Department of Stem Cell Transplantation
Publications
- 2009
JAK2-V617F-triggered preemptive and salvage adoptive immunotherapy with donor-lymphocyte infusion in patients with myelofibrosis after allogeneic stem cell transplantation.
Kröger, N., Alchalby, H., Klyuchnikov, E., Badbaran, A., Hildebrandt, Y., Ayuketang Ayuk, F., Bacher, U., Bock, O., Kvasnicka, M., Fehse, B. & Zander, A. R., 2009, In: BLOOD. 113, 8, p. 1866-1868 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lenalidomide as salvage therapy after allo-SCT for multiple myeloma is effective and leads to an increase of activated NK (NKp44(+)) and T (HLA-DR(+)) cells.
Lioznov, M., El-Cheikh, J., Hoffmann, F., Hildebrandt, Y., Ayuketang Ayuk, F., Wolschke, C., Atanackovic, D., Schilling, G., Badbaran, A., Bacher, U., Fehse, B., Zander, A. R., Blaise, D., Mohty, M. & Kröger, N., 2009, In: BONE MARROW TRANSPL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis.
Riecken, K., Mock, U., Petrowitz, B., Bartsch, U. & Fehse, B., 2009, In: GENE THER.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Longitudinal analysis and prognostic effect of cancer-testis antigen expression in multiple myeloma.
Atanackovic, D., Luetkens, T., Hildebrandt, Y., Arfsten, J., Bartels, K., Horn, C., Stahl, T., Cao, Y., Zander, A. R., Bokemeyer, C. & Kröger, N., 2009, In: CLIN CANCER RES. 15, 4, p. 1343-1352 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular determinants of prognosis in acute myeloid leukemia (AML) with normal karyotype.
Bacher, U. & Haferlach, C., 2009, In: LEUKEMIA LYMPHOMA. 50, 9, p. 1403-1405 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular diagnostics in acute leukemias.
Bacher, U., Schnittger, S., Haferlach, C. & Haferlach, T., 2009, In: CLIN CHEM LAB MED. 47, 11, p. 1333-1341 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Outcome after allogeneic transplantation for adult acute myeloid leukemia patients exhibiting isolated or associated trisomy 8 chromosomal abnormality: a survey on behalf of the ALWP of the EBMT.
Chevallier, P., Labopin, M., Nagler, A., Ljungman, P., Verdonck, L. F., Volin, L., Zander, A. R., Finke, J., Socie, G., Cordonnier, C., Harousseau, J-L., Mohty, M. & Rocha, V., 2009, In: BONE MARROW TRANSPL. 44, 9, p. 589-594 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Outcome of allo-SCT for chronic myelomonocytic leukemia.
Ocheni, S., Kröger, N., Zabelina, T., Zander, A. R. & Bacher, U., 2009, In: BONE MARROW TRANSPL. 43, 8, p. 659-661 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Outcome of transplantation for myelofibrosis.
Ballen, K. K., Shrestha, S., Sobocinski, K. A., Zhang, M-J., Bashey, A., Bolwell, B. J., Cervantes, F., Devine, S. M., Gale, R. P., Gupta, V., Hahn, T. E., Hogan, W. J., Kröger, N., Litzow, M. R., Marks, D. I., Maziarz, R. T., McCarthy, P. L., Schiller, G., Harry, C. S., Roy, V., Wiernik, P. H., Horowitz, M. M., Giralt, S. A. & Arora, M., 2009, In: BIOL BLOOD MARROW TR. *16*, 3, p. 358-367 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pegfilgrastim compared to lenograstim after allogeneic peripheral blood stem-cell transplantation from unrelated donors.
Ocheni, S., Zabelina, T., Bacher, U., Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 2009, In: LEUKEMIA LYMPHOMA. 50, 4, p. 612-618 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Percutaneous intramyocardial stem cell injection in patients with acute myocardial infarction: first-in-man study.
Krause, K., Jaquet, K., Schneider, C., Haupt, S., Lioznov, M., Otte, K-M. & Kuck, K-H., 2009, In: HEART. 95, 14, p. 1145-1152 14.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Perspectives of gene expression profiling for diagnosis and therapy in haematological malignancies.
Bacher, U., Kohlmann, A. & Haferlach, T., 2009, In: Brief Funct Genomic Proteomic. 8, 3, p. 184-193 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Post-transplant immunotherapy with donor-lymphocyte infusion and novel agents to upgrade partial into complete and molecular remission in allografted patients with multiple myeloma.
Kröger, N., Badbaran, A., Lioznov, M., Schwartz, S., Zeschke, S., Hildebrandt, Y., Ayuketang Ayuk, F., Atanackovic, D., Schilling, G., Zabelina, T., Bacher, U., Klyuchnikov, E., Shimoni, A., Nagler, A., Corradini, P., Fehse, B. & Zander, A. R., 2009, In: EXP HEMATOL. 37, 7, p. 791-798 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative monitoring of NPM1 mutations provides a valid minimal residual disease parameter following allogeneic stem cell transplantation.
Bacher, U., Badbaran, A., Fehse, B., Zabelina, T., Zander, A. R. & Kröger, N., 2009, In: EXP HEMATOL. 37, 1, p. 135-142 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduced proliferation of CD34(+) cells from patients with acute myeloid leukemia after gene transfer of INPP5D.
Metzner, A., Precht, C., Fehse, B., Fiedler, W., Stocking, C., Günther, A., Mayr, G. W. & Jücker, M., 2009, In: GENE THER. 16, 4, p. 570-573 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral insertion site analysis in dominant haematopoietic clones.
Kustikova, O. S., Modlich, U. & Fehse, B., 2009, In: Methods Mol Biol. 506, p. 373-390Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.
Michaelis, M., Rothweiler, F., Klassert, D., von Deimling, A., Riecken, K., Fehse, B., Kammerer, B., Doerr, H. W. & Cinatl, J., 2009, In: CANCER RES. 69, 2, p. 416-421 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Risk factors for therapy-related myelodysplastic syndrome and acute myeloid leukemia treated with allogeneic stem cell transplantation.
Kröger, N., Brand, R., van Biezen, A., Zander, A. R., Dierlamm, J., Niederwieser, D., Devergie, A., Ruutu, T., Cornish, J., Ljungman, P., Gratwohl, A., Cordonnier, C., Beelen, D., Deconinck, E., Symeonidis, A. & de Witte, T., 2009, In: HAEMATOLOGICA. 94, 4, p. 542-549 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RQ-PCR based WT1 expression in comparison to BCR-ABL quantification can predict Philadelphia negative clonal evolution in patients with imatinib-treated chronic myeloid leukaemia.
Schnittger, S., Bacher, U., Kern, W., Tschulik, C., Weiss, T., Haferlach, C. & Haferlach, T., 2009, In: BRIT J HAEMATOL. 146, 6, p. 665-668 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Safety of conditioning agents for allogeneic haematopoietic transplantation.
Bacher, U., Klyuchnikov, E., Wiedemann, B., Kröger, N. & Zander, A. R., 2009, In: EXPERT OPIN DRUG SAF. 8, 3, p. 305-315 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Second allogeneic stem cell transplantation in myeloid malignancies.
Hartwig, M., Ocheni, S., Asenova, S., Wiedemann, B., Zabelina, T., Ayuketang Ayuk, F., Kabisch, H., Erttmann, R., Kröger, N., Zander, A. R. & Bacher, U., 2009, In: ACTA HAEMATOL-BASEL. 122, 4, p. 185-192 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Second-generation tyrosine kinase inhibitors in the post-transplant period in patients with chronic myeloid leukemia or Philadelphia-positive acute lymphoblastic leukemia.
Klyuchnikov, E., Schafhausen, P., Kröger, N., Brümmendorf, T., Osanmaz, O., Asenova, S., Zabelina, T., Ocheni, S., Ayuketang Ayuk, F., Zander, A. R. & Bacher, U., 2009, In: ACTA HAEMATOL-BASEL. 122, 1, p. 6-10 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sensitising leukemic cells by targeting microenvironment.
Klyuchnikov, E. & Kröger, N., 2009, In: LEUKEMIA LYMPHOMA. 50, 3, p. 319-320 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Severe aplastic anaemia following leflunomide therapy.
Wüsthof, M., Smirnova, A., Bacher, U., Kröger, N., Zander, A. R., Schuch, G. & Bokemeyer, C., 2009, In: RHEUMATOLOGY.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Similar patterns of chromosome abnormalities in CML occur in addition to the Philadelphia chromosome with or without tyrosine kinase inhibitor treatment.
Haferlach, C., Bacher, U., Schnittger, S., Weiss, T., Kern, W. & Haferlach, T., 2009, In: LEUKEMIA.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sleep disturbances and emotional distress in the acute course of hematopoietic stem cell transplantation.
Rischer, J., Scherwath, A., Zander, A. R., Koch, U. & Schulz-Kindermann, F., 2009, In: BONE MARROW TRANSPL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Standard graft-versus-host disease prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: a randomised, open-label, multicentre phase 3 trial.
Finke, J., Bethge, W. A., Schmoor, C., Ottinger, H. D., Stelljes, M., Zander, A. R., Volin, L., Ruutu, T., Heim, D. A., Schwerdtfeger, R., Kolbe, K., Mayer, J., Maertens, J. A., Linkesch, W., Holler, E., Koza, V., Bornhäuser, M., Einsele, H., Kolb, H-J., Bertz, H., Egger, M., Grishina, O. & Socié, G., 2009, In: LANCET ONCOL. 10, 9, p. 855-864 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stehen kognitive Funktionen im Zusammenhang mit Angst, Depression und Posttraumatischer Belastungsstörung bei Brustkrebspatientinnen nach onkologischer Behandlung?
Schirmer, L., Mehnert, A., Scherwath, A., Schleimer, B., Schulz-Kindermann, F., Zander, A. R. & Koch-Gromus, U., 2009, In: Z PSYCHIATR PSYCH PS. 57, 1, p. 33-42 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stem cell marking with promotor-deprived self-inactivating retroviral vectors does not lead to induced clonal imbalance.
Cornils, K., Lange, C., Schambach, A., Brugman, M. H., Nowak, R., Lioznov, M., Baum, C. & Fehse, B., 2009, In: MOL THER. 17, 1, p. 131-143 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Successful unrelated donor stem cell transplantation for advanced myelofibrosis in an adult patient with history of orthotopic liver transplantation.
Perz, J. B., Hegenbart, U., Kröger, N., Otto, G., Ho, A. D. & Dreger, P., 2009, In: HAEMATOLOGICA. 94, 4, p. 594-596 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Syngenic graft-versus-chronic-myeloid-leukemia-effect?
Ocheni, S., Schafhausen, P., Bacher, U., Fehse, B. & Kröger, N., 2009, In: CTT-Cell Ther Transpl. 1, 3, p. 66-68 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The changing scene of allogeneic stem cell transplantation for chronic myeloid leukemia-a report from the German Registry covering the period from 1998 to 2004.
Bacher, U., Klyuchnikov, E., Zabelina, T., Ottinger, H., Beelen, D., Schrezenmeier, H., Ehninger, G., Müller, C., Berger, J., Suttorp, M., Kolb, H-J., Kröger, N. & Zander, A. R., 2009, In: ANN HEMATOL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The impact of cytomorphology, cytogenetics, molecular genetics, and immunophenotyping in a comprehensive diagnostic workup of myelodysplastic syndromes.
Bacher, U., Haferlach, T., Kern, W., Weiss, T., Schnittger, S. & Haferlach, C., 2009, In: CANCER-AM CANCER SOC. 115, 19, p. 4524-4532 19.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Toward MSC in solid organ transplantation: 2008 position paper of the MISOT study group.
Dahlke, M. H., Hoogduijn, M., Eggenhofer, E., Popp, F. C., Renner, P., Slowik, P., Rosenauer, A., Piso, P., Geissler, E. K., Lange, C., Chabannes, D., Mazzanti, B., Bigenzahn, S., Bertolino, P., Kunter, U., Introna, M., Alessandro, R., Capelli, C., Perico, N., Casiraghi, F., Noris, M., Gotti, E., Seifert, M., Riccardo, S., Verspaget, H. W., van Hoek, B., Bartholomew, A., Wekerle, T., Volk, H. D., Remuzzi, G., Deans, R., Lazarus, H., Schlitt, H. J. & Baan, C. C., 2009, In: TRANSPLANTATION. 88, 5, p. 614-619 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Unrelated donor stem cell transplantation in acquired severe aplastic anemia: a systematic review.
Peinemann, F., Grouven, U., Kröger, N., Pittler, M., Zschorlich, B. & Lange, S., 2009, In: HAEMATOLOGICA. 94, 12, p. 1732-1742 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Initial report on a phase I clinical trial: Prevention and treatment of post-operative Acute Kidney Injury with allogeneic Mesenchymal Stem Cells in patients who require on-pump cardiac surgery.
Gooch, A., Doty, J., Flores, J., Toegel, FE., Reiss, GR., Lange, C., Zander, AR., Zhang, P. & Westenfelder, C., 24.12.2008Research output: Other contribution › Net-publication - Articles in scientific forums or blogs › Research › peer-review
Analysis of sternotomy as treatment option for the resection of bilateral pulmonary metastases in pediatric solid tumors
Fuchs, J., Seitz, G., Ellerkamp, V., Dietz, K., Bosk, A., Müller, I., Warmann, S. W. & Schäfer, J. F., 12.2008, In: J SURG ONCOL. 17, 4, p. 323-30 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mesenchymal stem cell therapy for degenerative inflammatory disorders
Müller, I., Lymperi, S. & Dazzi, F., 12.2008, In: CURR OPIN ORGAN TRAN. 13, 6, p. 639-44 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Secretion of angiogenic proteins by human multipotent mesenchymal stromal cells and their clinical potential in the treatment of avascular osteonecrosis
Müller, I., Vaegler, M., Holzwarth, C., Tzaribatchev, N., Pfister, S. M., Schütt, B., Reize, P., Greil, J., Handgretinger, R. & Rudert, M., 11.2008, In: LEUKEMIA. 22, 11, p. 2054-61 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Akt as a therapeutic target in cancer
Steelman, L. S., Stadelman, K. M., Chappell, W. H., Horn, S., Bäsecke, J., Cervello, M., Nicoletti, F., Libra, M., Stivala, F., Martelli, A. M. & McCubrey, J. A., 01.09.2008, In: EXPERT OPIN THER TAR. 12, 9, p. 1139-65 27 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
WT1 protein expression in slowly proliferating myeloid leukemic cell lines is scarce throughout the cell cycle with a minimum in G0/G1 phase
Kerst, G., Bergold, N., Viebahn, S., Gieseke, F., Kalinova, M., Trka, J., Handgretinger, R. & Müller, I., 09.2008, In: Leukemia research. 32, 9, p. 1393-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
WT1 protein expression in childhood acute leukemia
Kerst, G., Bergold, N., Gieseke, F., Coustan-Smith, E., Lang, P., Kalinova, M., Handgretinger, R., Trka, J. & Müller, I., 05.2008, In: AM J HEMATOL. 83, 5, p. 382-6 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mesenchymal stromal cells: a novel treatment option for steroid-induced avascular osteonecrosis
Tzaribachev, N., Vaegler, M., Schaefer, J., Reize, P., Rudert, M., Handgretinger, R. & Müller, I., 03.2008, In: CAN MED ASSOC J. 10, 3, p. 232-4 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficient in vitro generation of adult multipotent cells from mobilized peripheral blood CD133+ cells
Kuçi, S., Kuçi, Z., Schmid, S., Seitz, G., Müller, I., Dufke, A., Leimig, T., Murti, G., Jurecic, R., Schumm, M., Lang, P., Bruchelt, G., Bader, P., Klingebiel, T., Niethammer, D. & Handgretinger, R., 02.2008, In: CELL PROLIFERAT. 41, 1, p. 12-27 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy
McCubrey, J. A., Sokolosky, M. L., Lehmann, B. D., Taylor, J. R., Navolanic, P. M., Chappell, W. H., Abrams, S. L., Stadelman, K. M., Wong, E. W. T., Misaghian, N., Horn, S., Bäsecke, J., Libra, M., Stivala, F., Ligresti, G., Tafuri, A., Milella, M., Zarzycki, M., Dzugaj, A., Chiarini, F., Evangelisti, C., Martelli, A. M., Terrian, D. M., Franklin, R. A. & Steelman, L. S., 01.01.2008, In: Advances in enzyme regulation. 48, p. 113-35 23 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Abnormal expression of only the CD34 part of a transgenic CD34/herpes simplex virus-thymidine kinase fusion protein is associated with ganciclovir resistance.
Bennour, E., Ferrand, C., Rémy-Martin, J-P., Certoux, J-M., Gorke, S., Qasim, W., Gaspar, H. B., Baumert, T., Duperrier, A., Deschamps, M., Fehse, B., Tiberghien, P. & Robinet, E., 2008, In: HUM GENE THER. 19, 7, p. 699-709 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic stem cell transplantation in acute myeloid leukemia: establishment of indications on the basis of individual risk stratification.
Zander, A. R., Bacher, U. & Finke, J., 2008, In: DTSCH ARZTEBL INT. 105, 39, p. 663-669 39.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis
Weber, K., Bartsch, U., Stocking, C. & Fehse, B., 2008, In: MOL THER. 16, 4, p. 698-706 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A new case with rare e6a2 BCR-ABL fusion transcript developing two new resistance mutations during imatinib mesylate, which were replaced by T315I after subsequent dasatinib treatment.
Schnittger, S., Bacher, U., Kern, W., Haferlach, T., Hertenstein, B. & Haferlach, C., 2008, In: LEUKEMIA. 22, 4, p. 856-858 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Anti-thymocyte globulin overcomes the negative impact of HLA mismatching in transplantation from unrelated donors.
Ayuketang Ayuk, F., Diyachenko, G., Zabelina, T., Panse, J., Wolschke, C., Eiermann, T., Binder, T., Fehse, B., Erttmann, R., Kabisch, H., Bacher, U., Kröger, N. & Zander, A. R., 2008, In: EXP HEMATOL. 36, 8, p. 1047-1054 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review