Center for Oncology
Publications
- 2010
Y chromosome loss is a frequent early event in urothelial bladder cancer.
Minner, S. J. P., Kilgué, A., Stahl, P., Weikert, S., Rink, M., Dahlem, R., Fisch, M., Höppner, W., Wagner, W., Bokemeyer, C., Terracciano, L., Simon, R., Sauter, G. & Wilczak, W., 2010, In: PATHOLOGY. 42, 4, p. 356-359 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3- regulatory T cells suppressing autoimmune hepatitis
Kruse, N., Neumann, K., Schrage, A., Derkow, K., Schott, E., Erben, U., Kühl, A., Loddenkemper, C., Zeitz, M., Hamann, A. & Klugewitz, K., 12.2009, In: HEPATOLOGY. 50, 6, p. 1904-13 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bosutinib: a dual SRC/ABL kinase inhibitor for the treatment of chronic myeloid leukemia
Keller, G., Schafhausen, P. & Brummendorf, T. H., 01.10.2009, In: EXPERT REV HEMATOL. 2, 5, p. 489-97 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PKR activity is required for acute leukemic cell maintenance and growth: a role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation
Blalock, W. L., Grimaldi, C., Fala, F., Follo, M., Horn, S., Basecke, J., Martinelli, G., Cocco, L. & Martelli, A. M., 01.10.2009, In: J CELL PHYSIOL. 221, 1, p. 232-41 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Platelet derived bFGF mediates vascular integrative mechanisms of mesenchymal stem cells in vitro
Langer, H. F., Stellos, K., Steingen, C., Froihofer, A., Schönberger, T., Krämer, B., Bigalke, B., May, A. E., Seizer, P., Müller, I., Gieseke, F., Siegel-Axel, D., Meuth, S. G., Schmidt, A., Wendel, H. P., Müller, I., Bloch, W. & Gawaz, M., 08.2009, In: J MOL CELL CARDIOL. 47, 2, p. 315-25 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diffusion-driven device for a high-resolution dose-response profiling of combination chemotherapy
Ganser, A., Roth, G., van Galen, J. C., Hilderink, J., Wammes, J. J. G., Müller, I., van Leeuwen, F. N., Wiesmüller, K-H. & Brock, R., 01.07.2009, In: ANAL CHEM. 81, 13, p. 5233-40 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dendritic cells: functional aspects of glycosylation and lectins
Erbacher, A., Gieseke, F., Handgretinger, R. & Müller, I., 05.2009, In: HUM IMMUNOL. 70, 5, p. 308-12 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Drugs targeting integrins for cancer therapy
Binder, M. & Trepel, M., 03.2009, In: EXPERT OPIN DRUG DIS. 4, 3, p. 229-41 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Femoral bone tunnel placement using the transtibial tunnel or the anteromedial portal in ACL reconstruction: a radiographic evaluation
Dargel, J., Schmidt-Wiethoff, R., Fischer, S., Mader, K., Koebke, J. & Schneider, T., 03.2009, In: KNEE SURG SPORT TR A. 17, 3, p. 220-7 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Isolation of functionally distinct mesenchymal stem cell subsets using antibodies against CD56, CD271, and mesenchymal stem cell antigen-1
Battula, V. L., Treml, S., Bareiss, P. M., Gieseke, F., Roelofs, H., de Zwart, P., Müller, I., Schewe, B., Skutella, T., Fibbe, W. E., Kanz, L. & Bühring, H-J., 02.2009, In: HAEMATOLOGICA. 94, 2, p. 173-84 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[10 years of the Working Group for Geriatric Oncology of the DGHO/DGG/AIO]
Bokemeyer, C., 2009, In: ONKOLOGIE. 32, 3, p. 2 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
5-Azacytidine for the treatment of patients with acute myeloid leukemia or myelodysplastic syndrome who relapse after allo-SCT: a retrospective analysis.
Czibere, A., Bruns, I., Kröger, N., Platzbecker, U., Lind, J., Zohren, F., Fenk, R., Germing, U., Schröder, T., Gräf, T., Haas, R. & Kobbe, G., 2009, In: BONE MARROW TRANSPL. *45*, 5, p. 872-876 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity.
Spyridopoulos, I., Hoffmann, J., Aicher, A., Brümmendorf, T., Doerr, H. W., Zeiher, A. M. & Dimmeler, S., 2009, In: CIRCULATION. 120, 14, p. 1364-1372 14.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adeno-associated viral vectors and their redirection to cell-type specific receptors.
Michelfelder, S. & Trepel, M., 2009, In: ADV GENET. 67, p. 29-60Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adjuvante Therapie des Kolonkarzinoms
Schuch, G., Arnold, D. & Bokemeyer, C., 2009, In: ONKOLOGE. 15, p. 1215-1222Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A dose optimization method for electron radiotherapy using randomized aperture beams.
Engel, K. & Gauer, T., 2009, In: PHYS MED BIOL. 54, 17, p. 5253-5270 17.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer.
Trepel, M., Stoneham, C. A., Eleftherohorinou, H., Mazarakis, N. D., Pasqualini, R., Arap, W. & Hajitou, A., 2009, In: MOL CANCER THER. 8, 8, p. 2383-2391 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic hematopoietic stem cell transplantation (allo SCT) for chronic myeloid leukemia in the imatinib era: evaluation of its impact within a subgroup of the randomized German CML Study IV.
Saussele, S., Lauseker, M., Gratwohl, A., Beelen, D. W., Bunjes, D., Schwerdtfeger, R., Kolb, H-J., Ho, A. D., Falge, C., Holler, E., Schlimok, G., Zander, A. R., Arnold, R., Kanz, L., Dengler, R., Haferlach, C., Schlegelberger, B., Pfirrmann, M., Muller, M. C., Schnittger, S., Leitner, A., Pletsch, N., Hochhaus, A., Hasford, J. & Hehlmann, R., 2009, In: BLOOD. *115*, 10, p. 1880-1885 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation.
Kröger, N., Holler, E., Kobbe, G., Bornhäuser, M., Schwerdtfeger, R., Baurmann, H., Nagler, A., Bethge, W., Stelljes, M., Uharek, L., Wandt, H., Burchert, A., Corradini, P., Schubert, J., Kaufmann, M., Dreger, P., Wulf, G. G., Einsele, H., Zabelina, T., Kvasnicka, H. M., Thiele, J., Brand, R., Zander, A. R., Niederwieser, D., Witte, D. & Theo, M., 2009, In: BLOOD. 114, 26, p. 5264-5270 26.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Allogeneic stem cell transplantation for patients with refractory anaemia with matched related and unrelated donors: delay of the transplant is associated with inferior survival.
de Witte, T., Brand, R., van Biezen, A., Mufti, G., Ruutu, T., Finke, J., von Dem Borne, P., Vitek, A., Delforge, M., Alessandrino, P., Harlahakis, N., Russell, N., Martino, R., Verdonck, L., Kröger, N. & Niederwieser, D., 2009, In: BRIT J HAEMATOL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
AML with translocation t(8;16)(p11;p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features.
Haferlach, T., Kohlmann, A., Klein, H-U., Ruckert, C., Dugas, M., Williams, P. M., Kern, W., Schnittger, S., Bacher, U., Löffler, H. & Haferlach, C., 2009, In: LEUKEMIA. 23, 5, p. 934-943 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An open-label, Phase I study of cediranib (RECENTIN) in patients with acute myeloid leukemia.
Fiedler, W., Mesters, R., Heuser, M., Ehninger, G., Berdel, W. E., Zirrgiebel, U., Robertson, J. D., Puchalski, T. A., Collins, B., Jürgensmeier, J. M. & Serve, H., 2009, In: LEUKEMIA RES.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Antimyeloangiogenic therapy for cancer by inhibiting PlGF.
Loges, S., Schmidt, T. & Carmeliet, P., 2009, In: CLIN CANCER RES. 15, 11, p. 3648-3653 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Antitumor effects of polyclonal antithymocyte globulins: focus on B-cell malignancies and multiple myeloma.
Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 2009, In: ANN HEMATOL. 88, 5, p. 401-404 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A randomized phase III study comparing adjuvant 5-fluorouracil/folinic acid with FOLFIRI in patients following complete resection of liver metastases from colorectal cancer.
Ychou, M., Hohenberger, W., Thezenas, S., Navarro, M., Maurel, J., Bokemeyer, C., Shacham-Shmueli, E., Rivera, F., Kwok-Keung Choi, C. & Santoro, A., 2009, In: ANN ONCOL. 20, 12, p. 1964-1970 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A retrospective comparison of conventional intensity conditioning and reduced-intensity conditioning for allogeneic hematopoietic cell transplantation in myelofibrosis.
Gupta, V., Kröger, N., Aschan, J., Xu, W., Leber, B., Dalley, C., Sabloff, M., Lipton, J. H., Messner, H. & Brune, M., 2009, In: BONE MARROW TRANSPL.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Assembly and mobility of exon-exon junction complexes in living cells.
Schmidt, U., Im, K-B., Benzing, C., Janjetovic, S., Rippe, K., Lichter, P. & Wachsmuth, M., 2009, In: RNA. 15, 5, p. 862-876 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A systematic review on the clinical benefit and role of radiofrequency ablation as treatment of colorectal liver metastases.
Stang, A., Fischbach, R., Teichmann, W., Bokemeyer, C. & Braumann, D., 2009, In: EUR J CANCER. 45, 10, p. 1748-1756 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Aurora kinase inhibitor PHA-739358 suppresses growth of hepatocellular carcinoma in vitro and in a xenograft mouse model.
Benten, D., Keller, G., Quaas, A., Schrader, J., Gontarewicz, A., Balabanov, S., Balabanov, M., Wege, H., Moll, J., Lohse, A. W. & Brümmendorf, T., 2009, In: NEOPLASIA. 11, 9, p. 934-944 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Basic research and clinical applications of non-hematopoietic stem cells, 4-5 April 2008, Tubingen, Germany
Schäfer, R., Dominici, M., Müller, I., Horwitz, E., Asahara, T., Bulte, J. W. M., Bieback, K., Le Blanc, K., Bühring, H. J., Capogrossi, M. C., Dazzi, F., Gorodetsky, R., Henschler, R., Handgretinger, R., Kajstura, J., Kluger, P. J., Lange, C., Luettichau, I. V., Mertsching, H., Schrezenmeier, H., Sievert, K. D., Strunk, D., Verfaillie, C. & Northoff, H., 2009, In: CYTOTHERAPY. 11, 2, p. 245-55 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bevacizumab immune complexes activate platelets and induce thrombosis in FCGR2A transgenic mice.
Meyer, T., Robles-Carrillo, L., Robson, T., Langer, F., Desai, H., Davila, M., Amaya, M., Francis, J. L. & Amirkhosravi, A., 2009, In: J THROMB HAEMOST. 7, 1, p. 171-181 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biclonal expansion and heterogeneous lineage involvement in a case of chronic myeloproliferative disease with concurrent MPLW515L/JAK2V617F mutation.
Hussein, K., Bock, O., Theophile, K., Schlue, J., Ballmaier, M., Kröger, N., Göhring, G., Büsche, G. & Kreipe, H., 2009, In: BLOOD. 113, 6, p. 1391-1392 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone marrow mesenchymal stromal cells remain of recipient origin after allogeneic SCT and do not harbor the JAK2V617F mutation in patients with myelofibrosis.
Bacher, U., Asenova, S., Badbaran, A., Zander, A. R., Alchalby, H., Fehse, B., Kröger, N., Lange, C. & Ayuketang Ayuk, F., 2009, In: CLIN EXP MED.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Branching morphogenesis and antiangiogenesis candidates: tip cells lead the way.
Carmeliet, P., Frederik, D. S., Loges, S. & Mazzone, M., 2009, In: NAT REV CLIN ONCOL. 6, 6, p. 315-326 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer-testis antigens MAGE-C1/CT7 and MAGE-A3 promote the survival of multiple myeloma cells.
Atanackovic, D., Hildebrandt, Y., Jadczak, A., Cao, Y., Luetkens, T., Meyer, S., Kobold, S., Bartels, K., Pabst, C., Lajmi, N., Gordic, M., Stahl, T., Zander, A. R., Bokemeyer, C. & Kröger, N., 2009, In: HAEMATOLOGICA. *95*, 5, p. 785-793 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Catumaxomab - Antikörper-basierte intraperitoneale Therapie bei malignem Aszites
Bokemeyer, C. & Schuch, G., 2009, In: Arzneimittelther. 9, p. 264-270Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterisation of extramedullary relapse in patients with chronic myeloid leukemia in advanced disease after allogeneic stem cell transplantation.
Ocheni, S., Iwanski, G., Schafhausen, P., Zander, A. R., Ayuketang Ayuk, F., Klyuchnikov, E., Zabelina, T., Fiedler, W., Schnittger, S., Hochhaus, A., Brümmendorf, T., Kröger, N. & Bacher, U., 2009, In: LEUKEMIA LYMPHOMA. 50, 4, p. 551-558 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of 35 new cases with four different MPLW515 mutations and essential thrombocytosis or primary myelofibrosis.
Schnittger, S., Bacher, U., Haferlach, C., Beelen, D., Bojko, P., Bürkle, D., Dengler, R., Distelrath, A., Eckart, M., Eckert, R., Fries, S., Knoblich, J., Köchling, G., Laubenstein, H-P., Petrides, P., Planker, M., Pihusch, R., Weide, R., Kern, W. & Haferlach, T., 2009, In: HAEMATOLOGICA. 94, 1, p. 141-144 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chemotherapie-induzierte Kardiotoxizität
Oechsle, K. & Bokemeyer, C., 2009, Supportivtherapie in der Onkologie. Urban & Vogel, p. 62-71 10 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Colorectal carcinoma: the management of polyps, (neo)adjuvant therapy, and the treatment of metastases.
Schmiegel, W., Pox, C., Arnold, D., Porschen, R., Rödel, C., Reinacher-Schick, A., Germany, A. O. T. S. M. S. I., Aid, G. C., Society, G. C., Digestive, G. S. F., Diseases, M., General, G. S. F., Surgery, V., Hematology, G. S. F., Oncology, U., Pathology, G. S. F., Radiooncology, G. S. F., Society, G. R., Chemistry, G. J. S. F. C., Medicine, L., Coloproctology, G. S. F., Patients, A. O. S., Cancer, P. W. I., Disease, G. C., Association, U. C. & Medicine, G. S. F. I., 2009, In: DTSCH ARZTEBL INT. 106, 51-52, p. 843-848 51-52.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of the cytotoxicity of 4 preparations of anti-T-cell globulins in various hematological malignancies.
Ayuketang Ayuk, F., Maywald, N., Hannemann, S., Larsen, U., Zander, A. R. & Kröger, N., 2009, In: ANTICANCER RES. 29, 4, p. 1355-1360 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Concordance of assays designed for the quantification of JAK2V617F: a multicenter study.
Lippert, E., Girodon, F., Hammond, E., Jelinek, J., Reading, N. S., Fehse, B., Hanlon, K., Hermans, M., Richard, C., Swierczek, S., Ugo, V., Carillo, S., Harrivel, V., Marzac, C., Pietra, D., Sobas, M., Mounier, M., Migeon, M., Ellard, S., Kröger, N., Herrmann, R., Prchal, J. T., Skoda, R. C. & Hermouet, S., 2009, In: HAEMATOLOGICA. 94, 1, p. 38-45 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells.
Thoennissen, N. H., Iwanski, G., Doan, N. B., Okamoto, R., Lin, P., Abbassi, S., Song, J. H., Yin, D., Toh, M., Xie, W. D., Said, J. W. & Koeffler, H. P., 2009, In: CANCER RES. 69, 14, p. 5876-5884 14.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Current status and perspectives of tyrosine kinase inhibitor treatment in the post-transplant period in patients with chronic myeloid leukemia (CML).
Klyuchnikov, E., Kröger, N., Brümmendorf, T., Wiedemann, B., Zander, A. R. & Bacher, U., 2009, In: BIOL BLOOD MARROW TR.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Current status of gene expression profiling in the diagnosis and management of acute leukaemia.
Bacher, U., Kohlmann, A. & Haferlach, T., 2009, In: BRIT J HAEMATOL. 145, 5, p. 555-568 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Darbepoetin alfa for treating chemotherapy-induced anemia in patients with a baseline hemoglobin level <10 g/dL versus > or = 10 g/dL: an exploratory analysis from a randomized, double-blind, active-controlled trial.
Vansteenkiste, J., Hedenus, M., Gascon, P., Bokemeyer, C., Ludwig, H., Vermorken, J., Hamilton, L., Bridges, K. & Pujol, B., 2009, In: BMC CANCER. 9, p. 311Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Decrease of CD4(+)FOXP3(+) T regulatory cells in the peripheral blood of human subjects undergoing a mental stressor.
Freier, E., Weber, C. S., Nowottne, U., Horn, C., Bartels, K., Meyer, S., Hildebrandt, Y., Luetkens, T., Cao, Y., Pabst, C., Muzzulini, J., Schnee, B., Brunner-Weinzierl, M. C., Marangolo, M., Bokemeyer, C., Deter, H-C. & Atanackovic, D., 2009, In: PSYCHONEUROENDOCRINO.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deficiencies in the CD40 and CD154 receptor-ligand system reduce experimental lung metastasis.
Ingersoll, S. B., Langer, F., Walker, J. M., Meyer, T., Robson, T., Amaya, M., Desai, H., Francis, J. L. & Amirkhosravi, A., 2009, In: CLIN EXP METASTAS. 26, 7, p. 829-837 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of JAK2 exon 12 mutations in 15 patients with JAK2V617F negative polycythemia vera.
Schnittger, S., Bacher, U., Haferlach, C., Geer, T., Müller, P., Mittermüller, J., Petrides, P., Schlag, R., Sandner, R., Selbach, J., Slawik, H. R., Tessen, H. W., Wehmeyer, J., Kern, W. & Haferlach, T., 2009, In: HAEMATOLOGICA. 94, 3, p. 414-418 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Development of AML with t(8;21)(q22;q22) and RUNX1-RUNX1T1 fusion following Philadelphia-negative clonal evolution during treatment of CML with Imatinib.
Schafhausen, P., Dierlamm, J., Bokemeyer, C., Brümmendorf, T., Bacher, U., Zander, A. R., Schnittger, S. & Hochhaus, A., 2009, In: CANCER GENET-NY. 189, 1, p. 63-67 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review