Research ExplorerScientific StaffWalter Fiedler Publications

Prof.Dr. ID: 50717

Walter Fiedler

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Publications

  1. 2012

  2. Critical imbalance of TNF-α and soluble TNF receptor 1 in a patient with macrophage activation syndrome: potential implications for diagnostics and treatment.

    Flammiger, A., Fiedler, W., Bacher, U., Bokemeyer, C., Schneider, M. & Binder, M., 2012, In: ACTA HAEMATOL-BASEL. 128, 2, p. 69-72 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. The metabolite 3-hydroxiglutaric acid effectively reduces glioblastoma growth in vivo by affecting the structural integrity of tumor vasculature.

    Oliveira-Ferrer, L., Wellbrock, J., Balabanov, M., Klockow, M., Hauschild, J., Bokemeyer, C., Fiedler, W., Ergun, S. & Schuch, G., 2012, In: CANCER LETT. 326, 2, p. 161-167 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. 2011

  5. Expression of TGF-β receptor ALK-5 has a negative impact on outcome of patients with acute myeloid leukemia

    Otten, J., Schmitz, L., Vettorazzi, E., Schultze, A., Marx, A. H., Simon, R., Krauter, J., Loges, S., Sauter, G., Bokemeyer, C. & Fiedler, W., 01.02.2011, In: LEUKEMIA. 25, 2, p. 375-9 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Addition of AEG35156 XIAP antisense oligonucleotide in reinduction chemotherapy does not improve remission rates in patients with primary refractory acute myeloid leukemia in a randomized phase II study.

    Schimmer, A. D., Herr, W., Hänel, M., Borthakur, G., Frankel, A., Horst, H-A., Martin, S., Kassis, J., Desjardins, P., Seiter, K., Fiedler, W., Noppeney, R., Giagounidis, A., Jacob, C., Jolivet, J., Tallman, M. S. & Koschmieder, S., 2011, In: CL LYMPH MYELOM LEUK. 11, 5, p. 433-438 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. A phase I study of recombinant human interleukin-21 (rIL-21) in combination with sunitinib in patients with metastatic renal cell carcinoma (RCC).

    Grünwald, V., Desar, I. M. E., Haanen, J., Fiedler, W., Mouritzen, U., Olsen, M. W. B., Herpen, V. & Carla, M. L., 2011, In: ACTA ONCOL. 50, 1, p. 121-126 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Clinical experience with antiangiogenic therapy in leukemia.

    Wellbrock, J. & Fiedler, W., 2011, In: CURR CANCER DRUG TAR. 11, 9, p. 1053-1068 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Clinical importance and potential use of small molecule inhibitors of focal adhesion kinase.

    Schultze, A. & Fiedler, W., 2011, In: ANTI-CANCER AGENT ME. 11, 7, p. 593-599 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Factors affecting the unexpected failure of DCE-MRI to determine the optimal biological dose of the vascular targeting agent NGR-hTNF in solid cancer patients.

    Desar, U., Ingrid, M. E., Herpen, V., Carla, M. L., Asten, V., Jack, J. A., Fiedler, W., Walter, U., Marreaud, U., Sandrine, U., Timmer-Bonte, U., Johanna, N. H., Ter, V., Edwin, G. W., Lambiase, U., Antonio, U., Bordignon, U., Claudio, U., Heerschap, U., Arend, U., Laarhoven, V. & Hanneke, W. M., 2011, In: EUR J RADIOL. 80, 3, p. 655-661 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia.

    Thol, F., Damm, F., Lüdeking, A., Winschel, C., Wagner, K., Morgan, M., Yun, H., Göhring, G., Schlegelberger, B., Hoelzer, D., Lübbert, M., Kanz, L., Fiedler, W., Kirchner, H., Heil, G., Krauter, J., Ganser, A. & Heuser, M., 2011, In: J CLIN ONCOL. 29, 21, p. 2889-2896 21.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Integrative prognostic risk score in acute myeloid leukemia with normal karyotype.

    Damm, F., Heuser, M., Morgan, M., Wagner, K., Görlich, K., Grosshennig, A., Hamwi, I., Thol, F., Surdziel, E., Fiedler, W., Lübbert, M., Kanz, L., Reuter, C., Heil, G., Delwel, R., Löwenberg, B., Valk, P. J. M., Krauter, J. & Ganser, A., 2011, In: BLOOD. 117, 17, p. 4561-4568 17.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Phase I trial of SU14813 in patients with advanced solid malignancies.

    Fiedler, W., Giaccone, G., Lasch, P., van der Horst, I., Brega, N., Courtney, R., Abbattista, A., Shalinsky, D. R., Bokemeyer, C. & Boven, E., 2011, In: ANN ONCOL. 22, 1, p. 195-201 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Plerixafor is effective and safe for stem cell mobilization in heavily pretreated germ cell tumor patients.

    Kobold, S., Isernhagen, J., Hübel, K., Kilic, N., Bogner, C., Frickhofen, N., Bokemeyer, C. & Fiedler, W., 2011, In: BONE MARROW TRANSPL. 46, 8, p. 1053-1056 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. Primary tumor dependent inhibition of tumor growth, Angio-Genesis, and perfusion of secondary breast cancer in bone.

    Schäfer, C., Schröder, M., Fuhrhop, I., Viezens, L., Wellbrock, J., Fiedler, W., Rüther, W. & Hansen-Algenstaedt, N., 2011, In: J ORTHOP RES. 29, 8, p. 1251-1258 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  16. Prognostic importance of histone methyltransferase MLL5 expression in acute myeloid leukemia.

    Damm, F., Oberacker, T., Thol, F., Surdziel, E., Wagner, K., Chaturvedi, A., Morgan, M., Bomm, K., Göhring, G., Lübbert, M., Kanz, L., Fiedler, W., Schlegelberger, B., Heil, G., Schlenk, R. F., Döhner, K., Döhner, H., Krauter, J., Ganser, A. & Heuser, M., 2011, In: J CLIN ONCOL. 29, 6, p. 682-689 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies.

    Hu-Lowe, D. D., Chen, E., Zhang, L., Watson, K. D., Mancuso, P., Lappin, P., Wickman, G., Chen, J. H., Wang, J., Jiang, X., Amundson, K., Simon, R., Erbersdobler, A., Bergqvist, S., Feng, Z., Swanson, T. A., Simmons, B. H., Lippincott, J., Casperson, G. F., Levin, W. J., Stampino, C. G., Shalinsky, D. R., Ferrara, K. W., Fiedler, W. & Bertolini, F., 2011, In: CANCER RES. 71, 4, p. 1362-1373 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  18. 2010

  19. [28-year old female patient with respiratory insufficiency, elevated liver enzymes, pancytopenia and fever].

    Wolschke, C., Fiedler, W., Habermann, C., Janka-Schaub, G. & Kluge, S., 2010, In: INTERNIST. 51, 11, p. 1434-1438 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Heterogenous high-level HER-2 amplification in a small subset of colorectal cancers.

    Marx, A., Burandt, E. C., Choschzick, M., Simon, R., Yekebas, E. F., Kaifi, J., Mirlacher, M., Atanackovic, D., Bokemeyer, C., Fiedler, W., Terracciano, L., Sauter, G. & Izbicki, J. R., 2010, In: HUM PATHOL. 41, 11, p. 1577-1585 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Homogeneous EGFR amplification defines a subset of aggressive Barrett's adenocarcinomas with poor prognosis.

    Marx, A., Zielinski, M., Kowitz, C-M., Dancau, A. M., Thieltges, S., Simon, R., Choschzick, M., Yekebas, E. F., Kaifi, J., Mirlacher, M., Atanackovic, D., Brümmendorf, T., Fiedler, W., Bokemeyer, C., Izbicki, J. R. & Sauter, G., 2010, In: HISTOPATHOLOGY. 57, 3, p. 418-426 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor.

    Wagner, K., Damm, F., Göhring, G., Görlich, K., Heuser, M., Schäfer, I., Ottmann, O., Lübbert, M., Heit, W., Kanz, L., Schlimok, G., Raghavachar, A. A., Fiedler, W., Kirchner, H. H., Brugger, W., Zucknick, M., Schlegelberger, B., Heil, G., Ganser, A. & Krauter, J., 2010, In: J CLIN ONCOL. 28, 14, p. 2356-2364 14.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Isolated limb perfusion with melphalan for the treatment of intractable primary cutaneous diffuse large B-cell lymphoma leg type.

    Kobold, S., Kilic, N., Luetkens, T., Bokemeyer, C. & Fiedler, W., 2010, In: ACTA HAEMATOL-BASEL. 123, 3, p. 179-181 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Microcirculation of secondary bone tumors in vivo: the impact of minor surgery at a distal site.

    Schäfer, C., Fuhrhop, I., Schröder, M., Viezens, L., Wellbrock, J., Fiedler, W., Rüther, W. & Hansen-Algenstaedt, N., 2010, In: J ORTHOP RES. 28, 11, p. 1515-1521 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Phase I clinical and magnetic resonance imaging study of the vascular agent NGR-hTNF in patients with advanced cancers (European Organization for Research and Treatment of Cancer Study 16041).

    Laarhoven, V., Fiedler, W., Fiedler, W., Desar, I. M. E., Asten, V., Jack, J. A., Marréaud, S., Lacombe, D., Govaerts, A-S., Bogaerts, J., Lasch, P., Timmer-Bonte, J. N. H., Lambiase, A., Bordignon, C., Punt, C. J. A., Heerschap, A., Herpen, V. & Carla, M. L., 2010, In: CLIN CANCER RES. 16, 4, p. 1315-1323 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia.

    Thol, F., Damm, F., Wagner, K., Göhring, G., Schlegelberger, B., Hoelzer, D., Lübbert, M., Heit, W., Kanz, L., Schlimok, G., Raghavachar, A., Fiedler, W., Kirchner, H., Heil, G., Heuser, M., Krauter, J. & Ganser, A., 2010, In: BLOOD. 116, 4, p. 614-616 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Tgf-Beta superfamily receptors-targets for antiangiogenic therapy?

    Wellbrock, J., Bokemeyer, C. & Fiedler, W., 2010, In: J Oncol. 2010, p. 317068

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer.

    Schultze, A. & Fiedler, W., 2010, In: EXPERT OPIN INV DRUG. 19, 6, p. 777-788 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. 2009

  30. An open-label, Phase I study of cediranib (RECENTIN) in patients with acute myeloid leukemia.

    Fiedler, W., Mesters, R., Heuser, M., Ehninger, G., Berdel, W. E., Zirrgiebel, U., Robertson, J. D., Puchalski, T. A., Collins, B., Jürgensmeier, J. M. & Serve, H., 2009, In: LEUKEMIA RES.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Characterisation of extramedullary relapse in patients with chronic myeloid leukemia in advanced disease after allogeneic stem cell transplantation.

    Ocheni, S., Iwanski, G., Schafhausen, P., Zander, A. R., Ayuketang Ayuk, F., Klyuchnikov, E., Zabelina, T., Fiedler, W., Schnittger, S., Hochhaus, A., Brümmendorf, T., Kröger, N. & Bacher, U., 2009, In: LEUKEMIA LYMPHOMA. 50, 4, p. 551-558 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Effective strategies for management of hypertension after vascular endothelial growth factor signaling inhibition therapy: results from a phase II randomized, factorial, double-blind study of Cediranib in patients with advanced solid tumors.

    Langenberg, M. H. G., Herpen, V., Carla, M. L., Johann, D. B., Schellens, J. H. M., Unger, C., Hoekman, K., Fiedler, W., Fiedler, W., Drevs, J., Florence, L. M., Fielding, A., Robertson, J. & Voest, E. E., 2009, In: J CLIN ONCOL. 27, 36, p. 6152-6159 36.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. Primary NK/T cell lymphoma nasal type of the stomach with skin involvement: a case report

    Kobold, S., Merz, H., Tiemann, M., Mahuad, C., Bokemeyer, C., Koop, I. & Fiedler, W., 2009, In: RARE TUMORS. 1, 2, p. 173-175 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Reduced proliferation of CD34(+) cells from patients with acute myeloid leukemia after gene transfer of INPP5D.

    Metzner, A., Precht, C., Fehse, B., Fiedler, W., Stocking, C., Günther, A., Mayr, G. W. & Jücker, M., 2009, In: GENE THER. 16, 4, p. 570-573 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. Single Nucleotide Polymorphism in the Mutational Hotspot of WT1 Predicts a Favorable Outcome in Patients With Cytogenetically Normal Acute Myeloid Leukemia.

    Damm, F., Heuser, M., Morgan, M., Yun, H., Großhennig, A., Göhring, G., Schlegelberger, B., Döhner, K., Ottmann, O., Lübbert, M., Heit, W., Kanz, L., Schlimok, G., Raghavachar, A., Fiedler, W., Kirchner, H., Döhner, H., Heil, G., Ganser, A. & Krauter, J., 2009, In: J CLIN ONCOL.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis.

    Schultze, A., Decker, S., Wellbrock, J., Horst, A., Vohwinkel, G., Schuch, G., Bokemeyer, C., Loges, S. & Fiedler, W., 2009, In: INVEST NEW DRUG.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. 2008

  38. Blood outgrowth endothelial cells from chronic myeloid leukaemia patients are BCR/ABL1 negative.

    Wellbrock, J., Schultze, A., Schafhausen, P., Otterstetter, S., Dierlamm, J., Bokemeyer, C., Brümmendorf, T., Fiedler, W. & Loges, S., 2008, In: BRIT J HAEMATOL. 142, 1, p. 115-118 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. Cilengitide induces cellular detachment and apoptosis in endothelial and glioma cells mediated by inhibition of FAK/src/AKT pathway.

    Oliveira-Ferrer, L., Hauschild, J., Fiedler, W., Bokemeyer, C., Nippgen, J., Celik, I. & Schuch, G., 2008, In: J EXP CLIN CANC RES. 27, p. 86

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. Esophageal squamous cell carcinoma presenting with extensive skin lesions: a case report

    Iwanski, G., Block, A., von Amsberg, G., Münch, J., Claus, S., Fiedler, W. & Bokemeyer, C., 2008, In: J MED CASE REP. 2, p. 115

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Impact of genetic abnormalities on survival after allogeneic hematopoietic stem cell transplantation in multiple myeloma.

    Schilling, G., Hansen, T., Shimoni, A., Zabelina, T., Pérez-Simón, J-A., Simon-Perez, J-A., Gutierrez, N. C., Fiedler, W., Liebisch, P., Schwerdtfeger, R., Bornhäuser, M., Otterstetter, S., Murga-Penas, E-M., Dierlamm, J., Ayuketang Ayuk, F., Atanackovic, D., Bacher, U., Bokemeyer, C., Zander, A. R., San Miguel, J., Miguel, J. S., Nagler, A. & Kröger, N., 2008, In: LEUKEMIA. 22, 6, p. 1250-1255 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. PHA-680626 exhibits anti-proliferative and pro-apoptotic activity on Imatinib-resistant chronic myeloid leukemia cell lines and primary CD34+ cells by inhibition of both Bcr-Abl tyrosine kinase and Aurora kinases.

    Gontarewicz, A., Balabanov, S., von Amsberg, G., Panse, J., Schafhausen, P., Bokemeyer, C., Fiedler, W., Moll, J. & Brümmendorf, T., 2008, In: LEUKEMIA RES. 32, 12, p. 1857-1865 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Prognostic implication of expression of Angiopoietin-2 in acute myeloid leukemia.

    Fiedler, W., Schuch, G. & Loges, S., 2008, In: LEUKEMIA RES. 32, 6, p. 843-844 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I.

    Gontarewicz, A., Balabanov, S., von Amsberg, G., Colombo, R., Graziano, A., Pesenti, E., Benten, D., Bokemeyer, C., Fiedler, W., Moll, J. & Brümmendorf, T., 2008, In: BLOOD. 111, 8, p. 4355-4364 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Time-course-dependent microvascular alterations in a model of myeloid leukemia in vivo.

    Schäfer, C., Krause, M., Fuhrhop, I., Schröder, M., Algenstaedt, P., Fiedler, W., Rüther, W. & Hansen-Algenstaedt, N., 2008, In: LEUKEMIA. 22, 1, p. 59-65 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. 2007

  47. CFU-EC: how they were originally defined.

    Gehling, U., Ergün, S. & Fiedler, W., 2007, In: BLOOD. 110, 3, p. 1073 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. Cilengitide inhibits proliferation and differentiation of human endothelial progenitor cells in vitro.

    Loges, S., Butzal, M., Wellbrock, J., Schweizer, M., Fischer, U., Bokemeyer, C., Hossfeld, D. K., Schuch, G. & Fiedler, W., 2007, In: BIOCHEM BIOPH RES CO. 357, 4, p. 1016-1020 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. Determination of microvessel density by quantitative real-time PCR in esophageal cancer: correlation with histologic methods, angiogenic growth factor expression, and lymph node metastasis.

    Loges, S., Clausen, H., Reichelt, U., Bubenheim, M., Erbersdobler, A., Schurr, P., Yekebas, E. F., Schuch, G., Izbicki, J. R., Pantel, K., Bokemeyer, C. & Fiedler, W., 2007, In: CLIN CANCER RES. 13, 1, p. 76-80 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. [Development of angiogenesis inhibitory combination therapies for treatment of renal cell carcinoma]

    Bartsch, G., Eggert, K., Soker, S., Fiedler, W., Laack, E., Volkmer, B. G., Gschwend, J., Bokemeyer, C., Hautmann, R. & Schuch, G., 2007, In: UROLOGE. 46, 9, p. 1289-1290 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Managing side effects of angiogenesis inhibitors in renal cell carcinoma.

    Grünwald, V., Heinzer, H. & Fiedler, W., 2007, In: ONKOLOGIE. 30, 10, p. 519-524 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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