Center for Oncology
Publications
- 2009
Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.
Michaelis, M., Rothweiler, F., Klassert, D., von Deimling, A., Riecken, K., Fehse, B., Kammerer, B., Doerr, H. W. & Cinatl, J., 2009, In: CANCER RES. 69, 2, p. 416-421 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Risk factors for therapy-related myelodysplastic syndrome and acute myeloid leukemia treated with allogeneic stem cell transplantation.
Kröger, N., Brand, R., van Biezen, A., Zander, A. R., Dierlamm, J., Niederwieser, D., Devergie, A., Ruutu, T., Cornish, J., Ljungman, P., Gratwohl, A., Cordonnier, C., Beelen, D., Deconinck, E., Symeonidis, A. & de Witte, T., 2009, In: HAEMATOLOGICA. 94, 4, p. 542-549 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RQ-PCR based WT1 expression in comparison to BCR-ABL quantification can predict Philadelphia negative clonal evolution in patients with imatinib-treated chronic myeloid leukaemia.
Schnittger, S., Bacher, U., Kern, W., Tschulik, C., Weiss, T., Haferlach, C. & Haferlach, T., 2009, In: BRIT J HAEMATOL. 146, 6, p. 665-668 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Safety of conditioning agents for allogeneic haematopoietic transplantation.
Bacher, U., Klyuchnikov, E., Wiedemann, B., Kröger, N. & Zander, A. R., 2009, In: EXPERT OPIN DRUG SAF. 8, 3, p. 305-315 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Salvage treatment in germ cell tumors : high-dose chemotherapy and the impact of prognostic factors]
Lorch, A., Oechsle, K., Bokemeyer, C. & Beyer, J., 2009, In: UROLOGE. 48, 4, p. 364-371 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Second allogeneic stem cell transplantation in myeloid malignancies.
Hartwig, M., Ocheni, S., Asenova, S., Wiedemann, B., Zabelina, T., Ayuketang Ayuk, F., Kabisch, H., Erttmann, R., Kröger, N., Zander, A. R. & Bacher, U., 2009, In: ACTA HAEMATOL-BASEL. 122, 4, p. 185-192 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Second and subsequent recurrences of osteosarcoma: presentation, treatment, and outcomes of 249 consecutive cooperative osteosarcoma study group patients.
Bielack, S. S., Kempf-Bielack, B., Branscheid, D., Carrle, D., Friedel, G., Helmke, K., Kevric, M., Jundt, G., Kühne, T., Maas, R., Schwarz, R., Zoubek, A. & Jürgens, H., 2009, In: J CLIN ONCOL. 27, 4, p. 557-565 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Second-generation tyrosine kinase inhibitors in the post-transplant period in patients with chronic myeloid leukemia or Philadelphia-positive acute lymphoblastic leukemia.
Klyuchnikov, E., Schafhausen, P., Kröger, N., Brümmendorf, T., Osanmaz, O., Asenova, S., Zabelina, T., Ocheni, S., Ayuketang Ayuk, F., Zander, A. R. & Bacher, U., 2009, In: ACTA HAEMATOL-BASEL. 122, 1, p. 6-10 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sensitising leukemic cells by targeting microenvironment.
Klyuchnikov, E. & Kröger, N., 2009, In: LEUKEMIA LYMPHOMA. 50, 3, p. 319-320 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Severe aplastic anaemia following leflunomide therapy.
Wüsthof, M., Smirnova, A., Bacher, U., Kröger, N., Zander, A. R., Schuch, G. & Bokemeyer, C., 2009, In: RHEUMATOLOGY.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sex-specific aspects of tumor therapy.
Borgmann, K., Dikomey, E., Petersen, C., Feyer, P. & Hoeller, U., 2009, In: RADIAT ENVIRON BIOPH. 48, 2, p. 115-124 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited.
Loges, S., Mazzone, M., Hohensinner, P. & Carmeliet, P., 2009, In: CANCER CELL. 15, 3, p. 167-170 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Similar patterns of chromosome abnormalities in CML occur in addition to the Philadelphia chromosome with or without tyrosine kinase inhibitor treatment.
Haferlach, C., Bacher, U., Schnittger, S., Weiss, T., Kern, W. & Haferlach, T., 2009, In: LEUKEMIA.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Single-center management of 136 patients with cancer of unknown primary site (CUP syndrome) over a period of 10 years.
Thoem, I., Rogers, C., Andritzky, B., Witzel, I., Schuch, G., Hossfeld, D. K., Bokemeyer, C. & Laack, E., 2009, In: ONKOLOGIE. 32, 12, p. 741-746 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Single Nucleotide Polymorphism in the Mutational Hotspot of WT1 Predicts a Favorable Outcome in Patients With Cytogenetically Normal Acute Myeloid Leukemia.
Damm, F., Heuser, M., Morgan, M., Yun, H., Großhennig, A., Göhring, G., Schlegelberger, B., Döhner, K., Ottmann, O., Lübbert, M., Heit, W., Kanz, L., Schlimok, G., Raghavachar, A., Fiedler, W., Kirchner, H., Döhner, H., Heil, G., Ganser, A. & Krauter, J., 2009, In: J CLIN ONCOL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sleep disturbances and emotional distress in the acute course of hematopoietic stem cell transplantation.
Rischer, J., Scherwath, A., Zander, A. R., Koch, U. & Schulz-Kindermann, F., 2009, In: BONE MARROW TRANSPL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Stage-specific treatment for testicular germ cell tumours]
Heidenreich, A., Bokemeyer, C. & Souchon, R., 2009, In: UROLOGE. 48, 4, p. 377-385 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Standard graft-versus-host disease prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: a randomised, open-label, multicentre phase 3 trial.
Finke, J., Bethge, W. A., Schmoor, C., Ottinger, H. D., Stelljes, M., Zander, A. R., Volin, L., Ruutu, T., Heim, D. A., Schwerdtfeger, R., Kolbe, K., Mayer, J., Maertens, J. A., Linkesch, W., Holler, E., Koza, V., Bornhäuser, M., Einsele, H., Kolb, H-J., Bertz, H., Egger, M., Grishina, O. & Socié, G., 2009, In: LANCET ONCOL. 10, 9, p. 855-864 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stehen kognitive Funktionen im Zusammenhang mit Angst, Depression und Posttraumatischer Belastungsstörung bei Brustkrebspatientinnen nach onkologischer Behandlung?
Schirmer, L., Mehnert, A., Scherwath, A., Schleimer, B., Schulz-Kindermann, F., Zander, A. R. & Koch-Gromus, U., 2009, In: Z PSYCHIATR PSYCH PS. 57, 1, p. 33-42 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stem cell marking with promotor-deprived self-inactivating retroviral vectors does not lead to induced clonal imbalance.
Cornils, K., Lange, C., Schambach, A., Brugman, M. H., Nowak, R., Lioznov, M., Baum, C. & Fehse, B., 2009, In: MOL THER. 17, 1, p. 131-143 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Successful expansion but not complete restriction of tropism of adeno-associated virus by in vivo biopanning of random virus display peptide libraries
Michelfelder, S., Kohlschütter, J., Skorupa, A., Pfennings, S., Müller, O., Kleinschmidt, J. A. & Trepel, M., 2009, In: PLOS ONE. 4, 4, p. e5122Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Successful unrelated donor stem cell transplantation for advanced myelofibrosis in an adult patient with history of orthotopic liver transplantation.
Perz, J. B., Hegenbart, U., Kröger, N., Otto, G., Ho, A. D. & Dreger, P., 2009, In: HAEMATOLOGICA. 94, 4, p. 594-596 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Syngenic graft-versus-chronic-myeloid-leukemia-effect?
Ocheni, S., Schafhausen, P., Bacher, U., Fehse, B. & Kröger, N., 2009, In: CTT-Cell Ther Transpl. 1, 3, p. 66-68 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis.
Schultze, A., Decker, S., Wellbrock, J., Horst, A., Vohwinkel, G., Schuch, G., Bokemeyer, C., Loges, S. & Fiedler, W., 2009, In: INVEST NEW DRUG.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapy.
Keller, G., Brassat, U., Balabanov, M., Heim, D., Wege, H. & Brümmendorf, T., 2009, In: HEMATOL ONCOL. 27, 3, p. 123-129 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The changing scene of allogeneic stem cell transplantation for chronic myeloid leukemia-a report from the German Registry covering the period from 1998 to 2004.
Bacher, U., Klyuchnikov, E., Zabelina, T., Ottinger, H., Beelen, D., Schrezenmeier, H., Ehninger, G., Müller, C., Berger, J., Suttorp, M., Kolb, H-J., Kröger, N. & Zander, A. R., 2009, In: ANN HEMATOL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The extreme radiosensitivity of the squamous cell carcinoma SKX is due to a defect in double-strand break repair.
Kasten-Pisula, U., Menegakis, A., Brammer, I., Borgmann, K., Mansour, W., Degenhardt, S., Krause, M., Schreiber, A., Dahm-Daphi, J., Petersen, C., Dikomey, E. & Baumann, M., 2009, In: RADIOTHER ONCOL. 90, 2, p. 257-264 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The impact of cytomorphology, cytogenetics, molecular genetics, and immunophenotyping in a comprehensive diagnostic workup of myelodysplastic syndromes.
Bacher, U., Haferlach, T., Kern, W., Weiss, T., Schnittger, S. & Haferlach, C., 2009, In: CANCER-AM CANCER SOC. 115, 19, p. 4524-4532 19.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Therapie des metastasierten Kolonkarzinoms
Folprecht, G., Bokemeyer, C. & Weitz, J., 2009, In: ONKOLOGE. 15, p. 1223-1234Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The t(14;18)(q32;q21)/IGH-MALT1 translocation in MALT lymphomas contains templated nucleotide insertions and a major breakpoint region similar to follicular and mantle cell lymphoma.
Murga-Penas, E-M., Maria, E., Callet-Bauchu, E., Ye, H., Gazzo, S., Schilling, G., Schilling, G., Vettorazzi, E., Vettorazzi, E., Salles, G., Wlodarska, I., Bokemeyer, C., Dierlamm, J. & Dierlamm, J., 2009, In: BLOOD.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Thromboembolische Komplikationen - Prophylaxe und Therapie im Fokus
Langer, F., Holstein, K., Eifrig, B. & Bokemeyer, C., 2009, In: ONKOLOGE. 15, p. 150-156Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tissue factor procoagulant activity of plasma microparticles is increased in patients with early-stage prostate cancer.
Haubold, K., Rink, M., Spath, B., Friedrich, M., Chun, F., Marx, G., Amirkhosravi, A., Francis, J. L., Bokemeyer, C., Eifrig, B. & Langer, F., 2009, In: THROMB HAEMOSTASIS. 101, 6, p. 1147-1155 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Toward MSC in solid organ transplantation: 2008 position paper of the MISOT study group.
Dahlke, M. H., Hoogduijn, M., Eggenhofer, E., Popp, F. C., Renner, P., Slowik, P., Rosenauer, A., Piso, P., Geissler, E. K., Lange, C., Chabannes, D., Mazzanti, B., Bigenzahn, S., Bertolino, P., Kunter, U., Introna, M., Alessandro, R., Capelli, C., Perico, N., Casiraghi, F., Noris, M., Gotti, E., Seifert, M., Riccardo, S., Verspaget, H. W., van Hoek, B., Bartholomew, A., Wekerle, T., Volk, H. D., Remuzzi, G., Deans, R., Lazarus, H., Schlitt, H. J. & Baan, C. C., 2009, In: TRANSPLANTATION. 88, 5, p. 614-619 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Treatment patterns and outcomes in the management of anaemia in cancer patients in Europe: findings from the Anaemia Cancer Treatment (ACT) study.
Ludwig, H., Aapro, M., Bokemeyer, C., Macdonald, K., Soubeyran, P., Turner, M., Albrecht, T. & Abraham, I., 2009, In: EUR J CANCER. 45, 9, p. 1603-1615 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Unrelated donor stem cell transplantation in acquired severe aplastic anemia: a systematic review.
Peinemann, F., Grouven, U., Kröger, N., Pittler, M., Zschorlich, B. & Lange, S., 2009, In: HAEMATOLOGICA. 94, 12, p. 1732-1742 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ZM447439, a Novel Promising Aurora Kinase Inhibitor, Provokes Antiproliferative and Proapoptotic Effects Alone and in Combination with Bio- and Chemotherapeutic Agents in Gastroenteropancreatic Neuroendocrine Tumor Cell Lines.
Georgieva, I., Koychev, D., Wang, Y., Holstein, J., Hopfenmüller, W., Zeitz, M. & Grabowski, P., 2009, In: NEUROENDOCRINOLOGY.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Initial report on a phase I clinical trial: Prevention and treatment of post-operative Acute Kidney Injury with allogeneic Mesenchymal Stem Cells in patients who require on-pump cardiac surgery.
Gooch, A., Doty, J., Flores, J., Toegel, FE., Reiss, GR., Lange, C., Zander, AR., Zhang, P. & Westenfelder, C., 24.12.2008Research output: Other contribution › Net-publication - Articles in scientific forums or blogs › Research › peer-review
Analysis of sternotomy as treatment option for the resection of bilateral pulmonary metastases in pediatric solid tumors
Fuchs, J., Seitz, G., Ellerkamp, V., Dietz, K., Bosk, A., Müller, I., Warmann, S. W. & Schäfer, J. F., 12.2008, In: J SURG ONCOL. 17, 4, p. 323-30 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mesenchymal stem cell therapy for degenerative inflammatory disorders
Müller, I., Lymperi, S. & Dazzi, F., 12.2008, In: CURR OPIN ORGAN TRAN. 13, 6, p. 639-44 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Secretion of angiogenic proteins by human multipotent mesenchymal stromal cells and their clinical potential in the treatment of avascular osteonecrosis
Müller, I., Vaegler, M., Holzwarth, C., Tzaribatchev, N., Pfister, S. M., Schütt, B., Reize, P., Greil, J., Handgretinger, R. & Rudert, M., 11.2008, In: LEUKEMIA. 22, 11, p. 2054-61 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inhibitor-Immunology-Study. Different HLA-types seem to be involved in the inhibitor development in haemophilia A
Wieland, I., Wermes, C., Eifrig, B., Holstein, K., Pollmann, H., Siegmund, B., Bidlingmaier, C., Kurnik, K., Nimtz-Talaska, A., Niekrens, C., Eisert, R., Tiede, A., Ebenebe, C., Lakomek, M., Hoy, L., Welte, K. & Sykora, K-W., 10.2008, In: HAMOSTASEOLOGIE. 28, 1, p. 26-28 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Akt as a therapeutic target in cancer
Steelman, L. S., Stadelman, K. M., Chappell, W. H., Horn, S., Bäsecke, J., Cervello, M., Nicoletti, F., Libra, M., Stivala, F., Martelli, A. M. & McCubrey, J. A., 01.09.2008, In: EXPERT OPIN THER TAR. 12, 9, p. 1139-65 27 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
WT1 protein expression in slowly proliferating myeloid leukemic cell lines is scarce throughout the cell cycle with a minimum in G0/G1 phase
Kerst, G., Bergold, N., Viebahn, S., Gieseke, F., Kalinova, M., Trka, J., Handgretinger, R. & Müller, I., 09.2008, In: Leukemia research. 32, 9, p. 1393-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Drug delivery in acute myeloid leukemia
Kohlschütter, J., Michelfelder, S. & Trepel, M., 06.2008, In: EXPERT OPIN DRUG DEL. 5, 6, p. 653-63 11 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Radiation-induced HPRT mutations resulting from misrejoined DNA double-strand breaks
Rothkamm, K., Gunasekara, K., Warda, S. A., Krempler, A. & Löbrich, M., 06.2008, In: RADIAT RES. 169, 6, p. 639-48 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
WT1 protein expression in childhood acute leukemia
Kerst, G., Bergold, N., Gieseke, F., Coustan-Smith, E., Lang, P., Kalinova, M., Handgretinger, R., Trka, J. & Müller, I., 05.2008, In: AM J HEMATOL. 83, 5, p. 382-6 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Enhanced in vitro activation of immunocompetent cells in healthy individuals being subcutaneously 'vaccinated' with placebo (physiological saline)
Klein, R., Buck, S., Classen, K., Freiburg, C. F. C. & Huber, R., 03.2008, In: CLIN IMMUNOL. 126, 3, p. 322-31 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mesenchymal stromal cells: a novel treatment option for steroid-induced avascular osteonecrosis
Tzaribachev, N., Vaegler, M., Schaefer, J., Reize, P., Rudert, M., Handgretinger, R. & Müller, I., 03.2008, In: CAN MED ASSOC J. 10, 3, p. 232-4 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficient in vitro generation of adult multipotent cells from mobilized peripheral blood CD133+ cells
Kuçi, S., Kuçi, Z., Schmid, S., Seitz, G., Müller, I., Dufke, A., Leimig, T., Murti, G., Jurecic, R., Schumm, M., Lang, P., Bruchelt, G., Bader, P., Klingebiel, T., Niethammer, D. & Handgretinger, R., 02.2008, In: CELL PROLIFERAT. 41, 1, p. 12-27 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy
McCubrey, J. A., Sokolosky, M. L., Lehmann, B. D., Taylor, J. R., Navolanic, P. M., Chappell, W. H., Abrams, S. L., Stadelman, K. M., Wong, E. W. T., Misaghian, N., Horn, S., Bäsecke, J., Libra, M., Stivala, F., Ligresti, G., Tafuri, A., Milella, M., Zarzycki, M., Dzugaj, A., Chiarini, F., Evangelisti, C., Martelli, A. M., Terrian, D. M., Franklin, R. A. & Steelman, L. S., 01.01.2008, In: Advances in enzyme regulation. 48, p. 113-35 23 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review