ID: 40310

Martin Mynarek

graph of relations

Publications

  1. 2024
  2. Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation

    Neyazi, S., Yamazawa, E., Hack, K., Tanaka, S., Nagae, G., Kresbach, C., Umeda, T., Eckhardt, A., Tatsuno, K., Pohl, L., Hana, T., Bockmayr, M., Kim, P., Dorostkar, M. M., Takami, T., Obrecht, D., Takai, K., Suwala, A. K., Komori, T., Godbole, S., Wefers, A. K., Otani, R., Neumann, J. E., Higuchi, F., Schweizer, L., Nakanishi, Y., Monoranu, C-M., Takami, H., Engertsberger, L., Yamada, K., Ruf, V., Nomura, M., Mohme, T., Mukasa, A., Herms, J., Takayanagi, S., Mynarek, M., Matsuura, R., Lamszus, K., Ishii, K., Kluwe, L., Imai, H., von Deimling, A., Koike, T., Benesch, M., Kushihara, Y., Snuderl, M., Nambu, S., Frank, S., Omura, T., Hagel, C., Kugasawa, K., Mautner, V. F., Ichimura, K., Rutkowski, S., Aburatani, H., Saito, N. & Schüller, U., 24.01.2024, In: ACTA NEUROPATHOL. 147, 1, p. 22

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Child-centredness in paediatric magnetic resonance imaging: Information needs and experiences of children requiring magnetic resonance imaging and their parents

    Inhestern, L., Herrmann, J., Schürmann, J., Meister, R. L., Nawka, M. T., Mynarek, M., Linhart, D. & Bergelt, C., 01.2024, In: CHILD CARE HLTH DEV. 50, 1, p. e13157

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. 2023
  5. Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome

    Kolodziejczak, A. S., Guerrini-Rousseau, L., Planchon, J. M., Ecker, J., Selt, F., Mynarek, M., Obrecht, D., Sill, M., Autry, R. J., Zhao, E., Hirsch, S., Amouyal, E., Dufour, C., Ayrault, O., Torrejon, J., Waszak, S. M., Ramaswamy, V., Pentikainen, V., Demir, H. A., Clifford, S. C., Schwalbe, E. C., Massimi, L., Snuderl, M., Galbraith, K., Karajannis, M. A., Hill, K., Li, B. K., Walsh, M., White, C. L., Redmond, S., Loizos, L., Jakob, M., Kordes, U. R., Schmid, I., Hauer, J., Blattmann, C., Filippidou, M., Piccolo, G., Scheurlen, W., Farrag, A., Grund, K., Sutter, C., Pietsch, T., Frank, S., Schewe, D. M., Malkin, D., Ben-Arush, M., Sehested, A., Wong, T-T., Wu, K-S., Liu, Y-L., Carceller, F., Mueller, S., Stoller, S., Taylor, M. D., Tabori, U., Bouffet, E., Kool, M., Sahm, F., von Deimling, A., Korshunov, A., von Hoff, K., Kratz, C. P., Sturm, D., Jones, D. T. W., Rutkowski, S., van Tilburg, C. M., Witt, O., Bougeard, G., Pajtler, K. W., Pfister, S. M., Bourdeaut, F. & Milde, T., 08.12.2023, In: NEURO-ONCOLOGY. 25, 12, p. 2273-2286 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures

    Schoof, M., Godbole, S., Albert, T. K., Dottermusch, M., Walter, C., Ballast, A., Qin, N., Olivera, M. B., Göbel, C., Neyazi, S., Holdhof, D., Kresbach, C., Peter, L-S., Epplen, G. D., Thaden, V., Spohn, M., Blattner-Johnson, M., Modemann, F., Mynarek, M., Rutkowski, S., Sill, M., Varghese, J., Afflerbach, A-K., Eckhardt, A., Münter, D., Verma, A., Struve, N., Jones, D. T. W., Remke, M., Neumann, J. E., Kerl, K. & Schüller, U., 24.11.2023, In: NAT COMMUN. 14, 1, p. 7717

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Risk prediction in early childhood sonic hedgehog medulloblastoma treated with radiation-avoiding chemotherapy

    Tonn, S., Korshunov, A., Obrecht, D., Sill, M., Spohn, M., von Hoff, K., Milde, T., Pietsch, T., Goschzik, T., Bison, B., Juhnke, B-O., Struve, N., Sturm, D., Sahm, F., Bockmayr, M., Friedrich, C., von Bueren, A. O., Gerber, N. U., Benesch, M., Jones, D. T. W., Kool, M., Wefers, A. K., Schüller, U., Pfister, S. M., Rutkowski, S. & Mynarek, M., 03.08.2023, In: NEURO-ONCOLOGY. 25, 8, p. 1518-1529 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Mitochondrial DNA mutations in Medulloblastoma

    Funke, V. L. E., Sandmann, S., Melcher, V., Seggewiss, J., Horvath, J., Jäger, N., Kool, M., Jones, D. T. W., Pfister, S. M., Milde, T., Rutkowski, S., Mynarek, M., Varghese, J., Sträter, R., Rust, S., Seelhöfer, A., Reunert, J., Fiedler, B., Schüller, U., Marquardt, T. & Kerl, K., 27.07.2023, In: ACTA NEUROPATHOL COM. 11, 1, p. 124

    Research output: SCORING: Contribution to journalCase reportResearchpeer-review

  9. Group-specific cellular metabolism in Medulloblastoma

    Funke, V. L. E., Walter, C., Melcher, V., Wei, L., Sandmann, S., Hotfilder, M., Varghese, J., Jäger, N., Kool, M., Jones, D. T. W., Pfister, S. M., Milde, T., Mynarek, M., Rutkowski, S., Seggewiss, J., Jeising, D., de Faria, F. W., Marquardt, T., Albert, T. K., Schüller, U. & Kerl, K., 05.06.2023, In: J TRANSL MED. 21, 1, p. 363

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes

    Korshunov, A., Okonechnikov, K., Schrimpf, D., Tonn, S., Mynarek, M., Koster, J., Sievers, P., Milde, T., Sahm, F., Jones, D. T. W., von Deimling, A., Pfister, S. M. & Kool, M., 06.2023, In: ACTA NEUROPATHOL. 145, 6, p. 829-842 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Kinder und Jugendliche mit intrakraniellem Ependymom – Empfehlungen der HIT-MED-Studiengruppe der GPOH zur Erstlinientherapie

    Obrecht, D., Mynarek, M., Stickan-Verfürth, M., Bison, B., Schüller, U., Pajtler, K., Hagel, C., Thomale, U-W., Fleischhack, G., Timmermann, B. & Rutkowski, S., 12.05.2023, In: KLIN PADIATR. 235, 3, p. 167-177 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study

    Erker, C., Mynarek, M., Bailey, S., Mazewski, C. M., Baroni, L., Massimino, M., Hukin, J., Aguilera, D., Cappellano, A. M., Ramaswamy, V., Lassaletta, A., Perreault, S., Kline, C. N., Rajagopal, R., Michaiel, G., Zapotocky, M., Santa-Maria Lopez, V., La Madrid, A. M., Cacciotti, C., Sandler, E. S., Hoffman, L. M., Klawinski, D., Khan, S., Salloum, R., Hoppmann, A. L., Larouche, V., Dorris, K., Toledano, H., Gilheeney, S. W., Abdelbaki, M. S., Wilson, B., Tsang, D. S., Knipstein, J., Oren, M. Y., Shah, S., Murray, J. C., Ginn, K. F., Wang, Z. J., Fleischhack, G., Obrecht, D., Tonn, S., Harrod, V. L., Matheson, K., Crooks, B., Strother, D. R., Cohen, K. J., Hansford, J. R., Mueller, S., Margol, A., Gajjar, A., Dhall, G., Finlay, J. L., Northcott, P. A., Rutkowski, S., Clifford, S. C., Robinson, G., Bouffet, E. & Lafay-Cousin, L., 01.04.2023, In: J CLIN ONCOL. 41, 10, p. 1921-1932 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology

    Sturm, D., Capper, D., Andreiuolo, F., Gessi, M., Kölsche, C., Reinhardt, A., Sievers, P., Wefers, A. K., Ebrahimi, A., Suwala, A. K., Gielen, G. H., Sill, M., Schrimpf, D., Stichel, D., Hovestadt, V., Daenekas, B., Rode, A., Hamelmann, S., Previti, C., Jäger, N., Buchhalter, I., Blattner-Johnson, M., Jones, B. C., Warmuth-Metz, M., Bison, B., Grund, K., Sutter, C., Hirsch, S., Dikow, N., Hasselblatt, M., Schüller, U., Gerber, N. U., White, C. L., Buntine, M. K., Kinross, K., Algar, E. M., Hansford, J. R., Gottardo, N. G., Hernáiz Driever, P., Gnekow, A., Witt, O., Müller, H. L., Calaminus, G., Fleischhack, G., Kordes, U., Mynarek, M., Rutkowski, S., Frühwald, M. C., Kramm, C. M., von Deimling, A., Pietsch, T., Sahm, F., Pfister, S. M. & Jones, D. T. W., 04.2023, In: NAT MED. 29, 4, p. 917-926 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells

    Cetin, M. H., Rieckmann, T., Hoffer, K., Riepen, B., Christiansen, S., Gatzemeier, F., Feyerabend, S., Schoof, M., Schüller, U., Petersen, C., Mynarek, M., Rothkamm, K., Kriegs, M. & Struve, N., 29.01.2023, In: RADIAT ONCOL. 18, 1, 19.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level

    Voß, H., Godbole, S., Schlumbohm, S., Schumann, Y., Peng, B., Mynarek, M., Rutkowski, S. J., Dottermusch, M., Dorostkar, M. M., Koshunov, A., Mair, T., Pfister, S. M., Neumann, P., Hartmann, C., Weis, J., Liesche-Starnecker, F., Guan, Y., Schlüter, H., Schüller, U., Krisp, C. & Neumann, J., 09.01.2023, In: bioRxiv. 2023

    Research output: SCORING: Contribution to journalPreprintResearch

  16. Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts

    Mynarek, M., Obrecht, D., Sill, M., Sturm, D., Kloth-Stachnau, K., Selt, F., Ecker, J., von Hoff, K., Juhnke, B-O., Goschzik, T., Pietsch, T., Bockmayr, M., Kool, M., von Deimling, A., Witt, O., Schüller, U., Benesch, M., Gerber, N. U., Sahm, F., Jones, D. T. W., Korshunov, A., Pfister, S. M., Rutkowski, S. & Milde, T., 01.2023, In: ACTA NEUROPATHOL. 145, 1, p. 97-112 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. A multi-institutional retrospective pooled outcome analysis of molecularly annotated pediatric supratentorial ZFTA-fused ependymoma

    Ng, C. H., Obrecht, D., Wells, O., Zapotocky, M., Sumerauer, D., Coltin, H., Khuong-Quang, D-A., Eisenstat, D. D., Kinross, K. M., White, C. L., Algar, E. M., Luck, A., Witt, H., Schüller, U., Mynarek, M., Pietsch, T., Gerber, N. U., Benesch, M., Warmuth-Metz, M., Kortmann, R., Bison, B., Taylor, M. D., Rutkowski, S., Pfister, S. M., Jones, D. T., Gottardo, N. G., von Hoff, K., Pajtler, K. W., Ramaswamy, V. & Hansford, J. R., 2023, In: NEURO-ONCOL ADV. 5, 1, p. vdad057

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. 2022
  19. Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas

    Goschzik, T., Mynarek, M., Doerner, E., Schenk, A., Spier, I., Warmuth-Metz, M., Bison, B., Obrecht, D., Struve, N., Kortmann, R-D., Schmid, M., Aretz, S., Rutkowski, S. & Pietsch, T., 12.2022, In: ACTA NEUROPATHOL. 144, 6, p. 1143-1156 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Comprehensive profiling of myxopapillary ependymomas identifies a distinct molecular subtype with relapsing disease

    Bockmayr, M., Harnisch, K., Pohl, L. C., Schweizer, L., Mohme, T., Körner, M., Alawi, M., Suwala, A. K., Dorostkar, M. M., Monoranu, C. M., Hasselblatt, M., Wefers, A. K., Capper, D., Hench, J., Frank, S., Richardson, T. E., Tran, I., Liu, E., Snuderl, M., Engertsberger, L., Benesch, M., von Deimling, A., Obrecht, D., Mynarek, M., Rutkowski, S., Glatzel, M., Neumann, J. E. & Schüller, U., 03.10.2022, In: NEURO-ONCOLOGY. 24, 10, p. 1689-1699 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. MR Imaging and Clinical Characteristics of Diffuse Glioneuronal Tumor with Oligodendroglioma-like Features and Nuclear Clusters

    Benesch, M., Perwein, T., Apfaltrer, G., Langer, T., Neumann, A., Brecht, I. B., Schuhmann, M. U., Cario, H., Frühwald, M. C., Vollert, K., van Buiren, M., Deng, M. Y., Seitz, A., Haberler, C., Mynarek, M., Kramm, C., Sahm, F., Robe, P. A., Dankbaar, J. W., Hoff, K. V., Warmuth-Metz, M. & Bison, B., 10.2022, In: AM J NEURORADIOL. 43, 10, p. 1523-1529 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Gene expression profiling of Group 3 medulloblastomas defines a clinically tractable stratification based on KIRREL2 expression

    Korshunov, A., Okonechnikov, K., Stichel, D., Schrimpf, D., Delaidelli, A., Tonn, S., Mynarek, M., Sievers, P., Sahm, F., Jones, D. T. W., von Deimling, A., Pfister, S. M. & Kool, M., 08.2022, In: ACTA NEUROPATHOL. 144, 2, p. 339-352 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Clinical and molecular characterization of isolated M1 disease in pediatric medulloblastoma: experience from the German HIT-MED studies

    Obrecht, D., Mynarek, M., Hagel, C., Kwiecien, R., Spohn, M., Bockmayr, M., Bison, B., Pfister, S. M., Jones, D. T. W., Sturm, D., von Deimling, A., Sahm, F., von Hoff, K., Juhnke, B-O., Benesch, M., Gerber, N. U., Friedrich, C., von Bueren, A. O., Kortmann, R-D., Schwarz, R., Pietsch, T., Fleischhack, G., Schüller, U. & Rutkowski, S., 03.2022, In: J NEURO-ONCOL. 157, 1, p. 37-48 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Refining M1 stage in medulloblastoma: criteria for cerebrospinal fluid cytology and implications for improved risk stratification from the HIT-2000 trial

    Hagel, C., Sloman, V., Mynarek, M., Petrasch, K., Obrecht, D., Kühl, J., Deinlein, F., Schmid, R., von Bueren, A. O., Friedrich, C., Juhnke, B. O., Gerber, N. U., Kwiecien, R., Girschick, H., Höller, A., Zapf, A., von Hoff, K. & Rutkowski, S., 03.2022, In: EUR J CANCER. 164, p. 30-38

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Types of deviation and review criteria in pretreatment central quality control of tumor bed boost in medulloblastoma-an analysis of the German Radiotherapy Quality Control Panel in the SIOP PNET5 MB trial

    Dietzsch, S., Braesigk, A., Seidel, C., Remmele, J., Kitzing, R., Schlender, T., Mynarek, M., Geismar, D., Jablonska, K., Schwarz, R., Pazos, M., Weber, D. C., Frick, S., Gurtner, K., Matuschek, C., Harrabi, S. B., Glück, A., Lewitzki, V., Dieckmann, K., Benesch, M., Gerber, N. U., Obrecht, D., Rutkowski, S., Timmermann, B. & Kortmann, R-D., 03.2022, In: STRAHLENTHER ONKOL. 198, 3, p. 282-290 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Primary central nervous system sarcoma with DICER1 mutation-treatment results of a novel molecular entity in pediatric Peruvian patients

    Diaz Coronado, R. Y., Mynarek, M., Koelsche, C., Mora Alferez, P., Casavilca Zambrano, S., Wachtel Aptowitzer, A., Sahm, F., von Deimling, A., Schüller, U., Spohn, M., Sturm, D., Pfister, S. M., Morales La Madrid, A., Sernaque Quintana, R., Sarria Bardales, G., Negreiros Chinchihuara, T., Ojeda Medina, L., Garcia-Corrochano Medina, P., Campos Sanchez, D. A., Ponce Farfan, J., Rutkowski, S. & Garcia Leon, J. L., 15.02.2022, In: CANCER-AM CANCER SOC. 128, 4, p. 697-707 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Local and Systemic Therapy of Recurrent Medulloblastomas in Children and Adolescents: Results of the P-HIT-REZ 2005 Study

    Gaab, C., Adolph, J. E., Tippelt, S., Mikasch, R., Obrecht, D., Mynarek, M., Rutkowski, S., Pfister, S. M., Milde, T., Witt, O., Bison, B., Warmuth-Metz, M., Kortmann, R-D., Dietzsch, S., Pietsch, T., Timmermann, B., Sträter, R., Bode, U., Faldum, A., Kwiecien, R. & Fleischhack, G., 18.01.2022, In: CANCERS. 14, 3, 471.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and high-dose chemotherapy within the prospective P-HIT trial

    Juhnke, B-O., Gessi, M., Gerber, N. U., Friedrich, C., Mynarek, M., von Bueren, A. O., Haberler, C., Schüller, U., Kortmann, R-D., Timmermann, B., Bison, B., Warmuth-Metz, M., Kwiecien, R., Pfister, S. M., Spix, C., Pietsch, T., Kool, M., Rutkowski, S. & von Hoff, K., 05.01.2022, In: NEURO-ONCOLOGY. 24, 1, p. 127-137 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. 2021
  30. SIOP PNET5 MB Trial: History and Concept of a Molecularly Stratified Clinical Trial of Risk-Adapted Therapies for Standard-Risk Medulloblastoma

    Mynarek, M., Milde, T., Padovani, L., Janssens, G. O., Kwiecien, R., Mosseri, V., Clifford, S. C., Doz, F. & Rutkowski, S., 02.12.2021, In: CANCERS. 13, 23, 1677.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  31. Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies

    Adolph, J. E., Fleischhack, G., Gaab, C., Mikasch, R., Mynarek, M., Rutkowski, S., Schüller, U., Pfister, S. M., Pajtler, K. W., Milde, T., Witt, O., Bison, B., Warmuth-Metz, M., Kortmann, R-D., Dietzsch, S., Pietsch, T., Timmermann, B., Tippelt, S. & German GPOH HIT-Network, 11.2021, In: J NEURO-ONCOL. 155, 2, p. 193-202 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Therapeutic implications of improved molecular diagnostics for rare CNS-embryonal tumor entities: results of an international, retrospective study

    von Hoff, K., Haberler, C., Schmitt-Hoffner, F., Schepke, E., de Rojas, T., Jacobs, S., Zapotocky, M., Sumerauer, D., Perek-Polnik, M., Dufour, C., van Vuurden, D., Slavc, I., Gojo, J., Pickles, J. C., Gerber, N. U., Massimino, M., Gil-da-Costa, M. J., Garami, M., Kumirova, E., Sehested, A., Scheie, D., Cruz, O., Moreno, L., Cho, J., Zeller, B., Bovenschen, N., Grotzer, M., Alderete, D., Snuderl, M., Zheludkova, O., Golanov, A., Okonechnikov, K., Mynarek, M., Juhnke, B. O., Rutkowski, S., Schüller, U., Pizer, B., Zezschwitz, B. V., Kwiecien, R., Wechsung, M., Konietschke, F., Hwang, E. I., Sturm, D., Pfister, S. M., von Deimling, A., Rushing, E. J., Ryzhova, M., Hauser, P., Łastowska, M., Wesseling, P., Giangaspero, F., Hawkins, C., Figarella-Branger, D., Eberhart, C., Burger, P., Gessi, M., Korshunov, A., Jacques, T. S., Capper, D., Pietsch, T. & Kool, M., 01.09.2021, In: NEURO-ONCOLOGY. 23, 9, p. 1597-1611 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Follow-up evaluation of a web-based pediatric brain tumor board in Latin America

    Rosabal-Obando, M., Osorio, D. S., Lassaletta, A., La Madrid, A. M., Bartels, U., Finlay, J. L., Qaddoumi, I., Rutkowski, S. & Mynarek, M., 09.2021, In: PEDIATR BLOOD CANCER. 68, 9, p. e29073

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Pretreatment central quality control for craniospinal irradiation in non-metastatic medulloblastoma: First experiences of the German radiotherapy quality control panel in the SIOP PNET5 MB trial

    Dietzsch, S., Braesigk, A., Seidel, C., Remmele, J., Kitzing, R., Schlender, T., Mynarek, M., Geismar, D., Jablonska, K., Schwarz, R., Pazos, M., Walser, M., Frick, S., Gurtner, K., Matuschek, C., Harrabi, S. B., Glück, A., Lewitzki, V., Dieckmann, K., Benesch, M., Gerber, N. U., Rutkowski, S., Timmermann, B. & Kortmann, R-D., 08.2021, In: STRAHLENTHER ONKOL. 197, 8, p. 674-682 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Local and Systemic Therapy of Recurrent Ependymoma in Children and Adolescents: Short- and Long-term Results of the E-HIT-REZ 2005 Study

    Adolph, J. E., Fleischhack, G., Mikasch, R., Zeller, J., Warmuth-Metz, M., Bison, B., Mynarek, M., Rutkowski, S., Schüller, U., von Hoff, K., Obrecht, D., Pietsch, T., Pfister, S. M., Pajtler, K. W., Witt, O., Witt, H., Kortmann, R-D., Timmermann, B., Krauß, J., Frühwald, M. C., Faldum, A., Kwiecien, R., Bode, U., Tippelt, S. & German GPOH HIT-Network, 01.06.2021, In: NEURO-ONCOLOGY. 23, 6, p. 1012-1023 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Neurofibromatosis type 2 predisposes to ependymomas of various localization, histology, and molecular subtype

    Kresbach, C., Dorostkar, M. M., Suwala, A. K., Wefers, A. K., Schweizer, L., Engertsberger, L., Bison, B., Mynarek, M., Kloth-Stachnau, K., Spohn, M., von Deimling, A., Benesch, M., Hagel, C., Mautner, V-F., Rutkowski, S. & Schüller, U., 06.2021, In: ACTA NEUROPATHOL. 141, 6, p. 971-974 4 p.

    Research output: SCORING: Contribution to journalLetterResearchpeer-review

  37. Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study

    Liu, A. P. Y., Li, B. K., Pfaff, E., Gudenas, B., Vasiljevic, A., Orr, B. A., Dufour, C., Snuderl, M., Karajannis, M. A., Rosenblum, M. K., Hwang, E. I., Ng, H-K., Hansford, J. R., Szathmari, A., Faure-Conter, C., Merchant, T. E., Levine, M., Bouvier, N., von Hoff, K., Mynarek, M., Rutkowski, S., Sahm, F., Kool, M., Hawkins, C., Onar-Thomas, A., Robinson, G. W., Gajjar, A., Pfister, S. M., Bouffet, E., Northcott, P. A., Jones, D. T. W. & Huang, A., 05.2021, In: ACTA NEUROPATHOL. 141, 5, p. 771-785 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Supratentorial ependymoma in childhood: more than just RELA or YAP

    Zschernack, V., Jünger, S. T., Mynarek, M., Rutkowski, S., Garre, M. L., Ebinger, M., Neu, M., Faber, J., Erdlenbruch, B., Claviez, A., Bielack, S., Brozou, T., Frühwald, M. C., Dörner, E., Dreschmann, V., Stock, A., Solymosi, L., Hench, J., Frank, S., Vokuhl, C., Waha, A., Andreiuolo, F. & Pietsch, T., 03.2021, In: ACTA NEUROPATHOL. 141, 3, p. 455-466 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Sarcoma classification by DNA methylation profiling

    Koelsche, C., Schrimpf, D., Stichel, D., Sill, M., Sahm, F., Reuss, D. E., Blattner, M., Worst, B., Heilig, C. E., Beck, K., Horak, P., Kreutzfeldt, S., Paff, E., Stark, S., Johann, P., Selt, F., Ecker, J., Sturm, D., Pajtler, K. W., Reinhardt, A., Wefers, A. K., Sievers, P., Ebrahimi, A., Suwala, A., Fernández-Klett, F., Casalini, B., Korshunov, A., Hovestadt, V., Kommoss, F. K. F., Kriegsmann, M., Schick, M., Bewerunge-Hudler, M., Milde, T., Witt, O., Kulozik, A. E., Kool, M., Romero-Pérez, L., Grünewald, T. G. P., Kirchner, T., Wick, W., Platten, M., Unterberg, A., Uhl, M., Abdollahi, A., Debus, J., Lehner, B., Thomas, C., Hasselblatt, M., Paulus, W., Hartmann, C., Staszewski, O., Prinz, M., Hench, J., Frank, S., Versleijen-Jonkers, Y. M. H., Weidema, M. E., Mentzel, T., Griewank, K., de Álava, E., Martín, J. D., Gastearena, M. A. I., Chang, K. T-E., Low, S. Y. Y., Cuevas-Bourdier, A., Mittelbronn, M., Mynarek, M., Rutkowski, S., Schüller, U., Mautner, V. F., Schittenhelm, J., Serrano, J., Snuderl, M., Büttner, R., Klingebiel, T., Buslei, R., Gessler, M., Wesseling, P., Dinjens, W. N. M., Brandner, S., Jaunmuktane, Z., Lyskjær, I., Schirmacher, P., Stenzinger, A., Brors, B., Glimm, H., Heining, C., Tirado, O. M., Sáinz-Jaspeado, M., Mora, J., Alonso, J., Del Muro, X. G., Moran, S., Esteller, M., Benhamida, J. K., Ladanyi, M., Wardelmann, E., Antonescu, C., Flanagan, A., Dirksen, U., Hohenberger, P., Baumhoer, D., Hartmann, W., Vokuhl, C., Flucke, U., Petersen, I., Mechtersheimer, G., Capper, D., Jones, D. T. W., Fröhling, S., Pfister, S. M. & von Deimling, A., 21.01.2021, In: NAT COMMUN. 12, 1, p. 498

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Detailed Clinical and Histopathological Description of 8 Cases of Molecularly Defined CNS Neuroblastomas

    Holsten, T., Lubieniecki, F., Spohn, M., Mynarek, M., Bison, B., Löbel, U., Rutkowski, S. & Schüller, U., 01.01.2021, In: J NEUROPATH EXP NEUR. 80, 1, p. 52-59 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Defining the Spectrum, Treatment and Outcome of Patients With Genetically Confirmed Gorlin Syndrome From the HIT-MED Cohort

    Kloth, K., Obrecht, D., Sturm, D., Pietsch, T., Warmuth-Metz, M., Bison, B., Mynarek, M. & Rutkowski, S., 2021, In: FRONT ONCOL. 11, 756025.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Diagnostics and Diagnosis of Late Effects in Childhood Brain Tumour Survivors

    Tallen, G., Mynarek, M., Tischler, T., Weller, M. & Rutkowski, S. J., 2021, Late Treatment Effects and Cancer Survivor Care in the Young: From Childhood to Early Adulthood. Beck, J. D., Bokemeyer, C. & Langer, T. (eds.). 1 ed. Cham: Springer Nature Switzerland, p. 239-251 13 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesEducationpeer-review

  43. 2020
  44. Young children with medulloblastoma: Important open questions and the high-risk dilemma

    Mynarek, M. & Rutkowski, S., 18.12.2020, In: NEURO-ONCOLOGY. 22, 12, p. 1723-1724 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  45. Evaluation of Prognostic Factors and Role of Participation in a Randomized Trial or a Prospective Registry in Pediatric and Adolescent Nonmetastatic Medulloblastoma - A Report From the HIT 2000 Trial

    Dietzsch, S., Placzek, F., Pietschmann, K., von Bueren, A. O., Matuschek, C., Glück, A., Guckenberger, M., Budach, V., Welzel, J., Pöttgen, C., Schmidberger, H., Heinzelmann, F., Paulsen, F., Escudero, M. P., Schwarz, R., Hornung, D., Martini, C., Grosu, A. L., Stueben, G., Jablonska, K., Dunst, J., Stranzl-Lawatsch, H., Dieckmann, K., Timmermann, B., Pietsch, T., Warmuth-Metz, M., Bison, B., Kwiecien, R., Benesch, M., Gerber, N. U., Grotzer, M. A., Pfister, S. M., Clifford, S. C., von Hoff, K., Klagges, S., Rutkowski, S., Kortmann, R-D. & Mynarek, M., 12.12.2020, In: ADV RADIAT ONCOL. 5, 6, p. 1158-1169 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Ependymomas in infancy: underlying genetic alterations, histological features, and clinical outcome

    Jünger, S. T., Andreiuolo, F., Mynarek, M., Dörner, E., Zur Mühlen, A., Rutkowski, S., von Bueren, A. O. & Pietsch, T., 11.2020, In: CHILD NERV SYST. 36, 11, p. 2693-2700 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. CDKN2A deletion in supratentorial ependymoma with RELA alteration indicates a dismal prognosis: a retrospective analysis of the HIT ependymoma trial cohort

    Jünger, S. T., Andreiuolo, F., Mynarek, M., Wohlers, I., Rahmann, S., Klein-Hitpass, L., Dörner, E., Zur Mühlen, A., Velez-Char, N., von Hoff, K., Warmuth-Metz, M., Kortmann, R-D., Timmermann, B., von Bueren, A., Rutkowski, S. & Pietsch, T., 09.2020, In: ACTA NEUROPATHOL. 140, 3, p. 405-407 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort

    Mynarek, M., von Hoff, K., Pietsch, T., Ottensmeier, H., Warmuth-Metz, M., Bison, B., Pfister, S., Korshunov, A., Sharma, T., Jaeger, N., Ryzhova, M., Zheludkova, O., Golanov, A., Rushing, E. J., Hasselblatt, M., Koch, A., Schüller, U., von Deimling, A., Sahm, F., Sill, M., Riemenschneider, M. J., Dohmen, H., Monoranu, C. M., Sommer, C., Staszewski, O., Mawrin, C., Schittenhelm, J., Brück, W., Filipski, K., Hartmann, C., Meinhardt, M., Pietschmann, K., Haberler, C., Slavc, I., Gerber, N. U., Grotzer, M., Benesch, M., Schlegel, P. G., Deinlein, F., von Bueren, A. O., Friedrich, C., Juhnke, B-O., Obrecht, D., Fleischhack, G., Kwiecien, R., Faldum, A., Kortmann, R. D., Kool, M. & Rutkowski, S., 20.06.2020, In: J CLIN ONCOL. 38, 18, p. 2028-2040 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Molecular characterization of histopathological ependymoma variants

    Neumann, J. E., Spohn, M., Obrecht, D., Mynarek, M., Thomas, C., Hasselblatt, M., Dorostkar, M. M., Wefers, A. K., Frank, S., Monoranu, C-M., Koch, A., Witt, H., Kool, M., Pajtler, K. W., Rutkowski, S., Glatzel, M. & Schüller, U., 02.2020, In: ACTA NEUROPATHOL. 139, 2, p. 305-318 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations

    Pfaff, E., Aichmüller, C., Sill, M., Stichel, D., Snuderl, M., Karajannis, M. A., Schuhmann, M. U., Schittenhelm, J., Hasselblatt, M., Thomas, C., Korshunov, A., Rhizova, M., Wittmann, A., Kaufhold, A., Iskar, M., Ketteler, P., Lohmann, D., Orr, B. A., Ellison, D. W., von Hoff, K., Mynarek, M., Rutkowski, S., Sahm, F., von Deimling, A., Lichter, P., Kool, M., Zapatka, M., Pfister, S. M. & Jones, D. T. W., 02.2020, In: ACTA NEUROPATHOL. 139, 2, p. 243-257 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma

    Begemann, M., Waszak, S. M., Robinson, G. W., Jäger, N., Sharma, T., Knopp, C., Kraft, F., Moser, O., Mynarek, M., Guerrini-Rousseau, L., Brugieres, L., Varlet, P., Pietsch, T., Bowers, D. C., Chintagumpala, M., Sahm, F., Korbel, J. O., Rutkowski, S., Eggermann, T., Gajjar, A., Northcott, P., Elbracht, M., Pfister, S. M., Kontny, U. & Kurth, I., 01.01.2020, In: J CLIN ONCOL. 38, 1, p. 43-50 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. 2019
  53. Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features - a retrospective analysis of the HIT ependymoma trial cohort

    Jünger, S. T., Mynarek, M., Wohlers, I., Dörner, E., Mühlen, A. Z., Velez-Char, N., von Hoff, K., Rutkowski, S., Warmuth-Metz, M., Kortmann, R-D., Timmermann, B., Rahmann, S., Klein-Hitpass, L., von Bueren, A. O. & Pietsch, T., 14.11.2019, In: ACTA NEUROPATHOL COM. 7, 1, p. 181

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. Imaging Characteristics of Wingless Pathway Subgroup Medulloblastomas: Results from the German HIT/SIOP-Trial Cohort

    Stock, A., Mynarek, M., Pietsch, T., Pfister, S. M., Clifford, S. C., Goschzik, T., Sturm, D., Schwalbe, E. C., Hicks, D., Rutkowski, S., Bison, B., Pham, M. & Warmuth-Metz, M., 11.2019, In: AM J NEURORADIOL. 40, 11, p. 1811-1817 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series

    Benesch, M., Mynarek, M., Witt, H., Warmuth-Metz, M., Pietsch, T., Bison, B., Pfister, S. M., Pajtler, K. W., Kool, M., Schüller, U., Pietschmann, K., Juhnke, B-O., Tippelt, S., Fleischhack, G., Schmid, I., Kramm, C. M., Vorwerk, P., Beilken, A., Classen, C. F., Hernáiz Driever, P., Kropshofer, G., Imschweiler, T., Lemmer, A., Kortmann, R-D., Rutkowski, S. & von Hoff, K., 09.2019, In: ONCOLOGIST. 24, 9, p. e921-e929

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  56. Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes

    Sharma, T., Schwalbe, E. C., Williamson, D., Sill, M., Hovestadt, V., Mynarek, M., Rutkowski, S., Robinson, G. W., Gajjar, A., Cavalli, F., Ramaswamy, V., Taylor, M. D., Lindsey, J. C., Hill, R. M., Jäger, N., Korshunov, A., Hicks, D., Bailey, S., Kool, M., Chavez, L., Northcott, P. A., Pfister, S. M. & Clifford, S. C., 08.2019, In: ACTA NEUROPATHOL. 138, 2, p. 309-326 18 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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