Induction chemotherapy before chemoradiotherapy and surgery for locally advanced rectal cancer : is it time for a randomized phase III trial?
Abstract
in the era of preoperative chemoradiotherapy (CRT) and total mesorectal excision (TME), the development of distant metastases is the predominant mode of failure in rectal cancer patients today. Integrating more effective systemic therapy into combined modality programs is the challenge. The question that needs to be addressed is how and when to apply systemic treatment with adequate dose and intensity.
Bibliographical data
| Original language | German |
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| Article number | 12 |
| ISSN | 0179-7158 |
| Publication status | Published - 2010 |
| pubmed | 21136027 |
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