Department of Stem Cell Transplantation

Publications

  1. 2012
  2. Development and validation of a real-time quantification assay to detect and monitor BRAFV600E mutations in hairy cell leukemia.

    Schnittger, S., Bacher, U., Haferlach, T., Wendland, N., Ulke, M., Dicker, F., Grossmann, V., Haferlach, C. & Kern, W., 2012, In: BLOOD. 119, 13, p. 3151-3154 13.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Diagnostic performance of whole-body MRI for the detection of persistent or relapsing disease in multiple myeloma after stem cell transplantation.

    Bannas, P., Hentschel, H. B., Bley, T., Treszl, A., Zu Eulenburg, C. G., Derlin, T., Yamamura, J., Adam, G., Stübig, T., Kröger, N. & Weber, C., 2012, In: EUR RADIOL. 22, 9, p. 2007-2012 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. [Diagnostics of acute leukemias: interaction of phenotypic and genetic methods].

    Bacher, U., Haferlach, C., Schnittger, S., Kern, W., Ott, M. M. & Haferlach, T., 2012, In: PATHOLOGE. 33, 6, p. 528-538 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Discovered on gastrointestinal stromal tumour 1 (DOG1): a useful immunohistochemical marker for diagnosing chondroblastoma.

    Akpalo, H., Lange, C. & Zustin, J., 2012, In: HISTOPATHOLOGY. 60, 7, p. 1099-1106 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Diversity of the juxtamembrane and TKD1 mutations (exons 13-15) in the FLT3 gene with regards to mutant load, sequence, length, localization, and correlation with biological data.

    Schnittger, S., Bacher, U., Haferlach, C., Alpermann, T., Kern, W. & Haferlach, T., 2012, In: GENE CHROMOSOME CANC. 51, 10, p. 910-924 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Donor lymphocyte infusions and second transplantation as salvage treatment for relapsed myelofibrosis after reduced-intensity allografting.

    Klyuchnikov, E., Holler, E., Bornhäuser, M., Kobbe, G., Nagler, A., Shimoni, A., Könecke, C., Wolschke, C., Bacher, U., Zander, A. R. & Kröger, N., 2012, In: BRIT J HAEMATOL. 159, 2, p. 172-181 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Efficient lentiviral transduction and transgene expression in primary human B cells.

    Mock, U., Thiele, R., Uhde, A., Fehse, B. & Horn, S., 2012, In: HUM GENE THER METHOD. 23, 6, p. 408-415 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. ETV6 rearrangements are recurrent in myeloid malignancies and are frequently associated with other genetic events.

    Haferlach, C., Bacher, U., Schnittger, S., Alpermann, T., Zenger, M., Kern, W. & Haferlach, T., 2012, In: GENE CHROMOSOME CANC. 51, 4, p. 328-337 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. European data on stem cell mobilization with plerixafor in non-Hodgkin's lymphoma, Hodgkin's lymphoma and multiple myeloma patients. A subgroup analysis of the European Consortium of stem cell mobilization.

    Hübel, K., Fresen, M. M., Apperley, J. F., Basak, G. W., Douglas, K. W., Gabriel, I. H., Geraldes, C., Jaksic, O., Koristek, Z., Kröger, N., Lanza, F., Lemoli, R. M., Mikala, G., Selleslag, D., Worel, N., Mohty, M. & Duarte, R. F., 2012, In: BONE MARROW TRANSPL. 47, 8, p. 1046-1050 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Expression of CEBPA is reduced in RUNX1-mutated acute myeloid leukemia.

    Grossmann, V., Bacher, U., Kohlmann, A., Butschalowski, K., Roller, A., Jeromin, S., Dicker, F., Kern, W., Schnittger, S., Haferlach, T. & Haferlach, C., 2012, In: BLOOD CANCER J. 2, p. 86

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.

    Preukschas, M., Hagel, C., Schulte, A., Riecken, K., Lamszus, K., Sievert, H., Pällmann, N., Bokemeyer, C., Hauber, J., Balabanov, M. & Balabanov, S., 2012, In: PLOS ONE. 7, 8, p. 43468 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. EZH2 mutations and their association with PICALM-MLLT10 positive acute leukaemia.

    Grossmann, V., Bacher, U., Kohlmann, A., Artusi, V., Klein, H-U., Dugas, M., Schnittger, S., Alpermann, T., Kern, W., Haferlach, T. & Haferlach, C., 2012, In: BRIT J HAEMATOL. 157, 3, p. 387-390 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Frequency and prognostic impact of the aberrant CD8 expression in 5,523 patients with chronic lymphocytic leukemia.

    Kern, W., Bacher, U., Haferlach, C., Alpermann, T., Dicker, F., Schnittger, S. & Haferlach, T., 2012, In: CYTOM PART B-CLIN CY. 82, 3, p. 145-150 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Identification of genetic parameters associated with disease progression in plasma cell myeloma.

    Bacher, U. & Binder, M., 2012, In: LEUKEMIA RES. 36, 1, p. 23-24 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Immunotherapy for multiple myeloma.

    Kröger, N., Mohty, M., Nagler, A. & Yi, Q., 2012, In: Clin Dev Immunol. 2012, p. 797165

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Impact of the NK cell receptor LIR-1 (ILT-2/CD85j/LILRB1) on cytotoxicity against multiple myeloma.

    Heidenreich, S., Zu Eulenburg, C. G., Hildebrandt, Y., Stübig, T., Sierich, H., Badbaran, A., Eiermann, T., Binder, T. & Kröger, N., 2012, In: Clin Dev Immunol. 2012, p. 652130

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Longitudinal analysis of tetanus- and influenza-specific IgG antibodies in myeloma patients.

    Kobold, S., Luetkens, T., Bartels, B. M., Cao, Y., Hildebrandt, Y., Sezer, O., Reinhard, H., Templin, J., Bartels, K., Lajmi, N., Haag, F., Bokemeyer, C., Kröger, N. & Atanackovic, D., 2012, In: Clin Dev Immunol. 2012, p. 134081

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Molecular analyses of 15,542 patients with suspected BCR-ABL1-negative myeloproliferative disorders allow to develop a stepwise diagnostic workflow.

    Schnittger, S., Bacher, U., Eder, C., Dicker, F., Alpermann, T., Grossmann, V., Kohlmann, A., Kern, W., Haferlach, C. & Haferlach, T., 2012, In: HAEMATOLOGICA. 97, 10, p. 1582-1585 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Molecular analysis of RAS-RAF tyrosine-kinase signaling pathway alterations in patients with plasma cell myeloma.

    Grossmann, V., Bacher, U., Artusi, V., Kohlmann, A., Nadarajah, N., Kern, W., Schnittger, S., Haferlach, T. & Haferlach, C., 2012, In: BLOOD CANCER J. 2, p. 85

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Monitoring and prevention of relapse after allogeneic hematopoietic cell transplantation for myeloid malignancies.

    Bacher, U., Talano, J-A. & Bishop, M. R., 2012, In: BIOL BLOOD MARROW TR. 18, 1 Suppl, p. 62-73 1 Suppl.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Monoclonal B-cell lymphocytosis is closely related to chronic lymphocytic leukaemia and may be better classified as early-stage CLL.

    Kern, W., Bacher, U., Haferlach, C., Dicker, F., Alpermann, T., Schnittger, S. & Haferlach, T., 2012, In: BRIT J HAEMATOL. 157, 1, p. 86-96 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Multilineage dysplasia does not influence prognosis in CEBPA-mutated AML, supporting the WHO proposal to classify these patients as a unique entity.

    Bacher, U., Schnittger, S., Macijewski, K., Grossmann, V., Kohlmann, A., Alpermann, T., Kowarsch, A., Nadarajah, N., Kern, W., Haferlach, C. & Haferlach, T., 2012, In: BLOOD. 119, 20, p. 4719-4722 20.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation: diagnostic and therapeutic challenges.

    Shah, N. N., Bacher, U., Fry, T., Calvo, K. R., Stetler-Stevenson, M., Arthur, D. C., Kurlander, R., Baird, K., Wise, B., Giralt, S., Bishop, M., Hardy, N. M. & Wayne, A. S., 2012, In: AM J HEMATOL. 87, 9, p. 916-922 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts.

    Schulze, J., Riecken, K., Baranowsky, A., Streichert, T., Lange, T., Spiro, A. S., Albers, J., Seitz, S., Zustin, J., Amling, M., Fehse, B. & Schinke, T., 2012, In: CANCER LETT. 317, 1, p. 106-113 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Platelet lysate suppresses the expression of lipocalin-type prostaglandin D2 synthase that positively controls adipogenic differentiation of human mesenchymal stromal cells.

    Lange, C., Brunswig-Spickenheier, B., Eissing, L. & Scheja, L., 2012, In: EXP CELL RES. 318, 18, p. 2284-2296 18.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Plerixafor for autologous peripheral blood stem cell mobilization in patients previously treated with fludarabine or lenalidomide.

    Malard, F., Kröger, N., Gabriel, I. H., Hübel, K., Apperley, J. F., Basak, G. W., Douglas, K. W., Geraldes, C., Jaksic, O., Koristek, Z., Lanza, F., Lemoli, R., Mikala, G., Selleslag, D., Worel, N., Mohty, M. & Duarte, R. F., 2012, In: BIOL BLOOD MARROW TR. 18, 2, p. 314-317 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Prognoses of MDS subtypes RARS, RCMD and RCMD-RS are comparable but cytogenetics separates a subgroup with inferior clinical course.

    Bacher, U., Kern, W., Alpermann, T., Schnittger, S., Haferlach, C. & Haferlach, T., 2012, In: LEUKEMIA RES. 36, 7, p. 826-831 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Replacement of hematopoietic system by allogeneic stem cell transplantation in myelofibrosis patients induces rapid regression of bone marrow fibrosis.

    Kröger, N., Kvasnicka, M. & Thiele, J., 2012, In: Fibrogenesis Tissue Repair. 5 Suppl 1, p. 25

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. RGB marking : Vielfarbige Zellmarkierung zur klonalen Analyse

    Riecken, K., Thomaschewski, M., Warlich, M., Cornils, K., Benten, D. & Fehse, B., 2012, In: Laborwelt. 13, 1, p. 7-9 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. RGB marking with lentiviral vectors for multicolor clonal cell tracking.

    Riecken, K., Thomaschewski, M., Benten, D. & Fehse, B., 2012, In: NAT PHYS. 7, 5, p. 839-849 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Risk models predicting survival after reduced-intensity transplantation for myelofibrosis.

    Alchalby, H., Yunus, D-R., Zabelina, T., Kobbe, G., Holler, E., Bornhäuser, M., Schwerdtfeger, R., Bethge, W., Kvasnicka, H. M., Büsche, G., Ayuketang Ayuk, F., Bacher, U., Zander, A. R. & Kröger, N., 2012, In: BRIT J HAEMATOL. 157, 1, p. 75-85 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Role of interleukin 16 in multiple myeloma.

    Atanackovic, D., Hildebrandt, Y., Templin, J., Cao, Y., Keller, C., Panse, J., Meyer, S., Reinhard, H., Bartels, K., Lajmi, N., Sezer, O., Zander, A. R., Marx, A., Uhlig, R., Zustin, J., Bokemeyer, C. & Kröger, N., 2012, In: JNCI-J NATL CANCER I. 104, 13, p. 1005-1020 13.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Screening of Potential HIV-1 Inhibitors/Replication Blockers Using Secure Lentiviral in Vitro System.

    Prokofjeva, M. M., Spirin, P. V., Yanvarev, D. V., Ivanov, A. V., Novikov, M. S., Stepanov, O. A., Gottikh, M. B., Kochetkov, S. N., Fehse, B., Stocking, C. & Prassolov, V. S., 2012, In: ACTA NATURAE. 3, 4, p. 55-65 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Similar incidences of TP53 deletions in extramedullary organ infiltrations, soft tissue and osteolyses of patients with multiple myeloma.

    Billecke, L., Murga-Penas, E-M., May, A. M., Engelhardt, M., Nagler, A., Leiba, M., Schiby, G., Kröger, N., Zustin, J., Marx, A., Matschke, J., Tiemann, M., Goekkurt, E., Bokemeyer, C. & Schilling, G., 2012, In: ANTICANCER RES. 32, 5, p. 2031-2034 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. SOCS3 promotes interleukin-17 expression of human T cells.

    Kleinsteuber, K., Heesch, K., Schattling, S., Sander-Juelch, C., Mock, U., Riecken, K., Fehse, B., Fleischer, B. & Jacobsen, M., 2012, In: BLOOD. 120, 22, p. 4374-4382 22.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. TET2 deletions are a recurrent but rare phenomenon in myeloid malignancies and are frequently accompanied by TET2 mutations on the remaining allele.

    Bacher, U., Weissmann, S., Kohlmann, A., Schindela, S., Alpermann, T., Schnittger, S., Kern, W., Haferlach, T. & Haferlach, C., 2012, In: BRIT J HAEMATOL. 156, 1, p. 67-75 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. The benefit of population-based studies for older patients with acute myeloid leukemia.

    Bacher, U. & Haferlach, T., 2012, In: HAEMATOLOGICA. 97, 12, p. 1781-1782 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Therapy-related myeloid neoplasms following treatment with radioiodine.

    Schroeder, T., Kuendgen, A., Kayser, S., Kröger, N., Braulke, F., Platzbecker, U., Klärner, V., Zohren, F., Haase, D., Stadler, M., Schlenk, R., Czibere, A. G., Bruns, I., Fenk, R., Gattermann, N., Haas, R., Kobbe, G. & Germing, U., 2012, In: HAEMATOLOGICA. 97, 2, p. 206-212 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. The role of regulatory T cells and TH17 cells in multiple myeloma.

    Braga, W. M. T., Atanackovic, D. & Colleoni, G. W. B., 2012, In: Clin Dev Immunol. 2012, p. 293479

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Three novel cytogenetically cryptic EVI1 rearrangements associated with increased EVI1 expression and poor prognosis identified in 27 acute myeloid leukemia cases.

    Haferlach, C., Bacher, U., Grossmann, V., Schindela, S., Zenger, M., Kohlmann, A., Kern, W., Haferlach, T. & Schnittger, S., 2012, In: GENE CHROMOSOME CANC. 51, 12, p. 1079-1085 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Treatment of Ischemia/Reperfusion Injury of the Kidney with Mesenchymal Stromal Cells

    Lange, C., Zander, A. R. & Westenfelder, C., 2012, Stem Cells and Cancer Stem Cells,Volume 3. Springer Berlin Heidelberg, p. 241-250 10 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  43. Treatment, risk factors, and outcome of adults with relapsed AML after reduced intensity conditioning for allogeneic stem cell transplantation.

    Schmid, C., Labopin, M., Nagler, A., Niederwieser, D., Castagna, L., Tabrizi, R., Stadler, M., Kuball, J., Cornelissen, J., Vorlicek, J., Socié, G., Falda, M., Vindeløv, L., Ljungman, P., Jackson, G., Kröger, N., Rank, A., Polge, E., Rocha, V., Mohty, M., Blood, A. L. W. P. O. T. E. G. F. & Transplantation, M., 2012, In: BLOOD. 119, 6, p. 1599-1606 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases.

    Schnittger, S., Bacher, U., Alpermann, T., Reiter, A., Ulke, M., Dicker, F., Eder, C., Kohlmann, A., Grossmann, V., Kowarsch, A., Kern, W., Haferlach, C. & Haferlach, T., 2012, In: HAEMATOLOGICA. 97, 12, p. 1890-1894 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. 2011
  46. Purification of CD4+ T cells for adoptive immunotherapy after allogeneic hematopoietic stem cell transplantation

    Klyuchnikov, E., Sputtek, A., Slesarchuk, O., Lioznov, M., Stübig, T., Bacher, U., Amtsfeld, G., Merle, E., Reckhaus, M-L., Fehse, B., Wolschke, C., Adjalle, R., Ayuketang Ayuk, F., Zander, A. R. & Kröger, N., 01.03.2011, In: BIOL BLOOD MARROW TR. 17, 3, p. 374-383 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells

    Michaelis, M., Rothweiler, F., Barth, S., Cinatl, J., van Rikxoort, M., Löschmann, N., Voges, Y., Breitling, R., von Deimling, A., Rödel, F., Riecken, K., Fehse, B., Mack, E., Stiewe, T., Doerr, H. W., Speidel, D., Cinatl, J. & Riecken, K., 01.01.2011, In: CELL DEATH DIS. 2, p. e243

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. A copy number repeat polymorphism in the transactivation domain of the CEPBA gene is possibly associated with a protective effect against acquired CEBPA mutations: an analysis in 1135 patients with AML and 187 healthy controls.

    Schnittger, S., Bacher, U., Eder, C., Lohse, P., Haferlach, C., Kern, W. & Haferlach, T., 2011, In: EXP HEMATOL. 39, 1, p. 87-94 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Acute monoblastic/monocytic leukemia and chronic myelomonocytic leukemia share common immunophenotypic features but differ in the extent of aberrantly expressed antigens and amount of granulocytic cells.

    Kern, W., Bacher, U., Haferlach, C., Schnittger, S. & Haferlach, T., 2011, In: LEUKEMIA LYMPHOMA. 52, 1, p. 92-100 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Allogeneic stem cell transplantation for myelodysplastic syndromes with bone marrow fibrosis.

    Kröger, N., Zabelina, T., van Biezen, A., Brand, R., Niederwieser, D., Martino, R., Lim, Z. Y., Onida, F., Schmid, C., Garderet, L., Robin, M., van Gelder, M., Marks, R., Symeonidis, A., Kobbe, G. & de Witte, T., 2011, In: HAEMATOLOGICA. 96, 2, p. 291-297 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Approaches to relapse after allogeneic stem cell transplantation.

    Kröger, N., 2011, In: CURR OPIN ONCOL. 23, 2, p. 203-208 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Assessment of physiologic natural killer cell cytotoxicity in vitro.

    Duske, H., Sputtek, A., Binder, T., Kröger, N., Schrepfer, S. & Eiermann, T., 2011, In: HUM IMMUNOL. 72, 11, p. 1007-1012 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review