Institute of Medical Microbiology, Virology and Hygiene

Publications

  1. 2021
  2. Prospective postmortem evaluation of 735 consecutive SARS-CoV-2-associated death cases

    Fitzek, A., Schädler, J., Dietz, E., Ron, A., Gerling, M., Kammal, A. L., Lohner, L., Falck, C., Möbius, D., Goebels, H., Gerberding, A-L., Schröder, A. S., Sperhake, J-P., Klein, A., Fröb, D., Mushumba, H., Wilmes, S., Anders, S., Kniep, I., Heinrich, F., Langenwalder, F., Meißner, K., Lange, P., Zapf, A., Püschel, K., Heinemann, A., Glatzel, M., Matschke, J., Aepfelbacher, M., Lütgehetmann, M., Steurer, S., Thorns, C., Edler, C. & Ondruschka, B., 29.09.2021, In: SCI REP-UK. 11, 1, p. 19342

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Complete genome sequencing and molecular characterization of SARS-COV-2 from COVID-19 cases in Alborz province in Iran

    Kaffashi, A., Huang, J., Bairami, A., Fallah Mehrabadi, M. H., Yaslianifard, S., Bashashati, M., Banihashemi, S. R., Soleimanifar, F., Lotfi, M., Taghizadeh, M., Soleimani, A., Khorasani, A., Moshiri, F. & Mozhgani, S-H., 17.09.2021, In: HELIYON. 7, 9, e08027.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. KIR3DS1 directs NK cell-mediated protection against human adenovirus infections

    Jung, J. M., Ching, W., Baumdick, M. E., Hofmann-Sieber, H., Bosse, J. B., Koyro, T., Möller, K. J., Wegner, L., Niehrs, A., Russu, K., Ohms, M., Zhang, W., Ehrhardt, A., Duisters, K., Spierings, E., Hölzemer, A., Körner, C., Jansen, S. A., Peine, S., Königs, I., Lütgehetmann, M., Perez, D., Reinshagen, K., Lindemans, C. A., Altfeld, M., Belderbos, M., Dobner, T. & Bunders, M. J., 17.09.2021, In: SCI IMMUNOL. 6, 63, eabe2942.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Bacteriophage Rescue Therapy of a Vancomycin-Resistant Enterococcus faecium Infection in a One-Year-Old Child following a Third Liver Transplantation

    Paul, K., Merabishvili, M., Hazan, R., Christner, M., Herden, U., Gelman, D., Khalifa, L., Yerushalmy, O., Coppenhagen-Glazer, S., Harbauer, T., Schulz-Jürgensen, S., Rohde, H., Fischer, L., Aslam, S., Rohde, C., Nir-Paz, R., Pirnay, J-P., Singer, D. & Muntau, A. C., 07.09.2021, In: VIRUSES-BASEL. 13, 9, p. 1785

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19

    Heide, J., Schulte, S., Kohsar, M., Brehm, T. T., Herrmann, M., Karsten, H., Marget, M., Peine, S., Johansson, A. M., Sette, A., Lütgehetmann, M., Kwok, W. W., Sidney, J. & Schulze Zur Wiesch, J., 09.2021, In: PLOS PATHOG. 17, 9, e1009842.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model

    Heyckendorf, J., Marwitz, S., Reimann, M., Avsar, K., DiNardo, A., Günther, G., Hoelscher, M., Ibraim, E., Kalsdorf, B., Kaufmann, S. H. E., Kontsevaya, I., van Leth, F., Mandalakas, A. M., Maurer, F. P., Müller, M., Nitschkowski, D., Olaru, I. D., Popa, C., Rachow, A., Rolling, T., Rybniker, J., Salzer, H. J. F., Sanchez-Carballo, P., Schuhmann, M., Schaub, D., Spinu, V., Suárez, I., Terhalle, E., Unnewehr, M., Weiner, J., Goldmann, T. & Lange, C., 09.2021, In: EUR RESPIR J. 58, 3, p. 2003492

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. The Emerging Role of Iron Acquisition in Biofilm-Associated Infections

    Oliveira, F., Rohde, H., Vilanova, M. & Cerca, N., 09.2021, In: TRENDS MICROBIOL. 29, 9, p. 772-775 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  9. The handling of SARS-CoV-2 associated deaths - infectivity of the body

    Schröder, A. S., Edler, C., Ondruschka, B., Püschel, K., Schädler, J., Heinemann, A., Heinrich, F., Lütgehetmann, M., Pfefferle, S., Aepfelbacher, M., Fitzek, A. & Sperhake, J-P., 09.2021, In: FORENSIC SCI MED PAT. 17, 3, p. 411-418 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Intestinal Colonization with Tropheryma whipplei—Clinical and Immunological Implications for HIV Positive Adults in Ghana

    Eberhardt, K. A., Sarfo, F. S., Klupp, E-M., Dompreh, A., Cristanziano, V. D., Kuffour, E. O., Boateng, R., Norman, B., Phillips, R. O., Aepfelbacher, M. & Feldt, T., 22.08.2021, In: MICROORGANISMS. 9, 8, p. 1781

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Comparison of Two Real-Time PCR Assays Targeting Ribosomal Sequences for the Identification of Cystoisospora belli in Human Stool Samples

    Blohm, M., Hahn, A., Hagen, R. M., Eberhardt, K. A., Rohde, H., Leboulle, G., Feldt, T., Sarfo, F. S., Cristanziano, V. D., Frickmann, H. & Loderstädt, U., 19.08.2021, In: PATHOGENS. 10, 8

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Vertically transferred maternal immune cells promote neonatal immunity against early life infections

    Stelzer, I., Urbschat, C., Schepanski, S., Thiele, K., Triviai, I., Wieczorek, A., Alawi, M., Ohnezeit, D., Kottlau, J., Huang, J., Fischer, N., Mittrücker, H-W., Solano, M. E., Fehse, B., Diemert, A., Stahl, F. & Arck, P., 04.08.2021, In: NAT COMMUN. 12, 1, p. 4706

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Benchmark of thirteen bioinformatic pipelines for metagenomic virus diagnostics using datasets from clinical samples

    de Vries, J. J. C., Brown, J. R., Fischer, N., Sidorov, I. A., Morfopoulou, S., Huang, J., Munnink, B. B. O., Sayiner, A., Bulgurcu, A., Rodriguez, C., Gricourt, G., Keyaerts, E., Beller, L., Bachofen, C., Kubacki, J., Samuel, C., Florian, L., Dennis, S., Beer, M., Hoeper, D., Huber, M., Kufner, V., Zaheri, M., Lebrand, A., Papa, A., van Boheemen, S., Kroes, A. C. M., Breuer, J., Lopez-Labrador, F. X., Claas, E. C. J. & ESCV Network on Next-Generation Sequencing, 08.2021, In: J CLIN VIROL. 141, 104908.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Innate immunity in hepatitis B and D virus infection: consequences for viral persistence, inflammation, and T cell recognition

    Dandri, M., Bertoletti, A. & Lütgehetmann, M., 08.2021, In: SEMIN IMMUNOPATHOL. 43, 4, p. 535-548 14 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  15. Nicht-Cholera-Vibrionen – derzeit noch seltene, aber wachsende Infektionsgefahr in Nord- und Ostsee

    Brehm, T. T., Dupke, S., Hauk, G., Fickenscher, H., Rohde, H. & Berneking, L., 08.2021, In: INTERNIST. 62, 8, p. 876-886 11 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  16. Telmisartan induces a specific gut microbiota signature which may mediate its antiobesity effect

    Beckmann, L., Künstner, A., Freschi, M. L., Huber, G., Stölting, I., Ibrahim, S. M., Hirose, M., Freitag, M., Langan, E. A., Matschl, U., Galuska, C. E., Fuchs, B., Knobloch, J. K., Busch, H. & Raasch, W., 08.2021, In: PHARMACOL RES. 170, 105724.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Usefulness of Biofire FilmArray BCID2 for blood culture processing in clinical practice

    Berinson, B., Both, A., Berneking, L., Christner, M., Lütgehetmann, M., Aepfelbacher, M. & Rohde, H., 19.07.2021, In: Journal of Clinical Microbiology. 59, 8, p. e0054321 e0054321.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Development of the "Hamburg Best Practice Guidelines for ICV-Enzyme Replacement therapy (ERT) in CLN2 Disease" Based on 6 Years Treatment Experience in 48 Patients

    Schwering, C., Kammler, G., Wibbeler, E., Christner, M., Knobloch, J. K-M., Nickel, M., Denecke, J., Baehr, M. & Schulz, A., 07.2021, In: J CHILD NEUROL. 36, 8, p. 635-641 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Hepatitis E virus persists in the ejaculate of chronically infected men

    Horvatits, T., Wißmann, J-E., Johne, R., Groschup, M. H., Gadicherla, A. K., Wiesch, J. S. Z., Eiden, M., Todt, D., Reimer, R., Dähnert, L., Schöbel, A., Horvatits, K., Lübke, R., Wolschke, C., Ayuk, F., Rybczynski, M., Lohse, A. W., Addo, M. M., Herker, E., Lütgehetmann, M., Steinmann, E. & Pischke, S., 07.2021, In: J HEPATOL. 75, 1, p. 55-63 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Practical recommendations for routine cleaning and disinfection procedures in healthcare institutions: a narrative review

    Assadian, O., Harbarth, S., Vos, M., Knobloch, J. K., Asensio, A. & Widmer, A. F., 07.2021, In: J HOSP INFECT. 113, p. 104-114 11 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  21. Fatal COVID-19 in a Child with Persistence of SARS-CoV-2 Despite Extensive Multidisciplinary Treatment: A Case Report

    Apostolidou, S., Harbauer, T., Lasch, P., Biermann, D., Hempel, M., Lütgehetmann, M., Pfefferle, S., Herrmann, J., Rüffer, A., Reinshagen, K., Kozlik-Feldmann, R., Gieras, A., Kniep, I., Oh, J., Singer, D., Ebenebe, C. U. & Kobbe, R., 30.06.2021, In: CHILDREN-BASEL. 8, 7, 564.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Molecular Mechanisms of Borrelia burgdorferi Phagocytosis and Intracellular Processing by Human Macrophages

    Woitzik, P. & Linder, S., 22.06.2021, In: BIOLOGY-BASEL. 10, 7, p. 567

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  23. An automated room disinfection system using ozone is highly active against surrogates for SARS-CoV-2

    Franke, G., Knobling, B., Brill, F. H., Becker, B., Klupp, E. M., Belmar Campos, C., Pfefferle, S., Lütgehetmann, M. & Knobloch, J. K., 06.2021, In: J HOSP INFECT. 112, p. 108-113 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Bacterial adhesion characteristics on implant materials for intervertebral cages: titanium or PEEK for spinal infections?

    Krätzig, T., Mende, K. C., Mohme, M., von Kroge, S., Stangenberg, M., Dreimann, M., Westphal, M., Weisselberg, S. & Eicker, S. O., 06.2021, In: EUR SPINE J. 30, 6, p. 1774-1782 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Modifying a Diagnostic SARS-CoV-2 Spike PCR to Turn a Del69/70 Dropout into a Discriminatory On-Target Assay

    Nörz, D., Pfefferle, S., Grunwald, M., Fischer, N., Aepfelbacher, M. & Lütgehetmann, M., 06.2021, In: J MOL DIAGN. 23, 6, p. 777-778 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  26. Staphylococcus epidermidis clones express Staphylococcus aureus-type wall teichoic acid to shift from a commensal to pathogen lifestyle

    Du, X., Larsen, J., Li, M., Walter, A., Slavetinsky, C., Both, A., Sanchez Carballo, P. M., Stegger, M., Lehmann, E., Liu, Y., Liu, J., Slavetinsky, J., Duda, K. A., Krismer, B., Heilbronner, S., Weidenmaier, C., Mayer, C., Rohde, H., Winstel, V. & Peschel, A., 06.2021, In: NAT MICROBIOL. 6, 6, p. 757-768 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. HEV-Associated Neuralgic Amyotrophy : A Multicentric Case Series

    Bannasch, J. H., Berger, B., Schwartkopp, C-P., Berning, M., Goetze, O., Panning, M., Fritz-Weltin, M., Trendelenburg, G., Gelderblom, M., Lütgehetmann, M., Stute, F., Horvatits, T., Dirks, M., Antoni, C., Behrendt, P. & Pischke, S., 30.05.2021, In: PATHOGENS. 10, 6, 672.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Cefiderocol in Critically Ill Patients with Multi-Drug Resistant Pathogens: Real-Life Data on Pharmacokinetics and Microbiological Surveillance

    König, C., Both, A., Rohde, H., Kluge, S., Frey, O. R., Röhr, A. C. & Wichmann, D., 28.05.2021, In: ANTIBIOTICS-BASEL. 10, 6, p. 649 649.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. An inter‑laboratory study to investigate the impact of the bioinformatics component on microbiome analysis using mock communities

    O’Sullivan, D., Doyle, R., Temisak, S., Redshaw, N., Whale, A., Logan, G., Huang, J., Fischer, N., Amos, G., Preston, M., Marchesi, J., Wagner, J., Parkhill, J., Motro, Y., Denise, H., Finn, R., Kay, G., O'Grady, J., Ransom-Jones, E., Wu, H., Laing, E., Benavente, E., Phelan, J., Clark, T., Moran-Gilad, J. & Huggett, J., 19.05.2021, In: SCI REP-UK. 11, 1, p. 10590

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Implementation of a multidisciplinary infections conference improves the treatment of spondylodiscitis

    Ntalos, D., Schoof, B., Thiesen, D. M., Viezens, L., Kleinertz, H., Rohde, H., Both, A., Luebke, A., Strahl, A., Dreimann, M. & Stangenberg, M., 04.05.2021, In: SCI REP-UK. 11, 1, p. 9515

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Performance of the BD Phoenix CPO detect assay for detection and classification of carbapenemase-producing organisms

    Berneking, L., Both, A., Berinson, B., Hoffmann, A., Lütgehetmann, M., Aepfelbacher, M. & Rohde, H., 05.2021, In: EUR J CLIN MICROBIOL. 40, 5, p. 979-985 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Recommendations for the introduction of metagenomic next-generation sequencing in clinical virology, part II:bioinformatic analysis and reporting

    de Vries, J. J. C., Brown, J. R., Couto, N., Beer, M., Le Mercier, P., Sidorov, I., Papa, A., Fischer, N., Oude Munnink, B. B., Rodriquez, C., Zaheri, M., Sayiner, A., Hönemann, M., Cataluna, A. P., Carbo, E. C., Bachofen, C., Kubacki, J., Schmitz, D., Tsioka, K., Matamoros, S., Höper, D., Hernandez, M., Puchhammer-Stöckl, E., Lebrand, A., Huber, M., Simmonds, P., Claas, E. C. J., López-Labrador, F. X. & ESCV Network on Next-Generation Sequencing, 05.2021, In: J CLIN VIROL. 138, 104812.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Retrospective analysis of bacterial colonization of necrotic bone and antibiotic resistance in 98 patients with medication-related osteonecrosis of the jaw (MRONJ)

    Ewald, F., Wuesthoff, F., Koehnke, R., Friedrich, R. E., Gosau, M., Smeets, R., Rohde, H. & Assaf, A. T., 05.2021, In: CLIN ORAL INVEST. 25, 5, p. 2801-2809 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Upregulation of HLA-F expression by BK polyomavirus infection induces immune recognition by KIR3DS1-positive natural killer cells

    Koyro, T. F., Kraus, E., Lunemann, S., Hölzemer, A., Wulf, S., Jung, J., Fittje, P., Henseling, F., Körner, C., Huber, T. B., Grundhoff, A., Wiech, T., Panzer, U., Fischer, N. & Altfeld, M., 05.2021, In: KIDNEY INT. 99, 5, p. 1140-1148 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. SARS-CoV-2-Zufallsentdeckungen bei Hamburger Todesfällen: ein epidemiologisches Monitoring während des dynamischen Infektionsgeschehens im Frühjahr 2020

    Klein, A., Langenwalder, F., Heinrich, F., Meißner, K., Schröder, A. S., Püschel, K., Ondruschka, B., Lütgehetmann, M. & Heinemann, A., 20.04.2021, In: RECHTSMEDIZIN. 31, p. 427-433 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Less than you'd think-a prospective study on MRSA-colonization in healthy travellers

    Tran, DT., Winter, D., Christner, M., Ramharter, M., Addo, M. M., Rolling, T., Vinnemeier, C. & Koch, T., 14.04.2021, In: J TRAVEL MED. 28, 3, taaa242.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. EUCAST rapid antimicrobial susceptibility testing (RAST): analytical performance and impact on patient management

    Berinson, B., Olearo, F., Both, A., Brossmann, N., Christner, M., Aepfelbacher, M. & Rohde, H., 13.04.2021, In: J ANTIMICROB CHEMOTH. 76, 5, p. 1332-1338 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies

    Brehm, T. T., Pfefferle, S., von Possel, R., Kobbe, R., Nörz, D., Schmiedel, S., Grundhoff, A., Olearo, F., Emmerich, P., Robitaille, A., Günther, T., Braun, P., Andersen, G., Knobloch, J. K., Addo, M. M., Lohse, A. W., Aepfelbacher, M., Fischer, N., Schulze Zur Wiesch, J. & Lütgehetmann, M., 12.04.2021, In: VIRUSES-BASEL. 13, 4, 661.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearch

  39. Presence of SARS-CoV-2 RNA in the Cornea of Viremic Patients With COVID-19

    Casagrande, M., Fitzek, A., Spitzer, M. S., Püschel, K., Glatzel, M., Krasemann, S., Nörz, D., Lütgehetmann, M., Pfefferle, S. & Schultheiss, M., 01.04.2021, In: JAMA OPHTHALMOL. 139, 4, p. 383-388 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Clinical evaluation of a laboratory-developed quantitative BK virus-PCR assay using the cobas® omni Utility Channel

    Fritzsche, A., Berneking, L., Nörz, D., Reucher, S., Fischer, N., Roggenkamp, H., Aepfelbacher, M., Rohde, H., Pfefferle, S. & Lütgehetmann, M., 04.2021, In: J VIROL METHODS. 290, p. 114093

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Severe liver dysfunction complicating course of COVID-19 in the critically ill: multifactorial cause or direct viral effect?

    Roedl, K., Jarczak, D., Drolz, A., Wichmann, D., Boenisch, O., de Heer, G., Burdelski, C., Frings, D., Sensen, B., Nierhaus, A., Lütgehetmann, M., Kluge, S. & Fuhrmann, V., 15.03.2021, In: ANN INTENSIVE CARE. 11, 1, 44.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Comparison of clinical characteristics and disease outcome of COVID-19 and seasonal influenza

    Brehm, T. T., van der Meirschen, M., Hennigs, A., Roedl, K., Jarczak, D., Wichmann, D., Frings, D., Nierhaus, A., Oqueka, T., Fiedler, W., Christopeit, M., Kraef, C., Schultze, A., Lütgehetmann, M., Addo, M. M., Schmiedel, S., Kluge, S. & Schulze Zur Wiesch, J., 11.03.2021, In: SCI REP-UK. 11, 1, 5803.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Host factors abolish the need for polysaccharides and extracellular matrix-binding protein in Staphylococcus epidermidis biofilm formation

    Skovdal, S. M., Hansen, L. K., Ivarsen, D. M., Zeng, G., Büttner, H., Rohde, H., Jørgensen, N. P. & Meyer, R. L., 03.2021, In: J MED MICROBIOL. 70, 3

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Seroprevalence of SARS-CoV-2 antibodies among hospital workers in a German tertiary care center: A sequential follow-up study

    Brehm, T. T., Schwinge, D., Lampalzer, S., Schlicker, V., Küchen, J., Thompson, M., Ullrich, F., Huber, S., Schmiedel, S., Addo, M. M., Lütgehetmann, M., Knobloch, J. K., Schulze Zur Wiesch, J. & Lohse, A. W., 03.2021, In: INT J HYG ENVIR HEAL. 232, 113671.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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