Department of Biochemistry and Molecular Cell Biology

Publications

  1. Fat Quantification in Dual-Layer Detector Spectral Computed Tomography: Experimental Development and First In-Patient Validation

    Molwitz, I., Campbell, G. M., Yamamura, J., Knopp, T., Toedter, K., Fischer, R., Wang, Z. J., Busch, A., Ozga, A-K., Zhang, S., Lindner, T., Sevecke, F., Grosser, M., Adam, G. & Szwargulski, P., 01.07.2022, In: INVEST RADIOL. 57, 7, p. 463-469 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  2. Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use

    Worthmann, A., Ridder, J., Piel, S. Y. L., Evangelakos, I., Musfeldt, M., Voß, H., O'Farrell, M., Fischer, A. W., Adak, S., Sundd, M., Siffeti, H., Haumann, F., Kloth, K., Bierhals, T., Heine, M., Pertzborn, P., Pauly, M., Scholz, J-J., Kundu, S., Fuh, M. M., Neu, A., Tödter, K., Hempel, M., Knippschild, U., Semenkovich, C. F., Schlüter, H., Heeren, J., Scheja, L., Kubisch, C. & Schlein, C., 02.01.2024, In: NAT COMMUN. 15, 1, p. 45

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues

    Schlein, C., Talukdar, S., Heine, M., Fischer, A. W., Krott, L. M., Nilsson, S. K., Brenner, M. B., Heeren, J. & Scheja, L., 08.03.2016, In: CELL METAB. 23, 3, p. 441-53 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Final-year medical students' self-assessment of facets of competence for beginning residents

    Bußenius, L., Harendza, S., van den Bussche, H. & Selch, S., 07.02.2022, In: BMC MED EDUC. 22, 1, 82.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. FoxO transcription factors are required for hepatic HDL-cholesterol clearance

    Lee, S. X., Heine, M., Schlein, C., Ramakrishnan, R., Liu, J., Belnavis, G., Haimi, I., Fischer, A. W., Ginsberg, H., Heeren, J., Rinninger, F. & Haeusler, R. A., 02.04.2018, In: J CLIN INVEST. 128, 4, p. 1615-1626 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Fragebogenbasierte Anforderungsanalyse für das Berufsbild des Anästhesiologen

    Gassner, S., Oubaid, V., Hampe, W., Zöllner, C. & Kubitz, J. C., 2018, In: ANASTH INTENSIVMED. 59, p. 114-120

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus.

    Musunuru, K., Strong, A., Frank-Kamenetsky, M., Lee, N. E., Ahfeldt, T., Sachs, K. V., Li, X., Li, H., Kuperwasser, N., Ruda, V. M., Pirruccello, J. P., Muchmore, B., Prokunina-Olsson, L., Hall, J. L., Schadt, E. E., Morales, C. R., Lund-Katz, S., Phillips, M. C., Wong, J., Cantley, W., Racie, T., Ejebe, K. G., Orho-Melander, M., Melander, O., Koteliansky, V., Fitzgerald, K., Krauss, R. M., Cowan, C. A., Kathiresan, S. & Rader, D. J., 2010, In: NATURE. 466, 7307, p. 714-719 7307.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Frontrunners of T cell activation: Initial, localized Ca2+ signals mediated by NAADP and the type 1 ryanodine receptor

    Wolf, I. M. A., Diercks, B-P., Gattkowski, E., Czarniak, F., Kempski, J., Werner, R., Schetelig, D., Mittrücker, H-W., Schumacher, V., von Osten, M., Lodygin, D., Flügel, A., Fliegert, R. & Guse, A. H., 13.10.2015, In: SCI SIGNAL. 8, 398, p. Art. ra102 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Full focus on calcium

    Parys, J. B. & Guse, A. H., 17.09.2019, In: SCIENCE SIGNALING. 12, 599

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Functional ryanodine receptor expression is required for NAADP-mediated local Ca2+ signaling in T-lymphocytes

    Dammermann, W. & Guse, A. H., 03.06.2005, In: J BIOL CHEM. 280, 22, p. 21394-9 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Function of the neuropeptide head activator for early neural and neuroendocrine development.

    Hampe, W., Hermans-Borgmeyer, I. & Schaller, H. C., 1999, In: Results Probl Cell Differ. 26, p. 323-337

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Gadospin f-enhanced magnetic resonance imaging for diagnosis and monitoring of atherosclerosis: validation with transmission electron microscopy and x-ray fluorescence imaging in the apolipoprotein e-deficient mouse

    Jung, C., Dučić, T., Reimer, R., Koziolek, E., Kording, F., Heine, M., Adam, G., Ittrich, H. & Kaul, M. G., 2014, In: MOL IMAGING. 13, p. 1-10 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. General population’s knowledge about the anatomical locations of organs and medical terms today and 50 years ago: a replication study

    Harendza, S., Münter, A., Bußenius, L. & Bittner, A., 22.07.2021, In: GMS Journal for Medical Education. 38, 5, p. Doc94 Doc94.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Generation and characterization of antagonistic anti-human CD39 nanobodies

    Menzel, S., Duan, Y., Hambach, J., Albrecht, B., Wendt-Cousin, D., Winzer, R., Tolosa, E., Rissiek, A., Guse, A. H., Haag, F., Magnus, T., Koch-Nolte, F. & Rissiek, B., 2024, In: FRONT IMMUNOL. 15, p. 1328306

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Genetic Dissection of Tissue-Specific Apolipoprotein E Function for Hypercholesterolemia and Diet-Induced Obesity

    Wagner, T., Bartelt, A., Schlein, C. & Heeren, J., 2015, In: PLOS ONE. 10, 12, e0145102.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease.

    Linsel-Nitschke, P., Heeren, J., Aherrahrou, Z., Bruse, P., Gieger, C., Illig, T., Prokisch, H., Heim, K., Doering, A., Peters, A., Meitinger, T., Wichmann, H-E., Hinney, A., Reinehr, T., Roth, C., Ortlepp, J. R., Soufi, M., Sattler, A. M., Schaefer, J., Stark, K., Hengstenberg, C., Schaefer, A., Schreiber, S., Kronenberg, F., Samani, N. J., Schunkert, H. & Erdmann, J., 2010, In: ATHEROSCLEROSIS. 208, 1, p. 183-189 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification

    Maire, C. L., Fuh, M. M., Kaulich, K., Fita, K. D., Stevic, I., Heiland, D. H., Welsh, J. A., Jones, J. C., Görgens, A., Ricklefs, T., Dührsen, L., Sauvigny, T., Joosse, S. A., Reifenberger, G., Pantel, K., Glatzel, M., Miklosi, A. G., Felce, J. H., Caselli, M., Pereno, V., Reimer, R., Schlüter, H., Westphal, M., Schüller, U., Lamszus, K. & Ricklefs, F. L., 01.07.2021, In: NEURO-ONCOLOGY. 23, 7, p. 1087-1099 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. German Physicians and Medical Students Do Not Represent the Population They Serve

    Groene, O., Huelmann, T., Hampe, W. & Emami, P., 06.06.2023, In: HEALTHCARE-BASEL. 11, 12, 1662.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Glucocorticoid-Induced Obesity Develops Independently of UCP1

    Luijten, I. H. N., Brooks, K., Boulet, N., Shabalina, I. G., Jaiprakash, A., Carlsson, B., Fischer, A. W., Cannon, B. & Nedergaard, J., 07.05.2019, In: CELL REP. 27, 6, p. 1686-1698.e5

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. GMA-Jahrestagung 2014 in Hamburg - Ankündigung

    Hampe, W. & Kuhnigk, O., 15.05.2014, In: GMS Z Med Ausbild. 31, 2 Doc13, p. 1-4

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Transfer

  21. GPR99, a new G protein-coupled receptor with homology to a new subgroup of nucleotide receptors.

    Wittenberger, T., Hellebrand, S., Munck, A., Kreienkamp, H-J., Schaller, H. C. & Hampe, W., 2002, In: BMC GENOMICS. 3, 1, p. 17 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. GTP-induced fusion of isolated pancreatic microsomal vesicles is increased by acidification of the vesicle lumen.

    Hampe, W., Zimmermann, P. & Schulz, I., 1990, In: FEBS LETT. 271, 1-2, p. 62-66 1-2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Guidelines for mouse and human DC functional assays

    Clausen, B., Amon, L., Backer, R., Berod, L., Bopp, T., Brand, A., Burgdorf, S., Chen, L., Da, M., Distler, U., Dress, R. J., Dudziak, D., Dutertre, C-A., Eich, C., Gabele, A., Geiger, M., Ginhoux, F., Giusiano, L., Godoy, G. J., Hamouda, A., Hatscher, L., Heger, L., Heidkamp, G., Hernandez, L. C., Jacobi, L., Kaszubowski, T., Kong, W. T., Lehmann, C., Lopez Lopez, T., Mahnke, K., Nitsche, D., Renkawitz, J., Reza, R., Saez, P., Schlautmann, L., Schmitt, M., Seicher, A., Sielaff, M., Sparwasser, T., Stoitzer, P., Tchitashvili, G., Tenzer, S., Tochoedo, N., Vurnek, D., Zink, F. & Hieronymus, T., 23.12.2023, In: EUR J IMMUNOL. 53, 12, p. e2249925

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Health Literacy: Literature review for the German National Health Literacy Action Plan

    Groene, O., 2016.

    Research output: Working paperResearch communication reports

  25. Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity

    Bartelt, A., Beil, T., Müller, B., Koehne, T., Yorgan, T. A., Heine, M., Yilmaz, T., Ruether, W., Heeren, J., Schinke, T. & Niemeier, A., 01.05.2014, In: BONE. 62, p. 90-98 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis

    Schneegans, S., Löptien, J., Mojzisch, A., Loreth, D., Kretz, O., Raschdorf, C., Hanssen, A., Gocke, A., Siebels, B., Gunasekaran, K., Ding, Y., Oliveira-Ferrer, L., Brylka, L., Schinke, T., Schlüter, H., Paatero, I., Voß, H., Werner, S., Pantel, K. & Wikman, H., 11.04.2024, In: J EXP CLIN CANC RES. 43, 1, p. 110

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Heterogeneous expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase genes in the rat liver lobulus.

    Twisk, J., Hoekman, M. F., Mager, W. H., Moorman, A. F., de Boer, P. A., Scheja, L., Princen, H. M. & Gebhardt, R., 1995, In: J CLIN INVEST. 95, 3, p. 1235-1243 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice

    Rinninger, F., Heine, M., Singaraja, R., Hayden, M., Brundert, M., Ramakrishnan, R. & Heeren, J., 01.09.2014, In: J LIPID RES. 55, 9, p. 1914-1924 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes.

    Heine, M., Freund, B., Nielsen, P., Jung, C., Reimer, R., Hohenberg, H., Zangemeister-Wittke, U., Wester, H-J., Lüers, G. & Schumacher, U., 2012, In: PLOS ONE. 7, 5, p. 36258 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

    Warren, L., Manos, P. D., Ahfeldt, T., Loh, Y-H., Li, H., Lau, F., Ebina, W., Mandal, P. K., Smith, Z. D., Meissner, A., Daley, G. Q., Brack, A. S., Collins, J. J., Cowan, C., Schlaeger, T. M. & Rossi, D. J., 2010, In: CELL STEM CELL. 7, 5, p. 618-630 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. High Metabolic Function and Resilience of NKG2A-Educated NK Cells

    Highton, A. J., Diercks, B-P., Möckl, F., Martrus, G., Sauter, J., Schmidt, A. H., Bunders, M. J., Körner, C., Guse, A. H. & Altfeld, M., 2020, In: FRONT IMMUNOL. 11, 559576.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. High-Resolution Calcium Imaging Method for Local Calcium Signaling

    Diercks, B-P., Werner, R., Schetelig, D., Wolf, I. & Guse, A., 2019, Calcium-Binding Proteins of the EF-Hand Superfamily. 1 ed. Humana Press, Vol. 1929. p. 27-39 13 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  33. High resolution structure of streptavidin in complex with a novel high affinity peptide tag mimicking the biotin binding motif.

    Perbandt, M., Bruns, O., Vallazza, M., Lamla, T., Betzel, C. & Erdmann, V. A., 2007, In: PROTEINS. 67, 4, p. 1147-1153 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Histological Analysis

    Johansson, C. B., Jimbo, R. & Röser, K., 2011, Comprehensive Biomaterials. Ducheyne, P., Healy, K. E., Hutmacher, D. W., Grainger, D. W. & Kirkpatrick, C. J. (eds.). 1 ed. Elsevier Limited, Vol. 3. p. 215-233 19 p. 3.313.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  35. Histological Analysis

    Johansson, C. B., Röser, K., Jimbo, R., Hammarström Johansson, P., Larsson, L. & Östberg, A. K., 2017, Comprehensive Biomaterials II. Ducheyne, P., Healy, K., Hutmacher, D. E., Grainger, D. W. & Kirkpatrick, C. J. (eds.). 2 ed. Oxford, Vol. 3. p. 335-363 29 p. 3.16

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  36. HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation

    Roggenkamp, H. G., Khansahib, I., Hernandez C, L. C., Zhang, Y., Lodygin, D., Krüger, A., Gu, F., Möckl, F., Löhndorf, A., Wolters, V., Woike, D., Rosche, A., Bauche, A., Schetelig, D., Werner, R., Schlüter, H., Failla, A. V., Meier, C., Fliegert, R., Walseth, T. F., Flügel, A., Diercks, B-P. & Guse, A. H., 23.03.2021, In: SCI SIGNAL. 14, 675

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Homepages of German medical faculties--an overview.

    Kuhnigk, O., Tiller, D., Harendza, S. & Hampe, W., 2012, In: GMS Z Med Ausbild. 29, 4, p. 59 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Homozygosity for a partial deletion of apoprotein A-V signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant

    Albers, K., Schlein, C., Wenner, K., Lohse, P., Bartelt, A., Heeren, J., Santer, R. & Merkel, M., 01.03.2014, In: ATHEROSCLEROSIS. 233, 1, p. 97-103 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Host cell responses to Chlamydia pneumoniae in gamma interferon-induced persistence overlap those of productive infection and are linked to genes involved in apoptosis, cell cycle, and metabolism.

    Eickhoff, M., Thalmann, J., Hess, S., Martin, M., Laue, T., Kruppa, J., Brandes, G. & Klos, A., 2007, In: INFECT IMMUN. 75, 6, p. 2853-2863 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. How good are medical students at communicating risk? An implementation study at three German medical schools

    Groene, O., Bergelt, C. & Ehrhardt, M., 01.2022, In: PATIENT EDUC COUNS. 105, 1, p. 128-135 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Hu-K4 is a ubiquitously expressed type 2 transmembrane protein associated with the endoplasmic reticulum.

    Munck, A., Böhm, C., Seibel, N. M., Zara, H. H. & Hampe, W., 2005, In: FEBS J. 272, 7, p. 1718-1726 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo.

    Dieckmann, M., Beil, F. T., Müller, B., Bartelt, A., Marshall, R. P., Köhne, T., Amling, M., Ruether, W., Cooper, J. A., Humphries, S. E., Herz, J. & Niemeier, A., 2013, In: J BONE MINER RES. 28, 2, p. 236-245 10 p., 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Human beta 2-adrenergic receptor produced in stably transformed insect cells is functionally coupled via endogenous GTP-binding protein to adenylyl cyclase.

    Kleymann, G., Boege, F., Hahn, M., Hampe, W., Vasudevan, S. & Reiländer, H., 1993, In: EUR J BIOCHEM. 213, 2, p. 797-804 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Human dental pulp cells modulate CD8+ T cell proliferation and efficiently degrade extracellular ATP to adenosine in vitro

    Ahmadi, P., Yan, M., Bauche, A., Smeets, R., Müller, C. E., Koch-Nolte, F., Haag, F., Fliegert, R., Kluwe, L., Schulze Zur Wiesch, J. & Hartjen, P., 10.2022, In: CELL IMMUNOL. 380, 104589.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Human Fetal TNF-α-Cytokine-Producing CD4 Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life

    Schreurs, R. R. C. E., Baumdick, M. E., Sagebiel, A. F., Kaufmann, M., Mokry, M., Klarenbeek, P. L., Schaltenberg, N., Steinert, F. L., van Rijn, J. M., Drewniak, A., The, S-M. M. L., Bakx, R., Derikx, J. P. M., de Vries, N., Corpeleijn, W. E., Pals, S. T., Gagliani, N., Friese, M. A., Middendorp, S., Nieuwenhuis, E. E. S., Reinshagen, K., Geijtenbeek, T. B. H., van Goudoever, J. B. & Bunders, M. J., 19.02.2019, In: IMMUNITY. 50, 2, p. 462-476.e8

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Human mesenchymal stem cells are not of donor origin in patients with severe aplastic anemia who underwent sex-mismatched allogeneic bone marrow transplant

    Stute, N., Fehse, B., Schröder, J., Arps, S., Adamietz, P., Held, K. R. & Zander, A. R., 12.2002, In: J HEMATOTH STEM CELL. 11, 6, p. 977-984 8 p.

    Research output: SCORING: Contribution to journalShort publicationResearchpeer-review

  47. Hydrolysis and rearrangement reactions of riboflavin phosphates. An explicit kinetic study.

    Nielsen, P., Harksen, J. & Bacher, A., 1985, In: EUR J BIOCHEM. 152, 2, p. 465-473 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Hypertriglyceridemia in obese subjects: caused by reduced apolipoprotein A5 plasma levels?

    Heeren, J. & Merkel, M., 2010, In: ATHEROSCLEROSIS. 212, 2, p. 386-387 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Identification and characterization of SorCS, a third member of a novel receptor family.

    Hermey, G., Riedel, I. B., Hampe, W., Schaller, H. C. & Hermans-Borgmeyer, I., 1999, In: BIOCHEM BIOPH RES CO. 266, 2, p. 347-351 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Identification of a cis-acting element and a novel trans-acting factor of the glutamine synthetase gene in liver cells.

    Gaunitz, F., Weber, S., Scheja, L. & Gebhardt, R., 2001, In: BIOCHEM BIOPH RES CO. 284, 2, p. 377-383 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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