Dr. rer. nat. ID: 2374632
Malik Alawi
Publications
- 2024
New dienelactone hydrolase from microalgae bacterial community-Antibiofilm activity against fish pathogens and potential applications for aquaculture
Bergmann, L., Balzer Le, S., Hageskal, G., Preuss, L., Han, Y., Astafyeva, Y., Loevenich, S., Emmann, S., Perez-Garcia, P., Indenbirken, D., Katzowitsch, E., Thümmler, F., Alawi, M., Wentzel, A., Streit, W. R. & Krohn, I., 03.01.2024, In: SCI REP-UK. 14, 1, p. 377Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2023
Stenotrophomonas maltophilia affects the gene expression profiles of the major pathogens Pseudomonas aeruginosa and Staphylococcus aureus in an in vitro multispecies biofilm model
Alio, I., Moll, R., Hoffmann, T., Mamat, U., Schaible, U. E., Pappenfort, K., Alawi, M., Schie, M., Thünauer, R., Stamm, J., Rohde, H. & Streit, W. R., 12.12.2023, In: MICROBIOL SPECTR. 11, 6, e0085923.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Complete genome sequence of a Staphylococcus condimenti isolated from a port catheter-associated bloodstream infection
Berneking, L., Büttner, H., Qi, M., Günther, T., Lehnhoff, D., Both, A., Christner, M., Wolters, M., Alawi, M., Aepfelbacher, M. & Rohde, H., 19.10.2023, In: MICROBIOL RESOUR ANN. 12, 10, 3 p., e0043823.Research output: SCORING: Contribution to journal › Short publication › Research › peer-review
Impact of AKT1 on cell invasion and radiosensitivity in a triple negative breast cancer cell line developing brain metastasis
Kempska, J., Oliveira-Ferrer, L., Grottke, A., Qi, M., Alawi, M., Meyer, F., Borgmann, K., Hamester, F., Eylmann, K., Rossberg, M., Smit, D. J., Jücker, M., Laakmann, E., Witzel, I., Schmalfeldt, B., Müller, V. & Legler, K., 06.07.2023, In: FRONT ONCOL. 13, p. 1129682 1129682.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A deep intronic variant in DNM1 in a patient with developmental and epileptic encephalopathy creates a splice acceptor site and affects only transcript variants including exon 10a
Harms, F. L., Weiss, D., Lisfeld, J., Alawi, M. & Kutsche, K., 07.2023, In: NEUROGENETICS. 24, 3, p. 171-180 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Preclinical patient-derived modeling of castration-resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease
Elsesy, M. E., Oh-Hohenhorst, S. J., Oing, C., Eckhardt, A., Burdak-Rothkamm, S., Alawi, M., Müller, C., Schüller, U., Maurer, T., von Amsberg, G., Petersen, C., Rothkamm, K. & Mansour, W. Y., 06.2023, In: MOL ONCOL. 17, 6, p. 1129-1147 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
INPP4A-related genetic and phenotypic spectrum and functional relevance of subcellular targeting of INPP4A isoforms
Hecher, L., Harms, F. L., Lisfeld, J., Alawi, M., Denecke, J. & Kutsche, K., 04.2023, In: NEUROGENETICS. 24, 2, p. 79-93 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome-1 in two new patients with the same homozygous TMCO1 variant and review of the literature
Abdelrazek, I. M., Holling, T., Harms, F. L., Alawi, M., Omar, T., Abdalla, E. & Kutsche, K., 03.2023, In: EUR J MED GENET. 66, 3, p. 104715Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Midgut Volvulus Adds a Murine, Neutrophil-Driven Model of Septic Condition to the Experimental Toolbox
Elrod, J., Kiwit, A., Lenz, M., Rohde, H., Börnigen, D., Alawi, M., Mohr, C., Pagerols Raluy, L., Trochimiuk, M., Knopf, J., Reinshagen, K., Herrmann, M. & Boettcher, M., 19.01.2023, In: CELLS-BASEL. 12, 3, 366.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Murine scald models characterize the role of neutrophils and neutrophil extracellular traps in severe burns
Elrod, J., Lenz, M., Kiwit, A., Armbrust, L., Schönfeld, L., Reinshagen, K., Pagerols Raluy, L., Mohr, C., Saygi, C., Alawi, M., Rohde, H., Herrmann, M. & Boettcher, M., 2023, In: FRONT IMMUNOL. 14, p. 1113948Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Diagnostic potential of extracellular vesicles in meningioma patients
Ricklefs, F. L., Maire, C. L., Wollmann, K., Dührsen, L., Fita, K. D., Sahm, F., Herold-Mende, C., von Deimling, A., Kolbe, K., Holz, M., Bergmann, L., Fuh, M. M., Schlüter, H., Alawi, M., Reimer, R., Sven, P., Glatzel, M., Westphal, M. & Lamszus, K., 01.12.2022, In: NEURO-ONCOLOGY. 24, 12, p. 2078-2090 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer
Amsberg, G. V., Zilles, M., Mansour, W., Gild, P., Alsdorf, W., Kaune, M., Böckelmann, L. C., Hauschild, J., Krisp, C., Rohlfing, T., Saygi, C., Alawi, M., Zielinski, A., Langebrake, C., Su, X., Perner, S., Tilki, D., Schluter, H., Graefen, M., Dyshlovoy, S. & Bokemeyer, C., 29.11.2022, In: INT J MOL SCI. 23, 23, 14948.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comprehensive profiling of myxopapillary ependymomas identifies a distinct molecular subtype with relapsing disease
Bockmayr, M., Harnisch, K., Pohl, L. C., Schweizer, L., Mohme, T., Körner, M., Alawi, M., Suwala, A. K., Dorostkar, M. M., Monoranu, C. M., Hasselblatt, M., Wefers, A. K., Capper, D., Hench, J., Frank, S., Richardson, T. E., Tran, I., Liu, E., Snuderl, M., Engertsberger, L., Benesch, M., von Deimling, A., Obrecht, D., Mynarek, M., Rutkowski, S., Glatzel, M., Neumann, J. E. & Schüller, U., 03.10.2022, In: NEURO-ONCOLOGY. 24, 10, p. 1689-1699 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of IG-MYC-breakpoints and their application for quantitative minimal disease monitoring in high-risk pediatric Burkitt-lymphoma and -leukemia
Möker, P., Zur Stadt, U., Zimmermann, M., Alawi, M., Mueller, S., Finger, J., Knörr, F., Riquelme, A., Oschlies, I., Klapper, W., Bradtke, J., Burkhardt, B., Woessmann, W. & Damm-Welk, C., 09.2022, In: LEUKEMIA. 36, 9, p. 2343-2346 4 p.Research output: SCORING: Contribution to journal › Letter › Research
Microalgae and Bacteria Interaction-Evidence for Division of Diligence in the Alga Microbiota
Astafyeva, Y., Gurschke, M., Qi, M., Bergmann, L., Indenbirken, D., de Grahl, I., Katzowitsch, E., Reumann, S., Hanelt, D., Alawi, M., Streit, W. R. & Krohn, I., 31.08.2022, In: MICROBIOL SPECTR. 10, 4, e0063322.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinically Relevant KCNQ1 Variants Causing KCNQ1-KCNE2 Gain-of-Function Affect the Ca2+ Sensitivity of the Channel
Bauer, C. K., Holling, T., Horn, D., Laço, M. N., Abdalla, E., Omar, O. M., Alawi, M. & Kutsche, K., 26.08.2022, In: INT J MOL SCI. 23, 17, 9690.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice
Schepanski, S., Chini, M., Sternemann, V., Urbschat, C., Thiele, K., Sun, T., Zhao, Y., Poburski, M., Woestemeier, A., Thieme, M-T., Zazara, D. E., Alawi, M., Fischer, N., Heeren, J., Vladimirov, N., Woehler, A., Puelles, V. G., Bonn, S., Gagliani, N., Hanganu-Opatz, I. L. & Arck, P. C., 05.08.2022, In: NAT COMMUN. 13, 1, 4571.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cardiofacioneurodevelopmental syndrome: Report of a novel patient and expansion of the phenotype
Abdalla, E., Alawi, M., Meinecke, P., Kutsche, K. & Harms, F. L., 08.2022, In: AM J MED GENET A. 188, 8, p. 2448-2453 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content with potential relevance to inflammation and recovery processes
Bub, A., Brenna, S., Alawi, M., Kügler, P., Gui, Y., Kretz, O., Altmeppen, H., Magnus, T. & Puig, B., 31.05.2022, In: CELL MOL LIFE SCI. 79, 6, p. 329 329.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biallelic FRA10AC1 variants cause a neurodevelopmental disorder with growth retardation
von Elsner, L., Chai, G., Schneeberger, P. E., Harms, F. L., Casar, C., Qi, M., Alawi, M., Abdel-Salam, G. M. H., Zaki, M. S., Arndt, F., Yang, X., Stanley, V., Hempel, M., Gleeson, J. G. & Kutsche, K., 24.05.2022, In: BRAIN. 145, 4, p. 1551-1563 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Novel biallelic variants expand the SLC5A6-related phenotypic spectrum
Holling, T., Nampoothiri, S., Tarhan, B., Schneeberger, P. E., Vinayan, K. P., Yesodharan, D., Roy, A. G., Radhakrishnan, P., Alawi, M., Rhodes, L., Girisha, K. M., Kang, P. B. & Kutsche, K., 04.2022, In: EUR J HUM GENET. 30, 4, p. 439-449 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2021
Transcriptome Analysis in Vulvar Squamous Cell Cancer
Prieske, K., Alawi, M., Jaeger, A., Wankner, M. C., Eylmann, K., Reuter, S., Lebok, P., Burandt, E., Blessin, N. C., Schmalfeldt, B., Prieske, K., Joosse, S. A. & Woelber, L., 19.12.2021, In: CANCERS. 13, 24, 6372.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Vertically transferred maternal immune cells promote neonatal immunity against early life infections
Stelzer, I., Urbschat, C., Schepanski, S., Thiele, K., Triviai, I., Wieczorek, A., Alawi, M., Ohnezeit, D., Kottlau, J., Huang, J., Fischer, N., Mittrücker, H-W., Solano, M. E., Fehse, B., Diemert, A., Stahl, F. & Arck, P., 04.08.2021, In: NAT COMMUN. 12, 1, p. 4706Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice
Deuse, T., Tediashvili, G., Hu, X., Gravina, A., Tamenang, A., Wang, D., Connolly, A., Mueller, C., Mallavia, B., Looney, M. R., Alawi, M., Lanier, L. L. & Schrepfer, S., 13.07.2021, In: P NATL ACAD SCI USA. 118, 28, e2022091118.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biallelic variants in VPS50 cause a neurodevelopmental disorder with neonatal cholestasis
Schneeberger, P. E., Nampoothiri, S., Holling, T., Yesodharan, D., Alawi, M., Knisely, A. S., Müller, T., Plecko, B., Janecke, A. R. & Kutsche, K., 26.05.2021, In: BRAIN. 2021, awab206Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The SIRPα-CD47 immune checkpoint in NK cells
Deuse, T., Hu, X., Agbor-Enoh, S., Jang, M. K., Alawi, M., Saygi, C., Gravina, A., Tediashvili, G., Nguyen, V. Q., Liu, Y., Valantine, H., Lanier, L. L. & Schrepfer, S., 01.03.2021, In: J EXP MED. 218, 3, e20200839.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distinct clonal lineages and within-host diversification shape invasive Staphylococcus epidermidis populations
Both, A., Huang, J., Qi, M., Lausmann, C., Weißelberg, S., Büttner, H., Lezius, S., Failla, A. V., Christner, M., Stegger, M., Gehrke, T., Baig, S., Citak, M., Alawi, M., Aepfelbacher, M. & Rohde, H., 02.2021, In: PLOS PATHOG. 17, 2, p. e1009304Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deep (Meta)genomics and (Meta)transcriptome Analyses of Fungal and Bacteria Consortia From Aircraft Tanks and Kerosene Identify Key Genes in Fuel and Tank Corrosion
Krohn, I., Bergmann, L., Qi, M., Indenbirken, D., Han, Y., Perez-Garcia, P., Katzowitsch, E., Hägele, B., Lübcke, T., Siry, C., Riemann, R., Alawi, M. & Streit, W. R., 2021, In: FRONT MICROBIOL. 12, 722259.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Bi-allelic Pathogenic Variants in HS2ST1 Cause a Syndrome Characterized by Developmental Delay and Corpus Callosum, Skeletal, and Renal Abnormalities
Schneeberger, P. E., von Elsner, L., Barker, E. L., Meinecke, P., Marquardt, I., Alawi, M., Steindl, K., Joset, P., Rauch, A., Zwijnenburg, P. J. G., Weiss, M. M., Merry, C. L. R. & Kutsche, K., 03.12.2020, In: AM J HUM GENET. 107, 6, p. 1044-1061 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Differential regulation of extracellular matrix proteins in three recurrent liver metastases of a single patient with colorectal cancer
Voß, H., Wurlitzer, M., Smit, D. J., Ewald, F., Alawi, M., Spohn, M., Indenbirken, D., Omidi, M., David, K., Juhl, H., Simon, R., Sauter, G., Fischer, L., Izbicki, J. R., Molloy, M. P., Nashan, B., Schlüter, H. & Jücker, M., 12.2020, In: CLIN EXP METASTAS. 37, 6, p. 649-656 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deep amoA amplicon sequencing reveals community partitioning within ammonia-oxidizing bacteria in the environmentally dynamic estuary of the River Elbe
Malinowski, M., Alawi, M., Krohn, I., Ruff, S., Indenbirken, D., Alawi, M., Karrasch, M., Lüschow, R., Streit, W. R., Timmermann, G. & Pommerening-Röser, A., 13.10.2020, In: SCI REP-UK. 10, 1, 17165.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Glioma escape signature and clonal development under immune pressure
Maire, C. L., Mohme, M., Bockmayr, M., Fita, K. D., Riecken, K., Börnigen, D., Alawi, M., Failla, A. V., Kolbe, K., Zapf, S., Holz, M., Neumann, K., Dührsen, L., Lange, T., Fehse, B., Westphal, M. & Lamszus, K., 01.10.2020, In: J CLIN INVEST. 130, 10, p. 5257-5271 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biallelic loss-of-function variants in TBC1D2B cause a neurodevelopmental disorder with seizures and gingival overgrowth
Harms, F. L., Parthasarathy, P., Zorndt, D., Alawi, M., Fuchs, S., Halliday, B. J., McKeown, C., Sampaio, H., Radhakrishnan, N., Radhakrishnan, S. K., Gorce, M., Navet, B., Ziegler, A., Sachdev, R., Robertson, S. P., Nampoothiri, S. & Kutsche, K., 09.2020, In: HUM MUTAT. 41, 9, p. 1645-1661 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Exome sequencing in 38 patients with intracranial aneurysms and subarachnoid hemorrhage
Sauvigny, T., Alawi, M., Krause, L., Renner, S., Spohn, M., Busch, A., Kolbe, V., Altmüller, J., Löscher, B-S., Franke, A., Brockmann, C., Lieb, W., Westphal, M., Schmidt, N. O., Regelsberger, J. & Rosenberger, G., 09.2020, In: J NEUROL. 267, 9, p. 2533-2545 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genomic characterization of vulvar squamous cell carcinoma
Prieske, K., Alawi, M., Oliveira-Ferrer, L., Jaeger, A., Eylmann, K., Burandt, E., Schmalfeldt, B., Joosse, S. A. & Woelber, L., 09.2020, In: GYNECOL ONCOL. 158, 3, p. 547-554 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biallelic MADD variants cause a phenotypic spectrum ranging from developmental delay to a multisystem disorder
Schneeberger, P. E., Kortüm, F., Korenke, G. C., Alawi, M., Santer, R., Woidy, M., Buhas, D., Fox, S., Juusola, J., Alfadhel, M., Webb, B. D., Coci, E. G., Abou Jamra, R., Siekmeyer, M., Biskup, S., Heller, C., Maier, E. M., Javaher-Haghighi, P., Bedeschi, M. F., Ajmone, P. F., Iascone, M., Peeters, H., Ballon, K., Jaeken, J., Rodríguez Alonso, A., Palomares-Bralo, M., Santos-Simarro, F., Meuwissen, M. E. C., Beysen, D., Kooy, R. F., Houlden, H., Murphy, D., Doosti, M., Karimiani, E. G., Mojarrad, M., Maroofian, R., Noskova, L., Kmoch, S., Honzik, T., Cope, H., Sanchez-Valle, A., Undiagnosed Diseases Network, Gelb, B. D., Kurth, I., Hempel, M. & Kutsche, K., 01.08.2020, In: BRAIN. 143, 8, p. 2437-2453 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms
Czech-Sioli, M., Günther, T., Therre, M., Spohn, M., Indenbirken, D., Theiss, J., Riethdorf, S., Qi, M., Alawi, M., Wülbeck, C., Fernandez-Cuesta, I., Esmek, F., Becker, J. C., Grundhoff, A. & Fischer, N., 08.2020, In: PLOS PATHOG. 16, 8, e1008562.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clonal Evolution after Allogeneic Hematopoietic Stem Cell Transplantation
Christopeit, M., Badbaran, A., Alawi, M., Flach, J., Fehse, B. & Kröger, N., 07.2020, In: BIOL BLOOD MARROW TR. 26, 7, p. e167-e170Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Draft Genome Sequence of the Green Alga Scenedesmus acuminatus SAG 38.81
Astafyeva, Y., Alawi, M., Indenbirken, D., Danso, D., Grundhoff, A., Hanelt, D., Streit, W. R. & Krohn, I., 11.06.2020, In: MICROBIOL RESOUR ANN. 9, 24, e01278-19.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
A prenatally disrupted airway epithelium orchestrates the fetal origin of asthma in mice
Zazara-Giannou, D., Wegmann, M., Giannou, A. D., Hierweger, A. M., Alawi, M., Thiele, K., Huber, S., Pincus, M., Muntau, A. C., Solano, M. E. & Arck, P. C., 06.2020, In: J ALLERGY CLIN IMMUN. 145, 6, p. 1641-1654 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection
Thiele, S., Stanelle-Bertram, S., Beck, S., Kouassi, N. M., Zickler, M., Müller, M., Tuku, B., Resa-Infante, P., van Riel, D., Alawi, M., Günther, T., Rother, F., Hügel, S., Reimering, S., McHardy, A., Grundhoff, A., Brune, W., Osterhaus, A., Bader, M., Hartmann, E. & Gabriel, G., 21.04.2020, In: CELL REP. 31, 3, 107549.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape
Mohme, M., Maire, C. L., Schliffke, S., Joosse, S. A., Alawi, M., Matschke, J., Schüller, U., Dierlamm, J., Martens, T., Pantel, K., Riethdorf, S., Lamszus, K. & Westphal, M., 09.03.2020, In: ACTA NEUROPATHOL COM. 8, 1, 28.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The landscape of viral associations in human cancers
Zapatka, M., Borozan, I., Brewer, D. S., Iskar, M., Grundhoff, A., Alawi, M., Desai, N., Sültmann, H., Moch, H., Cooper, C. S., Eils, R., Ferretti, V., Lichter, P. & PCAWG Pathogens, 03.2020, In: NAT GENET. 52, 3, p. 320-330 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Extremophilic nitrite-oxidizing Chloroflexi from Yellowstone hot springs
Spieck, E., Spohn, M., Wendt, K., Bock, E., Shively, J., Frank, J., Indenbirken, D., Alawi, M., Lücker, S. & Hüpeden, J., 02.2020, In: ISME J. 14, 2, p. 364-379 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pan-cancer analysis of whole genomes
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, 02.2020, In: NATURE. 578, 7793, p. 82-93 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Characterization of novel, recurrent genomic rearrangements as sensitive MRD targets in childhood B-cell precursor ALL
Zur Stadt, U., Alawi, M., Adao, M., Indenbirken, D., Escherich, G. & Horstmann, M. A., 29.11.2019, In: BLOOD CANCER J. 9, 12, p. 96Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DAMIAN an open source bioinformatics tool for fast, systematic and cohort based analysis of microorganisms in diagnostic samples
Alawi, M., Burkhardt, L., Indenbirken, D., Reumann, K., Christopeit, M., Kröger, N., Lütgehetmann, M., Aepfelbacher, M., Fischer, N. & Grundhoff, A., 14.11.2019, In: SCI REP-UK. 9, 1, p. 16841Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biallelic and De Novo Variants in DONSON Reveal a Clinical Spectrum of Cell Cycle-opathies with Microcephaly, Dwarfism and Skeletal Abnormalities
Karaca, E., Posey, J. E., Bostwick, B., Liu, P., Gezdirici, A., Yesil, G., Coban Akdemir, Z., Bayram, Y., Harms, F. L., Meinecke, P., Alawi, M., Bacino, C. A., Sutton, V. R., Kortüm, F. & Lupski, J. R., 10.2019, In: AM J MED GENET A. 179, 10, p. 2056-2066 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Alternative interaction sites in the influenza A virus nucleoprotein mediate viral escape from the importin-α7 mediated nuclear import pathway
Resa-Infante, P., Bonet, J., Thiele, S., Alawi, M., Stanelle-Bertram, S., Tuku, B., Beck, S., Oliva, B. & Gabriel, G., 09.2019, In: FEBS J. 286, 17, p. 3374-3388 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Next-generation sequencing of 32 genes associated with hereditary aortopathies and related disorders of connective tissue in a cohort of 199 patients
Renner, S., Schüler, H., Alawi, M., Kolbe, V., Rybczynski, M., Woitschach, R., Sheikhzadeh, S., Stark, V. C., Olfe, J., Roser, E., Seggewies, F. S., Mahlmann, A., Hempel, M., Hartmann, M. J., Hillebrand, M., Wieczorek, D., Volk, A. E., Kloth, K., Koch-Hogrebe, M., Abou Jamra, R., Mitter, D., Altmüller, J., Wey-Fabrizius, A., Petersen, C., Rau, I., Borck, G., Kubisch, C., Mir, T. S., von Kodolitsch, Y., Kutsche, K. & Rosenberger, G., 08.2019, In: GENET MED. 21, 8, p. 1832-1841 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair
Seoane, M., Buhs, S., Iglesias, P., Strauss, J., Puller, A-C., Müller, J., Gerull, H., Feldhaus, S., Alawi, M., Brandner, J. M., Eggert, D., Du, J., Thomale, J., Wild, P. J., Zimmermann, M., Sternsdorf, T., Schumacher, U., Nollau, P., Fisher, D. E. & Horstmann, M. A., 05.2019, In: ONCOGENE. 38, 19, p. 3616-3635 20 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
T-lymphocyte-specific knockout of IKK-2 or NEMO induces T17 cells in an experimental nephrotoxic nephritis mouse model
Guo, L., Huang, J., Chen, M., Piotrowski, E., Song, N., Zahner, G., Paust, H-J., Alawi, M., Geffers, R. & Thaiss, F., 02.2019, In: FASEB J. 33, 2, p. 2359-2371 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease
Neelagandan, N., Gonnella, G., Dang, S., Janiesch, P. C., Miller, K. K., Küchler, K., Marques, R. F., Indenbirken, D., Alawi, M., Grundhoff, A., Kurtz, S. & Duncan, K. E., 10.01.2019, In: NUCLEIC ACIDS RES. 47, 1, p. 341-361 21 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Coinheritance of biallelic SLURP1 and SLC39A4 mutations cause a severe genodermatosis with skin peeling and hair loss all over the body
Harms, F. L., Nampoothiri, S., Kortüm, F., Thomas, J., Panicker, V. V., Alawi, M., Altmüller, J., Yesodharan, D. & Kutsche, K., 11.2018, In: BRIT J DERMATOL. 179, 5, p. 1192-1194 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Reply: ATAD1 encephalopathy and stiff baby syndrome: a recognizable clinical presentation
Piard, J., Essien Umanah, G. K., Harms, F. L., Abalde-Atristain, L., Amram, D., Chang, M., Chen, R., Alawi, M., Salpietro, V., Rees, M. I., Chung, S-K., Houlden, H., Verloes, A., Dawson, T. M., Dawson, V. L., Van Maldergem, L. & Kutsche, K., 01.06.2018, In: BRAIN. 141, 6, p. e50Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Clinical and genetic spectrum of AMPD2-related pontocerebellar hypoplasia type 9
Kortüm, F., Jamra, R. A., Alawi, M., Berry, S. A., Borck, G., Helbig, K. L., Tang, S., Huhle, D., Korenke, G. C., Hebbar, M., Shukla, A., Girisha, K. M., Steinlin, M., Waldmeier-Wilhelm, S., Montomoli, M., Guerrini, R., Lemke, J. R. & Kutsche, K., 05.2018, In: EUR J HUM GENET. 26, 5, p. 695-708 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A homozygous ATAD1 mutation impairs postsynaptic AMPA receptor trafficking and causes a lethal encephalopathy
Piard, J., Umanah, G. K. E., Harms, F. L., Abalde-Atristain, L., Amram, D., Chang, M., Chen, R., Alawi, M., Salpietro, V., Rees, M. I., Chung, S-K., Houlden, H., Verloes, A., Dawson, T. M., Dawson, V. L., Van Maldergem, L. & Kutsche, K., 01.03.2018, In: BRAIN. 141, 3, p. 651-661 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Elsahy-Waters syndrome is caused by biallelic mutations in CDH11
Harms, F. L., Nampoothiri, S., Anazi, S., Yesodharan, D., Alawi, M., Kutsche, K. & Alkuraya, F. S., 02.2018, In: AM J MED GENET A. 176, 2, p. 477-482 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The novel RAF1 mutation p.(Gly361Ala) located outside the kinase domain of the CR3 region in two patients with Noonan syndrome, including one with a rare brain tumor
Harms, F. L., Alawi, M., Amor, D. J., Tan, T. Y., Cuturilo, G., Lissewski, C., Brinkmann, J., Schanze, D., Kutsche, K. & Zenker, M., 02.2018, In: AM J MED GENET A. 176, 2, p. 470-476 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Long-term CD38 saturation by daratumumab interferes with diagnostic myeloma cell detection
Oberle, A., Brandt, A., Alawi, M., Langebrake, C., Janjetovic, S., Wolschke, C., Schütze, K., Bannas, P., Kröger, N., Koch-Nolte, F., Bokemeyer, C. & Binder, M., 09.2017, In: HAEMATOLOGICA. 102, 9, p. e368-e370Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells
Babayan, A., Alawi, M., Gormley, M., Müller, V., Wikman, H., McMullin, R. P., Smirnov, D. A., Li, W., Geffken, M., Pantel, K. & Joosse, S. A., 22.08.2017, In: ONCOTARGET. 8, 34, p. 56066-56080 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Optimization of design and production strategies for novel adeno-associated viral display peptide libraries
Körbelin, J., Hunger, A., Alawi, M., Sieber, T., Binder, M. & Trepel, M., 08.2017, In: GENE THER. 24, 8, p. 470-481Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Recovery of the first full-length genome sequence of a parapoxvirus directly from a clinical sample
Günther, T., Haas, L., Alawi, M., Wohlsein, P., Marks, J., Grundhoff, A., Becher, P. & Fischer, N., 16.06.2017, In: SCI REP-UK. 7, 1, p. 3734Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monitoring multiple myeloma by next-generation sequencing of V(D)J rearrangements from circulating myeloma cells and cell-free myeloma DNA
Oberle, A., Brandt, A., Voigtländer, M., Thiele, B., Radloff, J., Schulenkorf, A., Alawi, M., Akyüz, N., März, M., Ford, C. T., Krohn-Grimberghe, A. & Binder, M., 06.2017, In: HAEMATOLOGICA. 102, 6, p. 1105-1111Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells
Nagarajan, S., Bedi, U., Budida, A., Hamdan, F. H., Mishra, V. K., Najafova, Z., Xie, W., Alawi, M., Indenbirken, D., Knapp, S., Chiang, C-M., Grundhoff, A., Kari, V., Scheel, C. H., Wegwitz, F. & Johnsen, S. A., 07.04.2017, In: NUCLEIC ACIDS RES. 45, 6, p. 3130-3145 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pregnancy-Related Immune Adaptation Promotes the Emergence of Highly Virulent H1N1 Influenza Virus Strains in Allogenically Pregnant Mice
Engels, G., Hierweger, A. M., Hoffmann, J., Thieme, R., Thiele, S., Bertram, S., Dreier, C., Resa-Infante, P., Jacobsen, H., Thiele, K., Alawi, M., Indenbirken, D., Grundhoff, A., Siebels, S., Fischer, N., Stojanovska, V., Muzzio, D., Jensen, F., Karimi, K., Mittrücker, H-W., Arck, P. C. & Gabriel, G., 08.03.2017, In: CELL HOST MICROBE. 21, 3, p. 321-333 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus
Coronado, L., Liniger, M., Muñoz-González, S., Postel, A., Pérez, L. J., Pérez-Simó, M., Perera, C. L., Frías-Lepoureau, M. T., Rosell, R., Grundhoff, A., Indenbirken, D., Alawi, M., Fischer, N., Becher, P., Ruggli, N. & Ganges, L., 03.2017, In: VET MICROBIOL. 201, p. 103-112 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutational landscape reflects the biological continuum of plasma cell dyscrasias
Rossi, A., Voigtländer, M., Janjetovic, S., Thiele, B., Alawi, M., März, M., Brandt, A., Hansen, T., Radloff, J., Schön, G., Hegenbart, U., Schönland, S., Langer, C., Bokemeyer, C. & Binder, M., 24.02.2017, In: BLOOD CANCER J. 7, 2, p. e537Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutations in EBF3 Disturb Transcriptional Profiles and Cause Intellectual Disability, Ataxia, and Facial Dysmorphism
Harms, F. L., Girisha, K. M., Hardigan, A. A., Kortüm, F., Shukla, A., Alawi, M., Dalal, A., Brady, L., Tarnopolsky, M., Bird, L. M., Ceulemans, S., Bebin, M., Bowling, K. M., Hiatt, S. M., Lose, E. J., Primiano, M., Chung, W. K., Juusola, J., Akdemir, Z. C., Bainbridge, M., Charng, W-L., Drummond-Borg, M., Eldomery, M. K., El-Hattab, A. W., Saleh, M. A. M., Bézieau, S., Cogné, B., Isidor, B., Küry, S., Lupski, J. R., Myers, R. M., Cooper, G. M. & Kutsche, K., 05.01.2017, In: AM J HUM GENET. 100, 1, p. 117-127Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Acute Liver Failure Meets SOPH Syndrome: A Case Report on an Intermediate Phenotype
Kortüm, F., Marquardt, I., Alawi, M., Korenke, G. C., Spranger, S., Meinecke, P. & Kutsche, K., 01.2017, In: PEDIATRICS. 139, 1, p. pii: e20160550Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Insights into Microalga and Bacteria Interactions of Selected Phycosphere Biofilms Using Metagenomic, Transcriptomic, and Proteomic Approaches
Krohn-Molt, I., Alawi, M., Förstner, K. U., Wiegandt, A., Burkhardt, L., Indenbirken, D., Thieß, M., Grundhoff, A., Kehr, J., Tholey, A. & Streit, W. R., 2017, In: FRONT MICROBIOL. 8, p. 1941Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Versatility of Biofilm Matrix Molecules in Staphylococcus epidermidis Clinical Isolates and Importance of Polysaccharide Intercellular Adhesin Expression during High Shear Stress
Schaeffer, C. R., Hoang, T-M. N., Sudbeck, C. M., Alawi, M., Tolo, I. E., Robinson, D. A., Horswill, A. R., Rohde, H. & Fey, P. D., 18.10.2016, In: MSPHERE. 1, 5, p. e00165-16.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype
Shashi, V., Pena, L. D. M., Kim, K., Burton, B., Hempel, M., Schoch, K., Walkiewicz, M., McLaughlin, H. M., Cho, M., Stong, N., Hickey, S. E., Shuss, C. M., Undiagnosed Diseases Network, Freemark, M. S., Bellet, J. S., Keels, M. A., Bonner, M. J., El-Dairi, M., Butler, M., Kranz, P. G., Stumpel, C. T. R. M., Klinkenberg, S., Oberndorff, K., Alawi, M., Santer, R., Petrovski, S., Kuismin, O., Korpi-Heikkilä, S., Pietilainen, O., Aarno, P., Kurki, M. I., Hoischen, A., Need, A. C., Goldstein, D. B. & Kortüm, F., 06.10.2016, In: AM J HUM GENET. 99, 4, p. 991-999 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles
Fischer, S., Cornils, K., Speiseder, T., Badbaran, A., Reimer, R., Indenbirken, D., Grundhoff, A., Brunswig-Spickenheier, B., Alawi, M. & Lange, C., 30.09.2016, In: PLOS ONE. 11, 9, p. e0163665Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Correlation of somatic mutations with outcome after FLAMSA-busulfan sequential conditioning and allogeneic stem cell transplantation in patients with MDS
Christopeit, M., Badbaran, A., Alawi, M., Zabelina, T., Zeck, G., Wolschke, C., Ayuketang, F. A. & Kröger, N., 01.09.2016, In: EUR J HAEMATOL. 97, 3, p. 288-96Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel multiple joint dislocation syndrome associated with a homozygous nonsense variant in the EXOC6B gene
Girisha, K. M., Kortüm, F., Shah, H., Alawi, M., Dalal, A., Bhavani, G. S. & Kutsche, K., 01.08.2016, In: EUR J HUM GENET. 24, 8, p. 1206-10Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homozygous HOXB1 loss-of-function mutation in a large family with hereditary congenital facial paresis
Vogel, M., Velleuer, E., Schmidt-Jiménez, L. F., Mayatepek, E., Borkhardt, A., Alawi, M., Kutsche, K. & Kortüm, F., 07.2016, In: AM J MED GENET A. 170, 7, p. 1813-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pegivirus Infection in Domestic Pigs, Germany
Baechlein, C., Grundhoff, A., Fischer, N., Alawi, M., Hoeltig, D., Waldmann, K-H. & Becher, P., 07.2016, In: EMERG INFECT DIS. 22, 7, p. 1312-4 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Runx1 downregulates stem cell and megakaryocytic transcription programs that support niche interactions
Behrens, K., Triviai, I., Schwieger, M., Tekin, N., Alawi, M., Spohn, M., Indenbirken, D., Ziegler, M., Müller, U., Alexander, W. S. & Stocking, C., 30.06.2016, In: BLOOD. 127, 26, p. 3369-81 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A transplant “immunome” screening platform defines a targetable epitope fingerprint of multiple myeloma
Schieferdecker, A., Oberle, A., Thiele, B., Hofmann, F., Göthel, M., Miethe, S., Hust, M., Braig, F., Voigt, M., Pein, U-M., Nolte, F., Haag, F., Alawi, M., Indenbirken, D., Grundhoff, A., Bokemeyer, C., Bacher, U., Kröger, N. & Binder, M., 23.06.2016, In: BLOOD. 127, 25, p. 3202-14Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells
Berneking, L., Schnapp, M., Rumm, A., Trasak, C., Ruckdeschel, K., Alawi, M., Grundhoff, A., Kikhney, A. G., Nolte, F., Buck, F., Perbandt, M., Betzel, C., Svergun, D. I., Hentschke, M. & Aepfelbacher, M., 13.06.2016, In: PLOS PATHOG. 12, 6, p. e1005660Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pulmonary Targeting of Adeno-associated Viral Vectors by Next-generation Sequencing-guided Screening of Random Capsid Displayed Peptide Libraries
Körbelin, J., Sieber, T., Michelfelder, S., Lunding, L., Spies, E., Hunger, A., Alawi, M., Rapti, K., Indenbirken, D., Müller, O. J., Pasqualini, R., Arap, W., Kleinschmidt, J. A. & Trepel, M., 06.2016, In: MOL THER. 24, 6, p. 1050-61Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional dissection of an alternatively spliced herpesvirus gene by splice site mutagenesis
Schommartz, T., Loroch, S., Alawi, M., Grundhoff, A., Sickmann, A. & Brune, W., 14.04.2016, In: J VIROL. 90, 9, p. 4626-36Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Rapid Capture Next-Generation Sequencing in Clinical Diagnostics of Kinase Pathway Aberrations in B-Cell Precursor ALL
Stadt, U. Z., Escherich, G., Indenbirken, D., Alawi, M., Adao, M. & Horstmann, M. A., 23.03.2016, In: PEDIATR BLOOD CANCER. 63, 7, p. 1283-6Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Essential control of early B-cell development by Mef2 transcription factors
Herglotz, J., Unrau, L., Hauschildt, F., Fischer, M., Kriebitzsch, N., Alawi, M., Indenbirken, D., Spohn, M., Müller, U., Ziegler, M., Schuh, W., Jäck, H-M. & Stocking, C., 04.02.2016, In: BLOOD. 127, 5, p. 572-81 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deep metagenome and metatranscriptome analyses of microbial communities affiliated with an industrial biogas fermenter, a cow rumen, and elephant feces reveal major differences in carbohydrate hydrolysis strategies
Güllert, S., Fischer, M. A., Turaev, D., Noebauer, B., Ilmberger, N., Wemheuer, B., Alawi, M., Rattei, T., Daniel, R., Schmitz, R. A., Grundhoff, A. & Streit, W. R., 2016, In: BIOTECHNOL BIOFUELS. 9, p. 121Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Presence of atypical porcine pestivirus (APPV) genomes in newborn piglets correlates with congenital tremor
Postel, A., Hansmann, F., Baechlein, C., Fischer, N., Alawi, M., Grundhoff, A., Derking, S., Tenhündfeld, J., Pfankuche, V. M., Herder, V., Baumgärtner, W., Wendt, M. & Becher, P., 2016, In: SCI REP-UK. 6, p. 27735Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Emergence of daptomycin non-susceptibility in colonizing vancomycin-resistant Enterococcus faecium isolates during daptomycin therapy
Lellek, H., Franke, G. C., Ruckert, C., Wolters, M., Wolschke, C., Christner, M., Büttner, H., Alawi, M., Kröger, N. & Rohde, H., 12.09.2015, In: INT J MED MICROBIOL. 305, 8, p. 902-909Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence
Theiss, J. M., Günther, T., Alawi, M., Neumann, F., Tessmer, U., Fischer, N. & Grundhoff, A., 07.2015, In: PLOS PATHOG. 11, 7, p. e1004974Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples
Fischer, N., Indenbirken, D., Meyer, T., Lütgehetmann, M., Lellek, H., Spohn, M., Aepfelbacher, M., Alawi, M. & Grundhoff, A., 07.2015, In: J CLIN MICROBIOL. 53, 7, p. 2238-50 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of a Novel Hepacivirus in Domestic Cattle from Germany
Fischer, N., Baechlein, C., Grundhoff, A., Alawi, M., Indenbirken, D., Postel, A., Baron, A. L., Offinger, J., Becker, K., Beineke, A., Rehage, J. & Becher, P., 07.2015, In: J VIROL. 89, 14, p. 7007-15 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome
Kortüm, F., Caputo, V., Bauer, C. K., Stella, L., Ciolfi, A., Alawi, M., Bocchinfuso, G., Flex, E., Paolacci, S., Dentici, M. L., Grammatico, P., Korenke, G. C., Leuzzi, V., Mowat, D., Nair, L. D. V., Nguyen, T. T. M., Thierry, P., White, S. M., Dallapiccola, B., Pizzuti, A., Campeau, P. M., Tartaglia, M. & Kutsche, K., 01.06.2015, In: NAT GENET. 47, 6, p. 661-7 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer
Braig, F., März, M., Schieferdecker, A., Schulte, A., Voigt, M., Stein, A., Grob, T., Alawi, M., Indenbirken, D., Kriegs, M., Engel, E., Vanhoefer, U., Grundhoff, A., Loges, S., Riecken, K., Fehse, B., Bokemeyer, C. & Binder, M., 20.05.2015, In: ONCOTARGET. 6, 14, p. 12035-47 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mutations in NDUFB11, Encoding a Complex I Component of the Mitochondrial Respiratory Chain, Cause Microphthalmia with Linear Skin Defects Syndrome
van Rahden, V. A., Fernandez-Vizarra, E., Alawi, M., Brand, K., Fellmann, F., Horn, D., Zeviani, M. & Kutsche, K., 02.04.2015, In: AM J HUM GENET. 96, 4, p. 640-50 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deciphering the microRNA signature of pathological cardiac hypertrophy by engineered heart tissue- and sequencing-technology
Hirt, M. N., Werner, T., Indenbirken, D., Alawi, M., Demin, P., Kunze, A-C., Stenzig, J., Starbatty, J., Hansen, A., Fiedler, J., Thum, T. & Eschenhagen, T., 01.04.2015, In: J MOL CELL CARDIOL. 81, p. 1-9 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Close relationship of ruminant pestiviruses and classical Swine Fever virus
Postel, A., Schmeiser, S., Oguzoglu, T. C., Indenbirken, D., Alawi, M., Fischer, N., Grundhoff, A. & Becher, P., 04.2015, In: EMERG INFECT DIS. 21, 4, p. 668-72 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts
Deuse, T., Wang, D., Stubbendorff, M., Itagaki, R., Grabosch, A., Greaves, L. C., Alawi, M., Grünewald, A., Hu, X., Hua, X., Velden, J., Reichenspurner, H., Robbins, R. C., Jaenisch, R., Weissman, I. L. & Schrepfer, S., 08.01.2015, In: CELL STEM CELL. 16, 1, p. 33-38 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
An AP4B1 frameshift mutation in siblings with intellectual disability and spastic tetraplegia further delineates the AP-4 deficiency syndrome
Abdollahpour, H., Alawi, M., Kortüm, F., Beckstette, M., Seemanova, E., Komárek, V., Rosenberger, G. & Kutsche, K., 2015, In: EUR J HUM GENET. 23, 2, p. 256-259Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription
Nagarajan, S., Hossan, T., Alawi, M., Najafova, Z., Indenbirken, D., Bedi, U., Taipaleenmäki, H., Ben-Batalla, I., Scheller, M., Loges, S., Knapp, S., Hesse, E., Chiang, C-M., Grundhoff, A. & Johnsen, S. A., 24.07.2014, In: CELL REP. 8, 2, p. 459-468 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Exom-Sequenzierung zur Identifizierung von Krankheitsgenen für seltene Syndrome: Erfahrungen aus Hamburg
Kortüm, F., Abdollahpour, H., Alawi, M., Korenke, G. C., Seemanova, E., Tinschert, S., Zenker, M., Rosenberger, G. & Kutsche, K., 12.06.2014, In: MED GENET-BERLIN. 26, p. 246-254Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review