Research ExplorerResearch UnitsInstitute of Experimental Pharmacology and Toxicology Publications

Institute of Experimental Pharmacology and Toxicology

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Publications

  1. 2024

  2. Sacubitril/valsartan reduces proteasome activation and cardiomyocyte area in an experimental mouse model of hypertrophy

    Meyer-Jens, M., Wenzel, K., Grube, K., Rüdebusch, J., Krämer, E., Bahls, M., Müller, K., Voß, H., Schlüter, H., Felix, S. B., Carrier, L., Könemann, S. & Schlossarek, S., 03.2024, In: Journal of molecular and cellular cardiology plus. 7, 100059.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. 2023

  4. Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES

    Schwarzová, B., Stüdemann, T., Sönmez, M., Rössinger, J., Pan, B., Eschenhagen, T., Stenzig, J., Wiegert, J. S., Christ, T. & Weinberger, F., 12.2023, In: PFLUG ARCH EUR J PHY. 475, 12, p. 1463-1477 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: a two-hit model of hypertrophic cardiomyopathy

    Nollet, E. E., Algül, S., Goebel, M., Schlossarek, S., van der Wel, N. N., Jans, J. J. M., van de Wiel, M. A., Knol, J. C., Pham, T. C., Piersma, S. R., de Goeij-de Haas, R., Hermans, J., van Klinken, J. B., van Weeghel, M., Houtkooper, R. H., Carrier, L., Jimenez, C. R., Kuster, D. W. D. & van der Velden, J., 19.11.2023, In: Journal of molecular and cellular cardiology plus. 6, 100050.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. A critical role of retinoic acid concentration for the induction of a fully human-like atrial action potential phenotype in hiPSC-CM

    Schulz, C., Sönmez, M., Krause, J., Schwedhelm, E., Bangfen, P., Alihodzic, D., Hansen, A., Eschenhagen, T. & Christ, T., 14.11.2023, In: STEM CELL REP. 18, 11, p. 2096-2107 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel mechanism

    Loos, M., Klampe, B., Schulze, T., Yin, X., Theofilatos, K., Ulmer, B. M., Schulz, C., Behrens, C. S., van Bergen, T. D., Adami, E., Maatz, H., Schweizer, M., Brodesser, S., Skryabin, B. V., Rozhdestvensky, T. S., Bodbin, S., Stathopoulou, K., Christ, T., Denning, C., Hübner, N., Mayr, M., Cuello, F., Eschenhagen, T. & Hansen, A., 14.11.2023, In: STEM CELL REP. 18, 11, p. 2123-2137 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. The W101C KCNJ5 Mutation Induces Slower Pacing by Constitutively Active GIRK Channels in hiPSC-Derived Cardiomyocytes

    Kayser, A., Dittmann, S., Šarić, T., Mearini, G., Verkerk, A. O. & Schulze-Bahr, E., 18.10.2023, In: INT J MOL SCI. 24, 20, p. 15290

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Organ-specific model of simulated ischemia/reperfusion and hyperglycemia based on engineered heart tissue

    Pálóczi, J., Paál, Á., Pigler, J., Kiss, B., Rhoden, A., Varga, Z. V., Ferdinandy, P., Eschenhagen, T. & Görbe, A., 10.2023, In: VASC PHARMACOL. 152, p. 107208 107208.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Generation of a homozygous CRYAB p.Arg120Gly mutant (UKEi001-A-1) from a human iPSC line

    Pietsch, N., Cheng, J., Fazio, A., Ewald, L., Alizoti, E., Krämer, E., Orthey, E., Carrier, L. & Singh, S. R., 09.2023, In: STEM CELL RES. 71, p. 103188

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. An arrhythmogenic metabolite in atrial fibrillation

    Krause, J., Nickel, A., Madsen, A., Aitken-Buck, H. M., Stoter, A. M. S., Schrapers, J., Ojeda, F., Geiger, K., Kern, M., Kohlhaas, M., Bertero, E., Hofmockel, P., Hübner, F., Assum, I., Heinig, M., Müller, C., Hansen, A., Krause, T., Park, D-D., Just, S., Aïssi, D., Börnigen, D., Lindner, D., Friedrich, N., Alhussini, K., Bening, C., Schnabel, R. B., Karakas, M., Iacoviello, L., Salomaa, V., Linneberg, A., Tunstall-Pedoe, H., Kuulasmaa, K., Kirchhof, P., Blankenberg, S., Christ, T., Eschenhagen, T., Lamberts, R. R., Maack, C., Stenzig, J. & Zeller, T., 24.08.2023, In: J TRANSL MED. 21, 1, p. 566

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy

    Algül, S., Schuldt, M., Manders, E., Jansen, V., Schlossarek, S., de Goeij-de Haas, R., Henneman, A. A., Piersma, S. R., Jimenez, C. R., Michels, M., Carrier, L., Helmes, M., van der Velden, J. & Kuster, D. W. D., 18.08.2023, In: CIRC RES. 133, 5, p. 387-399 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Mind the gap: leak currents and induced pluripotent stem cell-derived cardiomyocytes in translational cardiac electrophysiology

    Heijman, J. & Christ, T., 02.08.2023, In: EUROPACE. 25, 9, euad236.

    Research output: SCORING: Contribution to journal › Editorial › Research

  14. The DZHK research platform: Maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies

    Hoffmann, J., Hanß, S., Kraus, M., Schaller, J., Schäfer, C., Stahl, D., Anker, S. D., Anton, G., Bahls, T., Blankenberg, S., Blumentritt, A., Boldt, L-H., Cordes, S., Desch, S., Doehner, W., Dörr, M., Edelmann, F., Eitel, I., Endres, M., Engelhardt, S., Erdmann, J., Eulenburg, K., Falk, V., Felix, S. B., Frank, D., Franke, T., Frey, N., Friede, T., Geidel, L., Germans, L., Grabmaier, U., Halle, M., Hausleiter, J., Jakobi, V., Jebran, A-F., Jobs, A., Kääb, S., Karakas, M., Katus, H. A., Klatt, A., Knosalla, C., Krebser, J., Landmesser, U., Lee, M., Lehnert, K., Lesser, S., Leyh, K., Lorbeer, R., Mach-Kolb, S., Meder, B., Nagel, E., Nolte, C. H., Parwani, A. S., Petersmann, A., Puls, M., Rau, H., Reiser, M., Rienhoff, O., Scharfe, T., Schattschneider, M., Scheel, H., Schnabel, R. B., Schuster, A., Schmitt, B., Seidler, T., Seiffert, M., Stähli, B-E., Stas, A., J Stocker, T., von Stülpnagel, L., Thiele, H., Wachter, R., Wakili, R., Weis, T., Weitmann, K., Wichmann, H-E., Wild, P., Zeller, T., Hoffmann, W., Zeisberg, E. M., Zimmermann, W-H., Krefting, D., Kühne, T., Peters, A., Hasenfuß, G., Massberg, S., Sommer, T., Dimmeler, S., Eschenhagen, T. & Nauck, M., 07.2023, In: CLIN RES CARDIOL. 112, 7, p. 923-941 19 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy

    Braun, F., Abed, A., Sellung, D., Rogg, M., Woidy, M., Eikrem, O., Wanner, N., Gambardella, J., Laufer, S. D., Haas, F., Wong, M. N., Dumoulin, B., Rischke, P., Mühlig, A. K., Sachs, W., von Cossel, K., Schulz, K., Muschol, N., Gersting, S. W., Muntau, A. C., Kretz, O., Hahn, O., Rinschen, M. M., Mauer, M., Bork, T., Grahammer, F., Liang, W., Eierhoff, T., Römer, W., Hansen, A., Meyer-Schwesinger, C., Iaccarino, G., Tøndel, C., Marti, H-P., Najafian, B., Puelles, V. G., Schell, C. & Huber, T. B., 01.06.2023, In: J CLIN INVEST. 133, 11, e157782.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Immature human engineered heart tissues engraft in a guinea pig chronic injury model

    von Bibra, C., Shibamiya, A., Bähr, A., Geertz, B., Köhne, M., Stuedemann, T., Starbatty, J., Horneffer-van der Sluis, V., Klostermeier, U. C., Hornaschewitz, N., Li, X., Wolf, E., Klymiuk, N., Krane, M., Kupatt, C., Hiebl, B., Eschenhagen, T. & Weinberger, F., 01.05.2023, In: DIS MODEL MECH. 16, 5, dmm049834.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Kardiale Biomarker und ihre klinische Bedeutung

    Eschenhagen, T. & Kirchhof, P., 05.2023, In: DEUT MED WOCHENSCHR. 148, 10, p. 605-609 5 p.

    Research output: SCORING: Contribution to journal › Training articles › Research › peer-review

  18. Valvular Cardiomyopathy in Aortic Valve Regurgitation Correlates with Myocardial Fibrosis

    Petersen, J., Iqbal, S., Gedeon, N., Kloth, B., Pecha, S., Yildirim, Y., Eschenhagen, T., Reichenspurner, H., Christ, T. & Girdauskas, E., 17.04.2023, In: J CLIN MED. 12, 8, 2915.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. The detyrosination/re-tyrosination cycle of tubulin and its role and dysfunction in neurons and cardiomyocytes

    Sanyal, C., Pietsch, N., Ramirez Rios, S., Peris, L., Carrier, L. & Moutin, M-J., 15.03.2023, In: SEMIN CELL DEV BIOL. 137, p. 46-62 17 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  20. Proteomic Analysis in Valvular Cardiomyopathy: Aortic Regurgitation vs. Aortic Stenosis

    Holst, T., Petersen, J., Ameling, S., Müller, L., Christ, T., Gedeon, N., Eschenhagen, T., Reichenspurner, H., Hammer, E. & Girdauskas, E., 11.03.2023, In: CELLS-BASEL. 12, 6, 878.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. PITX2 Knockout Induces Key Findings of Electrical Remodeling as Seen in Persistent Atrial Fibrillation

    Schulz, C., Lemoine, M. D., Mearini, G., Koivumäki, J., Sani, J., Schwedhelm, E., Kirchhof, P., Ghalawinji, A., Stoll, M., Hansen, A., Eschenhagen, T. & Christ, T., 03.2023, In: CIRC-ARRHYTHMIA ELEC. 16, 3, p. e011602

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Resting membrane potential is less negative in trabeculae from right atrial appendages of women, but action potential duration does not shorten with age

    Pecha, S., Ismaili, D., Geelhoed, B., Knaut, M., Reichenspurner, H., Eschenhagen, T., Schnabel, R. B., Christ, T. & Ravens, U., 03.2023, In: J MOL CELL CARDIOL. 176, p. 1-10 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Repolarization indicates electrical instability in ventricular arrhythmia originating from papillary muscle

    Münkler, P., Klatt, N., Scherschel, K., Kuklik, P., Jungen, C., Cavus, E., Eickholt, C., Christoph, J., Lemoine, M. D., Christ, T., Willems, S., Riedel, R., Kirchhof, P. & Meyer, C., 16.02.2023, In: EUROPACE. 25, 2, p. 688–697 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Arterielle Hypertonie

    Eschenhagen, T. & Weil, J., 2023, Arzneiverordnungs-Report 2022. Ludwig, P. W-D., Mühlbauer, P. B. & Seifert, P. R. (eds.). 1 ed. Berlin, Heidelberg: Springer, p. 155 - 203 49 p. 6

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Education › peer-review

  25. Harnessing the power of RNA therapeutics in treating ischemic heart failure: the TRAIN-HEART story

    Albert, A. M., Balamurali, D., Beslika, E., Fernandez, I. D., Genedy, H. H., Babaei Khorzoughi, R., Lauta, F. C., Peppas, P., Ragone, I., Rizzari, G., Sansonetti, M., Silva, J., Spanò, G. & Wrona, K. M., 2023, In: FRONT CARDIOVASC MED. 10, p. 1228160

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  26. Herzerkrankungen

    Eschenhagen, T. & Weil, J., 2023, Arzneiverordnungs-Report 2022 . Ludwig, P. W-D., Mühlbauer, P. B. & Seifert, P. R. (eds.). 1 ed. Berlin, Heidelberg: Springer, p. 205 - 220 16 p. 7

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Education › peer-review

  27. Human induced pluripotent stem cell-derived cardiomyocytes as an electrophysiological model: Opportunities and challenges-The Hamburg perspective

    Ismaili, D., Schulz, C., Horváth, A., Koivumäki, J. T., Mika, D., Hansen, A., Eschenhagen, T. & Christ, T., 2023, In: FRONT PHYSIOL. 14, p. 1132165

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  28. Hypoxia to Stimulate Cardiomyocyte Proliferation After MI? A Word of Caution

    Eschenhagen, T., 2023, In: CIRC RES. 132, 6, p. 741-743 3 p.

    Research output: SCORING: Contribution to journal › Editorial › Research

  29. Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes

    Fischer, M., Jakab, M., Hirt, M. N., Werner, T. R., Engelhardt, S. & Sarikas, A., 2023, In: FRONT PHYSIOL. 14, p. 1134339

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Jeanette Erdmann (1965–2023)

    Aherrahrou, R., Eschenhagen, T., König, I. R., Samani, N. J., Schunkert, H. & Aherrahrou, Z., 2023, In: NAT GENET. 55, 12, p. 2016-2017 2 p.

    Research output: SCORING: Contribution to journal › Editorial › Research

  31. 2022

  32. G Protein-Coupled Receptor 15 Expression Is Associated with Myocardial Infarction

    Haase, T., Müller, C., Stoffers, B., Kirn, P., Waldenberger, M., Kaiser, F. J., Karakas, M., Kim, S. V., Voss, S., Wild, P. S., Lackner, K. J., Andersson, J., Söderberg, S., Lindner, D. & Zeller, T., 22.12.2022, In: INT J MOL SCI. 24, 1, 180.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart

    van der Velden, J., Asselbergs, F. W., Bakkers, J., Batkai, S., Bertrand, L., Bezzina, C. R., Bot, I., Brundel, B. J. J. M., Carrier, L., Chamuleau, S., Ciccarelli, M., Dawson, D., Davidson, S. M., Dendorfer, A., Duncker, D. J., Eschenhagen, T., Fabritz, L., Falcão-Pires, I., Ferdinandy, P., Giacca, M., Girao, H., Gollmann-Tepeköylü, C., Gyongyosi, M., Guzik, T. J., Hamdani, N., Heymans, S., Hilfiker, A., Hilfiker-Kleiner, D., Hoekstra, A. G., Hulot, J-S., Kuster, D. W. D., van Laake, L. W., Lecour, S., Leiner, T., Linke, W. A., Lumens, J., Lutgens, E., Madonna, R., Maegdefessel, L., Mayr, M., van der Meer, P., Passier, R., Perbellini, F., Perrino, C., Pesce, M., Priori, S., Remme, C. A., Rosenhahn, B., Schotten, U., Schulz, R., Sipido, K. R., Sluijter, J. P. G., van Steenbeek, F., Steffens, S., Terracciano, C. M., Tocchetti, C. G., Vlasman, P., Yeung, K. K., Zacchigna, S., Zwaagman, D., Thum, T. & ESC Working Group onMyocardial Function / ESC Working Group on Cellular Biology of the Heart, 09.12.2022, In: CARDIOVASC RES. 118, 15, p. 3016-3051 36 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  34. Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues

    Reed, E., Fellows, A., Lu, R., Rienks, M., Schmidt, L., Yin, X., Duregotti, E., Brandt, M., Krasemann, S., Hartmann, K., Barallobre-Barreiro, J., Addison, O., Cuello, F., Hansen, A. & Mayr, M., 12.2022, In: Matrix biology plus. 16, 100122.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Analyzing the brainstem circuits for respiratory chemosensitivity in freely moving mice

    Bhandare, A., van de Wiel, J., Roberts, R., Braren, I., Huckstepp, R. & Dale, N., 27.10.2022, In: ELIFE. 11, e70671.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. Effect of sulfasalazine on endothelium-dependent vascular response by the activation of Nrf2 signalling pathway

    Sonmez, M. I., Shahzadi, A., Kose, C., Sonmez, H., Ozyazgan, S. & Akkan, A. G., 24.10.2022, In: FRONT PHARMACOL. 13, 979300.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Contractile Force of Transplanted Cardiomyocytes Actively Supports Heart Function After Injury

    Stüdemann, T., Rössinger, J., Manthey, C., Geertz, B., Srikantharajah, R., von Bibra, C., Shibamiya, A., Köhne, M., Wiehler, A., Wiegert, J. S., Eschenhagen, T. & Weinberger, F., 11.10.2022, In: CIRCULATION. 146, 15, p. 1159-1169 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Activation of an accessory pathway of glucose metabolism to treat dilated cardiomyopathy

    Eschenhagen, T., 21.09.2022, In: EUR HEART J. 43, 36, p. 3490-3492 3 p.

    Research output: SCORING: Contribution to journal › Editorial › Research

  39. ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes

    Zech, A. T. L., Prondzynski, M., Singh, S. R., Pietsch, N., Orthey, E., Alizoti, E., Busch, J., Madsen, A., Behrens, C. S., Meyer-Jens, M., Mearini, G., Lemoine, M. D., Krämer, E., Mosqueira, D., Virdi, S., Indenbirken, D., Depke, M., Salazar, M. G., Völker, U., Braren, I., Pu, W. T., Eschenhagen, T., Hammer, E., Schlossarek, S. & Carrier, L., 02.09.2022, In: CELLS-BASEL. 11, 17, 2745.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Disease modeling of a mutation in α-actinin 2 guides clinical therapy in hypertrophic cardiomyopathy - Addendum

    Prondzynski, M., Lemoine, M. D., Zech, A. T., Horváth, A., Di Mauro, V., Koivumäki, J. T., Kresin, N., Busch, J., Krause, T., Krämer, E., Schlossarek, S., Spohn, M., Friedrich, F. W., Münch, J., Laufer, S. D., Redwood, C., Volk, A. E., Hansen, A., Mearini, G., Catalucci, D., Meyer, C., Christ, T., Patten, M., Eschenhagen, T. & Carrier, L., 08.08.2022, In: EMBO MOL MED. 14, 8, e16423.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  41. Regulation of APD and Force by the Na+/Ca2+ Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue

    Ismaili, D., Gurr, K., Horváth, A., Yuan, L., Lemoine, M. D., Schulz, C., Sani, J., Petersen, J., Reichenspurner, H., Kirchhof, P., Jespersen, T., Eschenhagen, T., Hansen, A., Koivumäki, J. T. & Christ, T., 05.08.2022, In: CELLS-BASEL. 11, 15, 2424.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. A biallelic loss-of-function variant in MYZAP is associated with a recessive form of severe dilated cardiomyopathy

    Maver, A., Zigman, T., Rangrez, A. Y., Coric, M., Homolak, J., Saric, D., Skific, I., Udovicic, M., Zekusic, M., Saleem, U., Laufer, S. D., Hansen, A., Frey, N., Baric, I. & Peterlin, B., 15.07.2022, In: CSH MOL CASE STUD. 8, 5, a006221.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. A potential future Fontan modification: preliminary in vitro data of a pressure-generating tube from engineered heart tissue

    Köhne, M., Behrens, C. S., Stüdemann, T., Bibra, C. V., Querdel, E., Shibamiya, A., Geertz, B., Olfe, J., Hüners, I., Jockenhövel, S., Hübler, M., Eschenhagen, T., Sachweh, J. S., Weinberger, F. & Biermann, D., 11.07.2022, In: EUR J CARDIO-THORAC. 62, 2, ezac111.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Erratum. Performance of the ESC 0/1-h and 0/3-h Algorithm for the Rapid Identification of Myocardial Infarction Without ST-Elevation in Patients With Diabetes. Diabetes Care 2020;43:460-467

    Haller, P. M., Boeddinghaus, J., Neumann, J. T., Sörensen, N. A., Hartikainen, T. S., Goßling, A., Nestelberger, T., Twerenbold, R., Lehmacher, J., Keller, T., Zeller, T., Blankenberg, S., Mueller, C. & Westermann, D., 07.07.2022, In: DIABETES CARE. 45, 7, p. 1701-1702 2 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  45. Human-Engineered Atrial Tissue for Studying Atrial Fibrillation

    Krause, J., Lemme, M., Mannhardt, I., Eder, A., Ulmer, B., Eschenhagen, T. & Stenzig, J., 27.05.2022, Cardiac Tissue Engineering: Methods and Protocols. Coulombe, K. L. K. & Black III, L. D. (eds.). 1 ed. New York, NY: Humana Press, p. 159-173 15 p. (Methods in Molecular Biology; vol. 2485).

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research

  46. Interpretation and actionability of genetic variants in cardiomyopathies: a position statement from the European Society of Cardiology Council on cardiovascular genomics

    Arbustini, E., Behr, E. R., Carrier, L., van Duijn, C., Evans, P., Favalli, V., van der Harst, P., Haugaa, K. H., Jondeau, G., Kääb, S., Kaski, J. P., Kavousi, M., Loeys, B., Pantazis, A., Pinto, Y., Schunkert, H., Di Toro, A., Thum, T., Urtis, M., Waltenberger, J. & Elliott, P., 21.05.2022, In: EUR HEART J. 43, 20, p. 1901-1916 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  47. Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes

    Kloth, B., Mearini, G., Weinberger, F., Stenzig, J., Geertz, B., Starbatty, J., Lindner, D., Schumacher, U., Reichenspurner, H., Eschenhagen, T. & Hirt, M. N., 17.05.2022, In: SCI REP-UK. 12, 1, 8193.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Muscarinic Receptor Activation Reduces Force and Arrhythmias in Human Atria Independent of IK,ACh

    Petersen, J., Castro, L., Bengaard, A. K., Pecha, S., Ismaili, D., Schulz, C., Sahni, J., Steenpass, A., Meier, C., Reichenspurner, H., Jespersen, T., Eschenhagen, T. & Christ, T., 01.05.2022, In: J CARDIOVASC PHARM. 79, 5, p. 678-686 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes

    Wickramasinghe, N. M., Sachs, D., Shewale, B., Gonzalez, D. M., Dhanan-Krishnan, P., Torre, D., LaMarca, E., Raimo, S., Dariolli, R., Serasinghe, M. N., Mayourian, J., Sebra, R., Beaumont, K., Iyengar, S., French, D. L., Hansen, A., Eschenhagen, T., Chipuk, J. E., Sobie, E. A., Jacobs, A., Akbarian, S., Ischiropoulos, H., Ma'ayan, A., Houten, S. M., Costa, K. & Dubois, N. C., 07.04.2022, In: CELL STEM CELL. 29, 4, p. 559-576.e7

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. The guinea pig model in cardiac regeneration research. Current tissue engineering approaches and future directions

    Stüdemann, T. & Weinberger, F., 10.03.2022, Advanced Technologies in Cardiovascular Bioengineering. Zhang, J. & Serpooshan, V. (eds.). 1 ed. Springer International Publishing, p. 103-122 20 p.

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research

  51. Comprehensive analyses of the inotropic compound omecamtiv mecarbil in rat and human cardiac preparations

    Rhoden, A., Schulze, T., Pietsch, N., Christ, T., Hansen, A. & Eschenhagen, T., 01.03.2022, In: AM J PHYSIOL-HEART C. 322, 3, p. H373-H385

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. RGS3L allows for an M2 muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes

    Levay, M. K., Krobert, K. A., Vogt, A., Ahmad, A., Jungmann, A., Neuber, C., Pasch, S., Hansen, A., Müller, O. J., Lutz, S. & Wieland, T., 01.03.2022, In: BASIC RES CARDIOL. 117, 1, 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC)

    de Boer, R. A., Heymans, S., Backs, J., Carrier, L., Coats, A. J. S., Dimmeler, S., Eschenhagen, T., Filippatos, G., Gepstein, L., Hulot, J-S., Knöll, R., Kupatt, C., Linke, W. A., Seidman, C. E., Tocchetti, C. G., van der Velden, J., Walsh, R., Seferovic, P. M. & Thum, T., 03.2022, In: EUR J HEART FAIL. 24, 3, p. 406-420 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

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