesterolemia and Diet-Induced Obesity

    Wagner, T., Bartelt, A., Schlein, C. & Heeren, J., 2015, In: PLOS ONE. 10, 12, e0145102.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Introduction of the HAM-Nat examination – applicants and students admitted to the Medical Faculty in 2012-2014.

    Werwick, K., Winkler-Stuck, K., Hampe, W., Albrecht, P. & Robra, B-P., 2015, In: GMS Z Med Ausbild. 32, 5, p. Doc53

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. 2014

  29. Synthesis of radioactively labelled CdSe/CdS/ZnS quantum dots for in vivo experiments

    Stachowski, G. M., Bauer, C., Waurisch, C., Bargheer, D., Nielsen, P., Heeren, J., Hickey, S. G. & Eychmüller, A., 10.12.2014, In: BEILSTEIN J NANOTECH. 5, p. 2383-2387 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids

    John, C., Werner, P., Worthmann, A., Wegner, K., Tödter, K., Scheja, L., Rohn, S., Heeren, J. & Fischer, M., 05.12.2014, In: J CHROMATOGR A. 1371, p. 184-195 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Multiple mini-interviews: same concept, different approaches

    Knorr, M. & Hissbach, J., 01.12.2014, In: MED EDUC. 48, 12, p. 1157-1175 19 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients

    Porter, J. B., Walter, P. B., Neumayr, L. D., Evans, P., Bansal, S., Garbowski, M., Weyhmiller, M. G., Harmatz, P. R., Wood, J. C., Miller, J. L., Byrnes, C., Weiss, G., Seifert, M., Grosse, R., Grabowski, D., Schmidt, A., Fischer, R., Nielsen, P., Niemeyer, C. & Vichinsky, E., 12.2014, In: BRIT J HAEMATOL. 167, 5, p. 692-6 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism

    Shin, A. C., Fasshauer, M., Filatova, N., Grundell, L. A., Zielinski, E., Zhou, J-Y., Scherer, T., Lindtner, C., White, P. J., Lapworth, A. L., Ilkayeva, O., Knippschild, U., Wolf, A. M., Scheja, L., Grove, K. L., Smith, R. D., Qian, W-J., Lynch, C. J., Newgard, C. B. & Buettner, C., 04.11.2014, In: CELL METAB. 20, 5, p. 898-909 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. NAD derived second messengers: Role in spontaneous diastolic Ca(2+) transients

    Warszta, D., Nebel, M., Fliegert, R. & Guse, A. H., 01.11.2014, In: DNA REPAIR. 23, p. 69-78

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Speed mentoring: establishing successful mentoring relationships

    Kurré, J., Schweigert, E., Kulms, G. & Guse, A. H., 01.11.2014, In: MED EDUC. 48, 11, p. 1131

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  36. High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice

    Rinninger, F., Heine, M., Singaraja, R., Hayden, M., Brundert, M., Ramakrishnan, R. & Heeren, J., 01.09.2014, In: J LIPID RES. 55, 9, p. 1914-1924 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. TGF-β-dependent induction of CD4⁺CD25⁺Foxp3⁺ Tregs by liver sinusoidal endothelial cells

    Carambia, A., Freund, B., Schwinge, D., Heine, M., Laschtowitz, A., Huber, S., Wraith, D. C., Korn, T., Schramm, C., Lohse, A. W., Heeren, J. & Herkel, J., 01.09.2014, In: J HEPATOL. 61, 3, p. 594-9 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Design, Synthesis, and Chemical and Biological Properties of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose

    Tsuzuki, T., Takano, S., Sakaguchi, N., Kudoh, T., Murayama, T., Sakurai, T., Hashii, M., Higashida, H., Weber, K., Guse, A. H., Kameda, T., Hirokawa, T., Kumaki, Y., Arisawa, M., Potter, B. V. L. & Shuto, S., 01.06.2014, In: Messenger (Los Angel). 3, 1-2, p. 35-51 17 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Dichloroacetate prevents restenosis in preclinical animal models of vessel injury

    Deuse, T., Hua, X., Wang, D., Maegdefessel, L., Heeren, J., Scheja, L., Bolaños, J. P., Rakovic, A., Spin, J. M., Stubbendorff, M., Ikeno, F., Länger, F., Zeller, T., Schulte-Uentrop, L., Stoehr, A., Itagaki, R., Haddad, F., Eschenhagen, T., Blankenberg, S., Kiefmann, R., Reichenspurner, H., Velden, J., Klein, C., Yeung, A., Robbins, R. C., Tsao, P. S. & Schrepfer, S., 29.05.2014, In: NATURE. 509, 7502, p. 641-644 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. GMA-Jahrestagung 2014 in Hamburg - Ankündigung

    Hampe, W. & Kuhnigk, O., 15.05.2014, In: GMS Z Med Ausbild. 31, 2 Doc13, p. 1-4

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Transfer

  41. Prediction of practical performance in preclinical laboratory courses - the return of wire bending for admission of dental students in Hamburg

    Kothe, C., Hissbach, J. & Hampe, W., 15.05.2014, In: GMS Z Med Ausbild. 31, 2, p. Doc22

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Cholesterol Regulates Syntaxin 6 Trafficking at trans-Golgi Network Endosomal Boundaries

    Reverter, M., Rentero, C., Garcia-Melero, A., Hoque, M., Vilà de Muga, S., Alvarez-Guaita, A., Conway, J. R. W., Wood, P., Cairns, R., Lykopoulou, L., Grinberg, D., Vilageliu, L., Bosch, M., Heeren, J., Blasi, J., Timpson, P., Pol, A., Tebar, F., Murray, R. Z., Grewal, T. & Enrich, C., 08.05.2014, In: CELL REP. 7, 3, p. 883-897 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity

    Bartelt, A., Beil, T., Müller, B., Koehne, T., Yorgan, T. A., Heine, M., Yilmaz, T., Ruether, W., Heeren, J., Schinke, T. & Niemeier, A., 01.05.2014, In: BONE. 62, p. 90-98 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism

    Oehler, N., Volz, T., Bhadra, O. D., Kah, J., Allweiss, L., Giersch, K., Bierwolf, J., Riecken, K., Pollok, J. M., Lohse, A. W., Fehse, B., Petersen, J., Urban, S., Lütgehetmann, M., Heeren, J. & Dandri, M., 08.04.2014, In: HEPATOLOGY.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Homozygosity for a partial deletion of apoprotein A-V signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant

    Albers, K., Schlein, C., Wenner, K., Lohse, P., Bartelt, A., Heeren, J., Santer, R. & Merkel, M., 01.03.2014, In: ATHEROSCLEROSIS. 233, 1, p. 97-103 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. Intraperitoneal Injection Improves the Uptake of Nanoparticle-Labeled High-Density Lipoprotein to Atherosclerotic Plaques Compared With Intravenous Injection: A Multimodal Imaging Study in ApoE Knockout Mice

    Jung, C., Kaul, M. G., Bruns, O. T., Dučić, T., Freund, B., Heine, M., Reimer, R., Meents, A., Salmen, S. C., Weller, H., Nielsen, P., Adam, G., Heeren, J. & Ittrich, H., 01.03.2014, In: CIRC-CARDIOVASC IMAG. 7, 2, p. 303-11 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Adipose tissue browning and metabolic health

    Bartelt, A. & Heeren, J., 01.01.2014, In: NAT REV ENDOCRINOL. 10, 1, p. 24-36 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Cutting costs of multiple mini-interviews - changes in reliability and efficiency of the Hamburg medical school admission test between two applications

    Hissbach, J. C., Sehner, S., Harendza, S. & Hampe, W., 01.01.2014, In: BMC MED EDUC. 14, p. 54

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. Selectins mediate small cell lung cancer systemic metastasis

    Heidemann, F., Schildt, A., Schmid, K., Bruns, O. T., Riecken, K., Jung, C., Ittrich, H., Wicklein, D., Reimer, R., Fehse, B., Heeren, J., Lüers, G., Schumacher, U. & Heine, M., 01.01.2014, In: PLOS ONE. 9, 4, p. e92327

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. The cell-type specific uptake of polymer-coated or micelle-embedded QDs and SPIOs does not provoke an acute pro-inflammatory response in the liver

    Heine, M., Bartelt, A., Bruns, O. T., Bargheer, D., Giemsa, A., Freund, B., Scheja, L., Waurisch, C., Eychmüller, A., Reimer, R., Weller, H., Nielsen, P. & Heeren, J., 01.01.2014, In: BEILSTEIN J NANOTECH. 5, p. 1432-1440 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Gadospin f-enhanced magnetic resonance imaging for diagnosis and monitoring of atherosclerosis: validation with transmission electron microscopy and x-ray fluorescence imaging in the apolipoprotein e-deficient mouse

    Jung, C., Dučić, T., Reimer, R., Koziolek, E., Kording, F., Heine, M., Adam, G., Ittrich, H. & Kaul, M. G., 2014, In: MOL IMAGING. 13, p. 1-10 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. 2013

  53. Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists

    Moreau, C., Kirchberger, T., Swarbrick, J. M., Bartlett, S. J., Fliegert, R., Yorgan, T., Bauche, A., Harneit, A., Guse, A. H. & Potter, B. V. L., 27.12.2013, In: J MED CHEM. 56, 24, p. 10079-102 24 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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