PD Dr. med. ID: 43961

Tim Ullrich Magnus

graph of relations

Publications

  1. 2023
  2. Homoarginine Associates with Carotid Intima-Media Thickness and Atrial Fibrillation and Predicts Adverse Events after Stroke

    Schwieren, L., Jensen, M., Schulz, R., Lezius, S., Laxy, E., Milatz, M., Thomalla, G., Böger, R., Gerloff, C., Magnus, T., Schwedhelm, E. & Choe, C-U., 20.07.2023, In: LIFE-BASEL. 13, 7, 1590.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Blood neurofilament light chain in Parkinson's disease

    Buhmann, C., Magnus, T. & Choe, C-U., 06.2023, In: J NEURAL TRANSM. 130, 6, p. 755-762 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  4. The role of the ATP-adenosine axis in ischemic stroke

    Schädlich, I. S., Winzer, R., Stabernack, J., Tolosa, E., Magnus, T. & Rissiek, B., 05.2023, In: SEMIN IMMUNOPATHOL. 45, 3, p. 347-365 19 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  5. Unveiling the immunopathology of stroke: a comprehensive view on brain-immune interaction

    Magnus, T. & Liesz, A., 05.2023, In: SEMIN IMMUNOPATHOL. 45, 3, p. 279-280 2 p.

    Research output: SCORING: Contribution to journalEditorialResearch

  6. Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system-No evidence for the role of neuronal P2X7 receptors in colitis

    Jooss, T., Zhang, J., Zimmer, B., Rezzonico-Jost, T., Rissiek, B., Felipe Pelczar, P., Seehusen, F., Koch-Nolte, F., Magnus, T., Zierler, S., Huber, S., Schemann, M., Grassi, F. & Nicke, A., 04.2023, In: MUCOSAL IMMUNOL. 16, 2, p. 180-193 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. A preclinical randomized controlled multi-centre trial of anti-interleukin-17A treatment for acute ischaemic stroke

    Gelderblom, M., Koch, S., Strecker, J-K., Jørgensen, C., Garcia-Bonilla, L., Ludewig, P., Schädlich, I. S., Piepke, M., Degenhardt, K., Bernreuther, C., Pinnschmidt, H., Arumugam, T. V., Thomalla, G., Faber, C., Sedlacik, J., Gerloff, C., Minnerup, J., Clausen, B. H., Anrather, J. & Magnus, T., 23.03.2023, In: BRAIN COMMUN. 5, 2, p. fcad090

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Microglia and meningeal macrophages depletion delays the onset of experimental autoimmune encephalomyelitis

    Montilla, A., Zabala, A., Er-Lukowiak, M., Rissiek, B., Magnus, T., Rodriguez-Iglesias, N., Sierra, A., Matute, C. & Domercq, M., 12.01.2023, In: CELL DEATH DIS. 14, 1, p. 16

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. 2022
  10. Interleukin-1 Mediates Ischemic Brain Injury via Induction of IL-17A in γδ T Cells and CXCL1 in Astrocytes

    Schädlich, I. S., Vienhues, J. H., Jander, A., Piepke, M., Magnus, T., Lambertsen, K. L., Clausen, B. H. & Gelderblom, M., 12.2022, In: NEUROMOL MED. 24, 4, p. 437-451 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. P2X7 is expressed on human innate-like T lymphocytes and mediates susceptibility to ATP-induced cell death

    Winzer, R., Serracant-Prat, A., Brock, V. J., Pinto-Espinoza, C., Rissiek, B., Amadi, M., Eich, N., Rissiek, A., Schneider, E., Magnus, T., Guse, A. H., Diercks, B-P., Koch-Nolte, F. & Tolosa, E., 11.2022, In: EUR J IMMUNOL. 52, 11, p. 1805-1818 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions

    Wilmes, M., Pinto Espinoza, C., Ludewig, P., Stabernack, J., Liesz, A., Nicke, A., Gelderblom, M., Gerloff, C., Falzoni, S., Tolosa, E., Di Virgilio, F., Rissiek, B., Plesnilla, N., Koch-Nolte, F. & Magnus, T., 12.10.2022, In: J NEUROINFLAMM. 19, 1, 256.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Normalization of Aperiodic Electrocorticography Components Indicates Fine Motor Recovery After Sensory Cortical Stroke in Mice

    Biskamp, J., Isla Cainzos, S., Higgen, F. L., Gerloff, C. & Magnus, T., 09.2022, In: STROKE. 53, 9, p. 2945–2953 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Nt5e deficiency does not affect post-stroke inflammation and lesion size in a murine ischemia/reperfusion stroke model

    Schädlich, I. S., Schnapauff, O., Pöls, L., Schrader, J., Tolosa, E., Rissiek, B. & Magnus, T., 17.06.2022, In: ISCIENCE. 25, 6, 104470.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes

    Bub, A., Brenna, S., Alawi, M., Kügler, P., Gui, Y., Kretz, O., Altmeppen, H., Magnus, T. & Puig, B., 31.05.2022, In: CELL MOL LIFE SCI. 79, 6, p. 329 329.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Recurrent amnesia caused by early seizures after hippocampal infarction: A case report

    Schlemm, E., Magnus, T., Rimmele, L. D., Münsterberg, J., Bester, M., Kessner, S. S., Gelderblom, M. & Gerloff, C., 10.01.2022, In: BMC NEUROL. 22, 1, 18.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Magnetic particle imaging for assessment of cerebral perfusion and ischemia

    Ludewig, P., Graeser, M., Forkert, N. D., Thieben, F., Rández-Garbayo, J., Rieckhoff, J., Lessmann, K., Förger, F., Szwargulski, P., Magnus, T. & Knopp, T., 01.2022, In: WIRES NANOMED NANOBI. 14, 1, e1757.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  18. Effective targeting of microglial P2X7 following intracerebroventricular delivery of nanobodies and nanobody-encoding AAVs

    Pinto-Espinoza, C., Guillou, C., Rissiek, B., Wilmes, M., Javidi, E., Schwarz, N., Junge, M., Haag, F., Liaukouskaya, N., Wanner, N., Nicke, A., Stortelers, C., Tan, Y-V., Adriouch, S., Magnus, T. & Koch-Nolte, F., 2022, In: FRONT PHARMACOL. 13, 1029236.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models in vivo

    Demeules, M., Scarpitta, A., Hardet, R., Gondé, H., Abad, C., Blandin, M., Menzel, S., Duan, Y., Rissiek, B., Magnus, T., Mann, A. M., Koch-Nolte, F. & Adriouch, S., 2022, In: FRONT IMMUNOL. 13, 1012534.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Real-Time Flow Cytometry as a Tool to Monitor Cellular Consequences of P2X7 Activation in Multiple Cell Populations Mixed in a Single FACS Tube

    Veltkamp, A. W., Magnus, T. & Rissiek, B., 2022, The P2X7 Receptor: Methods and Protocols. Nicke, A. (ed.). 1 ed. New York, NY: HUMANA PRESS INC, p. 291-302 12 p. (Methods Mol Biol; vol. 2510).

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  21. 2021
  22. Serum Sphingosine-1-Phosphate Levels Are Associated With Severity and Outcome in Patients With Cerebral Ischemia

    Schwedhelm, E., Schwieren, L., Tiedt, S., von Lucadou, M., Gloyer, N-O., Böger, R., Magnus, T., Daum, G., Thomalla, G., Gerloff, C. & Choe, C-U., 12.2021, In: STROKE. 52, 12, p. 3901-3907 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Combined Blockade of TIGIT and CD39 or A2AR Enhances NK-92 Cell-Mediated Cytotoxicity in AML

    Brauneck, F., Seubert, E., Wellbrock, J., Schulze Zur Wiesch, J., Duan, Y., Magnus, T., Bokemeyer, C., Koch-Nolte, F., Menzel, S. & Fiedler, W., 29.11.2021, In: INT J MOL SCI. 22, 23, 12919.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Interleukin-10 improves stroke outcome by controlling the detrimental Interleukin-17A response

    Piepke, M., Clausen, B. H., Ludewig, P., Vienhues, J. H., Bedke, T., Javidi, E., Rissiek, B., Jank, L., Brockmann, L., Sandrock, I., Degenhardt, K., Jander, A., Roth, V., Schädlich, I. S., Prinz, I., Flavell, R. A., Kobayashi, Y., Renné, T., Gerloff, C., Huber, S., Magnus, T. & Gelderblom, M., 13.11.2021, In: J NEUROINFLAMM. 18, 1, 265.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression

    Schneider, E., Winzer, R., Rissiek, A., Ricklefs, I., Meyer-Schwesinger, C., Ricklefs, F. L., Bauche, A., Behrends, J., Reimer, R., Brenna, S., Wasielewski, H., Lauten, M., Rissiek, B., Puig, B., Cortesi, F., Magnus, T., Fliegert, R., Müller, C. E., Gagliani, N. & Tolosa, E., 08.10.2021, In: NAT COMMUN. 12, 1, p. 5911

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. The Joint Vasculitis Registry in German-speaking countries (GeVas) - a prospective, multicenter registry for the follow-up of long-term outcomes in vasculitis

    Iking-Konert, C., Wallmeier, P., Arnold, S., Adler, S., de Groot, K., Hellmich, B., Hoyer, B. F., Holl-Ulrich, K., Ihorst, G., Kaufmann, M., Kötter, I., Müller-Ladner, U., Magnus, T., Rech, J., Schubach, F., Schulze-Koops, H., Venhoff, N., Wiech, T., Villiger, P. & Lamprecht, P., 31.07.2021, In: BMC RHEUMATOL. 5, 1, 40.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Characterization of Extracranial Giant Cell Arteritis with Intracranial Involvement and its Rapidly Progressive Subtype

    Beuker, C., Wankner, M. C., Thomas, C., Strecker, J-K., Schmidt-Pogoda, A., Schwindt, W., Schulte-Mecklenbeck, A., Gross, C., Wiendl, H., Barth, P. J., Eckert, B., Meinel, T. R., Arnold, M., Schaumberg, J., Krüger, S., Deb-Chatterji, M., Magnus, T., Röther, J. & Minnerup, J., 07.2021, In: ANN NEUROL. 90, 1, p. 118-129 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Profiling Complement System Components in Primary CNS Vasculitis

    Deb-Chatterji, M., Keller, C. W., Koch, S., Wiendl, H., Gerloff, C., Magnus, T. & Lünemann, J. D., 08.05.2021, In: CELLS-BASEL. 10, 5, 1139.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Platelet endothelial cell adhesion molecule-1 is a gatekeeper of neutrophil transendothelial migration in ischemic stroke

    Winneberger, J., Schöls, S., Lessmann, K., Rández-Garbayo, J., Bauer, A. T., Mohamud Yusuf, A., Hermann, D. M., Gunzer, M., Schneider, S. W., Fiehler, J., Gerloff, C., Gelderblom, M., Ludewig, P. & Magnus, T., 03.2021, In: BRAIN BEHAV IMMUN. 93, p. 277-287 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Brain-Derived Extracellular Vesicles in Health and Disease: A Methodological Perspective

    Brenna, S., Krisp, C., Altmeppen, H. C., Magnus, T. & Puig, B., 29.01.2021, In: INT J MOL SCI. 22, 3, p. 1365

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  31. Identification of the Mouse T Cell ADP-Ribosylome Uncovers ARTC2.2 Mediated Regulation of CD73 by ADP-Ribosylation

    Leutert, M., Duan, Y., Winzer, R., Menzel, S., Tolosa, E., Magnus, T., Hottiger, M. O., Koch-Nolte, F. & Rissiek, B., 2021, In: FRONT IMMUNOL. 12, p. 703719

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. 2020
  33. Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging

    Graeser, M., Ludewig, P., Szwargulski, P., Foerger, F., Liebing, T., Forkert, N. D., Thieben, F., Magnus, T. & Knopp, T., 23.12.2020, In: PHYS MED BIOL. 65, 23, p. 235007

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice

    Er-Lukowiak, M., Duan, Y., Rassendren, F., Ulmann, L., Nicke, A., Ufer, F., Friese, M. A., Koch-Nolte, F., Magnus, T. & Rissiek, B., 18.12.2020, In: ISCIENCE. 23, 12, p. 101870

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model

    Ramírez-Fernández, A., Urbina-Treviño, L., Conte, G., Alves, M., Rissiek, B., Durner, A., Scalbert, N., Zhang, J., Magnus, T., Koch-Nolte, F., Plesnila, N., Deussing, J. M., Engel, T., Kopp, R. & Nicke, A., 16.11.2020, In: SCI REP-UK. 10, 1, p. 19876

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Monitoring Intracranial Cerebral Hemorrhage Using Multicontrast Real-Time Magnetic Particle Imaging

    Szwargulski, P., Wilmes, M., Javidi, E., Thieben, F., Graeser, M., Koch, M., Gruettner, C., Adam, G., Gerloff, C., Magnus, T., Knopp, T. & Ludewig, P., 27.10.2020, In: ACS NANO. 14, 10, p. 13913-13923 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs

    Gallizioli, M., Miró-Mur, F., Otxoa-de-Amezaga, A., Cugota, R., Salas-Perdomo, A., Justicia, C., Brait, V. H., Ruiz-Jaén, F., Arbaizar-Rovirosa, M., Pedragosa, J., Bonfill-Teixidor, E., Gelderblom, M., Magnus, T., Cano, E., Del Fresno, C., Sancho, D. & Planas, A. M., 20.10.2020, In: CELL REP. 33, 3, p. 108291

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Show Me Your Friends and I Tell You Who You Are: The Many Facets of Prion Protein in Stroke

    Puig, B., Yang, D., Brenna, S., Altmeppen, H. C. & Magnus, T., 02.07.2020, In: CELLS-BASEL. 9, 7

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  39. Homoarginine- and Creatine-Dependent Gene Regulation in Murine Brains with l-Arginine:Glycine Amidinotransferase Deficiency

    Jensen, M., Müller, C., Schwedhelm, E., Arunachalam, P., Gelderblom, M., Magnus, T., Gerloff, C., Zeller, T. & Choe, C-U., 09.03.2020, In: INT J MOL SCI. 21, 5, 1865.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Intravenous Immunoglobulin (IVIg) Induce a Protective Phenotype in Microglia Preventing Neuronal Cell Death in Ischaemic Stroke

    Häußler, V., Daehn, T., Rissiek, B., Roth, V., Gerloff, C., Arumugam, T. V., Magnus, T. & Gelderblom, M., 03.2020, In: NEUROMOL MED. 22, 1, p. 121-132 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Astrocytes and Microglia Are Resistant to NAD+-Mediated Cell Death Along the ARTC2/P2X7 Axis

    Rissiek, B., Stabernack, J., Cordes, M., Duan, Y., Behr, S., Menzel, S., Magnus, T. & Koch-Nolte, F., 01.2020, In: FRONT MOL NEUROSCI. 12, p. 330

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Deficits in developmental neurogenesis and dendritic spine maturation in mice lacking the serine protease inhibitor neuroserpin

    Hermann, M., Reumann, R., Schostak, K., Kement, D., Gelderblom, M., Bernreuther, C., Frischknecht, R., Schipanski, A., Marik, S., Krasemann, S., Sepulveda-Falla, D., Schweizer, M., Magnus, T., Glatzel, M. & Galliciotti, G., 01.2020, In: MOL CELL NEUROSCI. 102, p. 103420

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Circulating Endothelial Cells as Promising Biomarkers in the Differential Diagnosis of Primary Angiitis of the Central Nervous System

    Deb-Chatterji, M., Pinnschmidt, H. O., Duan, Y., Haeussler, V., Rissiek, B., Gerloff, C., Thomalla, G. & Magnus, T., 2020, In: FRONT NEUROL. 11, p. 205

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Safety and efficacy of intravenous thrombolysis in stroke patients on prior antiplatelet therapy in the WAKE-UP trial

    Frey, B. M., Boutitie, F., Cheng, B., Cho, T-H., Ebinger, M., Endres, M., Fiebach, J. B., Fiehler, J., Ford, I., Galinovic, I., Königsberg, A., Puig, J., Roy, P., Wouters, A., Magnus, T., Thijs, V., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Gerloff, C., Thomalla, G. & WAKE-UP Investigators, 2020, In: Neurol Res Pract. 2, p. 40

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. 2019
  46. Fatal PCR-negative herpes simplex virus-1 encephalitis with GABAA receptor antibodies

    Schuster, S., Abrante, L., Matschke, J., Lütgehetmann, M., Holst, B., Gelderblom, M., Braass, H., Leypoldt, F. & Magnus, T., 11.2019, In: NEUROL-NEUROIMMUNOL. 6, 6

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Induction of immunological tolerance to myelinogenic glial-restricted progenitor allografts

    Li, S., Chol Oh, B., Arnold, A., Jablonska, A., Furtmüller, G., Qin, H-M., Boltze, J., Magnus, T. U., Ludewig, P., Janowski, M., Brandacher, G. & Walczak, P., 16.09.2019, In: BRAIN.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Primary Angiitis of the Central Nervous System: New Potential Imaging Techniques and Biomarkers in Blood and Cerebrospinal Fluid

    Deb-Chatterji, M., Schuster, S., Haeussler, V., Gerloff, C., Thomalla, G. & Magnus, T., 06.06.2019, In: FRONT NEUROL. 10, p. 568

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  49. Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the WAKE-UP Trial

    Barow, E., Boutitie, F., Cheng, B., Cho, T-H., Ebinger, M., Endres, M., Fiebach, J. B., Fiehler, J., Ford, I., Galinovic, I., Nickel, A., Puig, J., Roy, P., Wouters, A., Magnus, T., Thijs, V., Lemmens, R., Muir, K. W., Nighoghossian, N., Pedraza, S., Simonsen, C. Z., Gerloff, C., Thomalla, G. & WAKE-UP Investigators, 01.06.2019, In: JAMA NEUROL. 76, 6, p. 641-649 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Relapse rates and long-term outcome in primary angiitis of the central nervous system

    Schuster, S., Ozga, A-K., Stellmann, J-P., Deb-Chatterji, M., Häußler, V., Matschke, J., Gerloff, C., Thomalla, G. & Magnus, T., 06.2019, In: J NEUROL. 266, 6, p. 1481-1489 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Autoimmunity After Ischemic Stroke and Brain Injury

    Javidi, E. & Magnus, T. U., 02.04.2019, In: FRONT IMMUNOL.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  52. Dynamics of brain perfusion and cognitive performance in revascularization of carotid artery stenosis

    Schröder, J., Heinze, M., Günther, M., Cheng, B., Nickel, A., Schröder, T., Fischer, F., Kessner, S. S., Magnus, T., Fiehler, J., Larena-Avellaneda, A., Gerloff, C. & Thomalla, G., 13.03.2019, In: NEUROIMAGE-CLIN. 22, p. 101779

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. Neuroradiologic Characteristics of Primary Angiitis of the Central Nervous System According to the Affected Vessel Size

    Thaler, C., Kaufmann-Bühler, A-K., Gansukh, T., Gansukh, A., Schuster, S., Bachmann, H., Thomalla, G., Magnus, T., Matschke, J., Fiehler, J. & Siemonsen, S., 03.2019, In: CLIN NEURORADIOL. 29, 1, p. 37-44 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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