Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay
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Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay. / Meyer, T; Franke, G; Polywka, S K A; Lütgehetmann, M; Gbadamosi, J; Magnus, T; Aepfelbacher, M.
in: J CLIN MICROBIOL, Jahrgang 52, Nr. 5, 01.05.2014, S. 1751-3.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay
AU - Meyer, T
AU - Franke, G
AU - Polywka, S K A
AU - Lütgehetmann, M
AU - Gbadamosi, J
AU - Magnus, T
AU - Aepfelbacher, M
PY - 2014/5/1
Y1 - 2014/5/1
N2 - A universal PCR assay for bacteria and fungi detected meningitis pathogens in 65% of 20 cerebrospinal fluid (CSF) samples from patients with suspected central nervous system (CNS) infections compared to a 35% detection rate by culture and/or microscopy methods. Thus, the PCR assay can improve the diagnosis rate of infective meningitis when standard methods provide a negative result.
AB - A universal PCR assay for bacteria and fungi detected meningitis pathogens in 65% of 20 cerebrospinal fluid (CSF) samples from patients with suspected central nervous system (CNS) infections compared to a 35% detection rate by culture and/or microscopy methods. Thus, the PCR assay can improve the diagnosis rate of infective meningitis when standard methods provide a negative result.
U2 - 10.1128/JCM.00469-14
DO - 10.1128/JCM.00469-14
M3 - SCORING: Journal article
C2 - 24622094
VL - 52
SP - 1751
EP - 1753
JO - J CLIN MICROBIOL
JF - J CLIN MICROBIOL
SN - 0095-1137
IS - 5
ER -