Center for Oncology
Publications
- 2010
Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance.
Wermann, H., Stoop, H., Gillis, A. J. M., Honecker, F., Gurp, V., Ruud, J. H. L. M., Ammerpohl, O., Richter, J., Bokemeyer, C., Bokemeyer, C. & Looijenga, L. H. J., 2010, In: J PATHOL. 221, 4, p. 433-442 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heterogenous high-level HER-2 amplification in a small subset of colorectal cancers.
Marx, A., Burandt, E. C., Choschzick, M., Simon, R., Yekebas, E. F., Kaifi, J., Mirlacher, M., Atanackovic, D., Bokemeyer, C., Fiedler, W., Terracciano, L., Sauter, G. & Izbicki, J. R., 2010, In: HUM PATHOL. 41, 11, p. 1577-1585 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High dose chemotherapy as salvage treatment for unresectable late relapse germ cell tumors.
Lorch, A., Rick, O., Wündisch, T., Hartmann, J-T., Bokemeyer, C. & Beyer, J., 2010, In: J UROLOGY. 184, 1, p. 168-173 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Highly efficient lentiviral transduction of phenotypically and genotypically characterized endothelial progenitor cells from adult peripheral blood.
Stockschlaeder, M., Shardakova, O., Riecken, K., Stoldt, V. R., Fehse, B., Giers, G. & Scharf, R. E., 2010, In: BLOOD COAGUL FIBRIN. 21, 5, p. 464-473 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homogeneous EGFR amplification defines a subset of aggressive Barrett's adenocarcinomas with poor prognosis.
Marx, A., Zielinski, M., Kowitz, C-M., Dancau, A. M., Thieltges, S., Simon, R., Choschzick, M., Yekebas, E. F., Kaifi, J., Mirlacher, M., Atanackovic, D., Brümmendorf, T., Fiedler, W., Bokemeyer, C., Izbicki, J. R. & Sauter, G., 2010, In: HISTOPATHOLOGY. 57, 3, p. 418-426 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[HPV infection in head and neck squamous cell carcinoma (HNSCC). Highlights from ASCO 2010].
Ihloff, A-S., Knecht, R. & Tribius, S., 2010, In: HNO. 58, 12, p. 1163-1167 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human papilloma virus in locally advanced stage III/IV squamous cell cancer of the oropharynx and impact on choice of therapy.
Ihloff, A-S., Petersen, C., Hoffmann, M., Knecht, R. & Tribius, S., 2010, In: ORAL ONCOL. 46, 10, p. 705-711 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunohistochemistry and molecular analyses in myeloid sarcoma of the breast in a patient with relapse of NPM1-mutated and FLT3-mutated AML after allogeneic stem cell transplantation.
Choschzick, M., Bacher, U., Ayuketang Ayuk, F. & Lebeau, A., 2010, In: J CLIN PATHOL. 63, 6, p. 558-561 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor.
Wagner, K., Damm, F., Göhring, G., Görlich, K., Heuser, M., Schäfer, I., Ottmann, O., Lübbert, M., Heit, W., Kanz, L., Schlimok, G., Raghavachar, A. A., Fiedler, W., Kirchner, H. H., Brugger, W., Zucknick, M., Schlegelberger, B., Heil, G., Ganser, A. & Krauter, J., 2010, In: J CLIN ONCOL. 28, 14, p. 2356-2364 14.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Impact of JAK2V617F mutation status, allele burden, and clearance after allogeneic stem cell transplantation for myelofibrosis.
Alchalby, H., Badbaran, A., Zabelina, T., Kobbe, G., Hahn, J., Wolff, D., Bornhäuser, M., Christian, T., Baurmann, H., Bethge, W., Hildebrandt, Y., Bacher, U., Fehse, B., Zander, A. R. & Kröger, N., 2010, In: BLOOD. 116, 18, p. 3572-3581 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Induction chemotherapy before chemoradiotherapy and surgery for locally advanced rectal cancer : is it time for a randomized phase III trial?
Rödel, C., Arnold, D., Becker, H., Fietkau, R., Ghadimi, M., Graeven, U., Hess, C., Hofheinz, R., Hohenberger, W., Post, S., Raab, R., Sauer, R., Wenz, F. & Liersch, T., 2010, In: STRAHLENTHER ONKOL. 186, 12, p. 658-664 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influence on Busilvex pharmacokinetics of clonazepam compared to previous phenytoin historical data.
Carreras, E., Cahn, J. Y., Puozzo, C., Kröger, N., Sanz, G., Buzyn, A., Bacigalupo, A. & Vernant, J. P., 2010, In: ANTICANCER RES. 30, 7, p. 2977-2984 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
International Myeloma Working Group consensus statement regarding the current status of allogeneic stem-cell transplantation for multiple myeloma.
Lokhorst, H., Einsele, H., Vesole, D., Bruno, B., Jesus, S. M., Pérez-Simon, J. A., Kröger, N., Moreau, P., Gahrton, G., Gasparetto, C., Giralt, S. & Bensinger, W., 2010, In: J CLIN ONCOL. 28, 29, p. 4521-4530 29.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intramuscular manifestation of non-Hodgkin lymphoma and myeloma: prevalence, clinical signs, and computed tomography features.
Surov, A., Holzhausen, H-J., Arnold, D., Schmidt, J., Spielmann, R-P. & Behrmann, C., 2010, In: ACTA RADIOL. 51, 1, p. 47-51 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Introduction to the reports from the National Cancer Institute First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation.
Bishop, M. R., Alyea, E. P., Cairo, M. S., Falkenburg, J. H. F., June, C. H., Kröger, N., Little, R. F., Miller, J. S., Pavletic, S. Z., Porter, D., Riddell, S. R., van Besien, K., Wayne, A. S., Weisdorf, D. J., Wu, R. & Giralt, S., 2010, In: BIOL BLOOD MARROW TR. 16, 5, p. 563-564 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Isolated limb perfusion with melphalan for the treatment of intractable primary cutaneous diffuse large B-cell lymphoma leg type.
Kobold, S., Kilic, N., Luetkens, T., Bokemeyer, C. & Fiedler, W., 2010, In: ACTA HAEMATOL-BASEL. 123, 3, p. 179-181 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Keimzelltumore des Hodens
Oechsle, K., 2010, Therapiealgorithmen Onkologie. rs media GmbHResearch output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Lapatinib.
Schneider-Merck, T. & Trepel, M., 2010, In: Recent Results Cancer Res. 184, p. 45-59Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lenalidomide in patients with cisplatin-refractory and multiply relapsed germ cell tumors.
Oechsle, K., Bokemeyer, C. & Honecker, F., 2010, In: J CANCER RES CLIN. 136, 1, p. 165-167 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lessons learnt from gefitinib and erlotinib: Key insights into small-molecule EGFR-targeted kinase inhibitors in non-small cell lung cancer.
Laack, H-E., Sauter, G. & Bokemeyer, C., 2010, In: LUNG CANCER. 69, 3, p. 259-264 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Limited immune-modulating activity of porcine mesenchymal stromal cells abolishes their protective efficacy in acute kidney injury.
Brunswig-Spickenheier, B., Boche, J., Westenfelder, C., Peimann, F., Gruber, A. D., Jaquet, K., Krause, K., Zustin, J., Zander, A. R. & Lange, C., 2010, In: STEM CELLS DEV. 19, 5, p. 719-729 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-term follow-up of an intensified myeloablative conditioning regimen with in vivo T cell depletion followed by allografting in patients with advanced multiple myeloma.
Kröger, N., Einsele, H., Derigs, G., Wandt, H., Krüll, A. & Zander, A. R., 2010, In: BIOL BLOOD MARROW TR. 16, 6, p. 861-864 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer.
Minner, S. J. P., Jessen, B., Stiedenroth, L., Burandt, E. C., Köllermann, J., Mirlacher, M., Erbersdobler, A., Eichelberg, C., Fisch, M., Brümmendorf, T., Bokemeyer, C., Simon, R., Steuber, T., Graefen, M., Huland, H., Sauter, G. & Schlomm, T., 2010, In: CLIN CANCER RES. 16, 5, p. 1553-1560 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells
Holzwarth, C., Vaegler, M., Gieseke, F., Pfister, S. M., Handgretinger, R., Kerst, G. & Müller, I., 2010, In: BMC CELL BIOL. 11, p. 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation.
Vafaizadeh, V., Klemmt, P., Brendel, C., Riecken, K., Doebele, C., Britt, K., Grez, M., Fehse, B., Desriviéres, S. & Groner, B., 2010, In: STEM CELLS. 28, 5, p. 928-938 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Matched pair analysis comparing surgery followed by radiotherapy and radiotherapy alone for metastatic spinal cord compression.
Rades, D., Huttenlocher, S., Dunst, J., Bajrovic, A., Karstens, J. H., Rudat, V. & Schild, S. E., 2010, In: J CLIN ONCOL. 28, 22, p. 3597-3604 22.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Microcirculation of secondary bone tumors in vivo: the impact of minor surgery at a distal site.
Schäfer, C., Fuhrhop, I., Schröder, M., Viezens, L., Wellbrock, J., Fiedler, W., Rüther, W. & Hansen-Algenstaedt, N., 2010, In: J ORTHOP RES. 28, 11, p. 1515-1521 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mimicking the haematopoietic niche microenvironment provides a novel strategy for expansion of haematopoietic and megakaryocyte-progenitor cells from cord blood.
Deutsch, V., Hubel, E., Kay, S., Ohayon, T., Katz, B-Z., Many, A., Zander, A. R., Naparstek, E. & Grisaru, D., 2010, In: BRIT J HAEMATOL. 149, 1, p. 137-149 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis.
Gehling, U., Willems, M., Schlagner, K., Benndorf, R., Dandri-Petersen, M., Petersen, J., Sterneck, M., Pollok, J-M., Hossfeld, D. & Rogiers, X., 2010, In: WORLD J GASTROENTERO. 16, 2, p. 217-224 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular genetics in acute myeloid leukemia.
Bacher, U., Schnittger, S. & Haferlach, T., 2010, In: CURR OPIN ONCOL. 22, 6, p. 646-655 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management.
Kyle, R. A., Durie, B. G. M., Rajkumar, S. V., Landgren, O., Blade, J., Merlini, G., Kröger, N., Einsele, H., Vesole, D. H., Dimopoulos, M., San Miguel, J., Avet-Loiseau, H., Hajek, R., Chen, W. M., Anderson, K. C., Ludwig, H., Sonneveld, P., Pavlovsky, S., Palumbo, A., Richardson, P. G., Barlogie, B., Greipp, P., Vescio, R., Turesson, I., Westin, J., Boccadoro, M. & Group, I. M. W., 2010, In: LEUKEMIA. 24, 6, p. 1121-1127 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monte Carlo simulation of mini TEPC microdosimetric spectra: Influence of low energy electrons
Rollet, S., Colautti, P., Grosswendt, B., Moro, D., Gargioni, E., Conte, V. & DeNardo, L., 2010, In: RADIAT MEAS. 45, 10, p. 1330-1333 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1).
Falini, B., Macijewski, K., Weiss, T., Bacher, U., Schnittger, S., Kern, W., Kohlmann, A., Klein, H-U., Vignetti, M., Piciocchi, A., Fazi, P., Martelli, M. P., Vitale, A., Pileri, S., Miesner, M., Santucci, A., Haferlach, C., Mandelli, F. & Haferlach, T., 2010, In: BLOOD. 115, 18, p. 3776-3786 18.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multilineage dysplasia (MLD) in acute myeloid leukemia (AML) correlates with MDS-related cytogenetic abnormalities and a prior history of MDS or MDS/MPN but has no independent prognostic relevance: a comparison of 408 cases classified as "AML not otherwise specified" (AML-NOS) or "AML with myelodysplasia-related changes" (AML-MRC).
Miesner, M., Haferlach, C., Bacher, U., Weiss, T., Macijewski, K., Kohlmann, A., Klein, H-U., Dugas, M., Kern, W., Schnittger, S. & Haferlach, T., 2010, In: BLOOD. 116, 15, p. 2742-2751 15.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutations of the TET2 and CBL genes: novel molecular markers in myeloid malignancies.
Bacher, U., Haferlach, C., Schnittger, S., Kohlmann, A., Kern, W. & Haferlach, T., 2010, In: ANN HEMATOL. 89, 7, p. 643-652 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MUTYH-associated polyposis - variability of the clinical phenotype in patients with biallelic and monoallelic MUTYH mutations and report on novel mutations.
Morak, M., Laner, A., Bacher, U., Keiling, C. & Holinski-Feder, E., 2010, In: CLIN GENET. 78, 4, p. 353-363 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NCI first international workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on disease-specific methods and strategies for monitoring relapse following allogeneic stem cell transplantation. part II: chronic leukemias, myeloproliferative neoplasms, and lymphoid malignancies.
Kröger, N., Bacher, U., Bader, P., Böttcher, S., Borowitz, M. J., Dreger, P., Khouri, I., Olavarria, E., Radich, J., Stock, W., Vose, J. M., Weisdorf, D., Willasch, A., Giralt, S., Bishop, M. R. & Wayne, A. S., 2010, In: BIOL BLOOD MARROW TR. 16, 10, p. 1325-1346 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: report from the Committee on Disease-Specific Methods and Strategies for Monitoring Relapse following Allogeneic Stem Cell Transplantation. Part I: Methods, acute leukemias, and myelodysplastic syndromes.
Kröger, N., Bacher, U., Bader, P., Böttcher, S., Borowitz, M. J., Dreger, P., Khouri, I., Macapinlac, H. A., Macapintac, H., Olavarria, E., Radich, J., Stock, W., Vose, J. M., Weisdorf, D., Willasch, A., Giralt, S., Bishop, M. R. & Wayne, A. S., 2010, In: BIOL BLOOD MARROW TR. 16, 9, p. 1187-1211 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neue Wege der Stammzellforschung: Reprogrammierung von differenzierten Körperzellen
Beier, HM., Fehse, B., Friedrich, B., Götz, M., Hansmann, I., Hucho, F., Köchy, K., Müller-Röber, B., Rheinberger, HJ., Reich, J., Robpers, HH., Schöler, HR., Schöne-Seifert, B., Sperling, K., Tanner, K., Taupitz, J. & Wobus, AM., 2010, In: J Reprodmed Endokrinol. 7, p. 68-77Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Neurogenic transdifferentiation of human adipose-derived stem cells? A critical protocol reevaluation with special emphasis on cell proliferation and cell cycle alterations.
Kompisch, K. M., Lange, C., Steinemann, D., Skawran, B., Schlegelberger, B., Müller, R. & Schumacher, U., 2010, In: HISTOCHEM CELL BIOL. 134, 5, p. 453-468 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Optimizing the use of sunitinib in metastatic renal cell carcinoma: an update from clinical practice.
Schmidinger, M., Arnold, D., Szczylik, C., Wagstaff, J. & Ravaud, A., 2010, In: CANCER INVEST. 28, 8, p. 856-864 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Organprotektion in der Tumortherapie - mit Medikamenten vor unerwünschten Wirkungen schützen
Oechsle, K. & Bokemeyer, C., 2010, In: Im Fokus Onkologie. 12, p. 43-47Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Parenteral nutrition support for patients with pancreatic cancer. Results of a phase II study.
Pelzer, U., Arnold, D., Gövercin, M., Stieler, J., Doerken, B., Riess, H. & Oettle, H., 2010, In: BMC CANCER. 10, p. 86Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Patients with advanced non-seminomatous germ-cell tumour: the art of the start.
Honecker, F. & Bokemeyer, C., 2010, In: ANN ONCOL. 21, 8, p. 1569-1571 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Patterns of relapse after chemotherapy in patients with high-risk non-seminomatous germ cell tumor.
Oechsle, K., Lorch, A., Honecker, F., Kollmannsberger, C., Hartmann, J. T., Boehlke, I., Beyer, J. & Bokemeyer, C., 2010, In: ONCOLOGY-BASEL. 78, 1, p. 47-53 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Peptide length extension skews the minor HA-1 antigen presentation toward activated dendritic cells but reduces its presentation efficiency.
Hambach, L., Aghai, Z., Pool, J., Kröger, N. & Goulmy, E., 2010, In: J IMMUNOL. 185, 8, p. 4582-4589 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Peri-operative chemotherapy for the treatment of resectable liver metastases from colorectal cancer: A systematic review and meta-analysis of randomized trials.
Wieser, M., Sauerland, S., Arnold, D., Schmiegel, W. & Reinacher-Schick, A., 2010, In: BMC CANCER. 10, p. 309Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Phase I clinical and magnetic resonance imaging study of the vascular agent NGR-hTNF in patients with advanced cancers (European Organization for Research and Treatment of Cancer Study 16041).
Laarhoven, V., Fiedler, W., Fiedler, W., Desar, I. M. E., Asten, V., Jack, J. A., Marréaud, S., Lacombe, D., Govaerts, A-S., Bogaerts, J., Lasch, P., Timmer-Bonte, J. N. H., Lambiase, A., Bordignon, C., Punt, C. J. A., Heerschap, A., Herpen, V. & Carla, M. L., 2010, In: CLIN CANCER RES. 16, 4, p. 1315-1323 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pilot study of rituximab plus donor-lymphocyte infusion to prevent or treat relapse in B-cell lymphoma after allogeneic stem cell transplantation.
Cavattoni, I., Zabelina, T., Ayuketang Ayuk, F., Wolschke, C., Bacher, U., Zander, A. R. & Kröger, N., 2010, In: LEUKEMIA LYMPHOMA. 51, 1, p. 146-148 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Polymorphisms in genes of the steroid receptor superfamily modify postmenopausal breast cancer risk associated with menopausal hormone therapy
Abbas, S., Beckmann, L., Chang-Claude, J., Hein, R., Kropp, S., Parthimos, M., Dünnebier, T., Hamann, U., Brors, B., Eils, R., Zapatka, M., Brauch, H., Justenhoven, C., Flesch-Janys, D., Braendle, L-W., Brüning, T., Pesch, B., Spickenheuer, A., Baisch, C., Ko, YD. & Dahmen, N., 2010, In: INT J CANCER. 126, 12, p. 2935-2946 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review