Institute of Experimental Pharmacology and Toxicology

Publications

  1. 2000
  2. Influence of treatment modality on angiographic outcome after coronary stenting in diabetic patients: a controlled study.

    Schofer, J., Schlüter, M., Rau, T., Hammer, F., Haag, N. & Mathey, D. G., 2000, In: J AM COLL CARDIOL. 35, 6, p. 1554-1559 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Nebivolol decreases systemic oxidative stress in healthy volunteers.

    Troost, R., Schwedhelm, E., Rojczyk, S., Tsikas, D. & Frölich, J. C., 2000, In: BRIT J CLIN PHARMACO. 50, 4, p. 377-379 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Normal oxidative stress and enhanced lipoprotein resistance to in vitro oxidation in hypertriglyceridemia: effects of bezafibrate therapy.

    de Man, F. H., Jonkers, I. J., Schwedhelm, E., Smelt, A. H., Onkenhout, W., VanDDuyvenvoorde, W., Buytenhek, R., Leuven, J. A., Troost, R., van Der Laarse, A. & Princen, H. M., 2000, In: ARTERIOSCL THROM VAS. 20, 11, p. 2434-2440 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Tandem mass spectrometric quantification of 8-iso-prostaglandin F2alpha and its metabolite 2,3-dinor-5,6-dihydro-8-iso-prostaglandin F2alpha in human urine.

    Schwedhelm, E., Tsikas, D., Durand, T., Gutzki, F. M., Guy, A., Rossi, J. C. & Frölich, J. C., 2000, In: J CHROMATOGR B. 744, 1, p. 99-112 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Transient expression of NMDA receptor subunit NR2B in the developing rat heart.

    Seeber, S., Becker, K., Rau, T., Eschenhagen, T., Becker, C. M. & Herkert, M., 2000, In: J NEUROCHEM. 75, 6, p. 2472-2477 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. UDS induction by an array of standard carcinogens in human and rodent hepatocytes: effect of cryopreservation.

    Schehrer, L., Regan, J. D. & Westendorf, J., 2000, In: TOXICOLOGY. 147, 3, p. 177-191 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. 1999
  9. Enhanced expression of CTLA-4 (CD152) on CD4+ T cells in HIV infection.

    Steiner, K., Waase, I., Rau, T., Dietrich, M., Fleischer, B. & Bröker, B. M., 1999, In: CLIN EXP IMMUNOL. 115, 3, p. 451-457 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Muscle LIM protein: expressed in slow muscle and induced in fast muscle by enhanced contractile activity.

    Schneider, A. G., Sultan, K. & Pette, D., 1999, In: AM J PHYSIOL-HEART C. 276(4 Pt 1), p. 900-906

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Pharmacological characterization of protein phosphatase activities in preparations from failing human hearts.

    Neumann, J., Maas, R., Bokník, P., Jones, L. R., Zimmermann, N. & Scholz, H., 1999, In: J PHARMACOL EXP THER. 289, 1, p. 188-193 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Restenosis after stenting of matched occluded and non-occluded coronary arteries. Should there be a difference?

    Schofer, J., Rau, T., Schlüter, M. & Mathey, D. G., 1999, In: EUR HEART J. 20, 16, p. 1175-1181 16.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Time-dependent changes in myosin heavy chain mRNA and protein isoforms in unloaded soleus muscle of rat.

    Stevens, L., Sultan, K., Peuker, H., Gohlsch, B., Mounier, Y. & Pette, D., 1999, In: AM J PHYSIOL-HEART C. 277(6 Pt 1), p. 1044-1049

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. 1998
  15. [Liver organ systems: valuation by gene expression]

    Sultan, K., Hartumg, J. & Bade Ernesto, G., 1998, In: ALTEX-ALTERN TIEREXP. 15, 1, p. 9-17 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Stenting of nonacute total coronary occlusions: predictors of late angiographic outcome.

    Rau, T., Schofer, J., Schlüter, M., Seidensticker, A., Berger, J. & Mathey, D. G., 1998, In: J AM COLL CARDIOL. 31, 2, p. 275-280 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. 1997
  18. Comparison of immediate and intermediate-term results of intravascular ultrasound versus angiography-guided Palmaz-Schatz stent implantation in matched lesions.

    Albiero, R., Rau, T., Schlüter, M., Di Mario, C., Reimers, B., Mathey, D. G., Tobis, J. M., Schofer, J. & Colombo, A., 1997, In: CIRCULATION. 96, 9, p. 2997-3005 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Genotoxicity assessment of suspended particulate matter in the Elbe river: comparison of Salmonella microsome test, arabinose resistance test, and umu-test.

    Vahl, H. H., Karbe, L. & Westendorf, J., 1997, In: MUTAT RES-FUND MOL M. 394, 1-3, p. 81-93 1-3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Short-term results and intermediate-term follow-up of laser wire recanalization of chronic coronary artery occlusions: a single-center experience.

    Schofer, J., Rau, T., Schlüter, M. & Mathey, D. G., 1997, In: J AM COLL CARDIOL. 30, 7, p. 1722-1728 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Uptake and metabolism of benzo(a)pyrene absorbed to sediment by the freshwater invertebrate species Chironomus riparius and Sphaerium corneum.

    Borchert, J., Karbe, L. & Westendorf, J., 1997, In: B ENVIRON CONTAM TOX. 58, 1, p. 158-165 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. 1996
  23. [Holiday heart syndrome]

    Rau, T. & Mathey, D., 1996, In: DEUT MED WOCHENSCHR. 121, 36, p. 1108 36.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Hormone- and endotoxin-modulated gene expression of a long-term organ culture system of adult rat liver.

    Sultan, K., Hartung, J. & Bade E, G., 1996, In: FEBS LETT. 394, 1, p. 51-54 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Mechanisms of the contractile effects of 2,3-butanedione-monoxime in the mammalian heart.

    Zimmermann, N., Boknik, P., Gams, E., Gsell, S., Jones, L. R., Maas, R., Neumann, J. & Scholz, H., 1996, In: N-S ARCH PHARMACOL. 354, 4, p. 431-436 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Pharmacological and toxicological aspects of new imidazoacridinone antitumor agents.

    Berger, B., Marquardt, H. & Westendorf, J., 1996, In: CANCER RES. 56, 9, p. 2094-2104 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Recanalization of chronic coronary artery occlusions using laser followed by balloon angioplasty.

    Schofer, J., Kresser, J., Rau, T., Kunze, K. P., Kühn, C. R. & Mathey, D. G., 1996, In: AM J CARDIOL. 78, 7, p. 836-838 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. 1993
  29. Aclacinomycin A in the treatment of experimental proliferative vitreoretinopathy. Efficacy and toxicity in the rabbit eye.

    Steinhorst, U. H., Chen, E. P., Hatchell, D. L., Samsa, G. P., Saloupis, P. T., Westendorf, J. & Machemer, R., 1993, In: INVEST OPHTH VIS SCI. 34, 5, p. 1753-1760 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Decreased resistance to N,N-dimethylated anthracyclines in multidrug-resistant Friend erythroleukemia cells.

    Schaefer, A., Westendorf, J., Lingelbach, K., Schmidt, C. A., Mihalache, D. L., Reymann, A. & Marquardt, H., 1993, In: CANCER CHEMOTH PHARM. 31, 4, p. 301-307 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. 1992
  32. Formation of genotoxic metabolites from anthraquinone glycosides, present in Rubia tinctorum L.

    Blömeke, B., Poginsky, B., Schmutte, C., Marquardt, H. & Westendorf, J., 1992, In: MUTAT RES-FUND MOL M. 265, 2, p. 263-272 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Mutagenicity testing of imidazole and related compounds.

    Forster, R., Blowers, S. D., Cinelli, S., Marquardt, H. & Westendorf, J., 1992, In: MUTAT RES-FUND MOL M. 298, 2, p. 71-79 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Two-dimensional nuclear magnetic resonance studies of an intercalation complex between the novel semisynthetic anthracycline 3'-deamino-3'-(2-methoxy-4-morpholinyl)-doxorubicin and the hexanucleotide duplex d(CGTACG).

    Odefey, C., Westendorf, J., Dieckmann, T. & Oschkinat, H., 1992, In: CHEM-BIOL INTERACT. 85, 2-3, p. 117-126 2-3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. 1991
  36. Evaluation of DNA-binding activity of hydroxyanthraquinones occurring in Rubia tinctorum L.

    Poginsky, B., Westendorf, J., Blömeke, B., Marquardt, H., Hewer, A., Grover, P. L. & Phillips, D. H., 1991, In: CARCINOGENESIS. 12, 7, p. 1265-1271 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. 1990
  38. Genotoxicity of naturally occurring hydroxyanthraquinones.

    Westendorf, J., Marquardt, H., Poginsky, B., Dominiak, M. & Schmidt, J., 1990, In: MUTAT RES-FUND MOL M. 240, 1, p. 1-12 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Hydroxyanthraquinones as tumor promoters: enhancement of malignant transformation of C3H mouse fibroblasts and growth stimulation of primary rat hepatocytes.

    Wölfle, D., Schmutte, C., Westendorf, J. & Marquardt, H., 1990, In: CANCER RES. 50, 20, p. 6540-6544 20.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Malignant transformation of mouse M2-fibroblasts by glycerol chlorohydrines contained in protein hydrolysates and commercial food.

    Piasecki, A., Ruge, A. & Marquardt, H., 1990, In: ARZNEIMITTEL-FORSCH. 40, 9, p. 1054-1055 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. 1989
  42. Mechanistic aspects of DNA damage by morpholinyl and cyanomorpholinyl anthracyclines.

    Westendorf, J., Aydin, M., Groth, G., Weller, O. & Marquardt, H., 1989, In: CANCER RES. 49, 19, p. 5262-5266 19.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Proliferation of fetal rat hepatocytes in response to growth factors and hormones in primary culture.

    Hoffmann, B., Piasecki, A. & Paul, D., 1989, In: J CELL PHYSIOL. 139, 3, p. 654-662 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. 1988
  45. Altered growth factor requirements and cell cycle control in rat hepatoma cells versus adult rat hepatocytes in culture.

    Paul, D., Piasecki, A., Baisch, H. & Begemann, M., 1988, In: EUR J CELL BIOL. 46, 2, p. 270-274 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Immortalized differentiated hepatocyte lines derived from transgenic mice harboring SV40 T-antigen genes.

    Paul, D., Höhne, M., Pinkert, C., Piasecki, A., Ummelmann, E. & Brinster, R. L., 1988, In: EXP CELL RES. 175, 2, p. 354-362 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Induction of erythroid differentiation by the anthracycline antitumor antibiotic pyrromycin.

    Steinheider, G., Schaefer, A., Westendorf, J. & Marquardt, H., 1988, In: CELL BIOL TOXICOL. 4, 1, p. 123-133 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Inhibition of amino acid uptake and incorporation into proteins in Friend erythroleukemia cells by the anthracycline antitumor antibiotic aclacinomycin A.

    Schaefer, A., Boldt, J., Westendorf, J., Steinheider, G. & Marquardt, H., 1988, In: BIOCHEM PHARMACOL. 37, 7, p. 1377-1382 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Mutagenic and antimutagenic effects of 5-substituted 2'-deoxyuridines depending on the nature of the 5-substituent.

    Marquardt, H., Westendorf, J., Schaefer, A., Boldt, J. & De Clercq, E., 1988, In: ARZNEIMITTEL-FORSCH. 38, 12, p. 1820-1824 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Possible carcinogenicity of anthraquinone-containing medical plants.

    Westendorf, J., Poginsky, B., Marquardt, H. & Kraus, L., 1988, In: PLANTA MED. 54, 6, p. 562 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. The genotoxicity of lucidin, a natural component of Rubia tinctorum L., and lucidinethylether, a component of ethanolic Rubia extracts.

    Westendorf, J., Poginsky, B., Marquardt, H. & Groth, G., 1988, In: CELL BIOL TOXICOL. 4, 2, p. 225-239 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. 1987
  53. Induction of chromosomal aberrations by the anthracycline antitumor antibiotics N,N-dimethyldaunomycin and aclacinomycin A.

    Steinheider, G., Westendorf, J. & Marquardt, H., 1987, In: Experientia. 43, 5, p. 586-588 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. Induction of malignant transformation in vitro and mammary tumors in rats by two new potent anthracycline antitumor antibiotics, morpholinodaunomycin and cyanomorpholinoadriamycin.

    Westendorf, J., Mohr, U. & Marquardt, H., 1987, In: CELL BIOL TOXICOL. 3, 1, p. 17-21 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. Transformation of differentiated neonatal rat hepatocytes in primary culture by polyoma virus early region sequences.

    Höhne, M., Piasecki, A., Ummelmann, E. & Paul, D., 1987, In: ONCOGENE. 1, 4, p. 337-345 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  56. 1986
  57. DNA interaction and mutagenicity of the plastic stabilizer di-n-octyltin dichloride.

    Westendorf, J. & Marquardt, H., 1986, In: ARZNEIMITTEL-FORSCH. 36, 8, p. 1263-1264 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  58. Induction of erythroid differentiation by the anthracycline antitumor antibiotics, aclacinomycin A, musettamycin and marcellomycin.

    Steinheider, G., Westendorf, J. & Marquardt, H., 1986, In: LEUKEMIA RES. 10, 10, p. 1233-1239 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  59. 1985
  60. Formation of DNA-adducts and induction of DNA-crosslinks and chromosomal aberrations by the new potent anthracycline antitumor antibiotics: morpholinodaunomycin, cyanomorpholinodaunomycin and cyanomorpholinoadriamycin.

    Westendorf, J., Groth, G., Steinheider, G. & Marquardt, H., 1985, In: CELL BIOL TOXICOL. 1, 2, p. 87-101 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  61. Potent anti-viral 5-(2-bromovinyl) uracil nucleosides are inactive at inducing gene mutations in Salmonella typhimurium and V79 Chinese hamster cells and unscheduled DNA synthesis in primary rat hepatocytes.

    Marquardt, H., Westendorf, J. & De Clercq, E., 1985, In: CARCINOGENESIS. 6, 8, p. 1207-1209 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  62. 1984
  63. [Biotransformation of monolinuron (N-(4-chlorophenyl)-N'-methyl-N'methoxyurea) in isolated perfused chicken liver].

    Westphal, D., Lucas, K., Hilbig, V., Mechler, U. & Piasecki, A., 1984, In: FOOD CHEM TOXICOL. 22, 7, p. 521-528 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  64. Rat platelets contain growth factor(s) distinct from PDGF which stimulate DNA synthesis in primary adult rat hepatocyte cultures.

    Paul, D. & Piasecki, A., 1984, In: EXP CELL RES. 154, 1, p. 95-100 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  65. Structure-activity relationship of anthracycline-induced genotoxicity in vitro.

    Westendorf, J. & Marquardt, H., 1984, In: CANCER RES. 44(12 Pt 1), p. 5599-5604

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review