PD Dr. med. ID: 43961
Tim Ullrich Magnus
Publications
- 2024
Generation and characterization of antagonistic anti-human CD39 nanobodies
Menzel, S., Duan, Y., Hambach, J., Albrecht, B., Wendt-Cousin, D., Winzer, R., Tolosa, E., Rissiek, A., Guse, A. H., Haag, F., Magnus, T., Koch-Nolte, F. & Rissiek, B., 2024, In: FRONT IMMUNOL. 15, p. 1328306Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Homoarginine Associates with Carotid Intima-Media Thickness and Atrial Fibrillation and Predicts Adverse Events after Stroke
Schwieren, L., Jensen, M., Schulz, R., Lezius, S., Laxy, E., Milatz, M., Thomalla, G., Böger, R., Gerloff, C., Magnus, T., Schwedhelm, E. & Choe, C-U., 20.07.2023, In: LIFE-BASEL. 13, 7, 1590.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blood neurofilament light chain in Parkinson's disease
Buhmann, C., Magnus, T. & Choe, C-U., 06.2023, In: J NEURAL TRANSM. 130, 6, p. 755-762 8 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
The role of the ATP-adenosine axis in ischemic stroke
Schädlich, I. S., Winzer, R., Stabernack, J., Tolosa, E., Magnus, T. & Rissiek, B., 05.2023, In: SEMIN IMMUNOPATHOL. 45, 3, p. 347-365 19 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Unveiling the immunopathology of stroke: a comprehensive view on brain-immune interaction
Magnus, T. & Liesz, A., 05.2023, In: SEMIN IMMUNOPATHOL. 45, 3, p. 279-280 2 p.Research output: SCORING: Contribution to journal › Editorial › Research
Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system-No evidence for the role of neuronal P2X7 receptors in colitis
Jooss, T., Zhang, J., Zimmer, B., Rezzonico-Jost, T., Rissiek, B., Felipe Pelczar, P., Seehusen, F., Koch-Nolte, F., Magnus, T., Zierler, S., Huber, S., Schemann, M., Grassi, F. & Nicke, A., 04.2023, In: MUCOSAL IMMUNOL. 16, 2, p. 180-193 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A preclinical randomized controlled multi-centre trial of anti-interleukin-17A treatment for acute ischaemic stroke
Gelderblom, M., Koch, S., Strecker, J-K., Jørgensen, C., Garcia-Bonilla, L., Ludewig, P., Schädlich, I. S., Piepke, M., Degenhardt, K., Bernreuther, C., Pinnschmidt, H., Arumugam, T. V., Thomalla, G., Faber, C., Sedlacik, J., Gerloff, C., Minnerup, J., Clausen, B. H., Anrather, J. & Magnus, T., 23.03.2023, In: BRAIN COMMUN. 5, 2, p. fcad090Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Microglia and meningeal macrophages depletion delays the onset of experimental autoimmune encephalomyelitis
Montilla, A., Zabala, A., Er-Lukowiak, M., Rissiek, B., Magnus, T., Rodriguez-Iglesias, N., Sierra, A., Matute, C. & Domercq, M., 12.01.2023, In: CELL DEATH DIS. 14, 1, p. 16Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Interleukin-1 Mediates Ischemic Brain Injury via Induction of IL-17A in γδ T Cells and CXCL1 in Astrocytes
Schädlich, I. S., Vienhues, J. H., Jander, A., Piepke, M., Magnus, T., Lambertsen, K. L., Clausen, B. H. & Gelderblom, M., 12.2022, In: NEUROMOL MED. 24, 4, p. 437-451 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
P2X7 is expressed on human innate-like T lymphocytes and mediates susceptibility to ATP-induced cell death
Winzer, R., Serracant-Prat, A., Brock, V. J., Pinto-Espinoza, C., Rissiek, B., Amadi, M., Eich, N., Rissiek, A., Schneider, E., Magnus, T., Guse, A. H., Diercks, B-P., Koch-Nolte, F. & Tolosa, E., 11.2022, In: EUR J IMMUNOL. 52, 11, p. 1805-1818 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions
Wilmes, M., Pinto Espinoza, C., Ludewig, P., Stabernack, J., Liesz, A., Nicke, A., Gelderblom, M., Gerloff, C., Falzoni, S., Tolosa, E., Di Virgilio, F., Rissiek, B., Plesnilla, N., Koch-Nolte, F. & Magnus, T., 12.10.2022, In: J NEUROINFLAMM. 19, 1, 256.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Normalization of Aperiodic Electrocorticography Components Indicates Fine Motor Recovery After Sensory Cortical Stroke in Mice
Biskamp, J., Isla Cainzos, S., Higgen, F. L., Gerloff, C. & Magnus, T., 09.2022, In: STROKE. 53, 9, p. 2945–2953 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nt5e deficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model
Schädlich, I. S., Schnapauff, O., Pöls, L., Schrader, J., Tolosa, E., Rissiek, B. & Magnus, T., 17.06.2022, In: ISCIENCE. 25, 6, 104470.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes
Bub, A., Brenna, S., Alawi, M., Kügler, P., Gui, Y., Kretz, O., Altmeppen, H., Magnus, T. & Puig, B., 31.05.2022, In: CELL MOL LIFE SCI. 79, 6, p. 329 329.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Recurrent amnesia caused by early seizures after hippocampal infarction: A case report
Schlemm, E., Magnus, T., Rimmele, L. D., Münsterberg, J., Bester, M., Kessner, S. S., Gelderblom, M. & Gerloff, C., 10.01.2022, In: BMC NEUROL. 22, 1, 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Magnetic particle imaging for assessment of cerebral perfusion and ischemia
Ludewig, P., Graeser, M., Forkert, N. D., Thieben, F., Rández-Garbayo, J., Rieckhoff, J., Lessmann, K., Förger, F., Szwargulski, P., Magnus, T. & Knopp, T., 01.2022, In: WIRES NANOMED NANOBI. 14, 1, e1757.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Effective targeting of microglial P2X7 following intracerebroventricular delivery of nanobodies and nanobody-encoding AAVs
Pinto-Espinoza, C., Guillou, C., Rissiek, B., Wilmes, M., Javidi, E., Schwarz, N., Junge, M., Haag, F., Liaukouskaya, N., Wanner, N., Nicke, A., Stortelers, C., Tan, Y-V., Adriouch, S., Magnus, T. & Koch-Nolte, F., 2022, In: FRONT PHARMACOL. 13, 1029236.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models in vivo
Demeules, M., Scarpitta, A., Hardet, R., Gondé, H., Abad, C., Blandin, M., Menzel, S., Duan, Y., Rissiek, B., Magnus, T., Mann, A. M., Koch-Nolte, F. & Adriouch, S., 2022, In: FRONT IMMUNOL. 13, 1012534.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Real-Time Flow Cytometry as a Tool to Monitor Cellular Consequences of P2X7 Activation in Multiple Cell Populations Mixed in a Single FACS Tube
Veltkamp, A. W., Magnus, T. & Rissiek, B., 2022, The P2X7 Receptor: Methods and Protocols. Nicke, A. (ed.). 1 ed. New York, NY: HUMANA PRESS INC, p. 291-302 12 p. (Methods Mol Biol; vol. 2510).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2021
Serum Sphingosine-1-Phosphate Levels Are Associated With Severity and Outcome in Patients With Cerebral Ischemia
Schwedhelm, E., Schwieren, L., Tiedt, S., von Lucadou, M., Gloyer, N-O., Böger, R., Magnus, T., Daum, G., Thomalla, G., Gerloff, C. & Choe, C-U., 12.2021, In: STROKE. 52, 12, p. 3901-3907 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Combined Blockade of TIGIT and CD39 or A2AR Enhances NK-92 Cell-Mediated Cytotoxicity in AML
Brauneck, F., Seubert, E., Wellbrock, J., Schulze Zur Wiesch, J., Duan, Y., Magnus, T., Bokemeyer, C., Koch-Nolte, F., Menzel, S. & Fiedler, W., 29.11.2021, In: INT J MOL SCI. 22, 23, 12919.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response
Piepke, M., Clausen, B. H., Ludewig, P., Vienhues, J. H., Bedke, T., Javidi, E., Rissiek, B., Jank, L., Brockmann, L., Sandrock, I., Degenhardt, K., Jander, A., Roth, V., Schädlich, I. S., Prinz, I., Flavell, R. A., Kobayashi, Y., Renné, T., Gerloff, C., Huber, S., Magnus, T. & Gelderblom, M., 13.11.2021, In: J NEUROINFLAMM. 18, 1, 265.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression
Schneider, E., Winzer, R., Rissiek, A., Ricklefs, I., Meyer-Schwesinger, C., Ricklefs, F. L., Bauche, A., Behrends, J., Reimer, R., Brenna, S., Wasielewski, H., Lauten, M., Rissiek, B., Puig, B., Cortesi, F., Magnus, T., Fliegert, R., Müller, C. E., Gagliani, N. & Tolosa, E., 08.10.2021, In: NAT COMMUN. 12, 1, p. 5911Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Joint Vasculitis Registry in German-speaking countries (GeVas) - a prospective, multicenter registry for the follow-up of long-term outcomes in vasculitis
Iking-Konert, C., Wallmeier, P., Arnold, S., Adler, S., de Groot, K., Hellmich, B., Hoyer, B. F., Holl-Ulrich, K., Ihorst, G., Kaufmann, M., Kötter, I., Müller-Ladner, U., Magnus, T., Rech, J., Schubach, F., Schulze-Koops, H., Venhoff, N., Wiech, T., Villiger, P. & Lamprecht, P., 31.07.2021, In: BMC RHEUMATOL. 5, 1, 40.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of Extracranial Giant Cell Arteritis with Intracranial Involvement and its Rapidly Progressive Subtype
Beuker, C., Wankner, M. C., Thomas, C., Strecker, J-K., Schmidt-Pogoda, A., Schwindt, W., Schulte-Mecklenbeck, A., Gross, C., Wiendl, H., Barth, P. J., Eckert, B., Meinel, T. R., Arnold, M., Schaumberg, J., Krüger, S., Deb-Chatterji, M., Magnus, T., Röther, J. & Minnerup, J., 07.2021, In: ANN NEUROL. 90, 1, p. 118-129 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Profiling Complement System Components in Primary CNS Vasculitis
Deb-Chatterji, M., Keller, C. W., Koch, S., Wiendl, H., Gerloff, C., Magnus, T. & Lünemann, J. D., 08.05.2021, In: CELLS-BASEL. 10, 5, 1139.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Platelet endothelial cell adhesion molecule-1 is a gatekeeper of neutrophil transendothelial migration in ischemic stroke
Winneberger, J., Schöls, S., Lessmann, K., Rández-Garbayo, J., Bauer, A. T., Mohamud Yusuf, A., Hermann, D. M., Gunzer, M., Schneider, S. W., Fiehler, J., Gerloff, C., Gelderblom, M., Ludewig, P. & Magnus, T., 03.2021, In: BRAIN BEHAV IMMUN. 93, p. 277-287 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comment on “Mice Lacking the Purinergic Receptor P2X5 Exhibit Defective Inflammasome Activation and Early Susceptibility to Listeria monocytogenes”
Rissiek, B., Heeren, J., Koch-Nolte, F., Mittrücker, H-W. & Magnus, T., 15.02.2021, In: J IMMUNOL. 206, 4, 667.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Brain-Derived Extracellular Vesicles in Health and Disease: A Methodological Perspective
Brenna, S., Krisp, C., Altmeppen, H. C., Magnus, T. & Puig, B., 29.01.2021, In: INT J MOL SCI. 22, 3, p. 1365Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Identification of the Mouse T Cell ADP-Ribosylome Uncovers ARTC2.2 Mediated Regulation of CD73 by ADP-Ribosylation
Leutert, M., Duan, Y., Winzer, R., Menzel, S., Tolosa, E., Magnus, T., Hottiger, M. O., Koch-Nolte, F. & Rissiek, B., 2021, In: FRONT IMMUNOL. 12, p. 703719Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging
Graeser, M., Ludewig, P., Szwargulski, P., Foerger, F., Liebing, T., Forkert, N. D., Thieben, F., Magnus, T. & Knopp, T., 23.12.2020, In: PHYS MED BIOL. 65, 23, p. 235007Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice
Er-Lukowiak, M., Duan, Y., Rassendren, F., Ulmann, L., Nicke, A., Ufer, F., Friese, M. A., Koch-Nolte, F., Magnus, T. & Rissiek, B., 18.12.2020, In: ISCIENCE. 23, 12, p. 101870Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model
Ramírez-Fernández, A., Urbina-Treviño, L., Conte, G., Alves, M., Rissiek, B., Durner, A., Scalbert, N., Zhang, J., Magnus, T., Koch-Nolte, F., Plesnila, N., Deussing, J. M., Engel, T., Kopp, R. & Nicke, A., 16.11.2020, In: SCI REP-UK. 10, 1, p. 19876Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monitoring Intracranial Cerebral Hemorrhage Using Multicontrast Real-Time Magnetic Particle Imaging
Szwargulski, P., Wilmes, M., Javidi, E., Thieben, F., Graeser, M., Koch, M., Gruettner, C., Adam, G., Gerloff, C., Magnus, T., Knopp, T. & Ludewig, P., 27.10.2020, In: ACS NANO. 14, 10, p. 13913-13923 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs
Gallizioli, M., Miró-Mur, F., Otxoa-de-Amezaga, A., Cugota, R., Salas-Perdomo, A., Justicia, C., Brait, V. H., Ruiz-Jaén, F., Arbaizar-Rovirosa, M., Pedragosa, J., Bonfill-Teixidor, E., Gelderblom, M., Magnus, T., Cano, E., Del Fresno, C., Sancho, D. & Planas, A. M., 20.10.2020, In: CELL REP. 33, 3, p. 108291Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake
Brenna, S., Altmeppen, H. C., Mohammadi, B., Rissiek, B., Schlink, F., Ludewig, P., Krisp, C., Schlüter, H., Failla, A. V., Schneider, C., Glatzel, M., Puig, B. & Magnus, T., 27.08.2020, In: J EXTRACELL VESICLES. 9, 1, p. 1809065Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Show Me Your Friends and I Tell You Who You Are: The Many Facets of Prion Protein in Stroke
Puig, B., Yang, D., Brenna, S., Altmeppen, H. C. & Magnus, T., 02.07.2020, In: CELLS-BASEL. 9, 7Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Homoarginine- and Creatine-Dependent Gene Regulation in Murine Brains with l-Arginine:Glycine Amidinotransferase Deficiency
Jensen, M., Müller, C., Schwedhelm, E., Arunachalam, P., Gelderblom, M., Magnus, T., Gerloff, C., Zeller, T. & Choe, C-U., 09.03.2020, In: INT J MOL SCI. 21, 5, 1865.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intravenous Immunoglobulin (IVIg) Induce a Protective Phenotype in Microglia Preventing Neuronal Cell Death in Ischaemic Stroke
Häußler, V., Daehn, T., Rissiek, B., Roth, V., Gerloff, C., Arumugam, T. V., Magnus, T. & Gelderblom, M., 03.2020, In: NEUROMOL MED. 22, 1, p. 121-132 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Astrocytes and Microglia Are Resistant to NAD+-Mediated Cell Death Along the ARTC2/P2X7 Axis
Rissiek, B., Stabernack, J., Cordes, M., Duan, Y., Behr, S., Menzel, S., Magnus, T. & Koch-Nolte, F., 01.2020, In: FRONT MOL NEUROSCI. 12, p. 330Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deficits in developmental neurogenesis and dendritic spine maturation in mice lacking the serine protease inhibitor neuroserpin
Hermann, M., Reumann, R., Schostak, K., Kement, D., Gelderblom, M., Bernreuther, C., Frischknecht, R., Schipanski, A., Marik, S., Krasemann, S., Sepulveda-Falla, D., Schweizer, M., Magnus, T., Glatzel, M. & Galliciotti, G., 01.2020, In: MOL CELL NEUROSCI. 102, p. 103420Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating Endothelial Cells as Promising Biomarkers in the Differential Diagnosis of Primary Angiitis of the Central Nervous System
Deb-Chatterji, M., Pinnschmidt, H. O., Duan, Y., Haeussler, V., Rissiek, B., Gerloff, C., Thomalla, G. & Magnus, T., 2020, In: FRONT NEUROL. 11, p. 205Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Safety and efficacy of intravenous thrombolysis in stroke patients on prior antiplatelet therapy in the WAKE-UP trial
Frey, B. M., Boutitie, F., Cheng, B., Cho, T-H., Ebinger, M., Endres, M., Fiebach, J. B., Fiehler, J., Ford, I., Galinovic, I., Königsberg, A., Puig, J., Roy, P., Wouters, A., Magnus, T., Thijs, V., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Gerloff, C., Thomalla, G. & WAKE-UP Investigators, 2020, In: Neurol Res Pract. 2, p. 40Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Fatal PCR-negative herpes simplex virus-1 encephalitis with GABAA receptor antibodies
Schuster, S., Abrante, L., Matschke, J., Lütgehetmann, M., Holst, B., Gelderblom, M., Braass, H., Leypoldt, F. & Magnus, T., 11.2019, In: NEUROL-NEUROIMMUNOL. 6, 6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Induction of immunological tolerance to myelinogenic glial-restricted progenitor allografts
Li, S., Chol Oh, B., Arnold, A., Jablonska, A., Furtmüller, G., Qin, H-M., Boltze, J., Magnus, T. U., Ludewig, P., Janowski, M., Brandacher, G. & Walczak, P., 16.09.2019, In: BRAIN.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary Angiitis of the Central Nervous System: New Potential Imaging Techniques and Biomarkers in Blood and Cerebrospinal Fluid
Deb-Chatterji, M., Schuster, S., Haeussler, V., Gerloff, C., Thomalla, G. & Magnus, T., 06.06.2019, In: FRONT NEUROL. 10, p. 568Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the WAKE-UP Trial
Barow, E., Boutitie, F., Cheng, B., Cho, T-H., Ebinger, M., Endres, M., Fiebach, J. B., Fiehler, J., Ford, I., Galinovic, I., Nickel, A., Puig, J., Roy, P., Wouters, A., Magnus, T., Thijs, V., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Gerloff, C., Thomalla, G. & WAKE-UP Investigators, 01.06.2019, In: JAMA NEUROL. 76, 6, p. 641-649 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relapse rates and long-term outcome in primary angiitis of the central nervous system
Schuster, S., Ozga, A-K., Stellmann, J-P., Deb-Chatterji, M., Häußler, V., Matschke, J., Gerloff, C., Thomalla, G. & Magnus, T., 06.2019, In: J NEUROL. 266, 6, p. 1481-1489 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Autoimmunity After Ischemic Stroke and Brain Injury
Javidi, E. & Magnus, T. U., 02.04.2019, In: FRONT IMMUNOL.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Dynamics of brain perfusion and cognitive performance in revascularization of carotid artery stenosis
Schröder, J., Heinze, M., Günther, M., Cheng, B., Nickel, A., Schröder, T., Fischer, F., Kessner, S. S., Magnus, T., Fiehler, J., Larena-Avellaneda, A., Gerloff, C. & Thomalla, G., 13.03.2019, In: NEUROIMAGE-CLIN. 22, p. 101779Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neuroradiologic Characteristics of Primary Angiitis of the Central Nervous System According to the Affected Vessel Size
Thaler, C., Kaufmann-Bühler, A-K., Gansukh, T., Gansukh, A., Schuster, S., Bachmann, H., Thomalla, G., Magnus, T., Matschke, J., Fiehler, J. & Siemonsen, S., 03.2019, In: CLIN NEURORADIOL. 29, 1, p. 37-44 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA(2)DS(2)-VASc score in three cross-sectional studies
Cordts, K., Grzybowski, R., Lezius, S., Lüneburg, N., Atzler, D., Neu, A., Hornig, S., Böger, R. H., Gerloff, C., Magnus, T., Thomalla, G., Schwedhelm, E., Grant, P. J. & Choe, C-U., 15.02.2019, In: J NEUROL SCI. 397, p. 156-161 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Current Approaches and Future Perspectives for Nanobodies in Stroke Diagnostic and Therapy
Jank, L., Pinto-Espinoza, C., Duan, Y., Koch-Nolte, F., Magnus, T. U. & Rissiek, B., 03.01.2019, In: ANTIBODIES.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice
Puig, B., Altmeppen, H. C., Linsenmeier, L., Chakroun, K., Wegwitz, F., Piontek, U. K., Tatzelt, J., Bate, C., Magnus, T. & Glatzel, M., 01.2019, In: PLOS PATHOG. 15, 1, p. e1007520Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Generation and Function of Non-cell-bound CD73 in Inflammation
Schneider, E., Rissiek, A., Winzer, R., Puig, B., Rissiek, B., Haag, F., Mittrücker, H-W., Magnus, T. & Tolosa, E., 2019, In: FRONT IMMUNOL. 10, p. 1729Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2018
IL-33 modulates inflammatory brain injury but exacerbates systemic immunosuppression following ischemic stroke
Zhang, S. R., Piepke, M., Chu, H. X., Broughton, B. R., Shim, R., Wong, C. H., Lee, S., Evans, M. A., Vinh, A., Sakkal, S., Arumugam, T. V., Magnus, T., Huber, S., Gelderblom, M., Drummond, G. R., Sobey, C. G. & Kim, H. A., 20.09.2018, In: JCI INSIGHT. 3, 18Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular Communication of a Dying Neuron in Stroke
Puig, B., Brenna, S. & Magnus, T., 19.09.2018, In: INT J MOL SCI. 19, 9Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Rheumatoid meningitis A rare cause of aseptic meningitis with frequently stroke-like episodes
Schuster, S., Braaß, H., Iking-Konert, C., Schnoor, U., Matschke, J., Gerloff, C., Thomalla, G. & Magnus, T. U., 20.08.2018, In: NEUROL-CLIN PRACT. 8, 5, p. 451-455Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody
Kaczmarek-Hajek, K., Zhang, J., Kopp, R., Grosche, A., Rissiek, B., Saul, A., Bruzzone, S., Engel, T., Jooss, T., Krautloher, A., Schuster, S., Magnus, T., Stadelmann, C., Sirko, S., Koch-Nolte, F., Eulenburg, V. & Nicke, A., 03.08.2018, In: ELIFE. 7, p. e36217Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis
Zabala, A., Vazquez-Villoldo, N., Rissiek, B., Gejo, J., Martin, A., Palomino, A., Perez-Samartín, A., Pulagam, K. R., Lukowiak, M., Capetillo-Zarate, E., Llop, J., Magnus, T., Koch-Nolte, F., Rassendren, F., Matute, C. & Domercq, M., 08.2018, In: EMBO MOL MED. 10, 8, p. UNSP e8743Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
In Vivo Blockade of Murine ARTC2.2 During Cell Preparation Preserves the Vitality and Function of Liver Tissue-Resident Memory T Cells
Rissiek, B., Lukowiak, M., Raczkowski, F., Magnus, T., Mittrücker, H-W. & Koch-Nolte, F., 09.07.2018, In: FRONT IMMUNOL. 9, p. 1580Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prevalence of adult Pompe disease in patients with proximal myopathic syndrome and undiagnosed muscle biopsy
Golsari, A., Nasimzadah, A., Thomalla, G., Keller, S., Gerloff, C. & Magnus, T., 03.2018, In: NEUROMUSCULAR DISORD. 28, 3, p. 257-261 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-23 (Interleukin-23)-Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke
Gelderblom, M., Gallizioli, M., Ludewig, P., Thom, V., Arunachalam, P., Rissiek, B., Bernreuther, C., Glatzel, M., Korn, T., Arumugam, T. V., Sedlacik, J., Gerloff, C., Tolosa, E., Planas, A. M. & Magnus, T., 01.2018, In: STROKE. 49, 1, p. 155-164 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Danger signals in stroke and their role on microglia activation after ischemia
Gülke, E., Gelderblom, M. & Magnus, T., 2018, In: THER ADV NEUROL DISO. 11, p. 1-14Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Monitoring the Sensitivity of T Cell Populations Towards NAD Released During Cell Preparation
Rissiek, B., Lukowiak, M., Haag, F., Magnus, T. & Koch-Nolte, F., 2018, ADP-RIBOSYLATION AND NAD+ UTILIZING ENZYMES: METHODS AND PROTOCOLS . Chang, P. (ed.). 1 ed. HUMANA PRESS INC, Vol. 1813. p. 317-326 10 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2017
Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia
Rissiek, B., Menzel, S., Leutert, M., Cordes, M., Behr, S., Jank, L., Ludewig, P., Gelderblom, M., Rissiek, A., Adriouch, S., Haag, F., Hottiger, M. O., Koch-Nolte, F. & Magnus, T., 28.11.2017, In: SCI REP-UK. 7, 1, p. 16477Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Magnetic Particle Imaging for Real-Time Perfusion Imaging in Acute Stroke
Ludewig, P., Gdaniec, N., Sedlacik, J., Forkert, N. D., Szwargulski, P., Graeser, M., Adam, G., Kaul, M. G., Krishnan, K. M., Ferguson, R. M., Khandhar, A. P., Walczak, P., Fiehler, J., Thomalla, G., Gerloff, C., Knopp, T. & Magnus, T., 24.10.2017, In: ACS NANO. 11, 10, p. 10480-10488 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Klinisches Spektrum und Diagnosefindung bei rheumatoider Meningitis– Beschreibung von 5 Fällen
Braaß, H., Schuster, S., Lipp, M., Javidi, E., Schnoor, U., Iking-Konert, C., Matschke, J., Pötter-Nerger, M., Gerloff, C., Thomalla, G. & Magnus, T. U., 22.09.2017, Posterführung: Vaskulitiden und Neuroinfektiologie.Research output: SCORING: Contribution to book/anthology › Conference contribution - Poster › Research
Subtypes of primary angiitis of the CNS identified by MRI patterns reflect the size of affected vessels
Schuster, S., Bachmann, H., Thom, V., Kaufmann-Buehler, A-K., Matschke, J., Siemonsen, S., Glatzel, M., Fiehler, J., Gerloff, C., Magnus, T. & Thomalla, G., 09.2017, In: J NEUROL NEUROSUR PS. 88, 9, p. 749-755 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research
Real-world experience of treatment decision-making in carotid stenosis in a neurovascular board
Rimmele, D. L., Larena-Avellaneda, A., Alegiani, A. C., Rosenkranz, M., Schmidt, N. O., Regelsberger, J., Hummel, F. C., Magnus, T., Debus, E. S., Fiehler, J., Gerloff, C. & Thomalla, G., 25.07.2017, In: NEUROLOGY. 89, 4, p. 399-407 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke
Arunachalam, P., Ludewig, P., Melich, P., Arumugam, T. V., Gerloff, C., Prinz, I., Magnus, T. & Gelderblom, M., 07.2017, In: STROKE. 48, 7, p. 1957-1965 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hypointense Vessels Detected by Susceptibility-Weighted Imaging Identifies Tissue at Risk of Infarction in Anterior Circulation Stroke
Cheng, B., Schröder, N., Forkert, N. D., Ludewig, P., Kemmling, A., Magnus, T., Fiehler, J., Gerloff, C. & Thomalla, G., 07.2017, In: J NEUROIMAGING. p. n/a-n/aResearch output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia
Adesso, S., Magnus, T., Cuzzocrea, S., Campolo, M., Rissiek, B., Paciello, O., Autore, G., Pinto, A. & Marzocco, S., 12.06.2017, In: FRONT PHARMACOL. 8, p. 370Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An atypical role for the myeloid receptor Mincle in central nervous system injury
Arumugam, T. V., Manzanero, S., Furtado, M., Biggins, P. J., Hsieh, Y-H., Gelderblom, M., MacDonald, K. P., Salimova, E., Li, Y-I., Korn, O., Dewar, D., Macrae, I. M., Ashman, R. B., Tang, S-C., Rosenthal, N. A., Ruitenberg, M. J., Magnus, T. & Wells, C. A., 06.2017, In: J CEREBR BLOOD F MET. 37, 6, p. 2098-2111Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Edema is not a reliable diagnostic sign to exclude small brain metastases
Schneider, T., Kuhne, J. F., Bittrich, P., Schroeder, J., Magnus, T., Mohme, M., Grosser, M., Schoen, G., Fiehler, J. & Siemonsen, S., 11.05.2017, In: PLOS ONE. 12, 5, p. e0177217Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Silent Brain Infarctions and Leukoaraiosis in Patients With Retinal Ischemia: A Prospective Single-Center Observational Study
Golsari, A., Bittersohl, D., Cheng, B., Griem, P., Beck, C., Hassenstein, A., Nedelmann, M., Magnus, T., Fiehler, J., Gerloff, C. & Thomalla, G., 05.2017, In: STROKE. 48, 5, p. 1392-1396 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Antikörper-assoziierte autoimmune Enzephalopathien
Friese, M., Kastrup, O. & Magnus, T. U., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7., erweiterte und überarbeitete Auflage. Diener, H-C., Dieterich, M. & Gerloff, C. (eds.). 7 ed. Stuttgart: Kohlhammer, p. 770-780 11 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Correction: Cerebral Hemodynamics in Patients with Hemolytic Uremic Syndrome Assessed by Susceptibility Weighted Imaging and Four-Dimensional Non-Contrast MR Angiography
Löbel, U., Forkert, N. D., Schmitt, C. P., Dohrmann, T., Schroeder, M., Magnus, T., Kluge, S., Weiler-Normann, C., Bi, X., Fiehler, J. & Sedlacik, J., 2017, In: PLOS ONE. 12, 2, p. e0172450Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Paraneoplastische neurologische Symptome
Leypoldt, F., Magnus, T. U. & Voltz, R., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7. erweiterte und überarbeitete Auflage: Diener, H-C., Dieterich, M. & Gerloff, C. (Hrsg.). 7 ed. Stuttgart: Kohlhammer, p. 979-989 11 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Radikuläre Syndrome
Magnus, T. U., Bischoff, C. & Diener, H., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7. erweiterte und überarbeitete Auflage: Diener, H.-C., Dieterich, M. & Gerloff, C. (Hrsg.). 7 ed. Stuttgart: Kohlhammer, p. 1338-1351 13 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Riesenzellarteriitis und Polymyalgia rheumatica
Magnus, T. U. & Kleinschnitz, C., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7. erweiterte und überarbeitete Auflage: Diener, H-C., Dieterich, M. & Gerloff, C. (Hrsg.) . 7 ed. Stuttgart : Kohlhammer, p. 463-469 8 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Therapeutic Potential of Intravenous Immunoglobulin in Acute Brain Injury
Thom, V., Arumugam, T. V., Magnus, T. & Gelderblom, M., 2017, In: FRONT IMMUNOL. 8, p. 875Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Vaskulitiden des ZNS
Dichgans, M., Gerloff, C. & Magnus, T. U., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7. erweiterte und überarbeitete Auflage: Diener, H.-C., Dieterich, M. & Gerloff, C. (Hrsg.). 7 ed. Stuttgart: Kohlhammer, p. 438-462 24 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2016
Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation
Danquah, W., Meyer-Schwesinger, C., Rissiek, B., Pinto, C., Serracant-Prat, A., Amadi, M., Iacenda, D., Knop, J-H., Hammel, A., Bergmann, P., Schwarz, N., Assunção, J., Rotthier, W., Haag, F., Tolosa, E., Bannas, P., Boué-Grabot, E., Magnus, T., Laeremans, T., Stortelers, C. & Nolte, F., 23.11.2016, In: SCI TRANSL MED. 8, 366, p. 366ra162Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17 production by CSF lymphocytes as a biomarker for cerebral vasculitis
Thom, V., Schmidt, S., Gelderblom, M., Hackbusch, R., Kolster, M., Schuster, S., Thomalla, G., Keminer, O., Pleß, O., Bernreuther, C., Glatzel, M., Wegscheider, K., Gerloff, C., Magnus, T. & Tolosa, E., 21.03.2016, In: NEUROL-NEUROIMMUNOL. 3, 2, p. e214Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dendritic cells in brain diseases
Ludewig, P., Gallizioli, M., Urra, X., Behr, S., Brait, V. H., Gelderblom, M., Magnus, T. & Planas, A. M., 03.2016, In: BBA-MOL BASIS DIS. 1862, 3, p. 352-67 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative T2* mapping reveals early temporo-spatial dynamics in an ischemic stroke model
Gersing, A. S., Faymonville, A. M., Schwaiger, B. J., Leypoldt, F., Siemonsen, S., Zimmer, C., Magnus, T. & Fiehler, J., 01.02.2016, In: J NEUROSCI METH. 259, p. 83-89 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Frontal lobe dementia syndrome as a first manifestation of primary angiitis of the central nervous system (PACNS).
Bönstrup, M., Ott, K., Glatzel, M. & Magnus, T. U., 04.01.2016, In: CLIN NEUROL NEUROSUR. 141, p. 92-94Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cerebral Hemodynamics in Patients with Hemolytic Uremic Syndrome Assessed by Susceptibility Weighted Imaging and Four-Dimensional Non-Contrast MR Angiography
Löbel, U., Forkert, N. D., Schmitt, P., Dohrmann, T. W., Schroeder, M., Magnus, T., Kluge, S., Weiler-Normann, C., Bi, X., Fiehler, J. & Sedlacik, J., 2016, In: PLOS ONE. 11, 11, p. e0164863Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Primäre Vaskulitis des Zentralnervensystems
Schuster, S. & Magnus, T., 12.2015, In: Z RHEUMATOL. 74, 10, p. 854-62 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sichere Diagnose primärer ZNS-Vaskulitis nur mit bioptischem Nachweis
Schuster, S. & Magnus, T. U., 12.2015, In: Info Neurol Psych. 17, 12, p. 28-36Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Education
Danger signals in stroke
Gelderblom, M., Sobey, C. G., Kleinschnitz, C. & Magnus, T., 11.2015, In: AGEING RES REV. 24, Pt A, Special Issue, p. 77-82 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blockade of P2X7 receptors or pannexin-1 channels similarly attenuates postischemic damage
Cisneros-Mejorado, A., Gottlieb, M., Cavaliere, F., Magnus, T., Nolte, F., Scemes, E., Pérez-Samartín, A. & Matute, C., 05.2015, In: J CEREBR BLOOD F MET. 35, 5, p. 843-50 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Soluble plasma VE-cadherin concentrations are elevated in patients with STEC infection and haemolytic uraemic Syndrome: a case-control study
Doulgere, J., Otto, B., Nassour, M., Wolters-Eisfeld, G., Rohde, H., Magnus, T., Wagener, C. & Streichert, T., 01.01.2015, In: BMJ OPEN. 5, 3, p. e005659Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke
Gelderblom, M., Melzer, N., Schattling, B., Göb, E., Hicking, G., Arunachalam, P., Bittner, S., Ufer, F., Herrmann, A. M., Bernreuther, C., Glatzel, M., Gerloff, C., Kleinschnitz, C., Meuth, S. G., Friese, M. A. & Magnus, T., 01.11.2014, In: STROKE. 45, 11, p. 3395-3402 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of CCR2 in inflammatory conditions of the central nervous system
Chu, H. X., Arumugam, T. V., Gelderblom, M., Magnus, T., Drummond, G. R. & Sobey, C. G., 01.09.2014, In: J CEREBR BLOOD F MET. 34, 9, p. 1425-9 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Upregulation of Shiga toxin Receptor CD77/Gb3 and Interleukin-1β Expression in Brain of EHEC Patients with Hemolytic Uremic Syndrome and Neurologic Symptoms
Hagel, C., Krasemann, S., Löffler, J., Püschel, K., Magnus, T. & Glatzel, M., 02.07.2014, In: BRAIN PATHOL. 25, 2, p. 146-156Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cerebral Magnetic Resonance Imaging Findings in Adults with Haemolytic Uraemic Syndrome Following an Infection with Escherichia coli, Subtype O104:H4
Löbel, U., Eckert, B., Simova, O., Meier-Cillien, M., Kluge, S., Gerloff, C., Röther, J., Magnus, T. & Fiehler, J., 01.06.2014, In: CLIN NEURORADIOL. 24, 2, p. 111-9 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Improved Detection of Bacterial Central Nervous System Infections by Use of a Broad-Range PCR Assay
Meyer, T., Franke, G., Polywka, S. K. A., Lütgehetmann, M., Gbadamosi, J., Magnus, T. & Aepfelbacher, M., 01.05.2014, In: J CLIN MICROBIOL. 52, 5, p. 1751-3 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke
Cheng, Y-L., Park, J-S., Manzanero, S., Choi, Y., Baik, S-H., Okun, E., Gelderblom, M., Fann, D. Y-W., Magnus, T., Launikonis, B. S., Mattson, M. P., Sobey, C. G., Jo, D-G. & Arumugam, T. V., 01.02.2014, In: NEUROBIOL DIS. 62, p. 286-95 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immune activation in amyloid-β-related angiitis correlates with decreased parenchymal amyloid-β plaque load
Bogner, S., Bernreuther, C., Matschke, J., Barrera-Ocampo, A. A., Sepulveda-Falla, D., Leypoldt, F., Magnus, T., Haag, F., Bergmann, M., Brück, W., Vogelgesang, S. & Glatzel, M., 01.01.2014, In: NEURODEGENER DIS. 13, 1, p. 38-44 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neuropsychological outcome after complicated Shiga toxin-producing Escherichia coli infection
Simova, O., Weineck, G., Schütze, T., Wegscheider, K., Panzer, U., Stahl, R. A. K., Gerloff, C. & Magnus, T., 01.01.2014, In: PLOS ONE. 9, 7, p. e103029Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
γδ T cells as early sensors of tissue damage and mediators of secondary neurodegeneration
Gelderblom, M., Arunachalam, P. & Magnus, T., 01.01.2014, In: FRONT CELL NEUROSCI. 8, p. 368Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blocking of α4 Integrin Does Not Protect From Acute Ischemic Stroke in Mice
Langhauser, F., Kraft, P., Göb, E., Leinweber, J., Schuhmann, M. K., Lorenz, K., Gelderblom, M., Bittner, S., Meuth, S. G., Wiendl, H., Magnus, T. & Kleinschnitz, C., 2014, In: STROKE. 45, 6, p. 1799-+Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nanobodies as modulators of inflammation: potential applications for acute brain injury
Rissiek, B., Nolte, F. & Magnus, T., 2014, In: FRONT CELL NEUROSCI. 8, p. 344Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PI3Kδ inhibition reduces TNF secretion and neuroinflammation in a mouse cerebral stroke model
Low, P. C., Manzanero, S., Mohannak, N., Narayana, V. K., Nguyen, T. H., Kvaskoff, D., Brennan, F. H., Ruitenberg, M. J., Gelderblom, M., Magnus, T., Kim, H. A., Broughton, B. R. S., Sobey, C. G., Vanhaesebroeck, B., Stow, J. L., Arumugam, T. V. & Meunier, F. A., 2014, In: NAT COMMUN. 5, p. 3450Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Plasma levels of neuron specific enolase quantify the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis
Gelderblom, M., Daehn, T., Schattling, B., Ludewig, P., Bernreuther, C., Arunachalam, P., Matschke, J., Glatzel, M., Gerloff, C., Friese, M. A. & Magnus, T., 01.11.2013, In: NEUROBIOL DIS. 59, p. 177-82 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: case report
Leypoldt, F., Titulaer, M. J., Aguilar, E., Walther, J., Bönstrup, M., Havemeister, S., Teegen, B., Lütgehetmann, M., Rosenkranz, M., Magnus, T. & Dalmau, J., 29.10.2013, In: NEUROLOGY. 81, 18, p. 1637-9 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke
Ludewig, P., Sedlacik, J., Gelderblom, M., Bernreuther, C., Korkusuz, Y., Wagener, C., Gerloff, C., Fiehler, J., Magnus, T. & Horst, A. K., 27.09.2013, In: CIRC RES. 113, 8, p. 1013-22 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies
Choe, C., Atzler, D., Wild, P. S., Carter, A. M., Böger, R. H., Ojeda Echevarria, F. M., Simova, O., Stockebrand, M., Lackner, K., Nabuurs, C., Marescau, B., Streichert, T., Müller, C., Lüneburg, N., De Deyn, P. P., Benndorf, R. A., Baldus, S., Gerloff, C., Blankenberg, S., Heerschap, A., Grant, P. J., Magnus, T., Zeller, T., Isbrandt, D. & Schwedhelm, E., 24.09.2013, In: CIRCULATION. 128, 13, p. 1451-61 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reply: Blood-cerebrospinal fluid barrier dysfunction in patients with neurological symptoms during the 2011 Northern German Escherichia coli serotype O104:H4 outbreak
Magnus, T., Simova, O., Meier-Cillien, M., Röther, J. & Gerloff, C., 01.08.2013, In: BRAIN. 136, Pt 8, p. e242Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Clinical features of critically ill patients with Shiga toxin-induced hemolytic uremic syndrome
Braune, S. A., Wichmann, D., Heinz, M. C., Nierhaus, A., Becker, H., Meyer, T. N., Meyer, G. P., Müller-Schulz, M., Fricke, J., de Weerth, A., Höpker, W-W., Fiehler, J., Magnus, T., Gerloff, C., Panzer, U., Stahl, R. A. K., Wegscheider, K. & Kluge, S., 01.07.2013, In: CRIT CARE MED. 41, 7, p. 1702-10 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Leukocyte-derived MMP9 is crucial for the recruitment of proinflammatory macrophages in experimental glomerulonephritis
Kluger, M. A., Zahner, G., Paust, H-J., Schaper, M., Magnus, T., Panzer, U. & Stahl, R. A. K., 01.05.2013, In: KIDNEY INT. 83, 5, p. 865-77 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation
Gelderblom, M., Neumann, M., Ludewig, P., Bernreuther, C., Krasemann, S., Arunachalam, P., Gerloff, C., Glatzel, M. & Magnus, T., 01.01.2013, In: PLOS ONE. 8, 5, p. e63118Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke
Fann, D. Y-W., Lee, S. Y., Manzanero, S., Tang, S. C., Gelderblom, M., Chunduri, P., Bernreuther, C., Glatzel, M., Cheng, Y. L., Thundyil, J., Widiapradja, A., Lok, K. Z., Foo, S. L., Wang, Y. C., Li, Y. I., Drummond, G. R., Basta, M., Magnus, T., Jo, D. G., Mattson, M. P., Sobey, C. G. & Arumugam, T. V., 01.01.2013, In: CELL DEATH DIS. 4, p. e790Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Report on the 5'th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 25th - Oct. 27th, 2013
Linker, R. A., Magnus, T., Korn, T., Kleinschnitz, C., Meuth, S. G. & speakers at the 5’th NEUROWIND e.V. scientific meeting, 01.01.2013, In: Exp Transl Stroke Med. 5, 1, p. 15Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Kleinschnitz, C., Kraft, P., Dreykluft, A., Hagedorn, I., Göbel, K., Schuhmann, M. K., Langhauser, F., Helluy, X., Schwarz, T., Bittner, S., Mayer, C. T., Brede, M., Varallyay, C., Pham, M., Bendszus, M., Jakob, P., Magnus, T., Meuth, S. G., Iwakura, Y., Zernecke, A., Sparwasser, T., Nieswandt, B., Stoll, G. & Wiendl, H., 2013, In: BLOOD. 121, 4, p. 679-691 13 p., 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Risk factors for development of hemolytic uremic syndrome in a cohort of adult patients with STEC 0104:H4 infection.
Zoufaly, A., Cramer, J. P., Vettorazzi, E., Sayk, F., Bremer, J. P., Koop, I., de Weerth, A., Schmiedel, S., Jordan, S., Zimmermann-Fraedrich, K., Asselborn, N. H., Nitschke, M., Neumann-Grutzeck, C., Magnus, T., Rüther, C., Fellermann, K., Stahl, R. K., Wegscheider, K. & Lohse, A. W., 2013, In: PLOS ONE. 8, 3, p. e59209 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2012
Neurologische Manifestationen von Vaskulitiden und primäre ZNS-Vaskulitis
Magnus, T., Melms, A., Kötter, I. & Holle, J. U., 01.09.2012, In: Z RHEUMATOL. 71, 7, p. 551-563 13 p., 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease.
Leypoldt, F., Buchert, R., Kleiter, I., Marienhagen, J., Gelderblom, M., Magnus, T., Dalmau, J., Gerloff, C. & Lewerenz, J., 01.07.2012, In: J NEUROL NEUROSUR PS. 83, 7, p. 681-686 6 p., 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
C5a receptor (CD88) inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic model.
Thundyil, J., Pavlovski, D., Hsieh, Y-H., Gelderblom, M., Magnus, T., Fairlie, D. P. & Arumugam, T. V., 2012, In: NEUROMOL MED. 14, 1, p. 30-39 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dimethylarginine dimethylaminohydrolase1 is an organ-specific mediator of end organ damage in a murine model of hypertension.
Sydow, K., Schmitz, C., von Leitner, E-C., von Leitner, R., Klinke, A., Atzler, D., Krebs, C., Wieboldt, H., Ehmke, H., Schwedhelm, E., Meinertz, T., Blankenberg, S., Böger, R. H., Magnus, T., Baldus, S. & Wenzel, U., 2012, In: PLOS ONE. 7, 10, p. 48150 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.
Turner, J. E., Krebs, C., Tittel, A. P., Paust, H-J., Meyer-Schwesinger, C., Bennstein, S. B., Steinmetz, O., Prinz, I., Magnus, T., Korn, T., Stahl, R. A. K., Kurts, C. & Panzer, U., 2012, In: J AM SOC NEPHROL. 23, 9, p. 1486-1495 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immune mechanisms of stroke.
Magnus, T., Wiendl, H. & Kleinschnitz, C., 2012, In: CURR OPIN NEUROL. 25, 3, p. 334-340 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways.
Widiapradja, A., Vegh, V., Lok, K. Z., Manzanero, S., Thundyil, J., Gelderblom, M., Cheng, Y-L., Pavlovski, D., Tang, S-C., Jo, D-G., Magnus, T., Chan, S. L., Sobey, C. G., Reutens, D., Basta, M., Mattson, M. P. & Arumugam, T. V., 2012, In: J NEUROCHEM. 122, 2, p. 321-332 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., Thom, V., Friese, M. A., Prinz, I., Hölscher, C., Glatzel, M., Korn, T., Gerloff, C., Tolosa, E. & Magnus, T., 2012, In: BLOOD. 120, 18, p. 3793-3802 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Report on the 3'rd scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 4'th - Nov. 6'th, 2011.
Kleinschnitz, C., Meuth, S. G., Magnus, T., Korn, T. & Linker, R. A., 2012, In: Exp Transl Stroke Med. 4, 1, p. 2 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Report on the 4'th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 2'nd - Nov. 4'th, 2012.
Linker, R. A., Meuth, S. G., Magnus, T., Korn, T. & Kleinschnitz, C., 2012, In: Exp Transl Stroke Med. 4, 1, p. 22 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.
Gelderblom, M., Leypoldt, F., Lewerenz, J., Birkenmayer, G., Orozco, D., Ludewig, P., Thundyil, J., Arumugam, T. V., Gerloff, C., Tolosa, E., Maher, P. & Magnus, T., 2012, In: J CEREBR BLOOD F MET. 32, 5, p. 835-843 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The neurological syndrome in adults during the 2011 northern German E. coli serotype O104:H4 outbreak.
Magnus, T., Röther, J., Simova, O., Meier-Cillien, M., Repenthin, J., Möller, F., Gbadamosi, J., Panzer, U., Wengenroth, M., Hagel, C., Kluge, S., Stahl, R. A. K., Wegscheider, K., Urban, P., Eckert, B., Glatzel, M., Fiehler, J. & Gerloff, C., 2012, In: BRAIN. 135, Pt 6, p. 1850-1859 Pt 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
[Autoimmune synaptic encephalopathies].
Friese, M. A. & Magnus, T., 2011, In: NERVENARZT. 82, 10, p. 1239-1249 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Calorie restriction and stroke.
Manzanero, S., Gelderblom, M., Magnus, T. & Arumugam, T. V., 2011, In: Exp Transl Stroke Med. 3, p. 8Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CD38 exacerbates focal cytokine production, postischemic inflammation and brain injury after focal cerebral ischemia.
Choe, C-U., Lardong, K., Gelderblom, M., Ludewig, P., Leypoldt, F., Koch Nolte, F., Gerloff, C. & Magnus, T., 2011, In: PLOS ONE. 6, 5, p. 19046 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke.
Arumugam, T. V., Cheng, Y-L., Choi, Y., Choi, Y-H., Yang, S., Yun, Y-K., Park, J-S., Yang, D. K., Thundyil, J., Gelderblom, M., Karamyan, V. T., Tang, S-C., Chan, S. L., Magnus, T., Sobey, C. G. & Jo, D-G., 2011, In: MOL PHARMACOL. 80, 1, p. 23-31 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nitroxyl in the central nervous system.
Choe, C-U., Lewerenz, J., Gerloff, C., Magnus, T. & Donzelli, S., 2011, In: ANTIOXID REDOX SIGN. 14, 9, p. 1699-1711 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Report on the 2nd scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 29'th - Oct. 31'st, 2010.
Magnus, T., Linker, R. A., Meuth, S. G., Kleinschnitz, C. & Korn, T., 2011, In: Exp Transl Stroke Med. 3, 1, p. 3 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Seventy years of episodic stiffness: an unusual case of neuromyotonia.
Ganos, C., Münchau, A., Bäumer, T., Gerloff, C. & Magnus, T., 2011, In: MOVEMENT DISORD. 26, 7, p. 1360-1361 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Report on the 1st scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Mittenwalde/Motzen, Germany, Oct. 30th - Nov. 1st, 2009.
Magnus, T., Linker, R., Meuth, S. G., Kleinschnitz, C. & Korn, T., 2010, In: Exp Transl Stroke Med. 2, p. 7Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity
Choe, C., Lewerenz, J., Fischer, G., Uliasz, T. F., Espey, M. G., Hummel, F. C., King, S. B., Schwedhelm, E., Böger, R. H., Gerloff, C., Hewett, S. J., Magnus, T. & Donzelli, S., 01.09.2009, In: J NEUROCHEM. 110, 6, p. 1766-73 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HNO exacerbates ischemic cerebral injury and oxidative neurotoxicity.
Choe, C-U., Lewerenz, J., Fischer, G., Uliasz, T. F., Espey, M. G., Hummel, F., Bruce King, S., Schwedhelm, E., Böger, R., Gerloff, C., Hewett, S. J., Magnus, T. & Donzelli, S., 2009, In: J NEUROCHEM.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Temporal and spatial dynamics of cerebral immune cell accumulation in stroke.
Gelderblom, M., Leypoldt, F., Steinbach, K., Behrens, D., Choe, C-U., Siler, D. A., Arumugam, T. V., Orthey, E., Gerloff, C., Tolosa, E. & Magnus, T., 2009, In: STROKE. 40, 5, p. 1849-1857 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Adult glial precursor proliferation in mutant SOD1G93A mice.
Magnus, T., Carmen, J., Deleon, J., Xue, H., Pardo, A. C., Lepore, A. C., Mattson, M. P., Rao, M. S. & Maragakis, N. J., 2008, In: GLIA. 56, 2, p. 200-208 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stem cell myths.
Magnus, T., Liu, Y., Parker, G. C. & Rao, M. S., 2008, In: PHILOS T R SOC B. 363, 1489, p. 9-22 1489.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting TNF-alpha receptors for neurotherapeutics.
Chadwick, W., Magnus, T., Martin, B., Keselman, A., Mattson, M. P. & Maudsley, S., 2008, In: TRENDS NEUROSCI. 31, 10, p. 504-511 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation.
Lathia, J. D., Okun, E., Tang, S-C., Griffioen, K., Cheng, A., Mughal, M. R., Laryea, G., Selvaraj, P. K., Ffrench-Constant, C., Magnus, T., Arumugam, T. V. & Mattson, M. P., 2008, In: J NEUROSCI. 28, 51, p. 13978-13984 51.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Autoimmune modulation of astrocyte-mediated homeostasis.
Korn, T., Rao, M. & Magnus, T., 2007, In: NEUROMOL MED. 9, 1, p. 1-16 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor response.
Cassiani-Ingoni, R., Muraro, P. A., Magnus, T., Reichert-Scrivner, S., Schmidt, J., Huh, J., Quandt, J. A., Bratincsak, A., Shahar, T., Eusebi, F., Sherman, L. S., Mattson, M. P., Martin, R. & Rao, M. S., 2007, In: J NEUROPATH EXP NEUR. 66, 7, p. 637-649 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes.
Magnus, T., Coksaygan, T., Korn, T., Xue, H., Arumugam, T. V., Mughal, M. R., Eckley, D. M., Tang, S-C., Detolla, L., Rao, M. S., Cassiani-Ingoni, R. & Mattson, M. P., 2007, In: J NEUROSCI RES. 85, 10, p. 2126-2137 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death.
Arumugam, T. V., Tang, S-C., Lathia, J. D., Cheng, A., Mughal, M. R., Chigurupati, S., Magnus, T., Chan, S. L., Jo, D-G., Ouyang, X., Fairlie, D. P., Granger, D. N., Vortmeyer, A., Basta, M. & Mattson, M. P., 2007, In: P NATL ACAD SCI USA. 104, 35, p. 14104-14109 35.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neuroprotective actions of a histidine analogue in models of ischemic stroke.
Tang, S-C., Arumugam, T. V., Cutler, R. G., Jo, D-G., Magnus, T., Chan, S. L., Mughal, M. R., Telljohann, R. S., Nassar, M., Ouyang, X., Calderan, A., Ruzza, P., Guiotto, A. & Mattson, M. P., 2007, In: J NEUROCHEM. 101, 3, p. 729-736 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.
Lathia, J. D., Patton, B., Eckley, D. M., Magnus, T., Mughal, M. R., Sasaki, T., Caldwell, M. A., Rao, M. S., Mattson, M. P. & Ffrench-Constant, C., 2007, In: J COMP NEUROL. 505, 6, p. 630-643 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits.
Tang, S-C., Arumugam, T. V., Xu, X., Cheng, A., Mughal, M. R., Jo, D. G., Lathia, J. D., Siler, D. A., Chigurupati, S., Ouyang, X., Magnus, T., Camandola, S. & Mattson, M. P., 2007, In: P NATL ACAD SCI USA. 104, 34, p. 13798-13803 34.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Revisiting the astrocyte-oligodendrocyte relationship in the adult CNS.
Carmen, J., Magnus, T., Cassiani-Ingoni, R., Sherman, L., Rao, M. S. & Mattson, M. P., 2007, In: PROG NEUROBIOL. 82, 3, p. 151-162 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2002
Astrocytes are less efficient in the removal of apoptotic lymphocytes than microglia cells: implications for the role of glial cells in the inflamed central nervous system
Magnus, T., Chan, A., Linker, R. A., Toyka, K. V. & Gold, R., 09.2002, In: J NEUROPATH EXP NEUR. 61, 9, p. 760-6 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review