Department of Pediatric Hematology and Oncology
Publications
- 2024
Reintegration into school, kindergarten and work in families of childhood cancer survivors after a family-oriented rehabilitation program
Inhestern, L., Nasse, M. L., Krauth, K. A., Kandels, D., Rutkowski, S., Escherich, G. & Bergelt, C., 07.03.2024, In: FRONT PEDIATR. 12, p. 1288567Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A Multimodal Lifestyle Psychosocial Survivorship Program in Young Cancer Survivors: The CARE for CAYA Program-A Randomized Clinical Trial Embedded in a Longitudinal Cohort Study
von Grundherr, J., Elmers, S., Koch, B., Hail, L-A., Mann, J., Escherich, G., Bergelt, C., Samland, L., Jensen, W., Vettorazzi, E., Stark, M., Valentini, L., Baumann, F. T., Singer, S., Reer, R., Beller, R., Calaminus, G., Faber, J., Classen, C. F., Gebauer, J., Hilgendorf, I., Koehler, M., Puzik, A., Salzmann, N., Sander, A., Schiffmann, L., Sokalska-Duhme, M., Schuster, S., Kock-Schoppenhauer, A-K., Bokemeyer, C., Sinn, M., Stein, A., Dwinger, S. & Salchow, J., 04.03.2024, In: JAMA NETW OPEN. 7, 3, p. e242375Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular refinement of pilocytic astrocytoma in adult patients
Bode, H., Kresbach, C., Holdhof, D., Dorostkar, M. M., Harter, P. N., Hench, J., Frank, S., Suwala, A. K., Schweizer, L., Eckhardt, A., Neyazi, S., Bockmayr, M., Wefers, A. K. & Schüller, U., 02.2024, In: NEUROPATH APPL NEURO. 50, 1, p. e12949Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation
Neyazi, S., Yamazawa, E., Hack, K., Tanaka, S., Nagae, G., Kresbach, C., Umeda, T., Eckhardt, A., Tatsuno, K., Pohl, L., Hana, T., Bockmayr, M., Kim, P., Dorostkar, M. M., Takami, T., Obrecht, D., Takai, K., Suwala, A. K., Komori, T., Godbole, S., Wefers, A. K., Otani, R., Neumann, J. E., Higuchi, F., Schweizer, L., Nakanishi, Y., Monoranu, C-M., Takami, H., Engertsberger, L., Yamada, K., Ruf, V., Nomura, M., Mohme, T., Mukasa, A., Herms, J., Takayanagi, S., Mynarek, M., Matsuura, R., Lamszus, K., Ishii, K., Kluwe, L., Imai, H., von Deimling, A., Koike, T., Benesch, M., Kushihara, Y., Snuderl, M., Nambu, S., Frank, S., Omura, T., Hagel, C., Kugasawa, K., Mautner, V. F., Ichimura, K., Rutkowski, S., Aburatani, H., Saito, N. & Schüller, U., 24.01.2024, In: ACTA NEUROPATHOL. 147, 1, p. 22Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma
Drexler, R., Khatri, R., Schüller, U., Eckhardt, A., Ryba, A., Sauvigny, T., Dührsen, L., Mohme, M., Ricklefs, T., Bode, H., Hausmann, F., Huber, T. B., Bonn, S., Voß, H., Neumann, J. E., Silverbush, D., Hovestadt, V., Suvà, M. L., Lamszus, K., Gempt, J., Westphal, M., Heiland, D. H., Hänzelmann, S. & Ricklefs, F. L., 20.01.2024, In: ACTA NEUROPATHOL. 147, 1, p. 21Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct clinicopathological and molecular features
Dottermusch, M., Ryba, A., Ricklefs, F. L., Flitsch, J., Schmid, S., Glatzel, M., Saeger, W., Neumann, J. E. & Schüller, U., 16.01.2024, In: ACTA NEUROPATHOL. 147, 1, p. 16Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Unclassifiable CNS tumors in DNA methylation-based classification: clinical challenges and prognostic impact
Drexler, R., Brembach, F., Sauvigny, J., Ricklefs, F. L., Eckhardt, A., Bode, H., Gempt, J., Lamszus, K., Westphal, M., Schüller, U. & Mohme, M., 16.01.2024, In: ACTA NEUROPATHOL COM. 12, 1, p. 9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
And what about today? Burden and support needs of adolescent childhood cancer survivors in long-term follow-up care-A qualitative content analysis
Winzig, J., Inhestern, L., Sigmund, D., Paul, V., Hail, L-A., Rutkowski, S., Escherich, G. & Bergelt, C., 01.2024, In: CHILD CARE HLTH DEV. 50, 1, p. e13207Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Child-centredness in paediatric magnetic resonance imaging: Information needs and experiences of children requiring magnetic resonance imaging and their parents
Inhestern, L., Herrmann, J., Schürmann, J., Meister, R. L., Nawka, M. T., Mynarek, M., Linhart, D. & Bergelt, C., 01.2024, In: CHILD CARE HLTH DEV. 50, 1, p. e13157Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome
Kolodziejczak, A. S., Guerrini-Rousseau, L., Planchon, J. M., Ecker, J., Selt, F., Mynarek, M., Obrecht, D., Sill, M., Autry, R. J., Zhao, E., Hirsch, S., Amouyal, E., Dufour, C., Ayrault, O., Torrejon, J., Waszak, S. M., Ramaswamy, V., Pentikainen, V., Demir, H. A., Clifford, S. C., Schwalbe, E. C., Massimi, L., Snuderl, M., Galbraith, K., Karajannis, M. A., Hill, K., Li, B. K., Walsh, M., White, C. L., Redmond, S., Loizos, L., Jakob, M., Kordes, U. R., Schmid, I., Hauer, J., Blattmann, C., Filippidou, M., Piccolo, G., Scheurlen, W., Farrag, A., Grund, K., Sutter, C., Pietsch, T., Frank, S., Schewe, D. M., Malkin, D., Ben-Arush, M., Sehested, A., Wong, T-T., Wu, K-S., Liu, Y-L., Carceller, F., Mueller, S., Stoller, S., Taylor, M. D., Tabori, U., Bouffet, E., Kool, M., Sahm, F., von Deimling, A., Korshunov, A., von Hoff, K., Kratz, C. P., Sturm, D., Jones, D. T. W., Rutkowski, S., van Tilburg, C. M., Witt, O., Bougeard, G., Pajtler, K. W., Pfister, S. M., Bourdeaut, F. & Milde, T., 08.12.2023, In: NEURO-ONCOLOGY. 25, 12, p. 2273-2286 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Development of a centralised triage centre for children with cancer and blood disorders in response to the humanitarian crisis in Ukraine
Salek, M., Mueller, A., Alanbousi, I., Cepowska, Z., Dutkiewicz, M., Earl, J., Evseev, D., Kizyma, R., Kliuchkivska, K., Kolodrubiec, J., Matczak, K., Nogovitsyna, Y., Oszer, A., Pogorelyy, M., Raciborska, A., Rasul, S., Sokolowski, I., Sopilnyak, A., Vinitsky, A., Wlodarski, M. W., Wobst, N., Yakimkova, T., Rodriguez-Galindo, C., Wise, P. H., Mlynarski, W., Agulnik, A. & SAFER Ukraine Collaborative, 12.2023, In: LANCET ONCOL. 24, 12, p. 1315-1318 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Solid pseudopapillary neoplasms of the pancreas in childhood and adolescence-an analysis of the German Registry for Rare Pediatric Tumors (STEP)
Jentzsch, C., Fuchs, J., Agaimy, A., Vokuhl, C., Escherich, G., Blattmann, C., Warmann, S. W., Schmidt, A., Schäfer, J., Brecht, I. B., Schneider, D. T. & Abele, M., 12.2023, In: EUR J PEDIATR. 182, 12, p. 5341-5352 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures
Schoof, M., Godbole, S., Albert, T. K., Dottermusch, M., Walter, C., Ballast, A., Qin, N., Olivera, M. B., Göbel, C., Neyazi, S., Holdhof, D., Kresbach, C., Peter, L-S., Epplen, G. D., Thaden, V., Spohn, M., Blattner-Johnson, M., Modemann, F., Mynarek, M., Rutkowski, S., Sill, M., Varghese, J., Afflerbach, A-K., Eckhardt, A., Münter, D., Verma, A., Struve, N., Jones, D. T. W., Remke, M., Neumann, J. E., Kerl, K. & Schüller, U., 24.11.2023, In: NAT COMMUN. 14, 1, p. 7717Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Phase II Trial of Dabrafenib Plus Trametinib in Relapsed/Refractory BRAF V600–Mutant Pediatric High-Grade Glioma
Hargrave, D. R., Terashima, K., Hara, J., Kordes, U., Upadhyaya, S., Sahm, F., Bouffet, E., Packer, R. J., Witt, O., Sandalic, L., Kieloch, A., Russo, M. & Cohen, K., 20.11.2023, In: J CLIN ONCOL. 41, 33, p. 5174-5183 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Outcome for Children and Young Adults With T-Cell ALL and Induction Failure in Contemporary Trials
Raetz, E. A., Rebora, P., Conter, V., Schrappe, M., Devidas, M., Escherich, G., Imai, C., De Moerloose, B., Schmiegelow, K., Burns, M. A., Elitzur, S., Pieters, R., Attarbaschi, A., Yeoh, A., Pui, C-H., Stary, J., Cario, G., Bodmer, N., Moorman, A. V., Buldini, B., Vora, A. & Valsecchi, M. G., 10.11.2023, In: J CLIN ONCOL. 41, 32, p. 5025-5034 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice
Göbel, C., Godbole, S., Schoof, M., Holdhof, D., Kresbach, C., Loose, C., Neumann, J. & Schüller, U., 02.11.2023, In: ACTA NEUROPATHOL COM. 11, 1, p. 174Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Th1 cytokines in pediatric acute lymphoblastic leukemia
Schober, S., Rottenberger, J. M., Hilz, J., Schmid, E., Ebinger, M., Feuchtinger, T., Handgretinger, R., Lang, P. & Queudeville, M., 11.2023, In: CANCER IMMUNOL IMMUN. 72, 11, p. 3621-3634 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Health-Related Quality of Life and Mental Health of Children with Embryonal Abdominal Tumors
Behrendt, P., Boettcher, M., Zierke, K. T., Najem, S., Zapf, H., Reinshagen, K., Wößmann, W. & Boettcher, J., 23.10.2023, In: CHILDREN-BASEL. 10, 10, 1720.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multimodal cartography of human lymphopoiesis reveals B and T/NK/ILC lineages are subjected to differential regulation
Alhaj Hussen, K., Chabaane, E., Nelson, E., Lekiashvili, S., Diop, S., Keita, S., Evrard, B., Lardenois, A., Delord, M., Verhoeyen, E., Cornils, K., Kasraian, Z., Macintyre, E. A., Cumano, A., Garrick, D., Goodhardt, M., Andrieu, G. P., Asnafi, V., Chalmel, F. & Canque, B., 20.10.2023, In: ISCIENCE. 26, 10, 107890.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rhabdoid tumors in patients conceived following ART: is there an association?
Nemes, K., Benesch, M., Kolarova, J., Johann, P., Hasselblatt, M., Thomas, C., Bens, S., Glaser, S., Ammerpohl, O., Liaugaudiene, O., Sadeghipour, A., von der Weid, N., Schmid, I., Gidding, C., Erdreich-Epstein, A., Khurana, C., Ebetsberger-Dachs, G., Lemmer, A., Khatib, Z., Hernández Marqués, C., Pears, J., Quehenberger, F., Kordes, U., Vokuhl, C., Gerss, J., Schwarz, H., Bison, B., Biegel, J. A., Siebert, R. & Frühwald, M. C., 03.10.2023, In: HUM REPROD. 38, 10, p. 2028-2038 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ABL-class Genomic Breakpoint Q-PCR: A Patient-specific Approach for MRD Monitoring in Acute Lymphoblastic Leukemia
van Outersterp, I., van der Velden, V. H. J., Hoogeveen, P. G., Vaitkevičienė, G. E., Sonneveld, E., van Haaften, G., Kuiper, R. P., Zur Stadt, U., Escherich, G., Boer, J. M. & den Boer, M. L., 10.2023, In: HEMASPHERE. 7, 10, p. e967Research output: SCORING: Contribution to journal › Letter › Research › peer-review
Activated phosphoinositide 3-kinase δ syndrome: Update from the ESID Registry and comparison with other autoimmune-lymphoproliferative inborn errors of immunity
Maccari, M. E., Wolkewitz, M., Schwab, C., Lorenzini, T., Leiding, J. W., Aladjdi, N., Abolhassani, H., Abou-Chahla, W., Aiuti, A., Azarnoush, S., Baris, S., Barlogis, V., Barzaghi, F., Baumann, U., Bloomfield, M., Bohynikova, N., Bodet, D., Boutboul, D., Bucciol, G., Buckland, M. S., Burns, S. O., Cancrini, C., Cathébras, P., Cavazzana, M., Cheminant, M., Chinello, M., Ciznar, P., Coulter, T. I., D'Aveni, M., Ekwall, O., Eric, Z., Eren, E., Fasth, A., Frange, P., Fournier, B., Garcia-Prat, M., Gardembas, M., Geier, C., Ghosh, S., Goda, V., Hammarström, L., Hauck, F., Heeg, M., Heropolitanska-Pliszka, E., Hilfanova, A., Jolles, S., Karakoc-Aydiner, E., Kindle, G. R., Kiykim, A., Klemann, C., Koletsi, P., Koltan, S., Kondratenko, I., Körholz, J., Krüger, R., Jeziorski, E., Levy, R., Le Guenno, G., Lefevre, G., Lougaris, V., Marzollo, A., Mahlaoui, N., Malphettes, M., Meinhardt, A., Merlin, E., Meyts, I., Milota, T., Moreira, F., Moshous, D., Mukhina, A., Neth, O., Neubert, J., Neven, B., Nieters, A., Nove-Josserand, R., Oksenhendler, E., Ozen, A., Olbrich, P., Perlat, A., Pac, M., Schmid, J. P., Pacillo, L., Parra-Martinez, A., Paschenko, O., Pellier, I., Sefer, A. P., Plebani, A., Plantaz, D., Prader, S., Raffray, L., Ritterbusch, H., Riviere, J. G., Rivalta, B., Rusch, S., Sakovich, I., Savic, S., Scheible, R., Schleinitz, N., Schuetz, C., Schulz, A., Sediva, A., Semeraro, M., Sharapova, S. O., Shcherbina, A., Slatter, M. A., Sogkas, G., Soler-Palacin, P., Speckmann, C., Stephan, J-L., Suarez, F., Tommasini, A., Trück, J., Uhlmann, A., van Aerde, K. J., van Montfrans, J., von Bernuth, H., Warnatz, K., Williams, T., Worth, A. J. J., Ip, W., Picard, C., Catherinot, E., Nademi, Z., Grimbacher, B., Forbes Satter, L. R., Kracker, S., Chandra, A., Condliffe, A. M., Ehl, S. & European Society for Immunodeficiencies Registry Working Party, 10.2023, In: J ALLERGY CLIN IMMUN. 152, 4, p. 984-996.e10Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epigenetic profiling reveals a strong association between lack of 5-ALA fluorescence and EGFR amplification in IDH-wildtype glioblastoma
Drexler, R., Sauvigny, T., Schüller, U., Eckhardt, A., Maire, C. L., Khatri, R., Hausmann, F., Hänzelmann, S., Huber, T. B., Bonn, S., Bode, H., Lamszus, K., Westphal, M., Dührsen, L. & Ricklefs, F. L., 10.2023, In: NEURO-ONCOL PRACT. 10, 5, p. 462-471 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Parent-reported health-related quality of life in pediatric childhood cancer survivors and factors associated with poor health-related quality of life in aftercare
Winzig, J., Inhestern, L., Paul, V., Nasse, M. L., Krauth, K. A., Kandels, D., Rutkowski, S., Escherich, G. & Bergelt, C., 10.2023, In: QUAL LIFE RES. 32, 10, p. 2965-2974 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
hGFAP-mediated GLI2 overexpression leads to early death and severe cerebellar malformations with rare tumor formation
Niesen, J., Hermans-Borgmeyer, I., Krüger, C., Schoof, M., Modemann, F. & Schüller, U., 15.09.2023, In: ISCIENCE. 26, 9, p. 107501Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Atypical Neurofibromas reveal distinct epigenetic features with proximity to benign peripheral nerve sheath tumor entities
Kresbach, C., Dottermusch, M., Eckhardt, A., Ristow, I., Paplomatas, P., Altendorf, L., Wefers, A. K., Bockmayr, M., Belakhoua, S., Tran, I., Pohl, L., Neyazi, S., Bode, H., Farschtschi, S., Well, L., Friedrich, R. E., Reuss, D., Snuderl, M., Hagel, C., Mautner, V-F. & Schüller, U., 05.09.2023, In: NEURO-ONCOLOGY. 25, 9, p. 1644-1655 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics
Johann, P. D., Altendorf, L., Efremova, E-M., Holsten, T., Steinbügl, M., Nemes, K., Eckhardt, A., Kresbach, C., Bockmayr, M., Koch, A., Haberler, C., Antonelli, M., DeSisto, J., Schuhmann, M. U., Hauser, P., Siebert, R., Bens, S., Kool, M., Green, A. L., Hasselblatt, M., Frühwald, M. C. & Schüller, U., 09.2023, In: ACTA NEUROPATHOL. 146, 3, p. 527-541 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability
Drexler, R., Khatri, R., Sauvigny, T., Mohme, M., Maire, C. L., Ryba, A., Zghaibeh, Y., Dührsen, L., Salviano-Silva, A., Lamszus, K., Westphal, M., Gempt, J., Wefers, A. K., Neumann, J., Bode, H., Hausmann, F., Huber, T. B., Bonn, S., Jütten, K., Delev, D., Weber, K. J., Harter, P. N., Onken, J., Vajkoczy, P., Capper, D., Wiestler, B., Weller, M., Snijder, B., Buck, A., Weiss, T., Keough, M. B., Ni, L., Monje, M., Silverbush, D., Hovestadt, V., Suvà, M. L., Krishna, S., Hervey-Jumper, S. L., Schüller, U., Heiland, D. H., Hänzelmann, S. & Ricklefs, F. L., 07.08.2023, In: bioRxiv.Research output: SCORING: Contribution to journal › Preprint › Research
Risk prediction in early childhood sonic hedgehog medulloblastoma treated with radiation-avoiding chemotherapy
Tonn, S., Korshunov, A., Obrecht, D., Sill, M., Spohn, M., von Hoff, K., Milde, T., Pietsch, T., Goschzik, T., Bison, B., Juhnke, B-O., Struve, N., Sturm, D., Sahm, F., Bockmayr, M., Friedrich, C., von Bueren, A. O., Gerber, N. U., Benesch, M., Jones, D. T. W., Kool, M., Wefers, A. K., Schüller, U., Pfister, S. M., Rutkowski, S. & Mynarek, M., 03.08.2023, In: NEURO-ONCOLOGY. 25, 8, p. 1518-1529 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rapid Determination of Nutmeg Shell Content in Ground Nutmeg Using FT-NIR Spectroscopy and Machine Learning
Drees, A., Bockmayr, B., Bockmayr, M. & Fischer, M., 02.08.2023, In: FOODS. 12, 15, 2939.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Emotional and behavioral problems of pediatric cancer survivors and their siblings: Concordance of child self-report and parent proxy-report
Paul, V., Inhestern, L., Winzig, J., Nasse, M. L., Krauth, K. A., Rutkowski, S., Escherich, G. & Bergelt, C., 08.2023, In: PSYCHO-ONCOLOGY. 32, 8, p. 1248-1256 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Glyco-binding domain chimeric antigen receptors as a new option for cancer immunotherapy
Franke, A-K., Wessolowski, C., Thaden, V., Müller, I. & Cornils, K., 08.2023, In: GENE THER. 30, 7-8, p. 603-611 9 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Mitochondrial DNA mutations in Medulloblastoma
Funke, V. L. E., Sandmann, S., Melcher, V., Seggewiss, J., Horvath, J., Jäger, N., Kool, M., Jones, D. T. W., Pfister, S. M., Milde, T., Rutkowski, S., Mynarek, M., Varghese, J., Sträter, R., Rust, S., Seelhöfer, A., Reunert, J., Fiedler, B., Schüller, U., Marquardt, T. & Kerl, K., 27.07.2023, In: ACTA NEUROPATHOL COM. 11, 1, p. 124Research output: SCORING: Contribution to journal › Case report › Research › peer-review
Reduced Humoral and Cellular Immune Response to Primary COVID-19 mRNA Vaccination in Kidney Transplanted Children Aged 5–11 Years
Lalia, J. K., Schild, R-S., Lütgehetmann, M., Dunay, G. A., Kallinich, T., Kobbe, R., Massoud, M., Oh, J., Pietzsch, L., Schulze-Sturm, U., Schuetz, C., Sibbertsen, F., Speth, F., Thieme, S., Witkowski, M., Berner, R., Muntau, A. C., Gersting, S. W., Toepfner, N., Pagel, J. & Paul, K., 14.07.2023, In: VIRUSES-BASEL. 15, 7, p. 1553Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adult intracranial ependymoma-relevance of DNA methylation profiling for diagnosis, prognosis, and treatment
Träger, M., Schweizer, L., Pérez, E., Schmid, S., Hain, E. G., Dittmayer, C., Onken, J., Fukuoka, K., Ichimura, K., Schüller, U., Dührsen, L., Müther, M., Paulus, W., Thomas, C., Gutt-Will, M., Schucht, P., Maragkou, T., Schittenhelm, J., Eckert, F., Niyazi, M., Fleischmann, D. F., Dorostkar, M. M., Feyer, P., May, S-A., Moskopp, D., Badakhshi, H., Radke, C., Walter, J., Ehret, F., Capper, D. & Kaul, D., 06.07.2023, In: NEURO-ONCOLOGY. 25, 7, p. 1286-1298 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SHIP1 Is Present but Strongly Downregulated in T-ALL, and after Restoration Suppresses Leukemia Growth in a T-ALL Xenotransplantation Mouse Model
Ehm, P., Rietow, R., Wegner, W., Bußmann, L., Kriegs, M., Dierck, K., Horn, S., Streichert, T., Horstmann, M. & Jücker, M., 06.07.2023, In: CELLS-BASEL. 12, 13, p. 1798Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The tumor suppressor CREBBP and the oncogene MYCN cooperate to induce malignant brain tumors in mice
Schoof, M., Epplen, G. D., Walter, C., Ballast, A., Holdhof, D., Göbel, C., Neyazi, S., Varghese, J., Albert, T. K., Kerl, K. & Schüller, U., 05.07.2023, In: ONCOGENESIS. 12, 1, p. 36Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prospective Newborn Screening for SCID in Germany: A First Analysis by the Pediatric Immunology Working Group (API)
Speckmann, C., Nennstiel, U., Hönig, M., Albert, M. H., Ghosh, S., Schuetz, C., Brockow, I., Hörster, F., Niehues, T., Ehl, S., Wahn, V., Borte, S., Lehmberg, K., Baumann, U., Beier, R., Krüger, R., Bakhtiar, S., Kuehl, J-S., Klemann, C., Kontny, U., Holzer, U., Meinhardt, A., Morbach, H., Naumann-Bartsch, N., Rothoeft, T., Kreins, A. Y., Davies, E. G., Schneider, D. T., Bernuth, H. V., Klingebiel, T., Hoffmann, G. F., Schulz, A. & Hauck, F., 07.2023, In: J CLIN IMMUNOL. 43, 5, p. 965-978 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Group-specific cellular metabolism in Medulloblastoma
Funke, V. L. E., Walter, C., Melcher, V., Wei, L., Sandmann, S., Hotfilder, M., Varghese, J., Jäger, N., Kool, M., Jones, D. T. W., Pfister, S. M., Milde, T., Mynarek, M., Rutkowski, S., Seggewiss, J., Jeising, D., de Faria, F. W., Marquardt, T., Albert, T. K., Schüller, U. & Kerl, K., 05.06.2023, In: J TRANSL MED. 21, 1, p. 363Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Generalized Infantile Myofibromatosis with Extensive Small Bowel Involvement in a Neonate
Schubert, J. P., Wößmann, W., Königs, I., Clauditz, T., Kordes, U. & Reinshagen, K., 06.2023, In: Z GEBURTSH NEONATOL. 227, 3, p. 231-235 5 p.Research output: SCORING: Contribution to journal › Case report › Research › peer-review
Long-term sequelae after immunotherapeutic approaches in haematological malignancies-what do we know?
Escherich, G. & Hough, R., 06.2023, In: LANCET HAEMATOL. 10, 6, p. e395-e396Research output: SCORING: Contribution to journal › Comment/debate › Research
Preclinical patient-derived modeling of castration-resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease
Elsesy, M. E., Oh-Hohenhorst, S. J., Oing, C., Eckhardt, A., Burdak-Rothkamm, S., Alawi, M., Müller, C., Schüller, U., Maurer, T., von Amsberg, G., Petersen, C., Rothkamm, K. & Mansour, W. Y., 06.2023, In: MOL ONCOL. 17, 6, p. 1129-1147 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes
Korshunov, A., Okonechnikov, K., Schrimpf, D., Tonn, S., Mynarek, M., Koster, J., Sievers, P., Milde, T., Sahm, F., Jones, D. T. W., von Deimling, A., Pfister, S. M. & Kool, M., 06.2023, In: ACTA NEUROPATHOL. 145, 6, p. 829-842 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Kinder und Jugendliche mit intrakraniellem Ependymom – Empfehlungen der HIT-MED-Studiengruppe der GPOH zur Erstlinientherapie
Obrecht, D., Mynarek, M., Stickan-Verfürth, M., Bison, B., Schüller, U., Pajtler, K., Hagel, C., Thomale, U-W., Fleischhack, G., Timmermann, B. & Rutkowski, S., 12.05.2023, In: KLIN PADIATR. 235, 3, p. 167-177 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeted anticonvulsive treatment of IDH-wildtype glioblastoma based on DNA methylation subclasses
Drexler, R., Göttsche, J., Sauvigny, T., Schüller, U., Khatri, R., Hausmann, F., Hänzelmann, S., Huber, T. B., Bonn, S., Heiland, D. H., Delev, D., Venkataramani, V., Winkler, F., Weller, J., Zeyen, T., Herrlinger, U., Gempt, J., Ricklefs, F. L. & Dührsen, L., 04.05.2023, In: NEURO-ONCOLOGY. 25, 5, p. 1006-1008 3 p.Research output: SCORING: Contribution to journal › Letter › Research › peer-review
Combination therapy with crizotinib and vinblastine for relapsed or refractory pediatric ALK-positive anaplastic large cell lymphoma
Knörr, F., Schellekens, K. P. J., Schoot, R. A., Landman-Parker, J., Teltschik, H-M., Förster, J., Riquelme, A., Huitema, A. D. R., Van Eijkelenburg, N. K. A., Beishuizen, A., Zwaan, C. M., Woessmann, W. & Van der Lugt, J., 01.05.2023, In: HAEMATOLOGICA. 108, 5, p. 1442-1446 5 p.Research output: SCORING: Contribution to journal › Letter › Research › peer-review
Evaluating the safety of perioperative dexamethasone treatment: A retrospective analysis of a single center pediatric low-grade glioma cohort
Gorodezki, D., Zipfel, J., Queudeville, M., Holzer, U., Bevot, A., Schittenhelm, J., Nägele, T., Schuhmann, M. U. & Ebinger, M., 01.05.2023, In: INT J CANCER. 152, 9, p. 1875-1883 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Antimicrobial use in pediatric oncology and hematology in Germany and Austria, 2020/2021: a cross-sectional, multi-center point-prevalence study with a multi-step qualitative adjudication process
Papan, C., Reifenrath, K., Last, K., Attarbaschi, A., Graf, N., Groll, A. H., Hübner, J., Laws, H-J., Lehrnbecher, T., Liese, J. G., Martin, L., Tenenbaum, T., Vieth, S., von Both, U., Wagenpfeil, G., Weichert, S., Hufnagel, M., Simon, A. & AB-PPS PedOnc Study Group, 05.2023, In: LANCET REG HEALTH-EU. 28, p. 100599Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Correction: Impact of COVID-19 Related Restrictions on Infections in Children with Cancer or after Hematopoietic SCT
Hauch, R., Hinrichs, M., Ruhwald, R., Schrum, J., Rutkowski, S., Woessmann, W. & Winkler, B., 05.2023, In: KLIN PADIATR. 235, 3, p. e1-e2Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Generation of new transgenic SMARCA4-deficient mouse models results in neuromuscular weakness and paralysis of limbs
Neyazi, S., Altendorf, L., Schwetje, D., Göbel, C., Schoof, M., Holdhof, D. & Schüller, U., 05.2023, In: BRAIN PATHOL. 33, 3, p. e13146Research output: SCORING: Contribution to journal › Letter › Research › peer-review
Impact of COVID-19 Related Restrictions on Infections in Children with Cancer or after Hematopoietic SCT: A Monocentric, Retrospective Study
Hauch, R., Hinrichs, M., Ruhwald, R., Schrum, J., Rutkowski, S., Woessmann, W. & Winkler, B., 05.2023, In: KLIN PADIATR. 235, 3, p. 159-166 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Isolated extradural sacrococcygeal ependymoma mimicking teratoma in a 5-year-old boy
Claviez, A., Moritz, J. D., Yuan, M., Vieth, S., Bergholz, R., Ahmeti, H. & Schüller, U., 05.2023, In: KLIN PADIATR. 235, 3, p. 185-187 3 p.Research output: SCORING: Contribution to journal › Case report › Research › peer-review
Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification
Goddard, J., Castle, J., Southworth, E., Fletcher, A., Crosier, S., Martin-Guerrero, I., García-Ariza, M., Navajas, A., Masliah-Planchon, J., Bourdeaut, F., Dufour, C., Ayrault, O., Goschzik, T., Pietsch, T., Sill, M., Pfister, S. M., Rutkowski, S., Richardson, S., Hill, R. M., Williamson, D., Bailey, S., Schwalbe, E. C., Clifford, S. C. & Hicks, D., 05.2023, In: ACTA NEUROPATHOL. 145, 5, p. 651-666 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiple sclerosis, disease-modifying drugs and risk for adverse perinatal and pregnancy outcomes: Results from a population-based cohort study
Fink, K., Gorczyca, A., Alping, P., Englund, S., Farmand, S., Langer-Gould, A. M., Piehl, F., McKay, K., Frisell, T. & Razaz, N., 05.2023, In: MULT SCLER J. 29, 6, p. 731-740 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Prognostic Effect of IKZF1 Deletions in ETV6::RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia
Østergaard, A., Enshaei, A., Pieters, R., Vora, A., Horstmann, M. A., Escherich, G., Johansson, B., Heyman, M., Schmiegelow, K., Hoogerbrugge, P. M., den Boer, M. L., Kuiper, R. P., Moorman, A. V., Boer, J. M. & van Leeuwen, F. N., 05.2023, In: HEMASPHERE. 7, 5, p. e875Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blinatumomab Added to Chemotherapy in Infant Lymphoblastic Leukemia
van der Sluis, I. M., de Lorenzo, P., Kotecha, R. S., Attarbaschi, A., Escherich, G., Nysom, K., Stary, J., Ferster, A., Brethon, B., Locatelli, F., Schrappe, M., Scholte-van Houtem, P. E., Valsecchi, M. G. & Pieters, R., 27.04.2023, In: NEW ENGL J MED. 388, 17, p. 1572-1581 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MAP kinase activating death domain deficiency is a novel cause of impaired lymphocyte cytotoxicity
Schütze, K., Groß, M., Cornils, K., Wustrau, K., Schneppenheim, S., Lenhartz, H., Korenke, G-C., Janka, G., Ledig, S., Müller, I., Ehl, S. & Lehmberg, K., 25.04.2023, In: BLOOD ADV. 7, 8, p. 1531-1535 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Elevated RIPK3 correlates with disease burden in myelofibrosis
Dill, V., Wagner, C. V., Keller, E. C., Fernandez-Hernandez, F. J., Shoumariyeh, K., Odinius, T. O., Buschhorn, L., Hauch, R. T., Suren, C., Hecker, J. S., Herhaus, P., Sandherr, M., Schmidt, B., Slotta-Huspenina, J., Bassermann, F., Höckendorf, U., Jilg, S., Branca, C., Vosberg, S. & Jost, P. J., 11.04.2023, In: BLOOD ADV. 7, 7, p. 1219-1224 6 p.Research output: SCORING: Contribution to journal › Letter › Research
Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study
Erker, C., Mynarek, M., Bailey, S., Mazewski, C. M., Baroni, L., Massimino, M., Hukin, J., Aguilera, D., Cappellano, A. M., Ramaswamy, V., Lassaletta, A., Perreault, S., Kline, C. N., Rajagopal, R., Michaiel, G., Zapotocky, M., Santa-Maria Lopez, V., La Madrid, A. M., Cacciotti, C., Sandler, E. S., Hoffman, L. M., Klawinski, D., Khan, S., Salloum, R., Hoppmann, A. L., Larouche, V., Dorris, K., Toledano, H., Gilheeney, S. W., Abdelbaki, M. S., Wilson, B., Tsang, D. S., Knipstein, J., Oren, M. Y., Shah, S., Murray, J. C., Ginn, K. F., Wang, Z. J., Fleischhack, G., Obrecht, D., Tonn, S., Harrod, V. L., Matheson, K., Crooks, B., Strother, D. R., Cohen, K. J., Hansford, J. R., Mueller, S., Margol, A., Gajjar, A., Dhall, G., Finlay, J. L., Northcott, P. A., Rutkowski, S., Clifford, S. C., Robinson, G., Bouffet, E. & Lafay-Cousin, L., 01.04.2023, In: J CLIN ONCOL. 41, 10, p. 1921-1932 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology
Sturm, D., Capper, D., Andreiuolo, F., Gessi, M., Kölsche, C., Reinhardt, A., Sievers, P., Wefers, A. K., Ebrahimi, A., Suwala, A. K., Gielen, G. H., Sill, M., Schrimpf, D., Stichel, D., Hovestadt, V., Daenekas, B., Rode, A., Hamelmann, S., Previti, C., Jäger, N., Buchhalter, I., Blattner-Johnson, M., Jones, B. C., Warmuth-Metz, M., Bison, B., Grund, K., Sutter, C., Hirsch, S., Dikow, N., Hasselblatt, M., Schüller, U., Gerber, N. U., White, C. L., Buntine, M. K., Kinross, K., Algar, E. M., Hansford, J. R., Gottardo, N. G., Hernáiz Driever, P., Gnekow, A., Witt, O., Müller, H. L., Calaminus, G., Fleischhack, G., Kordes, U., Mynarek, M., Rutkowski, S., Frühwald, M. C., Kramm, C. M., von Deimling, A., Pietsch, T., Sahm, F., Pfister, S. M. & Jones, D. T. W., 04.2023, In: NAT MED. 29, 4, p. 917-926 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo
Genduso, S., Freytag, V., Schetler, D., Kirchner, L., Schiecke, A., Maar, H., Wicklein, D., Gebauer, F., Bröker, K., Stürken, C., Milde-Langosch, K., Oliveira-Ferrer, L., Ricklefs, F. L., Ewald, F., Wolters-Eisfeld, G., Riecken, K., Unrau, L., Krause, L., Bohnenberger, H., Offermann, A., Perner, S., Sebens, S., Lamszus, K., Diehl, L., Linder, S., Jücker, M., Schumacher, U. & Lange, T., 17.03.2023, In: J HEMATOL ONCOL. 16, 1, 23.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epigenetic Modification of Mesenchymal Stromal Cells Derived from Bone Marrow and Embryonal Tumors to Facilitate Immunotherapeutic Approaches in Pediatric Malignancies
Kruchen, A., Johann, P-D., Rekowski, L. & Müller, I., 03.03.2023, In: CURR ISSUES MOL BIOL. 45, 3, p. 2121-2135 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Outcomes of Childhood Noninfant Acute Lymphoblastic Leukemia With 11q23/KMT2A Rearrangements in a Modern Therapy Era: A Retrospective International Study
Attarbaschi, A., Möricke, A., Harrison, C. J., Mann, G., Baruchel, A., De Moerloose, B., Conter, V., Devidas, M., Elitzur, S., Escherich, G., Hunger, S. P., Horibe, K., Manabe, A., Loh, M. L., Pieters, R., Schmiegelow, K., Silverman, L. B., Stary, J., Vora, A., Pui, C-H., Schrappe, M. & Zimmermann, M., 01.03.2023, In: J CLIN ONCOL. 41, 7, p. 1404-1422 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Surgical Experience Affects the Outcome of Central Venous Access Catheter Implantation in Children: A Retrospective Cohort Study
Fritsch, L-M., Le, M., Elrod, J., Wössmann, W., Vincent, D., Reinshagen, K. & Boettcher, M., 01.03.2023, In: J PEDIAT HEMATOL ONC. 45, 2, p. 57-62 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diagnosis and management of ALK-positive anaplastic large cell lymphoma in children and adolescents
Rigaud, C., Knörr, F., Brugières, L. & Woessmann, W., 03.2023, In: BEST PRACT RES CL HA. 36, 1, p. 101444Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Improving outcomes of childhood and young adult non-Hodgkin lymphoma: 25 years of research and collaboration within the framework of the European Intergroup for Childhood Non-Hodgkin Lymphoma
Beishuizen, A., Mellgren, K., Andrés, M., Auperin, A., Bacon, C. M., Bomken, S., Burke, G. A. A., Burkhardt, B., Brugieres, L., Chiang, A. K. S., Damm-Welk, C., d'Amore, E., Horibe, K., Kabickova, E., Khanam, T., Kontny, U., Klapper, W., Lamant, L., Le Deley, M-C., Loeffen, J., Macintyre, E., Mann, G., Meyer-Wentrup, F., Michgehl, U., Minard-Colin, V., Mussolin, L., Oschlies, I., Patte, C., Pillon, M., Reiter, A., Rigaud, C., Roncery, L., Salaverria, I., Simonitsch-Klupp, I., Uyttebroeck, A., Verdu-Amoros, J., Williams, D., Woessmann, W., Wotherspoon, A., Wrobel, G., Zimmermann, M., Attarbaschi, A., Turner, S. D. & European Intergroup for Childhood Non-Hodgkin Lymphoma, 03.2023, In: LANCET HAEMATOL. 10, 3, p. e213-e224 12 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Single-cell gene regulatory network prediction by explainable AI
Keyl, P., Bischoff, P., Dernbach, G., Bockmayr, M., Fritz, R., Horst, D., Blüthgen, N., Montavon, G., Müller, K-R. & Klauschen, F., 28.02.2023, In: NUCLEIC ACIDS RES. 51, 4, p. e20Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy
Elitzur, S., Vora, A., Burkhardt, B., Inaba, H., Attarbaschi, A., Baruchel, A., Escherich, G., Gibson, B. E., Liu, H-C., Loh, M. L., Moorman, A. V., Möricke, A., Pieters, R., Uyttebroeck, A., Baird, S., Bartram, J., Barzilai-Birenboim, S., Batra, S., Ben-Harosh, M., Bertrand, Y., Buitenkamp, T., Caldwell, K., Drut, R., Geerlinks, A. V., Gilad, G., Grainger, J., Haouy, S., Heaney, N. B., Huang, M., Ingham, D., Krenova, Z., Kuhlen, M., Lehrnbecher, T., Manabe, A., Niggli, F., Paris, C., Revel-Vilk, S., Rohrlich, P., Sinno, M. G., Szczepanski, T., Tamesberger, M., Warrier, R., Wolfl, M., Nirel, R., Izraeli, S., Borkhardt, A. & Schmiegelow, K., 16.02.2023, In: BLOOD. 141, 7, p. 743-755 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DNA methylation subclasses predict the benefit from gross total tumor resection in IDH-wildtype glioblastoma patients
Drexler, R., Schüller, U., Eckhardt, A., Filipski, K., Hartung, T. I., Harter, P. N., Divé, I., Forster, M-T., Czabanka, M., Jelgersma, C., Onken, J., Vajkoczy, P., Capper, D., Siewert, C., Sauvigny, T., Lamszus, K., Westphal, M., Dührsen, L. & Ricklefs, F. L., 14.02.2023, In: NEURO-ONCOLOGY. 25, 2, p. 315-325 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Frequency and prognostic implications of KMT2A rearrangements in children with precursor B-cell lymphoma
Au-Yeung, R. K. H., Padilla, L. A., Zimmermann, M., Reinke, S., Oschlies, I., Escherich, G., Woessmann, W., Burkhardt, B. & Klapper, W., 02.2023, In: LEUKEMIA. 37, 2, p. 488-491 4 p.Research output: SCORING: Contribution to journal › Letter › Research › peer-review
Unveiling the identities of null cell tumours: Epigenomics corroborate subtle histological cues in pituitary neuroendocrine tumour/adenoma classification
Dottermusch, M., Schüller, U., Hagel, C. & Saeger, W., 02.2023, In: NEUROPATH APPL NEURO. 49, 1, p. e12870Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells
Cetin, M. H., Rieckmann, T., Hoffer, K., Riepen, B., Christiansen, S., Gatzemeier, F., Feyerabend, S., Schoof, M., Schüller, U., Petersen, C., Mynarek, M., Rothkamm, K., Kriegs, M. & Struve, N., 29.01.2023, In: RADIAT ONCOL. 18, 1, 19.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Germ Cell Maintenance and Sustained Testosterone and Precursor Hormone Production in Human Prepubertal Testis Organ Culture with Tissues from Boys 7 Years+ under Conditions from Adult Testicular Tissue
Aden, N. L., Bleeke, M., Kordes, U., Brunne, B., Holstermann, B., Biemann, R., Ceglarek, U., Soave, A., Salzbrunn, A., Schneider, S. & Kopylow, K. V., 26.01.2023, In: CELLS-BASEL. 12, 3, 415.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level
Voß, H., Godbole, S., Schlumbohm, S., Schumann, Y., Peng, B., Mynarek, M., Rutkowski, S. J., Dottermusch, M., Dorostkar, M. M., Koshunov, A., Mair, T., Pfister, S. M., Neumann, P., Hartmann, C., Weis, J., Liesche-Starnecker, F., Guan, Y., Schlüter, H., Schüller, U., Krisp, C. & Neumann, J., 09.01.2023, In: bioRxiv. 2023Research output: SCORING: Contribution to journal › Preprint › Research
Allogeneic haematopoietic cell transplant in patients with relapsed/refractory anaplastic large cell lymphoma - Response
Knörr, F. & Woessmann, W., 01.2023, In: BRIT J HAEMATOL. 200, 1, p. 107-108 2 p.Research output: SCORING: Contribution to journal › Letter › Research › peer-review
Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification
Keck, M-K., Sill, M., Wittmann, A., Joshi, P., Stichel, D., Beck, P., Okonechnikow, K., Sievers, P., Wefers, A. K., Roncaroli, F., Avula, S., McCabe, M. G., Hayden, J. T., Wesseling, P., Øra, I., Nistér, M., Kranendonk, M. E. G., Tops, B. B. J., Zapotocky, M., Zamecnik, J., Vasiljevic, A., Fenouil, T., Meyronet, D., von Hoff, K., Schüller, U., Loiseau, H., Figarella-Branger, D., Kramm, C. M., Sturm, D., Scheie, D., Rauramaa, T., Pesola, J., Gojo, J., Haberler, C., Brandner, S., Jacques, T., Sexton Oates, A., Saffery, R., Koscielniak, E., Baker, S. J., Yip, S., Snuderl, M., Ud Din, N., Samuel, D., Schramm, K., Blattner-Johnson, M., Selt, F., Ecker, J., Milde, T., von Deimling, A., Korshunov, A., Perry, A., Pfister, S. M., Sahm, F., Solomon, D. A. & Jones, D. T. W., 01.2023, In: ACTA NEUROPATHOL. 145, 1, p. 49-69 21 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts
Mynarek, M., Obrecht, D., Sill, M., Sturm, D., Kloth-Stachnau, K., Selt, F., Ecker, J., von Hoff, K., Juhnke, B-O., Goschzik, T., Pietsch, T., Bockmayr, M., Kool, M., von Deimling, A., Witt, O., Schüller, U., Benesch, M., Gerber, N. U., Sahm, F., Jones, D. T. W., Korshunov, A., Pfister, S. M., Rutkowski, S. & Milde, T., 01.2023, In: ACTA NEUROPATHOL. 145, 1, p. 97-112 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Left ventricular diastolic filling patterns in competitive triathletes with and without myocardial fibrosis by cardiac magnetic resonance time-volume analysis
Chen, H., Jungesblut, J., Saering, D., Muellerleile, K., Beitzen-Heineke, A., Harms, P., Erley, J., Schoennagel, B., Schneider, J. N., Cavus, E., Fischer, R., Lund, G. K., Adam, G. & Tahir, E., 01.2023, In: EUR J RADIOL. 158, 110615.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-Term Antibody Response to SARS-CoV-2 in Children
Dunay, G. A., Barroso, M., Woidy, M., Danecka, M. K., Engels, G., Hermann, K., Neumann, F. S., Paul, K., Beime, J., Escherich, G., Fehse, K., Grinstein, L., Haniel, F., Haupt, L. J., Hecher, L., Kehl, T., Kemen, C., Kemper, M. J., Kobbe, R., Kohl, A., Klokow, T., Nörz, D., Olfe, J., Schlenker, F., Schmiesing, J., Schrum, J., Sibbertsen, F., Stock, P., Tiede, S., Vettorazzi, E., Zazara, D. E., Zapf, A., Lütgehetmann, M., Oh, J., Mir, T. S., Muntau, A. C., Gersting, S. W. & C19.CHILD Study Group, 01.2023, In: J CLIN IMMUNOL. 43, 1, p. 46-56 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A multi-institutional retrospective pooled outcome analysis of molecularly annotated pediatric supratentorial ZFTA-fused ependymoma
Ng, C. H., Obrecht, D., Wells, O., Zapotocky, M., Sumerauer, D., Coltin, H., Khuong-Quang, D-A., Eisenstat, D. D., Kinross, K. M., White, C. L., Algar, E. M., Luck, A., Witt, H., Schüller, U., Mynarek, M., Pietsch, T., Gerber, N. U., Benesch, M., Warmuth-Metz, M., Kortmann, R., Bison, B., Taylor, M. D., Rutkowski, S., Pfister, S. M., Jones, D. T., Gottardo, N. G., von Hoff, K., Pajtler, K. W., Ramaswamy, V. & Hansford, J. R., 2023, In: NEURO-ONCOL ADV. 5, 1, p. vdad057Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effects of a Pretend Play Intervention on Health-Related Quality of Life in Children With Cancer: A Swedish-German Study
Witt, S., Quitmann, J., Höglund, A. T., Russ, S., Kaman, A., Escherich, G. & Frygner-Holm, S., 2023, In: J PEDIAT HEMAT ONC N. 40, 3, p. 158-169 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A)
Brauer, N., Maruta, Y., Lisci, M., Strege, K., Oschlies, I., Nakamura, H., Böhm, S., Lehmberg, K., Brandhoff, L., Ehl, S., Parvaneh, N., Klapper, W., Fukuda, M., Griffiths, G. M., Hennies, H. C., Niehues, T. & Ammann, S., 2023, In: FRONT IMMUNOL. 14, p. 1151166Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Integrating copy number data of 64 iAMP21 BCP-ALL patients narrows the common region of amplification to 1.57 Mb
Hormann, F. M., Hoogkamer, A. Q., Boeree, A., Sonneveld, E., Escherich, G., den Boer, M. L. & Boer, J. M., 2023, In: FRONT ONCOL. 13, p. 1128560Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Differential Diagnosis of Hyperferritinemia in Critically Ill Patients
Schuster, F. S., Nyvlt, P., Heeren, P., Spies, C., Adam, M. F., Schenk, T., Brunkhorst, F. M., Janka, G., La Rosée, P., Lachmann, C. & Lachmann, G., 27.12.2022, In: J CLIN MED. 12, 1, 192.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dormant SOX9-positive cells facilitate MYC-driven recurrence of medulloblastoma
Borgenvik, A., Holmberg, K. O., Bolin, S., Zhao, M., Savov, V., Rosén, G., Hutter, S., Garancher, A., Suryo Rahmanto, A., Bergström, T., Olsen, T. K., Mainwaring, O. J., Sattanino, D., Verbaan, A. D., Rusert, J. M., Sundstrom, A., Ballester Bravo, M., Dang, Y., Wenz, A. S., Richardson, S., Fotaki, G., Hill, R. M., Dubuc, A. M., Kalushkova, A., Remke, M., Cancer, M., Jernberg-Wiklund, H., Giraud, G., Chen, X., Taylor, M. D., Sangfelt, O., Clifford, S. C., Schüller, U., Wechsler-Reya, R. J., Weishaupt, H. & Swartling, F. J., 16.12.2022, In: CANCER RES. 82, 24, p. 4586-4603 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Laparoscopic Subtotal Splenectomy in Children and Adolescents With Spherocytosis
Le, M., Grosse, R., Elrod, J., Klinke, M., Reinshagen, K. & Boettcher, M., 09.12.2022, In: DTSCH ARZTEBL INT. 119, 49, p. 848-849 2 p.Research output: SCORING: Contribution to journal › Letter › Research › peer-review
Immune Ablation and Stem Cell Rescue in Two Pediatric Patients with Progressive Severe Chronic Graft-Versus-Host Disease
Kloehn, J., Kruchen, A., Schütze, K., Wustrau, K., Schrum, J. & Müller, I., 06.12.2022, In: INT J MOL SCI. 23, 23, 15403.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Amsacrine combined with etoposide and methylprednisolone is a feasible and safe component in first-line intensified treatment of pediatric patients with high-risk acute lymphoblastic leukemia in CoALL08-09 trial
Mezger, K., Ebert, S., Muhle, H. E., Stadt, U. Z., Borkhardt, A., Dilloo, D., Faber, J., Feuchtinger, T., Imschweiler, T., Jorch, N., Pekrun, A., Schmid, I., Schramm, F., Zimmermann, M., Horstmann, M. A. & Escherich, G., 12.2022, In: PEDIATR BLOOD CANCER. 69, 12, e29997.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Essential medicines for childhood cancer in Europe: a pan-European, systematic analysis by SIOPE
Otth, M., Brack, E., Kearns, P. R., Kozhaeva, O., Ocokoljic, M., Schoot, R. A., Vassal, G. & Essential Medicines Group, 12.2022, In: LANCET ONCOL. 23, 12, p. 1537-1546 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas
Goschzik, T., Mynarek, M., Doerner, E., Schenk, A., Spier, I., Warmuth-Metz, M., Bison, B., Obrecht, D., Struve, N., Kortmann, R-D., Schmid, M., Aretz, S., Rutkowski, S. & Pietsch, T., 12.2022, In: ACTA NEUROPATHOL. 144, 6, p. 1143-1156 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Structure and dynamics of the von Willebrand Factor C6 domain
Chen, P-C., Kutzki, F., Mojzisch, A., Simon, B., Xu, E-R., Aponte-Santamaría, C., Horny, K., Jeffries, C., Schneppenheim, R., Wilmanns, M., Brehm, M. A., Gräter, F. & Hennig, J., 12.2022, In: J STRUCT BIOL. 214, 4, 107923.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DNA methylation-based classification of sinonasal tumors
Jurmeister, P., Glöß, S., Roller, R., Leitheiser, M., Schmid, S., Mochmann, L. H., Payá Capilla, E., Fritz, R., Dittmayer, C., Friedrich, C., Thieme, A., Keyl, P., Jarosch, A., Schallenberg, S., Bläker, H., Hoffmann, I., Vollbrecht, C., Lehmann, A., Hummel, M., Heim, D., Haji, M., Harter, P., Englert, B., Frank, S., Hench, J., Paulus, W., Hasselblatt, M., Hartmann, W., Dohmen, H., Keber, U., Jank, P., Denkert, C., Stadelmann, C., Bremmer, F., Richter, A., Wefers, A., Ribbat-Idel, J., Perner, S., Idel, C., Chiariotti, L., Della Monica, R., Marinelli, A., Schüller, U., Bockmayr, M., Liu, J., Lund, V. J., Forster, M., Lechner, M., Lorenzo-Guerra, S. L., Hermsen, M., Johann, P. D., Agaimy, A., Seegerer, P., Koch, A., Heppner, F., Pfister, S. M., Jones, D. T. W., Sill, M., von Deimling, A., Snuderl, M., Müller, K-R., Forgó, E., Howitt, B. E., Mertins, P., Klauschen, F. & Capper, D., 28.11.2022, In: NAT COMMUN. 13, 1, 7148.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Proton Beam Therapy for Pediatric Tumors of the Central Nervous System-Experiences of Clinical Outcome and Feasibility from the KiProReg Study
Peters, S., Frisch, S., Stock, A., Merta, J., Bäumer, C., Blase, C., Schuermann, E., Tippelt, S., Bison, B., Frühwald, M., Rutkowski, S., Fleischhack, G. & Timmermann, B., 28.11.2022, In: CANCERS. 14, 23, 5863.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DNA Methylation subclass Receptor Tyrosine Kinase II (RTK II) is predictive for seizure development in glioblastoma patients
Ricklefs, F. L., Drexler, R., Wollmann, K., Eckhardt, A., Heiland, D. H., Sauvigny, T., Maire, C., Lamszus, K., Westphal, M., Schüller, U. & Dührsen, L., 02.11.2022, In: NEURO-ONCOLOGY. 24, 11, p. 1886-1897 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Aktualisierte AWMF Leitlinie über die Diagnostik und Therapie der akuten lymphoblastische Leukämie im Kindesalter
Escherich, G. & Schrappe, M., 11.2022, In: KLIN PADIATR. 234, 6, p. 363-367 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Coping with Diffuse Intrinsic Pontine Glioma in Children - Findings from an Interview Study on Bereaved Parents
Radlanski, K., Hartwig, M. & Kordes, U., 11.2022, In: KLIN PADIATR. 234, 6, p. 374-381 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic and epigenetic profiling identifies two distinct classes of spinal meningiomas
Ricklefs, F. L., Fita, K., Mohme, M., Mawrin, C., Rahmanzade, R., Sahm, F., Dührsen, L., Göbel, C., Lamszus, K., Westphal, M., Schüller, U. & Eicker, S-O., 11.2022, In: ACTA NEUROPATHOL. 144, 5, p. 1057-1059 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Incidence of subsequent malignancies after total body irradiation-based allogeneic HSCT in children with ALL - long-term follow-up from the prospective ALL-SCT 2003 trial
Eichinger, A., Poetschger, U., Glogova, E., Bader, P., Basu, O., Beier, R., Burkhardt, B., Classen, C-F., Claviez, A., Corbacioglu, S., Deubzer, H. E., Greil, J., Gruhn, B., Güngör, T., Kafa, K., Kühl, J-S., Lang, P., Lange, B. S., Meisel, R., Müller, I., Sauer, M. G., Schlegel, P-G., Schulz, A., Stachel, D., Strahm, B., Wawer, A., Peters, C. & Albert, M. H., 11.2022, In: LEUKEMIA. 36, 11, p. 2567-2576 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Thirteen-month-old girl with hyporegenerative macrocytic anemia due to Brown-Vialetto-Van Laere syndrome 2
Naami, N., Borkhardt, A., Yoshimi, A., Grinstein, L. & Escherich, G., 11.2022, In: AM J HEMATOL. 97, 11, p. 1495-1496 2 p.Research output: SCORING: Contribution to journal › Editorial › Research
Comprehensive profiling of myxopapillary ependymomas identifies a distinct molecular subtype with relapsing disease
Bockmayr, M., Harnisch, K., Pohl, L. C., Schweizer, L., Mohme, T., Körner, M., Alawi, M., Suwala, A. K., Dorostkar, M. M., Monoranu, C. M., Hasselblatt, M., Wefers, A. K., Capper, D., Hench, J., Frank, S., Richardson, T. E., Tran, I., Liu, E., Snuderl, M., Engertsberger, L., Benesch, M., von Deimling, A., Obrecht, D., Mynarek, M., Rutkowski, S., Glatzel, M., Neumann, J. E. & Schüller, U., 03.10.2022, In: NEURO-ONCOLOGY. 24, 10, p. 1689-1699 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MR Imaging and Clinical Characteristics of Diffuse Glioneuronal Tumor with Oligodendroglioma-like Features and Nuclear Clusters
Benesch, M., Perwein, T., Apfaltrer, G., Langer, T., Neumann, A., Brecht, I. B., Schuhmann, M. U., Cario, H., Frühwald, M. C., Vollert, K., van Buiren, M., Deng, M. Y., Seitz, A., Haberler, C., Mynarek, M., Kramm, C., Sahm, F., Robe, P. A., Dankbaar, J. W., Hoff, K. V., Warmuth-Metz, M. & Bison, B., 10.2022, In: AM J NEURORADIOL. 43, 10, p. 1523-1529 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteonekrosen – gravierende Therapiefolge bei akuter lymphoblastischer Leukämie
Kuhlen, M., Kunstreich, M., Gökbuget, N. & Escherich, G., 10.2022, In: ORTHOPADIE. 51, 10, p. 792-799 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
A conformational transition of the D'D3 domain primes von Willebrand factor for multimerization
Gruber, S., Löf, A., Hausch, A., Kutzki, F., Jöhr, R., Obser, T., König, G., Schneppenheim, R., Aponte-Santamaría, C., Gräter, F., Brehm, M. A., Benoit, M. & Lipfert, J., 13.09.2022, In: BLOOD ADV. 6, 17, p. 5198-5209 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SMARCB1-deficient and SMARCA4-deficient Malignant Brain Tumors With Complex Copy Number Alterations and TP53 Mutations May Represent the First Clinical Manifestation of Li-Fraumeni Syndrome
Hasselblatt, M., Thomas, C., Federico, A., Nemes, K., Johann, P. D., Bison, B., Bens, S., Dahlum, S., Kordes, U., Redlich, A., Lessel, L., Pajtler, K. W., Mawrin, C., Schüller, U., Nolte, K., Kramm, C. M., Hinz, F., Sahm, F., Giannini, C., Penkert, J., Kratz, C. P., Pfister, S. M., Siebert, R., Paulus, W., Kool, M. & Frühwald, M. C., 01.09.2022, In: AM J SURG PATHOL. 46, 9, p. 1277-1283 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Artificial intelligence and pathology: From principles to practice and future applications in histomorphology and molecular profiling
Stenzinger, A., Alber, M., Allgäuer, M., Jurmeister, P., Bockmayr, M., Budczies, J., Lennerz, J., Eschrich, J., Kazdal, D., Schirmacher, P., Wagner, A. H., Tacke, F., Capper, D., Müller, K-R. & Klauschen, F., 09.2022, In: SEMIN CANCER BIOL. 84, p. 129-143 15 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Characterization of IG-MYC-breakpoints and their application for quantitative minimal disease monitoring in high-risk pediatric Burkitt-lymphoma and -leukemia
Möker, P., Zur Stadt, U., Zimmermann, M., Alawi, M., Mueller, S., Finger, J., Knörr, F., Riquelme, A., Oschlies, I., Klapper, W., Bradtke, J., Burkhardt, B., Woessmann, W. & Damm-Welk, C., 09.2022, In: LEUKEMIA. 36, 9, p. 2343-2346 4 p.Research output: SCORING: Contribution to journal › Letter › Research
Global effort to evacuate Ukrainian children with cancer and blood disorders who have been affected by war
Agulnik, A., Kizyma, R., Salek, M., Wlodarski, M. W., Pogorelyy, M., Oszer, A., Yakimkova, T., Nogovitsyna, Y., Dutkiewicz, M., Dalle, J-H., Dirksen, U., Eggert, A., Fernández-Teijeiro, A., Greiner, J., Kraal, K., Mueller, A., Sramkova, L., Zecca, M., Wise, P. H., Mlynarski, W. & SAFER Ukraine Collaborative, 09.2022, In: LANCET HAEMATOL. 9, 9, p. e645-e647Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma
Garces de Los Fayos Alonso, I., Zujo, L., Wiest, I., Kodajova, P., Timelthaler, G., Edtmayer, S., Zrimšek, M., Kollmann, S., Giordano, C., Kothmayer, M., Neubauer, H. A., Dey, S., Schlederer, M., Schmalzbauer, B. S., Limberger, T., Probst, C., Pusch, O., Högler, S., Tangermann, S., Merkel, O., Schiefer, A. I., Kornauth, C., Prutsch, N., Zimmerman, M., Abraham, B., Anagnostopoulos, J., Quintanilla-Martinez, L., Mathas, S., Wolf, P., Stoiber, D., Staber, P. B., Egger, G., Klapper, W., Woessmann, W., Look, T. A., Gunning, P., Turner, S. D., Moriggl, R., Lagger, S. & Kenner, L., 31.08.2022, In: MOL CANCER. 21, 1, p. 172Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genotype-phenotype associations within the Li-Fraumeni spectrum: a report from the German Registry
Penkert, J., Strüwe, F. J., Dutzmann, C. M., Doergeloh, B. B., Montellier, E., Freycon, C., Keymling, M., Schlemmer, H-P., Sänger, B., Hoffmann, B., Gerasimov, T., Blattmann, C., Fetscher, S., Frühwald, M., Hettmer, S., Kordes, U., Ridola, V., Kroiss Benninger, S., Mastronuzzi, A., Schott, S., Nees, J., Prokop, A., Redlich, A., Seidel, M. G., Zimmermann, S., Pajtler, K. W., Pfister, S. M., Hainaut, P. & Kratz, C. P., 16.08.2022, In: J HEMATOL ONCOL. 15, 1, 107.Research output: SCORING: Contribution to journal › Letter › Research
ALK inhibition as a salvage therapy for a relapsed unclassifiable sarcomatous CNS tumor with EML4/ALK fusion in an infant
Holsten, T., Bronsema, A., Sturm, D., Sahm, F., Rutkowski, S., Ulrich, S., Wößmann, W. & Kordes, U. R., 08.2022, In: PEDIATR BLOOD CANCER. 69, 8, e29594.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high-hyperdiploid B-cell acute lymphoblastic leukemia
Ramos-Muntada, M., Trincado, J. L., Blanco, J., Bueno, C., Rodríguez-Cortez, V. C., Bataller, A., López-Millán, B., Schwab, C., Ortega, M., Velasco, P., Blanco, M. L., Nomdedeu, J., Ramírez-Orellana, M., Minguela, A., Fuster, J. L., Cuatrecasas, E., Camós, M., Ballerini, P., Escherich, G., Boer, J., DenBoer, M., Hernández-Rivas, J. M., Calasanz, M. J., Cazzaniga, G., Harrison, C. J., Menéndez, P. & Molina, O., 08.2022, In: MOL ONCOL. 16, 16, p. 2899-2919 21 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disruption of GMNC-MCIDAS multiciliogenesis program is critical in choroid plexus carcinoma development
Li, Q., Han, Z., Singh, N., Terré, B., Fame, R. M., Arif, U., Page, T. D., Zahran, T., Abdeltawab, A., Huang, Y., Cao, P., Wang, J., Lu, H., Lidov, H. G. W., Surendran, K., Wu, L., Virga, J. Q., Zhao, Y-T., Ulrich, S., Wechsler-Reya, R. J., Lehtinen, M. K., Roy, S., Liu, Z., Stracker, T. H. & Zhao, H., 08.2022, In: CELL DEATH DIFFER. 29, 8, p. 1596-1610 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fear of progression in parents of childhood cancer survivors: prevalence and associated factors
Peikert, M. L., Inhestern, L., Krauth, K. A., Escherich, G., Rutkowski, S., Kandels, D., Schiekiera, L. J. & Bergelt, C., 08.2022, In: J CANCER SURVIV. 16, 4, p. 823-833 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene expression profiling of Group 3 medulloblastomas defines a clinically tractable stratification based on KIRREL2 expression
Korshunov, A., Okonechnikov, K., Stichel, D., Schrimpf, D., Delaidelli, A., Tonn, S., Mynarek, M., Sievers, P., Sahm, F., Jones, D. T. W., von Deimling, A., Pfister, S. M. & Kool, M., 08.2022, In: ACTA NEUROPATHOL. 144, 2, p. 339-352 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduced adhesion of aged intestinal stem cells contributes to an accelerated clonal drift
Hageb, A., Thalheim, T., Nattamai, K. J., Möhrle, B., Saçma, M., Sakk, V., Thielecke, L., Kerstin, C., Grandy, C., Port, F., Gottschalk, K-E., Mallm, J-P., Glauche, I., Galle, J., Mulaw, M. A. & Geiger, H., 08.2022, In: LIFE SCI ALLIANCE. 5, 8, e202201408.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Persistence of MERS-CoV-spike-specific B cells and antibodies after late third immunization with the MVA-MERS-S vaccine
Weskamm, L. M., Fathi, A., Raadsen, M. P., Mykytyn, A. Z., Koch, T., Spohn, M., Friedrich, M., MVA-MERS-S Study Group, Haagmans, B. L., Becker, S., Sutter, G., Dahlke, C. & Addo, M. M., 19.07.2022, In: CELL REP MED. 3, 7, 100685.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age
Burkhardt, B., Michgehl, U., Rohde, J., Erdmann, T., Berning, P., Reutter, K., Rohde, M., Borkhardt, A., Burmeister, T., Dave, S., Tzankov, A., Dugas, M., Sandmann, S., Fend, F., Finger, J., Mueller, S., Gökbuget, N., Haferlach, T., Kern, W., Hartmann, W., Klapper, W., Oschlies, I., Richter, J., Kontny, U., Lutz, M., Maecker-Kolhoff, B., Ott, G., Rosenwald, A., Siebert, R., von Stackelberg, A., Strahm, B., Woessmann, W., Zimmermann, M., Zapukhlyak, M., Grau, M. & Lenz, G., 06.07.2022, In: NAT COMMUN. 13, 1, 3881.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evaluation of dose, volume and outcome in children with localized, intracranial ependymoma treated with proton therapy within the prospective KiProReg Study
Peters, S., Merta, J., Schmidt, L., Jazmati, D., Kramer, P. H., Blase, C., Tippelt, S., Fleischhack, G., Stock, A., Bison, B., Rutkowski, S., Pietsch, T., Kortmann, R. D. & Timmermann, B., 01.07.2022, In: NEURO-ONCOLOGY. 24, 7, p. 1193-1202 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pediatric T-ALL type-1 and type-2 relapses develop along distinct pathways of clonal evolution
Richter-Pechańska, P., Kunz, J. B., Rausch, T., Erarslan-Uysal, B., Bornhauser, B., Frismantas, V., Assenov, Y., Zimmermann, M., Happich, M., von Knebel-Doeberitz, C., von Neuhoff, N., Köhler, R., Stanulla, M., Schrappe, M., Cario, G., Escherich, G., Kirschner-Schwabe, R., Eckert, C., Avigad, S., Pfister, S. M., Muckenthaler, M. U., Bourquin, J-P., Korbel, J. O. & Kulozik, A. E., 07.2022, In: LEUKEMIA. 36, 7, p. 1759-1768 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond
Kresbach, C., Neyazi, S. & Schüller, U., 07.2022, In: BRAIN PATHOL. 32, 4, e13068.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma
Ravi, V. M., Will, P., Kueckelhaus, J., Sun, N., Joseph, K., Salié, H., Vollmer, L., Kuliesiute, U., von Ehr, J., Benotmane, J. K., Neidert, N., Follo, M., Scherer, F., Goeldner, J. M., Behringer, S. P., Franco, P., Khiat, M., Zhang, J., Hofmann, U. G., Fung, C., Ricklefs, F. L., Lamszus, K., Boerries, M., Ku, M., Beck, J., Sankowski, R., Schwabenland, M., Prinz, M., Schüller, U., Killmer, S., Bengsch, B., Walch, A. K., Delev, D., Schnell, O. & Heiland, D. H., 13.06.2022, In: CANCER CELL. 40, 6, p. 639-655.e13Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Patient-level proteomic network prediction by explainable artificial intelligence
Keyl, P., Michael, B., Heim, D., Dernbach, G., Montavon, G., Müller, K-R. & Klauschen, F., 07.06.2022, In: NPJ PRECIS ONCOL. 6, 1, 35.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance
Federico, A., Thomas, C., Miskiewicz, K., Woltering, N., Zin, F., Nemes, K., Bison, B., Johann, P. D., Hawes, D., Bens, S., Kordes, U., Albrecht, S., Dohmen, H., Hauser, P., Keyvani, K., van Landeghem, F. K. H., Lund, E. L., Scheie, D., Mawrin, C., Monoranu, C-M., Parm Ulhøi, B., Pietsch, T., Reinhard, H., Riemenschneider, M. J., Sehested, A., Sumerauer, D., Siebert, R., Paulus, W., Frühwald, M. C., Kool, M. & Hasselblatt, M., 06.2022, In: ACTA NEUROPATHOL. 143, 6, p. 697-711 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC
Hasselblatt, M., Thomas, C., Federico, A., Bens, S., Hellström, M., Casar-Borota, O., Kordes, U., Neumann, J. E., Dottermusch, M., Rodriguez, F. J., Lo, A. C., Cheng, S., Hendson, G., Hukin, J., Hartmann, C., Koch, A., Capper, D., Siebert, R., Paulus, W., Nemes, K., Johann, P. D., Frühwald, M. C. & Kool, M., 06.2022, In: NEUROPATH APPL NEURO. 48, 4, p. e12797 e12797.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MODL-03. Establishment of intraventricular Shh inhibition as a therapeutic option for young patients with medulloblastoma
Kresbach, C., Schoof, M., Holst, L., Leven, T., Yorgan, T. A., Wrzeszcz, A., Rutkowski, S. J. & Schüller, U., 06.2022, In: NEURO-ONCOLOGY. 24, S1, p. i168Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
Looking back: Identifying supportive care and unmet needs of parents of children receiving specialist paediatric palliative care from the bereavement perspective
Bronsema, A., Theißen, T., Oechsle, K., Wikert, J., Escherich, G., Rutkowski, S., Bokemeyer, C. & Ullrich, A., 25.05.2022, In: BMC PALLIAT CARE. 21, 1, 87.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long noncoding RNAs as regulators of pediatric acute myeloid leukemia
Neyazi, S., Ng, M., Heckl, D. & Klusmann, J-H., 20.05.2022, In: Molecular and cellular pediatrics. 9, 1, 10.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol
Toksvang, L. N., Als-Nielsen, B., Bacon, C., Bertasiute, R., Duarte, X., Escherich, G., Helgadottir, E. A., Johannsdottir, I. R., Jónsson, Ó. G., Kozlowski, P., Langenskjöld, C., Lepik, K., Niinimäki, R., Overgaard, U. M., Punab, M., Räty, R., Segers, H., van der Sluis, I., Smith, O. P., Strullu, M., Vaitkevičienė, G., Wik, H. S., Heyman, M. & Schmiegelow, K., 02.05.2022, In: BMC CANCER. 22, 1, 483.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acute Lymphoblastic Leukemia Study Group
Escherich, G., Zur Stadt, U., Borkhardt, A., Dilloo, D., Faber, J., Feuchtinger, T., Imschweiler, T., Jorch, N., Pekrun, A., Schmid, I., Schramm, F., Spohn, M., Zimmermann, M. & Horstmann, M. A., 01.05.2022, In: HAEMATOLOGICA. 107, 5, p. 1026-1033 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults
Hines, M. R., von Bahr Greenwood, T., Beutel, G., Beutel, K., Hays, J. A., Horne, A., Janka, G., Jordan, M. B., van Laar, J. A. M., Lachmann, G., Lehmberg, K., Machowicz, R., Miettunen, P., La Rosée, P., Shakoory, B., Zinter, M. S. & Henter, J-I., 01.05.2022, In: CRIT CARE MED. 50, 5, p. 860-872 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Does the Y chromosome play a role for outcome in childhood acute lymphoblastic leukemia?
Conter, V., Schrappe, M. & Escherich, G., 01.05.2022, In: CANCER-AM CANCER SOC. 128, 9, p. 1727-1729 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Allogeneic hematopoietic stem cell transplantation for adult HLH: a retrospective study by the chronic malignancies and inborn errors working parties of EBMT
Machowicz, R., Suarez, F., Wiktor-Jedrzejczak, W., Eikema, D-J., de Wreede, L. C., Blok, H-J., Isaksson, C., Einsele, H., Poiré, X., van Dorp, S., Nikolousis, E., Johansson, J-E., Kobbe, G., Zecca, M., Arnold, R., Gerbitz, A., Finke, J., Díez-Martín, J. L., Bonifazi, F., McQuaker, G., Lenhoff, S., Rohrlich, P-S., Theobald, M., Ljungman, P., Collin, M., Albert, M. H., Ehninger, G., Carlson, K., Halaburda, K., Lehmberg, K., Schönland, S., Yakoub-Agha, I., Gennery, A. R., Lankester, A. C. & Kröger, N., 05.2022, In: BONE MARROW TRANSPL. 57, 5, p. 817-823 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of single copy gene‑based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19‑directed CAR T cells in treated patients
Schubert, M-L., Berger, C., Kunz, A., Schmitt, A., Badbaran, A., Neuber, B., Zeschke, S., Wang, L., Riecken, K., Hückelhoven-Krauss, A., Müller, I., Müller-Tidow, C., Dreger, P., Kröger, N., Ayuk, F. A., Schmitt, M. & Fehse, B., 05.2022, In: INT J ONCOL. 60, 5, 48.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population
Nemes, K., Johann, P. D., Steinbügl, M., Gruhle, M., Bens, S., Kachanov, D., Teleshova, M., Hauser, P., Simon, T., Tippelt, S., Eberl, W., Chada, M., Lopez, V. S-M., Grigull, L., Hernáiz-Driever, P., Eyrich, M., Pears, J., Milde, T., Reinhard, H., Leipold, A., van de Wetering, M., Gil-da-Costa, M. J., Ebetsberger-Dachs, G., Kerl, K., Lemmer, A., Boztug, H., Furtwängler, R., Kordes, U., Vokuhl, C., Hasselblatt, M., Bison, B., Kröncke, T., Melchior, P., Timmermann, B., Gerss, J., Siebert, R. & Frühwald, M. C., 27.04.2022, In: CANCERS. 14, 9, 2185.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Children with cancer and their families after active treatment: analyses of biopsychosocial needs and implications for healthcare - a study protocol
Inhestern, L., Paul, V., Winzig, J., Rutkowski, S., Escherich, G. & Bergelt, C., 05.04.2022, In: BMJ OPEN. 12, 4, p. e055633Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Can Machine Learning Models Predict Asparaginase-associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia
Nielsen, R. L., Wolthers, B. O., Helenius, M., Albertsen, B. K., Clemmensen, L., Nielsen, K., Kanerva, J., Niinimäki, R., Frandsen, T. L., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Aytan-Aktug, D., Liu, H-C., Möricke, A., Samarasinghe, S., van der Sluis, I. M., Stanulla, M., Tulstrup, M., Yadav, R., Zapotocka, E., Schmiegelow, K. & Gupta, R., 01.04.2022, In: J PEDIAT HEMATOL ONC. 44, 3, p. e628-e636Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hematopoietic Stem Cell Transplantation with Mesenchymal Stromal Cells in Children with Metachromatic Leukodystrophy
Cabanillas Stanchi, K. M., Böhringer, J., Strölin, M., Groeschel, S., Lenglinger, K., Treuner, C., Kehrer, C., Laugwitz, L., Bevot, A., Kaiser, N., Schumm, M., Lang, P., Handgretinger, R., Krägeloh-Mann, I., Müller, I. & Döring, M., 04.2022, In: STEM CELLS DEV. 31, 7-8, p. 163-175 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Machine Learning Models Predict the Primary Sites of Head and Neck Squamous Cell Carcinoma Metastases Based on DNA Methylation
Leitheiser, M., Capper, D., Seegerer, P., Lehmann, A., Schüller, U., Müller, K-R., Klauschen, F., Jurmeister, P. & Michael, B., 04.2022, In: J PATHOL. 256, 4, p. 378-387 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mucha-Habermann disease: a pediatric case report and proposal of a risk score
Blohm, M. E., Ebenebe, C. U., Rau, C., Escherich, C., Johannsen, J., Escherich, G., Driemeyer, J., Nagel, P. D., Kobbe, R., Lütgehetmann, M., Lennartz, M., Booken, N., Schneider, S. W. & Singer, D., 04.2022, In: INT J DERMATOL. 61, 4, p. 401-409 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Spatial molecular profiling of a central nervous system low-grade diffusely infiltrative tumour with INI1 deficiency featuring a high-grade atypical teratoid/rhabdoid tumour component
Dottermusch, M., Schumann, Y., Kordes, U., Hasselblatt, M. & Neumann, J. E., 04.2022, In: NEUROPATH APPL NEURO. 48, 3, p. e12777 e12777.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantification of Minimal Disease by Digital PCR in ALK-Positive Anaplastic Large Cell Lymphoma: A Step towards Risk Stratification in International Trials?
Damm-Welk, C., Lovisa, F., Contarini, G., Lüdersen, J., Carraro, E., Knörr, F., Förster, J., Zimmermann, M., Sala, A., Vinti, L., Tondo, A., Pillon, M., Woessmann, W. & Mussolin, L., 27.03.2022, In: CANCERS. 14, 7, 1703.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Remission, treatment failure, and relapse in pediatric ALL: An international consensus of the Ponte-di-Legno Consortium
Buchmann, S., Schrappe, M., Baruchel, A., Biondi, A., Borowitz, M. J., Campbell, M., Cario, G., Cazzaniga, G., Escherich, G., Harrison, C. J., Heyman, M., Hunger, S. P., Kiss, C., Liu, H-C., Locatelli, F., Loh, M. L., Manabe, A., Mann, G., Pieters, R., Pui, C-H., Rives, S., Schmiegelow, K., Silverman, L. B., Stary, J., Vora, A., Brown, P. A. & Ponte-di-Legno Consortium, 24.03.2022, In: BLOOD. 139, 12, p. 1785-1793 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors
Graf, M., Interlandi, M., Moreno, N., Holdhof, D., Göbel, C., Melcher, V., Mertins, J., Albert, T. K., Kastrati, D., Alfert, A., Holsten, T., de Faria, F., Meisterernst, M., Rossig, C., Warmuth-Metz, M., Nowak, J., Meyer Zu Hörste, G., Mayère, C., Nef, S., Johann, P., Frühwald, M. C., Dugas, M., Schüller, U. & Kerl, K., 22.03.2022, In: NAT COMMUN. 13, 1, 1544.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Reconstitution Dynamics of Cultivated Hematopoietic Stem Cells and Progenitors Is Independent of Age
Gotzhein, F., Aranyossy, T., Thielecke, L., Sonntag, T., Thaden, V., Fehse, B., Müller, I., Glauche, I. & Cornils, K., 15.03.2022, In: INT J MOL SCI. 23, 6, 3160.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased replication stress and R-loop accumulation in EGFRvIII expressing glioblastoma present new therapeutic opportunities
Struve, N., Hoffer, K., Weik, A-S., Riepen, B., Krug, L., Cetin, M. H., Burmester, J., Ott, L., Liebing, J., Gatzemeier, F., Müller-Goebel, J., Bußmann, L., Parplys, A. C., Unger, K., Mansour, W. Y., Schüller, U., Rieckmann, T., Petersen, C., Rothkamm, K., Short, S. C. & Kriegs, M., 12.03.2022, In: NEURO-ONCOL ADV. 4, 1, p. vdab180 vdab180.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influence of Fetomaternal Microchimerism on Maternal NK Cell Reactivity against the Child's Leukemic Blasts
Martin, L-M., Kruchen, A., Fehse, B. & Müller, I., 04.03.2022, In: BIOMEDICINES. 10, 3, 603.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A new amplicon-based gene panel for next generation sequencing characterization of meningiomas
Mawrin, C., Koch, R., Waldt, N., Sandalcioglu, I. E., Braunsdorf, W. K., Warnke, J-P., Goehre, F., Meisel, H-J., Ewald, C., Neyazi, S., Schüller, U. & Kirches, E., 03.2022, In: BRAIN PATHOL. 32, 2, e13046.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Clinical and molecular characterization of isolated M1 disease in pediatric medulloblastoma: experience from the German HIT-MED studies
Obrecht, D., Mynarek, M., Hagel, C., Kwiecien, R., Spohn, M., Bockmayr, M., Bison, B., Pfister, S. M., Jones, D. T. W., Sturm, D., von Deimling, A., Sahm, F., von Hoff, K., Juhnke, B-O., Benesch, M., Gerber, N. U., Friedrich, C., von Bueren, A. O., Kortmann, R-D., Schwarz, R., Pietsch, T., Fleischhack, G., Schüller, U. & Rutkowski, S., 03.2022, In: J NEURO-ONCOL. 157, 1, p. 37-48 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma
Hohm, A., Karremann, M., Gielen, G. H., Pietsch, T., Warmuth-Metz, M., Vandergrift, L. A., Bison, B., Stock, A., Hoffmann, M., Pham, M., Kramm, C. M. & Nowak, J., 03.2022, In: CLIN NEURORADIOL. 32, 1, p. 249-258 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Refining M1 stage in medulloblastoma: criteria for cerebrospinal fluid cytology and implications for improved risk stratification from the HIT-2000 trial
Hagel, C., Sloman, V., Mynarek, M., Petrasch, K., Obrecht, D., Kühl, J., Deinlein, F., Schmid, R., von Bueren, A. O., Friedrich, C., Juhnke, B. O., Gerber, N. U., Kwiecien, R., Girschick, H., Höller, A., Zapf, A., von Hoff, K. & Rutkowski, S., 03.2022, In: EUR J CANCER. 164, p. 30-38Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review