Department of Stem Cell Transplantation
Publications
- 2010
Neue Wege der Stammzellforschung: Reprogrammierung von differenzierten Körperzellen
Beier, HM., Fehse, B., Friedrich, B., Götz, M., Hansmann, I., Hucho, F., Köchy, K., Müller-Röber, B., Rheinberger, HJ., Reich, J., Robpers, HH., Schöler, HR., Schöne-Seifert, B., Sperling, K., Tanner, K., Taupitz, J. & Wobus, AM., 2010, In: J Reprodmed Endokrinol. 7, p. 68-77Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neurogenic transdifferentiation of human adipose-derived stem cells? A critical protocol reevaluation with special emphasis on cell proliferation and cell cycle alterations.
Kompisch, K. M., Lange, C., Steinemann, D., Skawran, B., Schlegelberger, B., Müller, R. & Schumacher, U., 2010, In: HISTOCHEM CELL BIOL. 134, 5, p. 453-468 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Peptide length extension skews the minor HA-1 antigen presentation toward activated dendritic cells but reduces its presentation efficiency.
Hambach, L., Aghai, Z., Pool, J., Kröger, N. & Goulmy, E., 2010, In: J IMMUNOL. 185, 8, p. 4582-4589 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pilot study of rituximab plus donor-lymphocyte infusion to prevent or treat relapse in B-cell lymphoma after allogeneic stem cell transplantation.
Cavattoni, I., Zabelina, T., Ayuketang Ayuk, F., Wolschke, C., Bacher, U., Zander, A. R. & Kröger, N., 2010, In: LEUKEMIA LYMPHOMA. 51, 1, p. 146-148 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Post-transplant immune reconstitution after unrelated allogeneic stem cell transplant in patients with acute myeloid leukemia.
Klyuchnikov, E., Asenova, S., Kern, W., Kilinc, G., Ayuketang Ayuk, F., Wiedemann, B., Lioznov, M., Freiberger, P., Zalyalov, Y., Zander, A. R., Kröger, N. & Bacher, U., 2010, In: LEUKEMIA LYMPHOMA. 51, 8, p. 1450-1463 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Questionable role of free light chain assay ratio to determine stringent complete remission in multiple myeloma patients.
Kröger, N., Asenova, S., Gerritzen, A., Bacher, U. & Zander, A. R., 2010, In: BLOOD. 115, 16, p. 3413-3415 16.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduced-intensity conditioning followed by allogeneic hematopoietic stem cell transplantation in myelofibrosis.
Alchalby, H. & Kröger, N., 2010, In: CURR HEMATOL MALIG R. 5, 2, p. 53-61 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Screening and monitoring of MPL W515L mutation with real-time PCR in patients with myelofibrosis undergoing allogeneic-SCT.
Alchalby, H., Badbaran, A., Bock, O., Fehse, B., Bacher, U., Zander, A. R. & Kröger, N., 2010, In: BONE MARROW TRANSPL. 45, 9, p. 1404-1407 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Second Allogeneic Stem Cell Transplantation in a Patient with Hypoplastic Myelodysplastic Syndrome following a Primary Diagnosis of Aplastic Anaemia.
Ocheni, S., Oyekunle, A., Kröger, N., Ayuketang Ayuk, F., Klyuchnikov, E., Arps, S., Held, K., Zabelina, T., Adjalle, R., Wolschke, C., Zander, A. R. & Bacher, U., 2010, In: ACTA HAEMATOL-BASEL. 125, 3, p. 175-178 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Solid organ transplantation after allogeneic hematopoietic stem cell transplantation: a retrospective, multicenter study of the EBMT.
Koenecke, C., Hertenstein, B., Schetelig, J., van Biezen, A., Dammann, E., Gratwohl, A., Ganser, A., Schleuning, M., Bornhäuser, M., Jacobsen, N., Kröger, N., Niederwieser, D., de Witte, T. & Ruutu, T., 2010, In: AM J TRANSPLANT. 10, 8, p. 1897-1906 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The cytokine/chemokine pattern in the bone marrow environment of multiple myeloma patients.
Cao, Y., Luetkens, T., Kobold, S., Hildebrandt, Y., Gordic, M., Lajmi, N., Meyer, S., Bartels, K., Zander, A. R., Bokemeyer, C., Kröger, N. & Atanackovic, D., 2010, In: EXP HEMATOL. 38, 10, p. 860-867 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The MSCs' in vitro community: where to go?
Lange, S., Zander, A. R. & Lange, C., 2010, In: CTT-Cell Ther Transpl. 1, 4, p. 1 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The role of multiparameter flow cytometry for disease monitoring in AML.
Kern, W., Bacher, U., Haferlach, C., Schnittger, S. & Haferlach, T., 2010, In: BEST PRACT RES CL HA. 23, 3, p. 379-390 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TK.007: A novel, codon-optimized HSVtk(A168H) mutant for suicide gene therapy.
Preuß, E., Treschow, A., Newrzela, S., Brücher, D., Riecken, K., Felldin, U., Alici, E., Gahrton, G., von Laer, D., Dilber, M. S. & Fehse, B., 2010, In: HUM GENE THER. 21, 8, p. 929-941 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Unrelated stem cell transplantation after reduced intensity conditioning for patients with multiple myeloma relapsing after autologous transplantation.
Kröger, N., Shimoni, A., Schilling, G., Schwerdtfeger, R., Bornhäuser, M., Nagler, A., Zander, A. R., Heinzelmann, M., Brand, R., Gahrton, G., Morris, C., Niederwieser, D. & de Witte, T., 2010, In: BRIT J HAEMATOL. 148, 2, p. 323-331 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Unrelated stem cell transplantation for patients with multiple myeloma.
Kröger, N., 2010, In: CURR OPIN HEMATOL. 17, 6, p. 538-543 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
PKR activity is required for acute leukemic cell maintenance and growth: a role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation
Blalock, W. L., Grimaldi, C., Fala, F., Follo, M., Horn, S., Basecke, J., Martinelli, G., Cocco, L. & Martelli, A. M., 01.10.2009, In: J CELL PHYSIOL. 221, 1, p. 232-41 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Platelet derived bFGF mediates vascular integrative mechanisms of mesenchymal stem cells in vitro
Langer, H. F., Stellos, K., Steingen, C., Froihofer, A., Schönberger, T., Krämer, B., Bigalke, B., May, A. E., Seizer, P., Müller, I., Gieseke, F., Siegel-Axel, D., Meuth, S. G., Schmidt, A., Wendel, H. P., Müller, I., Bloch, W. & Gawaz, M., 08.2009, In: J MOL CELL CARDIOL. 47, 2, p. 315-25 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diffusion-driven device for a high-resolution dose-response profiling of combination chemotherapy
Ganser, A., Roth, G., van Galen, J. C., Hilderink, J., Wammes, J. J. G., Müller, I., van Leeuwen, F. N., Wiesmüller, K-H. & Brock, R., 01.07.2009, In: ANAL CHEM. 81, 13, p. 5233-40 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dendritic cells: functional aspects of glycosylation and lectins
Erbacher, A., Gieseke, F., Handgretinger, R. & Müller, I., 05.2009, In: HUM IMMUNOL. 70, 5, p. 308-12 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Isolation of functionally distinct mesenchymal stem cell subsets using antibodies against CD56, CD271, and mesenchymal stem cell antigen-1
Battula, V. L., Treml, S., Bareiss, P. M., Gieseke, F., Roelofs, H., de Zwart, P., Müller, I., Schewe, B., Skutella, T., Fibbe, W. E., Kanz, L. & Bühring, H-J., 02.2009, In: HAEMATOLOGICA. 94, 2, p. 173-84 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
5-Azacytidine for the treatment of patients with acute myeloid leukemia or myelodysplastic syndrome who relapse after allo-SCT: a retrospective analysis.
Czibere, A., Bruns, I., Kröger, N., Platzbecker, U., Lind, J., Zohren, F., Fenk, R., Germing, U., Schröder, T., Gräf, T., Haas, R. & Kobbe, G., 2009, In: BONE MARROW TRANSPL. *45*, 5, p. 872-876 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic hematopoietic stem cell transplantation (allo SCT) for chronic myeloid leukemia in the imatinib era: evaluation of its impact within a subgroup of the randomized German CML Study IV.
Saussele, S., Lauseker, M., Gratwohl, A., Beelen, D. W., Bunjes, D., Schwerdtfeger, R., Kolb, H-J., Ho, A. D., Falge, C., Holler, E., Schlimok, G., Zander, A. R., Arnold, R., Kanz, L., Dengler, R., Haferlach, C., Schlegelberger, B., Pfirrmann, M., Muller, M. C., Schnittger, S., Leitner, A., Pletsch, N., Hochhaus, A., Hasford, J. & Hehlmann, R., 2009, In: BLOOD. *115*, 10, p. 1880-1885 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation.
Kröger, N., Holler, E., Kobbe, G., Bornhäuser, M., Schwerdtfeger, R., Baurmann, H., Nagler, A., Bethge, W., Stelljes, M., Uharek, L., Wandt, H., Burchert, A., Corradini, P., Schubert, J., Kaufmann, M., Dreger, P., Wulf, G. G., Einsele, H., Zabelina, T., Kvasnicka, H. M., Thiele, J., Brand, R., Zander, A. R., Niederwieser, D., Witte, D. & Theo, M., 2009, In: BLOOD. 114, 26, p. 5264-5270 26.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic stem cell transplantation for patients with refractory anaemia with matched related and unrelated donors: delay of the transplant is associated with inferior survival.
de Witte, T., Brand, R., van Biezen, A., Mufti, G., Ruutu, T., Finke, J., von Dem Borne, P., Vitek, A., Delforge, M., Alessandrino, P., Harlahakis, N., Russell, N., Martino, R., Verdonck, L., Kröger, N. & Niederwieser, D., 2009, In: BRIT J HAEMATOL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
AML with translocation t(8;16)(p11;p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features.
Haferlach, T., Kohlmann, A., Klein, H-U., Ruckert, C., Dugas, M., Williams, P. M., Kern, W., Schnittger, S., Bacher, U., Löffler, H. & Haferlach, C., 2009, In: LEUKEMIA. 23, 5, p. 934-943 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Antitumor effects of polyclonal antithymocyte globulins: focus on B-cell malignancies and multiple myeloma.
Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 2009, In: ANN HEMATOL. 88, 5, p. 401-404 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A retrospective comparison of conventional intensity conditioning and reduced-intensity conditioning for allogeneic hematopoietic cell transplantation in myelofibrosis.
Gupta, V., Kröger, N., Aschan, J., Xu, W., Leber, B., Dalley, C., Sabloff, M., Lipton, J. H., Messner, H. & Brune, M., 2009, In: BONE MARROW TRANSPL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Basic research and clinical applications of non-hematopoietic stem cells, 4-5 April 2008, Tubingen, Germany
Schäfer, R., Dominici, M., Müller, I., Horwitz, E., Asahara, T., Bulte, J. W. M., Bieback, K., Le Blanc, K., Bühring, H. J., Capogrossi, M. C., Dazzi, F., Gorodetsky, R., Henschler, R., Handgretinger, R., Kajstura, J., Kluger, P. J., Lange, C., Luettichau, I. V., Mertsching, H., Schrezenmeier, H., Sievert, K. D., Strunk, D., Verfaillie, C. & Northoff, H., 2009, In: CYTOTHERAPY. 11, 2, p. 245-55 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biclonal expansion and heterogeneous lineage involvement in a case of chronic myeloproliferative disease with concurrent MPLW515L/JAK2V617F mutation.
Hussein, K., Bock, O., Theophile, K., Schlue, J., Ballmaier, M., Kröger, N., Göhring, G., Büsche, G. & Kreipe, H., 2009, In: BLOOD. 113, 6, p. 1391-1392 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone marrow mesenchymal stromal cells remain of recipient origin after allogeneic SCT and do not harbor the JAK2V617F mutation in patients with myelofibrosis.
Bacher, U., Asenova, S., Badbaran, A., Zander, A. R., Alchalby, H., Fehse, B., Kröger, N., Lange, C. & Ayuketang Ayuk, F., 2009, In: CLIN EXP MED.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer-testis antigens MAGE-C1/CT7 and MAGE-A3 promote the survival of multiple myeloma cells.
Atanackovic, D., Hildebrandt, Y., Jadczak, A., Cao, Y., Luetkens, T., Meyer, S., Kobold, S., Bartels, K., Pabst, C., Lajmi, N., Gordic, M., Stahl, T., Zander, A. R., Bokemeyer, C. & Kröger, N., 2009, In: HAEMATOLOGICA. *95*, 5, p. 785-793 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterisation of extramedullary relapse in patients with chronic myeloid leukemia in advanced disease after allogeneic stem cell transplantation.
Ocheni, S., Iwanski, G., Schafhausen, P., Zander, A. R., Ayuketang Ayuk, F., Klyuchnikov, E., Zabelina, T., Fiedler, W., Schnittger, S., Hochhaus, A., Brümmendorf, T., Kröger, N. & Bacher, U., 2009, In: LEUKEMIA LYMPHOMA. 50, 4, p. 551-558 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of 35 new cases with four different MPLW515 mutations and essential thrombocytosis or primary myelofibrosis.
Schnittger, S., Bacher, U., Haferlach, C., Beelen, D., Bojko, P., Bürkle, D., Dengler, R., Distelrath, A., Eckart, M., Eckert, R., Fries, S., Knoblich, J., Köchling, G., Laubenstein, H-P., Petrides, P., Planker, M., Pihusch, R., Weide, R., Kern, W. & Haferlach, T., 2009, In: HAEMATOLOGICA. 94, 1, p. 141-144 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of the cytotoxicity of 4 preparations of anti-T-cell globulins in various hematological malignancies.
Ayuketang Ayuk, F., Maywald, N., Hannemann, S., Larsen, U., Zander, A. R. & Kröger, N., 2009, In: ANTICANCER RES. 29, 4, p. 1355-1360 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Concordance of assays designed for the quantification of JAK2V617F: a multicenter study.
Lippert, E., Girodon, F., Hammond, E., Jelinek, J., Reading, N. S., Fehse, B., Hanlon, K., Hermans, M., Richard, C., Swierczek, S., Ugo, V., Carillo, S., Harrivel, V., Marzac, C., Pietra, D., Sobas, M., Mounier, M., Migeon, M., Ellard, S., Kröger, N., Herrmann, R., Prchal, J. T., Skoda, R. C. & Hermouet, S., 2009, In: HAEMATOLOGICA. 94, 1, p. 38-45 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Current status and perspectives of tyrosine kinase inhibitor treatment in the post-transplant period in patients with chronic myeloid leukemia (CML).
Klyuchnikov, E., Kröger, N., Brümmendorf, T., Wiedemann, B., Zander, A. R. & Bacher, U., 2009, In: BIOL BLOOD MARROW TR.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Current status of gene expression profiling in the diagnosis and management of acute leukaemia.
Bacher, U., Kohlmann, A. & Haferlach, T., 2009, In: BRIT J HAEMATOL. 145, 5, p. 555-568 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of JAK2 exon 12 mutations in 15 patients with JAK2V617F negative polycythemia vera.
Schnittger, S., Bacher, U., Haferlach, C., Geer, T., Müller, P., Mittermüller, J., Petrides, P., Schlag, R., Sandner, R., Selbach, J., Slawik, H. R., Tessen, H. W., Wehmeyer, J., Kern, W. & Haferlach, T., 2009, In: HAEMATOLOGICA. 94, 3, p. 414-418 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Development of AML with t(8;21)(q22;q22) and RUNX1-RUNX1T1 fusion following Philadelphia-negative clonal evolution during treatment of CML with Imatinib.
Schafhausen, P., Dierlamm, J., Bokemeyer, C., Brümmendorf, T., Bacher, U., Zander, A. R., Schnittger, S. & Hochhaus, A., 2009, In: CANCER GENET-NY. 189, 1, p. 63-67 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Discussion of the applicability of microarrays: profiling of leukemias.
Haferlach, T., Bacher, U., Kohlmann, A. & Haferlach, C., 2009, In: Methods Mol Biol. 509, p. 15-33Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distribution of cytogenetic abnormalities in myelodysplastic syndromes, Philadelphia negative myeloproliferative neoplasms, and the overlap MDS/MPN category.
Bacher, U., Schnittger, S., Kern, W., Weiss, T., Haferlach, T. & Haferlach, C., 2009, In: ANN HEMATOL. 88, 12, p. 1207-1213 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diva-Fit: A step-by-step manual for generating high-resolution graphs and histogram overlays of flow cytometry data obtained with FACSDiva software
Riecken, K. & Fehse, B., 2009, In: CTT-Cell Ther Transpl. 1, 4, p. 1-4 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Donor lymphocyte infusions in amyloid light chain amyloidosis: induction of a "graft-versus-plasma cell-dyscrasia effect".
Schonland, S. O., Kröger, N., Wolschke, C., Dreger, P., Ho, A. D. & Hegenbart, U., 2009, In: HAEMATOLOGICA. 94, 3, p. 439-441 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Endocardial electrogram analysis after intramyocardial injection of mesenchymal stem cells in the chronic ischemic myocardium.
Krause, K., Schneider, C., Lange, C., Kokturk, B., Boczor, S., Geidel, S., Salhi, A., Alaser, J., Zander, A. R., Kuck, K-H. & Jaquet, K., 2009, In: PACE. 32, 10, p. 1319-1328 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Flow cytometric identification of acute myeloid leukemia with limited differentiation and NPM1 type A mutation: a new biologically defined entity.
Kern, W., Haferlach, C., Bacher, U., Haferlach, T. & Schnittger, S., 2009, In: LEUKEMIA. 23, 7, p. 1361-1364 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene expression profiling in acute myeloid leukaemia (AML).
Bacher, U., Kohlmann, A., Haferlach, C. & Haferlach, T., 2009, In: BEST PRACT RES CL HA. 22, 2, p. 169-180 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HLA-mismatched unrelated donors as an alternative graft source for allogeneic stem cell transplantation after antithymocyte globulin-containing conditioning regimen.
Kröger, N., Zabelina, T., Binder, T., Ayuketang Ayuk, F., Bacher, U., Amtsfeld, G., Lellek, H., Schrum, J., Erttmann, R., Eiermann, T. & Zander, A. R., 2009, In: BIOL BLOOD MARROW TR. 15, 4, p. 454-462 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of new target molecules PTK2, TGFBR2 and CD9 overexpressed during advanced bone marrow remodelling in primary myelofibrosis.
Bock, O., Muth, M., Theophile, K., Winter, M., Hussein, K., Büsche, G., Kröger, N. & Kreipe, H., 2009, In: BRIT J HAEMATOL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interactive diagnostics in the indication to allogeneic SCT in AML.
Bacher, U., Haferlach, C., Schnittger, S., Kern, W., Kröger, N., Zander, A. R. & Haferlach, T., 2009, In: BONE MARROW TRANSPL. 43, 10, p. 745-756 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review