Institute of Experimental Pharmacology and Toxicology
Publications
- 2022
How to repair a broken heart with pluripotent stem cell-derived cardiomyocytes
Eschenhagen, T., Ridders, K. & Weinberger, F., 02.2022, In: J MOL CELL CARDIOL. 163, p. 106-117 12 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Recapitulation of dyssynchrony-associated contractile impairment in asymmetrically paced engineered heart tissue
Stenzig, J., Lemoine, M. D., Stoter, A. M. S., Wrona, K. M., Lemme, M., Mulla, W., Etzion, Y., Eschenhagen, T. & Hirt, M. N., 02.2022, In: J MOL CELL CARDIOL. 163, p. 97-105 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human engineered heart tissue transplantation in a guinea pig chronic injury model
von Bibra, C., Shibamiya, A., Geertz, B., Querdel, E., Köhne, M., Stüdemann, T., Starbatty, J., Schmidt, F. N., Hansen, A., Hiebl, B., Eschenhagen, T. & Weinberger, F., 23.01.2022, In: J MOL CELL CARDIOL. 166, p. 1-10 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An Improved Model of Moderate Sleep Apnoea for Investigating Its Effect as a Comorbidity on Neurodegenerative Disease
Roberts, R., Wall, M. J., Braren, I., Dhillon, K., Evans, A., Dunne, J., Nyakupinda, S. & Huckstepp, R. T. R., 2022, In: FRONT AGING NEUROSCI. 14, 861344.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CMYA5 is a novel interaction partner of FHL2 in cardiac myocytes
Stathopoulou, K., Schnittger, J., Raabe, J., Fleischer, F., Mangels, N., Piasecki, A., Findlay, J., Hartmann, K., Krasemann, S., Schlossarek, S., Uebeler, J., Wixler, V., Blake, D. J., Baillie, G. S., Carrier, L., Ehler, E. & Cuello, F., 2022, In: FEBS J. 289, 15, p. 4622-4645Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Enhanced Transduction of P2X7-Expressing Cells with Recombinant rAAV Vectors
Mann, A. M., Schäfer, W., Adriouch, S., Börner, K., Grimm, D., Braren, I. & Koch-Nolte, F., 2022, The P2X7 Receptor: Methods and Protocols. Nicke, A. (ed.). 1 ed. New York, NY: HUMANA PRESS INC, p. 129-144 16 p. (Methods in Molecular Biology; vol. 2510).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I
Kamynina, A., Guttzeit, S., Eaton, P. & Cuello, F., 2022, In: HYPERTENSION. 79, 5, p. 946-956Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling
Barallobre-Barreiro, J., Radovits, T., Fava, M., Mayr, U., Lin, W-Y., Ermolaeva, E., Martínez-López, D., Lindberg, E. L., Duregotti, E., Daróczi, L., Hasman, M., Schmidt, L. E., Singh, B., Lu, R., Baig, F., Siedlar, A. M., Cuello, F., Catibog, N., Theofilatos, K., Shah, A. M., Crespo-Leiro, M. G., Doménech, N., Hübner, N., Merkely, B. & Mayr, M., 21.12.2021, In: CIRCULATION. 144, 25, p. 2021-2034 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of the PLN p.Arg14del Mutation in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Badone, B., Ronchi, C., Lodola, F., Knaust, A. E., Hansen, A., Eschenhagen, T. & Zaza, A., 16.12.2021, In: INT J MOL SCI. 22, 24Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue
Radke, M. H., Badillo-Lisakowski, V., Britto-Borges, T., Kubli, D. A., Jüttner, R., Parakkat, P., Carballo, J. L., Hüttemeister, J., Liss, M., Hansen, A., Dieterich, C., Mullick, A. E. & Gotthardt, M., 01.12.2021, In: SCI TRANSL MED. 13, 622, eabe8952.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Contractile force of transplanted cardiomyocytes contributes to heart function after injury
Stüdemann, T., Rössinger, J., Manthey, C., Geertz, B., Srikantharajah, R., Bibra, C. V., Shibamiya, A., Köhne, M., Wiehler, A., Wiegert, J. S., Eschenhagen, T. & Weinberger, F., 23.11.2021, bioRxivResearch output: Other contribution › Other › Research
A Novel miRNA Screen Identifies miRNA-4454 as a Candidate Biomarker for Ventricular Fibrosis in Patients with Hypertrophic Cardiomyopathy
Thottakara, T., Lund, N., Krämer, E., Kirchhof, P., Carrier, L. & Patten, M., 18.11.2021, In: BIOMOLECULES. 11, 11, 1718.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Incomplete Assembly of the Dystrophin-Associated Protein Complex in 2D and 3D-Cultured Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Gilbert, G., Kadur Nagaraju, C., Duelen, R., Amoni, M., Bobin, P., Eschenhagen, T., Roderick, H. L., Sampaolesi, M. & Sipido, K. R., 04.11.2021, In: FRONT CELL DEV BIOL. 9, 737840.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bluthochdruck - Herz und Gefäße schützen: Medikamente - Die richtige Wahl treffen
Hirt, M., Stenzig, J. & Eschenhagen, T., 11.2021, Frankfurt ma Main: Deutsche Herzstiftung e.V. 8 p.Research output: Book/anthology › Compendium/lecture notes
Angiotensin II receptor blocker intake associates with reduced markers of inflammatory activation and decreased mortality in patients with cardiovascular comorbidities and COVID-19 disease
Cremer, S., Pilgram, L., Berkowitsch, A., Stecher, M., Rieg, S., Shumliakivska, M., Bojkova, D., Wagner, J. U. G., Aslan, G. S., Spinner, C., Luxán, G., Hanses, F., Dolff, S., Piepel, C., Ruppert, C., Guenther, A., Rüthrich, M. M., Vehreschild, J. J., Wille, K., Haselberger, M., Heuzeroth, H., Hansen, A., Eschenhagen, T., Cinatl, J., Ciesek, S., Dimmeler, S., Borgmann, S., Zeiher, A. & LEOSS study group, 21.10.2021, In: PLOS ONE. 16, 10, e0258684.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
New Strategies for the Treatment of Atrial Fibrillation
Jost, N., Christ, T. & Magyar, J., 15.09.2021, In: PHARMACEUTICALS-BASE. 14, 9, 926.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
In vivo grafting of large engineered heart tissue patches for cardiac repair
Jabbour, R. J., Owen, T. J., Pandey, P., Reinsch, M., Wang, B., King, O., Couch, L. S., Pantou, D., Pitcher, D. S., Chowdhury, R. A., Pitoulis, F. G., Handa, B. S., Kit-Anan, W., Perbellini, F., Myles, R. C., Stuckey, D. J., Dunne, M., Shanmuganathan, M., Peters, N. S., Ng, F. S., Weinberger, F., Terracciano, C. M., Smith, G. L., Eschenhagen, T. & Harding, S. E., 09.08.2021, In: JCI INSIGHT. 6, 15, e144068.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ouabain worsens diastolic sarcomere length in myocytes from a cardiomyopathy mouse model
Düsener, S., Flenner, F., Maack, C., Kohlhaas, M., Bay, J., Carrier, L. & Friedrich, F. W., 05.08.2021, In: EUR J PHARMACOL. 904, 174170.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy
Warnecke, N. A., Ulmer, B. M., Laufer, S. D., Shibamiya, A., Krämer, E., Neuber, C., Hanke, S., Behrens, C., Loos, M., Münch, J., Kühnisch, J., Klaassen, S., Eschenhagen, T., Patten-Hamel, M., Carrier, L. & Mearini, G., 08.2021, In: STEM CELL RES. 55, p. 102489Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Translational investigation of electrophysiology in hypertrophic cardiomyopathy
Flenner, F., Jungen, C., Küpker, N., Ibel, A., Kruse, M., Koivumäki, J. T., Rinas, A., Zech, A. T. L., Rhoden, A., Wijnker, P. J. M., Lemoine, M. D., Steenpass, A., Girdauskas, E., Eschenhagen, T., Meyer, C., van der Velden, J., Patten-Hamel, M., Christ, T. & Carrier, L., 08.2021, In: J MOL CELL CARDIOL. 157, p. 77-89 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blunted beta-adrenoceptor-mediated inotropy in valvular cardiomyopathy: another piece of the puzzle in human aortic valve disease
Petersen, J., Kloth, B., Iqbal, S., Reichenspurner, H., Geelhoed, B., Schnabel, R., Eschenhagen, T., Christ, T. & Girdauskas, E., 14.07.2021, In: EUR J CARDIO-THORAC. 60, 1, p. 56-63 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation
Cuello, F., Knaust, A. E., Saleem, U., Loos, M., Raabe, J., Mosqueira, D., Laufer, S., Schweizer, M., van der Kraak, P., Flenner, F., Ulmer, B. M., Braren, I., Yin, X., Theofilatos, K., Ruiz-Orera, J., Patone, G., Klampe, B., Schulze, T., Piasecki, A., Pinto, Y., Vink, A., Hübner, N., Harding, S., Mayr, M., Denning, C., Eschenhagen, T. & Hansen, A., 07.06.2021, In: EMBO MOL MED. 13, 6, p. e13074Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regulation of basal and norepinephrine-induced cAMP and ICa in hiPSC-cardiomyocytes: Effects of culture conditions and comparison to adult human atrial cardiomyocytes
Iqbal, Z., Ismaili, D., Dolce, B., Petersen, J., Reichenspurner, H., Hansen, A., Kirchhof, P., Eschenhagen, T., Nikolaev, V. O., Molina, C. E. & Christ, T., 06.2021, In: CELL SIGNAL. 82, p. 109970Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cardiovascular magnetic resonance detects microvascular dysfunction in a mouse model of hypertrophic cardiomyopathy
Ku, M-C., Kober, F., Lai, Y-C., Pohlmann, A., Qadri, F., Bader, M., Carrier, L. & Niendorf, T., 31.05.2021, In: J CARDIOVASC MAGN R. 23, 1, p. 63Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human Engineered Heart Tissue Patches Remuscularize the Injured Heart in a Dose-Dependent Manner
Querdel, E., Reinsch, M., Castro, L., Köse, D., Bähr, A., Reich, S., Geertz, B., Ulmer, B., Schulze, M., Lemoine, M. D., Krause, T., Lemme, M., Sani, J., Shibamiya, A., Stüdemann, T., Köhne, M., Bibra, C. V., Hornaschewitz, N., Pecha, S., Nejahsie, Y., Mannhardt, I., Christ, T., Reichenspurner, H., Hansen, A., Klymiuk, N., Krane, M., Kupatt, C., Eschenhagen, T. & Weinberger, F., 18.05.2021, In: CIRCULATION. 143, 20, p. 1991-2006 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hypertrophic signaling compensates for contractile and metabolic consequences of DNA methyltransferase 3A loss in human cardiomyocytes
Madsen, A., Krause, J., Höppner, G., Hirt, M. N., Tan, W. L. W., Lim, I., Hansen, A., Nikolaev, V. O., Foo, R. S. Y., Eschenhagen, T. & Stenzig, J., 05.2021, In: J MOL CELL CARDIOL. 154, p. 115-123 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sulforaphane exposure impairs contractility and mitochondrial function in three-dimensional engineered heart tissue
Rhoden, A., Friedrich, F. W., Brandt, T., Raabe, J., Schweizer, M., Meisterknecht, J., Wittig, I., Ulmer, B. M., Klampe, B., Uebeler, J., Piasecki, A., Lorenz, K., Eschenhagen, T., Hansen, A. & Cuello, F., 05.2021, In: REDOX BIOL. 41, p. 101951Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regulation of Cardiac PKA Signaling by cAMP and Oxidants
Cuello, F., Herberg, F. W., Stathopoulou, K., Henning, P. & Diering, S., 24.04.2021, In: ANTIOXIDANTS-BASEL. 10, 5, p. 663Research output: SCORING: Contribution to journal › SCORING: Review article › Research
FYCO1 regulates cardiomyocyte autophagy and prevents heart failure due to pressure overload in vivo
Kuhn, C., Menke, M., Senger, F., Mack, C., Dierck, F., Hille, S., Schmidt, I., Brunke, G., Bünger, P., Schmiedel, N., Will, R., Sossalla, S., Frank, D., Eschenhagen, T., Carrier, L., Lüllmann-Rauch, R., Yusuf, A. & Frey, N., 04.2021, In: JACC-BASIC TRANSL SC. 6, 4, p. 365-380 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Are atrial human pluripotent stem cell-derived cardiomyocytes ready to identify drugs that beat atrial fibrillation?
Christ, T., Lemoine, M. D. & Eschenhagen, T., 19.03.2021, In: NAT COMMUN. 12, 1, p. 1725Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Cas9-expressing chickens and pigs as resources for genome editing in livestock
Rieblinger, B., Sid, H., Bozoglu, T., Klinger, R., Schlickenrieder, A., Lengyel, K., Flisikowski, K., Flisikowska, T., Simm, N., Grodziecki, A., Perleberg, C., Bähr, A., Carrier, L., Wolf, E., Kessler, B., Kettler, L., Luksch, H., Hagag, I. T., Wise, D., Kaufman, J., Kaufer, B. B., Kupatt, C., Schnieke, A. & Schusser, B., 09.03.2021, In: P NATL ACAD SCI USA. 118, 10, e2022562118.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DNA Methylation in Heart Failure
Anene-Nzelu, C. G., Stenzig, J. & Foo, R., 06.03.2021, Epigenetics in Cardiovascular Disease. Devaux, Y. & Robinson, E. (eds.). 1 ed. Elsevier Inc., Vol. 24. p. 55-76 12 p. (Translational Epigenetics).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research
Cardiac Hypertrophy Changes Compartmentation of cAMP in Non-Raft Membrane Microdomains
Pavlaki, N., De Jong, K. A., Geertz, B., Nikolaev, V. O. & Froese, A., 03.03.2021, In: CELLS-BASEL. 10, 3, 535.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: The New Working Horse in Cardiovascular Pharmacology?
Lemoine, M. D. & Christ, T., 01.03.2021, In: J CARDIOVASC PHARM. 77, 3, p. 265-266 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
No impact of sex and age on beta-adrenoceptor-mediated inotropy in human right atrial trabeculae
Pecha, S., Geelhoed, B., Kempe, R., Berk, E., Engel, A., Girdauskas, E., Reichenspurner, H., Ravens, U., Kaumann, A., Eschenhagen, T., Schnabel, R. B. & Christ, T., 03.2021, In: ACTA PHYSIOL. 231, 3, e13564.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cardiac Regeneration: New Hope for an Old Dream
Weinberger, F. & Eschenhagen, T., 10.02.2021, In: ANNU REV PHYSIOL. 83, p. 59-81 23 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation
Dolce, B., Christ, T., Grammatika Pavlidou, N., Yildirim, Y., Reichenspurner, H., Eschenhagen, T., Nikolaev, V. O., Kaumann, A. J. & Molina, C. E., 02.2021, In: N-S ARCH PHARMACOL. 394, 2, p. 291-298 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Proteomic and functional studies reveal detyrosinated tubulin as treatment target in sarcomere mutation-induced hypertrophic cardiomyopathy
Schuldt, M., Pei, J., Harakalova, M., Dorsch, L. M., Schlossarek, S., Mokry, M., Knol, J. C., Pham, T. V., Schelfhorst, T., Piersma, S. S., Dos Remedios, C., Dalinghaus, M., Michels, M., Asselbergs, F. W., Moutin, M-J., Carrier, L., Jimenez, C. R., van der Velden, J. & Kuster, D. W. D., 12.01.2021, In: CIRC-HEART FAIL. 14, 1, p. e007022 e007022.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Toward standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function
Zacchigna, S., Paldino, A., Falcão-Pires, I., Daskalopoulos, E. P., Dal Ferro, M., Vodret, S., Lesizza, P., Cannatà, A., Miranda-Silva, D., Lourenço, A. P., Pinamonti, B., Sinagra, G., Weinberger, F., Eschenhagen, T., Carrier, L., Kehat, I., Russo, M., Tocchetti, C. G., Ghigo, A., Hirsch, E., Dawson, D., Ciccarelli, M., Oliveti, M., Linke, W. A., Cuijpers, I., Heymans, S., Hamdani, N., de Boer, M., Duncker, D. J., Kuster, D. W. D., van der Velden, J., Beauloye, C., Bertrand, L., Mayr, M., Giacca, M., Leuschner, F., Backs, J. & Thum, T., 01.01.2021, In: CARDIOVASC RES. 117, 1, p. 43-59Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Autophagy, 01.2021, In: AUTOPHAGY. 17, 1, p. 1-382 382 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Targeting the population for gene therapy with MYBPC3
Carrier, L., 01.2021, In: J MOL CELL CARDIOL. 150, p. 101-108Research output: SCORING: Contribution to journal › SCORING: Review article › Research
A proteomics-based assessment of inflammation signatures in endotoxemia
Burnap, S. A., Mayr, U., Shankar-Hari, M., Cuello, F., Thomas, M. R., Shah, A. M., Sabroe, I., Storey, R. F. & Mayr, M., 2021, In: MOL CELL PROTEOMICS. 20, p. 100021Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Arginine:Glycine Amidinotransferase Is Essential for Creatine Supply in Mice During Chronic Hypoxia
Hannemann, J., Cordts, K., Seniuk, A., Choe, C-U., Schmidt-Hutten, L., Duque Escobar, J., Weinberger, F., Böger, R. & Schwedhelm, E., 2021, In: FRONT PHYSIOL. 12, p. 703069Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A Transgenic Mouse Model of Eccentric Left Ventricular Hypertrophy With Preserved Ejection Fraction Exhibits Alterations in the Autophagy-Lysosomal Pathway
Wenzel, K., Krämer, E., Geertz, B., Carrier, L., Felix, S. B., Könemann, S. & Schlossarek, S., 2021, In: FRONT PHYSIOL. 12, p. 614878Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Generation and characterization of human engineered heart tissue with a pharmacological off-on switch
Stüdemann, T., Manthey, C., Schulz, C., Köhne, M., Domke-Shibamiya, A., Penalosa Ruiz, G., Christ, T., Eschenhagen, T. & Weinberger, F., 2021, EMBO Workshop: Cardiomyocyte Biology.Research output: SCORING: Contribution to book/anthology › Conference contribution - Poster › Research
Generation of human engineered heart tissue with light activated ion channels
Stüdemann, T., Pan, B., Köhne, M., Bibra, C., Domke-Shibamiya, A., Stenzig, J., Eschenhagen, T. & Weinberger, F., 2021, Early Career Investigators pre-meeting Symposium at International Society for Heart Research- European Section.Research output: SCORING: Contribution to book/anthology › Conference contribution - Other conference contributions › Research
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
D. J. KLIONSKY ET AL., 2021, In: AUTOPHAGY.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2020
Intermittent optogenetic tachypacing of atrial engineered heart tissue induces only limited electrical remodelling
Lemoine, M. D., Lemme, M., Ulmer, B. M., Braren, I., Krasemann, S., Hansen, A., Kirchhof, P., Meyer, C., Eschenhagen, T. & Christ, T., 13.12.2020, In: J CARDIOVASC PHARM. 77, 3, p. 291-299 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes
Bojkova, D., Wagner, J. U. G., Shumliakivska, M., Aslan, G. S., Saleem, U., Hansen, A., Luxán, G., Günther, S., Pham, M. D., Krishnan, J., Harter, P. N., Ermel, U. H., Frangakis, A. S., Milting, H., Zeiher, A. M., Klingel, K., Cinatl, J., Dendorfer, A., Eschenhagen, T., Tschöpe, C., Ciesek, S. & Dimmeler, S., 01.12.2020, In: CARDIOVASC RES. 116, 14, p. 2207-2215 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Association of Previous Myocardial Infarction and Time to Presentation With Suspected Acute Myocardial Infarction
Troester, V., Strebel, I., Nestelberger, T., Boeddinghaus, J., Rubini, G. M., Lopez-Ayala, P., Koechlin, L., Glarner, N., Prepoudis, A., Miró, Ò. & APACE, I. ., 12.2020, In: J AM HEART ASSOC. 10, 1Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research