Dr.rer.nat. ID: 41291
Rene Werner
Publications
- 2024
Spatial normalization for voxel-based lesion symptom mapping: impact of registration approaches
Jühling, D., Rajashekar, D., Cheng, B., Hilgetag, C. C., Forkert, N. D. & Werner, R., 17.01.2024, In: FRONT NEUROSCI-SWITZ. 18, p. 1296357Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DARTS: an open-source Python pipeline for Ca2+ microdomain analysis in live cell imaging data
Woelk, L-M., Kovacevic, D., Husseini, H., Förster, F., Gerlach, F., Möckl, F., Altfeld, M., Guse, A. H., Diercks, B-P. & Werner, R., 11.01.2024, In: FRONT IMMUNOL. 14, p. 1299435Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deep Image Prior for Spatio-temporal Fluorescence Microscopy Images: DECO-DIP
Meyer, L., Woelk, L-M., Gee, C., Lohr, C., Arcot Kannabiran, S., Diercks, B-P. & Werner, R., 2024, Bildverarbeitung für die Medizin 2024: Proceedings, German Conference on Medical Image Computing, Erlangen, March 10–12, 2024. Maier, A., Deserno, TM., Handels, H., Maier-Hein, K., Palm, C. & Tolxdorff, TM. (eds.). 1 ed. Springer Vieweg, p. 322-327 6 p. (Informatik Aktuell).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Time-resolved role of P2X4 and P2X7 during CD8+ T cell activation
Brock, V. J., Lory, N. C., Möckl, F., Birus, M., Stähler, T., Woelk, L-M., Jaeckstein, M., Heeren, J., Koch-Nolte, F., Rissiek, B., Mittrücker, H-W., Guse, A. H., Werner, R. & Diercks, B-P., 2024, In: FRONT IMMUNOL. 15, p. 1258119Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Dose reduction in sequence scanning 4D CT imaging through respiratory signal-guided tube current modulation: A feasibility study
Schwarz, A., Werner, R., Wimmert, L., Vornehm, M., Gauer, T. & Hofmann, C., 12.2023, In: MED PHYS. 50, 12, p. 7539-7547 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Self-Supervision for Medical Image Classification: State-of-the-Art Performance with ~100 Labeled Training Samples per Class
Nielsen, M., Wenderoth, L., Sentker, T. & Werner, R., 28.07.2023, In: BIOENGINEERING-BASEL. 10, 8, 14 p., 895.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical application of breathing-adapted 4D CT: image quality comparison to conventional 4D CT
Werner, R., Szkitsak, J., Madesta, F., Büttgen, L., Wimmert, L., Sentker, T., Fietkau, R., Haderlein, M., Bert, C., Gauer, T. & Hofmann, C., 07.2023, In: STRAHLENTHER ONKOL. 199, 7, p. 686-691 6 p.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Adhesion to laminin-1 and collagen IV induces the formation of Ca2+ microdomains that sensitize mouse T cells for activation
Weiß, M., Hernandez, L. C., Gil Montoya, D. C., Löhndorf, A., Krüger, A., Kopdag, M., Uebler, L., Landwehr, M., Nawrocki, M., Huber, S., Woelk, L-M., Werner, R., Failla, A. V., Flügel, A., Dupont, G., Guse, A. H. & Diercks, B-P., 20.06.2023, In: SCIENCE SIGNALING. 16, 790, p. eabn9405Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Extending Tempcyclegan for Virtual Augmentation of Gastrointestinal Endoscopy Training Simulators
Wallrodt, M., Schulz-Alsen, M., Ehlken, H., Rösch, T., Schmitz, R. & Werner, R., 02.06.2023, Bildverarbeitung für die Medizin 2023: Proceedings, German Workshop on Medical Image Computing, Braunschweig, July 2-4, 2023. Deserno, T. M., Handels, H., Maier, A., Maier-Hein, K., Palm, C. & Tolxdorff, T. (eds.). 1 ed. Springer Vieweg, p. 3-8 6 p. (Informatik aktuell).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Label Efficient Classification in Liquid Biopsy Data by Self-supervision
Husseini, H., Nielsen, M., Pantel, K., Wikman, H., Riethdorf, S. & Werner, R., 02.06.2023, Bildverarbeitung für die Medizin 2023: Proceedings, German Workshop on Medical Image Computing, Braunschweig, July 2-4, 2023. Deserno, T. M., Handels, H., Maier, A., Maier-Hein, K., Palm, C. & Tolxdorff, T. (eds.). 1 ed. Springer Vieweg, p. 261-266 6 p. (Informatik aktuell).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Discordant and Converting Receptor Expressions in Brain Metastases from Breast Cancer: MRI-Based Non-Invasive Receptor Status Tracking
Heitkamp, A., Madesta, F., Amberg, S., Wahaj, S., Schröder, T., Bechstein, M., Meyer, L., Broocks, G., Hanning, U., Gauer, T., Werner, R., Fiehler, J., Gellißen, S. & Kniep, H. C., 23.05.2023, In: CANCERS. 15, 11, 2880.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Dekonvolution von Mikroskopiedaten bei niedrigem Signal-Rausch-Verhältnis
Woelk, L-M., Diercks, B-P. & Werner, R., 11.2022, In: BIOspektrum. 2022, 28, p. 720-722Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evaluation of magnetic resonance imaging-based radiomics characteristics for differentiation of benign and malignant peripheral nerve sheath tumors in neurofibromatosis type 1
Ristow, I., Madesta, F., Well, L., Shenas, F. Y., Wright, F., Molwitz, I., Farschtschi, S., Bannas, P., Adam, G., Mautner, V. F., Werner, R. & Salamon, J., 03.10.2022, In: NEURO-ONCOLOGY. 24, 10, p. 1790-1798 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reinforcement learning-basierte Patchpriorisierung zur beschleunigten Segmentierung von hochauflösenden Endoskopievideodaten
Schüttler, S., Madesta, F., Rösch, T., Werner, R. & Schmitz, R., 05.04.2022, Informatik aktuell: Bildverarbeitung für die Medizin. Klaus, M-H., Deserno, T. M., Handels, H., Maier, A., Palm, C. & Tolxdorff, T. (eds.). 1 ed. Wiesbaden: Springer Vieweg, p. 339-344 6 p. (Bildverarbeitung für die Medizin 2022).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Artificial intelligence in GI endoscopy: stumbling blocks, gold standards and the role of endoscopy societies
Schmitz, R., Werner, R., Repici, A., Bisschops, R., Meining, A., Zornow, M., Messmann, H., Hassan, C., Sharma, P. & Rösch, T., 03.2022, In: GUT. 71, 3, p. 451-454 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
P2X4 and P2X7 are essential players in basal T cell activity and Ca2+ signaling milliseconds after T cell activation
Brock, V. J., Wolf, I. M. A., Er-Lukowiak, M., Lory, N., Stähler, T., Woelk, L-M., Mittrücker, H-W., Müller, C. E., Koch-Nolte, F., Rissiek, B., Werner, R., Guse, A. H. & Diercks, B-P., 04.02.2022, In: SCI ADV. 8, 5, eabl9770.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation
Gu, F., Krüger, A., Roggenkamp, H. G., Alpers, R., Lodygin, D., Jaquet, V., Möckl, F., Hernandez C, L. C., Winterberg, K., Bauche, A., Rosche, A., Grasberger, H., Kao, J. Y., Schetelig, D., Werner, R., Schröder, K., Carty, M., Bowie, A. G., Huber, S., Meier, C., Mittrücker, H-W., Heeren, J., Krause, K-H., Flügel, A., Diercks, B-P. & Guse, A. H., 16.11.2021, In: SCIENCE SIGNALING. 14, 709, eabe3800.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deep Learning-Based Automated Thrombolysis in Cerebral Infarction Scoring: A Timely Proof-of-Principle Study
Nielsen, M., Waldmann, M., Frölich, A. M., Flottmann, F., Hristova, E., Bendszus, M., Seker, F., Fiehler, J., Sentker, T. & Werner, R., 11.2021, In: STROKE. 52, 11, p. 3497-3504 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Time-Dependent Image Restoration of Low-SNR Live-Cell Ca2+ Fluorescence Microscopy Data
Woelk, L-M., Kannabiran, S. A., Brock, V. J., Gee, C. E., Lohr, C., Guse, A. H., Diercks, B-P. & Werner, R., 30.10.2021, In: INT J MOL SCI. 22, 17 p., 11792.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
First clinical evaluation of breathing controlled four-dimensional computed tomography imaging
Szkitsak, J., Werner, R., Fernolendt, S., Schwarz, A., Ott, O. J., Fietkau, R., Hofmann, C. & Bert, C., 10.2021, In: PHYS IMAG RADIAT ONC. 20, p. 56-61 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multi-scale fully convolutional neural networks for histopathology image segmentation: From nuclear aberrations to the global tissue architecture
Schmitz, R., Madesta, F., Nielsen, M., Krause, J., Steurer, S., Werner, R. & Rösch, T., 05.2021, In: MED IMAGE ANAL. 70, p. 101996 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Spatio-temporal feature learning with reservoir computing for T-cell segmentation in live-cell Ca2+ fluorescence microscopy
Hadaeghi, F., Diercks, B-P., Schetelig, D., Damicelli, F., Wolf, I. M. A. & Werner, R., 15.04.2021, In: SCI REP-UK. 11, 1, 8233.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation
Roggenkamp, H. G., Khansahib, I., Hernandez C, L. C., Zhang, Y., Lodygin, D., Krüger, A., Gu, F., Möckl, F., Löhndorf, A., Wolters, V., Woike, D., Rosche, A., Bauche, A., Schetelig, D., Werner, R., Schlüter, H., Failla, A. V., Meier, C., Fliegert, R., Walseth, T. F., Flügel, A., Diercks, B-P. & Guse, A. H., 23.03.2021, In: SCI SIGNAL. 14, 675Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of intelligent 4D CT sequence scanning and conventional spiral 4D CT: a first comprehensive phantom study
Werner, R., Szkitsak, J., Sentker, T., Madesta, F., Schwarz, A., Fernolendt, S., Vornehm, M., Gauer, T., Bert, C. & Hofmann, C., 08.01.2021, In: PHYS MED BIOL. 66, 1, 10 p., 015004.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PAIP 2019: Liver cancer segmentation challenge
Kim, Y. J., Jang, H., Lee, K., Park, S., Min, S-G., Hong, C., Park, J. H., Lee, K., Kim, J., Hong, W., Jung, H., Liu, Y., Rajkumar, H., Khened, M., Krishnamurthi, G., Yang, S., Wang, X., Han, C. H., Kwak, J. T., Ma, J., Tang, Z., Marami, B., Zeineh, J., Zhao, Z., Heng, P-A., Schmitz, R., Madesta, F., Rösch, T., Werner, R., Tian, J., Puybareau, E., Bovio, M., Zhang, X., Zhu, Y., Chun, S. Y., Jeong, W-K., Park, P. & Choi, J., 01.2021, In: MED IMAGE ANAL. 67, p. 101854 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reduktion der Kalibrierungszeit für die Magnetpartikelbildgebung mittels Deep Learning
Baltruschat, I. M., Szwargulski, P., Griese, F., Grosser, M., Werner, R. & Knopp, T., 2021, Bildverarbeitung für die Medizin 2021 - Proceedings, German Workshop on Medical Image Computing, 2021. Palm, C., Handels, H., Maier-Hein, K., Deserno, T. M., Maier, A. & Tolxdorff, T. (eds.). Springer Science and Business Media Deutschland GmbH, p. 337 1 p. (Informatik aktuell).Research output: SCORING: Contribution to book/anthology › Conference contribution - Article for conference › Research › peer-review
Single Image-Based Vignetting Correction for Improving the Consistency of Neural Activity Analysis in 2-Photon Functional Microscopy
Li, D., Wang, G., Werner, R., Xie, H., Guan, J-S. & Hilgetag, C-C., 2021, In: FRONT NEUROINFORM. 15, p. 674439 674439.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Digital Health meets Hamburg integrated medical degree program iMED: Concept and introduction of the new interdisciplinary 2nd track Digital Health
Werner, R., Henningsen, M., Schmitz, R., Guse, A. H., Augustin, M. & Gauer, T., 16.11.2020, In: GMS Journal for Medical Education. 37, 6, p. Doc61 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Education › peer-review
Self-contained deep learning-based boosting of 4D cone-beam CT reconstruction
Madesta, F., Sentker, T., Gauer, T. & Werner, R., 11.2020, In: MED PHYS. 47, 11, p. 5619-5631 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Künstliche Intelligenz in der Medizin
Werner, R. & Schmitz, R., 21.10.2020, Digitale Medizin. Matusiewicz, D., Henningsen, M. & Ehlers, J. P. (eds.). 1 ed. Medizinisch Wissenschaftliche Verlagsgesellschaft, p. 125-138 14 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
3d-SMRnet: Achieving a New Quality of MPI System Matrix Recovery by Deep Learning
Baltruschat, I. M., Szwargulski, P. K., Griese, F., Grosser, M., Werner, R. & Knopp, T., 10.2020, Medical Image Computing and Computer Assisted Intervention – MICCAI 2020: 23rd International Conference, Lima, Peru, October 4–8, 2020, Proceedings, Part II. 1 ed. Springer Nature Switzerland, p. 74-82 9 p. (Lecture Notes in Computer Science (LNCS); no. 12262).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Time Matters: Handling Spatio-Temporal Perfusion Information for Automated TICI Scoring
Nielsen, M., Waldmann, M., Sentker, T., Frölich, A., Fiehler, J. & Werner, R., 10.2020, MICCAI 2020. 1 ed. Springer Nature Switzerland, Vol. 12266. p. 86-96 11 p. (Lecture Notes in Computer Science (LNCS)).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Widening the Focus: Biomedical Image Segmentation Challenges and the Underestimated Role of Patch Sampling and Inference Strategies
Madesta, F., Schmitz, R., Rösch, T. & Werner, R., 10.2020, MICCAI 2020. 1 ed. Springer Nature Switzerland, Vol. 12264. p. 289-298 10 p. (Lecture Notes in Computer Science (LNCS)).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
4D CT image artifacts affect local control in SBRT of lung and liver metastases
Sentker, T., Schmidt, V., Ozga, A-K., Petersen, C., Madesta, F., Hofmann, C., Werner, R. & Gauer, T., 07.2020, In: RADIOTHER ONCOL. 148, p. 229-234 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intelligent 4D CT sequence scanning (i4DCT): First scanner prototype implementation and phantom measurements of automated breathing signal-guided 4D CT
Werner, R., Sentker, T., Madesta, F., Schwarz, A., Vornehm, M., Gauer, T. & Hofmann, C., 06.2020, In: MED PHYS. 47, 6, p. 2408-2412 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Technological quality requirements for stereotactic radiotherapy: Expert review group consensus from the DGMP Working Group for Physics and Technology in Stereotactic Radiotherapy
Schmitt, D., Blanck, O., Gauer, T., Fix, M. K., Brunner, T. B., Fleckenstein, J., Loutfi-Krauss, B., Manser, P., Werner, R., Wilhelm, M-L., Baus, W. W. & Moustakis, C., 05.2020, In: STRAHLENTHER ONKOL. 196, 5, p. 421-443 23 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Reservoir Computing for Jurkat T-cell Segmentation in High Resolution Live Cell Ca2+ Fluorescence Microscopy
Hadäghi, F., Diercks, B-P., Wolf, I. & Werner, R., 01.04.2020, In: Proc IEEE ISBI 2020. 1, p. 1587-1591 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Combining Direct 3D Volume Rendering and Magnetic Particle Imaging to Advance Radiation-Free Real-Time 3D Guidance of Vascular Interventions
Weller, D., Salamon, J. M., Frölich, A., Möddel, M., Knopp, T. & Werner, R., 02.2020, In: CARDIOVASC INTER RAD. 43, 2, p. 322-330 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Skin Lesion Classification Using CNNs with Patch-Based Attention and Diagnosis-Guided Loss Weighting
Gessert, N., Sentker, T., Madesta, F., Schmitz, R., Kniep, H., Baltruschat, I., Werner, R. & Schlaefer, A., 02.2020, In: IEEE T BIO-MED ENG. 67, 2, p. 495-503 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Künstliche Intelligenz in der Endoskopie: Neuronale Netze und maschinelles Sehen – Techniken und Perspektiven (reprint Z Gastroenterol 2019; 57(06): 767-780)
Schmitz, R., Werner, R. & Rösch, T., 2020, In: Endo-Praxis. 2020, 36, p. 30-43Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Skin lesion classification using ensembles of multi-resolution EfficientNets with meta data
Gessert, N., Nielsen, M., Shaikh, M., Werner, R. & Schlaefer, A., 2020, In: METHODSX. 7, 7, p. 100864 8 p., 100864.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Intelligent 4D CT sequence scanning (i4DCT): Concept and performance evaluation
Werner, R., Sentker, T., Madesta, F., Gauer, T. & Hofmann, C., 13.08.2019, In: MED PHYS. 46, 8, p. 3462-3474 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Künstliche Intelligenz in der Endoskopie: Neuronale Netze und maschinelles Sehen – Techniken und Perspektiven
Schmitz, R., Werner, R. & Rösch, T., 06.2019, In: Z GASTROENTEROL. 57, 6, p. 767-780 14 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Discrimination of the hierarchical structure of cortical layers in 2-photon microscopy data by combined unsupervised and supervised machine learning
Li, D., Zavaglia, M., Wang, G., Xie, H., Hu, Y., Werner, R., Guan, J-S. & Hilgetag, C. C., 15.05.2019, In: SCI REP-UK. 9, 1, p. 7424Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Self-consistent deep learning-based boosting of 4D cone-beam computed tomography reconstruction
Madesta, F., Gauer, T., Sentker, T. & Werner, R., 15.03.2019, Medical Imaging 2019: Image Processing. 1 ed. SPIE , Vol. 10949. p. 1094902 6 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Toward employing the full potential of magnetic particle imaging: exploring visualization techniques and clinical use cases for real-time 3D vascular imaging
Werner, R., Weller, D., Salamon, J. M., Möddel, M. & Knopp, T., 15.03.2019, Medical Imaging 2019: Biomedical Applications in Molecular, Structural, and Functional Imaging. 1 ed. SPIE , Vol. 10953. p. 109531V 6 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Patient-specific 4D Monte Carlo dose accumulation using correspondence-model-based motion prediction
Sentker, T., Madesta, F. & Werner, R., 08.03.2019, Medical Imaging 2019: Image-Guided Procedures, Robotic Interventions, and Modeling. Fei, B. & Linte, C. A. (eds.). 1 ed. SPIE , Vol. 10951. p. 1095109 7 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Machbarkeitsstudie zur CNN-basierten Identifikation und TICI-Klassifizierung zerebraler ischämischer Infarkte in DSA-Daten
Nielsen, M., Waldmann, M., Frölich, A., Fiehler, J. & Werner, R., 07.02.2019, Bildverarbeitung für die Medizin 2019: Algorithmen – Systeme – Anwendungen. Proceedings des Workshops vom 17. bis 19. März 2019 in Lübeck. 1 ed. Springer Vieweg, p. 200-205 6 p. (Informatik aktuell).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Radiomics of Brain MRI: Utility in Prediction of Metastatic Tumor Type
Kniep, H. C., Madesta, F., Schneider, T., Hanning, U., Schönfeld, M. H., Schön, G., Fiehler, J., Gauer, T., Werner, R. & Gellissen, S., 02.2019, In: RADIOLOGY. 290, 2, p. 479-487 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Combining Good Old Random Forest and DeepLabv3+ for ISLES 2018 CT-Based Stroke Segmentation
Böhme, L., Madesta, F., Sentker, T. & Werner, R., 26.01.2019, Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries. 1 ed. Springer, p. 335-342 8 p. (Lecture Notes in Computer Science; vol. 11383).Research output: SCORING: Contribution to book/anthology › Conference contribution - Article for conference › Research › peer-review