Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA.

Susanne Schnittger; Ulrike Bacher; Claudia Haferlach; Wolfgang Kern; Tamara Alpermann; Torsten Haferlach

doi:10.3324/haematol.2011.049007

Clinical impact of FLT3 mutation load in acute promyelocytic leukemia with t(15;17)/PML-RARA.

Susanne Schnittger
Ulrike Bacher
Claudia Haferlach
Wolfgang Kern
Tamara Alpermann
Torsten Haferlach

Related Research units

Department of Stem Cell Transplantation

Abstract

Combined treatment with all-trans-retinoic acid and chemotherapy is extremely efficient in patients with acute promyelocytic leukemia with t(15;17)/PML-RARA, but up to 15% of patients relapse.

Bibliographical data

Original language	English
Article number	12
ISSN	0390-6078
DOIs	https://doi.org/10.3324/haematol.2011.049007
Publication status	Published - 2011

pubmed	21859732