Research ExplorerResearch UnitsDepartment of Pediatric Hematology and Oncology Publications

Department of Pediatric Hematology and Oncology

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Publications

  1. 2022

  2. Types of deviation and review criteria in pretreatment central quality control of tumor bed boost in medulloblastoma-an analysis of the German Radiotherapy Quality Control Panel in the SIOP PNET5 MB trial

    Dietzsch, S., Braesigk, A., Seidel, C., Remmele, J., Kitzing, R., Schlender, T., Mynarek, M., Geismar, D., Jablonska, K., Schwarz, R., Pazos, M., Weber, D. C., Frick, S., Gurtner, K., Matuschek, C., Harrabi, S. B., Glück, A., Lewitzki, V., Dieckmann, K., Benesch, M., Gerber, N. U., Obrecht, D., Rutkowski, S., Timmermann, B. & Kortmann, R-D., 03.2022, In: STRAHLENTHER ONKOL. 198, 3, p. 282-290 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Multimodal Treatment of Nasopharyngeal Carcinoma in Children, Adolescents and Young Adults-Extended Follow-Up of the NPC-2003-GPOH Study Cohort and Patients of the Interim Cohort

    Römer, T., Franzen, S., Kravets, H., Farrag, A., Makowska, A., Christiansen, H., Eble, M. J., Timmermann, B., Staatz, G., Mottaghy, F. M., Bührlen, M., Hagenah, U., Puzik, A., Driever, P. H., Greiner, J., Jorch, N., Tippelt, S., Schneider, D. T., Kropshofer, G., Overbeck, T. R., Christiansen, H., Brozou, T., Escherich, G., Becker, M., Friesenbichler, W., Feuchtinger, T., Puppe, W., Heussen, N., Hilgers, R. D. & Kontny, U., 28.02.2022, In: CANCERS. 14, 5, 1261.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Akute lymphoblastische Leukämie

    Escherich, G., Möricke, A., Horstmann, M. & Schrappe, M., 15.02.2022, Kompendium Internistische Onkologie: Standards in Diagnostik und Therapie. Schmoll, H-J. (ed.). 5 ed. Berlin, Heidelberg: Springer, 11 p.

    Research output: SCORING: Contribution to book/anthology › Chapter › Research › peer-review

  5. NET Release of Long-Term Surviving Neutrophils

    Kolman, J. P., Pagerols Raluy, L., Müller, I., Nikolaev, V., Trochimiuk, M., Appl, B., Wadehn, H., Dücker, C., Stoll, F., Boettcher, M., Reinshagen, K. & Trah, J., 15.02.2022, In: FRONT IMMUNOL. 13, p. 815412 815412.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Primary central nervous system sarcoma with DICER1 mutation-treatment results of a novel molecular entity in pediatric Peruvian patients

    Diaz Coronado, R. Y., Mynarek, M., Koelsche, C., Mora Alferez, P., Casavilca Zambrano, S., Wachtel Aptowitzer, A., Sahm, F., von Deimling, A., Schüller, U., Spohn, M., Sturm, D., Pfister, S. M., Morales La Madrid, A., Sernaque Quintana, R., Sarria Bardales, G., Negreiros Chinchihuara, T., Ojeda Medina, L., Garcia-Corrochano Medina, P., Campos Sanchez, D. A., Ponce Farfan, J., Rutkowski, S. & Garcia Leon, J. L., 15.02.2022, In: CANCER-AM CANCER SOC. 128, 4, p. 697-707 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma

    Lechner, M., Takahashi, Y., Turri-Zanoni, M., Liu, J., Counsell, N., Hermsen, M., Kaur, R. P., Zhao, T., Ramanathan, M., Schartinger, V. H., Emanuel, O., Helman, S., Varghese, J., Dudas, J., Riechelmann, H., Sprung, S., Haybaeck, J., Howard, D., Engel, N. W., Stewart, S., Brooks, L., Pickles, J. C., Jacques, T. S., Fenton, T. R., Williams, L., Vaz, F. M., O'Flynn, P., Stimpson, P., Wang, S., Hannan, S. A., Unadkat, S., Hughes, J., Dwivedi, R., Forde, C. T., Randhawa, P., Gane, S., Joseph, J., Andrews, P. J., Royle, G., Franchi, A., Maragliano, R., Battocchio, S., Bewicke-Copley, H., Pipinikas, C., Webster, A., Thirlwell, C., Ho, D., Teschendorff, A., Zhu, T., Steele, C. D., Pillay, N., Vanhaesebroeck, B., Mohyeldin, A., Fernandez-Miranda, J., Park, K. W., Le, Q-T., West, R. B., Saade, R., Manes, R. P., Omay, S. B., Vining, E. M., Judson, B. L., Yarbrough, W. G., Sansovini, M., Silvia, N., Grassi, I., Bongiovanni, A., Capper, D., Schüller, U., Thavaraj, S., Sandison, A., Surda, P., Hopkins, C., Ferrari, M., Mattavelli, D., Rampinelli, V., Facchetti, F., Nicolai, P., Bossi, P., Henriquez, O. A., Magliocca, K., Solares, C. A., Wise, S. K., Llorente, J. L., Patel, Z. M., Nayak, J. V., Hwang, P. H., Lacy, P. D., Woods, R., O'Neill, J. P., Jay, A., Carnell, D., Forster, M. D., Ishii, M., London, N. R., Bell, D. M., Gallia, G. L., Castelnuovo, P., Severi, S., Lund, V. J. & Hanna, E. Y., 02.2022, In: EUR J CANCER. 162, p. 221-236 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Final results of the Choroid Plexus Tumor study CPT-SIOP-2000

    Wolff, J. E., Van Gool, S. W., Kutluk, T., Diez, B., Kebudi, R., Timmermann, B., Garami, M., Sterba, J., Fuller, G. N., Bison, B. & Kordes, U. R., 02.2022, In: J NEURO-ONCOL. 156, 3, p. 599-613 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Gain-of-function variant p.Pro2555Arg of von Willebrand factor increases aggregate size through altering stem dynamics

    Huck, V., Chen, P-C., Xu, E-R., Tischer, A., Klemm, U., Aponte-Santamaría, C., Mess, C., Obser, T., Kutzki, F., König, G., Denis, C., Gräter, F., Wilmanns, M., Auton, M., Schneider, S. W., Schneppenheim, R., Hennig, J. & Brehm, M. A., 02.2022, In: THROMB HAEMOSTASIS. 122, 2, p. 226-239 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Hypersensitivity to Pegylated E.colia sparaginase as first-line treatment in contemporary paediatric acute lymphoblastic leukaemia protocols: a meta-analysis of the Ponte di Legno Toxicity working group

    Brigitha, L. J., Fiocco, M., Pieters, R., Albertsen, B. K., Escherich, G., Lopez-Lopez, E., Mondelaers, V., Vora, A., Vrooman, L., Schmiegelow, K., van der Sluis, I. M. & Ponte di Legno toxicity working group, 02.2022, In: EUR J CANCER. 162, p. 65-75 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Long-term survival of an adolescent glioblastoma patient under treatment with vinblastine and valproic acid illustrates importance of methylation profiling

    Kresbach, C., Bronsema, A., Guerreiro, H., Rutkowski, S., Schüller, U. & Winkler, B., 02.2022, In: CHILD NERV SYST. 38, 2, p. 479-483 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Maternal versus paternal living kidney transplant donation is associated with lower rejection in young pediatric recipients: A Collaborative Transplant Study report

    Engels, G., Döhler, B., Tönshoff, B., Oh, J., Kruchen, A., Müller, I. & Süsal, C., 02.2022, In: PEDIATR TRANSPLANT. 26, 1, e14154.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Local and Systemic Therapy of Recurrent Medulloblastomas in Children and Adolescents: Results of the P-HIT-REZ 2005 Study

    Gaab, C., Adolph, J. E., Tippelt, S., Mikasch, R., Obrecht, D., Mynarek, M., Rutkowski, S., Pfister, S. M., Milde, T., Witt, O., Bison, B., Warmuth-Metz, M., Kortmann, R-D., Dietzsch, S., Pietsch, T., Timmermann, B., Sträter, R., Bode, U., Faldum, A., Kwiecien, R. & Fleischhack, G., 18.01.2022, In: CANCERS. 14, 3, 471.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial

    Bailey, S., André, N., Gandola, L., Massimino, M., Rutkowski, S. & Clifford, S. C., 13.01.2022, In: CANCERS. 14, 2, 374.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  15. Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and high-dose chemotherapy within the prospective P-HIT trial

    Juhnke, B-O., Gessi, M., Gerber, N. U., Friedrich, C., Mynarek, M., von Bueren, A. O., Haberler, C., Schüller, U., Kortmann, R-D., Timmermann, B., Bison, B., Warmuth-Metz, M., Kwiecien, R., Pfister, S. M., Spix, C., Pietsch, T., Kool, M., Rutkowski, S. & von Hoff, K., 05.01.2022, In: NEURO-ONCOLOGY. 24, 1, p. 127-137 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

    Das, A., Sudhaman, S., Morgenstern, D., Coblentz, A., Chung, J., Stone, S. C., Alsafwani, N., Liu, Z. A., Karsaneh, O. A. A., Soleimani, S., Ladany, H., Chen, D., Zatzman, M., Cabric, V., Nobre, L., Bianchi, V., Edwards, M., Sambira Nahum, L. C., Ercan, A. B., Nabbi, A., Constantini, S., Dvir, R., Yalon-Oren, M., Campino, G. A., Caspi, S., Larouche, V., Reddy, A., Osborn, M., Mason, G., Lindhorst, S., Bronsema, A., Magimairajan, V., Opocher, E., De Mola, R. L., Sabel, M., Frojd, C., Sumerauer, D., Samuel, D., Cole, K., Chiaravalli, S., Massimino, M., Tomboc, P., Ziegler, D. S., George, B., Van Damme, A., Hijiya, N., Gass, D., McGee, R. B., Mordechai, O., Bowers, D. C., Laetsch, T. W., Lossos, A., Blumenthal, D. T., Sarosiek, T., Yen, L. Y., Knipstein, J., Bendel, A., Hoffman, L. M., Luna-Fineman, S., Zimmermann, S., Scheers, I., Nichols, K. E., Zapotocky, M., Hansford, J. R., Maris, J. M., Dirks, P., Taylor, M. D., Kulkarni, A. V., Shroff, M., Tsang, D. S., Villani, A., Xu, W., Aronson, M., Durno, C., Shlien, A., Malkin, D., Getz, G., Maruvka, Y. E., Ohashi, P. S., Hawkins, C., Pugh, T. J., Bouffet, E. & Tabori, U., 01.2022, In: NAT MED. 28, 1, p. 125-135 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD

    Arnold, D. E., Nofal, R., Wakefield, C., Lehmberg, K., Wustrau, K., Albert, M. H., Morris, E. C., Heimall, J. R., Bunin, N. J., Kumar, A., Jordan, M. B., Cole, T., Choo, S., Brettig, T., Speckmann, C., Ehl, S., Salamonowicz, M., Wahlstrom, J., Rao, K., Booth, C., Worth, A. & Marsh, R. A., 01.2022, In: J CLIN IMMUNOL. 42, 1, p. 36-45 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity

    Groß, M., Speckmann, C., May, A., Gajardo-Carrasco, T., Wustrau, K., Maier, S. L., Panning, M., Huzly, D., Agaimy, A., Bryceson, Y. T., Choo, S., Chow, C. W., Dückers, G., Fasth, A., Fraitag, S., Gräwe, K., Haxelmans, S., Holzinger, D., Hudowenz, O., Hübschen, J. M., Khurana, C., Kienle, K., Klifa, R., Korn, K., Kutzner, H., Lämmermann, T., Ledig, S., Lipsker, D., Meeths, M., Naumann-Bartsch, N., Rascon, J., Schänzer, A., Seidl, M., Tesi, B., Vauloup-Fellous, C., Vollmer-Kary, B., Warnatz, K., Wehr, C., Neven, B., Vargas, P., Sepulveda, F. E., Lehmberg, K., Schmitt-Graeff, A. & Ehl, S., 01.2022, In: J ALLERGY CLIN IMMUN. 149, 1, p. 388-399.e4

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. 2021

  20. Relapsed Medulloblastoma in Pre-Irradiated Patients: Current Practice for Diagnostics and Treatment

    Hill, R. M., Plasschaert, S. L. A., Timmermann, B., Dufour, C., Aquilina, K., Avula, S., Donovan, L., Lequin, M., Pietsch, T., Thomale, U., Tippelt, S., Wesseling, P., Rutkowski, S., Clifford, S. C., Pfister, S. M., Bailey, S. & Fleischhack, G., 28.12.2021, In: CANCERS. 14, 1, 126.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  21. Ex vivo testis explant culture of human testicular tissue

    Aden, N. L., Soave, A., Kordes, U., Bleeke, M., Salzbrunn, A. & von Kopylow, K., 05.12.2021, In: J Reprodmed Endokrinol. 2020, 17 (Supplementum 1), 39-40

    Research output: SCORING: Contribution to journal › Conference abstract in journal › Research

  22. SIOP PNET5 MB Trial: History and Concept of a Molecularly Stratified Clinical Trial of Risk-Adapted Therapies for Standard-Risk Medulloblastoma

    Mynarek, M., Milde, T., Padovani, L., Janssens, G. O., Kwiecien, R., Mosseri, V., Clifford, S. C., Doz, F. & Rutkowski, S., 02.12.2021, In: CANCERS. 13, 23, 1677.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  23. Dose-adjusted EPOCH-rituximab or intensified B-NHL therapy for pediatric primary mediastinal large B-cell lymphoma

    Knörr, F., Zimmermann, M., Attarbaschi, A., Kabickova, E., Maecker-Kolhoff, B., Ruf, S., Kühnle, I., Ebinger, M., Garthe, A-K., Simonitsch-Klupp, I., Oschlies, I., Klapper, W., Burkhardt, B. & Wößmann, W., 01.12.2021, In: HAEMATOLOGICA. 106, 12, p. 3232-3235 4 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  24. Clinical evidence for a biological effect of epigenetically active decitabine in relapsed or progressive rhabdoid tumors

    Steinbügl, M., Nemes, K., Johann, P., Kröncke, T., Tüchert, S., da Costa, M. J. G., Ebinger, M., Schüller, U., Sehested, A., Hauser, P., Reinhard, H., Sumerauer, D., Hettmer, S., Jakob, M., Hasselblatt, M., Siebert, R., Witt, O., Gerss, J., Kerl, K. & Frühwald, M. C., 12.2021, In: PEDIATR BLOOD CANCER. 68, 12, e29267.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Double adenomas of the pituitary reveal distinct lineage markers, copy number alterations, and epigenetic profiles

    Hagel, C., Schüller, U., Flitsch, J., Knappe, U. J., Kellner, U., Bergmann, M., Buslei, R., Buchfelder, M., Rüdiger, T., Herms, J. & Saeger, W., 12.2021, In: PITUITARY. 24, 6, p. 904-913 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Co-activation of Sonic hedgehog and Wnt signaling in murine retinal precursor cells drives ocular lesions with features of intraocular medulloepithelioma

    Dottermusch, M., Sumisławski, P., Krevet, J., Middelkamp, M., Voß, H., Siebels, B., Bartsch, H., Sotlar, K., Meyer, P., Frank, S., Korshunov, A., Glatzel, M., Schüller, U. & Neumann, J. E., 16.11.2021, In: ONCOGENESIS. 10, 11, p. 78

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Insights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles

    Schoennagel, B. P., Müllerleile, K., Tahir, E., Starekova, J., Grosse, R., Yamamura, J., Bannas, P., Adam, G. & Fischer, R., 03.11.2021, In: INSIGHTS IMAGING. 12, 1, 159.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. EXTH-70. ESTABLISHMENT OF INTRAVENTRICULAR SHH INHIBITION AS A THERAPEUTIC OPTION IN YOUNG PATIENTS WITH MEDULLOBLASTOMA

    Kresbach, C., Schoof, M., Leven, T., Holst, L., Yorgan, T. A., Wrzeszcz, A., Rutkowski, S. J. & Schüller, U., 11.2021, In: NEURO-ONCOLOGY. 23, Supplement_6, p. vi179

    Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review

  29. Hematopoietic stem cell transplantation in children and adolescents with GATA2-related myelodysplastic syndrome

    Bortnick, R., Wlodarski, M., de Haas, V., De Moerloose, B., Dworzak, M., Hasle, H., Masetti, R., Starý, J., Turkiewicz, D., Ussowicz, M., Kozyra, E., Albert, M., Bader, P., Bordon, V., Cario, G., Beier, R., Schulte, J., Bresters, D., Müller, I., Pichler, H., Sedlacek, P., Sauer, M. G., Zecca, M., Göhring, G., Yoshimi, A., Noellke, P., Erlacher, M., Locatelli, F., Niemeyer, C. M. & Strahm, B., 11.2021, In: BONE MARROW TRANSPL. 56, 11, p. 2732-2741 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Initial presenting manifestations in 16,486 patients with inborn errors of immunity include infections and noninfectious manifestations

    Thalhammer, J., Kindle, G., Nieters, A., Rusch, S., Seppänen, M. R. J., Fischer, A., Grimbacher, B., Edgar, D., Buckland, M., Mahlaoui, N., Ehl, S. & European Society for Immunodeficiencies Registry Working Party, 11.2021, In: J ALLERGY CLIN IMMUN. 148, 5, p. 1332-1341.e5 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Molecular features of non-anaplastic peripheral T-cell lymphoma in children and adolescents

    Au-Yeung, R. K. H., Richter, J., Iaccarino, I., Abramov, D., Bacon, C. M., Balagué, O., d'Amore, E. S. G., Simonitsch-Klupp, I., Hebeda, K., Nakazawa, A., Oschlies, I., Kontny, U., Woessmann, W., Burkhardt, B. & Klapper, W., 11.2021, In: PEDIATR BLOOD CANCER. 68, 11, e29285.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas

    Kirches, E., Sahm, F., Korshunov, A., Bluecher, C., Waldt, N., Kropf, S., Schrimpf, D., Sievers, P., Stichel, D., Schüller, U., Schittenhelm, J., Riemenschneider, M. J., Karajannis, M. A., Perry, A., Pietsch, T., Boekhoff, S., Capper, D., Beck, K., Paramasivam, N., Schlesner, M., Brastianos, P. K., Müller, H. L., Pfister, S. M. & Mawrin, C., 11.2021, In: ACTA NEUROPATHOL. 142, 5, p. 873-886 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Recommendations for Diagnosis and Treatment of Children with Transient Abnormal Myelopoiesis (TAM) and Myeloid Leukemia in Down Syndrome (ML-DS)

    Al-Kershi, S., Golnik, R., Flasinski, M., Waack, K., Rasche, M., Creutzig, U., Dworzak, M., Reinhardt, D. & Klusmann, J-H., 11.2021, In: KLIN PADIATR. 233, 6, p. 267-277 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

    Sievers, P., Henneken, S. C., Blume, C., Sill, M., Schrimpf, D., Stichel, D., Okonechnikov, K., Reuss, D. E., Benzel, J., Maaß, K. K., Kool, M., Sturm, D., Zheng, T., Ghasemi, D. R., Kohlhof-Meinecke, P., Cruz, O., Suñol, M., Lavarino, C., Ruf, V., Boldt, H. B., Pagès, M., Pouget, C., Schweizer, L., Kranendonk, M. E. G., Akhtar, N., Bunkowski, S., Stadelmann, C., Schüller, U., Mueller, W. C., Dohmen, H., Acker, T., Harter, P. N., Mawrin, C., Beschorner, R., Brandner, S., Snuderl, M., Abdullaev, Z., Aldape, K., Gilbert, M. R., Armstrong, T. S., Ellison, D. W., Capper, D., Ichimura, K., Reifenberger, G., Grundy, R. G., Jabado, N., Krskova, L., Zapotocky, M., Vicha, A., Varlet, P., Wesseling, P., Rutkowski, S., Korshunov, A., Wick, W., Pfister, S. M., Jones, D. T. W., von Deimling, A., Pajtler, K. W. & Sahm, F., 11.2021, In: ACTA NEUROPATHOL. 142, 5, p. 827-839 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Second Paediatric Strategy Forum for anaplastic lymphoma kinase (ALK) inhibition in paediatric malignancies: ACCELERATE in collaboration with the European Medicines Agency with the participation of the Food and Drug Administration

    Pearson, A. D. J., Barry, E., Mossé, Y. P., Ligas, F., Bird, N., de Rojas, T., Zimmerman, Z. F., Wilner, K., Woessmann, W., Weiner, S., Weigel, B., Venkatramani, R., Valteau, D., Trahair, T., Smith, M., Singh, S., Selvaggi, G., Scobie, N., Schleiermacher, G., Richardson, N., Park, J., Nysom, K., Norga, K., Merino, M., McDonough, J., Matloub, Y., Marshall, L. V., Lowe, E., Lesa, G., Irwin, M., Karres, D., Gajjar, A., Doz, F., Fox, E., DuBois, S. G., Donoghue, M., Casanova, M., Caron, H., Buenger, V., Bradford, D., Blanc, P., Barone, A., Reaman, G. & Vassal, G., 11.2021, In: EUR J CANCER. 157, p. 198-213 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  36. Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia

    Zielen, S., Duecker, R. P., Woelke, S., Donath, H., Bakhtiar, S., Buecker, A., Kreyenberg, H., Huenecke, S., Bader, P., Mahlaoui, N., Ehl, S., El-Helou, S. M., Pietrucha, B., Plebani, A., van der Flier, M., van Aerde, K., Kilic, S. S., Reda, S. M., Kostyuchenko, L., McDermott, E., Galal, N., Pignata, C., Pérez, J. L. S., Laws, H-J., Niehues, T., Kutukculer, N., Seidel, M. G., Marques, L., Ciznar, P., Edgar, J. D. M., Soler-Palacín, P., von Bernuth, H., Krueger, R., Meyts, I., Baumann, U., Kanariou, M., Grimbacher, B., Hauck, F., Graf, D., Granado, L. I. G., Prader, S., Reisli, I., Slatter, M., Rodríguez-Gallego, C., Arkwright, P. D., Bethune, C., Deripapa, E., Sharapova, S. O., Lehmberg, K., Davies, E. G., Schuetz, C., Kindle, G. & Schubert, R., 11.2021, In: J CLIN IMMUNOL. 41, 8, p. 1878-1892 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies

    Adolph, J. E., Fleischhack, G., Gaab, C., Mikasch, R., Mynarek, M., Rutkowski, S., Schüller, U., Pfister, S. M., Pajtler, K. W., Milde, T., Witt, O., Bison, B., Warmuth-Metz, M., Kortmann, R-D., Dietzsch, S., Pietsch, T., Timmermann, B., Tippelt, S. & German GPOH HIT-Network, 11.2021, In: J NEURO-ONCOL. 155, 2, p. 193-202 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma

    Bočkaj, I., Martini, T. E. I., de Camargo Magalhães, E. S., Bakker, P. L., Meeuwsen-de Boer, T. G. J., Armandari, I., Meuleman, S. L., Mondria, M. T., Stok, C., Kok, Y. P., Bakker, B., Wardenaar, R., Seiler, J., Broekhuis, M. J. C., van den Bos, H., Spierings, D. C. J., Ringnalda, F. C. A., Clevers, H., Schüller, U., van Vugt, M. A. T. M., Foijer, F. & Bruggeman, S. W. M., 11.2021, In: PLOS GENET. 17, 11, e1009868.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets

    van Tilburg, C. M., Pfaff, E., Pajtler, K. W., Langenberg, K. P. S., Fiesel, P., Jones, B. C., Balasubramanian, G. P., Stark, S., Johann, P. D., Blattner-Johnson, M., Schramm, K., Dikow, N., Hirsch, S., Sutter, C., Grund, K., von Stackelberg, A., Kulozik, A. E., Lissat, A., Borkhardt, A., Meisel, R., Reinhardt, D., Klusmann, J-H., Fleischhack, G., Tippelt, S., von Schweinitz, D., Schmid, I., Kramm, C. M., von Bueren, A. O., Calaminus, G., Vorwerk, P., Graf, N., Westermann, F., Fischer, M., Eggert, A., Burkhardt, B., Wößmann, W., Nathrath, M., Hecker-Nolting, S., Frühwald, M. C., Schneider, D. T., Brecht, I. B., Ketteler, P., Fulda, S., Koscielniak, E., Meister, M. T., Scheer, M., Hettmer, S., Schwab, M., Tremmel, R., Øra, I., Hutter, C., Gerber, N. U., Lohi, O., Kazanowska, B., Kattamis, A., Filippidou, M., Goemans, B., Zwaan, C. M., Milde, T., Jäger, N., Wolf, S., Reuss, D., Sahm, F., von Deimling, A., Dirksen, U., Freitag, A., Witt, R., Lichter, P., Kopp-Schneider, A., Jones, D. T. W., Molenaar, J. J., Capper, D., Pfister, S. M. & Witt, O., 11.2021, In: CANCER DISCOV. 11, 11, p. 2764-2779 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Recommendations for Age-Appropriate Testing, Timing, and Frequency of Audiologic Monitoring During Childhood Cancer Treatment: An International Society of Paediatric Oncology Supportive Care Consensus Report

    Meijer, A. J. M., van den Heuvel-Eibrink, M. M., Brooks, B., Am Zehnhoff-Dinnesen, A. G., Knight, K. R., Freyer, D. R., Chang, K. W., Hero, B., Papadakis, V., Frazier, A. L., Blattmann, C., Windsor, R., Morland, B., Bouffet, E., Rutkowski, S., Tytgat, G. A. M., Geller, J. I., Hunter, L. L., Sung, L., Calaminus, G., Carleton, B. C., Helleman, H. W., Foster, J. H., Kruger, M., Cohn, R. J., Landier, W., van Grotel, M., Brock, P. R., Hoetink, A. E., Rajput, K. M. & Society of Paediatric Oncology Supportive Care Committee, 01.10.2021, In: JAMA ONCOL. 7, 10, p. 1550-1558 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Cauda equina paragangliomas express HOXB13

    Bockmayr, M., Körner, M., Schweizer, L. & Schüller, U., 10.2021, In: NEUROPATH APPL NEURO. 47, 6, p. 889-890 2 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  42. Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes

    Sahoo, S. S., Pastor, V. B., Goodings, C., Voss, R. K., Kozyra, E. J., Szvetnik, A., Noellke, P., Dworzak, M., Starý, J., Locatelli, F., Masetti, R., Schmugge, M., De Moerloose, B., Catala, A., Kállay, K., Turkiewicz, D., Hasle, H., Buechner, J., Jahnukainen, K., Ussowicz, M., Polychronopoulou, S., Smith, O. P., Fabri, O., Barzilai, S., de Haas, V., Baumann, I., Schwarz-Furlan, S., Niewisch, M. R., Sauer, M. G., Burkhardt, B., Lang, P., Bader, P., Beier, R., Müller, I., Albert, M. H., Meisel, R., Schulz, A., Cario, G., Panda, P. K., Wehrle, J., Hirabayashi, S., Derecka, M., Durruthy-Durruthy, R., Göhring, G., Yoshimi-Noellke, A., Ku, M., Lebrecht, D., Erlacher, M., Flotho, C., Strahm, B., Niemeyer, C. M., Wlodarski, M. W. & European Working Group of MDS in Children (EWOG-MDS), 10.2021, In: NAT MED. 27, 10, p. 1806-1817 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Current recommendations for clinical surveillance and genetic testing in rhabdoid tumor predisposition: a report from the SIOPE Host Genome Working Group

    Frühwald, M. C., Nemes, K., Boztug, H., Cornips, M. C. A., Evans, D. G., Farah, R., Glentis, S., Jorgensen, M., Katsibardi, K., Hirsch, S., Jahnukainen, K., Kventsel, I., Kerl, K., Kratz, C. P., Pajtler, K. W., Kordes, U., Ridola, V., Stutz, E. & Bourdeaut, F., 10.2021, In: FAM CANCER. 20, 4, p. 305-316 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Evidence for a low-penetrant extended phenotype of rhabdoid tumor predisposition syndrome type 1 from a kindred with gain of SMARCB1 exon 6

    Kordes, U., Mautner, V-F., Oyen, F., Hagel, C., Hartmann, C., Heuser, M., Frühwald, M., Hasselblatt, M., Oehl-Huber, K., Siebert, R., Schneppenheim, R. & Schüller, U., 10.2021, In: PEDIATR BLOOD CANCER. 68, 10, p. e29185

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  45. Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

    Boer, J. M., Valsecchi, M. G., Hormann, F. M., Antić, Ž., Zaliova, M., Schwab, C., Cazzaniga, G., Arfeuille, C., Cavé, H., Attarbaschi, A., Strehl, S., Escherich, G., Imamura, T., Ohki, K., Grüber, T. A., Sutton, R., Pastorczak, A., Lammens, T., Lambert, F., Li, C. K., Carrillo de Santa Pau, E., Hoffmann, S., Möricke, A., Harrison, C. J., Den Boer, M. L., De Lorenzo, P., Stam, R. W., Bergmann, A. K. & Pieters, R., 10.2021, In: LEUKEMIA. 35, 10, p. 2978-2982 5 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  46. Genetic testing and surveillance in infantile myofibromatosis: a report from the SIOPE Host Genome Working Group

    Hettmer, S., Dachy, G., Seitz, G., Agaimy, A., Duncan, C., Jongmans, M., Hirsch, S., Kventsel, I., Kordes, U., de Krijger, R. R., Metzler, M., Michaeli, O., Nemes, K., Poluha, A., Ripperger, T., Russo, A., Smetsers, S., Sparber-Sauer, M., Stutz, E., Bourdeaut, F., Kratz, C. P. & Demoulin, J-B., 10.2021, In: FAM CANCER. 20, 4, p. 327-336 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients

    Hashem, H., Bucciol, G., Ozen, S., Unal, S., Bozkaya, I. O., Akarsu, N., Taskinen, M., Koskenvuo, M., Saarela, J., Dimitrova, D., Hickstein, D. D., Hsu, A. P., Holland, S. M., Krance, R., Sasa, G., Kumar, A. R., Müller, I., Abreu de Sousa, M., Delafontaine, S., Moens, L., Babor, F., Barzaghi, F., Cicalese, M. P., Bredius, R., van Montfrans, J., Baretta, V., Cesaro, S., Stepensky, P., Benedicte, N., Moshous, D., Le Guenno, G., Boutboul, D., Dalal, J., Brooks, J. P., Dokmeci, E., Dara, J., Lucas, C. L., Hambleton, S., Wilson, K., Jolles, S., Koc, Y., Güngör, T., Schnider, C., Candotti, F., Steinmann, S., Schulz, A., Chambers, C., Hershfield, M., Ombrello, A., Kanakry, J. A. & Meyts, I., 10.2021, In: J CLIN IMMUNOL. 41, 7, p. 1633-1647 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Minimal residual disease, long-term outcome, and IKZF1 deletions in children and adolescents with Down syndrome and acute lymphocytic leukaemia: a matched cohort study

    Michels, N., Boer, J. M., Enshaei, A., Sutton, R., Heyman, M., Ebert, S., Fiocco, M., de Groot-Kruseman, H. A., van der Velden, V. H. J., Barbany, G., Escherich, G., Vora, A., Trahair, T., Dalla-Pozza, L., Pieters, R., Zur Stadt, U., Schmiegelow, K., Moorman, A. V., Zwaan, C. M. & den Boer, M. L., 10.2021, In: LANCET HAEMATOL. 8, 10, p. e700-e710

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. Primary haemophagocytic lymphohistiocytosis (Chédiak-Higashi Syndrome) triggered by acute SARS-CoV-2 infection in a six-week-old infant

    Lange, M., Linden, T., Müller, H. L., Flasskuehler, M. A., Koester, H., Lehmberg, K., Ledig, S., Ehl, S., Heep, A. & Beske, F., 10.2021, In: BRIT J HAEMATOL. 195, 2, p. 198-200 3 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  50. Super-enhancer-based identification of a BATF3/IL-2R-module reveals vulnerabilities in anaplastic large cell lymphoma

    Liang, H-C., Costanza, M., Prutsch, N., Zimmerman, M. W., Gurnhofer, E., Montes-Mojarro, I. A., Abraham, B. J., Prokoph, N., Stoiber, S., Tangermann, S., Lobello, C., Oppelt, J., Anagnostopoulos, I., Hielscher, T., Pervez, S., Klapper, W., Zammarchi, F., Silva, D-A., Garcia, K. C., Baker, D., Janz, M., Schleussner, N., Fend, F., Pospíšilová, Š., Janiková, A., Wallwitz, J., Stoiber, D., Simonitsch-Klupp, I., Cerroni, L., Pileri, S., de Leval, L., Sibon, D., Fataccioli, V., Gaulard, P., Assaf, C., Knörr, F., Damm-Welk, C., Woessmann, W., Turner, S. D., Look, A. T., Mathas, S., Kenner, L. & Merkel, O., 22.09.2021, In: NAT COMMUN. 12, 1, 5577.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma

    DeSisto, J., Lucas Jr, J. T., Xu, K., Donson, A., Lin, T., Sanford, B., Wu, G., Tran, Q. T., Hedges, D., Hsu, C-Y., Armstrong, G. T., Arnold, M., Bhatia, S., Flannery, P., Lemma, R., Hardie, L., Schüller, U., Venkataraman, S., Hoffman, L. M., Dorris, K., Mulcahy Levy, J. M., Hankinson, T. C., Handler, M., Liu, A. K., Foreman, N., Vibhakar, R., Jones, K., Allen, S., Zhang, J., Baker, S. J., Merchant, T. E., Orr, B. A. & Green, A. L., 20.09.2021, In: NAT COMMUN. 12, 1, 5531.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src-family kinases as prognostic markers and potential targets

    Bußmann, L., Hoffer, K., von Bargen, C. M., Droste, C., Lange, T., Kemmling, J., Schröder-Schwarz, J., Vu, A. T., Akingunsade, L., Nollau, P., Rangarajan, S., de Wijn, R., Oetting, A., Müller, C., Böckelmann, L. C., Zech, H. B., Berger, J. C., Möckelmann, N., Busch, C-J., Böttcher, A., Gatzemeier, F., Klinghammer, K., Simnica, D., Binder, M., Struve, N., Rieckmann, T., Schumacher, U., Clauditz, T. S., Betz, C. S., Petersen, C., Rothkamm, K., Münscher, A. & Kriegs, M., 01.09.2021, In: INT J CANCER. 149, 5, p. 1166 - 1180 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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