Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay
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Abstract
A universal PCR assay for bacteria and fungi detected meningitis pathogens in 65% of 20 cerebrospinal fluid (CSF) samples from patients with suspected central nervous system (CNS) infections compared to a 35% detection rate by culture and/or microscopy methods. Thus, the PCR assay can improve the diagnosis rate of infective meningitis when standard methods provide a negative result.
Bibliographical data
| Original language | English |
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| ISSN | 0095-1137 |
| DOIs | |
| Publication status | Published - 01.05.2014 |
| PubMed | 24622094 |
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