Center for Diagnostics
Publications
- 2015
De novo mTOR inhibitor based immunosuppression in ABO incompatible kidney transplantation
Koch, M., Wiech, T., Marget, M., Peine, S., Thude, H., Achilles, E. G., Fischer, L., Lehnhardt, A., Thaiss, F. & Nashan, B., 03.09.2015, In: CLIN TRANSPLANT.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nucleotide-Induced Membrane-Proximal Proteolysis Controls the Substrate Specificity of T Cell Ecto-ADP-Ribosyltransferase ARTC2.2
Menzel, S., Rissiek, B., Bannas, P., Jakoby, T., Miksiewicz, M., Schwarz, N., Nissen, M., Haag, F., Tholey, A. & Nolte, F., 01.09.2015, In: J IMMUNOL. 195, 5, p. 2057-2066Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A 19-Year-Old Male with an Intraventricular Tumor Disseminated anaplastic hemangiopericytoma WHO grade III/solitary fibrous tumor, cellular type
Krajewski, K. L., Matschke, J., Humke, N., Wolfgang, B., Westphal, M. & Schmidt, N. O., 09.2015, BRAIN PATHOLOGY. 657-658 ed. Vol. 25.Research output: SCORING: Contribution to book/anthology › Other › Research
Determination of Tumor Heterogeneity in Colorectal Cancers Using Heterogeneity Tissue Microarrays
Stahl, P. R., Schnellert, J., Koop, C., Simon, R., Marx, A., Izbicki, J. R., Sauter, G. & Quaas, A., 09.2015, In: PATHOL ONCOL RES. 21, 4, p. 1183-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of DNA ligase IV is linked to poor prognosis and characterizes a subset of prostate cancers harboring TMPRSS2:ERG fusion and PTEN deletion
Grupp, K., Roettger, L., Kluth, M., Hube-Magg, C., Simon, R., Lebok, P., Minner, S., Tsourlakis, M. C., Koop, C., Graefen, M., Adam, M., Haese, A., Wittmer, C., Sauter, G., Wilczak, W., Huland, H., Schlomm, T., Steurer, S. & Krech, T., 09.2015, In: Oncology reports. 34, 3, p. 1211-20 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High resolution structures of Plasmodium falciparum GST complexes provide novel insights into the dimer-tetramer transition and a novel ligand-binding site
Perbandt, M., Eberle, R., Fischer-Riepe, L., Cang, H., Liebau, E. & Betzel, C., 09.2015, In: J STRUCT BIOL. 191, 3, p. 365-75 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homozygosity for the common GAA gene splice site mutation c.-32-13T>G in Pompe disease is associated with the classical adult phenotypical spectrum
Musumeci, O., Thieme, A., Claeys, K. G., Wenninger, S., Kley, R. A., Kuhn, M., Lukacs, Z., Deschauer, M., Gaeta, M., Toscano, A., Gläser, D. & Schoser, B., 09.2015, In: NEUROMUSCULAR DISORD. 25, 9, p. 719-24 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hospital population screening reveals overrepresentation of CD5(-) monoclonal B-cell lymphocytosis and monoclonal gammopathy of undetermined significance of IgM type
Voigtländer, M., Vogler, B., Trepel, M., Panse, J., Jung, R., Bokemeyer, C., Bacher, U. & Binder, M., 09.2015, In: ANN HEMATOL. 94, 9, p. 1559-65 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Investigation of medical intervention with fatal outcome: the impact of post-mortem CT and CT angiography
Heinemann, A., Vogel, H., Heller, M., Tzikas, A. & Püschel, K., 09.2015, In: RADIOL MED. 120, 9, p. 835-45 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantitative proteomics unveiled: Regulation of DNA double strand break repair by EGFR involves PARP1
Myllynen, L., Kwiatkowski, M., Gleißner, L., Riepen, B., Hoffer, K., Wurlitzer, M., Petersen, C., Dikomey, E., Rothkamm, K., Schlüter, H. & Kriegs, M., 09.2015, In: RADIOTHER ONCOL. 116, 3, p. 423-30 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Response to cyclosporine in steroid-resistant nephrotic Syndrome: discontinuation is possible
Klaassen, I. A., Özgören, B., Sadowski, C. E., Möller, K., Van Husen, M., Lehnhardt, A., Timmermann, K., Freudenberg, F., Helmchen, U., Oh, J. & Kemper, M. J., 09.2015, In: PEDIATR NEPHROL. 30, 9, p. 1477-1483 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TH1 and TH17 cells promote crescent formation in experimental autoimmune glomerulonephritis
Hünemörder, S., Treder, J., Ahrens, S., Schumacher, V., Paust, H-J., Menter, T., Matthys, P., Kamradt, T., Meyer-Schwesinger, C., Panzer, U., Hopfer, H. & Mittrücker, H-W., 09.2015, In: J PATHOL. 237, 1, p. 62-71 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The aging prostate is never "normal": implications from the genomic characterization of multifocal prostate cancers
Schlomm, T., Weischenfeldt, J., Korbel, J. & Sauter, G., 09.2015, In: EUR UROL. 68, 3, p. 348-50 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The role of complement in C3 glomerulopathy
Zipfel, P. F., Skerka, C., Chen, Q., Wiech, T., Goodship, T., Johnson, S., Fremeaux-Bacchi, V., Nester, C., de Córdoba, S. R., Noris, M., Pickering, M. & Smith, R., 09.2015, In: MOL IMMUNOL. 67, 1, p. 21-30 10 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Vessel and Mast Cell Densities in Sporadic and Syndrome-associated Peripheral Nerve Sheath Tumors
Friedrich, R. E., Naber, U., Glatzel, M. & Hagel, C., 09.2015, In: ANTICANCER RES. 35, 9, p. 4713-22 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rat renal transplant model for mixed acute humoral and cellular rejection: Weak correlation of serum cytokines/chemokines with intragraft changes
Lemke, A., Noriega, M. D. L. M., Röske, A. M., Kemper, M. J., Nashan, B., Falk, C. S. & Koch, M., 20.08.2015, In: TRANSPL IMMUNOL. 33, 2, p. 95-102Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III
Björkqvist, J., de Maat, S., Lewandrowski, U., Di Gennaro, A., Oschatz, C., Schönig, K., Nöthen, M. M., Drouet, C., Braley, H., Nolte, M. W., Sickmann, A., Panousis, C., Maas, C. & Renné, T., 03.08.2015, In: J CLIN INVEST. 125, 8, p. 3132-46 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cytoplasmic Accumulation of Sequestosome 1 (p62) Is a Predictor of Biochemical Recurrence, Rapid Tumor Cell Proliferation, and Genomic Instability in Prostate Cancer
Burdelski, C., Reiswich, V., Hube-Magg, C., Kluth, M., Minner, S., Koop, C., Graefen, M., Heinzer, H., Tsourlakis, M. C., Wittmer, C., Huland, H., Simon, R., Schlomm, T., Sauter, G. & Steurer, S., 01.08.2015, In: CLIN CANCER RES. 21, 15, p. 3471-9 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Determination of ethyl glucuronide in hair for detection of alcohol consumption in patients after livertransplantation.
Andresen-Streichert, H., von Rothkirch, G., Vettorazzi, E., Müller, A., Lohse, A. W., Frederking, D., Seegers, B., Nashan, B. & Sterneck, M., 08.2015, In: THER DRUG MONIT. 37, 4, p. 539-545Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Foreign Body Abscess Mimicking a Malignant Peripheral Nerve Sheath Tumor in a Patient With Neurofibromatosis Type 1
Salamon, J., Hagel, C., Friedrich, R. E., Mautner, V-F. & Derlin, T., 08.2015, In: CLIN NUCL MED. 40, 8, p. 674-675Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection
Giersch, K., Allweiss, L., Volz, T., Helbig, M., Bierwolf, J., Lohse, A. W., Pollok, J. M., Petersen, J., Dandri-Petersen, M. & Lütgehetmann, M., 08.2015, In: J HEPATOL. 63, 2, p. 346-53 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Localization of SHH medulloblastoma in mice depends on the age at its initiation
Ohli, J., Neumann, J. E., Grammel, D. & Schüller, U., 08.2015, In: ACTA NEUROPATHOL. 130, 2, p. 307-9 3 p.Research output: SCORING: Contribution to journal › Newspaper articles › Transfer
Malignancy-associated haemophagocytic lymphohistiocytosis in children and adolescents
Lehmberg, K., Sprekels, B., Nichols, K. E., Woessmann, W., Müller, I., Suttorp, M., Bernig, T., Beutel, K., Bode, S. F. N., Kentouche, K., Kolb, R., Längler, A., Minkov, M., Schilling, F. H., Schmid, I., Vieth, S., Ehl, S., Zur Stadt, U. & Janka, G. E., 08.2015, In: BRIT J HAEMATOL. 170, 4, p. 539-49 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Relevance of chronic hepatitis E in liver transplant recipients: a real-life setting
Galante, A., Pischke, S., Polywka, S., Lütgehetmann, M., Suneetha, P. V., Gisa, A., Hiller, J., Dienes, H. P., Nashan, B., Lohse, A. W. & Sterneck, M., 08.2015, In: TRANSPL INFECT DIS. 17, 4, p. 617-22 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting the Gremlin-VEGFR2 axis - a promising strategy for multiple diseases?
Erdmann, R., Ozden, C., Weidmann, J. & Schultze, A., 08.2015, In: J PATHOL. 236, 4, p. 403-6 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion
Lin, Y-N., Bhuwania, R., Gromova, K., Failla, A. V., Lange, T., Riecken, K., Linder, S., Kneussel, M., Izbicki, J. R. & Windhorst, S., 30.07.2015, In: ONCOTARGET. 6, 21, p. 18577-89 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Combined Application of RGB Marking and Mass Spectrometric Imaging Facilitates Detection of Tumor Heterogeneity
Abramowski, P., Kraus, O., Rohn, S., Riecken, K., Fehse, B. & Schlüter, H., 03.07.2015, In: CANCER GENOM PROTEOM. 12, 4, p. 179-187 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RABGTPases in MT1-MMP trafficking and cell invasion:Physiology versus pathology
Linder, S. & Scita, G., 03.07.2015, In: Small GTPases. 6, 3, p. 145-52 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation
Itkonen, H. M., Engedal, N., Babaie, E., Luhr, M., Guldvik, I. J., Minner, S., Hohloch, J., Tsourlakis, M. C., Schlomm, T. & Mills, I. G., 01.07.2015, In: ONCOGENE. 34, 28, p. 3744-50Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence
Theiss, J. M., Günther, T., Alawi, M., Neumann, F., Tessmer, U., Fischer, N. & Grundhoff, A., 07.2015, In: PLOS PATHOG. 11, 7, p. e1004974Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clear cell papillary renal cell carcinoma and renal angiomyoadenomatous tumor two variants of a morphologic, immunohistochemical, and genetic distinct entity of renal cell carcinoma
Deml, K-F., Schildhaus, H-U., Compérat, E., von Teichman, A., Storz, M., Schraml, P., Bonventre, J. V., Fend, F., Fleige, B., Nerlich, A., Gabbert, H. E., GaBler, N., Grobholz, R., Hailemariam, S., Hinze, R., Knüchel, R., Lhermitte, B., Nesi, G., Rüdiger, T., Sauter, G. & Moch, H., 07.2015, In: AM J SURG PATHOL. 39, 7, p. 889-901 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of autochthonous and imported cases of hepatitis A or hepatitis E
Hartl, J., Kreuels, B., Polywka, S., Addo, M. M., Lütgehetmann, M., Dandri-Petersen, M., Dammermann, W., Sterneck, M., Lohse, A. W. & Pischke, S., 07.2015, In: Z GASTROENTEROL. 53, 7, p. 639-643Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples
Fischer, N., Indenbirken, D., Meyer, T., Lütgehetmann, M., Lellek, H., Spohn, M., Aepfelbacher, M., Alawi, M. & Grundhoff, A., 07.2015, In: J CLIN MICROBIOL. 53, 7, p. 2238-50 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hepatitis E Virus
Pauli, G., Aepfelbacher, M., Bauerfeind, U., Blümel, J., Burger, R., Gärtner, B., Gröner, A., Gürtler, L., Heiden, M., Hildebrandt, M., Jansen, B., Offergeld, R., Schlenkrich, U., Schottstedt, V., Seitz, R., Strobel, J., Willkommen, H. & Baylis, S. A., 07.2015, In: TRANSFUS MED HEMOTH. 42, 4, p. 247-65 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heterogeneity in D'Amico classification-based low-risk prostate cancer: Differences in upgrading and upstaging according to active surveillance eligibility
Schiffmann, J., Wenzel, P., Salomon, G., Budäus, L., Schlomm, T., Minner, S., Wittmer, C., Kraft, S., Krech, T., Steurer, S., Sauter, G., Beyer, B., Boehm, K., Tilki, D., Michl, U., Huland, H., Graefen, M. & Karakiewicz, P. I., 07.2015, In: UROL ONCOL-SEMIN ORI. 33, 7, p. 329.e13-9Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of a Novel Hepacivirus in Domestic Cattle from Germany
Fischer, N., Baechlein, C., Grundhoff, A., Alawi, M., Indenbirken, D., Postel, A., Baron, A. L., Offinger, J., Becker, K., Beineke, A., Rehage, J. & Becher, P., 07.2015, In: J VIROL. 89, 14, p. 7007-15 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PSMA expression is highly homogenous in primary prostate cancer
Tsourlakis, M. C., Klein, F., Kluth, M., Quaas, A., Graefen, M., Haese, A., Simon, R., Sauter, G., Schlomm, T. & Minner, S., 07.2015, In: APPL IMMUNOHISTO M M. 23, 6, p. 449-55 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Risk and timing of biochemical recurrence in pT3aN0/Nx prostate cancer with positive surgical margin - A multicenter study
Karl, A., Buchner, A., Tympner, C., Kirchner, T., Ganswindt, U., Belka, C., Ganzer, R., Wieland, W., Eder, F., Hofstädter, F., Schilling, D., Sievert, K-D., Stenzl, A., Scharpf, M., Fend, F., Vom Dorp, F., Rübben, H., Kurt Werner, S., Porres-Knoblauch, D., Heidenreich, A., Hangarter, B., Knüchel-Clarke, R., Rogenhofer, M., Wullich, B., Hartmann, A., Comploj, E., Pycha, A., Hanspeter, E., Pehrke, D., Sauter, G., Graefen, M., Gratzke, C., Stief, C., Wiegel, T. & Haese, A., 07.2015, In: RADIOTHER ONCOL. 116, 1, p. 119-24 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of panendoscopy in identifying and managing risk of head and neck squamous cell carcinoma in routine follow-up: a retrospective clinical evaluation
Münscher, A., Sehner, S., Taleh, J., Tribius, S., Möckelmann, N., Böttcher, A., Gulati, A., Dalchow, C., Clauditz, T. & Knecht, R., 07.2015, In: EUR ARCH OTO-RHINO-L. 272, 7, p. 1769-75 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeted screening for the detection of Pompe disease in patients with unclassified limb-girdle muscular dystrophy or asymptomatic hyperCKemia using dried blood: A Spanish cohort
Gutiérrez-Rivas, E., Bautista, J., Vílchez, J. J., Muelas, N., Díaz-Manera, J., Illa, I., Martínez-Arroyo, A., Olivé, M., Sanz, I., Arpa, J., Fernández-Torrón, R., López de Munáin, A., Jiménez, L., Solera, J. & Lukacs, Z., 07.2015, In: NEUROMUSCULAR DISORD. 25, 7, p. 548-53 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Impact of Tumor Diameter and Tumor Necrosis on Oncologic Outcomes in Patients With Urothelial Carcinoma of the Bladder Treated With Radical Cystectomy
Soave, A., John, L-M., Dahlem, R., Minner, S., Engel, O., Schmidt, S., Kluth, L. A., Fisch, M. & Rink, M., 07.2015, In: UROLOGY. 86, 1, p. 92-8 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The natural course of pT2 prostate cancer with positive surgical margin predicting biochemical recurrence
Karl, A., Buchner, A., Tympner, C., Kirchner, T., Ganswindt, U., Belka, C., Ganzer, R., Burger, M., Eder, F., Hofstädter, F., Schilling, D., Sievert, K., Stenzl, A., Scharpf, M., Fend, F., Vom Dorp, F., Rübben, H., Schmid, K., Porres-Knoblauch, D., Heidenreich, A., Hangarter, B., Knüchel-Clarke, R., Rogenhofer, M., Wullich, B., Hartmann, A., Comploj, E., Pycha, A., Hanspeter, E., Pehrke, D., Sauter, G., Graefen, M., Stief, C. & Haese, A., 07.2015, In: WORLD J UROL. 33, 7, p. 973-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Donor choice in haploidentical stem cell transplantation: fetal microchimerism is associated with better outcome in pediatric leukemia patients
Kruchen, A., Stahl, T., Gieseke, F., Binder, T. M. C., Özcan, Z., Meisel, R., Kreyenberg, H., Bader, P., Gruhn, B., Greil, J., Pfeiffer, M., Döring, M., Handgretinger, R., Fehse, B. & Müller, I., 22.06.2015, In: BONE MARROW TRANSPL. 50, 10, p. 1367-1370Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Extra- vs. intramedullary treatment of pertrochanteric fractures: a biomechanical in vitro study comparing dynamic hip screw and intramedullary nail
Weiser, L., Ruppel, A. A., Nüchtern, J. V., Sellenschloh, K., Zeichen, J., Püschel, K., Morlock, M. M. & Lehmann, W., 09.06.2015, In: ARCH ORTHOP TRAUM SU. 135, 8, p. 1101-1106Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biological Relevance and Therapeutic Potential of the Hypusine Modification System
Pallmann, N., Braig, M., Sievert, H., Preukschas, M., Hermans-Borgmeyer, I., Schweizer, M., Nagel, C. H., Neumann, M., Wild, P., Haralambieva, E., Hagel, C., Bokemeyer, C., Hauber, J. & Balabanov, S., 02.06.2015, In: J BIOL CHEM. 290, 30, p. 18343-18360Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient
Salzer, H. J. F., Rolling, T., Klupp, E-M. & Schmiedel, S., 01.06.2015, In: Med Mycol Case Rep. 8, p. 17-20Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
18F-FDG PET/CT for Detection of Leukemic Transformation in Myelofibrosis
Derlin, T., Clauditz, T. S. & Kröger, N., 06.2015, In: CLIN NUCL MED. 40, 6, p. 521-2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Albumin-associated free fatty acids induce macropinocytosis in podocytes
Chung, J-J., Huber, T. B., Gödel, M., Jarad, G., Hartleben, B., Kwoh, C., Keil, A., Karpitskiy, A., Hu, J., Huh, C. J., Cella, M., Gross, R. W., Miner, J. H. & Shaw, A. S., 06.2015, In: J CLIN INVEST. 125, 6, p. 2307-16 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Association of hepatitis E virus and essential cryoglobulinemia?
Pischke, S., Polywka, S., Haag, F., Iking-Konert, C., Sterneck, M., Lütgehetmann, M., Dammermann, W., Lüth, S. & Schirmer, J. H., 06.2015, In: J CLIN VIROL. 67, p. 23-24 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Highly divergent hepaciviruses from African cattle
Corman, V. M., Grundhoff, A., Baechlein, C., Fischer, N., Gmyl, A., Wollny, R., Dei, D., Ritz, D., Binger, T., Adankwah, E., Marfo, K. S., Annison, L., Annan, A., Adu-Sarkodie, Y., Oppong, S., Becher, P., Drosten, C. & Drexler, J. F., 06.2015, In: J VIROL. 89, 11, p. 5876-82 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review