Department of Stem Cell Transplantation
Publications
- 2011
B-cell receptor epitope recognition correlates with the clinical course of chronic lymphocytic leukemia.
Binder, M., Müller, F., Jackst, A., Lechenne, B., Pantic, M., Bacher, U., Zu Eulenburg, C. G., Veelken, H., Mertelsmann, R., Pasqualini, R., Arap, W. & Trepel, M., 2011, In: CANCER-AM CANCER SOC. 117, 9, p. 1891-1900 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bioequivalence comparison of a new freezing bag (CryoMACS(®)) with the Cryocyte(®) freezing bag for cryogenic storage of human hematopoietic progenitor cells.
Sputtek, A., Lioznov, M., Kröger, N. & Rowe, A. W., 2011, In: CYTOTHERAPY. 13, 4, p. 481-489 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Bone marrow-derived progenitor cells do not contribute to podocyte turnover in the puromycin aminoglycoside and renal ablation models in rats.
Meyer-Schwesinger, C., Lange, C., Bröcker, V., Agustian, P. A., Putri, A. A., Lehmann, U., Raabe, A., Brinkmeyer, M., Kobayashi, E., Schiffer, M., Büsche, G., Kreipe, H. H., Thaiss, F. & Becker, J. U., 2011, In: AM J PATHOL. 178, 2, p. 494-499 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect.
Preuß, E., Muik, A., Riecken, K., Otte, J., von Laer, D. & Fehse, B., 2011, In: J MOL MED. 89, 11, p. 1113-1124 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia.
Atanackovic, D., Luetkens, T., Kloth, B., Fuchs, G., Cao, Y., Hildebrandt, Y., Meyer, S., Bartels, K., Reinhard, H., Lajmi, N., Hegewisch-Becker, S., Schilling, G., Platzbecker, U., Kobbe, G., Schroeder, T., Bokemeyer, C. & Kröger, N., 2011, In: AM J HEMATOL. 86, 11, p. 918-922 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Caspofungin plus posaconazole as salvage therapy of invasive fungal infections in immunocompromised patients.
Lellek, H., Waldenmaier, D., Dahlke, J., Ayuketang Ayuk, F., Wolschke, C., Kröger, N. & Zander, A. R., 2011, In: MYCOSES. 54, 1, p. 39-44 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia.
Haferlach, C., Bacher, U., Kohlmann, A., Schindela, S., Alpermann, T., Kern, W., Schnittger, S. & Haferlach, T., 2011, In: HAEMATOLOGICA. 96, 6, p. 829-836 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Challenges for allogeneic hematopoietic stem cell transplantation in chronic myeloid leukemia in the era of tyrosine kinase inhibitors.
Oyekunle, A., Klyuchnikov, E., Ocheni, S., Kröger, N., Zander, A. R., Baccarani, M. & Bacher, U., 2011, In: ACTA HAEMATOL-BASEL. 126, 1, p. 30-39 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of NPM1-mutated AML with a history of myelodysplastic syndromes or myeloproliferative neoplasms.
Schnittger, S., Bacher, U., Haferlach, C., Alpermann, T., Dicker, F., Sundermann, J., Kern, W. & Haferlach, T., 2011, In: LEUKEMIA. 25, 4, p. 615-621 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating CD34(+) cells as prognostic and follow-up marker in patients with myelofibrosis undergoing allo-SCT.
Alchalby, H., Lioznov, M., Fritzsche-Friedland, U., Badbaran, A., Zabelina, T., Bacher, U., Stübig, T., Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 2011, In: BONE MARROW TRANSPL. 47, 1, p. 143-145 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA.
Schnittger, S., Bacher, U., Haferlach, C., Kern, W., Alpermann, T. & Haferlach, T., 2011, In: HAEMATOLOGICA. 96, 12, p. 1799-1807 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of genetic and clinical aspects in patients with acute myeloid leukemia and myelodysplastic syndromes all with more than 50% of bone marrow erythropoietic cells.
Bacher, U., Haferlach, C., Alpermann, T., Kern, W., Schnittger, S. & Haferlach, T., 2011, In: HAEMATOLOGICA. 96, 9, p. 1284-1292 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Consensus Conference on Clinical Practice in Chronic GVHD: Second-Line Treatment of Chronic Graft-versus-Host Disease.
Wolff, D., Schleuning, M., von Harsdorf, S., Bacher, U., Gerbitz, A., Stadler, M., Ayuketang Ayuk, F., Kiani, A., Schwerdtfeger, R., Vogelsang, G. B., Kobbe, G., Gramatzki, M., Lawitschka, A., Mohty, M., Pavletic, S. Z., Greinix, H. & Holler, E., 2011, In: BIOL BLOOD MARROW TR. 17, 1, p. 1-17 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Control of bone formation by the serpentine receptor Frizzled-9.
Albers, J., Schulze, J., Beil, F. T., Gebauer, M., Baranowsky, A., Keller, J., Marshall, R-P., Wintges, K., Friedrich, F., Priemel, M., Schilling, A., Rueger, J. M., Cornils, K., Fehse, B., Streichert, T., Sauter, G., Jakob, F., Insogna, K. L., Pober, B., Knobeloch, K-P., Francke, U., Amling, M. & Schinke, T., 2011, In: J CELL BIOL. 192, 6, p. 1057-1072 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cytogenetic methods in chronic lymphocytic leukemia.
Haferlach, C. & Bacher, U., 2011, In: Methods Mol Biol. 730, p. 119-130Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Do centrally pre-prepared solutions achieve more reliable drug concentrations than solutions prepared on the ward?
Dehmel, C., Braune, S., Kreymann, K-G., Baehr, M., Langebrake, C., Hilgarth, H., Nierhaus, A., Dartsch, D. C. & Kluge, S., 2011, In: INTENS CARE MED. 37, 8, p. 1311-1316 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Donor KIR haplotype B improves progression-free and overall survival after allogeneic hematopoietic stem cell transplantation for multiple myeloma.
Kröger, N., Zabelina, T., Berger, J., Duske, H., Klyuchnikov, E., Binder, T., Stübig, T., Hildebrandt, Y., Atanackovic, D., Alchalby, H., Ayuketang Ayuk, F., Zander, A. R., Bacher, U. & Eiermann, T., 2011, In: LEUKEMIA. 25, 10, p. 1657-1661 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Drug dosing and monitoring in obese patients undergoing allogenic stem cell transplantation.
Langebrake, C., Bernhardt, F., Baehr, M., Kröger, N. & Zander, A. R., 2011, In: INT J CLIN PHARM-NET. 33, 6, p. 918-924 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Emergence of carbapenemases in Gram-negative bacteria in Hamburg, Germany.
Hentschke, M., Goritzka, V., Belmar Campos, C., Merkel, P., Ilchmann, C., Lellek, H., Scherpe, S., Aepfelbacher, M. & Rohde, H., 2011, In: DIAGN MICR INFEC DIS. 71, 3, p. 312-315 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of CD133 and other putative stem cell markers in uveal melanoma.
Berna-Thill, M., Berna, M., Grierson, R., Reinhart, I., Voelkel, T., Piechaczek, C., Galambos, P., Jager, M. J., Richard, G., Lange, C. & Gehling, U., 2011, In: MELANOMA RES. 21, 5, p. 405-416 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
First-line matched related donor hematopoietic stem cell transplantation compared to immunosuppressive therapy in acquired severe aplastic anemia.
Peinemann, F., Grouven, U., Kröger, N., Bartel, C., Pittler, M. H. & Lange, S., 2011, In: PLOS ONE. 6, 4, p. 18572 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells.
Brassat, U., Balabanov, S., Bali, D., Dierlamm, J., Balabanov, M., Hartmann, U., Sirma, H., Günes, C., Wege, H., Fehse, B., Gontarewicz, A., Dikomey, E., Borgmann, K. & Brümmendorf, T., 2011, In: EXP HEMATOL. 39, 1, p. 62-66 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ganglioneuroblastoma infiltrating the bone marrow in an adult.
Bacher, U., Christopeit, M., Wiedemann, B., Leuschner, I., Haferlach, T. & Choschzick, M., 2011, In: BRIT J HAEMATOL. 153, 5, p. 544 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gene therapy strategies: can we eradicate HIV?
van Lunzen, J., Fehse, B. & Hauber, J., 2011, In: CURR HIV-AIDS REP. 8, 2, p. 78-84 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic Modifications – Possibilities and Limits of Gene Therapy
Fehse, B., 2011, Human Nature and Self Design. mentis Verlag Paderborn, p. 113-136 24 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Gentherapie in Deutschland. Eine Einführung
Domasch, S. & Fehse, B., 2011, Gentherapie in Deutschland: Eine interdisziplinäre Bestandsaufnahme. Themenband des Gentechnologieberichts. Forum W - Wissenschaftlicher Verlag, p. 31-40 10 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
High-dose chemotherapy followed by autologous stem cell transplantation for metastatic rhabdomyosarcoma--a systematic review.
Peinemann, F., Kröger, N., Bartel, C., Grouven, U., Pittler, M., Erttmann, R. & Kulig, M., 2011, In: PLOS ONE. 6, 2, p. 17127 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation.
Cavo, M., Rajkumar, S. V., Palumbo, A., Moreau, P., Orlowski, R., Bladé, J., Sezer, O., Ludwig, H., Dimopoulos, M. A., Attal, M., Sonneveld, P., Boccadoro, M., Anderson, K. C., Richardson, P. G., Bensinger, W., Johnsen, H. E., Kröger, N., Gahrton, G., Bergsagel, P. L., Vesole, D. H., Einsele, H., Jagannath, S., Niesvizky, R., Durie, B. G. M., Jesus, S. M., Lonial, S. & Group, I. M. W., 2011, In: BLOOD. 117, 23, p. 6063-6073 23.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Minimal residual disease diagnostics and chimerism in the post-transplant period in acute myeloid leukemia.
Bacher, U., Haferlach, T., Fehse, B., Schnittger, S. & Kröger, N., 2011, In: SCI WORLD J. 11, p. 310-319Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Minimal residual disease following allogeneic hematopoietic stem cell transplantation.
Kröger, N., Miyamura, K. & Bishop, M. R., 2011, In: BIOL BLOOD MARROW TR. 17, 1, p. 94-100 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular diagnostics, targeted therapy, and the indication for allogeneic stem cell transplantation in acute lymphoblastic leukemia.
Oyekunle, A., Haferlach, T., Kröger, N., Klyuchnikov, E., Zander, A. R., Schnittger, S. & Bacher, U., 2011, In: Adv Hematol. 2011, p. 154745Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Myogenic differentiation of mesenchymal stem cells co-cultured with primary myoblasts.
Beier, J. P., Bitto, F. F., Lange, C., Klumpp, D., Arkudas, A., Bleiziffer, O., Boos, A. M., Horch, R. E. & Kneser, U., 2011, In: CELL BIOL INT. 35, 4, p. 397-406 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
National Cancer Institute's First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: summary and recommendations from the organizing committee.
Bishop, M. R., Alyea, E. P., Cairo, M. S., Falkenburg, J. H. F., June, C. H., Kröger, N., Little, R. F., Miller, J. S., Pavletic, S. Z., Porter, D. L., Riddell, S. R., van Besien, K., Wayne, A. S., Weisdorf, D. J., Wu, R. S. & Giralt, S., 2011, In: BIOL BLOOD MARROW TR. 17, 4, p. 443-454 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Patients with multiple myeloma develop SOX2-specific autoantibodies after allogeneic stem cell transplantation.
Kobold, S., Tams, S., Luetkens, T., Cao, Y., Sezer, O., Bartels, B. M., Reinhard, H., Templin, J., Bartels, K., Hildebrandt, Y., Lajmi, N., Marx, A., Haag, F., Bokemeyer, C., Kröger, N. & Atanackovic, D., 2011, In: Clin Dev Immunol. 2011, p. 302145Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Perspektivische Entwicklungen in der Stammzelltransplantation: Zelltherapie.
Fehse, B. & Lange, C., 2011, Allogene Stammzelltherapie – Grundlagen, Indikationen und Perspektiven.. Kröger, N. & Zander, A. R. (eds.). 1.-3. ed. Bremen: Uni-Med, p. 134-142 (Allogene Stammzelltherapie – Grundlagen, Indikationen und Perspektiven.).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet.
Barbui, T., Barosi, G., Birgegard, G., Cervantes, F., Finazzi, G., Griesshammer, M., Harrison, C., Hasselbalch, H. C., Hehlmann, R., Hoffman, R., Kiladjian, J-J., Kröger, N., Mesa, R., McMullin, M. F., Pardanani, A., Passamonti, F., Vannucchi, A. M., Reiter, A., Silver, R. T., Verstovsek, S., Tefferi, A. & LeukemiaNet, E., 2011, In: J CLIN ONCOL. 29, 6, p. 761-770 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Plerixafor with and without chemotherapy in poor mobilizers: results from the German compassionate use program.
Hübel, K., Fresen, M. M., Salwender, H., Basara, N., Beier, R., Theurich, S., Christopeit, M., Bogner, C., Galm, O., Hartwig, R., Heits, F., Lordick, F., Rösler, W., Wehler, D., Zander, A. R., Albert, M. H., Dressler, S., Ebinger, M., Frickhofen, N., Hertenstein, B., Kiehl, M., Liebler, S., von Lilienfeld-Toal, M., Weidmann, E., Weigelt, C., Lange, F. & Kröger, N., 2011, In: BONE MARROW TRANSPL. 46, 8, p. 1045-1052 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prognosis in patients with MDS or AML and bone marrow blasts between 10% and 30% is not associated with blast counts but depends on cytogenetic and molecular genetic characteristics.
Bacher, U., Kern, W., Alpermann, T., Schnittger, S., Kohlmann, A., Klein, H-U., Dugas, M., Haferlach, C. & Haferlach, T., 2011, In: LEUKEMIA. 25, 8, p. 1361-1364 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prognostic impact of FLT3-ITD load in NPM1 mutated acute myeloid leukemia.
Schnittger, S., Bacher, U., Kern, W., Alpermann, T., Haferlach, C. & Haferlach, T., 2011, In: LEUKEMIA. 25, 8, p. 1297-1304 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Radiation rescue: mesenchymal stromal cells protect from lethal irradiation.
Lange, C., Brunswig-Spickenheier, B., Capallo-Obermann, H., Eggert, K., Gehling, U., Rudolph, C., Schlegelberger, B., Cornils, K., Zustin, J., Spiess, A-N. & Zander, A. R., 2011, In: PLOS ONE. 6, 1, p. 14486 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Recent advances in diagnosis, molecular pathology and therapy of chronic myelomonocytic leukaemia.
Bacher, U., Haferlach, T., Schnittger, S., Kreipe, H. & Kröger, N., 2011, In: BRIT J HAEMATOL. 153, 2, p. 149-167 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Retroviral insertional mutagenesis can contribute to immortalization of mature T lymphocytes.
Newrzela, S., Cornils, K., Heinrich, T., Schläger, J., Yi, J-H., Lysenko, O., Kimpel, J., Fehse, B. & Dorothee, V. L., 2011, In: MOL MED. 17, 11-12, p. 1223-1232 11-12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RGB marking facilitates multicolor clonal cell tracking.
Riecken, K., Thomaschewski, M., Warlich, M., Volz, T., Cornils, K., Niebuhr, B., Täger, M., Lütgehetmann, M., Pollok, J-M., Stocking, C., Dandri-Petersen, M., Benten, D. & Fehse, B., 2011, In: NAT MED. 17, 4, p. 504-509 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Several lymphoma-specific genetic events in parallel can be found in mature B-cell neoplasms.
Bacher, U., Haferlach, T., Alpermann, T., Kern, W., Schnittger, S. & Haferlach, C., 2011, In: GENE CHROMOSOME CANC. 50, 1, p. 43-50 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stand wissenschaftlicher und medizinischer Entwicklungen
Fehse, B., Baum, C., Schmidt, M. & Kalle, C., 2011, Gentherapie in Deutschland: Eine interdisziplinäre Bestandsaufnahme. Themenband des Gentechnologieberichts. Forum W - Wissenschaftlicher Verlag, p. 41-126 86 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Subclones with the t(9;22)/BCR-ABL1 rearrangement occur in AML and seem to cooperate with distinct genetic alterations.
Bacher, U., Haferlach, T., Alpermann, T., Zenger, M., Hochhaus, A., Beelen, D. W., Uppenkamp, M., Rummel, M., Kern, W., Schnittger, S. & Haferlach, C., 2011, In: BRIT J HAEMATOL. 152, 6, p. 713-720 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Surface molecule CD229 as a novel target for the diagnosis and treatment of multiple myeloma.
Atanackovic, D., Panse, J., Hildebrandt, Y., Jadczak, A., Kobold, S., Cao, Y., Templin, J., Meyer, S., Reinhard, H., Bartels, K., Lajmi, N., Zander, A. R., Marx, A., Bokemeyer, C. & Kröger, N., 2011, In: HAEMATOLOGICA. 96, 10, p. 1512-1520 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Role of Allogeneic Stem Cell Transplantation in Relapsed/Refractory Hodgkin's Lymphoma Patients.
Klyuchnikov, E., Bacher, U., Kröger, N., Kazantsev, I., Zabelina, T., Ayuketang Ayuk, F. & Zander, A. R., 2011, In: ANN HEMATOL. 2011, p. 974658Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Thrombospondin-1 (TSP-1) in primary myelofibrosis (PMF) - a megakaryocyte-derived biomarker which largely discriminates PMF from essential thrombocythemia.
Muth, M., Engelhardt, B. M., Kröger, N., Hussein, K., Schlué, J., Büsche, G., Kreipe, H. H. & Bock, O., 2011, In: ANN HEMATOL. 90, 1, p. 33-40 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Unrelated cord blood transplantation in adults with myelodysplasia or secondary acute myeloblastic leukemia: a survey on behalf of Eurocord and CLWP of EBMT.
Robin, M., Sanz, G. F., Ionescu, I., Rio, B., Sirvent, A., Renaud, M., Carreras, E., Milpied, N., Mohty, M., Beguin, Y., Bordigoni, P., de Witte, T., Picardi, A., Purtill, D., Gluckman, E., Kröger, N. & Rocha, V., 2011, In: LEUKEMIA. 25, 1, p. 75-81 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review