Dr.med. ID: 63283
Marc Lütgehetmann
Publications
- 2015
Association of hepatitis E virus and essential cryoglobulinemia?
Pischke, S., Polywka, S., Haag, F., Iking-Konert, C., Sterneck, M., Lütgehetmann, M., Dammermann, W., Lüth, S. & Schirmer, J. H., 06.2015, In: J CLIN VIROL. 67, p. 23-24 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody
Mailly, L., Xiao, F., Lupberger, J., Wilson, G. K., Aubert, P., Duong, F. H. T., Calabrese, D., Leboeuf, C., Fofana, I., Thumann, C., Bandiera, S., Lütgehetmann, M., Volz, T., Davis, C., Harris, H. J., Mee, C. J., Girardi, E., Chane-Woon-Ming, B., Ericsson, M., Fletcher, N., Bartenschlager, R., Pessaux, P., Vercauteren, K., Meuleman, P., Villa, P., Kaderali, L., Pfeffer, S., Heim, M. H., Neunlist, M., Zeisel, M. B., Dandri-Petersen, M., McKeating, J. A., Robinet, E. & Baumert, T. F., 05.2015, In: NAT BIOTECHNOL. 33, 5, p. 549-54 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Experimental Models: Cell Culture and Animal Models
Dandri-Petersen, M., Volz, T. & Lütgehetmann, M., 2015, Hepatitis B Virus in Human Diseases . Liaw, Y-F. & Zoulim, F. (eds.). 1 ed. Springer International Publishing, p. 35-62 28 p. (Molecular and Translational Medicine).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2014
Relevance of a Full-Length Genomic RNA Standard and a Thermal-Shock Step for Optimal Hepatitis Delta Virus Quantification
Homs, M., Giersch, K., Blasi, M., Lütgehetmann, M., Buti, M., Esteban, R., Dandri, M. & Rodriguez-Frias, F., 01.09.2014, In: J CLIN MICROBIOL. 52, 9, p. 3334-8 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rapid Metagenomic Diagnostics for Suspected Outbreak of Severe Pneumonia
Fischer, N., Rohde, H., Indenbirken, D., Günther, T., Reumann, K., Lütgehetmann, M., Meyer, T., Kluge, S., Aepfelbacher, M., Alawi, M. & Grundhoff, A., 01.06.2014, In: EMERG INFECT DIS. 20, 6, p. 1072-5 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay
Meyer, T., Franke, G., Polywka, S. K. A., Lütgehetmann, M., Gbadamosi, J., Magnus, T. & Aepfelbacher, M., 01.05.2014, In: J CLIN MICROBIOL. 52, 5, p. 1751-3 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism
Oehler, N., Volz, T., Bhadra, O. D., Kah, J., Allweiss, L., Giersch, K., Bierwolf, J., Riecken, K., Pollok, J. M., Lohse, A. W., Fehse, B., Petersen, J., Urban, S., Lütgehetmann, M., Heeren, J. & Dandri, M., 08.04.2014, In: HEPATOLOGY.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mouse models of hepatitis B and delta virus infection
Dandri, M. & Lütgehetmann, M., 12.03.2014, In: J IMMUNOL METHODS. 410, p. 39-49Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration
Allweiss, L., Volz, T., Lütgehetmann, M., Giersch, K., Bornscheuer, T., Lohse, A. W., Petersen, J., Ma, H., Klumpp, K., Fletcher, S. P. & Dandri, M., 01.03.2014, In: J HEPATOL. 60, 3, p. 500-7 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection
Giersch, K., Helbig, M., Volz, T., Allweiss, L., Mancke, L., Lohse, A. W., Polywka, S., Pollok, J. M., Petersen, J., Taylor, J., Dandri, M. & Lütgehetmann, M., 01.03.2014, In: J HEPATOL. 60, 3, p. 538-44 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
New foe treated with old guns - supportive role of steroids in the treatment of acute severe hepatitis E
Sebode, M., Pischke, S., Lütgehetmann, M., Polywka, S., Quaas, A., Lohse, A. W. & Wege, H., 01.01.2014, In: BMC GASTROENTEROL. 14, 191Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: case report
Leypoldt, F., Titulaer, M. J., Aguilar, E., Walther, J., Bönstrup, M., Havemeister, S., Teegen, B., Lütgehetmann, M., Rosenkranz, M., Magnus, T. & Dalmau, J., 29.10.2013, In: NEUROLOGY. 81, 18, p. 1637-9 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus
Volz, T., Allweiss, L., Ben MBarek, M., Warlich, M., Lohse, A. W., Pollok, J-M., Alexandrov, A., Urban, S., Petersen, J., Lütgehetmann, M. & Dandri, M., 01.05.2013, In: J HEPATOL. 58, 5, p. 861-7 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Experimental models and therapeutic approaches for HBV
Dandri, M., Lütgehetmann, M. & Petersen, J., 01.01.2013, In: SEMIN IMMUNOPATHOL. 35, 1, p. 7-21 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Entecavir plus tenofovir combination as rescue therapy in pre-treated chronic hepatitis B patients: an international multicenter cohort study.
Petersen, J., Ratziu, V., Buti, M., Janssen, H. L. A., Brown, A., Lampertico, P., Schollmeyer, J., Zoulim, F., Wedemeyer, H., Sterneck, M., Berg, T., Sarrazin, C., Lütgehetmann, M. & Buggisch, P., 01.03.2012, In: J HEPATOL. 56, 3, p. 520-526 7 p., 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.
Lütgehetmann, M., Mancke, L., Volz, T., Helbig, M., Allweiss, L., Bornscheuer, T., Pollok, J-M., Lohse, A. W., Petersen, J., Urban, S. & Dandri-Petersen, M., 2012, In: HEPATOLOGY. 55, 3, p. 685-694 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.
Bierwolf, J., Lütgehetmann, M., Deichmann, S., Erbes, J., Volz, T., Dandri-Petersen, M., Cohen, S., Nashan, B. & Pollok, J-M., 2012, In: TISSUE ENG PT A. 18, 13-14, p. 1443-1453 13-14.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.
Volz, T., Lütgehetmann, M., Allweiss, L., Warlich, M., Bierwolf, J., Pollok, J-M., Petersen, J., Matthes, E. & Dandri-Petersen, M., 2012, In: ANTIVIR THER. 17, 4, p. 623-631 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Entecavir treatment for chronic hepatitis B: adaptation is not needed for the majority of naïve patients with a partial virological response
Zoutendijk, R., Reijnders, J. G. P., Brown, A., Zoulim, F., Mutimer, D., Deterding, K., Petersen, J., Hofmann, W. P., Buti, M., Santantonio, T., van Bömmel, F., Pradat, P., Oo, Y., Lütgehetmann, M., Berg, T., Hansen, B. E., Wedemeyer, H., Janssen, H. L. A. & VIRGIL Surveillance Study Group, 08.2011, In: HEPATOLOGY. 54, 2, p. 443-51 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Desperately seeking diarrhoea: outbreak of haemolytic uraemic syndrome caused by emerging sorbitol-fermenting shiga toxin-producing Escherichia coli O157:H-, Germany, 2009.
Nielsen, S., Frank, C., Fruth, A., Spode, A., Prager, R., Graff, A., Plenge-Bönig, A., Loos, S., Lütgehetmann, M., Kemper, M. J., Müller-Wiefel, D. E. & Werber, D., 2011, In: ZOONOSES PUBLIC HLTH. 58, 8, p. 567-572 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Forced activation of β-catenin signaling supports the transformation of hTERT-immortalized human fetal hepatocytes.
Wege, H., Heim, D., Lütgehetmann, M., Dierlamm, J., Lohse, A. W. & Brümmendorf, T. H., 2011, In: MOL CANCER RES. 9, 9, p. 1222-1231 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.
Lütgehetmann, M., Bornscheuer, T., Volz, T., Allweiss, L., Bockmann, J-H., Pollok, J-M., Lohse, A. W., Petersen, J. & Dandri-Petersen, M., 2011, In: GASTROENTEROLOGY. 140, 7, p. 1-2, 2074-2083 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary human hepatocytes on biodegradable poly(l-lactic acid) matrices: a promising model for improving transplantation efficiency with tissue engineering.
Török-Pollok, E., Lütgehetmann, M., Bierwolf, J., Melbeck, S., Düllmann, J., Nashan, B., Ma, P. X. & Pollok, J-M., 2011, In: LIVER TRANSPLANT. 17, 2, p. 104-114 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary rat hepatocyte culture on 3D nanofibrous polymer scaffolds for toxicology and pharmaceutical research.
Bierwolf, J., Lütgehetmann, M., Feng, K., Erbes, J., Deichmann, S., Toronyi, E., Stieglitz, C., Nashan, B., Ma, P. X. & Pollok, J-M., 2011, In: BIOTECHNOL BIOENG. 108, 1, p. 141-150 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking facilitates multicolor clonal cell tracking.
Riecken, K., Thomaschewski, M., Warlich, M., Volz, T., Cornils, K., Niebuhr, B., Täger, M., Lütgehetmann, M., Pollok, J-M., Stocking, C., Dandri-Petersen, M., Benten, D. & Fehse, B., 2011, In: NAT MED. 17, 4, p. 504-509 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Wissensstand, Präventionsverhalten und Therapieadhärenz von Patienten mit chronischer Hepatitis B in einem großen tertiären Zentrum in Deutschland
Lutgehetmann, M., Meyer, F., Volz, T., Lohse, A. W., Fischer, C., Dandri, M. & Petersen, J., 01.09.2010, In: Z GASTROENTEROL. 48, 9, p. 1126-32 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice.
Lütgehetmann, M., Volz, T., Köpke, A., Broja, T., Tigges, E., Lohse, A. W., Fuchs, E., Murray, J. M., Petersen, J. & Dandri-Petersen, M., 2010, In: HEPATOLOGY. 52, 1, p. 16-24 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Knowledge about HBV, prevention behaviour and treatment adherence of patients with chronic hepatitis B in a large referral centre in Germany].
Lütgehetmann, M., Meyer, F., Volz, T., Lohse, A. W., Fischer, C., Dandri-Petersen, M. & Petersen, J., 2010, In: Z GASTROENTEROL. 48, 9, p. 1126-1132 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.
Petersen, J., Dandri-Petersen, M., Mier, W., Lütgehetmann, M., Volz, T., von Weizsäcker, F., Haberkorn, U., Fischer, L., Pollok, J-M., Erbes, B., Seitz, S. & Urban, S., 2008, In: NAT BIOTECHNOL. 26, 3, p. 335-341 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sequential combination therapy leads to biochemical and histological improvement despite low ongoing intrahepatic hepatitis B virus replication.
Lütgehetmann, M., Volz, T., Quaas, A., Zankel, M., Fischer, C., Dandri-Petersen, M. & Petersen, J., 2008, In: ANTIVIR THER. 13, 1, p. 57-66 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia.
Dandri-Petersen, M., Murray, J. M., Lütgehetmann, M., Volz, T., Lohse, A. W. & Petersen, J., 2008, In: HEPATOLOGY. 48, 4, p. 1079-1086 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Impaired intrahepatic hepatitis B virus productivity contributes to low viremia in most HBeAg-negative patients.
Volz, T., Lütgehetmann, M., Wachtler, P., Jacob, A., Quaas, A., Murray, J. M., Dandri-Petersen, M. & Petersen, J., 2007, In: GASTROENTEROLOGY. 133, 3, p. 843-852 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2006
Morphological and functional analysis of rat hepatocyte spheroids generated on poly(L-lactic acid) polymer in a pulsatile flow bioreactor.
Török, E., Vogel, C., Lütgehetmann, M., Ma, P. X., Dandri-Petersen, M., Petersen, J., Burda, M. R., Siebert, K., Düllmann, J., Rogiers, X. & Pollok, J-M., 2006, In: TISSUE ENG. 12, 7, p. 1881-1890 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B.
Wursthorn, K., Lütgehetmann, M., Dandri-Petersen, M., Volz, T., Buggisch, P., Zollner, B., Longerich, T., Schirmacher, P., Metzler, F., Zankel, M., Fischer, C., Currie, G., Brosgart, C. & Petersen, J., 2006, In: HEPATOLOGY. 44, 3, p. 675-684 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Small animal model systems for studying hepatitis B virus replication and pathogenesis.
Dandri-Petersen, M., Lütgehetmann, M., Volz, T. & Petersen, J., 2006, In: SEMIN LIVER DIS. 26, 2, p. 181-191 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Temporary HBV resolution in an HIV-coinfected patient during HBV-directed combination therapy followed by relapse of HBV.
Wursthorn, K., Buggisch, P., Lütgehetmann, M., Zollner, B. & Petersen, J., 2006, In: ANTIVIR THER. 11, 5, p. 647-652 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2005
Animal models for the study of HBV replication and its variants.
Dandri-Petersen, M., Volz, T., Lütgehetmann, M. & Petersen, J., 2005, In: J CLIN VIROL. 34, 1, p. 54-62 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The liver stage of Plasmodium berghei inhibits host cell apoptosis.
van de Sand, C., Horstmann, S., Schmidt, A., Sturm, A., Bolte, S., Krueger, A., Lütgehetmann, M., Pollok, J-M., Libert, C. & Heussler, V. T., 2005, In: MOL MICROBIOL. 58, 3, p. 731-742 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review