Prof.Dr. ID: 66906
Klaus Pantel
Publications
- 2012
Zirkulierende Tumorzellen in Krebspatienten als neuer Biomarker
Gorges, T., Riethdorf, S. & Pantel, K., 2012, In: J Onkologie. 7, p. 184-188 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells
Grabinski, N., Bartkowiak, K., Grupp, K., Brandt, B., Pantel, K. & Jücker, M., 12.2011, In: CELL SIGNAL. 23, 12, p. 1952-1960 9 p., 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression.
Kornfeld, J., Meder, S., Wohlberg, M., Friedrich, R., Rau, T., Riethdorf, L., Löning, T., Pantel, K. & Riethdorf, S., 04.01.2011, In: BRIT J CANCER. 104, 1, p. 138-145 8 p., 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Apoptosis-related deregulation of proteolytic activities and high serum levels of circulating nucleosomes and DNA in blood correlate with breast cancer progression.
Roth, C., Pantel, K., Müller, V., Rack, B., Kasimir-Bauer, S., Janni, W. & Schwarzenbach, H., 2011, In: BMC CANCER. 11, p. 4Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue.
Hein, S., Müller, V., Köhler, N., Wikman, H., Krenkel, S., Streichert, T., Schweizer, M., Riethdorf, S., Assmann, V., Henningsen, M., Beck, K., Issa, R., Jänicke, F., Pantel, K. & Milde-Langosch, K., 2011, In: BREAST CANCER RES TR. 129, 2, p. 347-360 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cell-free nucleic acids as biomarkers in cancer patients.
Schwarzenbach, H., Hoon, D. S. B. & Pantel, K., 2011, In: NAT REV CANCER. 11, 6, p. 426-437 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating cancer cells and their clinical applications.
Diamandis, E. P., Pantel, K., Scher, H. I., Terstappen, L. & Lianidou, E., 2011, In: CLIN CHEM. 57, 11, p. 1478-1484 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating microRNAs: promising breast cancer biomarkers - author´s response
Roth, C., Rack, B., Müller, V., Janni, W., Pantel, K. & Schwarzenbach, H., 2011, In: BREAST CANCER RES. 13, 1, p. 403Research output: SCORING: Contribution to journal › Newspaper articles › Transfer
Circulating tumor cell isolation and diagnostics: toward routine clinical use.
van de Stolpe, A., Pantel, K., Sleijfer, S., Terstappen, L. W., Toonder, D. & Jaap, M. J., 2011, In: CANCER RES. 71, 18, p. 5955-5960 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating tumors cells as biomarkers: progress toward biomarker qualification.
Danila, D. C., Pantel, K., Fleisher, M. & Scher, H. I., 2011, In: CANCER J. 17, 6, p. 438-450 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical relevance and biology of circulating tumor cells.
Bednarz, N., Alix-Panabières, C. & Pantel, K., 2011, In: BREAST CANCER RES. 13, 6, p. 228 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Controversies in clinical cancer dormancy.
Uhr, J. W. & Pantel, K., 2011, In: P NATL ACAD SCI USA. 108, 30, p. 12396-12400 30.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection and clinical relevance of early disseminated breast cancer cells depend on their cytokeratin expression pattern.
Harms-Effenberger, K., Borgen, E., Zu Eulenburg, C. G., Bartkowiak, K., Grosser, A., Synnestvedt, M., Kaaresen, R., Brandt, B., Nesland, J. M., Pantel, K. & Naume, B., 2011, In: BREAST CANCER RES TR. 125, 3, p. 729-738 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of circulating tumor cells by RT-PCR significantly associated with poor prognosis in breast cancer.
Zhang, L., Wu, G. & Pantel, K., 2011, In: BREAST CANCER RES TR. 130, 1, p. 359-364 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of circulating tumour cells in peripheral blood of patients with advanced non-metastatic bladder cancer.
Rink, M., Chun, F., Minner, S. J. P., Friedrich, M., Mauermann, O., Heinzer, H., Huland, H., Fisch, M., Pantel, K. & Riethdorf, S., 2011, In: BJU INT. 107, 10, p. 1668-1675 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disseminated tumor cells in the bone marrow of patients with ductal carcinoma in situ.
Sänger, N., Harms-Effenberger, K., Riethdorf, S., Viviane, V. H., Gauwerky, J., Wiegratz, I., Strebhardt, K., Kaufmann, M. & Pantel, K., 2011, In: INT J CANCER. 129, 10, p. 2522-2526 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy.
Minner, S. J. P., Enodien, M., Sirma, H., Lübke, A., Krohn, A., Mayer, P. S., Simon, R., Tennstedt, P., Müller, J., Scholz, L., Brase, J. C., Liu, A. Y., Schlüter, H., Pantel, K., Schumacher, U., Bokemeyer, C., Steuber, T., Graefen, M., Sauter, G. & Schlomm, T., 2011, In: CLIN CANCER RES. 17, 18, p. 5878-5888 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evaluation of cell-free tumour DNA and RNA in patients with breast cancer and benign breast disease.
Schwarzenbach, H., Müller, V., Milde-Langosch, K., Steinbach, B. & Pantel, K., 2011, In: MOL BIOSYST. 7, 10, p. 2848-2854 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genomic profiling of cell-free DNA in blood and bone marrow of prostate cancer patients.
Schwarzenbach, H., Chun, F., Isbarn, H., Huland, H. & Pantel, K., 2011, In: J CANCER RES CLIN. 137, 5, p. 811-819 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of platinum-based chemotherapy on circulating nucleic acid levels, protease activities in blood and disseminated tumor cells in bone marrow of ovarian cancer patients.
Wimberger, P., Roth, C., Pantel, K., Kasimir-Bauer, S., Kimmig, R. & Schwarzenbach, H., 2011, In: INT J CANCER. 128, 11, p. 2572-2580 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular mechanisms of metastasis.
Hoon, D. S. B., Ferris, R., Tanaka, R., Chong, K. K., Alix-Panabières, C. & Pantel, K., 2011, In: J SURG ONCOL. 103, 6, p. 508-517 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Persistence of disseminated tumor cells in the bone marrow of breast cancer patients predicts increased risk for relapse--a European pooled analysis.
Janni, W., Vogl, F. D., Wiedswang, G., Synnestvedt, M., Fehm, T., Jückstock, J., Borgen, E., Rack, B., Braun, S., Sommer, H., Solomayer, E., Pantel, K., Nesland, J., Friese, K. & Naume, B., 2011, In: CLIN CANCER RES. 17, 9, p. 2967-2976 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prospective evaluation of serum tissue inhibitor of metalloproteinase 1 and carbonic anhydrase IX in correlation to circulating tumor cells in patients with metastatic breast cancer.
Müller, V., Riethdorf, S., Rack, B., Janni, W., Fasching, P. A., Solomayer, E., Aktas, B., Kasimir-Bauer, S., Zeitz, J., Pantel, K., Fehm, T. & Group, DETECT. S., 2011, In: BREAST CANCER RES. 13, 4, p. 71 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prospective multi-centre study to validate chromogenic in situ hybridisation for the assessment of HER2 gene amplification in specimens from adjuvant and metastatic breast cancer patients.
Riethdorf, S., Hoegel, B., John, B., Ott, G., Fritz, P., Thon, S., Löning, T. & Pantel, K., 2011, In: J CANCER RES CLIN. 137, 2, p. 261-269 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative high-resolution genomic analysis of single cancer cells.
Hannemann, J., Meyer-Staeckling, S., Kemming, D., Alpers, I., Joosse, S., Pospisil, H., Kurtz, S., Görndt, J., Püschel, K., Riethdorf, S., Pantel, K. & Brandt, B., 2011, In: PLOS ONE. 6, 11, p. 26362 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Screening for circulating nucleic acids and caspase activity in the peripheral blood as potential diagnostic tools in lung cancer.
Roth, C., Kasimir-Bauer, S., Pantel, K. & Schwarzenbach, H., 2011, In: MOL ONCOL. 5, 3, p. 281-291 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The anti-interleukin-6 antibody siltuximab down-regulates genes implicated in tumorigenesis in prostate cancer patients from a phase I study.
Karkera, J., Steiner, H., Li, W., Skradski, V., Moser, P. L., Riethdorf, S., Reddy, M., Puchalski, T., Safer, K., Prabhakar, U., Pantel, K., Qi, M. & Culig, Z., 2011, In: PROSTATE. 71, 13, p. 1455-1465 13.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The GNAS1 T393C single nucleotide polymorphism predicts the natural postoperative course of complete resected esophageal cancer.
Vashist, Y., Kutup, A., Musici, S., Yekebas, E. F., Mina, S., Uzunoglu, F. G., Zehler, O., König, A., Cataldegirmen, G., Bockhorn, M., Harms-Effenberger, K., Kalinin, V., Pantel, K. & Izbicki, J. R., 2011, In: MOL CELL ONCOL. 34, 4, p. 281-288 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
VCAM-1 promotes osteolytic expansion of indolent bone micrometastasis of breast cancer by engaging α4β1-positive osteoclast progenitors.
Lu, X., Mu, E., Wei, Y., Riethdorf, S., Yang, Q., Yuan, M., Yan, J., Hua, Y., Tiede, B. J., Lu, X., Haffty, B. G., Pantel, K., Massagué, J. & Kang, Y., 2011, In: CANCER CELL. 20, 6, p. 701-714 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Advancing personalized cancer therapy by detection and characterization of circulating carcinoma cells.
Riethdorf, S. & Pantel, K., 2010, In: ANN NY ACAD SCI. 1210, p. 66-77Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
BRCA1 loss preexisting in small subpopulations of prostate cancer is associated with advanced disease and metastatic spread to lymph nodes and peripheral blood
Bednarz, N., Eltze, E., Semjonow, A., Rink, M., Andreas, A., Mulder, L., Hannemann, J., Fisch, M., Pantel, K., Weier, H-U. G., Bielawski, K. P. & Brandt, B., 2010, In: CLIN CANCER RES. 16, 13, p. 3340-3348 9 p., 13.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating microRNAs as blood-based markers for patients with primary and metastatic breast cancer.
Roth, C., Rack, B., Müller, V., Janni, W., Pantel, K. & Schwarzenbach, H., 2010, In: BREAST CANCER RES. 12, 6, p. 90 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating tumour cells in cancer patients: challenges and perspectives.
Pantel, K. & Alix-Panabières, C., 2010, In: TRENDS MOL MED. 16, 9, p. 398-406 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial.
Riethdorf, S., Müller, V., Zhang, L., Rau, T., Loibl, S., Komor, M., Roller, M., Huober, J., Fehm, T., Schrader, I., Hilfrich, J., Holms, F., Tesch, H., Eidtmann, H., Untch, M., von Minckwitz, G. & Pantel, K., 2010, In: CLIN CANCER RES. 16, 9, p. 2634-2645 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Discovery of a novel unfolded protein response phenotype of cancer stem/progenitor cells from the bone marrow of breast cancer patients.
Bartkowiak, K., Harms-Effenberger, K., Harder, S., Andreas, A., Buck, F., Peter-Katalinic, J., Pantel, K. & Brandt, B., 2010, In: J PROTEOME RES. 9, 6, p. 3158-3168 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HER2 status of circulating tumor cells in patients with metastatic breast cancer: a prospective, multicenter trial.
Fehm, T., Müller, V., Aktas, B., Janni, W., Schneeweiss, A., Stickeler, E., Lattrich, C., Löhberg, C. R., Solomayer, E., Rack, B., Riethdorf, S., Klein, C., Schindlbeck, C., Brocker, K., Kasimir-Bauer, S., Wallwiener, D. & Pantel, K., 2010, In: BREAST CANCER RES TR. 124, 2, p. 403-412 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increase in circulating microRNA levels in blood of ovarian cancer patients
Roth, C., Kasimir-Bauer, S., Heubner, M., Pantel, K. & Schwarzenbach, H., 2010, Circulating nucleic acids in plasma and serum. Gahan, P. (ed.). 1. ed. Springer, Vol. Ad. Exp. Med. Biol.. p. 63-71Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Insights into minimal residual disease in cancer patients: implications for anti-cancer therapies.
Müller, V., Alix-Panabières, C. & Pantel, K., 2010, In: EUR J CANCER. 46, 7, p. 1189-1197 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Insulin-like growth factor-1 receptor as a novel prognostic marker and its implication as a cotarget in the treatment of human adenocarcinoma of the esophagus.
Kalinina, T., Bockhorn, M., Kaifi, J., Thieltges, S., Güngör, C., Harms-Effenberger, K., Strelow, A., Reichelt, U., Sauter, G., Pantel, K., Izbicki, J. R. & Yekebas, E. F., 2010, In: INT J CANCER. 127, 8, p. 1931-1940 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular analysis of the polymorphisms of thymidylate synthase on cell-free circulating DNA in blood of patients with advanced colorectal carcinoma.
Schwarzenbach, H., Goekkurt, E., Pantel, K., Aust, D. E. & Stoehlmacher, J., 2010, In: INT J CANCER. 127, 4, p. 881-888 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Promoter- and cell-specific epigenetic regulation of CD44, Cyclin D2, GLIPR1 and PTEN by methyl-CpG binding proteins and histone modifications.
Müller, I., Wischnewski, F., Pantel, K. & Schwarzenbach, H., 2010, In: BMC CANCER. 10, p. 297Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PSA and Prostate
Schwarzenbach, H. & Pantel, K., 2010, PSA and Prostate: Circulating cell-free blood nucleic acids as a potential molecular marker for prostate cancer. Nova Science Publishers, p. 65-85Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
What's new on circulating tumor cells? A meeting report.
Lianidou, E. S., Mavroudis, D., Sotiropoulou, G., Agelaki, S. & Pantel, K., 2010, In: BREAST CANCER RES. 12, 4, p. 307 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Bone marrow aspiration for disseminated tumor cell detection: a must-have test or is the jury still out?
Scher, H. I. & Pantel, K., 2009, In: J CLIN ONCOL. 27, 10, p. 1531-1533 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer micrometastases.
Pantel, K., Alix-Panabières, C. & Riethdorf, S., 2009, In: NAT REV CLIN ONCOL. 6, 6, p. 339-351 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cell-free tumor DNA in blood plasma as a marker for circulating tumor cells in prostate cancer.
Schwarzenbach, H., Alix-Panabières, C., Müller, I., Letang, N., Vendrell, J-P., Rebillard, X. & Pantel, K., 2009, In: CLIN CANCER RES. 15, 3, p. 1032-1038 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical relevance and current challenges of research on disseminating tumor cells in cancer patients.
Riethdorf, S. & Pantel, K., 2009, In: BREAST CANCER RES. 11, 3, p. 10 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical Relevance of Disseminated Tumor Cells in Bone Marrow and Circulating Tumor Cells in the Blood of Breast Cancer Patients
Müller, V., Fehm, T., Janni, W., Gebauer, G., Solomayer, E. & Pantel, K., 2009, In: BREAST CARE. 4, 5, p. 333-338 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparative evaluation of cell-free tumor DNA in blood and disseminated tumor cells in bone marrow of patients with primary breast cancer.
Schwarzenbach, H., Pantel, K., Kemper, B., Beeger, C., Otterbach, F., Kimmig, R. & Kasimir-Bauer, S., 2009, In: BREAST CANCER RES. 11, 5, p. 71 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of bone marrow, disseminated tumour cells and blood-circulating tumour cells in breast cancer patients after primary treatment.
Slade M, J., Payne, R., Riethdorf, S., Ward, B., Zaidi S, A. A., Stebbing, J., Palmieri, C., Sinnett, H. D., Kulinskaya, E., Pitfield, T., McCormack, R. T., Pantel, K. & Coombes, R. C., 2009, In: BRIT J CANCER. 100, 1, p. 160-166 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review