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Department of Biochemistry and Molecular Cell Biology

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  1. Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine

    Niemann, B., Haufs-Brusberg, S., Puetz, L., feickert, M., Jaeckstein, M. Y., Hoffmann, A., Zurkovic, J., Heine, M., Trautmann, E-M., Müller, CE., Tönies, A., Schlein, C., Jafari, A., Eltzsching, H. K., Gnad, T., Blüher, M., Krahmer, N., Kovacs, P., Heeren, J. & Pfeifer, A., 08.09.2022, In: NATURE. 609, 7926, p. 361–368 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  2. Are different medical school admission tests associated with the outcomes of a simulation-based OSCE?

    Bußenius, L. & Harendza, S., 07.05.2021, In: BMC MED EDUC. 21, 1, p. 263

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Are Exam Questions Known in Advance? Using Local Dependence to Detect Cheating

    Zimmermann, S., Klusmann, D. & Hampe, W., 2016, In: PLOS ONE. 11, 12, p. e0167545

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Arginine and NASH--do macrophages deliver the first hit?

    Scheja, L. & Kluwe, J., 01.02.2015, In: J HEPATOL. 62, 2, p. 260-1 2 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  5. Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice

    Schuran, F. A., Lommetz, C., Steudter, A., Ghallab, A., Wieschendorf, B., Schwinge, D., Zuehlke, S., Reinders, J., Heeren, J., Lohse, A. W., Schramm, C., Herkel, J. & Carambia, A., 2021, In: CELL MOL GASTROENTER. 11, 2, p. 371-388 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. A simple and widely applicable method to 59Fe-radiolabel monodisperse superparamagnetic iron oxide nanoparticles for in vivo quantification studies.

    Freund, B., Tromsdorf, U. I., Bruns, O. T., Heine, M., Giemsa, A., Bartelt, A., Salmen, S. C., Raabe, N., Heeren, J., Ittrich, H., Reimer, R., Hohenberg, H., Schumacher, U., Weller, H. & Nielsen, P., 2012, In: ACS NANO. 6, 8, p. 7318-7325 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Assessing distinguishable social skills in medical admission: does construct-driven development solve validity issues of situational judgment tests?

    Mielke, I., Breil, S. M., Amelung, D., Espe, L. & Knorr, M., 20.04.2022, In: BMC MED EDUC. 22, 1, p. 293

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Assessing language indicators across the lifespan within the German National Educational Panel Study (NEPS)

    Berendes, K., Weinert, S., Zimmermann, S. & Artelt, C., 2013, In: J EDUC RES ONLINE-JE. 5, 2, p. 15-49

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Assessment of iron stores in children with transfusion siderosis by biomagnetic liver susceptometry.

    Fischer, R., Tiemann, C. D., Engelhardt, R., Nielsen, P., Dürken, M., Gabbe, E. E. & Janka-Schaub, G., 1999, In: AM J HEMATOL. 60, 4, p. 289-299 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Assessment of Uptake and Biodistribution of Radiolabeled Cholesterol in Mice Using Gavaged Recombinant Triglyceride-rich Lipoprotein Particles (rTRL)

    Worthmann, A., John, C. & Heeren, J., 05.07.2018, In: BIO-PROTOCOL. 8, 13, p. e2916

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Associations between communication OSCE performance and admission interviews in medical education

    Groene, O., Mielke, I., Knorr, M., Ehrhardt, M. & Bergelt, C., 2022, In: PATIENT EDUC COUNS. 105, 7, p. 2270 - 2275

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. A structural overview of the ion channels of the TRPM family

    Huang, Y., Fliegert, R., Guse, A. H., Lü, W. & Du, J., 01.2020, In: CELL CALCIUM. 85, 102111.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  13. Attenuated viral hepatitis in Trem1-/- mice is associated with reduced inflammatory activity of neutrophils

    Kozik, J-H., Trautmann, T., Carambia, A., Preti, M., Lütgehetmann, M., Krech, T., Wiegard, C., Heeren, J. & Herkel, J., 2016, In: SCI REP-UK. 6, p. 28556

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Attitude and communication skills of German medical students

    Groene, O., Ehrhardt, M. & Bergelt, C., 10.01.2022, In: BMC RES NOTES. 15, 1, p. 11 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Attitudes of patients with schizophrenia and depression to psychiatric research: a study in seven European countries.

    Schäfer, I., Burns, T., Fleischhacker, W. W., Galderisi, S., Rybakowski, J. K., Libiger, J., Rössler, W., Molodynski, A., Edlinger, M., Piegari, G., Jela, H. I., Gorna, K., Jaeger, M., Fett, A-K., Hissbach, J. & Naber, D., 2011, In: SOC PSYCH PSYCH EPID. 46, 2, p. 159-165 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Audio podcasts in practical courses in biochemistry - cost-efficient e-learning in a well-proven format from radio broadcasting

    Münch-Harrach, D., Kothe, C. & Hampe, W., 01.01.2013, In: GMS Z Med Ausbild. 30, 4, p. Doc44

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Author Correction: Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice

    de Jong, J. M. A., Sun, W., Pires, N. D., Frontini, A., Balaz, M., Jespersen, N. Z., Feizi, A., Petrovic, K., Fischer, A. W., Bokhari, M. H., Niemi, T., Nuutila, P., Cinti, S., Nielsen, S., Scheele, C., Virtanen, K., Cannon, B., Nedergaard, J., Wolfrum, C. & Petrovic, N., 09.2019, In: NAT METAB. 1, 9, p. 927

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research

  18. Basic Principles of Science in Medical Education - Development and Implementation of a Two Week Introductory Track

    Vonneilich, N., Dubben, H-H., Kriston, L., Guse, A. H. & von dem Knesebeck, O., 01.05.2016, In: Creat Educ. 7, 6, p. 831-837

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Education › peer-review

  19. Beneficial effects of IKKε-deficiency on body weight and insulin sensitivity are lost in high fat diet-induced obesity in mice.

    Scheja, L., Heese, B. & Seedorf, K., 2011, In: BIOCHEM BIOPH RES CO. 407, 2, p. 288-294 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Berufsverlaufs- und Lebenszufriedenheit von Ärztinnen in fachärztlicher Weiterbildung mit Kindern im Vergleich zu ihren männlichen Kollegen - Eine longitudinale Untersuchung im Rahmen der KarMed-Studie

    Kocalevent, R-D., Pawlik, J., Selch, S., Nehls, S., Meyer, J., Boczor, S., Scherer, M. & Bussche van den, H., 12.02.2021, In: Z EVIDENZ FORTBILD Q. 161, p. 50-56 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Bestimmung des hypophysären Eisengehaltes mittels Multi-Echo-MRT-R2 Messungen

    Berliner, C., Brehmer, M., Fischer, R., Grosse, R., Karul, M., Keller, S., Schönnagel, B., Wang, J., Adam, G. & Yamamura, J., 2015, In: ROFO-FORTSCHR RONTG. 187, S 01, p. WISS105_1

    Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism

    Oehler, N., Volz, T., Bhadra, O. D., Kah, J., Allweiss, L., Giersch, K., Bierwolf, J., Riecken, K., Pollok, J. M., Lohse, A. W., Fehse, B., Petersen, J., Urban, S., Lütgehetmann, M., Heeren, J. & Dandri, M., 08.04.2014, In: HEPATOLOGY.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Bioavailability of bismuth from 205Bi-labelled pharmaceutical oral Bi-preparations in rats.

    Dresow, B., Nielsen, P., Fischer, R., Wendel, J., Gabbe, E. E. & Heinrich, H. C., 1991, In: ARCH TOXICOL. 65, 8, p. 646-650 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Bioavailability of chromium(III)-supplements in rats and humans.

    Laschinsky, N., Kottwitz, K., Freund, B., Dresow, B., Fischer, R. & Nielsen, P., 2012, In: BIOMETALS. 25, 5, p. 1051-1060 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Bioavailability of iron and cyanide from 59Fe- and 14C-labelled hexacyanoferrates(II) in rats.

    Nielsen, P., Dresow, B., Fischer, R. & Heinrich, H. C., 1990, In: Z NATURFORSCH C. 45, 6, p. 681-690 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Bioavailability of iron and cyanide from oral potassium ferric hexacyanoferrate(II) in humans.

    Nielsen, P., Dresow, B., Fischer, R. & Heinrich, H. C., 1990, In: ARCH TOXICOL. 64, 5, p. 420-422 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Bioavailability of iron from oral ferric polymaltose in humans.

    Nielsen, P., Gabbe, E. E., Fischer, R. & Heinrich, H. C., 1994, In: ARZNEIMITTEL-FORSCH. 44, 6, p. 743-748 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Bioavailability of oral iron drugs as judged by a 59Fe-whole-body counting technique in patients with iron deficiency anaemia. Therapeutic efficacy of iron(II)-glycine sulfate.

    Nielsen, P., Kongi, R., Buggisch, P. & Fischer, R., 2005, In: ARZNEIMITTEL-FORSCH. 55, 7, p. 376-381 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Biochemie hoch2: und Molekularbiologie

    Hampe, W., Fluhrer, R., Kouz, K., Unterleitner, C., Averbeck, B., Dankwardt, A., Duszenko, M., Eberharter, A., Harter, C., Höppner, S., Kindler, S., Kreienkamp, H-J., Korber, P., Neumann, S., Nielsen, P., Salat, D., Schling, P. & Wild-Bode, C., 2019, 1 ed.

    Research output: Book/anthology › Other book › peer-review

  30. Biochemie hoch2: und Molekularbiologie 2. Auflage

    Hampe, W., Fluhrer, R., Kouz, K., Averbeck, B., Dankwardt, A., Duszenko, M., Eberharter, A., Harter, C., Höppner, S., Kindler, S., Korber, P., Kreienkamp, H-J., Neumann, S., Nielsen, P., Salat, D., Schling, P., Unterleitner, C. & Wild-Bode, C., 2023, 2 ed.

    Research output: Book/anthology › Other book › peer-review

  31. Biosynthesis of riboflavin. Characterization of the product of the deaminase.

    Nielsen, P. & Bacher, A., 1981, In: BBA-BIOMEMBRANES. 662, 2, p. 312-317 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Biosynthesis of riboflavin. Enzymatic formation of the xylene moiety from [14C]ribulose 5-phosphate.

    Nielsen, P., Neuberger, G., Floss, H. G. & Bacher, A., 1984, In: BIOCHEM BIOPH RES CO. 118, 3, p. 814-820 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Brain insulin controls adipose tissue lipolysis and lipogenesis.

    Scherer, T., O'Hare, J., Diggs-Andrews, K., Schweiger, M., Cheng, B., Lindtner, C., Zielinski, E., Vempati, P., Su, K., Dighe, S., Milsom, T., Puchowicz, M., Scheja, L., Zechner, R., Fisher, S. J., Previs, S. F. & Buettner, C., 2011, In: CELL METAB. 13, 2, p. 183-194 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism

    Shin, A. C., Fasshauer, M., Filatova, N., Grundell, L. A., Zielinski, E., Zhou, J-Y., Scherer, T., Lindtner, C., White, P. J., Lapworth, A. L., Ilkayeva, O., Knippschild, U., Wolf, A. M., Scheja, L., Grove, K. L., Smith, R. D., Qian, W-J., Lynch, C. J., Newgard, C. B. & Buettner, C., 04.11.2014, In: CELL METAB. 20, 5, p. 898-909 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Brown adipose tissue activity controls triglyceride clearance.

    Bartelt, A., Bruns, O. T., Reimer, R., Hohenberg, H., Ittrich, H., Peldschus, K., Kaul, M., Tromsdorf, U. I., Weller, H., Waurisch, C., Eychmüller, A., Gordts, P. L. S. M., Rinninger, F., Brügelmann, K., Freund, B., Nielsen, P., Merkel, M. & Heeren, J., 2011, In: NAT MED. 17, 2, p. 200-205 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. Brown adipose tissue and lipid metabolism

    Heeren, J. & Scheja, L., 06.2018, In: CURR OPIN LIPIDOL. 29, 3, p. 180-185 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  37. Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice

    Fischer, A. W., Behrens, J., Sass, F., Schlein, C., Heine, M., Pertzborn, P., Scheja, L. & Heeren, J., 11.2020, In: J LIPID RES. 61, 11, p. 1377-1389 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

    Berbée, J. F. P., Boon, M. R., Khedoe, P. P. S. J., Bartelt, A., Schlein, C., Worthmann, A., Kooijman, S., Hoeke, G., Mol, I. M., John, C., Jung, C., Vazirpanah, N., Brouwers, L. P. J., Gordts, P. L. S. M., Esko, J. D., Hiemstra, P. S., Havekes, L. M., Scheja, L., Heeren, J. & Rensen, P. C. N., 2015, In: NAT COMMUN. 6, p. 6356

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Burnout is associated with work-family conflict and gratification crisis among German resident physicians

    Kocalevent, R., Pinnschmidt, H., Selch, S., Nehls, S., Meyer, J., Boczor, S., Scherer, M. & van den Bussche, H., 08.05.2020, In: BMC MED EDUC. 20, 1, p. 145

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Ca2+ Microdomains in T-Lymphocytes

    Wolf, I. & Guse, A., 02.05.2017, In: FRONT ONCOL.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  41. Ca(2+) microdomains, NAADP and type 1 ryanodine receptor in cell activation.

    Guse, A. & Wolf, I., 06.2016, In: BBA-MOL CELL RES. 1863, 6, p. 1379-1384

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease

    Marín, T., Dulcey, A. E., Campos, F., de la Fuente, C., Acuña, M., Castro, J., Pinto, C., Yañez, M. J., Cortez, C., McGrath, D. W., Sáez, P. J., Gorshkov, K., Zheng, W., Southall, N., Carmo-Fonseca, M., Marugán, J., Alvarez, A. R. & Zanlungo, S., 2022, In: FRONT CELL DEV BIOL. 10, 844297.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. cADPR Does Not Activate TRPM2

    Riekehr, W. M., Sander, S., Pick, J., Tidow, H., Bauche, A., Guse, A. H. & Fliegert, R., 15.03.2022, In: INT J MOL SCI. 23, 6, 3163.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Calcium channel β3 subunit regulates ATP-dependent migration of dendritic cells

    Woo, M. S., Ufer, F., Sonner, J. K., Belkacemi, A., Tintelnot, J., Sáez, P. J., Krieg, P. F., Mayer, C., Binkle-Ladisch, L., Engler, J. B., Bauer, S., Kursawe, N., Vieira, V., Mannebach, S., Freichel, M., Flockerzi, V., Vargas, P. & Friese, M. A., 22.09.2023, In: SCI ADV. 9, 38, eadh1653.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Calcium mobilizing second messengers derived from NAD

    Guse, A. H., 01.09.2015, In: BBA-PROTEINS PROTEOM. 1854, 9, p. 1132-1137

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation

    Nebel, M., Zhang, B., Odoardi, F., Flügel, A., Potter, B. V. L. & Guse, A. H., 06.2015, In: Messenger (Los Angel). 4, 1, p. 104-111 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice

    Baumeier, C., Kaiser, D., Heeren, J., Scheja, L., John, C., Weise, C., Eravci, M., Lagerpusch, M., Schulze, G., Joost, H-G., Schwenk, R. W. & Schürmann, A., 05.2015, In: Biochim Biophys Acta. 1851, 5, p. 566-76 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation.

    Atanackovic, D., Arfsten, J., Cao, Y., Gnjatic, S., Schnieders, F., Bartels, K., Schilling, G., Faltz, C., Wolschke, C., Dierlamm, J., Ritter, G., Eiermann, T., Hossfeld, D. K., Zander, A. R., Jungbluth, A. A., Old, L. J., Bokemeyer, C. & Kröger, N., 2007, In: BLOOD. 109, 3, p. 1103-1112 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. Can Different Admissions to Medical School Predict Performance of Non-Technical Skill Performance in Simulated Clinical Settings?

    Moll-Khosrawi, P., Hampe, W., Schulte-Uentrop, L., Zöllner, C., Zimmermann, S. & Huelmann, T., 23.12.2022, In: HEALTHCARE-BASEL. 11, 1, 46.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. CD38 downregulation modulates NAD+ and NADP(H) levels in thermogenic adipose tissues

    Benzi, A., Sturla, L., Heine, M., Fischer, A. W., Spinelli, S., Magnone, M., Sociali, G., Parodi, A., Fenoglio, D., Emionite, L., Koch-Nolte, F., Mittrücker, H-W., Guse, A. H., De Flora, A., Zocchi, E., Heeren, J. & Bruzzone, S., 01.2021, In: BBA-MOL CELL BIOL L. 1866, 1, p. 158819

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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