Center for Diagnostics
Publications
- 2013
Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma
Ben Batalla, I., Schultze, A., Wroblewski, M., Erdmann, R., Heuser, M., Waizenegger, J. S., Riecken, K., Binder, M., Schewe, D., Sawall, S., Witzke, V., Cubas Cordova, M., Janning, M., Wellbrock, J., Fehse, B., Hagel, C., Krauter, J., Ganser, A., Lorens, J. B., Fiedler, W., Carmeliet, P., Pantel, K., Bokemeyer, C. & Loges, S., 03.10.2013, In: BLOOD. 122, 14, p. 2443-52 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clofarabine in combination with pegylated asparaginase in the frontline treatment of childhood acute lymphoblastic leukaemia: a feasibility report from the CoALL 08-09 trial
Escherich, G., Zur Stadt, U., Zimmermann, M., Horstmann, M. A. & COALL study group, 01.10.2013, In: BRIT J HAEMATOL. 163, 2, p. 240-7 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Decreased frequency of CD73+CD8+ T cells of HIV-infected patients correlates with immune activation and T cell exhaustion
Tóth, I., Le, A. Q., Hartjen, P., Thomssen, A., Matzat, V., Lehmann, C., Scheurich, C., Beisel, C., Busch, C. P., Degen, O., Lohse, A. W., Eiermann, T., Fätkenheuer, G., Meyer-Olson, D., Bockhorn, M., Hauber, J., Lunzen, J. & Schulze Zur Wiesch, J., 01.10.2013, In: J LEUKOCYTE BIOL. 94, 4, p. 551-61 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunohistochemical analysis of p16 expression, HPV infection and its prognostic utility in oral squamous cell carcinoma
Gröbe, A., Hanken, H., Kluwe, L., Schöllchen, M., Tribius, S., Pohlenz, P., Clauditz, T., Grob, T., Simon, R., Sauter, G., Heiland, M. & Blessmann, M., 01.10.2013, In: J ORAL PATHOL MED. 42, 9, p. 676-81 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunological properties of extraembryonic human mesenchymal stromal cells derived from gestational tissue
Stubbendorff, M., Deuse, T., Hua, X., Phan, T. T., Bieback, K., Atkinson, K., Eiermann, T. H., Velden, J., Schröder, C., Reichenspurner, H., Robbins, R. C., Volk, H-D. & Schrepfer, S., 01.10.2013, In: STEM CELLS DEV. 22, 19, p. 2619-2629 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Infiltration of peritumoural but tumour-free parenchyma with IgG4-positive plasma cells in hilar cholangiocarcinoma and pancreatic adenocarcinoma
Resheq, Y. J., Quaas, A., von Renteln, D., Schramm, C., Lohse, A. W. & Lüth, S., 01.10.2013, In: DIGEST LIVER DIS. 45, 10, p. 859-65 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lymphatic invasion predicts survival in patients with early node-negative non-small cell lung cancer
Nentwich, M. F., Bohn, B. A., Uzunoglu, F. G., Reeh, M., Quaas, A., Grob, T. J., Perez, D., Kutup, A., Bockhorn, M., Izbicki, J. R. & Vashist, Y. K., 01.10.2013, In: J THORAC CARDIOV SUR. 146, 4, p. 781-7 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MALDI imaging on large-scale tissue microarrays identifies molecular features associated with tumour phenotype in oesophageal cancer
Quaas, A., Bahar, A. S., Loga, K., Seddiqi, A. S., Singer, J. M., Omidi, M., Kraus, O., Kwiatkowski, M., Trusch, M., Minner, S., Burandt, E., Stahl, P., Wilczak, W., Wurlitzer, M., Simon, R., Sauter, G., Marx, A. & Schlüter, H., 01.10.2013, In: HISTOPATHOLOGY. 63, 4, p. 455-62 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Micro-morphological properties of osteons reveal changes in cortical bone stability during aging, osteoporosis, and bisphosphonate treatment in women
Bernhard, A., Milovanovic, P., Zimmermann, E. A., Hahn, M., Djonic, D., Krause, M., Breer, S., Püschel, K., Djuric, M., Amling, M. & Busse, B., 01.10.2013, In: OSTEOPOROSIS INT. 24, 10, p. 2671-80 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Optimized immunohistochemistry in combination with image Analysis: a reliable alternative to quantitative ELISA determination of uPA and PAI-1 for routine risk group discrimination in breast cancer
Lang, D. S., Heilenkötter, U., Schumm, W., Behrens, O., Simon, R., Vollmer, E. & Goldmann, T., 01.10.2013, In: BREAST. 22, 5, p. 736-43 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Presence of the coxsackievirus and adenovirus receptor (CAR) in human neoplasms: a multitumour array analysis
Reeh, M., Bockhorn, M., Görgens, D., Vieth, M., Hoffmann, T., Simon, R., Izbicki, J. R., Sauter, G., Schumacher, U. & Anders, M., 01.10.2013, In: BRIT J CANCER. 109, 7, p. 1848-58 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation
Gieseke, F., Kruchen, A., Tzaribachev, N., Bentzien, F., Dominici, M. & Müller, I., 01.10.2013, In: EUR J IMMUNOL. 43, 10, p. 2741-9 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduced CD147 expression is linked to ERG fusion-positive prostate cancers but lacks substantial impact on PSA recurrence in patients treated by radical prostatectomy
Grupp, K., Höhne, T. S., Prien, K., Hube-Magg, C., Tsourlakis, M. C., Sirma, H., Pham, T., Heinzer, H., Graefen, M., Michl, U., Simon, R., Wilczak, W., Izbicki, J., Sauter, G., Minner, S., Schlomm, T. & Steurer, S., 01.10.2013, In: EXP MOL PATHOL. 95, 2, p. 227-34 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Subacute liver failure following anakinra treatment for adult-onset Still disease
Aly, L., Iking-Konert, C., Quaas, A. & Benten, D., 01.10.2013, In: J RHEUMATOL. 40, 10, p. 1775-7 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
X-linked inhibitor of apoptosis (XIAP) deficiency: the spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis
Speckmann, C., Lehmberg, K., Albert, M. H., Damgaard, R. B., Fritsch, M., Gyrd-Hansen, M., Rensing-Ehl, A., Vraetz, T., Grimbacher, B., Salzer, U., Fuchs, I., Ufheil, H., Belohradsky, B. H., Hassan, A., Cale, C. M., Elawad, M., Strahm, B., Schibli, S., Lauten, M., Kohl, M., Meerpohl, J. J., Rodeck, B., Kolb, R., Eberl, W., Soerensen, J., von Bernuth, H., Lorenz, M., Schwarz, K., zur Stadt, U. & Ehl, S., 01.10.2013, In: CLIN IMMUNOL. 149, 1, p. 133-41 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Infection and transmission dynamics of rKSHV.219 in primary endothelial cells
Jeffery, H. C., Wheat, R. L., Blackbourn, D. J., Nash, G. B. & Butler, L. M., 10.2013, In: J VIROL METHODS. 193, 1, p. 251-9 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke
Ludewig, P., Sedlacik, J., Gelderblom, M., Bernreuther, C., Korkusuz, Y., Wagener, C., Gerloff, C., Fiehler, J., Magnus, T. & Horst, A. K., 27.09.2013, In: CIRC RES. 113, 8, p. 1013-22 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DNA-Encoded Flagellin Activates Toll-Like Receptor 5 (TLR5), Nod-like Receptor Family CARD Domain-Containing Protein 4 (NRLC4), and Acts as an Epidermal, Systemic, and Mucosal-Adjuvant
Nyström, S., Bråve, A., Falkeborn, T., Devito, C., Rissiek, B., Johansson, D. X., Schröder, U., Uematsu, S., Akira, S., Hinkula, J. & Applequist, S., 25.09.2013, In: VACCINES-BASEL. 1, 4, p. 415-443Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies
Choe, C., Atzler, D., Wild, P. S., Carter, A. M., Böger, R. H., Ojeda Echevarria, F. M., Simova, O., Stockebrand, M., Lackner, K., Nabuurs, C., Marescau, B., Streichert, T., Müller, C., Lüneburg, N., De Deyn, P. P., Benndorf, R. A., Baldus, S., Gerloff, C., Blankenberg, S., Heerschap, A., Grant, P. J., Magnus, T., Zeller, T., Isbrandt, D. & Schwedhelm, E., 24.09.2013, In: CIRCULATION. 128, 13, p. 1451-61 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteocytic canalicular Networks: morphological implications for altered mechanosensitivity
Milovanovic, P., Zimmermann, E. A., Hahn, M., Djonic, D., Püschel, K., Djuric, M., Amling, M. & Busse, B., 24.09.2013, In: ACS NANO. 7, 9, p. 7542-51 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A retrospective evaluation of informed consent for tissue donation within a year of the donor's death
Wulff, B., Heinemann, A., Meins, S., Püschel, K. & Müller, K., 10.09.2013, In: FORENSIC SCI INT. 231, 1-3, p. 240-3 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells
Raczkowski, F., Ritter, J., Heesch, K., Schumacher, V., Guralnik, A., Höcker, L., Raifer, H., Klein, M., Bopp, T., Harb, H., Kesper, D. A., Pfefferle, P. I., Grusdat, M., Lang, P. A., Mittrücker, H-W. & Huber, M., 10.09.2013, In: P NATL ACAD SCI USA. 110, 37, p. 15019-24 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biomechanical evaluation of interlocking lag screw design in intramedullary nailing of unstable pertrochanteric fractures
Hoffmann, S., Paetzold, R., Stephan, D., Püschel, K., Buehren, V. & Augat, P., 01.09.2013, In: J ORTHOP TRAUMA. 27, 9, p. 483-90 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Differential regulation of marginal zone and follicular B cell responses by CD83
Uhde, M., Kuehl, S., Richardt, U., Fleischer, B. & Osterloh, A., 01.09.2013, In: INT IMMUNOL. 25, 9, p. 507-20 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased T helper type 17 response to pathogen stimulation in patients with primary sclerosing cholangitis
Katt, J., Schwinge, D., Schoknecht, T., Quaas, A., Sobottka, I., Burandt, E., Becker, C., Neurath, M. F., Lohse, A. W., Herkel, J. & Schramm, C., 01.09.2013, In: HEPATOLOGY. 58, 3, p. 1084-93 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Liver allograft pathology in healthy pediatric liver transplant recipients
Briem-Richter, A., Ganschow, R., Sornsakrin, M., Brinkert, F., Schirmer, J., Schäfer, H. & Grabhorn, E., 01.09.2013, In: PEDIATR TRANSPLANT. 17, 6, p. 543-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multigene Assays for Classification, Prognosis, and Prediction in Breast Cancer: a Critical Review on the Background and Clinical Utility
Sinn, P., Aulmann, S., Wirtz, R., Schott, S., Marmé, F., Varga, Z., Lebeau, A., Kreipe, H. & Schneeweiss, A., 01.09.2013, In: GEBURTSH FRAUENHEILK. 73, 9, p. 932-940 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Overexpression of the chromatin remodeler death-domain-associated protein in prostate cancer is an independent predictor of early prostate-specific antigen recurrence
Tsourlakis, M. C., Schoop, M., Plaß, C., Huland, H., Graefen, M., Steuber, T., Schlomm, T., Simon, R., Sauter, G., Sirma, H. & Minner, S., 01.09.2013, In: HUM PATHOL. 44, 9, p. 1789-96 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Plasma kallikrein the bradykinin-producing enzyme
Björkqvist, J., Jämsä, A. & Renné, T., 01.09.2013, In: THROMB HAEMOSTASIS. 110, 3, p. 399-407 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative vascular pathology and phenotyping familial and sporadic cerebral small vessel diseases
Craggs, L. J. L., Hagel, C., Kuhlenbaeumer, G., Borjesson-Hanson, A., Andersen, O., Viitanen, M., Kalimo, H., McLean, C. A., Slade, J. Y., Hall, R. A., Oakley, A. E., Yamamoto, Y., Deramecourt, V. & Kalaria, R. N., 01.09.2013, In: BRAIN PATHOL. 23, 5, p. 547-57 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion-positive prostate cancers
Krohn, A., Seidel, A., Burkhardt, L., Bachmann, F., Mader, M., Grupp, K., Eichenauer, T., Becker, A., Adam, M., Graefen, M., Huland, H., Kurtz, S., Steurer, S., Tsourlakis, M. C., Minner, S., Michl, U., Schlomm, T., Sauter, G., Simon, R. & Sirma, H., 01.09.2013, In: AM J PATHOL. 231, 1, p. 130-41 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Roles of endoproteolytic α-cleavage and shedding of the prion protein in neurodegeneration
Altmeppen, H. C., Prox, J., Puig Martorell, B., Dohler, F., Falker, C., Krasemann, S. & Glatzel, M., 01.09.2013, In: FEBS J. 280, 18, p. 4338-47 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Should we pay the student? A randomised trial of financial incentives in medical education
Raupach, T., Brown, J., Wieland, A., Anders, S. & Harendza, S., 01.09.2013, In: MED TEACH. 35, 9, p. 760-6 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The kallikreins: old proteases with new clinical potentials
Schmitt, M., Renné, T. & Scorilas, A., 01.09.2013, In: THROMB HAEMOSTASIS. 110, 3, p. 396-8 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Zinc-dependent contact system activation induces vascular leakage and hypotension in rodents
Björkqvist, J., Lecher, B., Maas, C. & Renné, T., 01.09.2013, In: BIOL CHEM. 394, 9, p. 1195-204 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Drebrin preserves endothelial integrity by stabilizing nectin at adherens junctions
Rehm, K., Panzer, L., van Vliet, V., Genot, E. & Linder, S., 15.08.2013, In: J CELL SCI. 126, Pt 16, p. 3756-69 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells
Itkonen, H. M., Minner, S., Guldvik, I. J., Sandmann, M. J., Tsourlakis, M. C., Berge, V., Svindland, A., Schlomm, T. & Mills, I. G., 15.08.2013, In: CANCER RES. 73, 16, p. 5277-87 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Magnetic resonance T1 relaxation time of venous thrombus is determined by iron processing and predicts susceptibility to lysis
Saha, P., Andia, M. E., Modarai, B., Blume, U., Humphries, J., Patel, A. S., Phinikaridou, A., Evans, C. E., Mattock, K., Grover, S. P., Ahmad, A., Lyons, O. T., Attia, R. Q., Renné, T., Premaratne, S., Wiethoff, A. J., Botnar, R. M., Schaeffter, T., Waltham, M. & Smith, A., 13.08.2013, In: CIRCULATION. 128, 7, p. 729-36 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein
Wolters, M., Boyle, C. E., Lardong, K., Trülzsch, K., Steffen, A., Rottner, K., Ruckdeschel, K. & Aepfelbacher, M., 09.08.2013, In: J BIOL CHEM. 288, 32, p. 23543-53 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancer
Werner, S., Frey, S., Riethdorf, S., Schulze, C., Alawi, M., Kling, L., Vafaizadeh, V., Sauter, G., Terracciano, L., Schumacher, U., Pantel, K. & Assmann, V., 09.08.2013, In: J BIOL CHEM. 288, 32, p. 22993-3008 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions
Prox, J., Bernreuther, C., Altmeppen, H., Grendel, J., Glatzel, M., D'Hooge, R., Stroobants, S., Ahmed, T., Balschun, D., Willem, M., Lammich, S., Isbrandt, D., Schweizer, M., Horré, K., De Strooper, B. & Saftig, P., 07.08.2013, In: J NEUROSCI. 33, 32, p. 12915-28, 12928aResearch output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Altered PTEN function caused by deletion or gene disruption is associated with poor prognosis in rectal but not in colon cancer
Bohn, B. A., Mina, S., Krohn, A., Simon, R., Kluth, M., Harasimowicz, S., Quaas, A., Bockhorn, M., Izbicki, J. R., Sauter, G., Marx, A. & Stahl, P. R., 01.08.2013, In: HUM PATHOL. 44, 8, p. 1524-33 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Analysis of cyclosporin a in hair samples from liver transplanted patients
Müller, A., Jungen, H., Iwersen-Bergmann, S., Sterneck, M. & Andresen-Streichert, H., 01.08.2013, In: THER DRUG MONIT. 35, 4, p. 450-8 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
cyp51A-Based mechanisms of Aspergillus fumigatus azole drug resistance present in clinical samples from Germany
Bader, O., Weig, M., Reichard, U., Lugert, R., Kuhns, M., Christner, M., Held, J., Peter, S., Schumacher, U., Buchheidt, D., Tintelnot, K., Groß, U. & MykoLabNet-D Partners, 01.08.2013, In: ANTIMICROB AGENTS CH. 57, 8, p. 3513-7 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling
Damgaard, R. B., Fiil, B. K., Speckmann, C., Yabal, M., zur Stadt, U., Bekker-Jensen, S., Jost, P. J., Ehl, S., Mailand, N. & Gyrd-Hansen, M., 01.08.2013, In: EMBO MOL MED. 5, 8, p. 1278-95 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
General practitioners and managing domestic violence: results of a qualitative study in Germany
Kohler, S., Höhne, A., Ehrhardt, M., Artus, J., Seifert, D. & Anders, S., 01.08.2013, In: J FORENSIC LEG MED. 20, 6, p. 732-5 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased osteoblast and osteoclast indices in individuals with systemic mastocytosis
Seitz, S., Barvencik, F., Koehne, T., Priemel, M., Pogoda, P., Semler, J., Minne, H., Pfeiffer, M., Zustin, J., Püschel, K., zu Eulenburg, C., Schinke, T. & Amling, M., 01.08.2013, In: OSTEOPOROSIS INT. 24, 8, p. 2325-34 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interleukin-22 is frequently expressed in small- and large-cell lung cancer and promotes growth in chemotherapy-resistant cancer cells
Kobold, S., Völk, S., Clauditz, T., Küpper, N. J., Minner, S., Tufman, A., Düwell, P., Lindner, M., Koch, I., Heidegger, S., Rothenfuer, S., Schnurr, M., Huber, R. M., Wilczak, W. & Endres, S., 01.08.2013, In: J THORAC ONCOL. 8, 8, p. 1032-42 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lack of association between CTLA-4 and PDCD1 polymorphisms and acute rejection in German liver transplant recipients
Thude, H., Schipler, A. D., Treszl, A., Peine, S., Koch, M., Sterneck, M. & Nashan, B., 01.08.2013, In: HUM IMMUNOL. 74, 8, p. 1041-5 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Physiology of ADP-ribosylation
Nolte, F. & Ziegler, M., 01.08.2013, In: FEBS J. 280, 15, p. 3483Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research