The cytokine/chemokine pattern in the bone marrow environment of multiple myeloma patients.

  • Yanran Cao
  • Tim Luetkens
  • Sebastian Kobold
  • York Hildebrandt
  • Maja Gordic
  • Nesrine Lajmi
  • Sabrina Meyer
  • Katrin Bartels
  • Axel R. Zander
  • Carsten Bokemeyer
  • Nicolaus Kröger
  • Djordje Atanackovic

Abstract

The interaction of multiple myeloma (MM) with its bone marrow (BM) microenvironment is important for the homing pattern, survival, and proliferation of malignant plasma cells. We aimed at answering the question which cytokines, chemokines, and growth factors are typically found in the BM of untreated MM patients as well as in MM patients after allogeneic stem cell transplantation (alloSCT).

Bibliographical data

Original languageGerman
Article number10
ISSN0301-472X
Publication statusPublished - 2010
pubmed 20619313