Department of Stem Cell Transplantation
Publications
- 2012
Development and validation of a real-time quantification assay to detect and monitor BRAFV600E mutations in hairy cell leukemia.
Schnittger, S., Bacher, U., Haferlach, T., Wendland, N., Ulke, M., Dicker, F., Grossmann, V., Haferlach, C. & Kern, W., 2012, In: BLOOD. 119, 13, p. 3151-3154 13.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diagnostic performance of whole-body MRI for the detection of persistent or relapsing disease in multiple myeloma after stem cell transplantation.
Bannas, P., Hentschel, H. B., Bley, T., Treszl, A., Zu Eulenburg, C. G., Derlin, T., Yamamura, J., Adam, G., Stübig, T., Kröger, N. & Weber, C., 2012, In: EUR RADIOL. 22, 9, p. 2007-2012 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Diagnostics of acute leukemias: interaction of phenotypic and genetic methods].
Bacher, U., Haferlach, C., Schnittger, S., Kern, W., Ott, M. M. & Haferlach, T., 2012, In: PATHOLOGE. 33, 6, p. 528-538 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Discovered on gastrointestinal stromal tumour 1 (DOG1): a useful immunohistochemical marker for diagnosing chondroblastoma.
Akpalo, H., Lange, C. & Zustin, J., 2012, In: HISTOPATHOLOGY. 60, 7, p. 1099-1106 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diversity of the juxtamembrane and TKD1 mutations (exons 13-15) in the FLT3 gene with regards to mutant load, sequence, length, localization, and correlation with biological data.
Schnittger, S., Bacher, U., Haferlach, C., Alpermann, T., Kern, W. & Haferlach, T., 2012, In: GENE CHROMOSOME CANC. 51, 10, p. 910-924 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Donor lymphocyte infusions and second transplantation as salvage treatment for relapsed myelofibrosis after reduced-intensity allografting.
Klyuchnikov, E., Holler, E., Bornhäuser, M., Kobbe, G., Nagler, A., Shimoni, A., Könecke, C., Wolschke, C., Bacher, U., Zander, A. R. & Kröger, N., 2012, In: BRIT J HAEMATOL. 159, 2, p. 172-181 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficient lentiviral transduction and transgene expression in primary human B cells.
Mock, U., Thiele, R., Uhde, A., Fehse, B. & Horn, S., 2012, In: HUM GENE THER METHOD. 23, 6, p. 408-415 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ETV6 rearrangements are recurrent in myeloid malignancies and are frequently associated with other genetic events.
Haferlach, C., Bacher, U., Schnittger, S., Alpermann, T., Zenger, M., Kern, W. & Haferlach, T., 2012, In: GENE CHROMOSOME CANC. 51, 4, p. 328-337 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
European data on stem cell mobilization with plerixafor in non-Hodgkin's lymphoma, Hodgkin's lymphoma and multiple myeloma patients. A subgroup analysis of the European Consortium of stem cell mobilization.
Hübel, K., Fresen, M. M., Apperley, J. F., Basak, G. W., Douglas, K. W., Gabriel, I. H., Geraldes, C., Jaksic, O., Koristek, Z., Kröger, N., Lanza, F., Lemoli, R. M., Mikala, G., Selleslag, D., Worel, N., Mohty, M. & Duarte, R. F., 2012, In: BONE MARROW TRANSPL. 47, 8, p. 1046-1050 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of CEBPA is reduced in RUNX1-mutated acute myeloid leukemia.
Grossmann, V., Bacher, U., Kohlmann, A., Butschalowski, K., Roller, A., Jeromin, S., Dicker, F., Kern, W., Schnittger, S., Haferlach, T. & Haferlach, C., 2012, In: BLOOD CANCER J. 2, p. 86Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
Preukschas, M., Hagel, C., Schulte, A., Riecken, K., Lamszus, K., Sievert, H., Pällmann, N., Bokemeyer, C., Hauber, J., Balabanov, M. & Balabanov, S., 2012, In: PLOS ONE. 7, 8, p. 43468 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
EZH2 mutations and their association with PICALM-MLLT10 positive acute leukaemia.
Grossmann, V., Bacher, U., Kohlmann, A., Artusi, V., Klein, H-U., Dugas, M., Schnittger, S., Alpermann, T., Kern, W., Haferlach, T. & Haferlach, C., 2012, In: BRIT J HAEMATOL. 157, 3, p. 387-390 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Frequency and prognostic impact of the aberrant CD8 expression in 5,523 patients with chronic lymphocytic leukemia.
Kern, W., Bacher, U., Haferlach, C., Alpermann, T., Dicker, F., Schnittger, S. & Haferlach, T., 2012, In: CYTOM PART B-CLIN CY. 82, 3, p. 145-150 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of genetic parameters associated with disease progression in plasma cell myeloma.
Bacher, U. & Binder, M., 2012, In: LEUKEMIA RES. 36, 1, p. 23-24 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunotherapy for multiple myeloma.
Kröger, N., Mohty, M., Nagler, A. & Yi, Q., 2012, In: Clin Dev Immunol. 2012, p. 797165Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of the NK cell receptor LIR-1 (ILT-2/CD85j/LILRB1) on cytotoxicity against multiple myeloma.
Heidenreich, S., Zu Eulenburg, C. G., Hildebrandt, Y., Stübig, T., Sierich, H., Badbaran, A., Eiermann, T., Binder, T. & Kröger, N., 2012, In: Clin Dev Immunol. 2012, p. 652130Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Longitudinal analysis of tetanus- and influenza-specific IgG antibodies in myeloma patients.
Kobold, S., Luetkens, T., Bartels, B. M., Cao, Y., Hildebrandt, Y., Sezer, O., Reinhard, H., Templin, J., Bartels, K., Lajmi, N., Haag, F., Bokemeyer, C., Kröger, N. & Atanackovic, D., 2012, In: Clin Dev Immunol. 2012, p. 134081Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular analyses of 15,542 patients with suspected BCR-ABL1-negative myeloproliferative disorders allow to develop a stepwise diagnostic workflow.
Schnittger, S., Bacher, U., Eder, C., Dicker, F., Alpermann, T., Grossmann, V., Kohlmann, A., Kern, W., Haferlach, C. & Haferlach, T., 2012, In: HAEMATOLOGICA. 97, 10, p. 1582-1585 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular analysis of RAS-RAF tyrosine-kinase signaling pathway alterations in patients with plasma cell myeloma.
Grossmann, V., Bacher, U., Artusi, V., Kohlmann, A., Nadarajah, N., Kern, W., Schnittger, S., Haferlach, T. & Haferlach, C., 2012, In: BLOOD CANCER J. 2, p. 85Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monitoring and prevention of relapse after allogeneic hematopoietic cell transplantation for myeloid malignancies.
Bacher, U., Talano, J-A. & Bishop, M. R., 2012, In: BIOL BLOOD MARROW TR. 18, 1 Suppl, p. 62-73 1 Suppl.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monoclonal B-cell lymphocytosis is closely related to chronic lymphocytic leukaemia and may be better classified as early-stage CLL.
Kern, W., Bacher, U., Haferlach, C., Dicker, F., Alpermann, T., Schnittger, S. & Haferlach, T., 2012, In: BRIT J HAEMATOL. 157, 1, p. 86-96 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multilineage dysplasia does not influence prognosis in CEBPA-mutated AML, supporting the WHO proposal to classify these patients as a unique entity.
Bacher, U., Schnittger, S., Macijewski, K., Grossmann, V., Kohlmann, A., Alpermann, T., Kowarsch, A., Nadarajah, N., Kern, W., Haferlach, C. & Haferlach, T., 2012, In: BLOOD. 119, 20, p. 4719-4722 20.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation: diagnostic and therapeutic challenges.
Shah, N. N., Bacher, U., Fry, T., Calvo, K. R., Stetler-Stevenson, M., Arthur, D. C., Kurlander, R., Baird, K., Wise, B., Giralt, S., Bishop, M., Hardy, N. M. & Wayne, A. S., 2012, In: AM J HEMATOL. 87, 9, p. 916-922 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts.
Schulze, J., Riecken, K., Baranowsky, A., Streichert, T., Lange, T., Spiro, A. S., Albers, J., Seitz, S., Zustin, J., Amling, M., Fehse, B. & Schinke, T., 2012, In: CANCER LETT. 317, 1, p. 106-113 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Platelet lysate suppresses the expression of lipocalin-type prostaglandin D2 synthase that positively controls adipogenic differentiation of human mesenchymal stromal cells.
Lange, C., Brunswig-Spickenheier, B., Eissing, L. & Scheja, L., 2012, In: EXP CELL RES. 318, 18, p. 2284-2296 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Plerixafor for autologous peripheral blood stem cell mobilization in patients previously treated with fludarabine or lenalidomide.
Malard, F., Kröger, N., Gabriel, I. H., Hübel, K., Apperley, J. F., Basak, G. W., Douglas, K. W., Geraldes, C., Jaksic, O., Koristek, Z., Lanza, F., Lemoli, R., Mikala, G., Selleslag, D., Worel, N., Mohty, M. & Duarte, R. F., 2012, In: BIOL BLOOD MARROW TR. 18, 2, p. 314-317 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prognoses of MDS subtypes RARS, RCMD and RCMD-RS are comparable but cytogenetics separates a subgroup with inferior clinical course.
Bacher, U., Kern, W., Alpermann, T., Schnittger, S., Haferlach, C. & Haferlach, T., 2012, In: LEUKEMIA RES. 36, 7, p. 826-831 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Replacement of hematopoietic system by allogeneic stem cell transplantation in myelofibrosis patients induces rapid regression of bone marrow fibrosis.
Kröger, N., Kvasnicka, M. & Thiele, J., 2012, In: Fibrogenesis Tissue Repair. 5 Suppl 1, p. 25Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking : Vielfarbige Zellmarkierung zur klonalen Analyse
Riecken, K., Thomaschewski, M., Warlich, M., Cornils, K., Benten, D. & Fehse, B., 2012, In: Laborwelt. 13, 1, p. 7-9 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking with lentiviral vectors for multicolor clonal cell tracking.
Riecken, K., Thomaschewski, M., Benten, D. & Fehse, B., 2012, In: NAT PHYS. 7, 5, p. 839-849 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Risk models predicting survival after reduced-intensity transplantation for myelofibrosis.
Alchalby, H., Yunus, D-R., Zabelina, T., Kobbe, G., Holler, E., Bornhäuser, M., Schwerdtfeger, R., Bethge, W., Kvasnicka, H. M., Büsche, G., Ayuketang Ayuk, F., Bacher, U., Zander, A. R. & Kröger, N., 2012, In: BRIT J HAEMATOL. 157, 1, p. 75-85 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of interleukin 16 in multiple myeloma.
Atanackovic, D., Hildebrandt, Y., Templin, J., Cao, Y., Keller, C., Panse, J., Meyer, S., Reinhard, H., Bartels, K., Lajmi, N., Sezer, O., Zander, A. R., Marx, A., Uhlig, R., Zustin, J., Bokemeyer, C. & Kröger, N., 2012, In: JNCI-J NATL CANCER I. 104, 13, p. 1005-1020 13.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Screening of Potential HIV-1 Inhibitors/Replication Blockers Using Secure Lentiviral in Vitro System.
Prokofjeva, M. M., Spirin, P. V., Yanvarev, D. V., Ivanov, A. V., Novikov, M. S., Stepanov, O. A., Gottikh, M. B., Kochetkov, S. N., Fehse, B., Stocking, C. & Prassolov, V. S., 2012, In: ACTA NATURAE. 3, 4, p. 55-65 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Similar incidences of TP53 deletions in extramedullary organ infiltrations, soft tissue and osteolyses of patients with multiple myeloma.
Billecke, L., Murga-Penas, E-M., May, A. M., Engelhardt, M., Nagler, A., Leiba, M., Schiby, G., Kröger, N., Zustin, J., Marx, A., Matschke, J., Tiemann, M., Goekkurt, E., Bokemeyer, C. & Schilling, G., 2012, In: ANTICANCER RES. 32, 5, p. 2031-2034 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SOCS3 promotes interleukin-17 expression of human T cells.
Kleinsteuber, K., Heesch, K., Schattling, S., Sander-Juelch, C., Mock, U., Riecken, K., Fehse, B., Fleischer, B. & Jacobsen, M., 2012, In: BLOOD. 120, 22, p. 4374-4382 22.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TET2 deletions are a recurrent but rare phenomenon in myeloid malignancies and are frequently accompanied by TET2 mutations on the remaining allele.
Bacher, U., Weissmann, S., Kohlmann, A., Schindela, S., Alpermann, T., Schnittger, S., Kern, W., Haferlach, T. & Haferlach, C., 2012, In: BRIT J HAEMATOL. 156, 1, p. 67-75 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The benefit of population-based studies for older patients with acute myeloid leukemia.
Bacher, U. & Haferlach, T., 2012, In: HAEMATOLOGICA. 97, 12, p. 1781-1782 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Therapy-related myeloid neoplasms following treatment with radioiodine.
Schroeder, T., Kuendgen, A., Kayser, S., Kröger, N., Braulke, F., Platzbecker, U., Klärner, V., Zohren, F., Haase, D., Stadler, M., Schlenk, R., Czibere, A. G., Bruns, I., Fenk, R., Gattermann, N., Haas, R., Kobbe, G. & Germing, U., 2012, In: HAEMATOLOGICA. 97, 2, p. 206-212 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The role of regulatory T cells and TH17 cells in multiple myeloma.
Braga, W. M. T., Atanackovic, D. & Colleoni, G. W. B., 2012, In: Clin Dev Immunol. 2012, p. 293479Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Three novel cytogenetically cryptic EVI1 rearrangements associated with increased EVI1 expression and poor prognosis identified in 27 acute myeloid leukemia cases.
Haferlach, C., Bacher, U., Grossmann, V., Schindela, S., Zenger, M., Kohlmann, A., Kern, W., Haferlach, T. & Schnittger, S., 2012, In: GENE CHROMOSOME CANC. 51, 12, p. 1079-1085 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Treatment of Ischemia/Reperfusion Injury of the Kidney with Mesenchymal Stromal Cells
Lange, C., Zander, A. R. & Westenfelder, C., 2012, Stem Cells and Cancer Stem Cells,Volume 3. Springer Berlin Heidelberg, p. 241-250 10 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Treatment, risk factors, and outcome of adults with relapsed AML after reduced intensity conditioning for allogeneic stem cell transplantation.
Schmid, C., Labopin, M., Nagler, A., Niederwieser, D., Castagna, L., Tabrizi, R., Stadler, M., Kuball, J., Cornelissen, J., Vorlicek, J., Socié, G., Falda, M., Vindeløv, L., Ljungman, P., Jackson, G., Kröger, N., Rank, A., Polge, E., Rocha, V., Mohty, M., Blood, A. L. W. P. O. T. E. G. F. & Transplantation, M., 2012, In: BLOOD. 119, 6, p. 1599-1606 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases.
Schnittger, S., Bacher, U., Alpermann, T., Reiter, A., Ulke, M., Dicker, F., Eder, C., Kohlmann, A., Grossmann, V., Kowarsch, A., Kern, W., Haferlach, C. & Haferlach, T., 2012, In: HAEMATOLOGICA. 97, 12, p. 1890-1894 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Purification of CD4+ T cells for adoptive immunotherapy after allogeneic hematopoietic stem cell transplantation
Klyuchnikov, E., Sputtek, A., Slesarchuk, O., Lioznov, M., Stübig, T., Bacher, U., Amtsfeld, G., Merle, E., Reckhaus, M-L., Fehse, B., Wolschke, C., Adjalle, R., Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 01.03.2011, In: BIOL BLOOD MARROW TR. 17, 3, p. 374-383 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells
Michaelis, M., Rothweiler, F., Barth, S., Cinatl, J., van Rikxoort, M., Löschmann, N., Voges, Y., Breitling, R., von Deimling, A., Rödel, F., Riecken, K., Fehse, B., Mack, E., Stiewe, T., Doerr, H. W., Speidel, D., Cinatl, J. & Riecken, K., 01.01.2011, In: CELL DEATH DIS. 2, p. e243Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A copy number repeat polymorphism in the transactivation domain of the CEPBA gene is possibly associated with a protective effect against acquired CEBPA mutations: an analysis in 1135 patients with AML and 187 healthy controls.
Schnittger, S., Bacher, U., Eder, C., Lohse, P., Haferlach, C., Kern, W. & Haferlach, T., 2011, In: EXP HEMATOL. 39, 1, p. 87-94 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Acute monoblastic/monocytic leukemia and chronic myelomonocytic leukemia share common immunophenotypic features but differ in the extent of aberrantly expressed antigens and amount of granulocytic cells.
Kern, W., Bacher, U., Haferlach, C., Schnittger, S. & Haferlach, T., 2011, In: LEUKEMIA LYMPHOMA. 52, 1, p. 92-100 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic stem cell transplantation for myelodysplastic syndromes with bone marrow fibrosis.
Kröger, N., Zabelina, T., van Biezen, A., Brand, R., Niederwieser, D., Martino, R., Lim, Z. Y., Onida, F., Schmid, C., Garderet, L., Robin, M., van Gelder, M., Marks, R., Symeonidis, A., Kobbe, G. & de Witte, T., 2011, In: HAEMATOLOGICA. 96, 2, p. 291-297 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Approaches to relapse after allogeneic stem cell transplantation.
Kröger, N., 2011, In: CURR OPIN ONCOL. 23, 2, p. 203-208 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Assessment of physiologic natural killer cell cytotoxicity in vitro.
Duske, H., Sputtek, A., Binder, T., Kröger, N., Schrepfer, S. & Eiermann, T., 2011, In: HUM IMMUNOL. 72, 11, p. 1007-1012 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review