The subtype-specific effects of droperidol on action potential duration in cellular and computational models of long QT syndrome.

Abstract

Droperidol is a highly potent butyrophenone used for the therapy of postoperative nausea and vomiting. Its cardiac safety in cardiovascular-healthy patients and those with long QT (LQT) syndrome is a matter of debate. In this study, we investigated whether droperidol has subtype-specific effects in cellular and computational models of LQT syndrome.

Bibliographical data

Original languageGerman
Article number3
ISSN0003-2999
Publication statusPublished - 2010
pubmed 20601449