Prof Dr. med. ID: 67379
Alexander Schwoerer
Publications
- 2023
Integration naturwissenschaftlicher und medizinischer Grundlagen im Hamburger Modellstudiengang Zahnmedizin iMED DENT
Bender, R., Bruhn, N., Eisenbarth, S., Lemke, R., Pantke, C-F., Hampe, W. & Schwoerer, A. P., 12.2023, In: BUNDESGESUNDHEITSBLA. 66, 12, p. 1353-1362 10 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Bridging vascular physiology to vascular medicine - an integrative laboratory class
Heinrich, T., Bähring, R., Larena-Avellaneda, A., Querengässer, J., Solbrig, O., Ehmke, H. & Schwoerer, A. P., 01.03.2023, In: ADV PHYSIOL EDUC. 47, 1, p. 97-116 20 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Education › peer-review
Fallbeispiele und Grundlagen aus der Prävention, Biochemie und Physiologie
Zyriax, B-C., Schwoerer, A. & Guse, A., 2023, Fachbuch Schwangerschaft und Stillzeit: Ernährung, Lebensstil, Prävention. Zyriax, B-C. (ed.). 1 ed. München: Elsevier GmbH, p. 7-48 41 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Transfer › peer-review
- 2022
The baroreceptor reflex brought to life outside the classroom - an e-learning based asynchronous laboratory class using a non-supervised modified Active Standing Test
Heinrich, T., Sehner, S., Wageringel, I., Ehmke, H. & Schwoerer, A. P., 01.07.2022, In: BMC MED EDUC. 22, 1, 515.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2020
Nitro-fatty acids suppress ischemic ventricular arrhythmias by preserving calcium homeostasis
Mollenhauer, M., Mehrkens, D., Klinke, A., Lange, M., Friedrich, K., Braumann, S., Geißen, S., Simskyilmaz, S., Nettersheim, F. S., Lee, S., Peinkofer, G., Geisler, A. C., Geis, B., Schwoerer, A., Carrier, L., Freeman, B. A., Dewenter, M., Luo, X., El-Armouche, A., Wagner, M., Adam, M., Baldus, S. & Rudolph, V., 18.09.2020, In: SCI REP-UK. 10, 1, 15319.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Augmentation of myocardial I-f dysregulates calcium homeostasis and causes adverse cardiac remodeling
Yampolsky, P., Koenen, M., Mosqueira, M., Geschwill, P., Nauck, S., Witzenberger, M., Seyler, C., Fink, T., Kruska, M., Bruehl, C., Schwoerer, A. P., Ehmke, H., Fink, R. H. A., Draguhn, A., Thomas, D., Katus, H. A. & Schweizer, P. A., 23.07.2019, In: NAT COMMUN. 10, 1, p. 3295Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model
Pecha, S., Yorgan, K., Röhl, M., Geertz, B., Hansen, A., Weinberger, F., Sehner, S., Ehmke, H., Reichenspurner, H., Eschenhagen, T. & Schwoerer, A. P., 08.07.2019, In: SCI REP-UK. 9, 1, p. 9831Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The heterotopic heart transplantation in mice as a small animal model to study mechanical unloading - Establishment of the procedure, perioperative management and postoperative scoring
Westhofen, S., Jelinek, M., Dreher, L., Biermann, D., Martin, J., Vitzthum, H., Reichenspurner, H., Ehmke, H. & Schwoerer, A. P., 12.04.2019, In: PLOS ONE. 14, 4, p. e0214513Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Analysis of fibrosis in control or pressure overloaded rat hearts after mechanical unloading by heterotopic heart transplantation
Schaefer, A., Schneeberger, Y., Schulz, S., Krasemann, S., Werner, T., Piasecki, A., Höppner, G., Müller, C., Morhenn, K., Lorenz, K., Wieczorek, D., Schwoerer, A. P., Eschenhagen, T., Ehmke, H., Reichenspurner, H., Stenzig, J. & Cuello, F., 05.04.2019, In: SCI REP-UK. 9, 1, p. 5710Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2018
Genetic background dominates the susceptibility to ventricular arrhythmias in a murine model of β-adrenergic stimulation
Jelinek, M., Wallach, C., Ehmke, H. & Schwoerer, A. P., 02.02.2018, In: SCI REP-UK. 8, 1, p. 2312Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Nitrated fatty acids suppress angiotensin II-mediated fibrotic remodelling and atrial fibrillation
Rudolph, T. K., Ravekes, T., Klinke, A., Friedrichs, K., Mollenhauer, M., Pekarova, M., Ambrozova, G., Martiskova, H., Kaur, J-J., Matthes, B., Schwoerer, A., Woodcock, S. R., Kubala, L., Freeman, B. A., Baldus, S. & Rudolph, V., 01.01.2016, In: CARDIOVASC RES. 109, 1, p. 174-84 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A New Animal Model for Investigation of Mechanical Unloading in Hypertrophic and Failing Hearts: Combination of Transverse Aortic Constriction and Heterotopic Heart Transplantation
Schaefer, A., Schneeberger, Y., Stenzig, J., Biermann, D., Jelinek, M., Reichenspurner, H., Eschenhagen, T., Ehmke, H. & Schwoerer, A. P., 2016, In: PLOS ONE. 11, 2, p. e0148259Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
A Comparative Analysis of Bupivacaine and Ropivacaine Effects on Human Cardiac SCN5A Channels
Schwoerer, A. P., Scheel, H. & Friederich, P., 06.2015, In: ANESTH ANALG. 120, 6, p. 1226-34Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2013
Enhanced Ca²+ influx through cardiac L-type Ca²+ channels maintains the systolic Ca²+ transient in early cardiac atrophy induced by mechanical unloading
Schwoerer, A., Neef, S., Broichhausen, I., Jacubeit, J., Tiburcy, M., Wagner, M., Biermann, D., Didié, M., Vettel, C., Maier, L. S., Zimmermann, W. H., Carrier, L., Eschenhagen, T., Volk, T., El-Armouche, A. & Ehmke, H., 01.12.2013, In: PFLUG ARCH EUR J PHY. 465, 12, p. 1763-73 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Baseline systolic left ventricular function determines hemodynamic adaptation following percutaneous mitral valve repair
Rudolph, V., Moenig, C., Lubos, E., Kalbacher, D., Knap, M., Schlüter, M., Kuß, O., Koschyk, D., Schwoerer, A. P., Treede, H., Schirmer, J., Reichenspurner, H., Ehmke, H., Blankenberg, S. & Baldus, S., 10.09.2013, In: INT J CARDIOL. 167, 6, p. 3039-40 2 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by β-adrenergic stimulation
Nebel, M., Schwoerer, A. P., Warszta, D., Siebrands, C. C., Limbrock, A-C., Swarbrick, J. M., Fliegert, R., Weber, K., Bruhn, S., Hohenegger, M., Geisler, A., Herich, L., Schlegel, S., Carrier, L., Eschenhagen, T., Potter, B. V. L., Ehmke, H. & Guse, A. H., 31.05.2013, In: J BIOL CHEM. 288, 22, p. 16017-30 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Parthenogenetic stem cells for tissue-engineered heart repair
Didié, M., Christalla, P., Rubart, M., Muppala, V., Döker, S., Unsöld, B., El-Armouche, A., Rau, T., Eschenhagen, T., Schwoerer, A. P., Ehmke, H., Schumacher, U., Fuchs, S., Lange, C., Becker, A., Tao, W., Scherschel, J. A., Soonpaa, M. H., Yang, T., Lin, Q., Zenke, M., Han, D-W., Schöler, H. R., Rudolph, C., Steinemann, D., Schlegelberger, B., Kattman, S., Witty, A., Keller, G., Field, L. J. & Zimmermann, W-H., 01.03.2013, In: J CLIN INVEST. 123, 3, p. 1285-98 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
Bupivacaine destabilizes action potential duration in cellular and computational models of long QT syndrome 1.
Schwoerer, A., Zenouzi, R., Ehmke, H. & Friederich, P., 2011, In: ANESTH ANALG. 113, 6, p. 1365-1373 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Common microRNA signatures in cardiac hypertrophic and atrophic remodeling induced by changes in hemodynamic load.
El-Armouche, A., Schwoerer, A., Neuber, C., Emmons, J., Biermann, D., Christalla, T., Grundhoff, A., Eschenhagen, T., Zimmermann, W-H. & Ehmke, H., 2010, In: PLOS ONE. 5, 12, p. 14263 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Development of a drug screening platform based on engineered heart tissue.
Hansen, A., Eder, A., Bönstrup, M., Flato, M., Mewe, M., Schaaf, S., Aksehirlioglu, B., Schwoerer, A., Uebeler, J. & Eschenhagen, T., 2010, In: CIRC RES. 107, 1, p. 35-44 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
Rudolph, V., Andrié, R. P., Rudolph, T. K., Friedrichs, K., Klinke, A., Hirsch-Hoffmann, B., Schwoerer, A., Lau, D., Fu, X., Klingel, K., Sydow, K., Didié, M., Seniuk, A., von Leitner, E-C., Szöcs, K., Schrickel, J. W., Treede, H., Wenzel, U., Lewalter, T., Nickenig, G., Zimmermann, W-H., Meinertz, T., Böger, R., Reichenspurner, H., Freeman, B. A., Eschenhagen, T., Ehmke, H., Hazen, S. L., Willems, S. & Baldus, S., 2010, In: NAT MED. 16, 4, p. 470-474 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The subtype-specific effects of droperidol on action potential duration in cellular and computational models of long QT syndrome.
Schwoerer, A., Kebernik, J., Ehmke, H. & Friederich, P., 2010, In: ANESTH ANALG. 111, 3, p. 638-646 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
Treatment with atorvastatin partially protects the rat heart from harmful catecholamine effects.
Schmechel, A., Grimm, M., El-Armouche, A., Höppner, G., Schwoerer, A., Ehmke, H. & Eschenhagen, T., 2009, In: CARDIOVASC RES. 82, 1, p. 100-106 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2008
Mechanical unloading of the rat heart involves marked changes in the protein kinase-phosphatase balance.
Schwoerer, A., Neuber, C., Schmechel, A., Melnychenko, I., Mearini, G., Boknik, P., Kirchhefer, U., Schmitz, W., Ehmke, H., Eschenhagen, T. & El-Armouche, A., 2008, In: J MOL CELL CARDIOL. 45, 6, p. 846-852 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Unloaded rat hearts in vivo express a hypertrophic phenotype of cardiac repolarization.
Schwoerer, A., Melnychenko, I., Goltz, D., Hedinger, N., Broichhausen, I., El-Armouche, A., Eschenhagen, T., Volk, T. & Ehmke, H., 2008, In: J MOL CELL CARDIOL. 45, 5, p. 633-641 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2007
Diminished Kv4.2/3 but not KChIP2 levels reduce the cardiac transient outward K+ current in spontaneously hypertensive rats.
Goltz, D., Schultz, J-H., Stucke, C., Wagner, M. E., Bassalaý, P., Schwoerer, A., Ehmke, H. & Volk, T., 2007, In: CARDIOVASC RES. 74, 1, p. 85-95 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Modulation of the transient outward K+ current by inhibition of endothelin-A receptors in normal and hypertrophied rat hearts.
Wagner, M. E., Goltz, D., Stucke, C., Schwoerer, A., Ehmke, H. & Volk, T., 2007, In: PFLUG ARCH EUR J PHY. 454, 4, p. 595-604 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molecular interaction of droperidol with human ether-a-go-go-related gene channels: prolongation of action potential duration without inducing early afterdepolarization.
Schwoerer, A., Blütner, C., Brandt, S., Binder, S., Siebrands, C., Ehmke, H. & Friederich, P., 2007, In: ANESTHESIOLOGY. 106, 5, p. 967-976 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2006
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts.
Zimmermann, W-H., Melnychenko, I., Wasmeier, G., Didié, M., Naito, H., Nixdorff, U., Hess, A., Budinsky, L., Brune, K., Michaelis, B., Dhein, S., Schwoerer, A., Ehmke, H. & Eschenhagen, T., 2006, In: NAT MED. 12, 4, p. 452-458 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2003
A polycystin-2-like large conductance cation channel in rat left ventricular myocytes.
Volk, T., Schwoerer, A., Thiessen, S., Schultz, J-H. & Ehmke, H., 2003, In: CARDIOVASC RES. 58, 1, p. 76-88 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review