III. Department of Medicine
Publications
- 2017
Expression and genetic polymorphism of necroptosis related protein RIPK1 is correlated with severe hepatic ischemia-reperfusion injury and prognosis after hepatectomy in hepatocellular carcinoma patients
Yao, C., Li, G., Cai, M., Qian, Y., Wang, L., Xiao, L., Thaiss, F. & Shi, B., 19.07.2017, In: CANCER BIOMARK. 20, 1, p. 23-29 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
From genetics to personalized nephrology: kidney research at a tipping point
Huber, T. B. & Holthofer, H., 07.2017, In: CELL TISSUE RES. 369, 1, p. 1-4Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis
Riedel, J-H., Becker, M., Kopp, K., Düster, M., Brix, S. R., Meyer-Schwesinger, C., Kluth, L. A., Gnirck, A-C., Attar, M., Krohn, S., Fehse, B., Stahl, R. A. K., Panzer, U. & Turner, J-E., 07.2017, In: J AM SOC NEPHROL. 28, 7, p. 2068-2080Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
New structural insights into podocyte biology
Grahammer, F., 07.2017, In: CELL TISSUE RES. 369, 1, p. 5-10 6 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice
Krones, E., Eller, K., Pollheimer, M. J., Racedo, S., Kirsch, A. H., Frauscher, B., Wahlström, A., Ståhlman, M., Trauner, M., Grahammer, F., Huber, T. B., Wagner, K., Rosenkranz, A. R., Marschall, H-U. & Fickert, P., 07.2017, In: J HEPATOL. 67, 1, p. 110-119 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Surgical treatment and outcome of TSH-producing pituitary adenomas
Rotermund, R., Riedel, N., Burkhardt, T., Matschke, J., Schmidt, N-O., Aberle, J. & Flitsch, J., 07.2017, In: ACTA NEUROCHIR. 159, 7, p. 1219-1226Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting mTOR Signaling Can Prevent the Progression of FSGS
Zschiedrich, S., Bork, T., Liang, W., Wanner, N., Eulenbruch, K., Munder, S., Hartleben, B., Kretz, O., Gerber, S., Simons, M., Viau, A., Burtin, M., Wei, C., Reiser, J., Herbach, N., Rastaldi, M-P., Cohen, C. D., Tharaux, P-L., Terzi, F., Walz, G., Gödel, M. & Huber, T. B., 07.2017, In: J AM SOC NEPHROL. 28, 7, p. 2144-2157 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Composition of the cellular infiltrate in patients with simple and complex appendicitis
Gorter, R. R., Wassenaar, E. C. E., de Boer, O. J., Bakx, R., Roelofs, J. J. T. H., Bunders, M. J., van Heurn, L. W. E. & Heij, H. A., 15.06.2017, In: J SURG RES. 214, p. 190-196 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier
Schell, C., Rogg, M., Suhm, M., Helmstädter, M., Sellung, D., Yasuda-Yamahara, M., Kretz, O., Küttner, V., Suleiman, H., Kollipara, L., Zahedi, R. P., Sickmann, A., Eimer, S., Shaw, A. S., Kramer-Zucker, A. G., Hirano-Kobayashi, M., Abe, T., Aizawa, S., Grahammer, F., Hartleben, B., Dengjel, J. & Huber, T. B., 06.06.2017, In: P NATL ACAD SCI USA. 114, 23, p. E4621-E4630Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes
Koehler, S., Brähler, S., Braun, F., Hagmann, H., Rinschen, M. M., Späth, M. R., Höhne, M., Wunderlich, F. T., Schermer, B., Benzing, T. & Brinkkoetter, P. T., 06.2017, In: KIDNEY INT. 91, 6, p. 1510-1517 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
New Insights into Podocyte Biology in Glomerular Health and Disease
Assady, S., Wanner, N., Skorecki, K. L. & Huber, T. B., 06.2017, In: J AM SOC NEPHROL. 28, 6, p. 1707-1715 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prostate cancer downregulated SIRP-α modulates apoptosis and proliferation through p38-MAPK/NF-κB/COX-2 signaling
Yao, C., Li, G., Cai, M., Qian, Y., Wang, L., Xiao, L., Thaiss, F. & Shi, B., 06.2017, In: ONCOL LETT. 13, 6, p. 4995-5001 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative comparison of human intestinal mononuclear leukocyte isolation techniques for flow cytometric analyses
Schreurs, R. R. C. E., Drewniak, A., Bakx, R., Corpeleijn, W. E., Geijtenbeek, T. H. B., van Goudoever, J. B. & Bunders, M. J., 06.2017, In: J IMMUNOL METHODS. 445, p. 45-52 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison between Minimally Invasive Surgery and Conventional Open Surgery for Patients with Spinal Metastasis: A Prospective Propensity Score-Matched Study
Hansen-Algenstaedt, N., Kwan, M. K., Algenstaedt, P., Chiu, C. K., Viezens, L., Chan, T. S., Lee, C. K., Wellbrock, J., Chan, C. Y. W. & Schaefer, C., 15.05.2017, In: SPINE. 42, 10, p. 789-797Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis
König, C., Braune, S., Roberts, J. A., Nierhaus, A., Steinmetz, O. M., Baehr, M., Frey, O. R., Langebrake, C. & Kluge, S., 01.05.2017, In: J ANTIMICROB CHEMOTH. 72, 5, p. 1433-1440Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Akutes Nierenversagen bei einer 75-jährigen Patientin mit High-output-Ileostoma
Teege, S., Wiech, T. & Steinmetz, O. M., 05.2017, In: INTERNIST. 58, 5, p. 507-511Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The long journey through renal Filtration: new pieces in the puzzle of slit diaphragm architecture
Conti, S., Perico, L., Grahammer, F. & Huber, T. B., 05.2017, In: CURR OPIN NEPHROL HY. 26, 3, p. 148-153 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts
Harrach, S., Edemir, B., Schmidt-Lauber, C., Pap, T., Bertrand, J. & Ciarimboli, G., 28.04.2017, In: SCI REP-UK. 7, 1, p. 1258Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
Bartelt, A., John, C., Schaltenberg, N., Berbée, J. F. P., Worthmann, A., Cherradi, M. L., Schlein, C., Piepenburg, J., Boon, M. R., Rinninger, F., Heine, M., Toedter, K., Niemeier, A., Nilsson, S. K., Fischer, M., Wijers, S. L., van Marken Lichtenbelt, W. D., Scheja, L., Rensen, P. C. N. & Heeren, J., 19.04.2017, In: NAT COMMUN. 8, p. Art. 15010Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
YAP-mediated mechanotransduction determines the podocyte's response to damage
Rinschen, M. M., Grahammer, F., Hoppe, A-K., Kohli, P., Hagmann, H., Kretz, O., Bertsch, S., Höhne, M., Göbel, H., Bartram, M. P., Gandhirajan, R. K., Krüger, M., Brinkkoetter, P. T., Huber, T. B., Kann, M., Wickström, S. A., Benzing, T. & Schermer, B., 11.04.2017, In: SCI SIGNAL. 10, 474Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RORγt expression in Tregs promotes systemic lupus erythematosus via IL-17 secretion, alteration of Treg phenotype and suppression of Th2 responses
Kluger, M. A., Nosko, A., Ramcke, T., Goerke, B., Meyer, M. C., Wegscheid, C., Luig, M., Tiegs, G., Stahl, R. A. K. & Steinmetz, O. M., 04.2017, In: CLIN EXP IMMUNOL. 188, 1, p. 63-78Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
THSD7A expression in human cancer
Stahl, P. R., Hoxha, E., Wiech, T., Schröder, C., Simon, R. & Stahl, R. A. K., 04.2017, In: GENE CHROMOSOME CANC. 56, 4, p. 314-327 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A pathogenic role of complement in arterial hypertension and hypertensive end organ damage
Wenzel, U. O., Bode, M., Köhl, J. & Ehmke, H., 01.03.2017, In: AM J PHYSIOL-HEART C. 312, 3, p. H349-H354Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Exacerbation of hepatitis E virus infection during anti-TNFα treatment
Behrendt, P., Lüth, S., Dammermann, W., Drave, S., Brown, R. J. P., Todt, D., Schnoor, U., Steinmann, E., Wedemeyer, H., Pischke, S. & Iking-Konert, C., 03.2017, In: JOINT BONE SPINE. 84, 2, p. 217-219Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo
Brockmann, L., Gagliani, N., Steglich, B., Giannou, A. D., Kempski, J., Pelczar, P., Geffken, M., Mfarrej, B., Huber, F., Herkel, J., Wan, Y. Y., Esplugues, E., Battaglia, M., Krebs, C. F., Flavell, R. A. & Huber, S., 01.02.2017, In: J IMMUNOL. 198, 3, p. 1130-1141Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An Indirect Immunofluorescence Method Facilitates Detection of Thrombospondin Type 1 Domain-Containing 7A-Specific Antibodies in Membranous Nephropathy
Hoxha, E., Beck, L. H., Wiech, T., Tomas, N. M., Probst, C., Mindorf, S., Meyer-Schwesinger, C., Zahner, G., Stahl, P. R., Schöpper, R., Panzer, U., Harendza, S., Helmchen, U., Salant, D. J. & Stahl, R. A. K., 02.2017, In: J AM SOC NEPHROL. 28, 2, p. 520-531Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical and Laboratory Consequences of Platelet Transfusion in Shiga Toxin-Mediated Hemolytic Uremic Syndrome
Beneke, J., Sartison, A., Kielstein, J. T., Haller, H., Nitschke, M., Kunzendorf, U., Loos, S., Kemper, M. J., Stahl, R. A. K., Menne, J. & German 2011 STEC-HUS outbreak study group, 01.2017, In: TRANSFUS MED REV. 31, 1, p. 51-55 5 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Influence of Liver Disease on Perioperative Outcome After Bariatric Surgery in a Northern German Cohort
Wolter, S., Duprée, A., Coelius, C., El Gammal, A., Kluwe, J., Sauer, N. & Mann, O., 01.2017, In: OBES SURG. 27, 1, p. 90-95 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
mTOR Regulates Endocytosis and Nutrient Transport in Proximal Tubular Cells
Grahammer, F., Ramakrishnan, S. K., Rinschen, M. M., Larionov, A. A., Syed, M., Khatib, H., Roerden, M., Sass, J. O., Helmstaedter, M., Osenberg, D., Kühne, L., Kretz, O., Wanner, N., Jouret, F., Benzing, T., Artunc, F., Huber, T. B. & Theilig, F., 01.2017, In: J AM SOC NEPHROL. 28, 1, p. 230-241 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles
Ergen, C., Heymann, F., Al Rawashdeh, W., Gremse, F., Bartneck, M., Panzer, U., Pola, R., Pechar, M., Storm, G., Mohr, N., Barz, M., Zentel, R., Kiessling, F., Trautwein, C., Lammers, T. & Tacke, F., 01.2017, In: BIOMATERIALS. 114, p. 106-120 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
T-Bet Enhances Regulatory T Cell Fitness and Directs Control of Th1 Responses in Crescentic GN
Nosko, A., Kluger, M. A., Diefenhardt, P., Melderis, S., Wegscheid, C., Tiegs, G., Stahl, R. A. K., Panzer, U. & Steinmetz, O. M., 01.2017, In: J AM SOC NEPHROL. 28, 1, p. 185-196Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel in vivo method to quantify slit diaphragm protein abundance in murine proteinuric kidney disease
Haase, R., Potthoff, S. A., Meyer-Schwesinger, C., Frosch, C., Wiech, T., Panzer, U., Königshausen, E., Stegbauer, J., Sellin, L., Rump, L. C., Quack, I. & Woznowski, M., 2017, In: PLOS ONE. 12, 6, p. e0179217Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Autoantikörper bei der membranösen Glomerulonephritis.
Hoxha, E., 2017, In: Nephro-news.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Der besondere Fall: Ein tierisch gefährlicher Kuss
Xiong, T., Schnoor, U., Jochum, J. & Janneck, M., 2017, In: Hamb Ärztebl. 2017, 5, p. 30-31Research output: SCORING: Contribution to journal › Newspaper articles › Transfer
Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4)
Lu, S., Liu, S., Wietelmann, A., Kojonazarov, B., Atzberger, A., Tang, C., Schermuly, R. T., Gröne, H-J. & Offermanns, S., 2017, In: PLOS ONE. 12, 8, p. e0183166Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetics of membranous nephropathy
Gupta, S., Köttgen, A., Hoxha, E., Brenchley, P., Bockenhauer, D., Stanescu, H. C. & Kleta, R., 2017, In: NEPHROL DIAL TRANSPL. 33, 9, p. 1493–1502Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Implementation of a Clinical Reasoning Course in the Internal Medicine trimester of the final year of undergraduate medical training and its effect on students' case presentation and differential diagnostic skills
Harendza, S., Krenz, I., Klinge, A., Wendt, U. & Janneck, M., 2017, In: GMS J MED EDU. 34, 5, p. Doc66Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influence of motivation, self-efficacy and situational factors on the teaching quality of clinical educators
Dybowski, C., Sehner, S. & Harendza, S., 2017, In: BMC MED EDUC.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Innate Immune Response in Kidney Ischemia/Reperfusion Injury: Potential Target for Therapy
Kezić, A., Stajic, N. & Thaiss, F., 2017, In: J IMMUNOL RES. 2017, p. 6305439Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Is the Age-Related Decline in Renal Function an Age-Associated Disease or Part of a Normal Aging Process?
Braun, F. & Brinkkoetter, P. T., 2017, In: GERONTOLOGY. 63, 4, p. 325-326 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Members of Bitter Taste Receptor Cluster Tas2r143/Tas2r135/Tas2r126 Are Expressed in the Epithelium of Murine Airways and Other Non-gustatory Tissues
Liu, S., Lu, S., Xu, R., Atzberger, A., Günther, S., Wettschureck, N. & Offermanns, S., 2017, In: FRONT PHYSIOL. 8, p. 849Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Membranöse Glomerulonephritis.
Hoxha, E., 2017, In: NEPHROLOGE.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Postgraduate Medical Education - an increasingly important focus of study and innovation
Kadmon, M., Ten Cate, O., Harendza, S. & Berberat, P., 2017, In: GMS J MED EDU. 34, 5, p. Doc70Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Using the Drosophila Nephrocyte to Model Podocyte Function and Disease
Helmstädter, M., Huber, T. B. & Hermle, T., 2017, In: FRONT PEDIATR. 5, p. 262Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2016
Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors
Kaminski, M. M., Tosic, J., Kresbach, C., Engel, H., Klockenbusch, J., Müller, A-L., Pichler, R., Grahammer, F., Kretz, O., Huber, T. B., Walz, G., Arnold, S. J. & Lienkamp, S. S., 12.2016, In: NAT CELL BIOL. 18, 12, p. 1269-1280 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17F Promotes Tissue Injury in Autoimmune Kidney Diseases
Riedel, J-H., Paust, H-J., Krohn, S., Turner, J-E., Kluger, M. A., Steinmetz, O. M., Krebs, C. F., Stahl, R. A. K. & Panzer, U., 12.2016, In: J AM SOC NEPHROL. 27, 12, p. 3666-3677Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Incidence of BK polyomavirus infection after kidney transplantation is independent of type of immunosuppressive therapy
Radtke, J., Dietze, N., Fischer, L., Achilles, E-G., Li, J., Scheidat, S., Thaiss, F., Nashan, B. & Koch, M., 12.2016, In: TRANSPL INFECT DIS. 18, 6, p. 850-855 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation
Danquah, W., Meyer-Schwesinger, C., Rissiek, B., Pinto, C., Serracant-Prat, A., Amadi, M., Iacenda, D., Knop, J-H., Hammel, A., Bergmann, P., Schwarz, N., Assunção, J., Rotthier, W., Haag, F., Tolosa, E., Bannas, P., Boué-Grabot, E., Magnus, T., Laeremans, T., Stortelers, C. & Nolte, F., 23.11.2016, In: SCI TRANSL MED. 8, 366, p. 366ra162Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MAGI-1 Interacts with Nephrin to Maintain Slit Diaphragm Structure through Enhanced Rap1 Activation in Podocytes
Ni, J., Bao, S., Johnson, R. I., Zhu, B., Li, J., Vadaparampil, J., Smith, C. M., Campbell, K. N., Grahammer, F., Huber, T. B., He, J. C., D'Agati, V. D., Chan, A. & Kaufman, L., 18.11.2016, In: J BIOL CHEM. 291, 47, p. 24406-24417 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney
Krebs, C. F., Paust, H-J., Krohn, S., Koyro, T., Brix, S. R., Riedel, J-H., Bartsch, P., Wiech, T., Meyer-Schwesinger, C., Huang, J., Fischer, N., Busch, C. P., Mittrücker, H-W., Steinhoff, U., Stockinger, B., Perez, L. G., Wenzel, U. O., Janneck, M., Steinmetz, O. M., Gagliani, N., Stahl, R. A. K., Huber, S., Turner, J-E. & Panzer, U., 15.11.2016, In: IMMUNITY. 45, 5, p. 1078-1092 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review