Research ExplorerScientific StaffKlaus Pantel Publications

Prof.Dr. ID: 66906

Klaus Pantel

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Publications

  1. 2013

  2. Real-time liquid biopsy: circulating tumor cells versus circulating tumor DNA

    Alix-Panabières, C. & Pantel, K., 07.2013, In: J TRANSL MED. 1, 2, p. 18

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay

    Baccelli, I., Schneeweiss, A., Riethdorf, S., Stenzinger, A., Schillert, A., Vogel, V., Klein, C., Saini, M., Bäuerle, T., Wallwiener, M., Holland-Letz, T., Höfner, T., Sprick, M., Scharpff, M., Marmé, F., Sinn, H. P., Pantel, K., Weichert, W. & Trumpp, A., 01.06.2013, In: NAT BIOTECHNOL. 31, 6, p. 539-44 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Tracking tumor resistance using 'liquid biopsies'

    Pantel, K., Diaz, L. A. & Polyak, K., 01.06.2013, In: NAT MED. 19, 6, p. 676-677 2 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  5. Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing

    Heitzer, E., Auer, M., Gasch, C., Pichler, M., Ulz, P., Hoffmann, E. M., Lax, S., Waldispuehl-Geigl, J., Mauermann, O., Lackner, C., Höfler, G., Eisner, F., Sill, H., Samonigg, H., Pantel, K., Riethdorf, S., Bauernhofer, T., Geigl, J. B. & Speicher, M. R., 15.05.2013, In: CANCER RES. 73, 10, p. 2965-75 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Tumor cell dissemination: emerging biological insights from animal models and cancer patients

    Kang, Y. & Pantel, K., 13.05.2013, In: CANCER CELL. 23, 5, p. 573-81 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Plastin3 is a novel marker for circulating tumor cells undergoing the epithelial-mesenchymal transition and is associated with colorectal cancer prognosis

    Yokobori, T., Iinuma, H., Shimamura, T., Imoto, S., Sugimachi, K., Ishii, H., Iwatsuki, M., Ota, D., Ohkuma, M., Iwaya, T., Nishida, N., Kogo, R., Sudo, T., Tanaka, F., Shibata, K., Toh, H., Sato, T., Barnard, G. F., Fukagawa, T., Yamamoto, S., Nakanishi, H., Sasaki, S., Miyano, S., Watanabe, T., Kuwano, H., Mimori, K., Pantel, K. & Mori, M., 01.04.2013, In: CANCER RES. 73, 7, p. 2059-69 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Frequent intratumoral heterogeneity of EGFR gene copy gain in non-small cell lung cancer

    Grob, T. J., Hoenig, T., Clauditz, T. S., Atanackovic, D., Koenig, A. M., Vashist, Y. K., Klose, H., Simon, R., Pantel, K., Izbicki, J. R., Bokemeyer, C., Sauter, G. & Wilczak, W., 01.03.2013, In: LUNG CANCER. 79, 3, p. 221-7 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. CXCR7 expression in esophageal cancer

    Tachezy, M., Zander, H., Gebauer, F., Loga, K., Pantel, K., Izbicki, J. R. & Bockhorn, M., 01.01.2013, In: J TRANSL MED. 11, p. 238

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Heterogeneity of estrogen receptor expression in circulating tumor cells from metastatic breast cancer patients

    Babayan, A., Hannemann, J., Spötter, J., Müller, V., Pantel, K. & Joosse, S. A., 01.01.2013, In: PLOS ONE. 8, 9, p. e75038

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing

    Heitzer, E., Ulz, P., Belic, J., Gutschi, S., Quehenberger, F., Fischereder, K., Benezeder, T., Auer, M., Pischler, C., Mannweiler, S., Pichler, M., Eisner, F., Haeusler, M., Riethdorf, S., Pantel, K., Samonigg, H., Hoefler, G., Augustin, H., Geigl, J. B. & Speicher, M. R., 01.01.2013, In: GENOME MED. 5, 4, p. 30

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Biologic challenges in the detection of circulating tumor cells.

    Joosse, S. A. & Pantel, K., 2013, In: CANCER RES. 73, 1, p. 8-11 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Circulating tumor cells as therapy-related biomarkers in cancer patients.

    Gorges, T. & Pantel, K., 2013, In: CANCER IMMUNOL IMMUN. 62, 5, p. 931-939 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Circulating tumor cells: liquid biopsy of cancer.

    Alix-Panabières, C. & Pantel, K., 2013, In: CLIN CHEM. 59, 1, p. 110-118 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Correction: Involvement of CXCR4 Chemokine Receptor in Metastastic HER2-Positive Esophageal Cancer

    Gros, S. J., Kurschat, N., Drenckhan, A., Dohrmann, T. W., Forberich, E., Harms-Effenberger, K., Reichelt, U., Hoffmann, R. M., Pantel, K., Kaifi, J. T. & Izbicki, J., 2013, In: PLOS ONE. 8, 5

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  16. Definition of molecular determinants of prostate cancer cell bone extravasation.

    Barthel, S. R., Hays, D. L., Yazawa, E. M., Opperman, M., Walley, K. C., Nimrichter, L., Burdick, M. M., Gillard, B. M., Moser, M. T., Pantel, K., Foster, B. A., Pienta, K. J. & Dimitroff, C. J., 2013, In: CANCER RES. 73, 2, p. 942-952 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer.

    Gasch, C., Bauernhofer, T., Pichler, M., Langer-Freitag, S., Reeh, M., Seifert, A. M., Mauermann, O., Izbicki, J. R., Pantel, K. & Riethdorf, S., 2013, In: CLIN CHEM. 59, 1, p. 252-260 9 p., 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression.

    Otto, B., Gruner, K., Heinlein, C., Wegwitz, F., Nollau, P., Ylstra, B., Pantel, K., Schumacher, U., Baumbusch, L. O., Martin-Subero, J. I., Siebert, R., Wagener, C., Streichert, T., Deppert, W. & Tolstonog, G. V., 2013, In: INT J CANCER. 132, 6, p. 1300-1310 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. The prognostic impact of circulating tumor cells in subtypes of metastatic breast cancer.

    Wallwiener, M., Hartkopf, A. D., Baccelli, I., Riethdorf, S., Schott, S., Pantel, K., Marmé, F., Sohn, C., Trumpp, A., Rack, B., Aktas, B., Solomayer, E-F., Müller, V., Janni, W., Schneeweiss, A. & Fehm, T. N., 2013, In: BREAST CANCER RES TR. 137, 2, p. 503-510 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. 2012

  21. VEGFR-1 expression levels predict occurrence of disseminated tumor cells in the bone marrow of patients with esophageal carcinoma

    Schultze, A., Ben-Batalla, I., Riethdorf, S., Bubenheim, M., Yekebas, E. F., Erbersdobler, A., Reichelt, U., Harms-Effenberger, K., Schmidt, T., Izbicki, J. R., Bokemeyer, C., Pantel, K., Fiedler, W. & Loges, S., 12.2012, In: CLIN EXP METASTAS. 29, 8, p. 879-887 9 p., 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. ALCAM (CD166) expression and serum levels are markers for poor survival of esophageal cancer patients

    Tachezy, M., Harms-Effenberger, K., Zander, H., Minner, S. J. P., Gebauer, F., Vashist, Y., Sauter, G., Pantel, K., Izbicki, J. R. & Bockhorn, M., 15.07.2012, In: INT J CANCER. 131, 2, p. 396-405 10 p., 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. The interplay of HER2/HER3/PI3K and EGFR/HER2/PLC-γ1 signalling in breast cancer cell migration and dissemination

    Balz, L. M., Bartkowiak, K., Andreas, A., Pantel, K., Niggemann, B., Zänker, K. S., Brandt, B. & Dittmar, T., 06.2012, In: J PATHOL. 227, 2, p. 234-244 11 p., 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. 15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.

    Lehtinen, L., Vainio, P., Wikman, H., Reemts, J., Hilvo, M., Issa, R., Pollari, S., Brandt, B., Oresic, M., Pantel, K., Kallioniemi, O. & Iljin, K., 2012, In: J PATHOL. 226, 4, p. 674-686 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Changes in keratin expression during metastatic progression of breast cancer: impact on the detection of circulating tumor cells.

    Joosse, S., Hannemann, J., Spötter, J., Bauche, A., Andreas, A., Müller, V. & Pantel, K., 2012, In: CLIN CANCER RES. 18, 4, p. 993-1003 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Circulating epithelial cells in patients with benign colon diseases.

    Pantel, K., Denève, E., Nocca, D., Coffy, A., Vendrell, J-P., Maudelonde, T., Riethdorf, S. & Alix-Panabières, C., 2012, In: CLIN CHEM. 58, 5, p. 936-940 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Circulating miRNAs as surrogate markers for circulating tumor cells and prognostic markers in metastatic breast cancer.

    Madhavan, D., Zucknick, M., Wallwiener, M., Cuk, K., Modugno, C., Scharpff, M., Schott, S., Heil, J., Turchinovich, A., Yang, R., Benner, A., Riethdorf, S., Trumpp, A., Sohn, C., Pantel, K., Schneeweiss, A. & Burwinkel, B., 2012, In: CLIN CANCER RES. 18, 21, p. 5972-5982 21.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Circulating tumor cells and circulating tumor DNA.

    Alix-Panabières, C., Schwarzenbach, H. & Pantel, K., 2012, In: ANNU REV MED. 63, p. 199-215

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Circulating tumor-derived biomarkers in lung cancer.

    Tänzer, A., Alix-Panabières, C., Wikman, H. & Pantel, K., 2012, In: J THORAC DIS. 4, 5, p. 448-449 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases.

    Wikman, H., Sielaff-Frimpong, B., Kropidlowski, J., Witzel, I., Milde-Langosch, K., Sauter, G., Westphal, M., Lamszus, K. & Pantel, K., 2012, In: PLOS ONE. 7, 10, p. 47537 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Considerations in the development of circulating tumor cell technology for clinical use.

    Parkinson, D. R., Dracopoli, N., Petty, B. G., Compton, C., Cristofanilli, M., Deisseroth, A., Hayes, D. F., Kapke, G., Kumar, P., Lee, J. S., Liu, M. C., McCormack, R., Mikulski, S., Nagahara, L., Pantel, K., Pearson-White, S., Punnoose, E. A., Roadcap, L. T., Schade, A. E., Scher, H. I., Sigman, C. C. & Kelloff, G. J., 2012, In: J TRANSL MED. 10, p. 138

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Detection methods of circulating tumor cells.

    Pantel, K. & Alix-Panabières, C., 2012, In: J THORAC DIS. 4, 5, p. 446-447 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Diagnostic potential of PTEN-targeting miR-214 in the blood of breast cancer patients.

    Schwarzenbach, H., Milde-Langosch, K., Steinbach, B., Müller, V. & Pantel, K., 2012, In: BREAST CANCER RES TR. 134, 3, p. 933-941 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Disseminated tumor cells in bone marrow and the natural course of resected esophageal cancer.

    Vashist, Y., Harms-Effenberger, K., Vettorazzi, E., Riethdorf, S., Yekebas, E. F., Izbicki, J. R. & Pantel, K., 2012, In: ANN SURG. 255, 6, p. 1105-1112 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Disseminated tumor cells in pancreatic cancer-an independent prognosticator of disease progression and survival.

    Harms-Effenberger, K., Schröder, C., Zu Eulenburg, C. G., Reeh, M., Tachezy, M., Riethdorf, S., Vashist, Y., Izbicki, J. R., Pantel, K. & Bockhorn, M., 2012, In: INT J CANCER. 131, 4, p. 475-483 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer.

    Mathiesen, R. R., Fjelldal, R., Liestøl, K., Due, E. U., Geigl, J. B., Riethdorf, S., Borgen, E., Rye, I. H., Schneider, I. J., Obenauf, A. C., Mauermann, O., Nilsen, G., Ole, C. L., Børresen-Dale, A-L., Pantel, K., Speicher, M. R., Naume, B. & Baumbusch, L. O., 2012, In: INT J CANCER. 131, 4, p. 405-415 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Immunocytochemical detection and characterisation of individual micrometastatic tumour cells.

    Braun, S. & Pantel, K., 2012, In: Methods Mol Biol. 878, p. 63-70

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Involvement of CXCR4 chemokine receptor in metastastic HER2-positive esophageal cancer.

    Gros, S., Kurschat, N., Drenckhan, A., Dohrmann, T., Forberich, E., Harms-Effenberger, K., Reichelt, U., Hoffman, R. M., Pantel, K., Kaifi, J. & Izbicki, J. R., 2012, In: PLOS ONE. 7, 10, p. 47287 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Loss of heterozygosity at tumor suppressor genes detectable on fractionated circulating cell-free tumor DNA as indicator of breast cancer progression.

    Schwarzenbach, H., Eichelser, C., Kropidlowski, J., Janni, W., Rack, B. & Pantel, K., 2012, In: CLIN CANCER RES. 18, 20, p. 5719-5730 20.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Low levels of cell-free circulating miR-361-3p and miR-625* as blood-based markers for discriminating malignant from benign lung tumors.

    Roth, C., Stückrath, I., Pantel, K., Izbicki, J. R., Tachezy, M. & Schwarzenbach, H., 2012, In: PLOS ONE. 7, 6, p. 38248 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Meta-analysis of the prognostic value of circulating tumor cells in breast cancer.

    Zhang, L., Riethdorf, S., Wu, G., Wang, T., Yang, K., Peng, G., Liu, J. & Pantel, K., 2012, In: CLIN CANCER RES. 18, 20, p. 5701-5710 20.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Minimal residual disease and circulating tumor cells in breast cancer: open questions for research.

    Ignatiadis, M., Sotiriou, C. & Pantel, K., 2012, In: Recent Results Cancer Res. 195, p. 3-9

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Opposite roles of FOXA1 and NKX2-1 in lung cancer progression.

    Deutsch, L., Wrage, M., Koops, S., Glatzel, M., Uzunoglu, F. G., Kutup, A., Hinsch, A., Sauter, G., Izbicki, J. R., Pantel, K. & Wikman, H., 2012, In: GENE CHROMOSOME CANC. 51, 6, p. 618-629 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Plasticity of disseminating cancer cells in patients with epithelial malignancies.

    Bednarz, N., Alix-Panabières, C. & Pantel, K., 2012, In: CANCER METAST REV. 31, 3-4, p. 673-687 3-4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Prognostic impact of circulating tumor cells assessed with the CellSearch System™ and AdnaTest Breast™ in metastatic breast cancer patients: the DETECT study.

    Müller, V., Riethdorf, S., Rack, B., Janni, W., Fasching, P. A., Solomayer, E., Aktas, B., Kasimir-Bauer, S., Pantel, K., Fehm, T. & Group, O. B. O. T. DETECT. S., 2012, In: BREAST CANCER RES. 14, 4, p. 118 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. Prognostic role and HER2 expression of circulating tumor cells in peripheral blood of patients prior to radical cystectomy: a prospective study.

    Rink, M., Chun, F., Dahlem, R., Soave, A., Minner, S. J. P., Hansen, J., Stoupiec, M., Coith, C., Kluth, L., Ahyai, S., Friedrich, M. G., Shariat, S. F., Fisch, M., Pantel, K. & Riethdorf, S., 2012, In: EUR UROL. 61, 4, p. 810-817 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Relevance of PTEN loss in brain metastasis formation in breast cancer patients.

    Wikman, H., Lamszus, K., Detels, N., Uslar, L., Wrage, M., Benner, C., Hohensee, I., Ylstra, B., Eylmann, K., Zapatka, M., Sauter, G., Kemming, D., Glatzel, M., Müller, V., Westphal, M. & Pantel, K., 2012, In: BREAST CANCER RES. 14, 2, p. 49 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. The connectivity of lymphogenous and hematogenous tumor cell dissemination: biological insights and clinical implications.

    Sleeman, J. P., Cady, B. & Pantel, K., 2012, In: CLIN EXP METASTAS. 29, 7, p. 737-746 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. The current role of circulating tumor cells in the diagnosis and management of bone metastases in advanced prostate cancer.

    Saad, F. & Pantel, K., 2012, In: FUTURE ONCOL. 8, 3, p. 321-331 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. The interrelating dynamics of hypoxic tumor microenvironments and cancer cell phenotypes in cancer metastasis.

    Bartkowiak, K., Riethdorf, S. & Pantel, K., 2012, In: CANCER MICROENVIRON. 5, 1, p. 59-72 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. The potential of circulating tumor cells as a liquid biopsy to guide therapy in prostate cancer.

    Pantel, K. & Alix-Panabières, C., 2012, In: CANCER DISCOV. 2, 11, p. 974-975 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. Vascular endothelial growth factor receptor 2 gene polymorphisms as predictors for tumor recurrence and overall survival in non-small-cell lung cancer.

    Uzunoglu, F. G., Kaufmann, C., Wikman, H., Güngör, C., Bohn, B., Nentwich, M., Reeh, M., Pantel, K., Bockhorn, M., Kutup, A., Mann, O., Izbicki, J. R. & Vashist, Y., 2012, In: ANN SURG ONCOL. 19, 7, p. 2159-2168 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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