Research ExplorerScientific StaffDiego Sepulveda-Falla Publications

MD PI / Group Leader ID: 49836

Diego Sepulveda-Falla

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ORCID: 0000-0003-0176-2042
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Publications

  1. 2024

  2. Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases

    Song, F., Kovac, V., Mohammadi, B., Littau, J. L., Scharfenberg, F., Matamoros Angles, A., Vanni, I., Shafiq, M., Orge, L., Galliciotti, G., Djakkani, S., Linsenmeier, L., Černilec, M., Hartman, K., Jung, S., Tatzelt, J., Neumann, J. E., Damme, M., Tschirner, S. K., Lichtenthaler, S. F., Ricklefs, F. L., Sauvigny, T., Schmitz, M., Zerr, I., Puig, B., Tolosa, E., Ferrer, I., Magnus, T., Rupnik, M. S., Sepulveda-Falla, D., Matschke, J., Šmid, L. M., Bresjanac, M., Andreoletti, O., Krasemann, S., Foliaki, S. T., Nonno, R., Becker-Pauly, C., Monzo, C., Crozet, C., Haigh, C. L., Glatzel, M., Curin Serbec, V. & Altmeppen, H. C., 09.07.2024, In: ACTA NEUROPATHOL. 148, 1, p. 2

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease

    Quiroz, Y. T., Aguillon, D., Aguirre-Acevedo, D. C., Vasquez, D., Zuluaga, Y., Baena, A. Y., Madrigal, L., Hincapié, L., Sanchez, J. S., Langella, S., Posada-Duque, R., Littau, J. L., Villalba-Moreno, N. D., Vila-Castelar, C., Ramirez Gomez, L., Garcia, G., Kaplan, E., Rassi Vargas, S., Ossa, J. A., Valderrama-Carmona, P., Perez-Corredor, P., Krasemann, S., Glatzel, M., Kosik, K. S., Johnson, K., Sperling, R. A., Reiman, E. M., Sepulveda-Falla, D., Lopera, F. & Arboleda-Velasquez, J. F., 20.06.2024, In: NEW ENGL J MED. 390, 23, p. 2156-2164 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer's disease profile and possible mechanisms of disease protection

    Almeida, M. C., Eger, S. J., He, C., Audouard, M., Nikitina, A., Glasauer, S. M. K., Han, D., Mejía-Cupajita, B., Acosta-Uribe, J., Villalba-Moreno, N. D., Littau, J. L., Elcheikhali, M., Rivera, E. K., Carrettiero, D. C., Villegas-Lanau, C. A., Sepulveda-Falla, D., Lopera, F. & Kosik, K. S., 05.06.2024, In: NEURON. 112, 11, p. 1778-1794.e7

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact

    Kalaria, R., Maestre, G., Mahinrad, S., Acosta, D. M., Akinyemi, R. O., Alladi, S., Allegri, R. F., Arshad, F., Babalola, D. O., Baiyewu, O., Bak, T. H., Bellaj, T., Brodie-Mends, D. K., Carrillo, M. C., Celestin, K-K-M., Damasceno, A., de Silva, R. K., de Silva, R., Djibuti, M., Dreyer, A. J., Ellajosyula, R., Farombi, T. H., Friedland, R. P., Garza, N., Gbessemehlan, A., Georgiou, E. E-Z., Govia, I., Grinberg, L. T., Guerchet, M., Gugssa, S. A., Gumikiriza-Onoria, J. L., Hogervorst, E., Hornberger, M., Ibanez, A., Ihara, M., Issac, T. G., Jönsson, L., Karanja, W. M., Lee, J. H., Leroi, I., Livingston, G., Manes, F. F., Mbakile-Mahlanza, L., Miller, B. L., Musyimi, C. W., Mutiso, V. N., Nakasujja, N., Ndetei, D. M., Nightingale, S., Novotni, G., Nyamayaro, P., Nyame, S., Ogeng'o, J. A., Ogunniyi, A., de Oliveira, M. O., Okubadejo, N. U., Orrell, M., Paddick, S-M., Pericak-Vance, M. A., Pirtosek, Z., Potocnik, F. C. V., Raman, R., Rizig, M., Rosselli, M., Salokhiddinov, M., Satizabal, C. L., Sepulveda-Falla, D., Seshadri, S., Sexton, C. E., Skoog, I., George-Hyslop, P. H. S., Suemoto, C. K., Thapa, P., Udeh-Momoh, C. T., Valcour, V., Vance, J. M., Varghese, M., Vera, J. H., Walker, R. W., Zetterberg, H., Zewde, Y. Z. & Ismail, O., 06.2024, In: ALZHEIMERS DEMENT. 20, 6, p. 4290-4314 25 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  6. Genetic modifiers of cognitive decline in PSEN1 E280A Alzheimer's disease

    Sepulveda-Falla, D., Vélez, J. I., Acosta-Baena, N., Baena, A., Moreno, S., Krasemann, S., Lopera, F., Mastronardi, C. A. & Arcos-Burgos, M., 04.2024, In: ALZHEIMERS DEMENT. 20, 4, p. 2873-2885 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation

    Marino, C., Perez-Corredor, P., O'Hare, M., Heuer, A., Chmielewska, N., Gordon, H., Chandrahas, A. S., Gonzalez-Buendia, L., Delgado-Tirado, S., Doan, T. H., Vanderleest, T. E., Arevalo-Alquichire, S., Obar, R. A., Ortiz-Cordero, C., Villegas, A., Sepulveda-Falla, D., Kim, L. A., Lopera, F., Mahley, R., Huang, Y., Quiroz, Y. T. & Arboleda-Velasquez, J. F., 02.2024, In: ALZHEIMERS DEMENT. 20, 2, p. 819-836 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer's cases

    Perez-Corredor, P., Vanderleest, T. E., Vacano, G. N., Sanchez, J. S., Villalba-Moreno, N. D., Marino, C., Krasemann, S., Mendivil-Perez, M. A., Aguillón, D., Jiménez-Del-Río, M., Baena, A., Sepulveda-Falla, D., Lopera, F., Quiroz, Y. T., Arboleda-Velasquez, J. F. & Mazzarino, R. C., 2024, In: FRONT MOL NEUROSCI. 17, p. 1373568

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. 2023

  10. Comorbidities in Early-Onset Sporadic versus Presenilin-1 Mutation-Associated Alzheimer's Disease Dementia: Evidence for Dependency on Alzheimer's Disease Neuropathological Changes

    Sepulveda-Falla, D., Villegas Lanau, C. A., White, C., Serrano, G. E., Acosta-Uribe, J., Mejía-Cupajita, B., Villalba-Moreno, N. D., Lu, P., Glatzel, M., Kofler, J. K., Ghetti, B., Frosch, M. P., Lopera Restrepo, F., Kosik, K. S. & Beach, T. G., 16.08.2023, In: medRxiv.

    Research output: SCORING: Contribution to journal › Preprint › Research

  11. Resistant and Resilient mutations in protection against familial Alzheimer's disease: learning from nature

    Sepulveda-Falla, D., 01.06.2023, In: MOL NEURODEGENER. 18, 1, p. 36

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics

    Panahi, M., Hase, Y., Gallart-Palau, X., Mitra, S., Watanabe, A., Low, R. C., Yamamoto, Y., Sepulveda-Falla, D., Hainsworth, A. H., Ihara, M., Sze, S. K., Viitanen, M., Behbahani, H. & Kalaria, R. N., 08.05.2023, In: ACTA NEUROPATHOL COM. 11, 1, p. 76

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man

    Lopera, F., Marino, C., Chandrahas, A. S., O'Hare, M., Villalba-Moreno, N. D., Aguillon, D., Baena, A., Sanchez, J. S., Vila-Castelar, C., Ramirez Gomez, L., Chmielewska, N., Oliveira, G. M., Littau, J. L., Hartmann, K., Park, K., Krasemann, S., Glatzel, M., Schoemaker, D., Gonzalez-Buendia, L., Delgado-Tirado, S., Arevalo-Alquichire, S., Saez-Torres, K. L., Amarnani, D., Kim, L. A., Mazzarino, R. C., Gordon, H., Bocanegra, Y., Villegas, A., Gai, X., Bootwalla, M., Ji, J., Shen, L., Kosik, K. S., Su, Y., Chen, Y., Schultz, A., Sperling, R. A., Johnson, K., Reiman, E. M., Sepulveda-Falla, D., Arboleda-Velasquez, J. F. & Quiroz, Y. T., 05.2023, In: NAT MED. 29, 5, p. 1243-1252 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. The Nairobi Declaration-Reducing the burden of dementia in low- and middle-income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs

    Maestre, G., Carrillo, M., Kalaria, R., Acosta, D., Adams, L., Adoukonou, T., Akinwande, K., Akinyemi, J., Akinyemi, R., Akpa, O., Alladi, S., Allegri, R., Arizaga, R., Arshad, F., Arulogun, O., Babalola, D., Baiyewu, O., Bak, T., Bellaj, T., Boshe, J., Brayne, C., Brodie-Mends, D., Brown, R., Cahn, J., Cyrille, N., Damasceno, A., de Silva, R., de Silva, R., Djibuti, M., Dreyer, A. J., Ellajosyula, R., Farombi, T., Fongang, B., Forner, S., Friedland, R., Garza, N., Gbessemehlan, A., Georgiou, E. E-Z., Gouider, R., Govia, I., Grinberg, L., Guerchet, M., Gugssa, S., Gumikiriza-Onoria, J. L., Gustafson, D., Hogervorst, E., Hornberger, M., Ibanez, A., Ihara, M., Ismail, O., Issac, T., Jönsson, L., Kaputu, C., Karanja, W., Karungi, J., Tshala-Katumbay, D., Kunkle, B., Lee, J. H., Leroi, I., Lewis, R., Livingston, G., Lopera, F., Lwere, K., Manes, F., Mbakile-Mahlanza, L., Mena, P., Miller, B., Millogo, A., Mohamed, A., Musyimi, C., Mutiso, V., Nakasujja, N., Ndetei, D., Nightingale, S., Njamnshi, A. K., Novotni, G., Nyamayaro, P., Nyame, S., Ogeng'o, J., Ogunniyi, A., Okada De Oliveira, M., Okubadejo, N., Orrell, M., Orunmuyi, A., Owolabi, M., Paddick, S., A Pericak-Vance, M., Pirtosek, Z., Potocnik, F., Preston, B., Raman, R., Ranchod, K., Rizig, M., Rosselli, M., Deepa, R., Roy, U., Salokhiddinov, M., Sano, M., Sarfo, F., Satizabal, C. L., Sepulveda-Falla, D., Seshadri, S., Sexton, C., Skoog, I., St George-Hyslop, P., Suemoto, C., Tanner, J., Thapa, P., Toure, K., Ucheagwu, V., Udeh-Momoh, C., Valcour, V., Vance, J., Varghese, M., Vera, J., Walker, R., Weidner, W., Sebastian, W., Whitehead Gay, P., Zetterberg, H., Zewde, Y. & African Dementia Consortium, 11.03.2023, In: ALZHEIMERS DEMENT. 19, 3, p. 1105-1108 4 p.

    Research output: SCORING: Contribution to journal › Editorial › Research

  15. Gliovascular alterations in sporadic and familial Alzheimer's disease: APOE3 Christchurch homozygote glioprotection

    Henao-Restrepo, J., López-Murillo, C., Valderrama-Carmona, P., Orozco-Santa, N., Gomez, J., Gutiérrez-Vargas, J., Moraga, R., Toledo, J., Littau, J. L., Härtel, S., Arboleda-Velásquez, J. F., Sepulveda-Falla, D., Lopera, F., Cardona-Gómez, G. P., Villegas, A. & Posada-Duque, R., 03.2023, In: BRAIN PATHOL. 33, 2, p. e13119

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Early Depressive Symptoms Predict Faster Dementia Progression in Autosomal-Dominant Alzheimer's Disease

    Acosta-Baena, N., Lopera-Gómez, C. M., Jaramillo-Elorza, M. C., Velilla-Jiménez, L., Villegas-Lanau, C. A., Sepúlveda-Falla, D., Arcos-Burgos, M. & Lopera, F., 2023, In: J ALZHEIMERS DIS. 92, 3, p. 911-923 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. 2022

  18. Evidence of beta amyloid independent small vessel disease in familial Alzheimer's disease

    Littau, J. L., Velilla, L., Hase, Y., Villalba-Moreno, N. D., Hagel, C., Drexler, D., Osorio Restrepo, S., Villegas, A., Lopera, F., Vargas, S., Glatzel, M., Krasemann, S., Quiroz, Y. T., Arboleda-Velasquez, J. F., Kalaria, R. & Sepulveda-Falla, D., 11.2022, In: BRAIN PATHOL. 32, 6, p. e13097

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Loss of Homeostatic Microglia Signature in Prion Diseases

    Wang, Y., Hartmann, K., Thies, E., Mohammadi, B., Altmeppen, H., Sepulveda-Falla, D., Glatzel, M. & Krasemann, S., 21.09.2022, In: CELLS-BASEL. 11, 19, 2948.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  20. Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia

    Sepulveda-Falla, D., Sanchez, J. S., Almeida, M. C., Boassa, D., Acosta-Uribe, J., Vila-Castelar, C., Ramirez-Gomez, L., Baena, A., Aguillon, D., Villalba-Moreno, N. D., Littau, J. L., Villegas, A., Beach, T. G., White, C. L., Ellisman, M., Krasemann, S., Glatzel, M., Johnson, K. A., Sperling, R. A., Reiman, E. M., Arboleda-Velasquez, J. F., Kosik, K. S., Lopera, F. & Quiroz, Y. T., 09.2022, In: ACTA NEUROPATHOL. 144, 3, p. 589-601 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

    Krasemann, S., Haferkamp, U., Pfefferle, S., Woo, M. S., Heinrich, F., Schweizer, M., Appelt-Menzel, A., Cubukova, A., Barenberg, J., Leu, J., Hartmann, K., Thies, E., Littau, J. L., Sepulveda-Falla, D., Zhang, L., Ton, K., Liang, Y., Matschke, J., Ricklefs, F., Sauvigny, T., Sperhake, J., Fitzek, A., Gerhartl, A., Brachner, A., Geiger, N., König, E-M., Bodem, J., Franzenburg, S., Franke, A., Moese, S., Müller, F-J., Geisslinger, G., Claussen, C., Kannt, A., Zaliani, A., Gribbon, P., Ondruschka, B., Neuhaus, W., Friese, M. A., Glatzel, M. & Pless, O., 08.02.2022, In: STEM CELL REP. 17, 2, p. 307-320 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Reactive Astrocytes Contribute to Alzheimer's Disease-Related Neurotoxicity and Synaptotoxicity in a Neuron-Astrocyte Co-culture Assay

    Wasilewski, D., Villalba-Moreno, N. D., Stange, I., Glatzel, M., Sepulveda-Falla, D. & Krasemann, S., 21.01.2022, In: FRONT CELL NEUROSCI. 15, 739411.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. 2021

  24. Cerebral Small Vessel Disease in Sporadic and Familial Alzheimer Disease

    Kalaria, R. N. & Sepulveda-Falla, D., 11.2021, In: AM J PATHOL. 191, 11, p. 1888-1905 18 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  25. Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators

    O'Hare, M., Amarnani, D., Whitmore, H. A. B., An, M., Marino, C., Ramos, L., Delgado-Tirado, S., Hu, X., Chmielewska, N., Chandrahas, A., Fitzek, A., Heinrich, F., Steurer, S., Ondruschka, B., Glatzel, M., Krasemann, S., Sepulveda-Falla, D., Lagares, D., Pedron, J., Bushweller, J. H., Liu, P., Arboleda-Velasquez, J. F. & Kim, L. A., 07.2021, In: AM J PATHOL. 191, 7, p. 1193-1208 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Protein Predictive Modeling and Simulation of Mutations of Presenilin-1 Familial Alzheimer's Disease on the Orthosteric Site

    Soto-Ospina, A., Araque Marín, P., Bedoya, G., Sepulveda-Falla, D. & Villegas Lanau, A., 02.06.2021, In: FRONT MOL BIOSCI. 8, 649990.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer's disease

    Sepulveda-Falla, D., Chavez-Gutierrez, L., Portelius, E., Vélez, J. I., Dujardin, S., Barrera-Ocampo, A., Dinkel, F., Hagel, C., Puig, B., Mastronardi, C., Lopera, F., Hyman, B. T., Blennow, K., Arcos-Burgos, M., de Strooper, B. & Glatzel, M., 02.2021, In: ACTA NEUROPATHOL. 141, 2, p. 217-233 17 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. 2020

  29. Cerebrospinal Fluid Mitochondrial DNA in Rapid and Slow Progressive Forms of Alzheimer's Disease

    Podlesniy, P., Llorens, F., Puigròs, M., Serra, N., Sepúlveda-Falla, D., Schmidt, C., Hermann, P., Zerr, I. & Trullas, R., 31.08.2020, In: INT J MOL SCI. 21, 17

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders

    Palmqvist, S., Janelidze, S., Quiroz, Y. T., Zetterberg, H., Lopera, F., Stomrud, E., Su, Y., Chen, Y., Serrano, G. E., Leuzy, A., Mattsson-Carlgren, N., Strandberg, O., Smith, R., Villegas, A., Sepulveda-Falla, D., Chai, X., Proctor, N. K., Beach, T. G., Blennow, K., Dage, J. L., Reiman, E. M. & Hansson, O., 25.08.2020, In: JAMA-J AM MED ASSOC. 324, 8, p. 772-781 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Common disbalance in the brain parenchyma of dementias: Phospholipid profile analysis between CADASIL and sporadic Alzheimer's disease

    Sabogal-Guáqueta, A. M., Arias-Londoño, J. D., Gutierrez-Vargas, J., Sepulveda-Falla, D., Glatzel, M., Villegas-Lanau, A. & Cardona-Gómez, G. P., 01.08.2020, In: BBA-MOL BASIS DIS. 1866, 8, p. 165797

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Decreased Deposition of Beta-Amyloid 1-38 and Increased Deposition of Beta-Amyloid 1-42 in Brain Tissue of Presenilin-1 E280A Familial Alzheimer's Disease Patients

    Dinkel, F., Trujillo-Rodriguez, D., Villegas, A., Streffer, J., Mercken, M., Lopera, F., Glatzel, M. & Sepulveda-Falla, D., 28.07.2020, In: FRONT AGING NEUROSCI. 12, p. 220

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study

    Quiroz, Y. T., Zetterberg, H., Reiman, E. M., Chen, Y., Su, Y., Fox-Fuller, J. T., Garcia, G., Villegas, A., Sepulveda-Falla, D., Villada, M., Arboleda-Velasquez, J. F., Guzmán-Vélez, E., Vila-Castelar, C., Gordon, B. A., Schultz, S. A., Protas, H. D., Ghisays, V., Giraldo, M., Tirado, V., Baena, A., Munoz, C., Rios-Romenets, S., Tariot, P. N., Blennow, K. & Lopera, F., 06.2020, In: LANCET NEUROL. 19, 6, p. 513-521 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Susceptibility to cellular stress in PS1 mutant N2a cells is associated with mitochondrial defects and altered calcium homeostasis

    Rojas-Charry, L., Calero-Martinez, S., Morganti, C., Morciano, G., Park, K., Hagel, C., Marciniak, S. J., Glatzel, M., Pinton, P. & Sepulveda-Falla, D., 15.04.2020, In: SCI REP-UK. 10, 1, p. 6455

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Deficits in developmental neurogenesis and dendritic spine maturation in mice lacking the serine protease inhibitor neuroserpin

    Hermann, M., Reumann, R., Schostak, K., Kement, D., Gelderblom, M., Bernreuther, C., Frischknecht, R., Schipanski, A., Marik, S., Krasemann, S., Sepulveda-Falla, D., Schweizer, M., Magnus, T., Glatzel, M. & Galliciotti, G., 01.2020, In: MOL CELL NEUROSCI. 102, p. 103420

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. 2019

  37. Complement 3+-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia

    Hartmann, K., Sepulveda-Falla, D., Rose, I. V. L., Madore, C., Muth, C., Matschke, J., Butovsky, O., Liddelow, S., Glatzel, M. & Krasemann, S., 22.05.2019, In: ACTA NEUROPATHOL COM. 7, 1, p. 83

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Neural Plasticity during Aging

    Arcos-Burgos, M., Lopera, F., Sepulveda-Falla, D. & Mastronardi, C., 26.03.2019, In: NEURAL PLAST. 2019, p. 6042132

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  39. The Colombian-German network for neurodegenerative research: UndoAD

    Sepulveda-Falla, D., Villegas, A., Lopera, F. & Glatzel, M., 01.2019, In: LANCET NEUROL. 18, 1, p. 29

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  40. Phagocytosis of Apoptotic Cells Is Specifically Upregulated in ApoE4 Expressing Microglia in vitro

    Muth, C., Hartmann, A., Sepulveda-Falla, D., Glatzel, M. & Krasemann, S., 2019, In: FRONT CELL NEUROSCI. 13, p. 181

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. 2018

  42. Distinct microglia profile in Creutzfeldt-Jakob disease and Alzheimer's disease is independent of disease kinetics

    Krbot, K., Hermann, P., Skorić, M. K., Zerr, I., Sepulveda-Falla, D., Goebel, S., Matschke, J., Krasemann, S. & Glatzel, M., 12.2018, In: NEUROPATHOLOGY. 38, 6, p. 591-600 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. 2017

  44. Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease

    Rasmussen, J., Mahler, J., Beschorner, N., Kaeser, S. A., Häsler, L. M., Baumann, F., Nyström, S., Portelius, E., Blennow, K., Lashley, T., Fox, N. C., Sepulveda-Falla, D., Glatzel, M., Oblak, A. L., Ghetti, B., Nilsson, K. P. R., Hammarström, P., Staufenbiel, M., Walker, L. C. & Jucker, M., 05.12.2017, In: P NATL ACAD SCI USA. 114, 49, p. 13018-13023 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Losing sleep over mitochondria: A new player in the pathophysiology of Fatal Familial Insomnia

    Glatzel, M. & Sepulveda-Falla, D., 01.2017, In: BRAIN PATHOL. 27, 1, p. 107-108

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  46. 2016

  47. Mutations modifying sporadic Alzheimer's disease age of onset

    Vélez, J. I., Lopera, F., Patel, H. R., Johar, A. S., Cai, Y., Rivera, D., Tobón, C., Villegas, A., Sepulveda-Falla, D., Lehmann, S. G., Easteal, S., Mastronardi, C. A. & Arcos-Burgos, M., 12.2016, In: AM J MED GENET B. 171, 8, p. 1116-1130 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Amyloid-β Precursor Protein Modulates the Sorting of Testican-1 and Contributes to Its Accumulation in Brain Tissue and Cerebrospinal Fluid from Patients with Alzheimer Disease

    Barrera-Ocampo, A., Arlt, S., Matschke, J., Hartmann, U., Puig Martorell, B., Ferrer, I., Zürbig, P., Glatzel, M., Sepulveda-Falla, D. & Jahn, H., 02.08.2016, In: J NEUROPATH EXP NEUR. 75, 9, p. 903-916

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease

    Vélez, J. I., Lopera, F., Sepulveda-Falla, D., Patel, H. R., Johar, A. S., Chuah, A., Tobón, C., Rivera, D., Villegas, A., Cai, Y., Peng, K., Arkell, R., Castellanos, F. X., Andrews, S. J., Silva Lara, M. F., Creagh, P. K., Easteal, S., de Leon, J., Wong, M. L., Licinio, J., Mastronardi, C. A. & Arcos-Burgos, M., 01.07.2016, In: MOL PSYCHIATR. 21, 7, p. 916-24

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma

    Friedrich, C., von Bueren, A. O., Kolevatova, L., Bernreuther, C., Grob, T., Sepulveda-Falla, D., van den Boom, L., Westphal, M., Simon, R. & Glatzel, M., 02.2016, In: CHILD NERV SYST. 32, 2, p. 281-90

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. 2015

  52. Qualitative changes in human γ-secretase underlie familial Alzheimer's disease

    Szaruga, M., Veugelen, S., Benurwar, M., Lismont, S., Sepulveda-Falla, D., Lleo, A., Ryan, N. S., Lashley, T., Fox, N. C., Murayama, S., Gijsen, H., De Strooper, B. & Chávez-Gutiérrez, L., 19.10.2015, In: J EXP MED. 212, 12, p. 2003-2013

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. 2014

  54. Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis

    Sepulveda-Falla, D., Barrera-Ocampo, A. A., Hagel, C., Korwitz, A., Vinueza-Veloz, M. F., Zhou, K., Schonewille, M., Zhou, H., Velazquez-Perez, L., Rodriguez-Labrada, R., Villegas, A., Ferrer, I., Lopera, F., Langer, T., De Zeeuw, C. I. & Glatzel, M., 01.04.2014, In: J CLIN INVEST. 124, 4, p. 1552-67 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  55. High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease

    Dohler, F., Sepulveda-Falla, D., Krasemann, S., Altmeppen, H., Schlüter, H., Hildebrand, D., Zerr, I., Matschke, J. & Glatzel, M., 01.03.2014, In: BRAIN. 137, Pt 3, p. 873-86 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  56. Immune activation in amyloid-β-related angiitis correlates with decreased parenchymal amyloid-β plaque load

    Bogner, S., Bernreuther, C., Matschke, J., Barrera-Ocampo, A. A., Sepulveda-Falla, D., Leypoldt, F., Magnus, T., Haag, F., Bergmann, M., Brück, W., Vogelgesang, S. & Glatzel, M., 01.01.2014, In: NEURODEGENER DIS. 13, 1, p. 38-44 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  57. 2013

  58. Specific de-SUMOylation triggered by acquisition of spatial learning is related to epigenetic changes in the rat hippocampus

    Castro Gomez, M. S., Barrera-Ocampo, A. A., Machado-Rodriguez, G., Castro-Alvarez, J. F., Glatzel, M., Giraldo, M. & Sepulveda-Falla, D., 04.12.2013, In: NEUROREPORT. 24, 17, p. 976-81 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  59. Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease.

    Pera, M., Alcolea, D., Sánchez-Valle, R., Guardia-Laguarta, C., Colom-Cadena, M., Badiola, N., Suárez-Calvet, M., Lladó, A., Barrera-Ocampo, A. A., Sepulveda-Falla, D., Blesa, R., Molinuevo, J. L., Clarimón, J., Ferrer, I., Gelpi, E. & Lleó, A., 2013, In: ACTA NEUROPATHOL. 125, 2, p. 201-213 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  60. 2012

  61. Phenotypic profile of early-onset familial Alzheimer's disease caused by presenilin-1 E280A mutation.

    Sepulveda-Falla, D., Glatzel, M. & Lopera, F., 2012, In: J ALZHEIMERS DIS. 32, 1, p. 1-12 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  62. 2011

  63. Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease.

    Sepulveda-Falla, D., Matschke, J., Bernreuther, C., Hagel, C., Puig Martorell, B., Villegas, A., Garcia, G., Zea, J., Gomez-Mancilla, B., Ferrer, I., Lopera, F. & Glatzel, M., 2011, In: BRAIN PATHOL. 21, 4, p. 452-463 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  64. Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study.

    Acosta-Baena, N., Sepulveda-Falla, D., Lopera-Gómez, C. M., Jaramillo-Elorza, M. C., Moreno, S., Aguirre-Acevedo, D. C., Saldarriaga, A. & Lopera, F., 2011, In: LANCET NEUROL. 10, 3, p. 213-220 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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