Research ExplorerResearch UnitsInstitute of Experimental Pharmacology and Toxicology Publications

Institute of Experimental Pharmacology and Toxicology

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Publications

  1. 2004

  2. Suppression of paroxysmal atrial tachyarrhythmias--results of the SOPAT trial.

    Patten-Hamel, M., Maas, R., Bauer, P., Lüderitz, B., Sonntag, F., Dluzniewski, M., Hatala, R., Opolski, G., Müller, H-W. & Meinertz, T., 2004, In: EUR HEART J. 25, 16, p. 1395-1404 16.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Urinary 8-iso-prostaglandin F2alpha as a risk marker in patients with coronary heart disease: a matched case-control study.

    Schwedhelm, E., Bartling, A., Lenzen, H., Tsikas, D., Maas, R., Brümmer, J., Gutzki, F-M., Berger, J., Frölich, J. C. & Böger, R. H., 2004, In: CIRCULATION. 109, 7, p. 843-848 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. 2003

  5. 24-h Langendorff-perfused neonatal rat heart used to study the impact of adenoviral gene transfer.

    Wiechert, S., El-Armouche, A., Rau, T., Zimmermann, W-H. & Eschenhagen, T., 2003, In: AM J PHYSIOL-HEART C. 285, 2, p. 907-914 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Accurate quantification of basal plasma levels of 3-nitrotyrosine and 3-nitrotyrosinoalbumin by gas chromatography-tandem mass spectrometry.

    Tsikas, D., Schwedhelm, E., Stutzer, F. K., Gutzki, F. M., Iris, R., Mehls, C. & Frölich, J. C., 2003, In: J CHROMATOGR B. 784, 1, p. 77-90 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Aceclofenac spares cyclooxygenase 1 as a result of limited but sustained biotransformation to diclofenac.

    Hinz, B., Rau, T., Auge, D., Werner, U., Ramer, R., Rietbrock, S. & Brune, K., 2003, In: CLIN PHARMACOL THER. 74, 3, p. 222-235 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. A crown venting technique for the cementation of implant-supported crowns.

    Schwedhelm, E., Lepe, X. & Aw, T. C., 2003, In: J PROSTHET DENT. 89, 1, p. 89-90 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins.

    Sydow, K., Schwedhelm, E., Arakawa, N., Bode-Böger, S. M., Tsikas, D., Hornig, B., Frölich, J. C. & Böger, R. H., 2003, In: CARDIOVASC RES. 57, 1, p. 244-252 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Antihypertensive therapy: special focus on drug interactions.

    Maas, R. & Böger, R. H., 2003, In: EXPERT OPIN DRUG SAF. 2, 6, p. 549-579 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Application of gas chromatography-mass spectrometry for analysis of isoprostanes: their role in cardiovascular disease.

    Schwedhelm, E. & Böger, R. H., 2003, In: CLIN CHEM LAB MED. 41, 12, p. 1552-1561 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Beta-adrenergic stimulation induces cardiac ankyrin repeat protein expression: involvement of protein kinase A and calmodulin-dependent kinase.

    Zolk, O., Marx, M., Jäckel, E., El-Armouche, A. & Eschenhagen, T., 2003, In: CARDIOVASC RES. 59, 3, p. 563-572 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Celecoxib inhibits metabolism of cytochrome P450 2D6 substrate metoprolol in humans.

    Werner, U., Werner, D., Rau, T., Fromm, M. F., Hinz, B. & Brune, K., 2003, In: CLIN PHARMACOL THER. 74, 2, p. 130-137 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. [Citalopram]

    El-Armouche, A., Zolk, O. & Eschenhagen, T., 2003, In: DEUT MED WOCHENSCHR. 128, 43, p. 2253-2256 43.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Clinical pharmacokinetics of antioxidants and their impact on systemic oxidative stress.

    Schwedhelm, E., Maas, R., Troost, R. & Böger, R. H., 2003, In: CLIN PHARMACOKINET. 42, 5, p. 437-459 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Diagnostic yield of external electrocardiographic loop recorders in patients with recurrent syncope and negative tilt table test.

    Schuchert, A., Maas, R., Kretzschmar, C., Behrens, G., Kratzmann, I. & Meinertz, T., 2003, In: PACE. 26, 9, p. 1837-1840 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Divergence in urinary 8-iso-PGF(2alpha) (iPF(2alpha)-III, 15-F(2t)-IsoP) levels from gas chromatography-tandem mass spectrometry quantification after thin-layer chromatography and immunoaffinity column chromatography reveals heterogeneity of 8-iso-PGF(2alpha). Possible methodological, mechanistic and clinical implications.

    Tsikas, D., Schwedhelm, E., Suchy, M. T., Niemann, J., Gutzki, F. M., Erpenbeck, V. J., Hohlfeld, J. M., Surdacki, A. & Frölich, J. C., 2003, In: J CHROMATOGR B. 794, 2, p. 237-255 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Evidence for protein phosphatase inhibitor-1 playing an amplifier role in beta-adrenergic signaling in cardiac myocytes.

    El-Armouche, A., Rau, T., Zolk, O., Ditz, D., Pamminger, T., Zimmermann, W-H., Jäckel, E., Harding, S. E., Boknik, P., Neumann, J. & Eschenhagen, T., 2003, In: FASEB J. 17, 3, p. 437-439 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Inhibitory G-proteins and their role in desensitization of the adenylyl cyclase pathway in heart failure.

    El-Armouche, A., Zolk, O., Rau, T. & Eschenhagen, T., 2003, In: CARDIOVASC RES. 60, 3, p. 478-487 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Old and new cardiovascular risk factors: from unresolved issues to new opportunities.

    Maas, R. & Böger, R. H., 2003, In: ATHEROSCLEROSIS PLUS. 4, 4, p. 5-17 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Overexpression of wild-type Galpha(i)-2 suppresses beta-adrenergic signaling in cardiac myocytes.

    Rau, T., Nose, M., Remmers, U., Weil, J., Weissmüller, A., Davia, K., Harding, S., Peppel, K., Koch, W. J. & Eschenhagen, T., 2003, In: FASEB J. 17, 3, p. 523-525 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Simultaneous determination of aceclofenac and three of its metabolites in human plasma by high-performance liquid chromatography.

    Hinz, B., Auge, D., Rau, T., Rietbrock, S., Brune, K. & Werner, U., 2003, In: BIOMED CHROMATOGR. 17, 4, p. 268-275 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Syncope, driving recommendations, and clinical reality: survey of patients.

    Maas, R., Ventura, R., Kretzschmar, C., Aydin, M. A. & Schuchert, A., 2003, In: BMJ-BRIT MED J. 326, 7379, p. 21 7379.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. The mutagenic potentials of tap water samples in Shanghai.

    Shen, L., Wu, J-Y., Lin, G-F., Shen, J-H., Westendorf, J. & Huehnerfuss, H., 2003, In: CHEMOSPHERE. 52, 9, p. 1641-1646 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. 2002

  26. Activation of the cardiac endothelin system in left ventricular hypertrophy before onset of heart failure in TG(mREN2)27 rats.

    Zolk, O., Quattek, J., Seeland, U., El-Armouche, A., Eschenhagen, T. & Böhm, M., 2002, In: CARDIOVASC RES. 53, 2, p. 363-371 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. A randomized and controlled pilot trial of beta-blockers for the treatment of recurrent syncope in patients with a positive or negative response to head-up tilt test.

    Ventura, R., Maas, R., Zeidler, D., Schoder, V., Nienaber, C. A., Schuchert, A. & Meinertz, T., 2002, In: PACE. 25, 5, p. 816-821 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Asymmetric dimethylarginine, C-reactive protein, and carotid intima-media thickness in end-stage renal disease.

    Zoccali, C., Benedetto, F. A., Maas, R., Mallamaci, F., Tripepi, G., Malatino, L. S. & Böger, R., 2002, In: J AM SOC NEPHROL. 13, 2, p. 490-496 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. [Drug prescription studies. Goals and results]

    Köhler, G. I. & Maas, R., 2002, In: INTERNIST. 43, 4, p. 511-515 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Effect of the CYP2D6 genotype on metoprolol metabolism persists during long-term treatment.

    Rau, T., Roland, H., Bergmann, K., Wuttke, H., Werner, U., Feifel, N. & Eschenhagen, T., 2002, In: PHARMACOGENETICS. 12, 6, p. 465-472 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Increased frequency of cytochrome P450 2D6 poor metabolizers among patients with metoprolol-associated adverse effects.

    Wuttke, H., Rau, T., Roland, H., Bergmann, K., Böhm, M., Weil, J., Werner, D. & Eschenhagen, T., 2002, In: CLIN PHARMACOL THER. 72, 4, p. 429-437 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients.

    Zoccali, C., Mallamaci, F., Maas, R., Benedetto, F. A., Tripepi, G., Malatino, L. S., Cataliotti, A., Bellanuova, I. & Böger, R., 2002, In: KIDNEY INT. 62, 1, p. 339-345 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Methodological considerations on the detection of 3-nitrotyrosine in the cardiovascular system.

    Tsikas, D., Schwedhelm, E. & Frölich, J. C., 2002, In: CIRC RES. 90, 6, p. 70 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Physiological antagonism between ventricular beta 1-adrenoceptors and alpha 1-adrenoceptors but no evidence for beta 2- and beta 3-adrenoceptor function in murine heart.

    Heubach, J. F., Rau, T., Eschenhagen, T., Ravens, U. & Kaumann, A. J., 2002, In: BRIT J PHARMACOL. 136, 2, p. 217-229 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Polyetheretherketone--cytotoxicity and mutagenicity in vitro.

    Katzer, A., Marquardt, H., Westendorf, J., Wening, J. V. & von Foerster, G., 2002, In: BIOMATERIALS. 23, 8, p. 1749-1759 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. The pathophysiology of erectile dysfunction related to endothelial dysfunction and mediators of vascular function.

    Maas, R., Schwedhelm, E., Albsmeier, J. & Böger, R. H., 2002, In: VASC MED. 7, 3, p. 213-225 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. 2001

  38. Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogens.

    Gutendorf, B. & Westendorf, J., 2001, In: TOXICOLOGY. 166, 1-2, p. 79-89 1-2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Constitutive expression and localization of COX-1 and COX-2 in rabbit iris and ciliary body.

    Damm, J., Rau, T., Maihöfner, C., Pahl, A. & Brune, K., 2001, In: EXP EYE RES. 72, 6, p. 611-621 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. [Drug interactions in the practice. Which combinations are taboo?]

    Zolk, O., El-Armouche, A. & Eschenhagen, T., 2001, In: MMW Fortschr Med. 143, 51-52, p. 24-32 51-52.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. [Emergencies in the practice. Hazards of "mix syringe"]

    Münzel, F., Eschenhagen, T., Rau, T. & Zolk, O., 2001, In: MMW Fortschr Med. 143, 44, p. 44-47 44.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Fiber type-specific expression of major proteolytic systems in fast- to slow-transforming rabbit muscle.

    Sultan, K., Dittrich, B. T., Leisner, E., Paul, N. & Pette, D., 2001, In: AM J PHYSIOL-CELL PH. 280, 2, p. 239-247 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Fiber-type transitions and satellite cell activation in low-frequency-stimulated muscles of young and aging rats.

    Putman, C. T., Sultan, K., Wassmer, T., Bamford, J. A., Skorjanc, D. & Pette, D., 2001, In: J GERONTOL A-BIOL. 56, 12, p. 510-519 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Flurbiprofen enantiomers inhibit inducible nitric oxide synthase expression in RAW 264.7 macrophages.

    Hinz, B., Brune, K., Rau, T. & Pahl, A., 2001, In: PHARM RES-DORDR. 18, 2, p. 151-156 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. In vitro suppression of thymocyte apoptosis by metal-rich complex environmental mixtures: potential role of zinc and cadmium excess.

    Chukhlovi, A. B., Tokalov, S. V., Yagunov, A. S., Westendorf, J., Reincke, H. & Karbe, L., 2001, In: SCI TOTAL ENVIRON. 281, 1-3, p. 153-163 1-3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. Muscle LIM protein is upregulated in fast skeletal muscle during transition toward slower phenotypes.

    Willmann, R., Kusch, J., Sultan, K., Schneider, A. G. & Pette, D., 2001, In: AM J PHYSIOL-CELL PH. 280, 2, p. 273-279 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Prinzmetal angina documented by transtelephonic electrocardiographic monitoring.

    Maas, R., Brockhoff, C., Patten-Hamel, M. & Meinertz, T., 2001, In: CIRCULATION. 103, 22, p. 2766 22.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Psychiatric conditions in patients with recurrent unexplained syncope.

    Ventura, R., Maas, R., Rüppel, R., Stuhr, U., Schuchert, A., Meinertz, T. & Nienaber, C. A., 2001, In: EUROPACE. 3, 4, p. 311-316 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. Toxicological profile of pollutants in surface water from an area in Taihu Lake, Yangtze Delta.

    Shen, J. H., Gutendorf, B., Vahl, H. H., Shen, L. & Westendorf, J., 2001, In: TOXICOLOGY. 166, 1-2, p. 71-78 1-2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. 2000

  51. Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift.

    Doetze, A., Satoguina, J., Burchard, G., Rau, T., Löliger, C., Fleischer, B. & Hoerauf, A., 2000, In: INT IMMUNOL. 12, 5, p. 623-630 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. Calpain activity in fast, slow, transforming, and regenerating skeletal muscles of rat.

    Sultan, K., Dittrich, B. T. & Pette, D., 2000, In: AM J PHYSIOL-CELL PH. 279, 3, p. 639-647 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. Cell transformation and genotoxicity induced by bis(2, 3-dichloro-1-propyl) ether.

    Neurath, G., Martin, F. L., Piasecki, A., Ruge, A., Cole, K. J., Franke, S., Francke, W. & Marquardt, H., 2000, In: ENVIRON MOL MUTAGEN. 35, 4, p. 312-318 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  54. Induction of 8-oxo-dGTPase activity in human lymphoid cells and normal fibroblasts by oxidative stress.

    Meyer, F., Fiala, E. & Westendorf, J., 2000, In: TOXICOLOGY. 146, 2-3, p. 83-92 2-3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  55. Induction of DNA strand-breaks in primary rat hepatocytes by ginkgolic acids.

    Westendorf, J. & Regan, J., 2000, In: PHARMAZIE. 55, 11, p. 864-865 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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