Prof.Dr.med. ID: 54687
Tobias Lange
Publications
- 2024
Comparison of ex vivo bioluminescence imaging, Alu-qPCR and histology for the quantification of spontaneous lung and bone metastases in subcutaneous xenograft mouse models
Haider, M-T., Freytag, V., Krause, L., Spethmann, T., Gosau, T., Beine, M. C., Knies, C., Schröder-Schwarz, J., Horn, M., Riecken, K. & Lange, T., 04.2024, In: CLIN EXP METASTAS. 41, 2, p. 103-115 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Microplastics role in cell migration and distribution during cancer cell division
Brynzak-Schreiber, E., Schögl, E., Bapp, C., Cseh, K., Kopatz, V., Jakupec, M. A., Weber, A., Lange, T., Toca-Herrera, J. L., Del Favero, G., Wadsak, W., Kenner, L. & Pichler, V., 04.2024, In: CHEMOSPHERE. 353, p. 141463Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria-related pathways in colorectal cancer
Everest-Dass, A., Nersisyan, S., Maar, H., Novosad, V., Schröder-Schwarz, J., Freytag, V., Stuke, J. L., Beine, M. C., Schiecke, A., Haider, M-T., Kriegs, M., Elakad, O., Bohnenberger, H., Conradi, L-C., Raygorodskaya, M., Krause, L., von Itzstein, M., Tonevitsky, A., Schumacher, U., Maltseva, D., Wicklein, D. & Lange, T., 01.2024, In: MOL ONCOL. 18, 1, p. 62-90 29 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ALDH1A1 drives prostate cancer metastases and radioresistance by interplay with AR- and RAR-dependent transcription
Gorodetska, I., Offermann, A., Püschel, J., Lukiyanchuk, V., Gaete, D., Kurzyukova, A., Freytag, V., Haider, M-T., Fjeldbo, C. S., Di Gaetano, S., Schwarz, F. M., Patil, S., Borkowetz, A., Erb, H. H. H., Baniahmad, A., Mircetic, J., Lyng, H., Löck, S., Linge, A., Lange, T., Knopf, F., Wielockx, B., Krause, M., Perner, S. & Dubrovska, A., 2024, In: THERANOSTICS. 14, 2, p. 714-737 24 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Multimodal image-guided laser ablation system for precise 3D tissue sampling and subsequent analysis of biomolecules for cancer research
Hahn, J., Moritz, M., Walter, A., Wieck, T., Moustafa, A., Mansour, W. Y., Harms, C., Stenzel, P., Heeren, J., Haider, M-T., Lange, T. & Schlüter, H., 2024, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXII: 29-31 January 2024, San Francisco, California, United States. Tárnok, A. & Houston, J. P. (eds.). 1 ed. Bellingham, Washington: SPIE , 128460C. (Proceedings of SPIE; vol. 12846).Research output: SCORING: Contribution to book/anthology › Conference contribution - Article for conference › Research › peer-review
- 2023
Identification of potential classes of glycoligands mediating dynamic endothelial adhesion of human tumor cells
Starzonek, S., Maar, H., Mereiter, S., Freytag, V., Haider, M-T., Riecken, K., Huang, Y-L., Jacob, F., Wicklein, D., Schumacher, U. & Lange, T., 06.10.2023, In: GLYCOBIOLOGY. 33, 8, p. 637-650 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dynamics of CXCR4 positive circulating tumor cells in prostate cancer patients during radiotherapy
Klusa, D., Lohaus, F., Franken, A., Baumbach, M., Cojoc, M., Dowling, P., Linge, A., Offermann, A., Löck, S., Hušman, D., Rivandi, M., Polzer, B., Freytag, V., Lange, T., Neubauer, H., Kücken, M., Perner, S., Hölscher, T., Dubrovska, A., Krause, M., Kurth, I., Baumann, M. & Peitzsch, C., 15.06.2023, In: INT J CANCER. 152, 12, p. 2639-2654 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Efficacy of zoledronic acid for the elimination of disseminated tumor cells in a clinically relevant, spontaneously metastatic prostate cancer xenograft model
Böckelmann, L. C., Freytag, V., Ahlers, A-K., Maar, H., Gosau, T., Baranowsky, A., Schmitz, R., Pantel, K., Schumacher, U., Haider, M-T. & Lange, T., 06.2023, In: BONE. 171, p. 116741Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo
Genduso, S., Freytag, V., Schetler, D., Kirchner, L., Schiecke, A., Maar, H., Wicklein, D., Gebauer, F., Bröker, K., Stürken, C., Milde-Langosch, K., Oliveira-Ferrer, L., Ricklefs, F. L., Ewald, F., Wolters-Eisfeld, G., Riecken, K., Unrau, L., Krause, L., Bohnenberger, H., Offermann, A., Perner, S., Sebens, S., Lamszus, K., Diehl, L., Linder, S., Jücker, M., Schumacher, U. & Lange, T., 17.03.2023, In: J HEMATOL ONCOL. 16, 1, 23.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Ex Vivo Model of Neuroblastoma Plasticity
Schäfer, P., Muhs, S., Turnbull, L., Garwal, P., Maar, H., Yorgan, T. A., Tolosa, E., Lange, T. & Windhorst, S., 17.02.2023, In: CANCERS. 15, 4, 1274.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
Giannou, A. D., Kempski, J., Shiri, A. M., Lücke, J., Zhang, T., Zhao, L., Zazara, D. E., Cortesi, F., Riecken, K., Amezcua Vesely, M. C., Low, J. S., Xu, H., Kaffe, E., Garcia-Perez, L., Agalioti, T., Yamada, Y., Jungraithmayr, W., Zigmond, E., Karstens, K-F., Steglich, B., Wagner, J., Konczalla, L., Carambia, A., Schulze, K., von Felden, J., May, P., Briukhovetska, D., Bedke, T., Brockmann, L., Starzonek, S., Lange, T., Koch, C., Riethdorf, S., Pelczar, P., Böttcher, M., Sabihi, M., Huber, F. J., Reeh, M., Grass, J. K., Wahib, R., Seese, H., Stüben, B-O., Fard-Aghaie, M., Duprée, A., Scognamiglio, P., Plitzko, G., Meiners, J., Soukou, S., Wittek, A., Manthey, C., Maroulis, I. C., Arck, P. C., Perez, D., Gao, B., Zarogiannis, S. G., Strowig, T., Pasqualini, R., Arap, W., Gosálvez, J. S., Kobold, S., Prinz, I., Guse, A. H., Tachezy, M., Ghadban, T., Heumann, A., Li, J., Melling, N., Mann, O., Izbicki, J. R., Pantel, K., Schumacher, U., Lohse, A. W., Flavell, R. A., Gagliani, N. & Huber, S., 10.01.2023, In: IMMUNITY. 56, 1, p. 125-142.e12Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The chemicals between us: First results of the cluster analyses on anatomy embalming procedures in the German-speaking countries
Kerner, A. M., Biedermann, U., Bräuer, L., Caspers, S., Doll, S., Engelhardt, M., Filler, T. J., Ghebremedhin, E., Gundlach, S., Hayn-Leichsenring, G. U., Heermann, S., Hettwer-Steeger, I., Hiepe, L., Hirt, B., Hirtler, L., Hörmann, R., Kulisch, C., Lange, T., Leube, R., Meuser, A. H., Müller-Gerbl, M., Nassenstein, C., Neckel, P. H., Nimtschke, U., Paulsen, F., Prescher, A., Pretterklieber, M., Schliwa, S., Schmidt, K., Schmiedl, A., Schomerus, C., Schulze-Tanzil, G., Schumacher, U., Schumann, S., Spindler, V., Streicher, J., Tschernig, T., Unverzagt, A., Valentiner, U., Viebahn, C., Wedel, T., Weigner, J., Weninger, W. W., Westermann, J., Weyers, I., Waschke, J. & Hammer, N., 2023, In: ANAT SCI EDUC. 16, 5, p. 814-829 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis
Wang, Y., Liu, X., Obser, T., Bauer, A. T., Heyes, M., Starzonek, S., Zulal, M., Opitz, K., Ott, L., Riethdorf, S., Lange, T., Pantel, K., Bendas, G., Schneider, S. W., Kusche-Gullberg, M. & Gorzelanny, C., 08.2022, In: MATRIX BIOL. 111, p. 76-94 19 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Activation of CD44/PAK1/AKT signaling promotes resistance to FGFR1 inhibition in squamous-cell lung cancer
Elakad, O., Häupl, B., Labitzky, V., Yao, S., Küffer, S., von Hammerstein-Equord, A., Danner, B. C., Jücker, M., Urlaub, H., Lange, T., Ströbel, P., Oellerich, T. & Bohnenberger, H., 19.07.2022, In: NPJ PRECIS ONCOL. 6, 1, 52.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumor cell E-selectin ligands determine partialefficacy of bortezomib on spontaneous lung metastasis formation of solid human tumors in vivo
Lange, T., Valentiner, U., Wicklein, D., Maar, H., Labitzky, V., Ahlers, A-K., Starzonek, S., Genduso, S., Staffeldt, L., Pahlow, C., Dück, A-M., Stürken, C., Baranowsky, A., Bauer, A. T., Bulk, E., Schwab, A., Riecken, K., Börnchen, C., Kiefmann, R., Abraham, V., DeLisser, H. M., Gemoll, T., Habermann, J. K., Block, A., Pantel, K. & Schumacher, U., 06.04.2022, In: MOL THER. 30, 4, p. 1536-1552 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo
Oh-Hohenhorst, S. J., Tilki, D., Ahlers, A-K., Suling, A., Hahn, O., Tennstedt, P., Matuszcak, C., Maar, H., Labitzky, V., Hanika, S., Starzonek, S., Baumgart, S., Johnsen, S. A., Kluth, M., Sirma, H., Simon, R., Sauter, G., Huland, H., Schumacher, U. & Lange, T., 01.2022, In: CANCER GENE THER. 29, 1, p. 49-61 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low expression of CD24 is associated with poor survival in colorectal cancer
Nersisyan, S., Ahlers, A-K., Lange, T., Wicklein, D., Galatenko, A., Bohnenberger, H., Elakad, O., Conradi, L-C., Genduso, S., Maar, H., Schiecke, A., Maltseva, D., Raygorodskaya, M., Makarova, J., Schumacher, U. & Tonevitsky, A., 01.2022, In: BIOCHIMIE. 192, p. 91-101 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of Spontaneous Bone Metastases of Solid Human Tumor Xenografts in Mice
Freytag, V., Valentiner, U. & Lange, T., 2022, Bioluminescence: Methods and Protocols. Kim, S-B. (ed.). 4 ed. New York, NY: Humana Press, Vol. 1. p. 317-325 9 p. (Methods in Molecular Biology; vol. 2524).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2021
Site-specific N-glycosylation of integrin α2 mediates collagen-dependent cell survival
Huang, Y-L., Liang, C-Y., Labitzky, V., Ritz, D., Oliveira, T., Cumin, C., Estermann, M., Lange, T., Everest-Dass, A. V. & Jacob, F., 22.10.2021, In: ISCIENCE. 24, 10, 103168.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of Metastasis-Related microRNAs in Prostate Cancer Progression and Treatment
Oh-Hohenhorst, S. J. & Lange, T., 06.09.2021, In: CANCERS. 13, 17Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src-family kinases as prognostic markers and potential targets
Bußmann, L., Hoffer, K., von Bargen, C. M., Droste, C., Lange, T., Kemmling, J., Schröder-Schwarz, J., Vu, A. T., Akingunsade, L., Nollau, P., Rangarajan, S., de Wijn, R., Oetting, A., Müller, C., Böckelmann, L. C., Zech, H. B., Berger, J. C., Möckelmann, N., Busch, C-J., Böttcher, A., Gatzemeier, F., Klinghammer, K., Simnica, D., Binder, M., Struve, N., Rieckmann, T., Schumacher, U., Clauditz, T. S., Betz, C. S., Petersen, C., Rothkamm, K., Münscher, A. & Kriegs, M., 01.09.2021, In: INT J CANCER. 149, 5, p. 1166 - 1180 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets
Spethmann, T., Böckelmann, L. C., Labitzky, V., Ahlers, A-K., Schröder-Schwarz, J., Bonk, S., Simon, R., Sauter, G., Huland, H., Kypta, R., Schumacher, U. & Lange, T., 07.2021, In: MOL ONCOL. 15, 7, p. 1956-1969 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression
Kemper, M., Schiecke, A., Maar, H., Nikulin, S., Poloznikov, A., Galatenko, V., Tachezy, M., Gebauer, F., Lange, T., Riecken, K., Tonevitsky, A., Aigner, A., Izbicki, J., Schumacher, U. & Wicklein, D., 26.06.2021, In: J EXP CLIN CANC RES. 40, 1, p. 214Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis
Hinz, N., Baranowsky, A., Horn, M., Kriegs, M., Sibbertsen, F., Smit, D. J., Clezardin, P., Lange, T., Schinke, T. & Jücker, M., 18.02.2021, In: CELLS-BASEL. 10, 2, 430.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Procalcitonin Exerts a Mediator Role in Septic Shock Through the Calcitonin Gene-Related Peptide Receptor
Baranowsky, A., Appelt, J., Kleber, C., Lange, T., Ludewig, P., Jahn, D., Pandey, P., Keller, D., Rose, T., Schetler, D., Braumüller, S., Huber-Lang, M., Tsitsilonis, S., Yorgan, T. A., Frosch, K-H., Amling, M., Schinke, T. & Keller, J., 01.01.2021, In: CRIT CARE MED. 49, 1, p. e41-e52Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy
Mukha, A., Kahya, U., Linge, A., Chen, O., Löck, S., Lukiyanchuk, V., Richter, S., Alves, T. C., Peitzsch, M., Telychko, V., Skvortsov, S., Negro, G., Aschenbrenner, B., Skvortsova, I-I., Mirtschink, P., Lohaus, F., Hölscher, T., Neubauer, H., Rivandi, M., Labitzky, V., Lange, T., Franken, A., Behrens, B., Stoecklein, N. H., Toma, M., Sommer, U., Zschaeck, S., Rehm, M., Eisenhofer, G., Schwager, C., Abdollahi, A., Groeben, C., Kunz-Schughart, L. A., Baretton, G. B., Baumann, M., Krause, M., Peitzsch, C. & Dubrovska, A., 2021, In: THERANOSTICS. 11, 16, p. 7844-7868 25 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The Role of Platelet Cell Surface P-Selectin for the Direct Platelet-Tumor Cell Contact During Metastasis Formation in Human Tumors
Fabricius, H-Å., Starzonek, S. & Lange, T., 2021, In: FRONT ONCOL. 11, p. 642761Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2020
Glioma escape signature and clonal development under immune pressure
Maire, C. L., Mohme, M., Bockmayr, M., Fita, K. D., Riecken, K., Börnigen, D., Alawi, M., Failla, A. V., Kolbe, K., Zapf, S., Holz, M., Neumann, K., Dührsen, L., Lange, T., Fehse, B., Westphal, M. & Lamszus, K., 01.10.2020, In: J CLIN INVEST. 130, 10, p. 5257-5271 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Xenograft-derived mRNA/miR and protein interaction networks of systemic dissemination in human prostate cancer
Lange, T., Samatov, T. R., Galatenko, V. V., Steffen, P., von Kriegstein, H., Spethmann, T., Wicklein, D., Maar, H., Kupfernagel, K., Labitzky, V., Hanika, S., Starzonek, S., Ahlers, A-K., Riecken, K., Simon, R., Polonski, A., Sauter, G., Schlomm, T., Huland, H., Johnsen, S. A., Schlüter, H., Tonevitsky, A. G. & Schumacher, U., 09.2020, In: EUR J CANCER. 137, p. 93-107 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Systematic analysis of the human tumor cell binding to human vs. murine E- and P-selectin under static vs. dynamic conditions
Starzonek, S., Maar, H., Labitzky, V., Wicklein, D., Rossdam, C., Buettner, F. F. R., Wolters-Eisfeld, G., Guengoer, C., Wagener, C., Schumacher, U. & Lange, T., 20.08.2020, In: GLYCOBIOLOGY. 30, 9, p. 695-709 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The initial engraftment of tumor cells is critical for the future growth pattern: a mathematical study based on simulations and animal experiments
Hoffmann, B., Lange, T., Labitzky, V., Riecken, K., Wree, A., Schumacher, U. & Wedemann, G., 05.06.2020, In: BMC CANCER. 20, 1, p. 524Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Modeling Spontaneous Bone Metastasis Formation of Solid Human Tumor Xenografts in Mice
Labitzky, V., Baranowsky, A., Maar, H., Hanika, S., Starzonek, S., Ahlers, A-K., Stübke, K., Koziolek, E. J., Heine, M., Schäfer, P., Windhorst, S., Jücker, M., Riecken, K., Amling, M., Schinke, T., Schumacher, U., Valentiner, U. & Lange, T., 07.02.2020, In: CANCERS. 12, 2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
A functional ex vivo assay to detect PARP1-EJ repair and radiosensitization by PARP-inhibitor in prostate cancer
Köcher, S., Beyer, B., Lange, T., Nordquist, L., Volquardsen, J., Burdak-Rothkamm, S., Schlomm, T., Petersen, C., Rothkamm, K. & Mansour, W. Y., 01.04.2019, In: INT J CANCER. 144, 7, p. 1685-1696 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Probennahme per Laserablation von Krebsgeweben für Proteomics
Lange, T. & Schlüter, H., 2019, In: BIOspektrum. 25, 1, p. 32-34Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
- 2018
Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer
Lange, T., Oh-Hohenhorst, S. J., Joosse, S. A., Pantel, K., Hahn, O., Gosau, T., Dyshlovoy, S. A., Wellbrock, J., Feldhaus, S., Maar, H., Gehrcke, R., Kluth, M., Simon, R., Schlomm, T., Huland, H. & Schumacher, U., 03.12.2018, In: SCI REP-UK. 8, p. 17535Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical relevance of cytoskeleton associated proteins for ovarian cancer
Schiewek, J., Schumacher, U., Lange, T., Joosse, S. A., Wikman, H., Pantel, K., Mikhaylova, M., Kneussel, M., Linder, S., Schmalfeldt, B., Oliveira-Ferrer, L. & Windhorst, S., 11.2018, In: J CANCER RES CLIN. 144, 11, p. 2195-2205 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Differential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Metastases
Hänel, L., Gosau, T., Maar, H., Valentiner, U., Schumacher, U., Riecken, K., Windhorst, S., Hansen, N-O., Heikaus, L., Wurlitzer, M., Nolte, I., Schlüter, H. & Lange, T., 09.2018, In: SCI REP-UK. 8, 1, p. 13986Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells
Wicklein, D., Otto, B., Suling, A., Elies, E., Lüers, G., Lange, T., Feldhaus, S., Maar, H., Schröder-Schwarz, J., Brunner, G., Wagener, C. & Schumacher, U., 08.08.2018, In: SCI REP-UK. 8, p. 11893Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effect of the actin- and calcium-regulating activities of ITPKB on the metastatic potential of lung cancer cells
Bäder, S., Glaubke, E., Grüb, S., Muhs, S., Wellbrock, J., Nalaskowski, M., Lange, T. & Windhorst, S., 26.06.2018, In: BIOCHEM J. 475, 12, p. 2057-2071 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Locally Ablative Radiation Therapy of a Primary Human Small Cell Lung Cancer Tumor Decreases the Number of Spontaneous Metastases in Two Xenograft Models
Frenzel, T., Siekmann, J., Grohmann, C., Valentiner, U., Schmitz, R., Riecken, K., Fehse, B., Schumacher, U., Lange, T. & Krüll, A., 15.03.2018, In: INT J RADIAT ONCOL. 100, 4, p. 1044-1056 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Knockdown of L1CAM significantly reduces metastasis in a xenograft model of human melanoma: L1CAM is a potential target for anti-melanoma therapy
Ernst, A-K., Putscher, A., Samatov, T. R., Suling, A., Galatenko, V. V., Shkurnikov, M. Y., Knyazev, E. N., Tonevitsky, A. G., Haalck, T., Lange, T., Maar, H., Schröder-Schwarz, J., Riecken, K., Schumacher, U. & Wicklein, D., 2018, In: PLOS ONE. 13, 2, p. e0192525Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2017
Strong fascin expression promotes metastasis independent of its F-actin bundling activity
Heinz, L. S., Muhs, S., Schiewek, J., Grüb, S., Nalaskowski, M., Lin, Y-N., Wikman, H., Oliveira-Ferrer, L., Lange, T., Wellbrock, J., Konietzny, A., Mikhaylova, M. & Windhorst, S., 15.12.2017, In: ONCOTARGET. 8, 66, p. 110077-110091 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Intracellular and extracellular microRNA: An update on localization and biological role
Makarova, J. A., Shkurnikov, M. U., Wicklein, D., Lange, T., Samatov, T. R., Turchinovich, A. A. & Tonevitsky, A. G., 11.2016, In: PROG HISTOCHEM CYTO. 51, 3-4, p. 33-49 17 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selection and Characterization of an α6β4 Integrin blocking DNA Aptamer
Berg, K., Lange, T., Mittelberger, F., Schumacher, U. & Hahn, U., 15.03.2016, In: MOL THER-NUCL ACIDS. 5, p. e294Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating S100A4
Grottke, A., Ewald, F., Lange, T., Nörz, D., Herzberger, C., Bach, J., Grabinski, N., Gräser, L., Höppner, F., Nashan, B., Schumacher, U. & Jücker, M., 2016, In: PLOS ONE. 11, 1, p. e0146370Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer
Dyshlovoy, S. A., Otte, K., Alsdorf, W. H., Hauschild, J., Lange, T., Venz, S., Bauer, C. K., Bähring, R., Amann, K., Mandanchi, R., Schumacher, U., Schröder-Schwarz, J., Makarieva, T. N., Guzii, A. G., Tabakmakher, K. M., Fedorov, S. N., Shubina, L. K., Kasheverov, I. E., Ehmke, H., Steuber, T., Stonik, V. A., Bokemeyer, C., Honecker, F. & von Amsberg, G., 2016, In: ONCOTARGET. 7, 43, p. 69703 - 69717Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion
Lin, Y-N., Bhuwania, R., Gromova, K., Failla, A. V., Lange, T., Riecken, K., Linder, S., Kneussel, M., Izbicki, J. R. & Windhorst, S., 30.07.2015, In: ONCOTARGET. 6, 21, p. 18577-89 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2014
Importance of altered glycoprotein-bound N- and O-glycans for epithelial-to-mesenchymal transition and adhesion of cancer cells
Lange, T., Samatov, T. R., Tonevitsky, A. G. & Schumacher, U., 07.05.2014, In: CARBOHYD RES. 389, p. 39-45 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Aberrant presentation of HPA-reactive carbohydrates implies Selectin-independent metastasis formation in human prostate cancer
Lange, T., Kupfernagel, M., Wicklein, D., Gebauer, F., Maar, H., Brügge, K., Müller, I., Simon, R., Schlomm, T., Sauter, G. & Schumacher, U., 01.04.2014, In: CLIN CANCER RES. 20, 7, p. 1791-802 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of DIAPH1 is up-regulated in colorectal cancer and its down-regulation strongly reduces the metastatic capacity of colon carcinoma cells
Lin, Y-N., Izbicki, J. R., König, A., Habermann, J. K., Blechner, C., Lange, T., Schumacher, U. & Windhorst, S., 01.04.2014, In: INT J CANCER. 134, 7, p. 1571-82 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review