PD Dr. med. ID: 43961

Tim Ullrich Magnus

graph of relations

Publications

  1. Adult glial precursor proliferation in mutant SOD1G93A mice.

    Magnus, T., Carmen, J., Deleon, J., Xue, H., Pardo, A. C., Lepore, A. C., Mattson, M. P., Rao, M. S. & Maragakis, N. J., 2008, In: GLIA. 56, 2, p. 200-208 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  2. An atypical role for the myeloid receptor Mincle in central nervous system injury

    Arumugam, T. V., Manzanero, S., Furtado, M., Biggins, P. J., Hsieh, Y-H., Gelderblom, M., MacDonald, K. P., Salimova, E., Li, Y-I., Korn, O., Dewar, D., Macrae, I. M., Ashman, R. B., Tang, S-C., Rosenthal, N. A., Ruitenberg, M. J., Magnus, T. & Wells, C. A., 06.2017, In: J CEREBR BLOOD F MET. 37, 6, p. 2098-2111

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Antikörper-assoziierte autoimmune Enzephalopathien

    Friese, M., Kastrup, O. & Magnus, T. U., 2017, Therapie und Verlauf neurologischer Erkrankungen: 7., erweiterte und überarbeitete Auflage. Diener, H-C., Dieterich, M. & Gerloff, C. (eds.). 7 ed. Stuttgart: Kohlhammer, p. 770-780 11 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  4. A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice

    Er-Lukowiak, M., Duan, Y., Rassendren, F., Ulmann, L., Nicke, A., Ufer, F., Friese, M. A., Koch-Nolte, F., Magnus, T. & Rissiek, B., 18.12.2020, In: ISCIENCE. 23, 12, p. 101870

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. A preclinical randomized controlled multi-centre trial of anti-interleukin-17A treatment for acute ischaemic stroke

    Gelderblom, M., Koch, S., Strecker, J-K., Jørgensen, C., Garcia-Bonilla, L., Ludewig, P., Schädlich, I. S., Piepke, M., Degenhardt, K., Bernreuther, C., Pinnschmidt, H., Arumugam, T. V., Thomalla, G., Faber, C., Sedlacik, J., Gerloff, C., Minnerup, J., Clausen, B. H., Anrather, J. & Magnus, T., 23.03.2023, In: BRAIN COMMUN. 5, 2, p. fcad090

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Astrocytes and Microglia Are Resistant to NAD+-Mediated Cell Death Along the ARTC2/P2X7 Axis

    Rissiek, B., Stabernack, J., Cordes, M., Duan, Y., Behr, S., Menzel, S., Magnus, T. & Koch-Nolte, F., 01.2020, In: FRONT MOL NEUROSCI. 12, p. 330

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Astrocytes are less efficient in the removal of apoptotic lymphocytes than microglia cells: implications for the role of glial cells in the inflamed central nervous system

    Magnus, T., Chan, A., Linker, R. A., Toyka, K. V. & Gold, R., 09.2002, In: J NEUROPATH EXP NEUR. 61, 9, p. 760-6 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Autoimmune modulation of astrocyte-mediated homeostasis.

    Korn, T., Rao, M. & Magnus, T., 2007, In: NEUROMOL MED. 9, 1, p. 1-16 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. [Autoimmune synaptic encephalopathies].

    Friese, M. A. & Magnus, T., 2011, In: NERVENARZT. 82, 10, p. 1239-1249 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Autoimmunity After Ischemic Stroke and Brain Injury

    Javidi, E. & Magnus, T. U., 02.04.2019, In: FRONT IMMUNOL.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  11. Blockade of P2X7 receptors or pannexin-1 channels similarly attenuates postischemic damage

    Cisneros-Mejorado, A., Gottlieb, M., Cavaliere, F., Magnus, T., Nolte, F., Scemes, E., Pérez-Samartín, A. & Matute, C., 05.2015, In: J CEREBR BLOOD F MET. 35, 5, p. 843-50 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Blocking of α4 Integrin Does Not Protect From Acute Ischemic Stroke in Mice

    Langhauser, F., Kraft, P., Göb, E., Leinweber, J., Schuhmann, M. K., Lorenz, K., Gelderblom, M., Bittner, S., Meuth, S. G., Wiendl, H., Magnus, T. & Kleinschnitz, C., 2014, In: STROKE. 45, 6, p. 1799-+

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions

    Wilmes, M., Pinto Espinoza, C., Ludewig, P., Stabernack, J., Liesz, A., Nicke, A., Gelderblom, M., Gerloff, C., Falzoni, S., Tolosa, E., Di Virgilio, F., Rissiek, B., Plesnilla, N., Koch-Nolte, F. & Magnus, T., 12.10.2022, In: J NEUROINFLAMM. 19, 1, 256.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Blood neurofilament light chain in Parkinson's disease

    Buhmann, C., Magnus, T. & Choe, C-U., 06.2023, In: J NEURAL TRANSM. 130, 6, p. 755-762 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  15. Brain-Derived Extracellular Vesicles in Health and Disease: A Methodological Perspective

    Brenna, S., Krisp, C., Altmeppen, H. C., Magnus, T. & Puig, B., 29.01.2021, In: INT J MOL SCI. 22, 3, p. 1365

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  16. C5a receptor (CD88) inhibition improves hypothermia-induced neuroprotection in an in vitro ischemic model.

    Thundyil, J., Pavlovski, D., Hsieh, Y-H., Gelderblom, M., Magnus, T., Fairlie, D. P. & Arumugam, T. V., 2012, In: NEUROMOL MED. 14, 1, p. 30-39 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Calorie restriction and stroke.

    Manzanero, S., Gelderblom, M., Magnus, T. & Arumugam, T. V., 2011, In: Exp Transl Stroke Med. 3, p. 8

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke

    Ludewig, P., Sedlacik, J., Gelderblom, M., Bernreuther, C., Korkusuz, Y., Wagener, C., Gerloff, C., Fiehler, J., Magnus, T. & Horst, A. K., 27.09.2013, In: CIRC RES. 113, 8, p. 1013-22 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. CCR6 (CC Chemokine Receptor 6) Is Essential for the Migration of Detrimental Natural Interleukin-17-Producing γδ T Cells in Stroke

    Arunachalam, P., Ludewig, P., Melich, P., Arumugam, T. V., Gerloff, C., Prinz, I., Magnus, T. & Gelderblom, M., 07.2017, In: STROKE. 48, 7, p. 1957-1965 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. CD38 exacerbates focal cytokine production, postischemic inflammation and brain injury after focal cerebral ischemia.

    Choe, C-U., Lardong, K., Gelderblom, M., Ludewig, P., Leypoldt, F., Koch Nolte, F., Gerloff, C. & Magnus, T., 2011, In: PLOS ONE. 6, 5, p. 19046 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression

    Schneider, E., Winzer, R., Rissiek, A., Ricklefs, I., Meyer-Schwesinger, C., Ricklefs, F. L., Bauche, A., Behrends, J., Reimer, R., Brenna, S., Wasielewski, H., Lauten, M., Rissiek, B., Puig, B., Cortesi, F., Magnus, T., Fliegert, R., Müller, C. E., Gagliani, N. & Tolosa, E., 08.10.2021, In: NAT COMMUN. 12, 1, p. 5911

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Cerebral Hemodynamics in Patients with Hemolytic Uremic Syndrome Assessed by Susceptibility Weighted Imaging and Four-Dimensional Non-Contrast MR Angiography

    Löbel, U., Forkert, N. D., Schmitt, P., Dohrmann, T. W., Schroeder, M., Magnus, T., Kluge, S., Weiler-Normann, C., Bi, X., Fiehler, J. & Sedlacik, J., 2016, In: PLOS ONE. 11, 11, p. e0164863

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Cerebral Magnetic Resonance Imaging Findings in Adults with Haemolytic Uraemic Syndrome Following an Infection with Escherichia coli, Subtype O104:H4

    Löbel, U., Eckert, B., Simova, O., Meier-Cillien, M., Kluge, S., Gerloff, C., Röther, J., Magnus, T. & Fiehler, J., 01.06.2014, In: CLIN NEURORADIOL. 24, 2, p. 111-9 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Characterization of Extracranial Giant Cell Arteritis with Intracranial Involvement and its Rapidly Progressive Subtype

    Beuker, C., Wankner, M. C., Thomas, C., Strecker, J-K., Schmidt-Pogoda, A., Schwindt, W., Schulte-Mecklenbeck, A., Gross, C., Wiendl, H., Barth, P. J., Eckert, B., Meinel, T. R., Arnold, M., Schaumberg, J., Krüger, S., Deb-Chatterji, M., Magnus, T., Röther, J. & Minnerup, J., 07.2021, In: ANN NEUROL. 90, 1, p. 118-129 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Circulating Endothelial Cells as Promising Biomarkers in the Differential Diagnosis of Primary Angiitis of the Central Nervous System

    Deb-Chatterji, M., Pinnschmidt, H. O., Duan, Y., Haeussler, V., Rissiek, B., Gerloff, C., Thomalla, G. & Magnus, T., 2020, In: FRONT NEUROL. 11, p. 205

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Clinical features of critically ill patients with Shiga toxin-induced hemolytic uremic syndrome

    Braune, S. A., Wichmann, D., Heinz, M. C., Nierhaus, A., Becker, H., Meyer, T. N., Meyer, G. P., Müller-Schulz, M., Fricke, J., de Weerth, A., Höpker, W-W., Fiehler, J., Magnus, T., Gerloff, C., Panzer, U., Stahl, R. A. K., Wegscheider, K. & Kluge, S., 01.07.2013, In: CRIT CARE MED. 41, 7, p. 1702-10 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Combined Blockade of TIGIT and CD39 or A2AR Enhances NK-92 Cell-Mediated Cytotoxicity in AML

    Brauneck, F., Seubert, E., Wellbrock, J., Schulze Zur Wiesch, J., Duan, Y., Magnus, T., Bokemeyer, C., Koch-Nolte, F., Menzel, S. & Fiedler, W., 29.11.2021, In: INT J MOL SCI. 22, 23, 12919.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Correction: Cerebral Hemodynamics in Patients with Hemolytic Uremic Syndrome Assessed by Susceptibility Weighted Imaging and Four-Dimensional Non-Contrast MR Angiography

    Löbel, U., Forkert, N. D., Schmitt, C. P., Dohrmann, T., Schroeder, M., Magnus, T., Kluge, S., Weiler-Normann, C., Bi, X., Fiehler, J. & Sedlacik, J., 2017, In: PLOS ONE. 12, 2, p. e0172450

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  29. Current Approaches and Future Perspectives for Nanobodies in Stroke Diagnostic and Therapy

    Jank, L., Pinto-Espinoza, C., Duan, Y., Koch-Nolte, F., Magnus, T. U. & Rissiek, B., 03.01.2019, In: ANTIBODIES.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Danger signals in stroke

    Gelderblom, M., Sobey, C. G., Kleinschnitz, C. & Magnus, T., 11.2015, In: AGEING RES REV. 24, Pt A, Special Issue, p. 77-82 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Danger signals in stroke and their role on microglia activation after ischemia

    Gülke, E., Gelderblom, M. & Magnus, T., 2018, In: THER ADV NEUROL DISO. 11, p. 1-14

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  32. Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation

    Gelderblom, M., Neumann, M., Ludewig, P., Bernreuther, C., Krasemann, S., Arunachalam, P., Gerloff, C., Glatzel, M. & Magnus, T., 01.01.2013, In: PLOS ONE. 8, 5, p. e63118

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Deficits in developmental neurogenesis and dendritic spine maturation in mice lacking the serine protease inhibitor neuroserpin

    Hermann, M., Reumann, R., Schostak, K., Kement, D., Gelderblom, M., Bernreuther, C., Frischknecht, R., Schipanski, A., Marik, S., Krasemann, S., Sepulveda-Falla, D., Schweizer, M., Magnus, T., Glatzel, M. & Galliciotti, G., 01.2020, In: MOL CELL NEUROSCI. 102, p. 103420

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs

    Gallizioli, M., Miró-Mur, F., Otxoa-de-Amezaga, A., Cugota, R., Salas-Perdomo, A., Justicia, C., Brait, V. H., Ruiz-Jaén, F., Arbaizar-Rovirosa, M., Pedragosa, J., Bonfill-Teixidor, E., Gelderblom, M., Magnus, T., Cano, E., Del Fresno, C., Sancho, D. & Planas, A. M., 20.10.2020, In: CELL REP. 33, 3, p. 108291

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Dendritic cells in brain diseases

    Ludewig, P., Gallizioli, M., Urra, X., Behr, S., Brait, V. H., Gelderblom, M., Magnus, T. & Planas, A. M., 03.2016, In: BBA-MOL BASIS DIS. 1862, 3, p. 352-67 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging

    Graeser, M., Ludewig, P., Szwargulski, P., Foerger, F., Liebing, T., Forkert, N. D., Thieben, F., Magnus, T. & Knopp, T., 23.12.2020, In: PHYS MED BIOL. 65, 23, p. 235007

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model

    Ramírez-Fernández, A., Urbina-Treviño, L., Conte, G., Alves, M., Rissiek, B., Durner, A., Scalbert, N., Zhang, J., Magnus, T., Koch-Nolte, F., Plesnila, N., Deussing, J. M., Engel, T., Kopp, R. & Nicke, A., 16.11.2020, In: SCI REP-UK. 10, 1, p. 19876

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Dimethylarginine dimethylaminohydrolase1 is an organ-specific mediator of end organ damage in a murine model of hypertension.

    Sydow, K., Schmitz, C., von Leitner, E-C., von Leitner, R., Klinke, A., Atzler, D., Krebs, C., Wieboldt, H., Ehmke, H., Schwedhelm, E., Meinertz, T., Blankenberg, S., Böger, R. H., Magnus, T., Baldus, S. & Wenzel, U., 2012, In: PLOS ONE. 7, 10, p. 48150 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor response.

    Cassiani-Ingoni, R., Muraro, P. A., Magnus, T., Reichert-Scrivner, S., Schmidt, J., Huh, J., Quandt, J. A., Bratincsak, A., Shahar, T., Eusebi, F., Sherman, L. S., Mattson, M. P., Martin, R. & Rao, M. S., 2007, In: J NEUROPATH EXP NEUR. 66, 7, p. 637-649 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Dynamics of brain perfusion and cognitive performance in revascularization of carotid artery stenosis

    Schröder, J., Heinze, M., Günther, M., Cheng, B., Nickel, A., Schröder, T., Fischer, F., Kessner, S. S., Magnus, T., Fiehler, J., Larena-Avellaneda, A., Gerloff, C. & Thomalla, G., 13.03.2019, In: NEUROIMAGE-CLIN. 22, p. 101779

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia

    Rissiek, B., Menzel, S., Leutert, M., Cordes, M., Behr, S., Jank, L., Ludewig, P., Gelderblom, M., Rissiek, A., Adriouch, S., Haag, F., Hottiger, M. O., Koch-Nolte, F. & Magnus, T., 28.11.2017, In: SCI REP-UK. 7, 1, p. 16477

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Edema is not a reliable diagnostic sign to exclude small brain metastases

    Schneider, T., Kuhne, J. F., Bittrich, P., Schroeder, J., Magnus, T., Mohme, M., Grosser, M., Schoen, G., Fiehler, J. & Siemonsen, S., 11.05.2017, In: PLOS ONE. 12, 5, p. e0177217

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Effective targeting of microglial P2X7 following intracerebroventricular delivery of nanobodies and nanobody-encoding AAVs

    Pinto-Espinoza, C., Guillou, C., Rissiek, B., Wilmes, M., Javidi, E., Schwarz, N., Junge, M., Haag, F., Liaukouskaya, N., Wanner, N., Nicke, A., Stortelers, C., Tan, Y-V., Adriouch, S., Magnus, T. & Koch-Nolte, F., 2022, In: FRONT PHARMACOL. 13, 1029236.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models in vivo

    Demeules, M., Scarpitta, A., Hardet, R., Gondé, H., Abad, C., Blandin, M., Menzel, S., Duan, Y., Rissiek, B., Magnus, T., Mann, A. M., Koch-Nolte, F. & Adriouch, S., 2022, In: FRONT IMMUNOL. 13, 1012534.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke

    Cheng, Y-L., Park, J-S., Manzanero, S., Choi, Y., Baik, S-H., Okun, E., Gelderblom, M., Fann, D. Y-W., Magnus, T., Launikonis, B. S., Mattson, M. P., Sobey, C. G., Jo, D-G. & Arumugam, T. V., 01.02.2014, In: NEUROBIOL DIS. 62, p. 286-95 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke.

    Arumugam, T. V., Cheng, Y-L., Choi, Y., Choi, Y-H., Yang, S., Yun, Y-K., Park, J-S., Yang, D. K., Thundyil, J., Gelderblom, M., Karamyan, V. T., Tang, S-C., Chan, S. L., Magnus, T., Sobey, C. G. & Jo, D-G., 2011, In: MOL PHARMACOL. 80, 1, p. 23-31 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes.

    Magnus, T., Coksaygan, T., Korn, T., Xue, H., Arumugam, T. V., Mughal, M. R., Eckley, D. M., Tang, S-C., Detolla, L., Rao, M. S., Cassiani-Ingoni, R. & Mattson, M. P., 2007, In: J NEUROSCI RES. 85, 10, p. 2126-2137 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Fatal PCR-negative herpes simplex virus-1 encephalitis with GABAA receptor antibodies

    Schuster, S., Abrante, L., Matschke, J., Lütgehetmann, M., Holst, B., Gelderblom, M., Braass, H., Leypoldt, F. & Magnus, T., 11.2019, In: NEUROL-NEUROIMMUNOL. 6, 6

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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