Institute of Medical Microbiology, Virology and Hygiene

Publications

  1. 2024
  2. BCMA x CD3 T-cell engager in a patient with penta-refractory multiple myeloma and HIV: a clinical and immunological report

    Cords, L., Schaefers, C., Kamili, A., Hoffmann, C., Cichutek, S., Haag, F., Polywka, S., Bokemeyer, C., Leypoldt, L. B., Alsdorf, W., Schulze zur Wiesch, J. & Weisel, K. C., 01.09.2024, In: HAEMATOLOGICA. 109, 9, p. 3071-3077 7 p.

    Research output: SCORING: Contribution to journalCase reportResearchpeer-review

  3. Multiresistente Erreger – Sind sie auch resistent gegenüber Desinfektionsmitteln?

    Knobloch, J. & Knobling, B., 09.2024, In: DEUT MED WOCHENSCHR. 149, 19, p. 1151-1157 7 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  4. Gentamicin combination treatment is associated with lower mortality in patients with invasive listeriosis - a retrospective analysis

    Sutter, J. P., Kocheise, L., Kempski, J., Christner, M., Wichmann, D., Pinnschmidt, H., Schmiedel, S., Lohse, A. W., Huber, S. & Brehm, T. T., 08.2024, In: INFECTION. 52, 4, p. 1601-1606 6 p.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  5. Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling

    Ohnezeit, D., Huang, J., Westerkamp, U., Brinschwitz, V., Schmidt, C., Günther, T., Czech-Sioli, M., Weißelberg, S., Schlemeyer, T., Nakel, J., Mai, J., Schreiner, S., Schneider, C., Friedel, C. C., Schwanke, H., Brinkmann, M. M., Grundhoff, A. & Fischer, N., 08.2024, In: PLOS PATHOG. 20, 8, e1012426.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Multicenter benchmarking of short and long read wet lab protocols for clinical viral metagenomics

    Lopez-Labrador, F. X., Huber, M., Sidorov, I. A., Brown, J. R., Cuypers, L., Laenen, L., Vanmechelen, B., Maes, P., Fischer, N., Pichler, I., Storey, N., Atkinson, L., Schmutz, S., Kufner, V., van Boheemen, S., Mulders, C. E., Grundhoff, A., Blümke, P., Robitaille, A., Cinek, O., Hubáčková, K., Mourik, K., Boers, S. A., Stauber, L., Salmona, M., Cappy, P., Ramette, A., Franze', A., LeGoff, J., Claas, E. C. J., Rodriguez, C., de Vries, J. J. C. & European Society of Clinical Virology (ESCV) Network on Next-Generation Sequencing (ENNGS), 08.2024, In: J CLIN VIROL. 173, p. 105695

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. A multicenter study of asymmetric and symmetric dimethylarginine as predictors of mortality risk in hospitalized COVID-19 patients

    Hannemann, J., Zink, A., Mileva, Y., Balfanz, P., Dahl, E., Volland, S., Illig, T., Schwedhelm, E., Kurth, F., Stege, A., Aepfelbacher, M., Hoffmann, A. & Böger, R., 08.07.2024, In: SCI REP-UK. 14, 1, p. 15739

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Inefficient tissue immune response against MPXV in an immunocompromised mpox patient

    Matschke, J., Hartmann, K., Pfefferle, S., Wang, Y., Valdes, P. A., Thies, E., Schweizer, M., Lütgehetmann, M., Schmiedel, S., Bernreuther, C., Boyden, E. S., Glatzel, M. & Krasemann, S., 07.2024, In: J MED VIROL. 96, 7, p. e29811

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  9. Blocking viral entry with bulevirtide reduces the number of HDV-infected hepatocytes in human liver biopsies

    Allweiss, L., Volmari, A., Suri, V., Wallin, J. J., Flaherty, J. F., Manuilov, D., Downie, B., Lütgehetmann, M., Bockmann, J-H., Urban, S., Wedemeyer, H. & Dandri, M., 06.2024, In: J HEPATOL. 80, 6, p. 882-891 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Pilot study in Hamburg on the prevalence of SARS-CoV-2 infections and pandemic survey in the German funeral industry

    Schädler, J., Lütgehetmann, M., Schröder, A. S., Edler, C., Püschel, K., Ondruschka, B. & Fitzek, A., 06.2024, In: FORENSIC SCI MED PAT. 20, 2, p. 500-507 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Concordance between MITS and conventional autopsies for pathological and virological diagnoses

    Schädler, J., Azeke, A. T., Ondruschka, B., Steurer, S., Lütgehetmann, M., Fitzek, A. & Möbius, D., 03.2024, In: INT J LEGAL MED. 138, 2, p. 431-442 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Adaptation and validation of a quantitative vanA/vanB DNA screening assay on a high-throughput PCR system

    Giersch, K., Tanida, K., Both, A., Nörz, D., Heim, D., Rohde, H., Aepfelbacher, M. & Lütgehetmann, M., 12.02.2024, In: SCI REP-UK. 14, 1, p. 3523

    Research output: SCORING: Contribution to journalSCORING: Journal articleTransferpeer-review

  13. Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor

    Sake, S. M., Zhang, X., Rajak, M. K., Urbanek-Quaing, M., Carpentier, A., Gunesch, A. P., Grethe, C., Matthaei, A., Rückert, J., Galloux, M., Larcher, T., Le Goffic, R., Hontonnou, F., Chatterjee, A. K., Johnson, K., Morwood, K., Rox, K., Elgaher, W. A. M., Huang, J., Wetzke, M., Hansen, G., Fischer, N., Eléouët, J-F., Rameix-Welti, M-A., Hirsch, A. K. H., Herold, E., Empting, M., Lauber, C., Krey, T., Haid, S. & Pietschmann, T., 08.02.2024, In: NAT COMMUN. 15, 1, p. 1173

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Pharmacokinetic/pharmacodynamic evaluation of tigecycline dosing in a hollow fiber infection model against clinical bla-KPC producing Klebsiella Pneumoniae isolates

    Amann, L. F., Broeker, A., Riedner, M., Rohde, H., Huang, J., Nordmann, P., Decousser, J-W. & Wicha, S. G., 02.2024, In: DIAGN MICR INFEC DIS. 108, 2, p. 116153 116153.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. The added value of (1,3)-β-D-glucan for the diagnosis of Invasive Candidiasis in ICU patients: a prospective cohort study

    Christner, M., Abdennadher, B., Wichmann, D., Kluge, S., Pepić, A., Aepfelbacher, M., Rohde, H. & Olearo, F., 02.2024, In: INFECTION. 52, 1, p. 73-81 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Obesity and diabetes mellitus are associated with SARS-CoV-2 outcomes without influencing signature genes of extrapulmonary immune compartments at the RNA level

    Lücke, J., Böttcher, M., Nawrocki, M., Meins, N., Schnell, J., Heinrich, F., Bertram, F., Sabihi, M., Seeger, P., Pfaff, M., Notz, S., Blankenburg, T., Zhang, T., Kempski, J., Reeh, M., Wolter, S., Mann, O., Lütgehetmann, M., Hackert, T., Izbicki, J. R., Duprée, A., Huber, S., Ondruschka, B. & Giannou, A. D., 30.01.2024, In: HELIYON. 10, 2, p. e24508

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. High Genetic Diversity in Third-Generation Cephalosporin-Resistant Escherichia coli in Wastewater Systems of Schleswig-Holstein

    Carlsen, L., Grottker, M., Heim, M., Knobling, B., Schlauß, S., Wellbrock, K. & Knobloch, J. K., 20.01.2024, In: PATHOGENS. 13, 1, 90.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Matrix metalloproteinases at a glance

    Hey, S. & Linder, S., 15.01.2024, In: J CELL SCI. 137, 2, cs261898.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  19. Appeal from the European tuberculosis reference laboratory network (ERLTB-Net) for improving the diagnosis of infections due to nontuberculous mycobacteria

    Tagliani, E., Kohl, T. A., Ghodousi, A., Groenheit, R., Holicka, Y., Niemann, S., Maurer, F. P., Cirillo, D. M. & Cambau, E., 01.2024, In: CLIN MICROBIOL INFEC. 30, 1, p. 4-6 3 p.

    Research output: SCORING: Contribution to journalComment/debateResearch

  20. Immune responses and clinical outcomes after COVID-19 vaccination in patients with liver disease and liver transplant recipients

    Murray, S. M., Pose, E., Wittner, M., Londoño, M-C., Schaub, G., Cook, J., Dimitriadis, S., Meacham, G., Irwin, S., Lim, Z., Duengelhoef, P., Sterneck, M., Lohse, A. W., Perez, V., Trivedi, P., Bhandal, K., Mullish, B. H., Manousou, P., Provine, N. M., Avitabile, E., Carroll, M., Tipton, T., Healy, S., Burra, P., Klenerman, P., Dunachie, S., Kronsteiner, B., Maciola, A. K., Pasqual, G., Hernandez-Gea, V., Garcia-Pagan, J. C., Lampertico, P., Iavarone, M., Gines, P., Lütgehetmann, M., Schulze Zur Wiesch, J., Russo, F. P., Barnes, E., Marjot, T. & OCTAVE Collaborative Group, PITCH study, and the EASL supported COVID-Hep vaccine network, 01.2024, In: J HEPATOL. 80, 1, p. 109-123 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Therapie bei MDR-, prä-XDR-, XDR-Tuberkulose und Rifampicin-Resistenz oder bei Medikamentenunverträglichkeit gegenüber mindestens Rifampicin

    Otto-Knapp, R., Bauer, T., Brinkmann, F., Feiterna-Sperling, C., Friesen, I., Geerdes-Fenge, H., Hartmann, P., Häcker, B., Hauer, B., Haas, W., Heyckendorf, J., Kuhns, M., Lange, C., Maurer, F. P., Nienhaus, A., Priwitzer, M., Richter, E., Salzer, H. J. F., Schoch, O., Schönfeld, N. & Schaberg, T., 01.2024, In: PNEUMOLOGIE. 78, 1, p. 35-46 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Do asymptomatic STEC-long-term carriers need to be isolated or decolonized? New evidence from a community case study and concepts in favor of an individualized strategy

    Sayk, F., Hauswaldt, S., Knobloch, J. K., Rupp, J. & Nitschke, M., 2024, In: FRONT PUBLIC HEALTH. 12, p. 1364664

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Immunity against measles, mumps, rubella, and varicella among homeless individuals in Germany - A nationwide multi-center cross-sectional study

    Graf, W., Bertram, F., Dost, K. M., Brennecke, A., Kowalski, V., van Rüth, V., Nörz, D. S., Wulff, B., Ondruschka, B., Püschel, K., Pfefferle, S., Lütgehetmann, M. & Heinrich, F., 2024, In: FRONT PUBLIC HEALTH. 12, p. 1375151 1375151.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. 2023
  25. Stenotrophomonas maltophilia affects the gene expression profiles of the major pathogens Pseudomonas aeruginosa and Staphylococcus aureus in an in vitro multispecies biofilm model

    Alio, I., Moll, R., Hoffmann, T., Mamat, U., Schaible, U. E., Pappenfort, K., Alawi, M., Schie, M., Thünauer, R., Stamm, J., Rohde, H. & Streit, W. R., 12.12.2023, In: MICROBIOL SPECTR. 11, 6, e0085923.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. A bacterial effector protein promotes nuclear translocation of Stat3 to induce IL-10.

    Berneking, L., Bekere, I., Rob, S., Schnapp, M., Huang, J., Ruckdeschel, K. & Aepfelbacher, M., 12.2023, In: EUR J CELL BIOL. 102, 4, p. 151364 151364.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Get a grip: Podosomes as potential players in phagocytosis

    Linder, S. & Barcelona, B., 12.2023, In: EUR J CELL BIOL. 102, 4, 151356.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. KIF16B drives MT1-MMP recycling in macrophages and promotes co-invasion of cancer cells

    Hey, S., Wiesner, C., Barcelona, B. & Linder, S., 11.2023, In: LIFE SCI ALLIANCE. 6, 11, e202302158.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Potent broadly neutralizing antibody VIR-3434 controls hepatitis B and D virus infection and reduces HBsAg in humanized mice

    Lempp, F. A., Volz, T., Cameroni, E., Benigni, F., Zhou, J., Rosen, L. E., Noack, J., Zatta, F., Kaiser, H., Bianchi, S., Lombardo, G., Jaconi, S., Vincenzetti, L., Imam, H., Soriaga, L. B., Passini, N., Belnap, D. M., Schulze, A., Lütgehetmann, M., Telenti, A., Cathcart, A. L., Snell, G., Purcell, L. A., Hebner, C. M., Urban, S., Dandri, M., Corti, D. & Schmid, M. A., 11.2023, In: J HEPATOL. 79, 5, p. 1129-1138 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Activity of antimicrobial examination gloves under realistic conditions:challenge not fulfilled

    Klupp, E-M., Knobling, B., Franke, G., Belmar Campos, C., Maurer, P. M. & Knobloch, J. K., 24.10.2023, In: ANTIMICROB RESIST IN. 12, 1, 116.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  31. Complete genome sequence of a Staphylococcus condimenti isolated from a port catheter-associated bloodstream infection

    Berneking, L., Büttner, H., Qi, M., Günther, T., Lehnhoff, D., Both, A., Christner, M., Wolters, M., Alawi, M., Aepfelbacher, M. & Rohde, H., 19.10.2023, In: MICROBIOL RESOUR ANN. 12, 10, 3 p., e0043823.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  32. Increased local bone turnover in patients with chronic periprosthetic joint infection

    Hinz, N., Butscheidt, S., Jandl, N. M., Rohde, H., Keller, J., Beil, F. T., Hubert, J. & Rolvien, T., 10.10.2023, In: BONE JOINT RES. 12, 10, p. 644-653 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. High burden of RSV and influenza in patients presenting with suspected pneumonia in the emergency room of a German tertiary hospital in fall of 2022

    Ettemeyer, M., Florey, M., Tanida, K., Jochum, J., Schulze-Sturm, U., Lütgehetmann, M., Baehr, M., Addo, M. M., Schmiedel, S., Rohde, H. & Koch, T., 10.2023, In: INFECTION. 51, 5, p. 1569-1575 7 p.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  34. Superiority of manual disinfection using pre-soaked wipes over automatic UV-C radiation without prior cleaning

    Knobling, B., Ulatowski, A., Franke, G., Belmar Campos, C., Büttner, H., Klupp, E. M., Maurer, P. M., Brill, F. H. H. & Knobloch, J. K., 10.2023, In: J HOSP INFECT. 140, p. 72-78 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Tecovirimat for the treatment of severe Mpox in Germany

    Hermanussen, L., Brehm, T. T., Wolf, T., Boesecke, C., Schlabe, S., Borgans, F., Monin, M. B., Jensen, B-E. O., Windhaber, S., Scholten, S., Jordan, S., Lütgehetmann, M., Wiesch, J. S. Z., Addo, M. M., Mikolajewska, A., Niebank, M. & Schmiedel, S., 10.2023, In: INFECTION. 51, 5, p. 1563-1568 6 p.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  36. Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection

    Lücke, J., Heinrich, F., Malsy, J., Meins, N., Schnell, J., Böttcher, M., Nawrocki, M., Zhang, T., Bertram, F., Sabihi, M., Kempski, J., Blankenburg, T., Duprée, A., Reeh, M., Wolter, S., Mann, O., Izbicki, J. R., Lohse, A. W., Gagliani, N., Lütgehetmann, M., Bunders, M. J., Altfeld, M., Sauter, G., Giannou, A. D., Krasemann, S., Ondruschka, B. & Huber, S., 15.09.2023, In: J IMMUNOL. 211, 6, p. 1052-1061 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. CHROMAgar™ LIN-R as an efficient screening tool to assess the prevalence of linezolid-resistant enterococci in German hospital patients-a multicentre study approach, 2021-2022

    Bender, J. K., Baufeld, E., Becker, K., Claus, H., Dudakova, A., Dörre, A., Fila, N., Fleige, C., Hamprecht, A., Hoffmann, A., Hogardt, M., Kaasch, A. J., Kola, A., Kriebel, N., Layer-Nicolaou, F., Marschal, M., Molitor, E., Mutters, N. T., Liese, J., Nelkenbrecher, C., Neumann, B., Rohde, H., Steinmann, J., Sörensen, M., Thelen, P., Weig, M., Zautner, A. E. & Werner, G., 05.09.2023, In: J ANTIMICROB CHEMOTH. 78, 9, p. 2185-2191 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Evaluation of a Quantitative Dual-Target EBV DNA Test on a Fully Automated Molecular Testing System

    Lütgehetmann, M., Albert, E., Hamilton, A., Jarem, D., Pfefferle, S., Stucki, H. & Navarro, D., 23.08.2023, In: Journal of Clinical Microbiology. 61, 8, e0051823.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Performance and Hypothetical Impact on Joint Infection Management of the BioFire Joint Infection Panel: a Retrospective Analysis

    Berinson, B., Spenke, L., Krivec, L., Tanida, K., Both, A., Keller, J., Rolvien, T., Christner, M., Lütgehetmann, M., Aepfelbacher, M., Klatte, T. O. & Rohde, H., 23.08.2023, In: Journal of Clinical Microbiology. 61, 8, e0059223.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Long time persistence and evolution of carbapenemase-producing Enterobacterales in the wastewater of a tertiary care hospital in Germany

    Carlsen, L., Büttner, H., Christner, M., Cordts, L., Franke, G., Hoffmann, A., Knobling, B., Lütgehetmann, M., Nakel, J., Werner, T. & Knobloch, J. K., 08.2023, In: J INFECT PUBLIC HEAL. 16, 8, p. 1142-1148 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Screening for Resistant Bacteria, Antimicrobial Resistance Genes, Sexually Transmitted Infections and Schistosoma spp. in Tissue Samples from Predominantly Vaginally Delivered Placentae in Ivory Coast and Ghana

    Franz, R., Hahn, A., Hagen, R. M., Rohde, H., Eberhardt, K. A., Ehrhardt, S., Baum, J., Claussen, L., Feldt, T., Hinz, R., Barthel, D., Bindt, C., Tagbor, H., Nguah, S. B., Koffi, M., Köller, T., Warnke, P., Pankok, F., Taudien, S., Frickmann, H. & Schoppen, S., 30.07.2023, In: PATHOGENS. 12, 8, 999.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Novel Synergies and Isolate Specificities in the Drug Interaction Landscape of Mycobacterium abscessus

    Van, N., Degefu, Y. N., Leus, P. A., Larkins-Ford, J., Klickstein, J., Maurer, F. P., Stone, D., Poonawala, H., Thorpe, C. M., Smith, T. C. & Aldridge, B. B., 18.07.2023, In: ANTIMICROB AGENTS CH. 67, 7, p. e00090-23

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Reduced Humoral and Cellular Immune Response to Primary COVID-19 mRNA Vaccination in Kidney Transplanted Children Aged 5–11 Years

    Lalia, J. K., Schild, R-S., Lütgehetmann, M., Dunay, G. A., Kallinich, T., Kobbe, R., Massoud, M., Oh, J., Pietzsch, L., Schulze-Sturm, U., Schuetz, C., Sibbertsen, F., Speth, F., Thieme, S., Witkowski, M., Berner, R., Muntau, A. C., Gersting, S. W., Toepfner, N., Pagel, J. & Paul, K., 14.07.2023, In: VIRUSES-BASEL. 15, 7, p. 1553

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Epidemiology of co-infections in pregnant women living with human immunodeficiency virus 1 in rural Gabon: a cross-sectional study

    Davi, S. D., Okwu, D. G., Luetgehetmann, M., Abba, F. M., Aepfelbacher, M., Endamne, L. R., Alabi, A., Zoleko-Manego, R., Mombo-Ngoma, G., Mahmoudou, S., Addo, M. M., Ramharter, M. & Mischlinger, J., 06.07.2023, In: INFECT DIS POVERTY. 12, 1, 64.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

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