Dr.med. ID: 63283

Marc Lütgehetmann

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Publications

  1. 2015
  2. Association of hepatitis E virus and essential cryoglobulinemia?

    Pischke, S., Polywka, S., Haag, F., Iking-Konert, C., Sterneck, M., Lütgehetmann, M., Dammermann, W., Lüth, S. & Schirmer, J. H., 06.2015, In: J CLIN VIROL. 67, p. 23-24 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  3. Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody

    Mailly, L., Xiao, F., Lupberger, J., Wilson, G. K., Aubert, P., Duong, F. H. T., Calabrese, D., Leboeuf, C., Fofana, I., Thumann, C., Bandiera, S., Lütgehetmann, M., Volz, T., Davis, C., Harris, H. J., Mee, C. J., Girardi, E., Chane-Woon-Ming, B., Ericsson, M., Fletcher, N., Bartenschlager, R., Pessaux, P., Vercauteren, K., Meuleman, P., Villa, P., Kaderali, L., Pfeffer, S., Heim, M. H., Neunlist, M., Zeisel, M. B., Dandri-Petersen, M., McKeating, J. A., Robinet, E. & Baumert, T. F., 05.2015, In: NAT BIOTECHNOL. 33, 5, p. 549-54 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Experimental Models: Cell Culture and Animal Models

    Dandri-Petersen, M., Volz, T. & Lütgehetmann, M., 2015, Hepatitis B Virus in Human Diseases . Liaw, Y-F. & Zoulim, F. (eds.). 1 ed. Springer International Publishing, p. 35-62 28 p. (Molecular and Translational Medicine).

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  5. 2014
  6. Relevance of a Full-Length Genomic RNA Standard and a Thermal-Shock Step for Optimal Hepatitis Delta Virus Quantification

    Homs, M., Giersch, K., Blasi, M., Lütgehetmann, M., Buti, M., Esteban, R., Dandri, M. & Rodriguez-Frias, F., 01.09.2014, In: J CLIN MICROBIOL. 52, 9, p. 3334-8 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Rapid Metagenomic Diagnostics for Suspected Outbreak of Severe Pneumonia

    Fischer, N., Rohde, H., Indenbirken, D., Günther, T., Reumann, K., Lütgehetmann, M., Meyer, T., Kluge, S., Aepfelbacher, M., Alawi, M. & Grundhoff, A., 01.06.2014, In: EMERG INFECT DIS. 20, 6, p. 1072-5 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  8. Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay

    Meyer, T., Franke, G., Polywka, S. K. A., Lütgehetmann, M., Gbadamosi, J., Magnus, T. & Aepfelbacher, M., 01.05.2014, In: J CLIN MICROBIOL. 52, 5, p. 1751-3 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism

    Oehler, N., Volz, T., Bhadra, O. D., Kah, J., Allweiss, L., Giersch, K., Bierwolf, J., Riecken, K., Pollok, J. M., Lohse, A. W., Fehse, B., Petersen, J., Urban, S., Lütgehetmann, M., Heeren, J. & Dandri, M., 08.04.2014, In: HEPATOLOGY.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Mouse models of hepatitis B and delta virus infection

    Dandri, M. & Lütgehetmann, M., 12.03.2014, In: J IMMUNOL METHODS. 410, p. 39-49

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Immune cell responses are not required to induce substantial hepatitis B virus antigen decline during pegylated interferon-alpha administration

    Allweiss, L., Volz, T., Lütgehetmann, M., Giersch, K., Bornscheuer, T., Lohse, A. W., Petersen, J., Ma, H., Klumpp, K., Fletcher, S. P. & Dandri, M., 01.03.2014, In: J HEPATOL. 60, 3, p. 500-7 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Persistent hepatitis D virus mono-infection in humanized mice is efficiently converted by hepatitis B virus to a productive co-infection

    Giersch, K., Helbig, M., Volz, T., Allweiss, L., Mancke, L., Lohse, A. W., Polywka, S., Pollok, J. M., Petersen, J., Taylor, J., Dandri, M. & Lütgehetmann, M., 01.03.2014, In: J HEPATOL. 60, 3, p. 538-44 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. New foe treated with old guns - supportive role of steroids in the treatment of acute severe hepatitis E

    Sebode, M., Pischke, S., Lütgehetmann, M., Polywka, S., Quaas, A., Lohse, A. W. & Wege, H., 01.01.2014, In: BMC GASTROENTEROL. 14, 191

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. 2013
  15. Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: case report

    Leypoldt, F., Titulaer, M. J., Aguilar, E., Walther, J., Bönstrup, M., Havemeister, S., Teegen, B., Lütgehetmann, M., Rosenkranz, M., Magnus, T. & Dalmau, J., 29.10.2013, In: NEUROLOGY. 81, 18, p. 1637-9 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus

    Volz, T., Allweiss, L., Ben MBarek, M., Warlich, M., Lohse, A. W., Pollok, J-M., Alexandrov, A., Urban, S., Petersen, J., Lütgehetmann, M. & Dandri, M., 01.05.2013, In: J HEPATOL. 58, 5, p. 861-7 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Experimental models and therapeutic approaches for HBV

    Dandri, M., Lütgehetmann, M. & Petersen, J., 01.01.2013, In: SEMIN IMMUNOPATHOL. 35, 1, p. 7-21 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. 2012
  19. Entecavir plus tenofovir combination as rescue therapy in pre-treated chronic hepatitis B patients: an international multicenter cohort study.

    Petersen, J., Ratziu, V., Buti, M., Janssen, H. L. A., Brown, A., Lampertico, P., Schollmeyer, J., Zoulim, F., Wedemeyer, H., Sterneck, M., Berg, T., Sarrazin, C., Lütgehetmann, M. & Buggisch, P., 01.03.2012, In: J HEPATOL. 56, 3, p. 520-526 7 p., 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Humanized chimeric uPA mouse model for the study of hepatitis B and D virus interactions and preclinical drug evaluation.

    Lütgehetmann, M., Mancke, L., Volz, T., Helbig, M., Allweiss, L., Bornscheuer, T., Pollok, J-M., Lohse, A. W., Petersen, J., Urban, S. & Dandri-Petersen, M., 2012, In: HEPATOLOGY. 55, 3, p. 685-694 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.

    Bierwolf, J., Lütgehetmann, M., Deichmann, S., Erbes, J., Volz, T., Dandri-Petersen, M., Cohen, S., Nashan, B. & Pollok, J-M., 2012, In: TISSUE ENG PT A. 18, 13-14, p. 1443-1453 13-14.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice.

    Volz, T., Lütgehetmann, M., Allweiss, L., Warlich, M., Bierwolf, J., Pollok, J-M., Petersen, J., Matthes, E. & Dandri-Petersen, M., 2012, In: ANTIVIR THER. 17, 4, p. 623-631 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. 2011
  24. Entecavir treatment for chronic hepatitis B: adaptation is not needed for the majority of naïve patients with a partial virological response

    Zoutendijk, R., Reijnders, J. G. P., Brown, A., Zoulim, F., Mutimer, D., Deterding, K., Petersen, J., Hofmann, W. P., Buti, M., Santantonio, T., van Bömmel, F., Pradat, P., Oo, Y., Lütgehetmann, M., Berg, T., Hansen, B. E., Wedemeyer, H., Janssen, H. L. A. & VIRGIL Surveillance Study Group, 08.2011, In: HEPATOLOGY. 54, 2, p. 443-51 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Desperately seeking diarrhoea: outbreak of haemolytic uraemic syndrome caused by emerging sorbitol-fermenting shiga toxin-producing Escherichia coli O157:H-, Germany, 2009.

    Nielsen, S., Frank, C., Fruth, A., Spode, A., Prager, R., Graff, A., Plenge-Bönig, A., Loos, S., Lütgehetmann, M., Kemper, M. J., Müller-Wiefel, D. E. & Werber, D., 2011, In: ZOONOSES PUBLIC HLTH. 58, 8, p. 567-572 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Forced activation of β-catenin signaling supports the transformation of hTERT-immortalized human fetal hepatocytes.

    Wege, H., Heim, D., Lütgehetmann, M., Dierlamm, J., Lohse, A. W. & Brümmendorf, T. H., 2011, In: MOL CANCER RES. 9, 9, p. 1222-1231 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.

    Lütgehetmann, M., Bornscheuer, T., Volz, T., Allweiss, L., Bockmann, J-H., Pollok, J-M., Lohse, A. W., Petersen, J. & Dandri-Petersen, M., 2011, In: GASTROENTEROLOGY. 140, 7, p. 1-2, 2074-2083 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Primary human hepatocytes on biodegradable poly(l-lactic acid) matrices: a promising model for improving transplantation efficiency with tissue engineering.

    Török-Pollok, E., Lütgehetmann, M., Bierwolf, J., Melbeck, S., Düllmann, J., Nashan, B., Ma, P. X. & Pollok, J-M., 2011, In: LIVER TRANSPLANT. 17, 2, p. 104-114 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Primary rat hepatocyte culture on 3D nanofibrous polymer scaffolds for toxicology and pharmaceutical research.

    Bierwolf, J., Lütgehetmann, M., Feng, K., Erbes, J., Deichmann, S., Toronyi, E., Stieglitz, C., Nashan, B., Ma, P. X. & Pollok, J-M., 2011, In: BIOTECHNOL BIOENG. 108, 1, p. 141-150 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. RGB marking facilitates multicolor clonal cell tracking.

    Riecken, K., Thomaschewski, M., Warlich, M., Volz, T., Cornils, K., Niebuhr, B., Täger, M., Lütgehetmann, M., Pollok, J-M., Stocking, C., Dandri-Petersen, M., Benten, D. & Fehse, B., 2011, In: NAT MED. 17, 4, p. 504-509 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. 2010
  32. Wissensstand, Präventionsverhalten und Therapieadhärenz von Patienten mit chronischer Hepatitis B in einem großen tertiären Zentrum in Deutschland

    Lutgehetmann, M., Meyer, F., Volz, T., Lohse, A. W., Fischer, C., Dandri, M. & Petersen, J., 01.09.2010, In: Z GASTROENTEROL. 48, 9, p. 1126-32 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. In vivo proliferation of hepadnavirus-infected hepatocytes induces loss of covalently closed circular DNA in mice.

    Lütgehetmann, M., Volz, T., Köpke, A., Broja, T., Tigges, E., Lohse, A. W., Fuchs, E., Murray, J. M., Petersen, J. & Dandri-Petersen, M., 2010, In: HEPATOLOGY. 52, 1, p. 16-24 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. [Knowledge about HBV, prevention behaviour and treatment adherence of patients with chronic hepatitis B in a large referral centre in Germany].

    Lütgehetmann, M., Meyer, F., Volz, T., Lohse, A. W., Fischer, C., Dandri-Petersen, M. & Petersen, J., 2010, In: Z GASTROENTEROL. 48, 9, p. 1126-1132 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. 2008
  36. Prevention of hepatitis B virus infection in vivo by entry inhibitors derived from the large envelope protein.

    Petersen, J., Dandri-Petersen, M., Mier, W., Lütgehetmann, M., Volz, T., von Weizsäcker, F., Haberkorn, U., Fischer, L., Pollok, J-M., Erbes, B., Seitz, S. & Urban, S., 2008, In: NAT BIOTECHNOL. 26, 3, p. 335-341 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Sequential combination therapy leads to biochemical and histological improvement despite low ongoing intrahepatic hepatitis B virus replication.

    Lütgehetmann, M., Volz, T., Quaas, A., Zankel, M., Fischer, C., Dandri-Petersen, M. & Petersen, J., 2008, In: ANTIVIR THER. 13, 1, p. 57-66 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Virion half-life in chronic hepatitis B infection is strongly correlated with levels of viremia.

    Dandri-Petersen, M., Murray, J. M., Lütgehetmann, M., Volz, T., Lohse, A. W. & Petersen, J., 2008, In: HEPATOLOGY. 48, 4, p. 1079-1086 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. 2007
  40. Impaired intrahepatic hepatitis B virus productivity contributes to low viremia in most HBeAg-negative patients.

    Volz, T., Lütgehetmann, M., Wachtler, P., Jacob, A., Quaas, A., Murray, J. M., Dandri-Petersen, M. & Petersen, J., 2007, In: GASTROENTEROLOGY. 133, 3, p. 843-852 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. 2006
  42. Morphological and functional analysis of rat hepatocyte spheroids generated on poly(L-lactic acid) polymer in a pulsatile flow bioreactor.

    Török, E., Vogel, C., Lütgehetmann, M., Ma, P. X., Dandri-Petersen, M., Petersen, J., Burda, M. R., Siebert, K., Düllmann, J., Rogiers, X. & Pollok, J-M., 2006, In: TISSUE ENG. 12, 7, p. 1881-1890 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Peginterferon alpha-2b plus adefovir induce strong cccDNA decline and HBsAg reduction in patients with chronic hepatitis B.

    Wursthorn, K., Lütgehetmann, M., Dandri-Petersen, M., Volz, T., Buggisch, P., Zollner, B., Longerich, T., Schirmacher, P., Metzler, F., Zankel, M., Fischer, C., Currie, G., Brosgart, C. & Petersen, J., 2006, In: HEPATOLOGY. 44, 3, p. 675-684 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Small animal model systems for studying hepatitis B virus replication and pathogenesis.

    Dandri-Petersen, M., Lütgehetmann, M., Volz, T. & Petersen, J., 2006, In: SEMIN LIVER DIS. 26, 2, p. 181-191 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Temporary HBV resolution in an HIV-coinfected patient during HBV-directed combination therapy followed by relapse of HBV.

    Wursthorn, K., Buggisch, P., Lütgehetmann, M., Zollner, B. & Petersen, J., 2006, In: ANTIVIR THER. 11, 5, p. 647-652 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. 2005
  47. Animal models for the study of HBV replication and its variants.

    Dandri-Petersen, M., Volz, T., Lütgehetmann, M. & Petersen, J., 2005, In: J CLIN VIROL. 34, 1, p. 54-62 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. The liver stage of Plasmodium berghei inhibits host cell apoptosis.

    van de Sand, C., Horstmann, S., Schmidt, A., Sturm, A., Bolte, S., Krueger, A., Lütgehetmann, M., Pollok, J-M., Libert, C. & Heussler, V. T., 2005, In: MOL MICROBIOL. 58, 3, p. 731-742 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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