Research ExplorerResearch UnitsDepartment of Pediatric Hematology and Oncology Publications

Department of Pediatric Hematology and Oncology

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Publications

  1. 2022

  2. Patient-level proteomic network prediction by explainable artificial intelligence

    Keyl, P., Michael, B., Heim, D., Dernbach, G., Montavon, G., Müller, K-R. & Klauschen, F., 07.06.2022, In: NPJ PRECIS ONCOL. 6, 1, 35.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. ATRT-SHH comprises three molecular subgroups with characteristic clinical and histopathological features and prognostic significance

    Federico, A., Thomas, C., Miskiewicz, K., Woltering, N., Zin, F., Nemes, K., Bison, B., Johann, P. D., Hawes, D., Bens, S., Kordes, U., Albrecht, S., Dohmen, H., Hauser, P., Keyvani, K., van Landeghem, F. K. H., Lund, E. L., Scheie, D., Mawrin, C., Monoranu, C-M., Parm Ulhøi, B., Pietsch, T., Reinhard, H., Riemenschneider, M. J., Sehested, A., Sumerauer, D., Siebert, R., Paulus, W., Frühwald, M. C., Kool, M. & Hasselblatt, M., 06.2022, In: ACTA NEUROPATHOL. 143, 6, p. 697-711 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC

    Hasselblatt, M., Thomas, C., Federico, A., Bens, S., Hellström, M., Casar-Borota, O., Kordes, U., Neumann, J. E., Dottermusch, M., Rodriguez, F. J., Lo, A. C., Cheng, S., Hendson, G., Hukin, J., Hartmann, C., Koch, A., Capper, D., Siebert, R., Paulus, W., Nemes, K., Johann, P. D., Frühwald, M. C. & Kool, M., 06.2022, In: NEUROPATH APPL NEURO. 48, 4, p. e12797 e12797.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. MODL-03. Establishment of intraventricular Shh inhibition as a therapeutic option for young patients with medulloblastoma

    Kresbach, C., Schoof, M., Holst, L., Leven, T., Yorgan, T. A., Wrzeszcz, A., Rutkowski, S. J. & Schüller, U., 06.2022, In: NEURO-ONCOLOGY. 24, S1, p. i168

    Research output: SCORING: Contribution to journal › Conference abstract in journal › Research › peer-review

  6. Looking back: Identifying supportive care and unmet needs of parents of children receiving specialist paediatric palliative care from the bereavement perspective

    Bronsema, A., Theißen, T., Oechsle, K., Wikert, J., Escherich, G., Rutkowski, S., Bokemeyer, C. & Ullrich, A., 25.05.2022, In: BMC PALLIAT CARE. 21, 1, 87.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Long noncoding RNAs as regulators of pediatric acute myeloid leukemia

    Neyazi, S., Ng, M., Heckl, D. & Klusmann, J-H., 20.05.2022, In: Molecular and cellular pediatrics. 9, 1, 10.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  8. Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol

    Toksvang, L. N., Als-Nielsen, B., Bacon, C., Bertasiute, R., Duarte, X., Escherich, G., Helgadottir, E. A., Johannsdottir, I. R., Jónsson, Ó. G., Kozlowski, P., Langenskjöld, C., Lepik, K., Niinimäki, R., Overgaard, U. M., Punab, M., Räty, R., Segers, H., van der Sluis, I., Smith, O. P., Strullu, M., Vaitkevičienė, G., Wik, H. S., Heyman, M. & Schmiegelow, K., 02.05.2022, In: BMC CANCER. 22, 1, 483.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acute Lymphoblastic Leukemia Study Group

    Escherich, G., Zur Stadt, U., Borkhardt, A., Dilloo, D., Faber, J., Feuchtinger, T., Imschweiler, T., Jorch, N., Pekrun, A., Schmid, I., Schramm, F., Spohn, M., Zimmermann, M. & Horstmann, M. A., 01.05.2022, In: HAEMATOLOGICA. 107, 5, p. 1026-1033 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults

    Hines, M. R., von Bahr Greenwood, T., Beutel, G., Beutel, K., Hays, J. A., Horne, A., Janka, G., Jordan, M. B., van Laar, J. A. M., Lachmann, G., Lehmberg, K., Machowicz, R., Miettunen, P., La Rosée, P., Shakoory, B., Zinter, M. S. & Henter, J-I., 01.05.2022, In: CRIT CARE MED. 50, 5, p. 860-872 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  11. Does the Y chromosome play a role for outcome in childhood acute lymphoblastic leukemia?

    Conter, V., Schrappe, M. & Escherich, G., 01.05.2022, In: CANCER-AM CANCER SOC. 128, 9, p. 1727-1729 3 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  12. Allogeneic hematopoietic stem cell transplantation for adult HLH: a retrospective study by the chronic malignancies and inborn errors working parties of EBMT

    Machowicz, R., Suarez, F., Wiktor-Jedrzejczak, W., Eikema, D-J., de Wreede, L. C., Blok, H-J., Isaksson, C., Einsele, H., Poiré, X., van Dorp, S., Nikolousis, E., Johansson, J-E., Kobbe, G., Zecca, M., Arnold, R., Gerbitz, A., Finke, J., Díez-Martín, J. L., Bonifazi, F., McQuaker, G., Lenhoff, S., Rohrlich, P-S., Theobald, M., Ljungman, P., Collin, M., Albert, M. H., Ehninger, G., Carlson, K., Halaburda, K., Lehmberg, K., Schönland, S., Yakoub-Agha, I., Gennery, A. R., Lankester, A. C. & Kröger, N., 05.2022, In: BONE MARROW TRANSPL. 57, 5, p. 817-823 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Comparison of single copy gene‑based duplex quantitative PCR and digital droplet PCR for monitoring of expansion of CD19‑directed CAR T cells in treated patients

    Schubert, M-L., Berger, C., Kunz, A., Schmitt, A., Badbaran, A., Neuber, B., Zeschke, S., Wang, L., Riecken, K., Hückelhoven-Krauss, A., Müller, I., Müller-Tidow, C., Dreger, P., Kröger, N., Ayuk, F. A., Schmitt, M. & Fehse, B., 05.2022, In: INT J ONCOL. 60, 5, 48.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population

    Nemes, K., Johann, P. D., Steinbügl, M., Gruhle, M., Bens, S., Kachanov, D., Teleshova, M., Hauser, P., Simon, T., Tippelt, S., Eberl, W., Chada, M., Lopez, V. S-M., Grigull, L., Hernáiz-Driever, P., Eyrich, M., Pears, J., Milde, T., Reinhard, H., Leipold, A., van de Wetering, M., Gil-da-Costa, M. J., Ebetsberger-Dachs, G., Kerl, K., Lemmer, A., Boztug, H., Furtwängler, R., Kordes, U., Vokuhl, C., Hasselblatt, M., Bison, B., Kröncke, T., Melchior, P., Timmermann, B., Gerss, J., Siebert, R. & Frühwald, M. C., 27.04.2022, In: CANCERS. 14, 9, 2185.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Children with cancer and their families after active treatment: analyses of biopsychosocial needs and implications for healthcare - a study protocol

    Inhestern, L., Paul, V., Winzig, J., Rutkowski, S., Escherich, G. & Bergelt, C., 05.04.2022, In: BMJ OPEN. 12, 4, p. e055633

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Can Machine Learning Models Predict Asparaginase-associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia

    Nielsen, R. L., Wolthers, B. O., Helenius, M., Albertsen, B. K., Clemmensen, L., Nielsen, K., Kanerva, J., Niinimäki, R., Frandsen, T. L., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Aytan-Aktug, D., Liu, H-C., Möricke, A., Samarasinghe, S., van der Sluis, I. M., Stanulla, M., Tulstrup, M., Yadav, R., Zapotocka, E., Schmiegelow, K. & Gupta, R., 01.04.2022, In: J PEDIAT HEMATOL ONC. 44, 3, p. e628-e636

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Hematopoietic Stem Cell Transplantation with Mesenchymal Stromal Cells in Children with Metachromatic Leukodystrophy

    Cabanillas Stanchi, K. M., Böhringer, J., Strölin, M., Groeschel, S., Lenglinger, K., Treuner, C., Kehrer, C., Laugwitz, L., Bevot, A., Kaiser, N., Schumm, M., Lang, P., Handgretinger, R., Krägeloh-Mann, I., Müller, I. & Döring, M., 04.2022, In: STEM CELLS DEV. 31, 7-8, p. 163-175 13 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. Machine Learning Models Predict the Primary Sites of Head and Neck Squamous Cell Carcinoma Metastases Based on DNA Methylation

    Leitheiser, M., Capper, D., Seegerer, P., Lehmann, A., Schüller, U., Müller, K-R., Klauschen, F., Jurmeister, P. & Michael, B., 04.2022, In: J PATHOL. 256, 4, p. 378-387 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Mucha-Habermann disease: a pediatric case report and proposal of a risk score

    Blohm, M. E., Ebenebe, C. U., Rau, C., Escherich, C., Johannsen, J., Escherich, G., Driemeyer, J., Nagel, P. D., Kobbe, R., Lütgehetmann, M., Lennartz, M., Booken, N., Schneider, S. W. & Singer, D., 04.2022, In: INT J DERMATOL. 61, 4, p. 401-409 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  20. Spatial molecular profiling of a central nervous system low-grade diffusely infiltrative tumour with INI1 deficiency featuring a high-grade atypical teratoid/rhabdoid tumour component

    Dottermusch, M., Schumann, Y., Kordes, U., Hasselblatt, M. & Neumann, J. E., 04.2022, In: NEUROPATH APPL NEURO. 48, 3, p. e12777 e12777.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Quantification of Minimal Disease by Digital PCR in ALK-Positive Anaplastic Large Cell Lymphoma: A Step towards Risk Stratification in International Trials?

    Damm-Welk, C., Lovisa, F., Contarini, G., Lüdersen, J., Carraro, E., Knörr, F., Förster, J., Zimmermann, M., Sala, A., Vinti, L., Tondo, A., Pillon, M., Woessmann, W. & Mussolin, L., 27.03.2022, In: CANCERS. 14, 7, 1703.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Remission, treatment failure, and relapse in pediatric ALL: An international consensus of the Ponte-di-Legno Consortium

    Buchmann, S., Schrappe, M., Baruchel, A., Biondi, A., Borowitz, M. J., Campbell, M., Cario, G., Cazzaniga, G., Escherich, G., Harrison, C. J., Heyman, M., Hunger, S. P., Kiss, C., Liu, H-C., Locatelli, F., Loh, M. L., Manabe, A., Mann, G., Pieters, R., Pui, C-H., Rives, S., Schmiegelow, K., Silverman, L. B., Stary, J., Vora, A., Brown, P. A. & Ponte-di-Legno Consortium, 24.03.2022, In: BLOOD. 139, 12, p. 1785-1793 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  23. Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors

    Graf, M., Interlandi, M., Moreno, N., Holdhof, D., Göbel, C., Melcher, V., Mertins, J., Albert, T. K., Kastrati, D., Alfert, A., Holsten, T., de Faria, F., Meisterernst, M., Rossig, C., Warmuth-Metz, M., Nowak, J., Meyer Zu Hörste, G., Mayère, C., Nef, S., Johann, P., Frühwald, M. C., Dugas, M., Schüller, U. & Kerl, K., 22.03.2022, In: NAT COMMUN. 13, 1, 1544.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. The Reconstitution Dynamics of Cultivated Hematopoietic Stem Cells and Progenitors Is Independent of Age

    Gotzhein, F., Aranyossy, T., Thielecke, L., Sonntag, T., Thaden, V., Fehse, B., Müller, I., Glauche, I. & Cornils, K., 15.03.2022, In: INT J MOL SCI. 23, 6, 3160.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Increased replication stress and R-loop accumulation in EGFRvIII expressing glioblastoma present new therapeutic opportunities

    Struve, N., Hoffer, K., Weik, A-S., Riepen, B., Krug, L., Cetin, M. H., Burmester, J., Ott, L., Liebing, J., Gatzemeier, F., Müller-Goebel, J., Bußmann, L., Parplys, A. C., Unger, K., Mansour, W. Y., Schüller, U., Rieckmann, T., Petersen, C., Rothkamm, K., Short, S. C. & Kriegs, M., 12.03.2022, In: NEURO-ONCOL ADV. 4, 1, p. vdab180 vdab180.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Influence of Fetomaternal Microchimerism on Maternal NK Cell Reactivity against the Child's Leukemic Blasts

    Martin, L-M., Kruchen, A., Fehse, B. & Müller, I., 04.03.2022, In: BIOMEDICINES. 10, 3, 603.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. A new amplicon-based gene panel for next generation sequencing characterization of meningiomas

    Mawrin, C., Koch, R., Waldt, N., Sandalcioglu, I. E., Braunsdorf, W. K., Warnke, J-P., Goehre, F., Meisel, H-J., Ewald, C., Neyazi, S., Schüller, U. & Kirches, E., 03.2022, In: BRAIN PATHOL. 32, 2, e13046.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  28. Clinical and molecular characterization of isolated M1 disease in pediatric medulloblastoma: experience from the German HIT-MED studies

    Obrecht, D., Mynarek, M., Hagel, C., Kwiecien, R., Spohn, M., Bockmayr, M., Bison, B., Pfister, S. M., Jones, D. T. W., Sturm, D., von Deimling, A., Sahm, F., von Hoff, K., Juhnke, B-O., Benesch, M., Gerber, N. U., Friedrich, C., von Bueren, A. O., Kortmann, R-D., Schwarz, R., Pietsch, T., Fleischhack, G., Schüller, U. & Rutkowski, S., 03.2022, In: J NEURO-ONCOL. 157, 1, p. 37-48 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma

    Hohm, A., Karremann, M., Gielen, G. H., Pietsch, T., Warmuth-Metz, M., Vandergrift, L. A., Bison, B., Stock, A., Hoffmann, M., Pham, M., Kramm, C. M. & Nowak, J., 03.2022, In: CLIN NEURORADIOL. 32, 1, p. 249-258 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Refining M1 stage in medulloblastoma: criteria for cerebrospinal fluid cytology and implications for improved risk stratification from the HIT-2000 trial

    Hagel, C., Sloman, V., Mynarek, M., Petrasch, K., Obrecht, D., Kühl, J., Deinlein, F., Schmid, R., von Bueren, A. O., Friedrich, C., Juhnke, B. O., Gerber, N. U., Kwiecien, R., Girschick, H., Höller, A., Zapf, A., von Hoff, K. & Rutkowski, S., 03.2022, In: EUR J CANCER. 164, p. 30-38

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Types of deviation and review criteria in pretreatment central quality control of tumor bed boost in medulloblastoma-an analysis of the German Radiotherapy Quality Control Panel in the SIOP PNET5 MB trial

    Dietzsch, S., Braesigk, A., Seidel, C., Remmele, J., Kitzing, R., Schlender, T., Mynarek, M., Geismar, D., Jablonska, K., Schwarz, R., Pazos, M., Weber, D. C., Frick, S., Gurtner, K., Matuschek, C., Harrabi, S. B., Glück, A., Lewitzki, V., Dieckmann, K., Benesch, M., Gerber, N. U., Obrecht, D., Rutkowski, S., Timmermann, B. & Kortmann, R-D., 03.2022, In: STRAHLENTHER ONKOL. 198, 3, p. 282-290 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Multimodal Treatment of Nasopharyngeal Carcinoma in Children, Adolescents and Young Adults-Extended Follow-Up of the NPC-2003-GPOH Study Cohort and Patients of the Interim Cohort

    Römer, T., Franzen, S., Kravets, H., Farrag, A., Makowska, A., Christiansen, H., Eble, M. J., Timmermann, B., Staatz, G., Mottaghy, F. M., Bührlen, M., Hagenah, U., Puzik, A., Driever, P. H., Greiner, J., Jorch, N., Tippelt, S., Schneider, D. T., Kropshofer, G., Overbeck, T. R., Christiansen, H., Brozou, T., Escherich, G., Becker, M., Friesenbichler, W., Feuchtinger, T., Puppe, W., Heussen, N., Hilgers, R. D. & Kontny, U., 28.02.2022, In: CANCERS. 14, 5, 1261.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Akute lymphoblastische Leukämie

    Escherich, G., Möricke, A., Horstmann, M. & Schrappe, M., 15.02.2022, Kompendium Internistische Onkologie: Standards in Diagnostik und Therapie. Schmoll, H-J. (ed.). 5 ed. Berlin, Heidelberg: Springer, 11 p.

    Research output: SCORING: Contribution to book/anthology › Chapter › Research › peer-review

  34. NET Release of Long-Term Surviving Neutrophils

    Kolman, J. P., Pagerols Raluy, L., Müller, I., Nikolaev, V., Trochimiuk, M., Appl, B., Wadehn, H., Dücker, C., Stoll, F., Boettcher, M., Reinshagen, K. & Trah, J., 15.02.2022, In: FRONT IMMUNOL. 13, p. 815412 815412.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Primary central nervous system sarcoma with DICER1 mutation-treatment results of a novel molecular entity in pediatric Peruvian patients

    Diaz Coronado, R. Y., Mynarek, M., Koelsche, C., Mora Alferez, P., Casavilca Zambrano, S., Wachtel Aptowitzer, A., Sahm, F., von Deimling, A., Schüller, U., Spohn, M., Sturm, D., Pfister, S. M., Morales La Madrid, A., Sernaque Quintana, R., Sarria Bardales, G., Negreiros Chinchihuara, T., Ojeda Medina, L., Garcia-Corrochano Medina, P., Campos Sanchez, D. A., Ponce Farfan, J., Rutkowski, S. & Garcia Leon, J. L., 15.02.2022, In: CANCER-AM CANCER SOC. 128, 4, p. 697-707 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma

    Lechner, M., Takahashi, Y., Turri-Zanoni, M., Liu, J., Counsell, N., Hermsen, M., Kaur, R. P., Zhao, T., Ramanathan, M., Schartinger, V. H., Emanuel, O., Helman, S., Varghese, J., Dudas, J., Riechelmann, H., Sprung, S., Haybaeck, J., Howard, D., Engel, N. W., Stewart, S., Brooks, L., Pickles, J. C., Jacques, T. S., Fenton, T. R., Williams, L., Vaz, F. M., O'Flynn, P., Stimpson, P., Wang, S., Hannan, S. A., Unadkat, S., Hughes, J., Dwivedi, R., Forde, C. T., Randhawa, P., Gane, S., Joseph, J., Andrews, P. J., Royle, G., Franchi, A., Maragliano, R., Battocchio, S., Bewicke-Copley, H., Pipinikas, C., Webster, A., Thirlwell, C., Ho, D., Teschendorff, A., Zhu, T., Steele, C. D., Pillay, N., Vanhaesebroeck, B., Mohyeldin, A., Fernandez-Miranda, J., Park, K. W., Le, Q-T., West, R. B., Saade, R., Manes, R. P., Omay, S. B., Vining, E. M., Judson, B. L., Yarbrough, W. G., Sansovini, M., Silvia, N., Grassi, I., Bongiovanni, A., Capper, D., Schüller, U., Thavaraj, S., Sandison, A., Surda, P., Hopkins, C., Ferrari, M., Mattavelli, D., Rampinelli, V., Facchetti, F., Nicolai, P., Bossi, P., Henriquez, O. A., Magliocca, K., Solares, C. A., Wise, S. K., Llorente, J. L., Patel, Z. M., Nayak, J. V., Hwang, P. H., Lacy, P. D., Woods, R., O'Neill, J. P., Jay, A., Carnell, D., Forster, M. D., Ishii, M., London, N. R., Bell, D. M., Gallia, G. L., Castelnuovo, P., Severi, S., Lund, V. J. & Hanna, E. Y., 02.2022, In: EUR J CANCER. 162, p. 221-236 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Final results of the Choroid Plexus Tumor study CPT-SIOP-2000

    Wolff, J. E., Van Gool, S. W., Kutluk, T., Diez, B., Kebudi, R., Timmermann, B., Garami, M., Sterba, J., Fuller, G. N., Bison, B. & Kordes, U. R., 02.2022, In: J NEURO-ONCOL. 156, 3, p. 599-613 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Gain-of-function variant p.Pro2555Arg of von Willebrand factor increases aggregate size through altering stem dynamics

    Huck, V., Chen, P-C., Xu, E-R., Tischer, A., Klemm, U., Aponte-Santamaría, C., Mess, C., Obser, T., Kutzki, F., König, G., Denis, C., Gräter, F., Wilmanns, M., Auton, M., Schneider, S. W., Schneppenheim, R., Hennig, J. & Brehm, M. A., 02.2022, In: THROMB HAEMOSTASIS. 122, 2, p. 226-239 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Hypersensitivity to Pegylated E.colia sparaginase as first-line treatment in contemporary paediatric acute lymphoblastic leukaemia protocols: a meta-analysis of the Ponte di Legno Toxicity working group

    Brigitha, L. J., Fiocco, M., Pieters, R., Albertsen, B. K., Escherich, G., Lopez-Lopez, E., Mondelaers, V., Vora, A., Vrooman, L., Schmiegelow, K., van der Sluis, I. M. & Ponte di Legno toxicity working group, 02.2022, In: EUR J CANCER. 162, p. 65-75 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Long-term survival of an adolescent glioblastoma patient under treatment with vinblastine and valproic acid illustrates importance of methylation profiling

    Kresbach, C., Bronsema, A., Guerreiro, H., Rutkowski, S., Schüller, U. & Winkler, B., 02.2022, In: CHILD NERV SYST. 38, 2, p. 479-483 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Maternal versus paternal living kidney transplant donation is associated with lower rejection in young pediatric recipients: A Collaborative Transplant Study report

    Engels, G., Döhler, B., Tönshoff, B., Oh, J., Kruchen, A., Müller, I. & Süsal, C., 02.2022, In: PEDIATR TRANSPLANT. 26, 1, e14154.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Local and Systemic Therapy of Recurrent Medulloblastomas in Children and Adolescents: Results of the P-HIT-REZ 2005 Study

    Gaab, C., Adolph, J. E., Tippelt, S., Mikasch, R., Obrecht, D., Mynarek, M., Rutkowski, S., Pfister, S. M., Milde, T., Witt, O., Bison, B., Warmuth-Metz, M., Kortmann, R-D., Dietzsch, S., Pietsch, T., Timmermann, B., Sträter, R., Bode, U., Faldum, A., Kwiecien, R. & Fleischhack, G., 18.01.2022, In: CANCERS. 14, 3, 471.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial

    Bailey, S., André, N., Gandola, L., Massimino, M., Rutkowski, S. & Clifford, S. C., 13.01.2022, In: CANCERS. 14, 2, 374.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  44. Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and high-dose chemotherapy within the prospective P-HIT trial

    Juhnke, B-O., Gessi, M., Gerber, N. U., Friedrich, C., Mynarek, M., von Bueren, A. O., Haberler, C., Schüller, U., Kortmann, R-D., Timmermann, B., Bison, B., Warmuth-Metz, M., Kwiecien, R., Pfister, S. M., Spix, C., Pietsch, T., Kool, M., Rutkowski, S. & von Hoff, K., 05.01.2022, In: NEURO-ONCOLOGY. 24, 1, p. 127-137 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

    Das, A., Sudhaman, S., Morgenstern, D., Coblentz, A., Chung, J., Stone, S. C., Alsafwani, N., Liu, Z. A., Karsaneh, O. A. A., Soleimani, S., Ladany, H., Chen, D., Zatzman, M., Cabric, V., Nobre, L., Bianchi, V., Edwards, M., Sambira Nahum, L. C., Ercan, A. B., Nabbi, A., Constantini, S., Dvir, R., Yalon-Oren, M., Campino, G. A., Caspi, S., Larouche, V., Reddy, A., Osborn, M., Mason, G., Lindhorst, S., Bronsema, A., Magimairajan, V., Opocher, E., De Mola, R. L., Sabel, M., Frojd, C., Sumerauer, D., Samuel, D., Cole, K., Chiaravalli, S., Massimino, M., Tomboc, P., Ziegler, D. S., George, B., Van Damme, A., Hijiya, N., Gass, D., McGee, R. B., Mordechai, O., Bowers, D. C., Laetsch, T. W., Lossos, A., Blumenthal, D. T., Sarosiek, T., Yen, L. Y., Knipstein, J., Bendel, A., Hoffman, L. M., Luna-Fineman, S., Zimmermann, S., Scheers, I., Nichols, K. E., Zapotocky, M., Hansford, J. R., Maris, J. M., Dirks, P., Taylor, M. D., Kulkarni, A. V., Shroff, M., Tsang, D. S., Villani, A., Xu, W., Aronson, M., Durno, C., Shlien, A., Malkin, D., Getz, G., Maruvka, Y. E., Ohashi, P. S., Hawkins, C., Pugh, T. J., Bouffet, E. & Tabori, U., 01.2022, In: NAT MED. 28, 1, p. 125-135 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. Reduced-Intensity/Reduced-Toxicity Conditioning Approaches Are Tolerated in XIAP Deficiency but Patients Fare Poorly with Acute GVHD

    Arnold, D. E., Nofal, R., Wakefield, C., Lehmberg, K., Wustrau, K., Albert, M. H., Morris, E. C., Heimall, J. R., Bunin, N. J., Kumar, A., Jordan, M. B., Cole, T., Choo, S., Brettig, T., Speckmann, C., Ehl, S., Salamonowicz, M., Wahlstrom, J., Rao, K., Booth, C., Worth, A. & Marsh, R. A., 01.2022, In: J CLIN IMMUNOL. 42, 1, p. 36-45 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity

    Groß, M., Speckmann, C., May, A., Gajardo-Carrasco, T., Wustrau, K., Maier, S. L., Panning, M., Huzly, D., Agaimy, A., Bryceson, Y. T., Choo, S., Chow, C. W., Dückers, G., Fasth, A., Fraitag, S., Gräwe, K., Haxelmans, S., Holzinger, D., Hudowenz, O., Hübschen, J. M., Khurana, C., Kienle, K., Klifa, R., Korn, K., Kutzner, H., Lämmermann, T., Ledig, S., Lipsker, D., Meeths, M., Naumann-Bartsch, N., Rascon, J., Schänzer, A., Seidl, M., Tesi, B., Vauloup-Fellous, C., Vollmer-Kary, B., Warnatz, K., Wehr, C., Neven, B., Vargas, P., Sepulveda, F. E., Lehmberg, K., Schmitt-Graeff, A. & Ehl, S., 01.2022, In: J ALLERGY CLIN IMMUN. 149, 1, p. 388-399.e4

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. 2021

  49. Relapsed Medulloblastoma in Pre-Irradiated Patients: Current Practice for Diagnostics and Treatment

    Hill, R. M., Plasschaert, S. L. A., Timmermann, B., Dufour, C., Aquilina, K., Avula, S., Donovan, L., Lequin, M., Pietsch, T., Thomale, U., Tippelt, S., Wesseling, P., Rutkowski, S., Clifford, S. C., Pfister, S. M., Bailey, S. & Fleischhack, G., 28.12.2021, In: CANCERS. 14, 1, 126.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  50. Ex vivo testis explant culture of human testicular tissue

    Aden, N. L., Soave, A., Kordes, U., Bleeke, M., Salzbrunn, A. & von Kopylow, K., 05.12.2021, In: J Reprodmed Endokrinol. 2020, 17 (Supplementum 1), 39-40

    Research output: SCORING: Contribution to journal › Conference abstract in journal › Research

  51. SIOP PNET5 MB Trial: History and Concept of a Molecularly Stratified Clinical Trial of Risk-Adapted Therapies for Standard-Risk Medulloblastoma

    Mynarek, M., Milde, T., Padovani, L., Janssens, G. O., Kwiecien, R., Mosseri, V., Clifford, S. C., Doz, F. & Rutkowski, S., 02.12.2021, In: CANCERS. 13, 23, 1677.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  52. Dose-adjusted EPOCH-rituximab or intensified B-NHL therapy for pediatric primary mediastinal large B-cell lymphoma

    Knörr, F., Zimmermann, M., Attarbaschi, A., Kabickova, E., Maecker-Kolhoff, B., Ruf, S., Kühnle, I., Ebinger, M., Garthe, A-K., Simonitsch-Klupp, I., Oschlies, I., Klapper, W., Burkhardt, B. & Wößmann, W., 01.12.2021, In: HAEMATOLOGICA. 106, 12, p. 3232-3235 4 p.

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

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