The GNAS1 T393C single nucleotide polymorphism predicts the natural postoperative course of complete resected esophageal cancer.

Yogesh Vashist; Asad Kutup; Safije Musici; Emre F. Yekebas; Sormeh Mina; Faik Güntac Uzunoglu; Oliver Zehler; Alexandra König; Güllü Cataldegirmen; Maximilian Bockhorn; Katharina Harms-Effenberger; Vjacheslav Kalinin; Klaus Pantel; Jakob R. Izbicki

doi:10.1007/s13402-011-0016-x

The GNAS1 T393C single nucleotide polymorphism predicts the natural postoperative course of complete resected esophageal cancer.

Yogesh Vashist
Asad Kutup
Safije Musici
Emre F. Yekebas
Sormeh Mina
Faik Güntac Uzunoglu
Oliver Zehler
Alexandra König
Güllü Cataldegirmen
Maximilian Bockhorn
Katharina Harms-Effenberger
Vjacheslav Kalinin
Klaus Pantel
Jakob R. Izbicki

Related Research units

Department of General, Visceral and Thoracic Surgery
Department of Tumor Biology

Abstract

Genetic variations in cancer patients may serve as important prognostic indicators of clinical outcome. The GNAS1 T393C single nucleotide polymorphism (SNP) diversely correlates with the clinical outcome in cancer. The aim of this study was to evaluate the potential prognostic value of T393C-SNP in complete resected only surgically treated esophageal cancer (EC).

Bibliographical data

Original language	English
Article number	4
ISSN	2372-3556
DOIs	https://doi.org/10.1007/s13402-011-0016-x
Publication status	Published - 2011

pubmed	21340746