Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay

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Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay. / Meyer, T; Franke, G; Polywka, S K A; Lütgehetmann, M; Gbadamosi, J; Magnus, T; Aepfelbacher, M.

In: J CLIN MICROBIOL, Vol. 52, No. 5, 01.05.2014, p. 1751-3.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{33a3c21f01bd411ab21dd06cca5a45d5,
title = "Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay",
abstract = "A universal PCR assay for bacteria and fungi detected meningitis pathogens in 65% of 20 cerebrospinal fluid (CSF) samples from patients with suspected central nervous system (CNS) infections compared to a 35% detection rate by culture and/or microscopy methods. Thus, the PCR assay can improve the diagnosis rate of infective meningitis when standard methods provide a negative result.",
author = "T Meyer and G Franke and Polywka, {S K A} and M L{\"u}tgehetmann and J Gbadamosi and T Magnus and M Aepfelbacher",
year = "2014",
month = may,
day = "1",
doi = "10.1128/JCM.00469-14",
language = "English",
volume = "52",
pages = "1751--3",
journal = "J CLIN MICROBIOL",
issn = "0095-1137",
publisher = "American Society for Microbiology",
number = "5",

}

RIS

TY - JOUR

T1 - Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay

AU - Meyer, T

AU - Franke, G

AU - Polywka, S K A

AU - Lütgehetmann, M

AU - Gbadamosi, J

AU - Magnus, T

AU - Aepfelbacher, M

PY - 2014/5/1

Y1 - 2014/5/1

N2 - A universal PCR assay for bacteria and fungi detected meningitis pathogens in 65% of 20 cerebrospinal fluid (CSF) samples from patients with suspected central nervous system (CNS) infections compared to a 35% detection rate by culture and/or microscopy methods. Thus, the PCR assay can improve the diagnosis rate of infective meningitis when standard methods provide a negative result.

AB - A universal PCR assay for bacteria and fungi detected meningitis pathogens in 65% of 20 cerebrospinal fluid (CSF) samples from patients with suspected central nervous system (CNS) infections compared to a 35% detection rate by culture and/or microscopy methods. Thus, the PCR assay can improve the diagnosis rate of infective meningitis when standard methods provide a negative result.

U2 - 10.1128/JCM.00469-14

DO - 10.1128/JCM.00469-14

M3 - SCORING: Journal article

C2 - 24622094

VL - 52

SP - 1751

EP - 1753

JO - J CLIN MICROBIOL

JF - J CLIN MICROBIOL

SN - 0095-1137

IS - 5

ER -