Department of Pediatric Hematology and Oncology
Publications
- 2022
Patient-level proteomic network prediction by explainable artificial intelligence
Keyl, P., Michael, B., Heim, D., Dernbach, G., Montavon, G., Müller, K-R. & Klauschen, F., 07.06.2022, In: NPJ PRECIS ONCOL. 6, 1, 35.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance
Federico, A., Thomas, C., Miskiewicz, K., Woltering, N., Zin, F., Nemes, K., Bison, B., Johann, P. D., Hawes, D., Bens, S., Kordes, U., Albrecht, S., Dohmen, H., Hauser, P., Keyvani, K., van Landeghem, F. K. H., Lund, E. L., Scheie, D., Mawrin, C., Monoranu, C-M., Parm Ulhøi, B., Pietsch, T., Reinhard, H., Riemenschneider, M. J., Sehested, A., Sumerauer, D., Siebert, R., Paulus, W., Frühwald, M. C., Kool, M. & Hasselblatt, M., 06.2022, In: ACTA NEUROPATHOL. 143, 6, p. 697-711 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC
Hasselblatt, M., Thomas, C., Federico, A., Bens, S., Hellström, M., Casar-Borota, O., Kordes, U., Neumann, J. E., Dottermusch, M., Rodriguez, F. J., Lo, A. C., Cheng, S., Hendson, G., Hukin, J., Hartmann, C., Koch, A., Capper, D., Siebert, R., Paulus, W., Nemes, K., Johann, P. D., Frühwald, M. C. & Kool, M., 06.2022, In: NEUROPATH APPL NEURO. 48, 4, p. e12797 e12797.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MODL-03. Establishment of intraventricular Shh inhibition as a therapeutic option for young patients with medulloblastoma
Kresbach, C., Schoof, M., Holst, L., Leven, T., Yorgan, T. A., Wrzeszcz, A., Rutkowski, S. J. & Schüller, U., 06.2022, In: NEURO-ONCOLOGY. 24, S1, p. i168Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review
Looking back: Identifying supportive care and unmet needs of parents of children receiving specialist paediatric palliative care from the bereavement perspective
Bronsema, A., Theißen, T., Oechsle, K., Wikert, J., Escherich, G., Rutkowski, S., Bokemeyer, C. & Ullrich, A., 25.05.2022, In: BMC PALLIAT CARE. 21, 1, 87.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long noncoding RNAs as regulators of pediatric acute myeloid leukemia
Neyazi, S., Ng, M., Heckl, D. & Klusmann, J-H., 20.05.2022, In: Molecular and cellular pediatrics. 9, 1, 10.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol
Toksvang, L. N., Als-Nielsen, B., Bacon, C., Bertasiute, R., Duarte, X., Escherich, G., Helgadottir, E. A., Johannsdottir, I. R., Jónsson, Ó. G., Kozlowski, P., Langenskjöld, C., Lepik, K., Niinimäki, R., Overgaard, U. M., Punab, M., Räty, R., Segers, H., van der Sluis, I., Smith, O. P., Strullu, M., Vaitkevičienė, G., Wik, H. S., Heyman, M. & Schmiegelow, K., 02.05.2022, In: BMC CANCER. 22, 1, 483.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acute Lymphoblastic Leukemia Study Group
Escherich, G., Zur Stadt, U., Borkhardt, A., Dilloo, D., Faber, J., Feuchtinger, T., Imschweiler, T., Jorch, N., Pekrun, A., Schmid, I., Schramm, F., Spohn, M., Zimmermann, M. & Horstmann, M. A., 01.05.2022, In: HAEMATOLOGICA. 107, 5, p. 1026-1033 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults
Hines, M. R., von Bahr Greenwood, T., Beutel, G., Beutel, K., Hays, J. A., Horne, A., Janka, G., Jordan, M. B., van Laar, J. A. M., Lachmann, G., Lehmberg, K., Machowicz, R., Miettunen, P., La Rosée, P., Shakoory, B., Zinter, M. S. & Henter, J-I., 01.05.2022, In: CRIT CARE MED. 50, 5, p. 860-872 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Does the Y chromosome play a role for outcome in childhood acute lymphoblastic leukemia?
Conter, V., Schrappe, M. & Escherich, G., 01.05.2022, In: CANCER-AM CANCER SOC. 128, 9, p. 1727-1729 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Allogeneic hematopoietic stem cell transplantation for adult HLH: a retrospective study by the chronic malignancies and inborn errors working parties of EBMT
Machowicz, R., Suarez, F., Wiktor-Jedrzejczak, W., Eikema, D-J., de Wreede, L. C., Blok, H-J., Isaksson, C., Einsele, H., Poiré, X., van Dorp, S., Nikolousis, E., Johansson, J-E., Kobbe, G., Zecca, M., Arnold, R., Gerbitz, A., Finke, J., Díez-Martín, J. L., Bonifazi, F., McQuaker, G., Lenhoff, S., Rohrlich, P-S., Theobald, M., Ljungman, P., Collin, M., Albert, M. H., Ehninger, G., Carlson, K., Halaburda, K., Lehmberg, K., Schönland, S., Yakoub-Agha, I., Gennery, A. R., Lankester, A. C. & Kröger, N., 05.2022, In: BONE MARROW TRANSPL. 57, 5, p. 817-823 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of single copy gene‑based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19‑directed CAR T cells in treated patients
Schubert, M-L., Berger, C., Kunz, A., Schmitt, A., Badbaran, A., Neuber, B., Zeschke, S., Wang, L., Riecken, K., Hückelhoven-Krauss, A., Müller, I., Müller-Tidow, C., Dreger, P., Kröger, N., Ayuk, F. A., Schmitt, M. & Fehse, B., 05.2022, In: INT J ONCOL. 60, 5, 48.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population
Nemes, K., Johann, P. D., Steinbügl, M., Gruhle, M., Bens, S., Kachanov, D., Teleshova, M., Hauser, P., Simon, T., Tippelt, S., Eberl, W., Chada, M., Lopez, V. S-M., Grigull, L., Hernáiz-Driever, P., Eyrich, M., Pears, J., Milde, T., Reinhard, H., Leipold, A., van de Wetering, M., Gil-da-Costa, M. J., Ebetsberger-Dachs, G., Kerl, K., Lemmer, A., Boztug, H., Furtwängler, R., Kordes, U., Vokuhl, C., Hasselblatt, M., Bison, B., Kröncke, T., Melchior, P., Timmermann, B., Gerss, J., Siebert, R. & Frühwald, M. C., 27.04.2022, In: CANCERS. 14, 9, 2185.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Children with cancer and their families after active treatment: analyses of biopsychosocial needs and implications for healthcare - a study protocol
Inhestern, L., Paul, V., Winzig, J., Rutkowski, S., Escherich, G. & Bergelt, C., 05.04.2022, In: BMJ OPEN. 12, 4, p. e055633Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Can Machine Learning Models Predict Asparaginase-associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia
Nielsen, R. L., Wolthers, B. O., Helenius, M., Albertsen, B. K., Clemmensen, L., Nielsen, K., Kanerva, J., Niinimäki, R., Frandsen, T. L., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Aytan-Aktug, D., Liu, H-C., Möricke, A., Samarasinghe, S., van der Sluis, I. M., Stanulla, M., Tulstrup, M., Yadav, R., Zapotocka, E., Schmiegelow, K. & Gupta, R., 01.04.2022, In: J PEDIAT HEMATOL ONC. 44, 3, p. e628-e636Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hematopoietic Stem Cell Transplantation with Mesenchymal Stromal Cells in Children with Metachromatic Leukodystrophy
Cabanillas Stanchi, K. M., Böhringer, J., Strölin, M., Groeschel, S., Lenglinger, K., Treuner, C., Kehrer, C., Laugwitz, L., Bevot, A., Kaiser, N., Schumm, M., Lang, P., Handgretinger, R., Krägeloh-Mann, I., Müller, I. & Döring, M., 04.2022, In: STEM CELLS DEV. 31, 7-8, p. 163-175 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Machine Learning Models Predict the Primary Sites of Head and Neck Squamous Cell Carcinoma Metastases Based on DNA Methylation
Leitheiser, M., Capper, D., Seegerer, P., Lehmann, A., Schüller, U., Müller, K-R., Klauschen, F., Jurmeister, P. & Michael, B., 04.2022, In: J PATHOL. 256, 4, p. 378-387 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mucha-Habermann disease: a pediatric case report and proposal of a risk score
Blohm, M. E., Ebenebe, C. U., Rau, C., Escherich, C., Johannsen, J., Escherich, G., Driemeyer, J., Nagel, P. D., Kobbe, R., Lütgehetmann, M., Lennartz, M., Booken, N., Schneider, S. W. & Singer, D., 04.2022, In: INT J DERMATOL. 61, 4, p. 401-409 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Spatial molecular profiling of a central nervous system low-grade diffusely infiltrative tumour with INI1 deficiency featuring a high-grade atypical teratoid/rhabdoid tumour component
Dottermusch, M., Schumann, Y., Kordes, U., Hasselblatt, M. & Neumann, J. E., 04.2022, In: NEUROPATH APPL NEURO. 48, 3, p. e12777 e12777.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Quantification of Minimal Disease by Digital PCR in ALK-Positive Anaplastic Large Cell Lymphoma: A Step towards Risk Stratification in International Trials?
Damm-Welk, C., Lovisa, F., Contarini, G., Lüdersen, J., Carraro, E., Knörr, F., Förster, J., Zimmermann, M., Sala, A., Vinti, L., Tondo, A., Pillon, M., Woessmann, W. & Mussolin, L., 27.03.2022, In: CANCERS. 14, 7, 1703.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Remission, treatment failure, and relapse in pediatric ALL: An international consensus of the Ponte-di-Legno Consortium
Buchmann, S., Schrappe, M., Baruchel, A., Biondi, A., Borowitz, M. J., Campbell, M., Cario, G., Cazzaniga, G., Escherich, G., Harrison, C. J., Heyman, M., Hunger, S. P., Kiss, C., Liu, H-C., Locatelli, F., Loh, M. L., Manabe, A., Mann, G., Pieters, R., Pui, C-H., Rives, S., Schmiegelow, K., Silverman, L. B., Stary, J., Vora, A., Brown, P. A. & Ponte-di-Legno Consortium, 24.03.2022, In: BLOOD. 139, 12, p. 1785-1793 9 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors
Graf, M., Interlandi, M., Moreno, N., Holdhof, D., Göbel, C., Melcher, V., Mertins, J., Albert, T. K., Kastrati, D., Alfert, A., Holsten, T., de Faria, F., Meisterernst, M., Rossig, C., Warmuth-Metz, M., Nowak, J., Meyer Zu Hörste, G., Mayère, C., Nef, S., Johann, P., Frühwald, M. C., Dugas, M., Schüller, U. & Kerl, K., 22.03.2022, In: NAT COMMUN. 13, 1, 1544.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Reconstitution Dynamics of Cultivated Hematopoietic Stem Cells and Progenitors Is Independent of Age
Gotzhein, F., Aranyossy, T., Thielecke, L., Sonntag, T., Thaden, V., Fehse, B., Müller, I., Glauche, I. & Cornils, K., 15.03.2022, In: INT J MOL SCI. 23, 6, 3160.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased replication stress and R-loop accumulation in EGFRvIII expressing glioblastoma present new therapeutic opportunities
Struve, N., Hoffer, K., Weik, A-S., Riepen, B., Krug, L., Cetin, M. H., Burmester, J., Ott, L., Liebing, J., Gatzemeier, F., Müller-Goebel, J., Bußmann, L., Parplys, A. C., Unger, K., Mansour, W. Y., Schüller, U., Rieckmann, T., Petersen, C., Rothkamm, K., Short, S. C. & Kriegs, M., 12.03.2022, In: NEURO-ONCOL ADV. 4, 1, p. vdab180 vdab180.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influence of Fetomaternal Microchimerism on Maternal NK Cell Reactivity against the Child's Leukemic Blasts
Martin, L-M., Kruchen, A., Fehse, B. & Müller, I., 04.03.2022, In: BIOMEDICINES. 10, 3, 603.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A new amplicon-based gene panel for next generation sequencing characterization of meningiomas
Mawrin, C., Koch, R., Waldt, N., Sandalcioglu, I. E., Braunsdorf, W. K., Warnke, J-P., Goehre, F., Meisel, H-J., Ewald, C., Neyazi, S., Schüller, U. & Kirches, E., 03.2022, In: BRAIN PATHOL. 32, 2, e13046.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Clinical and molecular characterization of isolated M1 disease in pediatric medulloblastoma: experience from the German HIT-MED studies
Obrecht, D., Mynarek, M., Hagel, C., Kwiecien, R., Spohn, M., Bockmayr, M., Bison, B., Pfister, S. M., Jones, D. T. W., Sturm, D., von Deimling, A., Sahm, F., von Hoff, K., Juhnke, B-O., Benesch, M., Gerber, N. U., Friedrich, C., von Bueren, A. O., Kortmann, R-D., Schwarz, R., Pietsch, T., Fleischhack, G., Schüller, U. & Rutkowski, S., 03.2022, In: J NEURO-ONCOL. 157, 1, p. 37-48 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma
Hohm, A., Karremann, M., Gielen, G. H., Pietsch, T., Warmuth-Metz, M., Vandergrift, L. A., Bison, B., Stock, A., Hoffmann, M., Pham, M., Kramm, C. M. & Nowak, J., 03.2022, In: CLIN NEURORADIOL. 32, 1, p. 249-258 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Refining M1 stage in medulloblastoma: criteria for cerebrospinal fluid cytology and implications for improved risk stratification from the HIT-2000 trial
Hagel, C., Sloman, V., Mynarek, M., Petrasch, K., Obrecht, D., Kühl, J., Deinlein, F., Schmid, R., von Bueren, A. O., Friedrich, C., Juhnke, B. O., Gerber, N. U., Kwiecien, R., Girschick, H., Höller, A., Zapf, A., von Hoff, K. & Rutkowski, S., 03.2022, In: EUR J CANCER. 164, p. 30-38Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Types of deviation and review criteria in pretreatment central quality control of tumor bed boost in medulloblastoma-an analysis of the German Radiotherapy Quality Control Panel in the SIOP PNET5 MB trial
Dietzsch, S., Braesigk, A., Seidel, C., Remmele, J., Kitzing, R., Schlender, T., Mynarek, M., Geismar, D., Jablonska, K., Schwarz, R., Pazos, M., Weber, D. C., Frick, S., Gurtner, K., Matuschek, C., Harrabi, S. B., Glück, A., Lewitzki, V., Dieckmann, K., Benesch, M., Gerber, N. U., Obrecht, D., Rutkowski, S., Timmermann, B. & Kortmann, R-D., 03.2022, In: STRAHLENTHER ONKOL. 198, 3, p. 282-290 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multimodal Treatment of Nasopharyngeal Carcinoma in Children, Adolescents and Young Adults-Extended Follow-Up of the NPC-2003-GPOH Study Cohort and Patients of the Interim Cohort
Römer, T., Franzen, S., Kravets, H., Farrag, A., Makowska, A., Christiansen, H., Eble, M. J., Timmermann, B., Staatz, G., Mottaghy, F. M., Bührlen, M., Hagenah, U., Puzik, A., Driever, P. H., Greiner, J., Jorch, N., Tippelt, S., Schneider, D. T., Kropshofer, G., Overbeck, T. R., Christiansen, H., Brozou, T., Escherich, G., Becker, M., Friesenbichler, W., Feuchtinger, T., Puppe, W., Heussen, N., Hilgers, R. D. & Kontny, U., 28.02.2022, In: CANCERS. 14, 5, 1261.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Akute lymphoblastische Leukämie
Escherich, G., Möricke, A., Horstmann, M. & Schrappe, M., 15.02.2022, Kompendium Internistische Onkologie: Standards in Diagnostik und Therapie. Schmoll, H-J. (ed.). 5 ed. Berlin, Heidelberg: Springer, 11 p.Research output: SCORING: Contribution to book/anthology › Chapter › Research › peer-review
NET Release of Long-Term Surviving Neutrophils
Kolman, J. P., Pagerols Raluy, L., Müller, I., Nikolaev, V., Trochimiuk, M., Appl, B., Wadehn, H., Dücker, C., Stoll, F., Boettcher, M., Reinshagen, K. & Trah, J., 15.02.2022, In: FRONT IMMUNOL. 13, p. 815412 815412.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Primary central nervous system sarcoma with DICER1 mutation-treatment results of a novel molecular entity in pediatric Peruvian patients
Diaz Coronado, R. Y., Mynarek, M., Koelsche, C., Mora Alferez, P., Casavilca Zambrano, S., Wachtel Aptowitzer, A., Sahm, F., von Deimling, A., Schüller, U., Spohn, M., Sturm, D., Pfister, S. M., Morales La Madrid, A., Sernaque Quintana, R., Sarria Bardales, G., Negreiros Chinchihuara, T., Ojeda Medina, L., Garcia-Corrochano Medina, P., Campos Sanchez, D. A., Ponce Farfan, J., Rutkowski, S. & Garcia Leon, J. L., 15.02.2022, In: CANCER-AM CANCER SOC. 128, 4, p. 697-707 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma
Lechner, M., Takahashi, Y., Turri-Zanoni, M., Liu, J., Counsell, N., Hermsen, M., Kaur, R. P., Zhao, T., Ramanathan, M., Schartinger, V. H., Emanuel, O., Helman, S., Varghese, J., Dudas, J., Riechelmann, H., Sprung, S., Haybaeck, J., Howard, D., Engel, N. W., Stewart, S., Brooks, L., Pickles, J. C., Jacques, T. S., Fenton, T. R., Williams, L., Vaz, F. M., O'Flynn, P., Stimpson, P., Wang, S., Hannan, S. A., Unadkat, S., Hughes, J., Dwivedi, R., Forde, C. T., Randhawa, P., Gane, S., Joseph, J., Andrews, P. J., Royle, G., Franchi, A., Maragliano, R., Battocchio, S., Bewicke-Copley, H., Pipinikas, C., Webster, A., Thirlwell, C., Ho, D., Teschendorff, A., Zhu, T., Steele, C. D., Pillay, N., Vanhaesebroeck, B., Mohyeldin, A., Fernandez-Miranda, J., Park, K. W., Le, Q-T., West, R. B., Saade, R., Manes, R. P., Omay, S. B., Vining, E. M., Judson, B. L., Yarbrough, W. G., Sansovini, M., Silvia, N., Grassi, I., Bongiovanni, A., Capper, D., Schüller, U., Thavaraj, S., Sandison, A., Surda, P., Hopkins, C., Ferrari, M., Mattavelli, D., Rampinelli, V., Facchetti, F., Nicolai, P., Bossi, P., Henriquez, O. A., Magliocca, K., Solares, C. A., Wise, S. K., Llorente, J. L., Patel, Z. M., Nayak, J. V., Hwang, P. H., Lacy, P. D., Woods, R., O'Neill, J. P., Jay, A., Carnell, D., Forster, M. D., Ishii, M., London, N. R., Bell, D. M., Gallia, G. L., Castelnuovo, P., Severi, S., Lund, V. J. & Hanna, E. Y., 02.2022, In: EUR J CANCER. 162, p. 221-236 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Final results of the Choroid Plexus Tumor study CPT-SIOP-2000
Wolff, J. E., Van Gool, S. W., Kutluk, T., Diez, B., Kebudi, R., Timmermann, B., Garami, M., Sterba, J., Fuller, G. N., Bison, B. & Kordes, U. R., 02.2022, In: J NEURO-ONCOL. 156, 3, p. 599-613 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Gain-of-function variant p.Pro2555Arg of von Willebrand factor increases aggregate size through altering stem dynamics
Huck, V., Chen, P-C., Xu, E-R., Tischer, A., Klemm, U., Aponte-Santamaría, C., Mess, C., Obser, T., Kutzki, F., König, G., Denis, C., Gräter, F., Wilmanns, M., Auton, M., Schneider, S. W., Schneppenheim, R., Hennig, J. & Brehm, M. A., 02.2022, In: THROMB HAEMOSTASIS. 122, 2, p. 226-239 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hypersensitivity to Pegylated E.colia sparaginase as first-line treatment in contemporary paediatric acute lymphoblastic leukaemia protocols: a meta-analysis of the Ponte di Legno Toxicity working group
Brigitha, L. J., Fiocco, M., Pieters, R., Albertsen, B. K., Escherich, G., Lopez-Lopez, E., Mondelaers, V., Vora, A., Vrooman, L., Schmiegelow, K., van der Sluis, I. M. & Ponte di Legno toxicity working group, 02.2022, In: EUR J CANCER. 162, p. 65-75 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Long-term survival of an adolescent glioblastoma patient under treatment with vinblastine and valproic acid illustrates importance of methylation profiling
Kresbach, C., Bronsema, A., Guerreiro, H., Rutkowski, S., Schüller, U. & Winkler, B., 02.2022, In: CHILD NERV SYST. 38, 2, p. 479-483 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Maternal versus paternal living kidney transplant donation is associated with lower rejection in young pediatric recipients: A Collaborative Transplant Study report
Engels, G., Döhler, B., Tönshoff, B., Oh, J., Kruchen, A., Müller, I. & Süsal, C., 02.2022, In: PEDIATR TRANSPLANT. 26, 1, e14154.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Local and Systemic Therapy of Recurrent Medulloblastomas in Children and Adolescents: Results of the P-HIT-REZ 2005 Study
Gaab, C., Adolph, J. E., Tippelt, S., Mikasch, R., Obrecht, D., Mynarek, M., Rutkowski, S., Pfister, S. M., Milde, T., Witt, O., Bison, B., Warmuth-Metz, M., Kortmann, R-D., Dietzsch, S., Pietsch, T., Timmermann, B., Sträter, R., Bode, U., Faldum, A., Kwiecien, R. & Fleischhack, G., 18.01.2022, In: CANCERS. 14, 3, 471.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial
Bailey, S., André, N., Gandola, L., Massimino, M., Rutkowski, S. & Clifford, S. C., 13.01.2022, In: CANCERS. 14, 2, 374.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and high-dose chemotherapy within the prospective P-HIT trial
Juhnke, B-O., Gessi, M., Gerber, N. U., Friedrich, C., Mynarek, M., von Bueren, A. O., Haberler, C., Schüller, U., Kortmann, R-D., Timmermann, B., Bison, B., Warmuth-Metz, M., Kwiecien, R., Pfister, S. M., Spix, C., Pietsch, T., Kool, M., Rutkowski, S. & von Hoff, K., 05.01.2022, In: NEURO-ONCOLOGY. 24, 1, p. 127-137 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency
Das, A., Sudhaman, S., Morgenstern, D., Coblentz, A., Chung, J., Stone, S. C., Alsafwani, N., Liu, Z. A., Karsaneh, O. A. A., Soleimani, S., Ladany, H., Chen, D., Zatzman, M., Cabric, V., Nobre, L., Bianchi, V., Edwards, M., Sambira Nahum, L. C., Ercan, A. B., Nabbi, A., Constantini, S., Dvir, R., Yalon-Oren, M., Campino, G. A., Caspi, S., Larouche, V., Reddy, A., Osborn, M., Mason, G., Lindhorst, S., Bronsema, A., Magimairajan, V., Opocher, E., De Mola, R. L., Sabel, M., Frojd, C., Sumerauer, D., Samuel, D., Cole, K., Chiaravalli, S., Massimino, M., Tomboc, P., Ziegler, D. S., George, B., Van Damme, A., Hijiya, N., Gass, D., McGee, R. B., Mordechai, O., Bowers, D. C., Laetsch, T. W., Lossos, A., Blumenthal, D. T., Sarosiek, T., Yen, L. Y., Knipstein, J., Bendel, A., Hoffman, L. M., Luna-Fineman, S., Zimmermann, S., Scheers, I., Nichols, K. E., Zapotocky, M., Hansford, J. R., Maris, J. M., Dirks, P., Taylor, M. D., Kulkarni, A. V., Shroff, M., Tsang, D. S., Villani, A., Xu, W., Aronson, M., Durno, C., Shlien, A., Malkin, D., Getz, G., Maruvka, Y. E., Ohashi, P. S., Hawkins, C., Pugh, T. J., Bouffet, E. & Tabori, U., 01.2022, In: NAT MED. 28, 1, p. 125-135 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD
Arnold, D. E., Nofal, R., Wakefield, C., Lehmberg, K., Wustrau, K., Albert, M. H., Morris, E. C., Heimall, J. R., Bunin, N. J., Kumar, A., Jordan, M. B., Cole, T., Choo, S., Brettig, T., Speckmann, C., Ehl, S., Salamonowicz, M., Wahlstrom, J., Rao, K., Booth, C., Worth, A. & Marsh, R. A., 01.2022, In: J CLIN IMMUNOL. 42, 1, p. 36-45 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity
Groß, M., Speckmann, C., May, A., Gajardo-Carrasco, T., Wustrau, K., Maier, S. L., Panning, M., Huzly, D., Agaimy, A., Bryceson, Y. T., Choo, S., Chow, C. W., Dückers, G., Fasth, A., Fraitag, S., Gräwe, K., Haxelmans, S., Holzinger, D., Hudowenz, O., Hübschen, J. M., Khurana, C., Kienle, K., Klifa, R., Korn, K., Kutzner, H., Lämmermann, T., Ledig, S., Lipsker, D., Meeths, M., Naumann-Bartsch, N., Rascon, J., Schänzer, A., Seidl, M., Tesi, B., Vauloup-Fellous, C., Vollmer-Kary, B., Warnatz, K., Wehr, C., Neven, B., Vargas, P., Sepulveda, F. E., Lehmberg, K., Schmitt-Graeff, A. & Ehl, S., 01.2022, In: J ALLERGY CLIN IMMUN. 149, 1, p. 388-399.e4Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Relapsed Medulloblastoma in Pre-Irradiated Patients: Current Practice for Diagnostics and Treatment
Hill, R. M., Plasschaert, S. L. A., Timmermann, B., Dufour, C., Aquilina, K., Avula, S., Donovan, L., Lequin, M., Pietsch, T., Thomale, U., Tippelt, S., Wesseling, P., Rutkowski, S., Clifford, S. C., Pfister, S. M., Bailey, S. & Fleischhack, G., 28.12.2021, In: CANCERS. 14, 1, 126.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Ex vivo testis explant culture of human testicular tissue
Aden, N. L., Soave, A., Kordes, U., Bleeke, M., Salzbrunn, A. & von Kopylow, K., 05.12.2021, In: J Reprodmed Endokrinol. 2020, 17 (Supplementum 1), 39-40Research output: SCORING: Contribution to journal › Conference abstract in journal › Research
SIOP PNET5 MB Trial: History and Concept of a Molecularly Stratified Clinical Trial of Risk-Adapted Therapies for Standard-Risk Medulloblastoma
Mynarek, M., Milde, T., Padovani, L., Janssens, G. O., Kwiecien, R., Mosseri, V., Clifford, S. C., Doz, F. & Rutkowski, S., 02.12.2021, In: CANCERS. 13, 23, 1677.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Dose-adjusted EPOCH-rituximab or intensified B-NHL therapy for pediatric primary mediastinal large B-cell lymphoma
Knörr, F., Zimmermann, M., Attarbaschi, A., Kabickova, E., Maecker-Kolhoff, B., Ruf, S., Kühnle, I., Ebinger, M., Garthe, A-K., Simonitsch-Klupp, I., Oschlies, I., Klapper, W., Burkhardt, B. & Wößmann, W., 01.12.2021, In: HAEMATOLOGICA. 106, 12, p. 3232-3235 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research