Research ExplorerScientific StaffAndreas Guse Publications

Prof.Dr.Dr. ID: 74033

Andreas Guse

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Publications

  1. 2019

  2. Correction: Culturing and patch clamping of Jurkat T cells and neurons on Al2O3 coated nanowire arrays of altered morphology

    Harberts, J., Zierold, R., Fendler, C., Koitmäe, A., Bayat, P., Fernandez-Cuesta, I., Loers, G., Diercks, B-P., Fliegert, R., Guse, A. H., Ronning, C., Otnes, G., Borgström, M. & Blick, R. H., 30.04.2019, In: RSC ADV. 9, 24, p. 13614

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Culturing and patch clamping of Jurkat T cells and neurons on Al2O3 coated nanowire arrays of altered morphology

    Harberts, J., Zierold, R., Fendler, C., Koitmäe, A., Bayat, P., Fernandez-Cuesta, I., Loers, G., Diercks, B-P., Fliegert, R., Guse, A. H., Ronning, C., Otnes, G., Borgström, M. & Blick, R. H., 09.04.2019, In: RSC ADV. 9, 20, p. 11194-11201 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation

    Fliegert, R., Heeren, J., Koch-Nolte, F., Nikolaev, V. O., Lohr, C., Meier, C. & Guse, A. H., 28.02.2019, In: BIOCHEM SOC T. 47, 1, p. 329-337 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  5. High-Resolution Calcium Imaging Method for Local Calcium Signaling

    Diercks, B-P., Werner, R., Schetelig, D., Wolf, I. & Guse, A., 2019, Calcium-Binding Proteins of the EF-Hand Superfamily. 1 ed. Humana Press, Vol. 1929. p. 27-39 13 p.

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review

  6. The Hamburg integrated medical degree program iMED

    Rheingans, A., Soulos, A., Mohr, S., Meyer, J. & Guse, A. H., 2019, In: GMS Journal for Medical Education. 36, 5, p. Doc52

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. 2018

  8. ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.

    Diercks, B-P., Werner, R., Weidemüller, P., Czarniak, F., Hernandez, L. C., Lehmann, C., Rosche, A., Krüger, A., Kaufmann, U., Vaeth, M., Failla, A., Zobiak, B., Kandil, F-I., Schetelig, D., Ruthenbeck, A., Meier, C., Lodygin, D., Flügel, A., Ren, D., Wolf, I., Feske, S. & Guse, A., 18.12.2018, In: SCIENCE SIGNALING. 11, 561, p. eaat0358

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Membrane-Permeable Octanoyloxybenzyl-Masked cNMPs As Novel Tools for Non-Invasive Cell Assays.

    Ruthenbeck, A., Marangoni, E., Diercks, B-P., Krüger, A., Froese, A., Bork, N., Nikolaev, V., Guse, A. & Meier, C., 13.11.2018, In: MOLECULES. 23, 11, p. E2960

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Small Molecule Antagonists of NAADP-Induced Ca Release in T-Lymphocytes Suggest Potential Therapeutic Agents for Autoimmune Disease

    Zhang, B., Watt, J. M., Cordiglieri, C., Dammermann, W., Mahon, M. F., Flügel, A., Guse, A. H. & Potter, B. V. L., 13.11.2018, In: SCI REP-UK. 8, 1, p. 16775

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. TRPM2 activation: Paradigm shifted?

    Fliegert, R., Hölzer, H. T. & Guse, A., 03.11.2018, In: CELL CALCIUM. S0143-4160

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  12. Medizinische Ausbildung in Bewegung

    Koch-Gromus, U., Guse, A. H. & van den Bussche, H., 02.2018, In: BUNDESGESUNDHEITSBLA. 61, 2, p. 129-131 3 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Modellstudiengänge in der Medizin

    Guse, A. & Kuhlmey, A., 02.2018, In: BUNDESGESUNDHEITSBLA. 61, 2, p. 132-140 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  14. Integration of nicotinic acid adenine dinucleotide phosphate (NAADP)-dependent calcium signalling

    Guse, A. & Diercks, B-P., 2018, In: J PHYSIOL-LONDON. 596, 14, p. 2735-2743

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. 2017

  16. Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+ tumors in mouse models in vivo

    Fumey, W., Koenigsdorf, J., Kunick, V., Menzel, S., Schütze, K., Unger, M., Schriewer, L., Haag, F., Adam, G., Oberle, A., Binder, M., Fliegert, R., Guse, A., Zhao, Y. J., Cheung Lee, H., Malavasi, F., Goldbaum, F., van Hegelsom, R., Stortelers, C., Bannas, P. & Koch-Nolte, F., 30.10.2017, In: SCI REP-UK. 7, 1, p. 14289

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. 2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist

    Fliegert, R., Bauche, A., Wolf Pérez, A-M., Watt, J. M., Rozewitz, M. D., Winzer, R., Janus, M., Gu, F., Rosche, A., Harneit, A., Flato, M., Moreau, C., Kirchberger, T., Wolters, V., Potter, B. V. L. & Guse, A. H., 09.2017, In: NAT CHEM BIOL. 13, 9, p. 1036-1044

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349

    Fliegert, R., Watt, J. M., Schöbel, A., Rozewitz, M., Moreau, C., Kirchberger, T., Thomas, M. P., Sick, W., Araujo, A. C., Harneit, A., Potter, B. V. L. & Guse, A., 16.06.2017, In: BIOCHEM J. 474, 13, p. 2159-2175

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Mag-Fluo4 in T cells: Imaging of intra-organelle free Ca(2+) concentrations

    Diercks, B-P., Fliegert, R. & Guse, A., 06.2017, In: BBA-MOL CELL RES. 1864, 6, p. 977-986

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Ca2+ Microdomains in T-Lymphocytes

    Wolf, I. & Guse, A., 02.05.2017, In: FRONT ONCOL.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  21. Ultra-fast cell counters based on microtubular waveguides

    Bausch, C., Heyn, C., Hansen, W., Wolf, I., Diercks, B-P., Guse, A. & Blick, R., 30.01.2017, In: SCI REP-UK. 7, 41584

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Systematic Analysis of Jurkat T-Cell Deformation in Fluorescence Microscopy Data

    Antoni, S-T., Ismail, O. M. F., Schetelig, D., Diercks, B-P., Werner, R., Wolf, I., Guse, A. & Schlaefer, A., 2017, Bildverarbeitung für die Medizin 2017: Algorithmen - Systeme - Anwendungen. Maier-Hain, K. H., Deserno, T., Handels, H. & Thomas, T. (eds.). 1 ed. Springer, p. 275-280 6 p. (Informatik aktuell).

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review

  23. 2016

  24. Ca(2+) microdomains, NAADP and type 1 ryanodine receptor in cell activation.

    Guse, A. & Wolf, I., 06.2016, In: BBA-MOL CELL RES. 1863, 6, p. 1379-1384

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Basic Principles of Science in Medical Education - Development and Implementation of a Two Week Introductory Track

    Vonneilich, N., Dubben, H-H., Kriston, L., Guse, A. H. & von dem Knesebeck, O., 01.05.2016, In: Creat Educ. 7, 6, p. 831-837

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Education › peer-review

  26. Exploring the value and role of integrated supportive science courses in the reformed medical curriculum iMED: a mixed methods study

    Eisenbarth, S., Tilling, T., Lueerss, E., Meyer, J., Sehner, S., Guse, A. & Guse, J., 29.04.2016, In: BMC MED EDUC. 16, p. 132

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Effects of Mentoring Speed Dating as an Innovative Matching Tool in Undergraduate Medical Education: A Mixed Methods Study

    Guse, J., Schweigert, E., Kulms, G., Heinen, I., Martens, C. & Guse, A., 09.02.2016, In: PLOS ONE. 11, 2, p. e0147444

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. 2015

  29. Frontrunners of T cell activation: Initial, localized Ca2+ signals mediated by NAADP and the type 1 ryanodine receptor

    Wolf, I. M. A., Diercks, B-P., Gattkowski, E., Czarniak, F., Kempski, J., Werner, R., Schetelig, D., Mittrücker, H-W., Schumacher, V., von Osten, M., Lodygin, D., Flügel, A., Fliegert, R. & Guse, A. H., 13.10.2015, In: SCI SIGNAL. 8, 398, p. Art. ra102 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Calcium mobilizing second messengers derived from NAD

    Guse, A. H., 01.09.2015, In: BBA-PROTEINS PROTEOM. 1854, 9, p. 1132-1137

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation

    Nebel, M., Zhang, B., Odoardi, F., Flügel, A., Potter, B. V. L. & Guse, A. H., 06.2015, In: Messenger (Los Angel). 4, 1, p. 104-111 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. A Modular Framework for Post-Processing and Analysis of Fluorescence Microscopy Image Sequences of Subcellular Calcium Dynamics

    Schetelig, D., Wolf, I., Diercks, B-P., Fliegert, R., Guse, A., Schlaefer, A. & Werner, R., 2015, Bildverarbeitung für die Medizin 2015. Handels, H., Deserno, T. M., Meinzer, H-P. & Tolxdorff, T. (eds.). 1 ed. Berlin Heidelberg: Springer, p. 401-406 6 p. (Informatik Aktuell).

    Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review

  33. 2014

  34. NAD derived second messengers: Role in spontaneous diastolic Ca(2+) transients

    Warszta, D., Nebel, M., Fliegert, R. & Guse, A. H., 01.11.2014, In: DNA REPAIR. 23, p. 69-78

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Speed mentoring: establishing successful mentoring relationships

    Kurré, J., Schweigert, E., Kulms, G. & Guse, A. H., 01.11.2014, In: MED EDUC. 48, 11, p. 1131

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  36. Design, Synthesis, and Chemical and Biological Properties of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose

    Tsuzuki, T., Takano, S., Sakaguchi, N., Kudoh, T., Murayama, T., Sakurai, T., Hashii, M., Higashida, H., Weber, K., Guse, A. H., Kameda, T., Hirokawa, T., Kumaki, Y., Arisawa, M., Potter, B. V. L. & Shuto, S., 01.06.2014, In: Messenger (Los Angel). 3, 1-2, p. 35-51 17 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. 2013

  38. Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists

    Moreau, C., Kirchberger, T., Swarbrick, J. M., Bartlett, S. J., Fliegert, R., Yorgan, T., Bauche, A., Harneit, A., Guse, A. H. & Potter, B. V. L., 27.12.2013, In: J MED CHEM. 56, 24, p. 10079-102 24 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. N-terminal tagging of two-pore channels interferes with NAADP action

    Guse, A. H., 01.07.2013, In: BIOCHEM J. 453, 1, p. e1-2

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  40. Design and synthesis of cyclic ADP-4-thioribose as a stable equivalent of cyclic ADP-ribose, a calcium ion-mobilizing second messenger

    Tsuzuki, T., Sakaguchi, N., Kudoh, T., Takano, S., Uehara, M., Murayama, T., Sakurai, T., Hashii, M., Higashida, H., Weber, K., Guse, A. H., Kameda, T., Hirokawa, T., Kumaki, Y., Potter, B. V. L., Fukuda, H., Arisawa, M. & Shuto, S., 24.06.2013, In: ANGEW CHEM INT EDIT. 52, 26, p. 6633-7 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Cycling assay for determining intracellular cyclic adp-ribose levels

    Bruzzone, S. & Guse, A. H., 01.06.2013, In: Cold Spring Harbor protocols. 2013, 6, p. 564-8 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Measuring Ca2+ release evoked by cyclic adp-ribose

    Guse, A. H., 01.06.2013, In: Cold Spring Harbor protocols. 2013, 6, p. 574-8 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Measuring CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) activity by reverse-phase HPLC

    Kirchberger, T. & Guse, A. H., 01.06.2013, In: Cold Spring Harbor protocols. 2013, 6, p. 569-73 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by β-adrenergic stimulation

    Nebel, M., Schwoerer, A. P., Warszta, D., Siebrands, C. C., Limbrock, A-C., Swarbrick, J. M., Fliegert, R., Weber, K., Bruhn, S., Hohenegger, M., Geisler, A., Herich, L., Schlegel, S., Carrier, L., Eschenhagen, T., Potter, B. V. L., Ehmke, H. & Guse, A. H., 31.05.2013, In: J BIOL CHEM. 288, 22, p. 16017-30 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling

    Wolf, I., Fliegert, R. & Guse, A. H., 01.01.2013, In: FRONT IMMUNOL. 4, p. 259

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. A mathematical model of T lymphocyte calcium dynamics derived from single transmembrane protein properties

    Schmeitz, C., Hernandez-Vargas, E. A., Fliegert, R., Guse, A. H. & Meyer-Hermann, M., 01.01.2013, In: FRONT IMMUNOL. 4, p. 277

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. NAADP signaling revisited

    Guse, A. H., Wolf, I. & Fliegert, R., 01.01.2013, In: CURR TOP MED CHEM. 13, 23, p. 2978-90 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. 2012

  49. Nicotinic Acid Adenine Dinucleotide 2'-Phosphate (NAADP) Binding Proteins in T-Lymphocytes

    Walseth, T. F., Lin-Moshier, Y., Weber, K., Marchant, J. S., Slama, J. T. & Guse, A. H., 01.06.2012, In: Messenger (Los Angel). 1, 1, p. 86-94 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells.

    Moreau, C., Kirchberger, T., Zhang, B., Thomas, M. P., Weber, K., Guse, A. H. & Potter, B. V. L., 2012, In: J MED CHEM. 55, 4, p. 1478-1489 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation.

    Schwarz, N., Drouot, L., Nicke, A., Fliegert, R., Boyer, O., Guse, A. H., Haag, F., Adriouch, S. & Koch-Nolte, F., 2012, In: PLOS ONE. 7, 7, p. 41269 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. Differential mentorship for medical students: development, implementation and initial evaluation

    Kurré, J., Bullinger, M., Petersen-Ewert, C. & Guse, A. H., 2012, In: INT J MED EDUC. 3, p. 216-224

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. Linking NAADP to ion channel activity: a unifying hypothesis.

    Guse, A. H. & Andreas, H., 2012, In: SCI SIGNAL. 5, 221, p. 18 221.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  54. Nicotinic Acid Adenine Dinucleotide 2-Phosphate (NAADP) Binding Proteins in T-Lymphocytes

    Walseth, T. F., Lin-Moshier, Y., Weber, K., Marchant, J. S., Slama, J. T. & Guse, A. H., 2012, In: Messenger. 1, 1, p. 86-94 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  55. Nicotinic acid adenine dinucleotide phosphate (NAADP) degradation by alkaline phosphatase.

    Schmid, F., Fliegert, R., Westphal, T., Bauche, A. & Guse, A. H., 2012, In: J BIOL CHEM. 287, 39, p. 32525-32534 39.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  56. 2011

  57. A novel membrane-permeant cADPR antagonist modified in the pyrophosphate bridge.

    Qi, N., Jung, K., Wang, M., Na, L. X., Yang, Z. J., Zhang, L. R., Guse, A. H. & Zhang, L. H., 2011, In: CHEM COMMUN. 47, 33, p. 9462-9464 33.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  58. CD38: a NAADP degrading enzyme.

    Schmid, F., Bruhn, S., Weber, K., Mittrücker, H. W. & Guse, A. H., 2011, In: FEBS LETT. 585, 22, p. 3544-3548 22.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  59. Synthesis of cyclic adenosine 5'-diphosphate ribose analogues: a C2'endo/syn "southern" ribose conformation underlies activity at the sea urchin cADPR receptor.

    Moreau, C., Ashamu, G. A., Bailey, V. C., Galione, A., Guse, A. H. & Potter, B. V. L., 2011, In: ORG BIOMOL CHEM. 9, 1, p. 278-290 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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