Institute of Medical Microbiology, Virology and Hygiene

Publications

  1. 2022
  2. There and back again: Intracellular trafficking, release and recycling of matrix metalloproteinases

    Hey, S., Ratt, A. & Linder, S., 04.2022, In: BBA-MOL CELL RES. 1869, 4, 119189.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  3. Intracranial hemorrhage in COVID-19 patients during extracorporeal membrane oxygenation for acute respiratory failure: a nationwide register study report

    von Stillfried, S., Bülow, R. D., Röhrig, R., Meybohm, P., Boor, P. & German Registry of COVID-19 Autopsies (DeRegCOVID), DeRegCOVID Collaborators, 28.03.2022, In: CRIT CARE. 26, 1, 83.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. The Transcription Factor SpoVG Is of Major Importance for Biofilm Formation of Staphylococcus epidermidis under In Vitro Conditions, but Dispensable for In Vivo Biofilm Formation

    Benthien, H., Fresenborg, B., Pätzold, L., Elhawy, M. I., Huc-Brandt, S., Beisswenger, C., Krasteva-Christ, G., Becker, S. L., Molle, V., Knobloch, J. K. & Bischoff, M., 17.03.2022, In: INT J MOL SCI. 23, 6, 3255.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Variants

    Nörz, D., Grunwald, M., Tang, H. T., Weinschenk, C., Günther, T., Robitaille, A., Giersch, K., Fischer, N., Grundhoff, A., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M., 15.03.2022, In: VIRUSES-BASEL. 14, 3, 608.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Infant immunity against viral infections is advanced by the placenta-dependent vertical transfer of maternal antibodies

    Albrecht, M., Pagenkemper, M., Wiessner, C., Spohn, M., Lütgehetmann, M., Jacobsen, H., Gabriel, G., Zazara-Giannou, D. E., Haertel, C., Hecher, K., Diemert, A. & Arck, P. C., 08.03.2022, In: VACCINE. 40, 11, p. 1563-1571 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Comparing susceptibility and contagiousness in concurrent outbreaks with a non-VOC and the VOC SARS-CoV-2 variant B.1.1.7 in daycare centers in Hamburg, Germany

    Nakel, J., Robitaille, A., Günther, T., Rosenau, L., Czech-Sioli, M., Plenge-Bönig, A., Bühler, S., Wille, A., Jakubowski, E., Pruskil, S., Wahlen, M., Indenbirken, D., Nörz, D., Lütgehetmann, M., Aepfelbacher, M., Grundhoff, A., Grolle, B. & Fischer, N., 03.2022, In: INT J HYG ENVIR HEAL. 240, 113928.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Evaluation of a syndromic panel polymerase chain reaction (spPCR) assay for the diagnosis of device associated bone and joint infections (BJI)

    Berneking, L., Haas, M., Frielinghaus, L., Berinson, B., Lütgehetmann, M., Christner, M., Aepfelbacher, M., Gerlach, U., Seide, K., Both, A. & Rohde, H., 03.2022, In: INT J INFECT DIS. 116, p. 283-288 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Molecular consequences of SARS-CoV-2 liver tropism

    Wanner, N., Andrieux, G., Badia-I-Mompel, P., Edler, C., Pfefferle, S., Lindenmeyer, M. T., Schmidt-Lauber, C., Czogalla, J., Wong, M. N., Okabayashi, Y., Braun, F., Lütgehetmann, M., Meister, E., Lu, S., Noriega, M. L. M., Günther, T., Grundhoff, A., Fischer, N., Bräuninger, H., Lindner, D., Westermann, D., Haas, F., Roedl, K., Kluge, S., Addo, M. M., Huber, S., Lohse, A. W., Reiser, J., Ondruschka, B., Sperhake, J. P., Saez-Rodriguez, J., Boerries, M., Hayek, S. S., Aepfelbacher, M., Scaturro, P., Puelles, V. G. & Huber, T. B., 03.2022, In: NAT METAB. 4, 3, p. 310-319 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Necrotizing Soft Tissue Infections in Intensive Care

    Ogica, A., Burdelski, C., Rohde, H., Kluge, S. & de Heer, G., 03.2022, In: J INTENSIVE CARE MED. 37, 3, p. 393-400 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Population dynamics in colonizing vancomycin-resistant Enterococcus faecium isolated from immunosuppressed patients

    Both, A., Kruse, F., Mirwald, N., Franke, G., Christner, M., Huang, J., Hansen, J. L., Kröger, N., Berneking, L., Lellek, H., Aepfelbacher, M. & Rohde, H., 03.2022, In: J GLOB ANTIMICROB RE. 28, p. 267-273 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Involvement of the Iron-Regulated Loci hts and fhuC in Biofilm Formation and Survival of Staphylococcus epidermidis within the Host

    Oliveira, F., Lima, T., Correia, A., Silva, A. M., Soares, C., Morais, S., Weißelberg, S., Vilanova, M., Rohde, H. & Cerca, N., 23.02.2022, In: MICROBIOL SPECTR. 10, 1, e0216821.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

    Krasemann, S., Haferkamp, U., Pfefferle, S., Woo, M. S., Heinrich, F., Schweizer, M., Appelt-Menzel, A., Cubukova, A., Barenberg, J., Leu, J., Hartmann, K., Thies, E., Littau, J. L., Sepulveda-Falla, D., Zhang, L., Ton, K., Liang, Y., Matschke, J., Ricklefs, F., Sauvigny, T., Sperhake, J., Fitzek, A., Gerhartl, A., Brachner, A., Geiger, N., König, E-M., Bodem, J., Franzenburg, S., Franke, A., Moese, S., Müller, F-J., Geisslinger, G., Claussen, C., Kannt, A., Zaliani, A., Gribbon, P., Ondruschka, B., Neuhaus, W., Friese, M. A., Glatzel, M. & Pless, O., 08.02.2022, In: STEM CELL REP. 17, 2, p. 307-320 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Markers of neutrophil activation and extracellular trap formation predict appendicitis

    Boettcher, M., Schacker, A-L., Esser, M., Schönfeld, L., Ebenebe, C. U., Rohde, H., Mokhaberi, N., Trochimiuk, M., Appl, B., Raluy, L. P., Reinshagen, K., Klohs, S. & Königs, I., 02.2022, In: SURGERY. 171, 2, p. 312-319 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo

    Allweiss, L., Giersch, K., Pirosu, A., Volz, T., Muench, R. C., Beran, R. K., Urban, S., Javanbakht, H., Fletcher, S. P., Lütgehetmann, M. & Dandri-Petersen, M., 02.2022, In: GUT. 71, 2, p. 372-381 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Efficacy of Tigecycline as Salvage Therapy in Multidrug-Resistant Febrile Neutropenia in Patients with Acute Leukemia-A Single Center Analysis

    Modemann, F., Härterich, S., Schulze Zur Wiesch, J., Rohde, H., Lindeman, N. B., Bokemeyer, C., Fiedler, W. & Ghandili, S., 19.01.2022, In: ANTIBIOTICS-BASEL. 11, 2, 128.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. In the Search of Marine Pestiviruses:First Case of Phocoena Pestivirus in a Belt Sea Harbour Porpoise

    Stokholm, I., Fischer, N., Baechlein, C., Postel, A., Galatius, A., Kyhn, L. A., Thøstesen, C. B., Persson, S., Siebert, U., Olsen, M. T. & Becher, P., 17.01.2022, In: VIRUSES-BASEL. 14, 1, 161.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Correction: Broadly directed SARS-CoV-2-specific CD4+ T cell response includes frequently detected peptide specificities within the membrane and nucleoprotein in patients with acute and resolved COVID-19

    Heide, J., Schulte, S., Kohsar, M., Brehm, T. T., Herrmann, M., Karsten, H., Marget, M., Peine, S., Johansson, A. M., Sette, A., Lütgehetmann, M., Kwok, W. W., Sidney, J. & Schulze Zur Wiesch, J., 01.2022, In: PLOS PATHOG. 18, 1, e1010220.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  19. Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant

    Heinrich, F., Romich, C., Zimmermann, T., Kniep, I., Fitzek, A., Steurer, S., Glatzel, M., Nörz, D., Günther, T., Czech-Sioli, M., Fischer, N., Grundhoff, A., Lütgehetmann, M. & Ondruschka, B., 01.2022, In: INT J LEGAL MED. 136, 1, p. 193-202 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Impact of single-room contact precautions on acquisition and transmission of vancomycin-resistant enterococci on haematological and oncological wards, multicentre cohort-study, Germany, January-December 2016

    Biehl, L. M., Higgins, P. G., Stemler, J., Gilles, M., Peter, S., Dörfel, D., Vogel, W., Kern, W. V., Gölz, H., Bertz, H., Rohde, H., Klupp, E-M., Schafhausen, P., Salmanton-García, J., Stecher, M., Wille, J., Liss, B., Xanthopoulou, K., Zweigner, J., Seifert, H. & Vehreschild, M. J. G. T., 01.2022, In: EUROSURVEILLANCE. 27, 2, 2001876.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths

    Heinrich, F., Schröder, A. S., Gerberding, A-L., Gerling, M., Langenwalder, F., Lange, P., Heinemann, A., Bibiza-Freiwald, E., Nörz, D. S., Aepfelbacher, M., Pfefferle, S., Ondruschka, B. & Lütgehetmann, M., 01.2022, In: EMERG INFECT DIS. 28, 1, p. 244-247 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  22. Risk of transfusion-transmitted hepatitis E virus infection from pool-tested platelets and plasma

    Cordes, A. K., Goudeva, L., Lütgehetmann, M., Wenzel, J. J., Behrendt, P., Wedemeyer, H. & Heim, A., 01.2022, In: J HEPATOL. 76, 1, p. 46-52 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. SARS-CoV2-specific humoral and T-cell immune response after second vaccination in liver cirrhosis and transplant patients

    Ruether, D. F., Schaub, G. M., Duengelhoef, P. M., Haag, F., Brehm, T. T., Fathi, A., Wehmeyer, M., Jahnke-Triankowski, J., Mayer, L., Hoffmann, A., Fischer, L., Addo, M. M., Lütgehetmann, M., Lohse, A. W., Schulze Zur Wiesch, J. & Sterneck, M., 01.2022, In: CLIN GASTROENTEROL H. 20, 1, p. 162-172.e9

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Development of an artificial synovial fluid useful for studying Staphylococcus epidermidis joint infections

    Stamm, J., Weißelberg, S., Both, A., Failla, A. V., Nordholt, G., Büttner, H., Linder, S., Aepfelbacher, M. & Rohde, H., 2022, In: FRONT CELL INFECT MI. 12, 948151.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. High-resolution analysis of individual spike peptide-specific CD4+ T-cell responses in vaccine recipients and COVID-19 patients

    Karsten, H., Cords, L., Westphal, T., Knapp, M., Brehm, T. T., Hermanussen, L., Omansen, T. F., Schmiedel, S., Woost, R., Ditt, V., Peine, S., Lütgehetmann, M., Huber, S., Ackermann, C., Wittner, M., Addo, M. M., Sette, A., Sidney, J. & Schulze Zur Wiesch, J., 2022, In: CLIN TRANSL IMMUNOL. 11, 8, e1410.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Lack of Evidence of Hepatitis E Virus Infections in a Cohort of Boars and Deer Species in a Game Reserve in Northern Germany

    Westphal, T., Delling, M., Mader, M., Ackermann, C., Horvatits, T., Lütgehetmann, M., Schulze zur Wiesch, J., Pischke, S. & Beisel, C., 2022, In: Zoonotic Diseases. 2, 4, p. 228-233

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. The Staphylococcus epidermidis Transcriptional Profile During Carriage

    Teichmann, P., Both, A., Wolz, C., Hornef, M. W., Rohde, H., Yazdi, A. S. & Burian, M., 2022, In: FRONT MICROBIOL. 13, 896311.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Young COVID-19 Patients Show a Higher Degree of Microglial Activation When Compared to Controls

    Matschke, J., Lahann, H., Krasemann, S., Altmeppen, H., Pfefferle, S., Galliciotti, G., Fitzek, A., Sperhake, J-P., Ondruschka, B., Busch, M., Rotermund, N., Schulz, K., Lohr, C., Dottermusch, M. & Glatzel, M., 2022, In: FRONT NEUROL. 13, 908081.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. 2021
  30. Aspergillosis: emerging risk groups in critically ill patients

    Kluge, S., Strauß, R., Kochanek, M., Weigand, M. A., Rohde, H. & Lahmer, T., 08.12.2021, In: MED MYCOL. 60, 1, myab064.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  31. Clinical establishment of a laboratory developed quantitative HDV PCR assay on the cobas6800 high-throughput system

    Pflüger, L. S., Nörz, D., Volz, T., Giersch, K., Giese, A., Goldmann, N., Glebe, D., Bockmann, J-H., Pfefferle, S., Dandri, M., Schulze Zur Wiesch, J. & Lütgehetmann, M., 12.2021, In: JHEP REP. 3, 6, 100356.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Multicenter Evaluation of a Fully Automated High-Throughput SARS-CoV-2 Antigen Immunoassay

    Nörz, D., Olearo, F., Perisic, S., Bauer, M. F., Riester, E., Schneider, T., Schönfeld, K., Laengin, T. & Lütgehetmann, M., 12.2021, In: INFECT DIS THER. 10, 4, p. 2371-2379 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Polymicrobial enteric infections in african infants with diarrhoea - Results from a longitudinal prospective case-control study

    Heinemann, M., Strauchs, C., Lütgehetmann, M., Aepfelbacher, M., Klupp, E-M., Owusu-Dabo, E., Rolling, T., Cramer, J. P. & Vinnemeier, C. D., 12.2021, In: CLIN MICROBIOL INFEC. 27, 12, p. 1792-1798 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Real time, in-line optical mapping of single molecules of DNA

    Esmek, F. M., Erichlandwehr, T., Mors, D. H. B., Czech-Sioli, M., Therre, M., Günther, T., Grundhoff, A., Fischer, N. & Fernandez-Cuesta, I., 12.2021, In: Biosensors and Bioelectronics: X. 9, 100087.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Nectin stabilization at adherens junctions is counteracted by Rab5a-dependent endocytosis

    Cervero, P., Vrenken, K., Klose, M., Rehm, K. & Linder, S., 27.11.2021, In: EUR J CELL BIOL. 100, 7-8, 151184.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Multiorgan tropism of SARS-CoV-2 lineage B.1.1.7

    Ondruschka, B., Heinrich, F., Lindenmeyer, M., Edler, C., Möbius, D., Czogalla, J., Heinemann, A., Braun, F., Aepfelbacher, M., Lütgehetmann, M. & Huber, T. B., 11.2021, In: INT J LEGAL MED. 135, 6, p. 2347-2349 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Rätselhafte B-Symptomatik bei einem 61-Jährigen unter Therapie einer rheumatoiden Arthritis

    Wüstenberg, R., Christner, M., Schmiedel, S., Tariparast, A., Wichmann, D., Lennartz, M., Klose, H. & Kluge, S., 11.2021, In: INTERNIST. 62, 11, p. 1231-1236 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

    Wenzel, J., Lampe, J., Müller-Fielitz, H., Schuster, R., Zille, M., Müller, K., Krohn, M., Körbelin, J., Zhang, L., Özorhan, Ü., Neve, V., Wagner, J. U. G., Bojkova, D., Shumliakivska, M., Jiang, Y., Fähnrich, A., Ott, F., Sencio, V., Robil, C., Pfefferle, S., Sauve, F., Coêlho, C. F. F., Franz, J., Spiecker, F., Lembrich, B., Binder, S., Feller, N., König, P., Busch, H., Collin, L., Villaseñor, R., Jöhren, O., Altmeppen, H. C., Pasparakis, M., Dimmeler, S., Cinatl, J., Püschel, K., Zelic, M., Ofengeim, D., Stadelmann, C., Trottein, F., Nogueiras, R., Hilgenfeld, R., Glatzel, M., Prevot, V. & Schwaninger, M., 11.2021, In: NAT NEUROSCI. 24, 11, p. 1522-1533 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Yersinia remodels epigenetic histone modifications in human macrophages

    Bekere, I., Huang, J., Schnapp, M., Rudolph, M., Berneking, L., Ruckdeschel, K., Grundhoff, A., Günther, T., Fischer, N. & Aepfelbacher, M., 11.2021, In: PLOS PATHOG. 17, 11, e1010074.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Molecular Epidemiology of Carbapenem-Resistant Acinetobacter baumannii Strains Isolated at the German Military Field Laboratory in Mazar-e Sharif, Afghanistan

    Higgins, P. G., Kniel, M., Rojak, S., Balczun, C., Rohde, H., Frickmann, H. & Hagen, R. M., 26.10.2021, In: MICROORGANISMS. 9, 11, 2229.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Contamination of multi dose eyedrops in the intra and perioperative context

    Daehn, T., Schneider, A., Knobloch, J., Hellwinkel, O. J. C., Spitzer, M. S. & Kromer, R., 13.10.2021, In: SCI REP-UK. 11, 1, 20364.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Rapid Automated Screening for SARS-CoV-2 B.1.617 Lineage Variants (Delta/Kappa) through a Versatile Toolset of qPCR-Based SNP Detection

    Nörz, D., Grunwald, M., Tang, H. T., Olearo, F., Günther, T., Robitaille, A., Fischer, N., Grundhoff, A., Aepfelbacher, M., Pfefferle, S. & Lütgehetmann, M., 01.10.2021, In: DIAGNOSTICS. 11, 10, 1818.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. A resampling strategy for studying robustness in virus detection pipelines

    Kohls, M., Saremi, B., Muchsin, I., Fischer, N., Becher, P. & Jung, K., 10.2021, In: COMPUT BIOL CHEM. 94, 107555.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis

    Moreno-Layseca, P., Jäntti, N. Z., Godbole, R., Sommer, C., Jacquemet, G., Al-Akhrass, H., Conway, J. R. W., Kronqvist, P., Kallionpää, R. E., Oliveira-Ferrer, L., Cervero, P., Linder, S., Aepfelbacher, M., Zauber, H., Rae, J., Parton, R. G., Disanza, A., Scita, G., Mayor, S., Selbach, M., Veltel, S. & Ivaska, J., 10.2021, In: NAT CELL BIOL. 23, 10, p. 1073-1084 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Heatwave-associated Vibrio infections in Germany, 2018 and 2019

    Brehm, T. T., Berneking, L., Sena Martins, M., Dupke, S., Jacob, D., Drechsel, O., Bohnert, J., Becker, K., Kramer, A., Christner, M., Aepfelbacher, M., Schmiedel, S., Rohde, H. & German Vibrio Study Group, 10.2021, In: EUROSURVEILLANCE. 26, 41, p. 2002041

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Influence of microbiological diagnosis on the clinical course of spondylodiscitis

    Stangenberg, M., Mende, K. C., Mohme, M., Krätzig, T., Viezens, L., Both, A., Rohde, H. & Dreimann, M., 10.2021, In: INFECTION. 49, 5, p. 1017-1027 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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