An open-label, Phase I study of cediranib (RECENTIN) in patients with acute myeloid leukemia.

  • Walter Fiedler
  • Rolf Mesters
  • Michael Heuser
  • Gerhard Ehninger
  • Wolfgang E Berdel
  • Ute Zirrgiebel
  • Jane D Robertson
  • Tom A Puchalski
  • Barbara Collins
  • Juliane M Jürgensmeier
  • Hubert Serve

Related Research units

Abstract

VEGFR and c-Kit signaling pathways may contribute to the pathophysiology of acute myeloid leukemia (AML). Thirty-five patients with AML received cediranib (RECENTIN), an oral, highly potent VEGF signaling inhibitor with c-Kit activity, at doses of

Bibliographical data

Original languageGerman
ISSN0145-2126
Publication statusPublished - 2009
pubmed 19674789